Incidental Mutation 'R9270:Umodl1'
| ID |
702876 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9270 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
30954679-31010708 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 30966704 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 139
(D139G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067443
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066554
AA Change: D139G
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
AA Change: D139G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066981
AA Change: D139G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
AA Change: D139G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000114555
AA Change: D139G
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
AA Change: D139G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.2894 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
100% (85/85) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actrt3 |
T |
A |
3: 30,598,632 (GRCm38) |
E104D |
probably damaging |
Het |
| Aig1 |
T |
C |
10: 13,653,761 (GRCm38) |
|
probably null |
Het |
| Arih2 |
A |
T |
9: 108,616,691 (GRCm38) |
D174E |
probably damaging |
Het |
| Asprv1 |
T |
C |
6: 86,629,095 (GRCm38) |
F308L |
probably damaging |
Het |
| Baiap2l2 |
A |
G |
15: 79,284,005 (GRCm38) |
|
probably null |
Het |
| Btla |
T |
C |
16: 45,244,293 (GRCm38) |
F203L |
possibly damaging |
Het |
| C1rb |
A |
T |
6: 124,574,988 (GRCm38) |
D283V |
probably damaging |
Het |
| C87436 |
C |
G |
6: 86,465,831 (GRCm38) |
Q462E |
probably benign |
Het |
| Ccdc149 |
T |
C |
5: 52,406,010 (GRCm38) |
D147G |
possibly damaging |
Het |
| Chd6 |
A |
T |
2: 161,029,873 (GRCm38) |
L214* |
probably null |
Het |
| Chrna4 |
C |
A |
2: 181,028,850 (GRCm38) |
R371L |
possibly damaging |
Het |
| Cpne5 |
A |
G |
17: 29,225,189 (GRCm38) |
|
probably null |
Het |
| Cr1l |
T |
C |
1: 195,106,896 (GRCm38) |
E400G |
possibly damaging |
Het |
| Creb3l2 |
T |
C |
6: 37,355,648 (GRCm38) |
N304D |
probably damaging |
Het |
| Cyp17a1 |
T |
C |
19: 46,667,591 (GRCm38) |
T420A |
probably benign |
Het |
| Cyp24a1 |
A |
G |
2: 170,485,933 (GRCm38) |
I463T |
probably damaging |
Het |
| Cyp3a41b |
A |
T |
5: 145,578,163 (GRCm38) |
I84N |
probably damaging |
Het |
| Dnajc6 |
G |
A |
4: 101,639,362 (GRCm38) |
V909M |
possibly damaging |
Het |
| Dtl |
A |
G |
1: 191,556,811 (GRCm38) |
Y264H |
probably damaging |
Het |
| Dynlt5 |
A |
G |
4: 102,988,758 (GRCm38) |
|
probably null |
Het |
| Dysf |
C |
T |
6: 84,100,234 (GRCm38) |
R660* |
probably null |
Het |
| Egf |
A |
G |
3: 129,735,800 (GRCm38) |
|
probably null |
Het |
| Eva1c |
T |
C |
16: 90,904,343 (GRCm38) |
S402P |
probably benign |
Het |
| Fcho2 |
A |
T |
13: 98,789,361 (GRCm38) |
|
probably null |
Het |
| Fhdc1 |
G |
A |
3: 84,444,983 (GRCm38) |
R197C |
unknown |
Het |
| Foxa2 |
T |
A |
2: 148,044,506 (GRCm38) |
M136L |
probably benign |
Het |
| Gm10226 |
T |
C |
17: 21,691,959 (GRCm38) |
C34R |
possibly damaging |
Het |
| Gm8947 |
T |
C |
1: 151,193,102 (GRCm38) |
S229P |
probably benign |
Het |
| Ift56 |
C |
T |
6: 38,389,174 (GRCm38) |
|
probably benign |
Het |
| Ighv9-2 |
A |
T |
12: 114,109,276 (GRCm38) |
S26T |
probably damaging |
Het |
| Itpr3 |
G |
A |
17: 27,118,677 (GRCm38) |
|
probably benign |
Het |
| Kat6a |
T |
G |
8: 22,930,174 (GRCm38) |
I745M |
probably damaging |
Het |
| Klhdc1 |
T |
C |
12: 69,263,194 (GRCm38) |
L290P |
probably damaging |
Het |
| Lcp2 |
C |
T |
11: 34,089,688 (GRCm38) |
T496I |
|
Het |
| Map4k4 |
T |
C |
1: 40,003,763 (GRCm38) |
W593R |
probably benign |
Het |
| Mefv |
T |
G |
16: 3,717,977 (GRCm38) |
Q29P |
probably damaging |
Het |
| Mgat5b |
T |
C |
11: 116,968,443 (GRCm38) |
Y34H |
|
Het |
| Mlip |
C |
T |
9: 77,229,798 (GRCm38) |
R609Q |
probably benign |
Het |
| Muc2 |
A |
G |
7: 141,704,267 (GRCm38) |
D34G |
|
Het |
| Nbeal1 |
C |
T |
1: 60,268,389 (GRCm38) |
P1687S |
possibly damaging |
Het |
| Notch1 |
T |
A |
2: 26,479,883 (GRCm38) |
I477L |
probably damaging |
Het |
| Odad2 |
T |
A |
18: 7,217,846 (GRCm38) |
K623* |
probably null |
Het |
| Olfr364-ps1 |
G |
A |
2: 37,147,035 (GRCm38) |
M274I |
probably benign |
Het |
| Or1s2 |
T |
C |
19: 13,780,969 (GRCm38) |
V117A |
probably benign |
Het |
| Or4a2 |
A |
T |
2: 89,418,368 (GRCm38) |
L15Q |
probably damaging |
Het |
| Or51v8 |
T |
A |
7: 103,670,917 (GRCm38) |
N38I |
probably damaging |
Het |
| Or6c214 |
A |
G |
10: 129,755,279 (GRCm38) |
M57T |
probably damaging |
Het |
| Pak5 |
A |
T |
2: 136,116,768 (GRCm38) |
S133R |
probably damaging |
Het |
| Pcyt1a |
C |
A |
16: 32,466,514 (GRCm38) |
D187E |
probably benign |
Het |
| Pdlim7 |
G |
T |
13: 55,507,541 (GRCm38) |
T161K |
probably damaging |
Het |
| Phf8-ps |
A |
C |
17: 33,067,727 (GRCm38) |
C34G |
probably damaging |
Het |
| Pik3r4 |
A |
G |
9: 105,669,909 (GRCm38) |
K962R |
probably benign |
Het |
| Pkd1l2 |
T |
C |
8: 117,032,694 (GRCm38) |
K1516E |
probably damaging |
Het |
| Plk5 |
C |
G |
10: 80,357,996 (GRCm38) |
R40G |
probably damaging |
Het |
| Ptchd3 |
A |
T |
11: 121,842,354 (GRCm38) |
Y690F |
probably benign |
Het |
| Ptpn13 |
A |
T |
5: 103,501,869 (GRCm38) |
R379S |
possibly damaging |
Het |
| Rbm27 |
C |
T |
18: 42,305,764 (GRCm38) |
A410V |
probably benign |
Het |
| Rnase4 |
A |
G |
14: 51,105,205 (GRCm38) |
T129A |
probably benign |
Het |
| Serpinb11 |
C |
T |
1: 107,376,803 (GRCm38) |
T166I |
probably benign |
Het |
| Shank2 |
A |
G |
7: 144,409,968 (GRCm38) |
T438A |
possibly damaging |
Het |
| Slc13a2 |
T |
C |
11: 78,404,432 (GRCm38) |
N172D |
probably damaging |
Het |
| Slc2a8 |
A |
G |
2: 32,974,852 (GRCm38) |
F428L |
probably damaging |
Het |
| Slc38a6 |
T |
C |
12: 73,351,770 (GRCm38) |
M358T |
probably benign |
Het |
| Snx29 |
A |
G |
16: 11,395,291 (GRCm38) |
H107R |
probably benign |
Het |
| Spint3 |
G |
A |
2: 164,573,234 (GRCm38) |
A21V |
probably benign |
Het |
| Susd1 |
A |
T |
4: 59,412,226 (GRCm38) |
V162E |
probably benign |
Het |
| Syne2 |
T |
G |
12: 75,931,060 (GRCm38) |
N1426K |
probably damaging |
Het |
| Synj2 |
T |
C |
17: 6,017,600 (GRCm38) |
V638A |
possibly damaging |
Het |
| Thada |
A |
T |
17: 84,231,161 (GRCm38) |
L1473Q |
probably damaging |
Het |
| Trim36 |
G |
A |
18: 46,167,513 (GRCm38) |
S697L |
possibly damaging |
Het |
| Ttbk1 |
A |
T |
17: 46,470,591 (GRCm38) |
I412N |
possibly damaging |
Het |
| Tubb2a |
T |
C |
13: 34,074,595 (GRCm38) |
D404G |
probably damaging |
Het |
| Tyk2 |
T |
A |
9: 21,124,545 (GRCm38) |
N114Y |
probably damaging |
Het |
| Urb2 |
A |
G |
8: 124,023,453 (GRCm38) |
|
probably benign |
Het |
| Vmn2r101 |
T |
A |
17: 19,589,982 (GRCm38) |
N343K |
probably benign |
Het |
| Vnn1 |
A |
G |
10: 23,904,566 (GRCm38) |
D484G |
probably damaging |
Het |
| Vps13b |
A |
G |
15: 35,770,773 (GRCm38) |
T2121A |
probably benign |
Het |
| Wdr81 |
T |
C |
11: 75,454,390 (GRCm38) |
E17G |
probably benign |
Het |
| Wnk2 |
T |
G |
13: 49,071,029 (GRCm38) |
K1117Q |
probably benign |
Het |
| Zbtb46 |
C |
T |
2: 181,424,345 (GRCm38) |
R4Q |
probably benign |
Het |
| Zfp608 |
T |
A |
18: 54,899,118 (GRCm38) |
K583N |
probably damaging |
Het |
| Zfp729b |
A |
T |
13: 67,592,361 (GRCm38) |
L595H |
probably damaging |
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,008,750 (GRCm38) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
30,996,264 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
30,996,259 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
30,998,826 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
30,996,255 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
30,982,320 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
30,973,768 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
30,987,914 (GRCm38) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
30,986,117 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
30,994,815 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
30,968,441 (GRCm38) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
30,998,654 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
30,989,488 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
30,986,499 (GRCm38) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
30,996,355 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
30,959,155 (GRCm38) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
30,988,057 (GRCm38) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
30,986,116 (GRCm38) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
30,986,465 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
30,986,554 (GRCm38) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
30,986,554 (GRCm38) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
30,959,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
30,968,477 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
30,968,477 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
30,984,028 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0831:Umodl1
|
UTSW |
17 |
30,996,351 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1078:Umodl1
|
UTSW |
17 |
30,959,373 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,002,798 (GRCm38) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
30,959,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
30,986,504 (GRCm38) |
missense |
probably benign |
0.05 |
|
R1459:Umodl1
|
UTSW |
17 |
30,982,258 (GRCm38) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
30,959,229 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
30,987,968 (GRCm38) |
missense |
probably benign |
|
|
R1757:Umodl1
|
UTSW |
17 |
31,008,700 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1781:Umodl1
|
UTSW |
17 |
30,968,550 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1873:Umodl1
|
UTSW |
17 |
30,982,264 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
30,992,154 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
30,984,043 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
30,984,043 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,008,766 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,008,766 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
30,971,919 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
30,971,919 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
30,971,919 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
30,992,088 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
30,992,173 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
30,989,528 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,002,863 (GRCm38) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
30,984,789 (GRCm38) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
30,959,367 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
30,988,065 (GRCm38) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
30,994,815 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4684:Umodl1
|
UTSW |
17 |
30,998,114 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4769:Umodl1
|
UTSW |
17 |
30,984,002 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4887:Umodl1
|
UTSW |
17 |
31,008,665 (GRCm38) |
missense |
probably benign |
0.06 |
|
R4888:Umodl1
|
UTSW |
17 |
30,999,201 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
30,986,081 (GRCm38) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
30,986,485 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
30,984,092 (GRCm38) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
30,980,359 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
30,986,465 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
30,982,289 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
30,994,787 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
30,996,282 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,002,892 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
30,982,351 (GRCm38) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
30,986,147 (GRCm38) |
missense |
probably benign |
0.38 |
|
R6478:Umodl1
|
UTSW |
17 |
30,959,155 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6702:Umodl1
|
UTSW |
17 |
30,986,299 (GRCm38) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
30,986,554 (GRCm38) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
30,999,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
30,982,272 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
30,982,344 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R7219:Umodl1
|
UTSW |
17 |
30,982,262 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7231:Umodl1
|
UTSW |
17 |
30,986,116 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7234:Umodl1
|
UTSW |
17 |
30,986,621 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,008,665 (GRCm38) |
missense |
probably benign |
0.06 |
|
R7392:Umodl1
|
UTSW |
17 |
30,982,332 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7401:Umodl1
|
UTSW |
17 |
30,998,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
30,988,057 (GRCm38) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
30,954,805 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
30,988,057 (GRCm38) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
30,986,456 (GRCm38) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
30,959,151 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
30,973,692 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
30,986,387 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
30,973,796 (GRCm38) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
30,971,818 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
30,984,832 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
30,983,984 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
30,973,703 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
30,966,704 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
30,959,173 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9341:Umodl1
|
UTSW |
17 |
30,998,727 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
30,998,727 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
30,996,393 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9569:Umodl1
|
UTSW |
17 |
30,998,169 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9615:Umodl1
|
UTSW |
17 |
30,998,178 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
30,959,350 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTTCAATTAGGGTTGATGCCTT -3'
(R):5'- CAGGGCTCTAGGGACCAC -3'
Sequencing Primer
(F):5'- GTACTAGGAACTGAACCTTGGTCC -3'
(R):5'- CGTGGGGACAGGCAGAC -3'
|
| Posted On |
2022-03-25 |
Incidental Mutation