Incidental Mutation 'R9269:Col15a1'
| ID |
702738 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Col15a1
|
| Ensembl Gene |
ENSMUSG00000028339 |
| Gene Name |
collagen, type XV, alpha 1 |
| Synonyms |
|
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.082)
|
| Stock # |
R9269 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
47208161-47313167 bp(+) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
G to C
at 47288200 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118637
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000082303]
[ENSMUST00000102917]
[ENSMUST00000107731]
[ENSMUST00000140413]
[ENSMUST00000146967]
|
| AlphaFold |
O35206 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000082303
|
| SMART Domains |
Protein: ENSMUSP00000080921
Gene: ENSMUSG00000028339
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
31 |
N/A |
INTRINSIC |
|
TSPN
|
40 |
228 |
2.53e-56 |
SMART |
|
LamG
|
89 |
227 |
1.7e-7 |
SMART |
|
low complexity region
|
236 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
332 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
541 |
567 |
N/A |
INTRINSIC |
|
Pfam:Collagen
|
603 |
663 |
1.4e-10 |
PFAM |
|
Pfam:Collagen
|
650 |
719 |
2.1e-9 |
PFAM |
|
low complexity region
|
722 |
742 |
N/A |
INTRINSIC |
|
low complexity region
|
750 |
759 |
N/A |
INTRINSIC |
|
Pfam:Collagen
|
782 |
832 |
2.7e-10 |
PFAM |
|
Pfam:Collagen
|
838 |
894 |
5.1e-10 |
PFAM |
|
low complexity region
|
965 |
980 |
N/A |
INTRINSIC |
|
low complexity region
|
1010 |
1020 |
N/A |
INTRINSIC |
|
Pfam:Endostatin
|
1087 |
1164 |
9.3e-15 |
PFAM |
|
Pfam:Endostatin
|
1148 |
1345 |
1.4e-97 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102917
|
| SMART Domains |
Protein: ENSMUSP00000099981
Gene: ENSMUSG00000028339
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
31 |
N/A |
INTRINSIC |
|
TSPN
|
40 |
228 |
2.53e-56 |
SMART |
|
LamG
|
89 |
227 |
1.7e-7 |
SMART |
|
low complexity region
|
236 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
332 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
541 |
567 |
N/A |
INTRINSIC |
|
Pfam:Collagen
|
603 |
666 |
5.6e-10 |
PFAM |
|
Pfam:Collagen
|
659 |
720 |
3.1e-10 |
PFAM |
|
low complexity region
|
737 |
764 |
N/A |
INTRINSIC |
|
low complexity region
|
772 |
781 |
N/A |
INTRINSIC |
|
Pfam:Collagen
|
804 |
854 |
9.5e-10 |
PFAM |
|
Pfam:Collagen
|
860 |
916 |
1.8e-9 |
PFAM |
|
low complexity region
|
987 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1032 |
1042 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1109 |
N/A |
INTRINSIC |
|
Pfam:Endostatin
|
1112 |
1362 |
2.8e-102 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107731
|
| SMART Domains |
Protein: ENSMUSP00000103359
Gene: ENSMUSG00000028339
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Collagen
|
6 |
81 |
6.5e-9 |
PFAM |
|
Pfam:Collagen
|
48 |
102 |
3.8e-8 |
PFAM |
|
low complexity region
|
153 |
168 |
N/A |
INTRINSIC |
|
Pfam:Collagen
|
196 |
258 |
4.1e-8 |
PFAM |
|
Pfam:Endostatin
|
275 |
355 |
2.5e-15 |
PFAM |
|
Pfam:Endostatin
|
336 |
533 |
2.8e-98 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000140413
|
| SMART Domains |
Protein: ENSMUSP00000119292
Gene: ENSMUSG00000028339
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Collagen
|
27 |
121 |
7.6e-8 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000146967
|
| SMART Domains |
Protein: ENSMUSP00000118637
Gene: ENSMUSG00000028339
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Collagen
|
2 |
55 |
6.3e-11 |
PFAM |
|
Pfam:Collagen
|
96 |
141 |
2.9e-7 |
PFAM |
|
| Meta Mutation Damage Score |
0.0846 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration. [provided by RefSeq, May 2013]
PHENOTYPE: Homozygous mutation of this gene results in abnormal muscle cells of variable size (including atrophic and split muscle cells), susceptibility to exercise-induced muscle injury, and abnormalities in heart and skeletal muscle capillary endothelium. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2m |
T |
C |
6: 121,637,865 (GRCm39) |
S845P |
probably benign |
Het |
| Actn1 |
T |
A |
12: 80,219,745 (GRCm39) |
N709Y |
probably benign |
Het |
| Alox5ap |
A |
G |
5: 149,216,006 (GRCm39) |
Y64C |
probably damaging |
Het |
| Anapc4 |
T |
A |
5: 53,018,620 (GRCm39) |
S521T |
possibly damaging |
Het |
| Ap3b1 |
C |
A |
13: 94,540,570 (GRCm39) |
P164Q |
probably damaging |
Het |
| Arhgef26 |
A |
G |
3: 62,247,920 (GRCm39) |
N335D |
probably damaging |
Het |
| Arrdc2 |
G |
A |
8: 71,288,973 (GRCm39) |
A354V |
probably benign |
Het |
| Atg2b |
A |
G |
12: 105,618,359 (GRCm39) |
S898P |
probably damaging |
Het |
| Atxn1 |
T |
A |
13: 45,710,680 (GRCm39) |
T751S |
probably benign |
Het |
| Begain |
T |
A |
12: 108,999,119 (GRCm39) |
R551W |
possibly damaging |
Het |
| Borcs8 |
C |
A |
8: 70,594,521 (GRCm39) |
D15E |
probably benign |
Het |
| Btbd16 |
C |
T |
7: 130,417,516 (GRCm39) |
R344C |
probably damaging |
Het |
| Card11 |
A |
T |
5: 140,892,516 (GRCm39) |
M183K |
probably damaging |
Het |
| Cldn3 |
T |
C |
5: 135,015,579 (GRCm39) |
L94P |
probably damaging |
Het |
| Clvs2 |
A |
T |
10: 33,419,422 (GRCm39) |
Y211N |
probably damaging |
Het |
| Cop1 |
C |
T |
1: 159,116,553 (GRCm39) |
P409L |
probably benign |
Het |
| Cplane1 |
A |
C |
15: 8,248,500 (GRCm39) |
Q1683P |
probably damaging |
Het |
| Crhbp |
C |
A |
13: 95,573,024 (GRCm39) |
A241S |
probably benign |
Het |
| Cyfip1 |
C |
A |
7: 55,557,179 (GRCm39) |
S794* |
probably null |
Het |
| Dlg5 |
T |
A |
14: 24,242,881 (GRCm39) |
H172L |
probably damaging |
Het |
| Doc2a |
T |
A |
7: 126,450,159 (GRCm39) |
I199N |
probably benign |
Het |
| Dock3 |
T |
C |
9: 106,818,522 (GRCm39) |
T1191A |
probably benign |
Het |
| Efcab8 |
G |
C |
2: 153,646,861 (GRCm39) |
V397L |
unknown |
Het |
| Eif4a3l2 |
C |
T |
6: 116,529,317 (GRCm39) |
T398I |
probably damaging |
Het |
| Fcgr1 |
C |
T |
3: 96,193,154 (GRCm39) |
R281H |
probably benign |
Het |
| Fndc10 |
T |
C |
4: 155,779,205 (GRCm39) |
V83A |
possibly damaging |
Het |
| Galnt2 |
T |
A |
8: 125,065,202 (GRCm39) |
I444K |
probably benign |
Het |
| Gcnt3 |
T |
C |
9: 69,941,290 (GRCm39) |
Y426C |
probably damaging |
Het |
| Gtpbp1 |
C |
T |
15: 79,601,855 (GRCm39) |
R533C |
probably damaging |
Het |
| Hid1 |
T |
C |
11: 115,252,502 (GRCm39) |
E60G |
probably damaging |
Het |
| Ighv1-81 |
A |
T |
12: 115,884,161 (GRCm39) |
L30Q |
possibly damaging |
Het |
| Ighv5-8 |
TATATATATATATATATATATA |
TATATATATATATATATATATATA |
12: 113,618,565 (GRCm39) |
|
probably null |
Het |
| Ilrun |
A |
C |
17: 28,005,049 (GRCm39) |
Y169* |
probably null |
Het |
| Klf10 |
A |
G |
15: 38,298,002 (GRCm39) |
L44P |
probably damaging |
Het |
| Lamc3 |
T |
C |
2: 31,813,017 (GRCm39) |
V1001A |
probably benign |
Het |
| Lamc3 |
C |
A |
2: 31,818,908 (GRCm39) |
S1211* |
probably null |
Het |
| Lmx1a |
T |
A |
1: 167,658,194 (GRCm39) |
H192Q |
probably benign |
Het |
| Nkx2-4 |
T |
C |
2: 146,926,184 (GRCm39) |
H226R |
possibly damaging |
Het |
| Or2d2 |
T |
C |
7: 106,727,833 (GRCm39) |
I256V |
probably benign |
Het |
| Or4a68 |
T |
A |
2: 89,270,276 (GRCm39) |
M116L |
probably damaging |
Het |
| Or4k37 |
T |
C |
2: 111,159,297 (GRCm39) |
F178L |
probably damaging |
Het |
| Or4p18 |
G |
A |
2: 88,232,586 (GRCm39) |
R231C |
probably benign |
Het |
| Or5b101 |
T |
C |
19: 13,004,994 (GRCm39) |
H233R |
probably benign |
Het |
| Or5b114-ps1 |
A |
T |
19: 13,353,004 (GRCm39) |
N226I |
unknown |
Het |
| Or5p52 |
T |
A |
7: 107,502,527 (GRCm39) |
I201N |
possibly damaging |
Het |
| Or7e175 |
T |
C |
9: 20,048,757 (GRCm39) |
M115T |
probably damaging |
Het |
| Or8k1 |
T |
C |
2: 86,047,247 (GRCm39) |
H269R |
probably damaging |
Het |
| Orai3 |
G |
T |
7: 127,373,194 (GRCm39) |
A232S |
probably benign |
Het |
| Pak1ip1 |
G |
A |
13: 41,162,727 (GRCm39) |
G177R |
probably benign |
Het |
| Pcp4l1 |
T |
C |
1: 171,001,975 (GRCm39) |
R62G |
possibly damaging |
Het |
| Phox2b |
T |
A |
5: 67,256,064 (GRCm39) |
Q74L |
probably benign |
Het |
| Pi4kb |
A |
G |
3: 94,891,797 (GRCm39) |
Y159C |
probably damaging |
Het |
| Pkd1l3 |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
8: 110,350,827 (GRCm39) |
|
probably benign |
Het |
| Plxna1 |
T |
C |
6: 89,306,541 (GRCm39) |
R1430G |
probably null |
Het |
| Plxna4 |
T |
C |
6: 32,155,315 (GRCm39) |
H1543R |
probably benign |
Het |
| Prcc |
A |
T |
3: 87,777,038 (GRCm39) |
F312Y |
probably damaging |
Het |
| Ranbp6 |
A |
G |
19: 29,787,388 (GRCm39) |
L988P |
probably damaging |
Het |
| Rbm27 |
A |
G |
18: 42,460,572 (GRCm39) |
T840A |
probably benign |
Het |
| Rchy1 |
G |
T |
5: 92,105,831 (GRCm39) |
T39N |
probably benign |
Het |
| Rmi1 |
C |
T |
13: 58,556,840 (GRCm39) |
T363I |
probably benign |
Het |
| Rnpc3 |
A |
C |
3: 113,404,895 (GRCm39) |
I420S |
probably damaging |
Het |
| Rsph4a |
T |
A |
10: 33,785,394 (GRCm39) |
V435E |
probably benign |
Het |
| Rwdd1 |
T |
C |
10: 33,888,095 (GRCm39) |
T38A |
probably damaging |
Het |
| S100a13 |
G |
T |
3: 90,423,170 (GRCm39) |
D54Y |
unknown |
Het |
| Sel1l3 |
T |
C |
5: 53,311,628 (GRCm39) |
Y619C |
probably damaging |
Het |
| Sf3b3 |
T |
C |
8: 111,538,658 (GRCm39) |
T1121A |
probably damaging |
Het |
| Sgk3 |
T |
C |
1: 9,942,534 (GRCm39) |
V102A |
probably benign |
Het |
| Sh2b1 |
T |
C |
7: 126,068,354 (GRCm39) |
T486A |
probably damaging |
Het |
| Slc22a5 |
C |
T |
11: 53,766,981 (GRCm39) |
R169H |
probably damaging |
Het |
| Slc4a5 |
T |
C |
6: 83,266,223 (GRCm39) |
V889A |
possibly damaging |
Het |
| Spast |
C |
A |
17: 74,646,069 (GRCm39) |
S13* |
probably null |
Het |
| Srek1 |
T |
C |
13: 103,889,654 (GRCm39) |
|
probably null |
Het |
| Sugp1 |
G |
T |
8: 70,509,220 (GRCm39) |
E164D |
probably benign |
Het |
| Synpo2 |
T |
C |
3: 122,910,973 (GRCm39) |
D224G |
probably benign |
Het |
| Tanc1 |
A |
G |
2: 59,630,432 (GRCm39) |
D804G |
probably damaging |
Het |
| Tep1 |
C |
T |
14: 51,081,766 (GRCm39) |
C1228Y |
probably damaging |
Het |
| Tes |
T |
A |
6: 17,100,341 (GRCm39) |
C325S |
probably benign |
Het |
| Themis |
T |
C |
10: 28,739,390 (GRCm39) |
V620A |
probably benign |
Het |
| Trim17 |
T |
C |
11: 58,862,257 (GRCm39) |
S430P |
probably damaging |
Het |
| Tubgcp5 |
T |
C |
7: 55,445,693 (GRCm39) |
I65T |
possibly damaging |
Het |
| Unc13b |
T |
C |
4: 43,171,955 (GRCm39) |
S928P |
unknown |
Het |
| Vat1l |
C |
T |
8: 115,016,172 (GRCm39) |
A354V |
probably damaging |
Het |
| Vmn1r170 |
T |
A |
7: 23,306,263 (GRCm39) |
S222T |
probably benign |
Het |
| Vmn2r112 |
A |
T |
17: 22,820,213 (GRCm39) |
M29L |
probably benign |
Het |
| Vmn2r72 |
T |
C |
7: 85,400,411 (GRCm39) |
I213V |
probably benign |
Het |
| Wdr89 |
T |
A |
12: 75,679,564 (GRCm39) |
Q230L |
possibly damaging |
Het |
| Zfp386 |
A |
G |
12: 116,023,283 (GRCm39) |
T334A |
probably benign |
Het |
| Zfp442 |
T |
A |
2: 150,251,287 (GRCm39) |
H205L |
probably benign |
Het |
| Zfyve26 |
A |
T |
12: 79,323,076 (GRCm39) |
I890N |
possibly damaging |
Het |
| Zic1 |
T |
C |
9: 91,246,373 (GRCm39) |
E233G |
probably damaging |
Het |
|
| Other mutations in Col15a1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01154:Col15a1
|
APN |
4 |
47,208,450 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL01561:Col15a1
|
APN |
4 |
47,312,118 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01750:Col15a1
|
APN |
4 |
47,303,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02112:Col15a1
|
APN |
4 |
47,253,985 (GRCm39) |
splice site |
probably benign |
|
|
IGL02158:Col15a1
|
APN |
4 |
47,300,606 (GRCm39) |
splice site |
probably null |
|
|
IGL02268:Col15a1
|
APN |
4 |
47,245,380 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02325:Col15a1
|
APN |
4 |
47,289,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02583:Col15a1
|
APN |
4 |
47,279,866 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02699:Col15a1
|
APN |
4 |
47,284,471 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03167:Col15a1
|
APN |
4 |
47,282,635 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03174:Col15a1
|
APN |
4 |
47,282,666 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0119:Col15a1
|
UTSW |
4 |
47,262,950 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0299:Col15a1
|
UTSW |
4 |
47,262,950 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0499:Col15a1
|
UTSW |
4 |
47,262,950 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0567:Col15a1
|
UTSW |
4 |
47,293,231 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0607:Col15a1
|
UTSW |
4 |
47,282,654 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0992:Col15a1
|
UTSW |
4 |
47,300,491 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1165:Col15a1
|
UTSW |
4 |
47,257,275 (GRCm39) |
splice site |
probably benign |
|
|
R1191:Col15a1
|
UTSW |
4 |
47,254,083 (GRCm39) |
nonsense |
probably null |
|
|
R1852:Col15a1
|
UTSW |
4 |
47,299,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2349:Col15a1
|
UTSW |
4 |
47,306,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2512:Col15a1
|
UTSW |
4 |
47,245,868 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R2517:Col15a1
|
UTSW |
4 |
47,208,492 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2895:Col15a1
|
UTSW |
4 |
47,312,091 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R3688:Col15a1
|
UTSW |
4 |
47,258,689 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3848:Col15a1
|
UTSW |
4 |
47,289,374 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4430:Col15a1
|
UTSW |
4 |
47,245,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4587:Col15a1
|
UTSW |
4 |
47,257,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4793:Col15a1
|
UTSW |
4 |
47,262,997 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4812:Col15a1
|
UTSW |
4 |
47,262,479 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4922:Col15a1
|
UTSW |
4 |
47,258,719 (GRCm39) |
missense |
probably benign |
|
|
R5233:Col15a1
|
UTSW |
4 |
47,296,112 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R5602:Col15a1
|
UTSW |
4 |
47,312,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5786:Col15a1
|
UTSW |
4 |
47,280,865 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R5910:Col15a1
|
UTSW |
4 |
47,289,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5921:Col15a1
|
UTSW |
4 |
47,300,602 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5974:Col15a1
|
UTSW |
4 |
47,258,683 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5985:Col15a1
|
UTSW |
4 |
47,284,507 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6010:Col15a1
|
UTSW |
4 |
47,245,630 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6720:Col15a1
|
UTSW |
4 |
47,247,552 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6791:Col15a1
|
UTSW |
4 |
47,300,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6855:Col15a1
|
UTSW |
4 |
47,245,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6965:Col15a1
|
UTSW |
4 |
47,247,533 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7201:Col15a1
|
UTSW |
4 |
47,307,752 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7261:Col15a1
|
UTSW |
4 |
47,269,088 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7273:Col15a1
|
UTSW |
4 |
47,284,467 (GRCm39) |
splice site |
probably null |
|
|
R7413:Col15a1
|
UTSW |
4 |
47,245,431 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7658:Col15a1
|
UTSW |
4 |
47,245,591 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8032:Col15a1
|
UTSW |
4 |
47,288,108 (GRCm39) |
missense |
unknown |
|
|
R8075:Col15a1
|
UTSW |
4 |
47,208,359 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8130:Col15a1
|
UTSW |
4 |
47,312,196 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8536:Col15a1
|
UTSW |
4 |
47,208,536 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8873:Col15a1
|
UTSW |
4 |
47,247,552 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8887:Col15a1
|
UTSW |
4 |
47,287,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9141:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9143:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9161:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9176:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9177:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9181:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9184:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9185:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9214:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9268:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9362:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9367:Col15a1
|
UTSW |
4 |
47,245,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9385:Col15a1
|
UTSW |
4 |
47,300,473 (GRCm39) |
nonsense |
probably null |
|
|
R9391:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9392:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9419:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9421:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9422:Col15a1
|
UTSW |
4 |
47,293,364 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9426:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9427:Col15a1
|
UTSW |
4 |
47,288,200 (GRCm39) |
unclassified |
probably benign |
|
|
R9429:Col15a1
|
UTSW |
4 |
47,310,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9646:Col15a1
|
UTSW |
4 |
47,257,187 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9747:Col15a1
|
UTSW |
4 |
47,312,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Col15a1
|
UTSW |
4 |
47,245,807 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCCCTGAAGAGTCTAAAAGGAGC -3'
(R):5'- AGGTACAGTTGCTGTGAGAGC -3'
Sequencing Primer
(F):5'- TCTAAAAGGAGCATCTTTGAGAGGAC -3'
(R):5'- TGGCTGTCCCAGACACTTAAAGTG -3'
|
| Posted On |
2022-03-25 |
Incidental Mutation