Mutagenetix > Incidental Mutation

Incidental Mutation 'R9269:2410089E03Rik'

702797

Institutional Source

Beutler Lab

Gene Symbol

2410089E03Rik

Ensembl Gene

ENSMUSG00000039801

Gene Name

RIKEN cDNA 2410089E03 gene

Synonyms

b2b012Clo

MMRRC Submission

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R9269 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

8169106-8271158 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 8219016 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Proline at position 1683 (Q1683P)

Ref Sequence

ENSEMBL: ENSMUSP00000106247 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000110617] [ENSMUST00000228039]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000110617
AA Change: Q1683P

PolyPhen 2 Score 0.972 (Sensitivity: 0.77; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000106247
Gene: ENSMUSG00000039801
AA Change: Q1683P

Domain	Start	End	E-Value	Type
low complexity region	144	157	N/A	INTRINSIC
low complexity region	338	352	N/A	INTRINSIC
low complexity region	466	476	N/A	INTRINSIC
low complexity region	868	883	N/A	INTRINSIC
low complexity region	949	962	N/A	INTRINSIC
low complexity region	1400	1415	N/A	INTRINSIC
low complexity region	1449	1464	N/A	INTRINSIC
low complexity region	1827	1838	N/A	INTRINSIC
low complexity region	1919	1930	N/A	INTRINSIC
low complexity region	2130	2145	N/A	INTRINSIC
coiled coil region	2750	2782	N/A	INTRINSIC
low complexity region	2838	2850	N/A	INTRINSIC
Pfam:Joubert	2894	3207	1.9e-136	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000228039

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.6%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene has putative coiled-coil domains and may be a transmembrane protein. Defects in this gene are a cause of Joubert syndrome (JBTS). [provided by RefSeq, May 2012]
PHENOTYPE: Homozygotes exhibit double outlet right ventricle {SDD}, pulmonary atresia/hypolastic pulmonary artery, atrioventricular septal defect, and right aortic arch. Non-cardiovascular defects include cleft palate, polydactyly, transparent chest wall (sternal bone hypoplasia) and hypoplastic lungs. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 90 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2m	T	C	6: 121,660,906 (GRCm38)	S845P	probably benign	Het
Actn1	T	A	12: 80,172,971 (GRCm38)	N709Y	probably benign	Het
Alox5ap	A	G	5: 149,279,196 (GRCm38)	Y64C	probably damaging	Het
Anapc4	T	A	5: 52,861,278 (GRCm38)	S521T	possibly damaging	Het
Ap3b1	C	A	13: 94,404,062 (GRCm38)	P164Q	probably damaging	Het
Arhgef26	A	G	3: 62,340,499 (GRCm38)	N335D	probably damaging	Het
Arrdc2	G	A	8: 70,836,329 (GRCm38)	A354V	probably benign	Het
Atg2b	A	G	12: 105,652,100 (GRCm38)	S898P	probably damaging	Het
Atxn1	T	A	13: 45,557,204 (GRCm38)	T751S	probably benign	Het
Begain	T	A	12: 109,033,193 (GRCm38)	R551W	possibly damaging	Het
Borcs8	C	A	8: 70,141,871 (GRCm38)	D15E	probably benign	Het
Btbd16	C	T	7: 130,815,786 (GRCm38)	R344C	probably damaging	Het
Card11	A	T	5: 140,906,761 (GRCm38)	M183K	probably damaging	Het
Cldn3	T	C	5: 134,986,725 (GRCm38)	L94P	probably damaging	Het
Clvs2	A	T	10: 33,543,426 (GRCm38)	Y211N	probably damaging	Het
Col15a1	G	C	4: 47,288,200 (GRCm38)		probably benign	Het
Cop1	C	T	1: 159,288,983 (GRCm38)	P409L	probably benign	Het
Crhbp	C	A	13: 95,436,516 (GRCm38)	A241S	probably benign	Het
Cyfip1	C	A	7: 55,907,431 (GRCm38)	S794*	probably null	Het
D17Wsu92e	A	C	17: 27,786,075 (GRCm38)	Y169*	probably null	Het
Dlg5	T	A	14: 24,192,813 (GRCm38)	H172L	probably damaging	Het
Doc2a	T	A	7: 126,850,987 (GRCm38)	I199N	probably benign	Het
Dock3	T	C	9: 106,941,323 (GRCm38)	T1191A	probably benign	Het
Efcab8	G	C	2: 153,804,941 (GRCm38)	V397L	unknown	Het
Fcgr1	C	T	3: 96,285,838 (GRCm38)	R281H	probably benign	Het
Fndc10	T	C	4: 155,694,748 (GRCm38)	V83A	possibly damaging	Het
Galnt2	T	A	8: 124,338,463 (GRCm38)	I444K	probably benign	Het
Gcnt3	T	C	9: 70,034,008 (GRCm38)	Y426C	probably damaging	Het
Gm5580	C	T	6: 116,552,356 (GRCm38)	T398I	probably damaging	Het
Gtpbp1	C	T	15: 79,717,654 (GRCm38)	R533C	probably damaging	Het
Hid1	T	C	11: 115,361,676 (GRCm38)	E60G	probably damaging	Het
Ighv1-81	A	T	12: 115,920,541 (GRCm38)	L30Q	possibly damaging	Het
Ighv5-8	TATATATATATATATATATATA	TATATATATATATATATATATATA	12: 113,654,945 (GRCm38)		probably null	Het
Klf10	A	G	15: 38,297,758 (GRCm38)	L44P	probably damaging	Het
Lamc3	T	C	2: 31,923,005 (GRCm38)	V1001A	probably benign	Het
Lamc3	C	A	2: 31,928,896 (GRCm38)	S1211*	probably null	Het
Lmx1a	T	A	1: 167,830,625 (GRCm38)	H192Q	probably benign	Het
Nkx2-4	T	C	2: 147,084,264 (GRCm38)	H226R	possibly damaging	Het
Olfr1046	T	C	2: 86,216,903 (GRCm38)	H269R	probably damaging	Het
Olfr1179	G	A	2: 88,402,242 (GRCm38)	R231C	probably benign	Het
Olfr1240	T	A	2: 89,439,932 (GRCm38)	M116L	probably damaging	Het
Olfr1281	T	C	2: 111,328,952 (GRCm38)	F178L	probably damaging	Het
Olfr1453	T	C	19: 13,027,630 (GRCm38)	H233R	probably benign	Het
Olfr1468-ps1	A	T	19: 13,375,640 (GRCm38)	N226I	unknown	Het
Olfr472	T	A	7: 107,903,320 (GRCm38)	I201N	possibly damaging	Het
Olfr715	T	C	7: 107,128,626 (GRCm38)	I256V	probably benign	Het
Olfr869	T	C	9: 20,137,461 (GRCm38)	M115T	probably damaging	Het
Orai3	G	T	7: 127,774,022 (GRCm38)	A232S	probably benign	Het
Pak1ip1	G	A	13: 41,009,251 (GRCm38)	G177R	probably benign	Het
Pcp4l1	T	C	1: 171,174,406 (GRCm38)	R62G	possibly damaging	Het
Phox2b	T	A	5: 67,098,721 (GRCm38)	Q74L	probably benign	Het
Pi4kb	A	G	3: 94,984,486 (GRCm38)	Y159C	probably damaging	Het
Pkd1l3	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	8: 109,624,195 (GRCm38)		probably benign	Het
Plxna1	T	C	6: 89,329,559 (GRCm38)	R1430G	probably null	Het
Plxna4	T	C	6: 32,178,380 (GRCm38)	H1543R	probably benign	Het
Prcc	A	T	3: 87,869,731 (GRCm38)	F312Y	probably damaging	Het
Ranbp6	A	G	19: 29,809,988 (GRCm38)	L988P	probably damaging	Het
Rbm27	A	G	18: 42,327,507 (GRCm38)	T840A	probably benign	Het
Rchy1	G	T	5: 91,957,972 (GRCm38)	T39N	probably benign	Het
Rmi1	C	T	13: 58,409,026 (GRCm38)	T363I	probably benign	Het
Rnpc3	A	C	3: 113,611,246 (GRCm38)	I420S	probably damaging	Het
Rsph4a	T	A	10: 33,909,398 (GRCm38)	V435E	probably benign	Het
Rwdd1	T	C	10: 34,012,099 (GRCm38)	T38A	probably damaging	Het
S100a13	G	T	3: 90,515,863 (GRCm38)	D54Y	unknown	Het
Sel1l3	T	C	5: 53,154,286 (GRCm38)	Y619C	probably damaging	Het
Sf3b3	T	C	8: 110,812,026 (GRCm38)	T1121A	probably damaging	Het
Sgk3	T	C	1: 9,872,309 (GRCm38)	V102A	probably benign	Het
Sh2b1	T	C	7: 126,469,182 (GRCm38)	T486A	probably damaging	Het
Slc22a5	C	T	11: 53,876,155 (GRCm38)	R169H	probably damaging	Het
Slc4a5	T	C	6: 83,289,241 (GRCm38)	V889A	possibly damaging	Het
Spast	C	A	17: 74,339,074 (GRCm38)	S13*	probably null	Het
Srek1	T	C	13: 103,753,146 (GRCm38)		probably null	Het
Sugp1	G	T	8: 70,056,570 (GRCm38)	E164D	probably benign	Het
Synpo2	T	C	3: 123,117,324 (GRCm38)	D224G	probably benign	Het
Tanc1	A	G	2: 59,800,088 (GRCm38)	D804G	probably damaging	Het
Tep1	C	T	14: 50,844,309 (GRCm38)	C1228Y	probably damaging	Het
Tes	T	A	6: 17,100,342 (GRCm38)	C325S	probably benign	Het
Themis	T	C	10: 28,863,394 (GRCm38)	V620A	probably benign	Het
Trim17	T	C	11: 58,971,431 (GRCm38)	S430P	probably damaging	Het
Tubgcp5	T	C	7: 55,795,945 (GRCm38)	I65T	possibly damaging	Het
Unc13b	T	C	4: 43,171,955 (GRCm38)	S928P	unknown	Het
Vat1l	C	T	8: 114,289,432 (GRCm38)	A354V	probably damaging	Het
Vmn1r170	T	A	7: 23,606,838 (GRCm38)	S222T	probably benign	Het
Vmn2r112	A	T	17: 22,601,232 (GRCm38)	M29L	probably benign	Het
Vmn2r72	T	C	7: 85,751,203 (GRCm38)	I213V	probably benign	Het
Wdr89	T	A	12: 75,632,790 (GRCm38)	Q230L	possibly damaging	Het
Zfp386	A	G	12: 116,059,663 (GRCm38)	T334A	probably benign	Het
Zfp442	T	A	2: 150,409,367 (GRCm38)	H205L	probably benign	Het
Zfyve26	A	T	12: 79,276,302 (GRCm38)	I890N	possibly damaging	Het
Zic1	T	C	9: 91,364,320 (GRCm38)	E233G	probably damaging	Het

Other mutations in 2410089E03Rik

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00756:2410089E03Rik	APN	15	8,264,447 (GRCm38)	splice site	probably benign
IGL00766:2410089E03Rik	APN	15	8,252,164 (GRCm38)	missense	unknown
IGL01483:2410089E03Rik	APN	15	8,187,107 (GRCm38)	missense	probably damaging	0.98
IGL01520:2410089E03Rik	APN	15	8,221,911 (GRCm38)	missense	probably damaging	0.96
IGL01578:2410089E03Rik	APN	15	8,270,710 (GRCm38)	missense	unknown
IGL01701:2410089E03Rik	APN	15	8,203,257 (GRCm38)	splice site	probably benign
IGL01892:2410089E03Rik	APN	15	8,242,265 (GRCm38)	splice site	probably benign
IGL01895:2410089E03Rik	APN	15	8,229,107 (GRCm38)	missense	possibly damaging	0.63
IGL01922:2410089E03Rik	APN	15	8,270,821 (GRCm38)	missense	unknown
IGL01978:2410089E03Rik	APN	15	8,219,382 (GRCm38)	missense	probably damaging	0.98
IGL02031:2410089E03Rik	APN	15	8,179,769 (GRCm38)	missense	probably damaging	0.99
IGL02318:2410089E03Rik	APN	15	8,175,025 (GRCm38)	missense	probably damaging	0.98
IGL02321:2410089E03Rik	APN	15	8,216,572 (GRCm38)	missense	probably benign	0.04
IGL02363:2410089E03Rik	APN	15	8,218,437 (GRCm38)	missense	possibly damaging	0.68
IGL02404:2410089E03Rik	APN	15	8,187,284 (GRCm38)	missense	possibly damaging	0.48
IGL02535:2410089E03Rik	APN	15	8,174,838 (GRCm38)	missense	probably damaging	1.00
IGL02732:2410089E03Rik	APN	15	8,179,891 (GRCm38)	missense	probably benign	0.03
IGL02895:2410089E03Rik	APN	15	8,232,107 (GRCm38)	splice site	probably benign
IGL02903:2410089E03Rik	APN	15	8,269,778 (GRCm38)	missense	unknown
IGL02903:2410089E03Rik	APN	15	8,269,779 (GRCm38)	missense	unknown
IGL02979:2410089E03Rik	APN	15	8,218,554 (GRCm38)	missense	possibly damaging	0.82
IGL03077:2410089E03Rik	APN	15	8,212,795 (GRCm38)	splice site	probably benign
IGL03196:2410089E03Rik	APN	15	8,201,342 (GRCm38)	missense	probably damaging	0.98
IGL03344:2410089E03Rik	APN	15	8,187,458 (GRCm38)	missense	possibly damaging	0.63
IGL03368:2410089E03Rik	APN	15	8,222,373 (GRCm38)	missense	probably benign	0.06
IGL03403:2410089E03Rik	APN	15	8,201,342 (GRCm38)	missense	probably damaging	0.98
agnes	UTSW	15	8,246,938 (GRCm38)	nonsense	probably null
dei	UTSW	15	8,186,165 (GRCm38)	missense	probably damaging	1.00
R0015:2410089E03Rik	UTSW	15	8,186,184 (GRCm38)	missense	probably damaging	1.00
R0015:2410089E03Rik	UTSW	15	8,186,184 (GRCm38)	missense	probably damaging	1.00
R0101:2410089E03Rik	UTSW	15	8,220,960 (GRCm38)	missense	probably benign	0.00
R0105:2410089E03Rik	UTSW	15	8,187,392 (GRCm38)	missense	probably benign
R0105:2410089E03Rik	UTSW	15	8,187,392 (GRCm38)	missense	probably benign
R0165:2410089E03Rik	UTSW	15	8,216,382 (GRCm38)	missense	probably damaging	1.00
R0306:2410089E03Rik	UTSW	15	8,179,889 (GRCm38)	missense	probably damaging	1.00
R0433:2410089E03Rik	UTSW	15	8,216,562 (GRCm38)	missense	probably benign	0.00
R0491:2410089E03Rik	UTSW	15	8,182,243 (GRCm38)	missense	probably damaging	1.00
R0523:2410089E03Rik	UTSW	15	8,194,386 (GRCm38)	missense	probably damaging	1.00
R0571:2410089E03Rik	UTSW	15	8,259,793 (GRCm38)	missense	unknown
R0679:2410089E03Rik	UTSW	15	8,223,122 (GRCm38)	missense	probably benign	0.39
R0704:2410089E03Rik	UTSW	15	8,210,083 (GRCm38)	missense	possibly damaging	0.93
R0707:2410089E03Rik	UTSW	15	8,258,321 (GRCm38)	missense	unknown
R0715:2410089E03Rik	UTSW	15	8,223,092 (GRCm38)	missense	probably benign	0.14
R0762:2410089E03Rik	UTSW	15	8,218,416 (GRCm38)	unclassified	probably benign
R0830:2410089E03Rik	UTSW	15	8,247,185 (GRCm38)	missense	unknown
R0924:2410089E03Rik	UTSW	15	8,251,070 (GRCm38)	splice site	probably benign
R1071:2410089E03Rik	UTSW	15	8,218,426 (GRCm38)	missense	probably benign	0.20
R1184:2410089E03Rik	UTSW	15	8,216,487 (GRCm38)	missense	probably benign
R1224:2410089E03Rik	UTSW	15	8,178,385 (GRCm38)	missense	probably benign	0.06
R1416:2410089E03Rik	UTSW	15	8,246,938 (GRCm38)	nonsense	probably null
R1428:2410089E03Rik	UTSW	15	8,219,369 (GRCm38)	missense	possibly damaging	0.83
R1487:2410089E03Rik	UTSW	15	8,186,231 (GRCm38)	missense	probably damaging	1.00
R1641:2410089E03Rik	UTSW	15	8,228,959 (GRCm38)	missense	probably benign	0.41
R1652:2410089E03Rik	UTSW	15	8,201,146 (GRCm38)	missense	probably damaging	1.00
R1688:2410089E03Rik	UTSW	15	8,228,609 (GRCm38)	missense	probably benign	0.00
R1715:2410089E03Rik	UTSW	15	8,226,900 (GRCm38)	splice site	probably null
R1820:2410089E03Rik	UTSW	15	8,269,645 (GRCm38)	missense	unknown
R1863:2410089E03Rik	UTSW	15	8,228,593 (GRCm38)	missense	probably benign	0.00
R1940:2410089E03Rik	UTSW	15	8,233,852 (GRCm38)	missense	probably damaging	0.98
R1967:2410089E03Rik	UTSW	15	8,203,420 (GRCm38)	missense	probably benign	0.09
R2064:2410089E03Rik	UTSW	15	8,186,165 (GRCm38)	missense	probably damaging	1.00
R2076:2410089E03Rik	UTSW	15	8,219,257 (GRCm38)	missense	possibly damaging	0.93
R2163:2410089E03Rik	UTSW	15	8,203,251 (GRCm38)	splice site	probably null
R2208:2410089E03Rik	UTSW	15	8,194,403 (GRCm38)	missense	probably benign	0.33
R2504:2410089E03Rik	UTSW	15	8,219,216 (GRCm38)	missense	probably damaging	0.99
R2568:2410089E03Rik	UTSW	15	8,201,269 (GRCm38)	missense	possibly damaging	0.70
R2845:2410089E03Rik	UTSW	15	8,216,380 (GRCm38)	missense	probably damaging	1.00
R2913:2410089E03Rik	UTSW	15	8,270,685 (GRCm38)	missense	unknown
R3056:2410089E03Rik	UTSW	15	8,251,007 (GRCm38)	missense	unknown
R3706:2410089E03Rik	UTSW	15	8,259,816 (GRCm38)	missense	unknown
R3707:2410089E03Rik	UTSW	15	8,259,816 (GRCm38)	missense	unknown
R3870:2410089E03Rik	UTSW	15	8,218,464 (GRCm38)	missense	probably damaging	0.98
R3877:2410089E03Rik	UTSW	15	8,221,943 (GRCm38)	missense	probably benign
R3886:2410089E03Rik	UTSW	15	8,171,805 (GRCm38)	missense	probably damaging	0.98
R4057:2410089E03Rik	UTSW	15	8,219,025 (GRCm38)	missense	probably benign	0.08
R4090:2410089E03Rik	UTSW	15	8,212,358 (GRCm38)	splice site	probably null
R4362:2410089E03Rik	UTSW	15	8,270,745 (GRCm38)	missense	unknown
R4363:2410089E03Rik	UTSW	15	8,270,745 (GRCm38)	missense	unknown
R4445:2410089E03Rik	UTSW	15	8,252,188 (GRCm38)	missense	unknown
R4581:2410089E03Rik	UTSW	15	8,171,798 (GRCm38)	missense	possibly damaging	0.85
R4587:2410089E03Rik	UTSW	15	8,201,152 (GRCm38)	missense	possibly damaging	0.50
R4659:2410089E03Rik	UTSW	15	8,216,276 (GRCm38)	intron	probably benign
R4663:2410089E03Rik	UTSW	15	8,218,455 (GRCm38)	missense	probably benign	0.31
R4779:2410089E03Rik	UTSW	15	8,218,838 (GRCm38)	missense	probably benign	0.04
R4812:2410089E03Rik	UTSW	15	8,201,123 (GRCm38)	splice site	probably null
R4850:2410089E03Rik	UTSW	15	8,262,938 (GRCm38)	missense	unknown
R4896:2410089E03Rik	UTSW	15	8,221,937 (GRCm38)	missense	probably benign	0.00
R5273:2410089E03Rik	UTSW	15	8,262,938 (GRCm38)	missense	unknown
R5273:2410089E03Rik	UTSW	15	8,244,341 (GRCm38)	missense	probably damaging	0.98
R5303:2410089E03Rik	UTSW	15	8,260,690 (GRCm38)	splice site	probably null
R5307:2410089E03Rik	UTSW	15	8,260,690 (GRCm38)	splice site	probably null
R5308:2410089E03Rik	UTSW	15	8,260,690 (GRCm38)	splice site	probably null
R5373:2410089E03Rik	UTSW	15	8,270,803 (GRCm38)	missense	unknown
R5374:2410089E03Rik	UTSW	15	8,270,803 (GRCm38)	missense	unknown
R5386:2410089E03Rik	UTSW	15	8,194,413 (GRCm38)	missense	probably damaging	1.00
R5534:2410089E03Rik	UTSW	15	8,228,835 (GRCm38)	missense	probably benign	0.06
R5720:2410089E03Rik	UTSW	15	8,203,687 (GRCm38)	missense	probably benign	0.35
R5891:2410089E03Rik	UTSW	15	8,188,589 (GRCm38)	missense	probably benign	0.00
R5932:2410089E03Rik	UTSW	15	8,244,595 (GRCm38)	splice site	probably null
R6053:2410089E03Rik	UTSW	15	8,188,461 (GRCm38)	missense	probably benign	0.35
R6166:2410089E03Rik	UTSW	15	8,186,560 (GRCm38)	missense	probably benign	0.00
R6245:2410089E03Rik	UTSW	15	8,178,418 (GRCm38)	missense	probably benign	0.01
R6246:2410089E03Rik	UTSW	15	8,210,014 (GRCm38)	missense	probably damaging	1.00
R6541:2410089E03Rik	UTSW	15	8,219,295 (GRCm38)	missense	possibly damaging	0.48
R6622:2410089E03Rik	UTSW	15	8,244,222 (GRCm38)	missense	probably damaging	0.98
R6707:2410089E03Rik	UTSW	15	8,223,122 (GRCm38)	missense	probably benign	0.39
R6729:2410089E03Rik	UTSW	15	8,188,601 (GRCm38)	splice site	probably null
R6805:2410089E03Rik	UTSW	15	8,244,306 (GRCm38)	missense	probably benign	0.07
R6806:2410089E03Rik	UTSW	15	8,186,858 (GRCm38)	missense	possibly damaging	0.55
R6813:2410089E03Rik	UTSW	15	8,229,282 (GRCm38)	missense	probably benign
R6830:2410089E03Rik	UTSW	15	8,176,184 (GRCm38)	missense	probably benign	0.04
R6845:2410089E03Rik	UTSW	15	8,221,904 (GRCm38)	missense	possibly damaging	0.84
R6894:2410089E03Rik	UTSW	15	8,187,368 (GRCm38)	missense	probably damaging	0.99
R6970:2410089E03Rik	UTSW	15	8,187,548 (GRCm38)	missense	probably benign	0.01
R6991:2410089E03Rik	UTSW	15	8,252,206 (GRCm38)	missense	unknown
R7003:2410089E03Rik	UTSW	15	8,228,762 (GRCm38)	missense	probably damaging	0.99
R7088:2410089E03Rik	UTSW	15	8,218,947 (GRCm38)	missense	probably benign	0.16
R7104:2410089E03Rik	UTSW	15	8,194,444 (GRCm38)	missense	possibly damaging	0.83
R7311:2410089E03Rik	UTSW	15	8,180,915 (GRCm38)	missense	probably damaging	1.00
R7374:2410089E03Rik	UTSW	15	8,247,247 (GRCm38)	missense	unknown
R7446:2410089E03Rik	UTSW	15	8,232,080 (GRCm38)	missense	probably damaging	0.98
R7539:2410089E03Rik	UTSW	15	8,201,244 (GRCm38)	missense	probably benign	0.19
R7543:2410089E03Rik	UTSW	15	8,225,392 (GRCm38)	missense	unknown
R7558:2410089E03Rik	UTSW	15	8,225,367 (GRCm38)	missense	unknown
R7629:2410089E03Rik	UTSW	15	8,227,067 (GRCm38)	nonsense	probably null
R7635:2410089E03Rik	UTSW	15	8,226,920 (GRCm38)	missense	probably benign	0.01
R7644:2410089E03Rik	UTSW	15	8,223,127 (GRCm38)	missense	probably benign	0.00
R7705:2410089E03Rik	UTSW	15	8,182,252 (GRCm38)	missense	probably damaging	1.00
R7752:2410089E03Rik	UTSW	15	8,269,706 (GRCm38)	missense	unknown
R7754:2410089E03Rik	UTSW	15	8,243,826 (GRCm38)	missense	possibly damaging	0.53
R7757:2410089E03Rik	UTSW	15	8,252,227 (GRCm38)	missense	unknown
R7836:2410089E03Rik	UTSW	15	8,203,757 (GRCm38)	missense	probably damaging	0.97
R7875:2410089E03Rik	UTSW	15	8,209,962 (GRCm38)	missense	probably benign	0.18
R7901:2410089E03Rik	UTSW	15	8,269,706 (GRCm38)	missense	unknown
R7983:2410089E03Rik	UTSW	15	8,221,815 (GRCm38)	missense	probably benign	0.01
R8030:2410089E03Rik	UTSW	15	8,230,303 (GRCm38)	missense	probably damaging	1.00
R8088:2410089E03Rik	UTSW	15	8,186,318 (GRCm38)	missense	probably benign	0.00
R8231:2410089E03Rik	UTSW	15	8,219,027 (GRCm38)	missense	probably benign	0.16
R8443:2410089E03Rik	UTSW	15	8,201,151 (GRCm38)	missense	probably benign	0.03
R8480:2410089E03Rik	UTSW	15	8,187,458 (GRCm38)	missense	possibly damaging	0.63
R8693:2410089E03Rik	UTSW	15	8,229,008 (GRCm38)	missense	probably benign	0.15
R8785:2410089E03Rik	UTSW	15	8,174,760 (GRCm38)	missense	probably benign	0.39
R8791:2410089E03Rik	UTSW	15	8,187,260 (GRCm38)	missense	probably damaging	1.00
R8822:2410089E03Rik	UTSW	15	8,171,778 (GRCm38)	missense	probably damaging	1.00
R8831:2410089E03Rik	UTSW	15	8,182,136 (GRCm38)	missense	probably benign	0.09
R8932:2410089E03Rik	UTSW	15	8,194,375 (GRCm38)	missense	probably damaging	1.00
R8968:2410089E03Rik	UTSW	15	8,201,281 (GRCm38)	missense	possibly damaging	0.84
R8973:2410089E03Rik	UTSW	15	8,203,793 (GRCm38)	missense	probably damaging	1.00
R9036:2410089E03Rik	UTSW	15	8,223,138 (GRCm38)	missense	possibly damaging	0.63
R9134:2410089E03Rik	UTSW	15	8,199,232 (GRCm38)	missense	probably damaging	0.99
R9197:2410089E03Rik	UTSW	15	8,251,052 (GRCm38)	missense	unknown
R9259:2410089E03Rik	UTSW	15	8,203,303 (GRCm38)	missense	possibly damaging	0.82
R9294:2410089E03Rik	UTSW	15	8,203,327 (GRCm38)	missense	probably benign	0.00
R9328:2410089E03Rik	UTSW	15	8,186,208 (GRCm38)	missense	probably damaging	1.00
R9563:2410089E03Rik	UTSW	15	8,187,079 (GRCm38)	missense	probably benign	0.20
R9680:2410089E03Rik	UTSW	15	8,202,301 (GRCm38)	missense	possibly damaging	0.68
R9721:2410089E03Rik	UTSW	15	8,225,409 (GRCm38)	missense	unknown
R9779:2410089E03Rik	UTSW	15	8,201,302 (GRCm38)	missense	possibly damaging	0.93
R9780:2410089E03Rik	UTSW	15	8,228,639 (GRCm38)	missense	probably benign	0.00
U24488:2410089E03Rik	UTSW	15	8,182,210 (GRCm38)	missense	probably damaging	1.00
X0023:2410089E03Rik	UTSW	15	8,247,031 (GRCm38)	missense	unknown
Z1177:2410089E03Rik	UTSW	15	8,209,989 (GRCm38)	missense	probably damaging	0.98
Z1177:2410089E03Rik	UTSW	15	8,174,972 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CTGTCCTCTCTAAACAGTGTGG -3'
(R):5'- AGCGGATCATCCACTCTACC -3'

Sequencing Primer
(F):5'- CTCTCTAAACAGTGTGGGTGCC -3'
(R):5'- ATCGCCGAACATGCTCTG -3'

Posted On

2022-03-25