Mutagenetix > Incidental Mutation

Incidental Mutation 'R9269:Tep1'

702796

Institutional Source

Beutler Lab

Gene Symbol

Tep1

Ensembl Gene

ENSMUSG00000006281

Gene Name

telomerase associated protein 1

Synonyms

Tp1

MMRRC Submission

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R9269 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

51061516-51108017 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 51081766 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Tyrosine at position 1228 (C1228Y)

Ref Sequence

ENSEMBL: ENSMUSP00000006444 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000006444]

AlphaFold

P97499

Predicted Effect

probably damaging
Transcript: ENSMUST00000006444
AA Change: C1228Y

PolyPhen 2 Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000006444
Gene: ENSMUSG00000006281
AA Change: C1228Y

Domain	Start	End	E-Value	Type
Pfam:TEP1_N	1	29	2.8e-20	PFAM
Pfam:TEP1_N	31	59	1.4e-20	PFAM
Pfam:TEP1_N	61	89	3.1e-20	PFAM
Pfam:TEP1_N	91	119	3e-20	PFAM
low complexity region	195	207	N/A	INTRINSIC
low complexity region	211	229	N/A	INTRINSIC
Pfam:TROVE	230	685	3.2e-136	PFAM
Pfam:DUF4062	909	1020	2.4e-22	PFAM
Pfam:NACHT	1171	1346	9.2e-38	PFAM
low complexity region	1393	1405	N/A	INTRINSIC
low complexity region	1622	1641	N/A	INTRINSIC
WD40	1673	1711	2.98e-1	SMART
WD40	1714	1752	5.33e0	SMART
WD40	1755	1794	1.52e-4	SMART
WD40	1797	1835	3.27e-4	SMART
WD40	1838	1877	3.09e-1	SMART
WD40	1880	1919	2.24e-2	SMART
WD40	1925	1962	4.95e0	SMART
WD40	1968	2003	2.29e1	SMART
WD40	2008	2045	1.72e0	SMART
WD40	2058	2097	3.89e-11	SMART
WD40	2103	2142	3.93e-7	SMART
WD40	2145	2182	4.38e-5	SMART
WD40	2184	2232	1.24e0	SMART
WD40	2235	2273	1.14e-3	SMART
WD40	2275	2315	4.46e-1	SMART
Blast:WD40	2316	2353	4e-12	BLAST
WD40	2546	2583	6.79e-2	SMART

Predicted Effect

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.6%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
PHENOTYPE: Mice homozygous for a disruption in this gene show no obvious phenotype. No changes are seen in telomerase activity or telomere length. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 90 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2m	T	C	6: 121,637,865 (GRCm39)	S845P	probably benign	Het
Actn1	T	A	12: 80,219,745 (GRCm39)	N709Y	probably benign	Het
Alox5ap	A	G	5: 149,216,006 (GRCm39)	Y64C	probably damaging	Het
Anapc4	T	A	5: 53,018,620 (GRCm39)	S521T	possibly damaging	Het
Ap3b1	C	A	13: 94,540,570 (GRCm39)	P164Q	probably damaging	Het
Arhgef26	A	G	3: 62,247,920 (GRCm39)	N335D	probably damaging	Het
Arrdc2	G	A	8: 71,288,973 (GRCm39)	A354V	probably benign	Het
Atg2b	A	G	12: 105,618,359 (GRCm39)	S898P	probably damaging	Het
Atxn1	T	A	13: 45,710,680 (GRCm39)	T751S	probably benign	Het
Begain	T	A	12: 108,999,119 (GRCm39)	R551W	possibly damaging	Het
Borcs8	C	A	8: 70,594,521 (GRCm39)	D15E	probably benign	Het
Btbd16	C	T	7: 130,417,516 (GRCm39)	R344C	probably damaging	Het
Card11	A	T	5: 140,892,516 (GRCm39)	M183K	probably damaging	Het
Cldn3	T	C	5: 135,015,579 (GRCm39)	L94P	probably damaging	Het
Clvs2	A	T	10: 33,419,422 (GRCm39)	Y211N	probably damaging	Het
Col15a1	G	C	4: 47,288,200 (GRCm39)		probably benign	Het
Cop1	C	T	1: 159,116,553 (GRCm39)	P409L	probably benign	Het
Cplane1	A	C	15: 8,248,500 (GRCm39)	Q1683P	probably damaging	Het
Crhbp	C	A	13: 95,573,024 (GRCm39)	A241S	probably benign	Het
Cyfip1	C	A	7: 55,557,179 (GRCm39)	S794*	probably null	Het
Dlg5	T	A	14: 24,242,881 (GRCm39)	H172L	probably damaging	Het
Doc2a	T	A	7: 126,450,159 (GRCm39)	I199N	probably benign	Het
Dock3	T	C	9: 106,818,522 (GRCm39)	T1191A	probably benign	Het
Efcab8	G	C	2: 153,646,861 (GRCm39)	V397L	unknown	Het
Eif4a3l2	C	T	6: 116,529,317 (GRCm39)	T398I	probably damaging	Het
Fcgr1	C	T	3: 96,193,154 (GRCm39)	R281H	probably benign	Het
Fndc10	T	C	4: 155,779,205 (GRCm39)	V83A	possibly damaging	Het
Galnt2	T	A	8: 125,065,202 (GRCm39)	I444K	probably benign	Het
Gcnt3	T	C	9: 69,941,290 (GRCm39)	Y426C	probably damaging	Het
Gtpbp1	C	T	15: 79,601,855 (GRCm39)	R533C	probably damaging	Het
Hid1	T	C	11: 115,252,502 (GRCm39)	E60G	probably damaging	Het
Ighv1-81	A	T	12: 115,884,161 (GRCm39)	L30Q	possibly damaging	Het
Ighv5-8	TATATATATATATATATATATA	TATATATATATATATATATATATA	12: 113,618,565 (GRCm39)		probably null	Het
Ilrun	A	C	17: 28,005,049 (GRCm39)	Y169*	probably null	Het
Klf10	A	G	15: 38,298,002 (GRCm39)	L44P	probably damaging	Het
Lamc3	T	C	2: 31,813,017 (GRCm39)	V1001A	probably benign	Het
Lamc3	C	A	2: 31,818,908 (GRCm39)	S1211*	probably null	Het
Lmx1a	T	A	1: 167,658,194 (GRCm39)	H192Q	probably benign	Het
Nkx2-4	T	C	2: 146,926,184 (GRCm39)	H226R	possibly damaging	Het
Or2d2	T	C	7: 106,727,833 (GRCm39)	I256V	probably benign	Het
Or4a68	T	A	2: 89,270,276 (GRCm39)	M116L	probably damaging	Het
Or4k37	T	C	2: 111,159,297 (GRCm39)	F178L	probably damaging	Het
Or4p18	G	A	2: 88,232,586 (GRCm39)	R231C	probably benign	Het
Or5b101	T	C	19: 13,004,994 (GRCm39)	H233R	probably benign	Het
Or5b114-ps1	A	T	19: 13,353,004 (GRCm39)	N226I	unknown	Het
Or5p52	T	A	7: 107,502,527 (GRCm39)	I201N	possibly damaging	Het
Or7e175	T	C	9: 20,048,757 (GRCm39)	M115T	probably damaging	Het
Or8k1	T	C	2: 86,047,247 (GRCm39)	H269R	probably damaging	Het
Orai3	G	T	7: 127,373,194 (GRCm39)	A232S	probably benign	Het
Pak1ip1	G	A	13: 41,162,727 (GRCm39)	G177R	probably benign	Het
Pcp4l1	T	C	1: 171,001,975 (GRCm39)	R62G	possibly damaging	Het
Phox2b	T	A	5: 67,256,064 (GRCm39)	Q74L	probably benign	Het
Pi4kb	A	G	3: 94,891,797 (GRCm39)	Y159C	probably damaging	Het
Pkd1l3	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	8: 110,350,827 (GRCm39)		probably benign	Het
Plxna1	T	C	6: 89,306,541 (GRCm39)	R1430G	probably null	Het
Plxna4	T	C	6: 32,155,315 (GRCm39)	H1543R	probably benign	Het
Prcc	A	T	3: 87,777,038 (GRCm39)	F312Y	probably damaging	Het
Ranbp6	A	G	19: 29,787,388 (GRCm39)	L988P	probably damaging	Het
Rbm27	A	G	18: 42,460,572 (GRCm39)	T840A	probably benign	Het
Rchy1	G	T	5: 92,105,831 (GRCm39)	T39N	probably benign	Het
Rmi1	C	T	13: 58,556,840 (GRCm39)	T363I	probably benign	Het
Rnpc3	A	C	3: 113,404,895 (GRCm39)	I420S	probably damaging	Het
Rsph4a	T	A	10: 33,785,394 (GRCm39)	V435E	probably benign	Het
Rwdd1	T	C	10: 33,888,095 (GRCm39)	T38A	probably damaging	Het
S100a13	G	T	3: 90,423,170 (GRCm39)	D54Y	unknown	Het
Sel1l3	T	C	5: 53,311,628 (GRCm39)	Y619C	probably damaging	Het
Sf3b3	T	C	8: 111,538,658 (GRCm39)	T1121A	probably damaging	Het
Sgk3	T	C	1: 9,942,534 (GRCm39)	V102A	probably benign	Het
Sh2b1	T	C	7: 126,068,354 (GRCm39)	T486A	probably damaging	Het
Slc22a5	C	T	11: 53,766,981 (GRCm39)	R169H	probably damaging	Het
Slc4a5	T	C	6: 83,266,223 (GRCm39)	V889A	possibly damaging	Het
Spast	C	A	17: 74,646,069 (GRCm39)	S13*	probably null	Het
Srek1	T	C	13: 103,889,654 (GRCm39)		probably null	Het
Sugp1	G	T	8: 70,509,220 (GRCm39)	E164D	probably benign	Het
Synpo2	T	C	3: 122,910,973 (GRCm39)	D224G	probably benign	Het
Tanc1	A	G	2: 59,630,432 (GRCm39)	D804G	probably damaging	Het
Tes	T	A	6: 17,100,341 (GRCm39)	C325S	probably benign	Het
Themis	T	C	10: 28,739,390 (GRCm39)	V620A	probably benign	Het
Trim17	T	C	11: 58,862,257 (GRCm39)	S430P	probably damaging	Het
Tubgcp5	T	C	7: 55,445,693 (GRCm39)	I65T	possibly damaging	Het
Unc13b	T	C	4: 43,171,955 (GRCm39)	S928P	unknown	Het
Vat1l	C	T	8: 115,016,172 (GRCm39)	A354V	probably damaging	Het
Vmn1r170	T	A	7: 23,306,263 (GRCm39)	S222T	probably benign	Het
Vmn2r112	A	T	17: 22,820,213 (GRCm39)	M29L	probably benign	Het
Vmn2r72	T	C	7: 85,400,411 (GRCm39)	I213V	probably benign	Het
Wdr89	T	A	12: 75,679,564 (GRCm39)	Q230L	possibly damaging	Het
Zfp386	A	G	12: 116,023,283 (GRCm39)	T334A	probably benign	Het
Zfp442	T	A	2: 150,251,287 (GRCm39)	H205L	probably benign	Het
Zfyve26	A	T	12: 79,323,076 (GRCm39)	I890N	possibly damaging	Het
Zic1	T	C	9: 91,246,373 (GRCm39)	E233G	probably damaging	Het

Other mutations in Tep1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00482:Tep1	APN	14	51,080,641 (GRCm39)	missense	probably damaging	1.00
IGL00490:Tep1	APN	14	51,070,930 (GRCm39)	missense	probably damaging	0.97
IGL01114:Tep1	APN	14	51,088,096 (GRCm39)	missense	probably damaging	0.98
IGL01294:Tep1	APN	14	51,067,114 (GRCm39)	splice site	probably benign
IGL01902:Tep1	APN	14	51,103,548 (GRCm39)	splice site	probably benign
IGL01910:Tep1	APN	14	51,081,569 (GRCm39)	missense	probably benign	0.06
IGL01925:Tep1	APN	14	51,061,955 (GRCm39)	unclassified	probably benign
IGL01965:Tep1	APN	14	51,100,952 (GRCm39)	splice site	probably benign
IGL02071:Tep1	APN	14	51,071,506 (GRCm39)	missense	possibly damaging	0.93
IGL02124:Tep1	APN	14	51,091,581 (GRCm39)	unclassified	probably benign
IGL02189:Tep1	APN	14	51,064,283 (GRCm39)	missense	probably benign
IGL02252:Tep1	APN	14	51,067,712 (GRCm39)	missense	possibly damaging	0.93
IGL02299:Tep1	APN	14	51,078,128 (GRCm39)	missense	probably damaging	0.99
IGL02343:Tep1	APN	14	51,066,704 (GRCm39)	missense	probably damaging	0.99
IGL02423:Tep1	APN	14	51,082,077 (GRCm39)	missense	possibly damaging	0.53
IGL02537:Tep1	APN	14	51,073,570 (GRCm39)	missense	probably damaging	0.96
IGL02601:Tep1	APN	14	51,070,935 (GRCm39)	nonsense	probably null
IGL02941:Tep1	APN	14	51,103,494 (GRCm39)	missense	probably damaging	0.98
IGL02990:Tep1	APN	14	51,105,703 (GRCm39)	missense	possibly damaging	0.86
IGL03144:Tep1	APN	14	51,081,474 (GRCm39)	splice site	probably benign
IGL03209:Tep1	APN	14	51,078,160 (GRCm39)	splice site	probably benign
R0240_Tep1_347	UTSW	14	51,100,486 (GRCm39)	splice site	probably benign
R0972_Tep1_893	UTSW	14	51,061,753 (GRCm39)	unclassified	probably benign
R1686_Tep1_375	UTSW	14	51,074,245 (GRCm39)	missense	probably benign	0.12
R7232_Tep1_671	UTSW	14	51,081,789 (GRCm39)	missense	unknown
R8009_Tep1_822	UTSW	14	51,061,687 (GRCm39)	missense	possibly damaging	0.93
PIT4305001:Tep1	UTSW	14	51,066,684 (GRCm39)	missense	possibly damaging	0.90
PIT4362001:Tep1	UTSW	14	51,103,510 (GRCm39)	missense	probably benign	0.23
R0058:Tep1	UTSW	14	51,071,522 (GRCm39)	missense	possibly damaging	0.85
R0060:Tep1	UTSW	14	51,103,486 (GRCm39)	missense	probably damaging	1.00
R0109:Tep1	UTSW	14	51,089,373 (GRCm39)	splice site	probably null
R0123:Tep1	UTSW	14	51,067,150 (GRCm39)	missense	possibly damaging	0.84
R0134:Tep1	UTSW	14	51,067,150 (GRCm39)	missense	possibly damaging	0.84
R0148:Tep1	UTSW	14	51,062,246 (GRCm39)	missense	possibly damaging	0.70
R0240:Tep1	UTSW	14	51,100,486 (GRCm39)	splice site	probably benign
R0243:Tep1	UTSW	14	51,084,444 (GRCm39)	missense	probably damaging	1.00
R0373:Tep1	UTSW	14	51,074,225 (GRCm39)	missense	possibly damaging	0.85
R0432:Tep1	UTSW	14	51,104,280 (GRCm39)	small deletion	probably benign
R0464:Tep1	UTSW	14	51,085,141 (GRCm39)	missense	probably benign	0.00
R0566:Tep1	UTSW	14	51,082,871 (GRCm39)	critical splice donor site	probably null
R0691:Tep1	UTSW	14	51,104,301 (GRCm39)	nonsense	probably null
R0787:Tep1	UTSW	14	51,066,687 (GRCm39)	missense	possibly damaging	0.85
R0972:Tep1	UTSW	14	51,061,753 (GRCm39)	unclassified	probably benign
R1263:Tep1	UTSW	14	51,082,970 (GRCm39)	missense	possibly damaging	0.84
R1300:Tep1	UTSW	14	51,064,512 (GRCm39)	critical splice donor site	probably null
R1327:Tep1	UTSW	14	51,090,556 (GRCm39)	missense	probably benign	0.18
R1556:Tep1	UTSW	14	51,090,499 (GRCm39)	missense	probably benign	0.06
R1584:Tep1	UTSW	14	51,103,494 (GRCm39)	missense	probably damaging	0.98
R1607:Tep1	UTSW	14	51,062,020 (GRCm39)	missense	probably null	0.99
R1686:Tep1	UTSW	14	51,074,245 (GRCm39)	missense	probably benign	0.12
R1715:Tep1	UTSW	14	51,092,024 (GRCm39)	missense	possibly damaging	0.92
R1778:Tep1	UTSW	14	51,067,079 (GRCm39)	intron	probably benign
R1993:Tep1	UTSW	14	51,061,641 (GRCm39)	missense	possibly damaging	0.93
R2071:Tep1	UTSW	14	51,091,739 (GRCm39)	missense	probably benign	0.23
R2104:Tep1	UTSW	14	51,088,037 (GRCm39)	splice site	probably benign
R2118:Tep1	UTSW	14	51,093,029 (GRCm39)	splice site	probably null
R2119:Tep1	UTSW	14	51,076,443 (GRCm39)	missense	probably benign	0.13
R2208:Tep1	UTSW	14	51,104,321 (GRCm39)	missense	probably benign	0.01
R2241:Tep1	UTSW	14	51,091,667 (GRCm39)	missense	probably benign	0.01
R2243:Tep1	UTSW	14	51,091,667 (GRCm39)	missense	probably benign	0.01
R2311:Tep1	UTSW	14	51,071,024 (GRCm39)	missense	possibly damaging	0.95
R2420:Tep1	UTSW	14	51,071,480 (GRCm39)	missense	probably benign
R2874:Tep1	UTSW	14	51,088,107 (GRCm39)	missense	possibly damaging	0.71
R3084:Tep1	UTSW	14	51,064,511 (GRCm39)	critical splice donor site	probably null
R3086:Tep1	UTSW	14	51,064,511 (GRCm39)	critical splice donor site	probably null
R3621:Tep1	UTSW	14	51,066,477 (GRCm39)	missense	probably damaging	0.99
R3815:Tep1	UTSW	14	51,105,772 (GRCm39)	missense	possibly damaging	0.71
R4124:Tep1	UTSW	14	51,081,191 (GRCm39)	missense	possibly damaging	0.93
R4125:Tep1	UTSW	14	51,081,191 (GRCm39)	missense	possibly damaging	0.93
R4127:Tep1	UTSW	14	51,081,191 (GRCm39)	missense	possibly damaging	0.93
R4134:Tep1	UTSW	14	51,082,317 (GRCm39)	missense	probably benign
R4152:Tep1	UTSW	14	51,075,051 (GRCm39)	missense	possibly damaging	0.72
R4153:Tep1	UTSW	14	51,075,051 (GRCm39)	missense	possibly damaging	0.72
R4191:Tep1	UTSW	14	51,074,263 (GRCm39)	missense	probably damaging	0.96
R4248:Tep1	UTSW	14	51,100,351 (GRCm39)	missense	possibly damaging	0.93
R4293:Tep1	UTSW	14	51,084,318 (GRCm39)	missense	probably benign
R4569:Tep1	UTSW	14	51,062,197 (GRCm39)	missense	probably benign	0.01
R4704:Tep1	UTSW	14	51,074,530 (GRCm39)	missense	probably benign	0.06
R4815:Tep1	UTSW	14	51,078,759 (GRCm39)	missense	probably damaging	0.99
R4978:Tep1	UTSW	14	51,082,891 (GRCm39)	missense	possibly damaging	0.93
R4989:Tep1	UTSW	14	51,076,457 (GRCm39)	missense	probably benign
R5022:Tep1	UTSW	14	51,066,456 (GRCm39)	missense	probably benign	0.27
R5057:Tep1	UTSW	14	51,066,456 (GRCm39)	missense	probably benign	0.27
R5063:Tep1	UTSW	14	51,088,084 (GRCm39)	missense	possibly damaging	0.86
R5118:Tep1	UTSW	14	51,093,044 (GRCm39)	splice site	probably null
R5128:Tep1	UTSW	14	51,081,736 (GRCm39)	makesense	probably null
R5149:Tep1	UTSW	14	51,074,855 (GRCm39)	nonsense	probably null
R5171:Tep1	UTSW	14	51,062,259 (GRCm39)	missense	probably benign	0.01
R5201:Tep1	UTSW	14	51,105,567 (GRCm39)	missense	probably benign	0.01
R5260:Tep1	UTSW	14	51,076,088 (GRCm39)	missense	probably benign
R5339:Tep1	UTSW	14	51,082,031 (GRCm39)	missense	probably damaging	0.99
R5384:Tep1	UTSW	14	51,105,774 (GRCm39)	missense	probably damaging	0.98
R5385:Tep1	UTSW	14	51,105,774 (GRCm39)	missense	probably damaging	0.98
R5386:Tep1	UTSW	14	51,105,774 (GRCm39)	missense	probably damaging	0.98
R5594:Tep1	UTSW	14	51,067,339 (GRCm39)	missense	possibly damaging	0.86
R5639:Tep1	UTSW	14	51,091,062 (GRCm39)	missense	possibly damaging	0.85
R5749:Tep1	UTSW	14	51,081,529 (GRCm39)	missense	possibly damaging	0.59
R5756:Tep1	UTSW	14	51,074,836 (GRCm39)	critical splice donor site	probably null
R6013:Tep1	UTSW	14	51,098,505 (GRCm39)	missense	probably damaging	0.97
R6014:Tep1	UTSW	14	51,084,457 (GRCm39)	missense	probably benign	0.12
R6248:Tep1	UTSW	14	51,067,715 (GRCm39)	missense	probably damaging	0.98
R6264:Tep1	UTSW	14	51,082,970 (GRCm39)	missense	probably damaging	0.99
R6363:Tep1	UTSW	14	51,062,005 (GRCm39)	missense	probably benign	0.04
R6381:Tep1	UTSW	14	51,082,888 (GRCm39)	missense	probably damaging	0.99
R6462:Tep1	UTSW	14	51,081,836 (GRCm39)	missense	probably benign
R6942:Tep1	UTSW	14	51,074,194 (GRCm39)	missense	possibly damaging	0.85
R6951:Tep1	UTSW	14	51,071,370 (GRCm39)	critical splice donor site	probably null
R6979:Tep1	UTSW	14	51,076,094 (GRCm39)	missense	possibly damaging	0.93
R6999:Tep1	UTSW	14	51,088,162 (GRCm39)	missense	possibly damaging	0.86
R7099:Tep1	UTSW	14	51,081,944 (GRCm39)	splice site	probably null
R7208:Tep1	UTSW	14	51,062,013 (GRCm39)	critical splice acceptor site	probably null
R7232:Tep1	UTSW	14	51,081,789 (GRCm39)	missense	unknown
R7249:Tep1	UTSW	14	51,061,732 (GRCm39)	missense	possibly damaging	0.86
R7325:Tep1	UTSW	14	51,103,495 (GRCm39)	missense	probably damaging	0.99
R7409:Tep1	UTSW	14	51,104,312 (GRCm39)	missense	possibly damaging	0.67
R7499:Tep1	UTSW	14	51,091,047 (GRCm39)	missense	probably damaging	0.99
R7542:Tep1	UTSW	14	51,099,948 (GRCm39)	nonsense	probably null
R7806:Tep1	UTSW	14	51,074,266 (GRCm39)	missense	possibly damaging	0.85
R7825:Tep1	UTSW	14	51,081,344 (GRCm39)	critical splice acceptor site	probably null
R7901:Tep1	UTSW	14	51,064,308 (GRCm39)	missense	possibly damaging	0.88
R7961:Tep1	UTSW	14	51,061,687 (GRCm39)	missense	possibly damaging	0.93
R7993:Tep1	UTSW	14	51,067,710 (GRCm39)	missense	probably benign	0.41
R8009:Tep1	UTSW	14	51,061,687 (GRCm39)	missense	possibly damaging	0.93
R8085:Tep1	UTSW	14	51,066,753 (GRCm39)	missense	probably benign	0.11
R8299:Tep1	UTSW	14	51,105,502 (GRCm39)	missense	probably benign	0.06
R8330:Tep1	UTSW	14	51,085,162 (GRCm39)	missense	possibly damaging	0.86
R8396:Tep1	UTSW	14	51,074,529 (GRCm39)	missense	probably benign	0.23
R8475:Tep1	UTSW	14	51,078,712 (GRCm39)	missense	probably damaging	1.00
R8695:Tep1	UTSW	14	51,082,894 (GRCm39)	missense	possibly damaging	0.85
R8726:Tep1	UTSW	14	51,085,080 (GRCm39)	missense	probably damaging	0.98
R8812:Tep1	UTSW	14	51,074,589 (GRCm39)	missense	probably damaging	0.98
R9152:Tep1	UTSW	14	51,104,162 (GRCm39)	missense	probably benign	0.14
R9299:Tep1	UTSW	14	51,081,988 (GRCm39)	splice site	probably benign
R9365:Tep1	UTSW	14	51,064,597 (GRCm39)	missense	probably damaging	1.00
R9398:Tep1	UTSW	14	51,066,429 (GRCm39)	missense	possibly damaging	0.85
R9408:Tep1	UTSW	14	51,074,637 (GRCm39)	missense	possibly damaging	0.85
R9445:Tep1	UTSW	14	51,082,967 (GRCm39)	missense	possibly damaging	0.95
R9487:Tep1	UTSW	14	51,066,687 (GRCm39)	missense	possibly damaging	0.93
R9555:Tep1	UTSW	14	51,105,888 (GRCm39)	missense	possibly damaging	0.52
R9597:Tep1	UTSW	14	51,100,465 (GRCm39)	missense	probably damaging	0.99
R9715:Tep1	UTSW	14	51,081,759 (GRCm39)	missense
R9732:Tep1	UTSW	14	51,088,162 (GRCm39)	missense	probably benign	0.33
R9777:Tep1	UTSW	14	51,076,443 (GRCm39)	nonsense	probably null
RF007:Tep1	UTSW	14	51,098,402 (GRCm39)	missense	possibly damaging	0.92
X0024:Tep1	UTSW	14	51,064,576 (GRCm39)	missense	possibly damaging	0.86
X0060:Tep1	UTSW	14	51,074,221 (GRCm39)	missense	probably benign	0.25
Z1177:Tep1	UTSW	14	51,085,222 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- TGCCCCATCGATGATAAGGAC -3'
(R):5'- TCCGGGAGATTATGCACATAC -3'

Sequencing Primer
(F):5'- CTGCAGCGACTGAGCGAATTTG -3'
(R):5'- GGAGATTATGCACATACTGAAATGC -3'

Posted On

2022-03-25