Incidental Mutation 'R9271:Nlrp9a'
| ID |
702923 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlrp9a
|
| Ensembl Gene |
ENSMUSG00000054102 |
| Gene Name |
NLR family, pyrin domain containing 9A |
| Synonyms |
Nalp9a, Nalp-theta, D7Ertd565e |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.070)
|
| Stock # |
R9271 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
26234448-26273573 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 26261944 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Leucine
at position 698
(M698L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000104024
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071780]
[ENSMUST00000108387]
[ENSMUST00000117252]
[ENSMUST00000122040]
[ENSMUST00000153452]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000071780
AA Change: M643L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000071685
Gene: ENSMUSG00000054102
AA Change: M643L
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108387
AA Change: M698L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000104024
Gene: ENSMUSG00000054102
AA Change: M698L
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
7.7e-33 |
PFAM |
|
LRR
|
631 |
658 |
1.42e0 |
SMART |
|
LRR
|
692 |
719 |
1.42e0 |
SMART |
|
LRR
|
748 |
775 |
2.32e-1 |
SMART |
|
LRR
|
777 |
804 |
3e0 |
SMART |
|
LRR
|
805 |
832 |
1.12e-3 |
SMART |
|
LRR
|
834 |
861 |
2.17e0 |
SMART |
|
LRR
|
862 |
889 |
2.27e-4 |
SMART |
|
LRR
|
891 |
918 |
2.02e2 |
SMART |
|
LRR
|
919 |
946 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117252
AA Change: M643L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000112398
Gene: ENSMUSG00000054102
AA Change: M643L
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
8.8e-34 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
Blast:LRR
|
666 |
692 |
1e-5 |
BLAST |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.39e0 |
SMART |
|
LRR
|
807 |
834 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122040
AA Change: M643L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000113318
Gene: ENSMUSG00000054102
AA Change: M643L
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000153452
AA Change: M609L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000120498
Gene: ENSMUSG00000054102
AA Change: M609L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NACHT
|
54 |
222 |
6.9e-33 |
PFAM |
|
LRR
|
542 |
569 |
1.42e0 |
SMART |
|
LRR
|
603 |
630 |
1.42e0 |
SMART |
|
Blast:LRR
|
632 |
657 |
1e-5 |
BLAST |
|
LRR
|
659 |
686 |
2.32e-1 |
SMART |
|
LRR
|
688 |
715 |
3e0 |
SMART |
|
LRR
|
716 |
743 |
1.12e-3 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
100% (107/107) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 111 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aatk |
A |
T |
11: 119,901,940 (GRCm39) |
S819T |
probably damaging |
Het |
| Abca13 |
A |
T |
11: 9,241,698 (GRCm39) |
D1187V |
probably damaging |
Het |
| Ak9 |
C |
A |
10: 41,300,623 (GRCm39) |
T1611K |
unknown |
Het |
| Als2 |
G |
T |
1: 59,242,189 (GRCm39) |
T622K |
probably benign |
Het |
| Ankrd40 |
G |
A |
11: 94,225,262 (GRCm39) |
A98T |
probably benign |
Het |
| Ap1b1 |
T |
C |
11: 4,973,174 (GRCm39) |
L339P |
probably damaging |
Het |
| Appl1 |
A |
C |
14: 26,669,084 (GRCm39) |
H363Q |
probably benign |
Het |
| Atf6 |
T |
C |
1: 170,622,245 (GRCm39) |
N459D |
probably damaging |
Het |
| Ccdc6 |
A |
T |
10: 70,024,993 (GRCm39) |
Q432L |
unknown |
Het |
| Ccl21a |
T |
A |
4: 42,773,486 (GRCm39) |
Q84L |
probably damaging |
Het |
| Cct4 |
A |
G |
11: 22,951,389 (GRCm39) |
I348V |
probably benign |
Het |
| Cd300ld2 |
A |
G |
11: 114,904,550 (GRCm39) |
Y106H |
probably damaging |
Het |
| Cdh19 |
C |
T |
1: 110,876,947 (GRCm39) |
E131K |
probably damaging |
Het |
| Cdon |
A |
G |
9: 35,403,175 (GRCm39) |
D1095G |
probably damaging |
Het |
| Cep85l |
T |
A |
10: 53,157,670 (GRCm39) |
R678* |
probably null |
Het |
| Chst3 |
T |
A |
10: 60,021,465 (GRCm39) |
S461C |
probably damaging |
Het |
| Clk1 |
A |
G |
1: 58,459,312 (GRCm39) |
I149T |
possibly damaging |
Het |
| Clvs2 |
T |
A |
10: 33,389,301 (GRCm39) |
D313V |
possibly damaging |
Het |
| Dap3 |
T |
C |
3: 88,840,913 (GRCm39) |
T75A |
probably benign |
Het |
| Dnaaf1 |
T |
A |
8: 120,324,392 (GRCm39) |
F631L |
probably benign |
Het |
| Dnah14 |
A |
T |
1: 181,597,325 (GRCm39) |
N3549I |
probably benign |
Het |
| Dnah17 |
A |
T |
11: 117,931,870 (GRCm39) |
Y3701N |
probably damaging |
Het |
| Dock6 |
A |
G |
9: 21,752,796 (GRCm39) |
V339A |
possibly damaging |
Het |
| Dpp6 |
T |
A |
5: 27,803,832 (GRCm39) |
C259* |
probably null |
Het |
| Dqx1 |
A |
G |
6: 83,036,024 (GRCm39) |
T119A |
probably benign |
Het |
| Dync1h1 |
G |
T |
12: 110,583,310 (GRCm39) |
R469L |
probably benign |
Het |
| Eno4 |
C |
T |
19: 58,951,260 (GRCm39) |
A424V |
probably benign |
Het |
| Entrep1 |
A |
T |
19: 23,972,221 (GRCm39) |
I161N |
possibly damaging |
Het |
| Fads1 |
T |
A |
19: 10,163,162 (GRCm39) |
D146E |
probably damaging |
Het |
| Fam171a1 |
C |
T |
2: 3,224,543 (GRCm39) |
T303M |
probably damaging |
Het |
| Fbxw20 |
C |
T |
9: 109,050,423 (GRCm39) |
D401N |
probably benign |
Het |
| Fcho1 |
T |
A |
8: 72,163,068 (GRCm39) |
T654S |
possibly damaging |
Het |
| Flad1 |
C |
A |
3: 89,315,858 (GRCm39) |
E235* |
probably null |
Het |
| Flrt2 |
G |
T |
12: 95,745,907 (GRCm39) |
A82S |
probably benign |
Het |
| Gabrg3 |
A |
T |
7: 56,829,386 (GRCm39) |
S124T |
probably benign |
Het |
| Galt |
C |
T |
4: 41,756,777 (GRCm39) |
T139I |
probably benign |
Het |
| Garin4 |
A |
G |
1: 190,895,153 (GRCm39) |
S497P |
probably damaging |
Het |
| Gfod1 |
T |
C |
13: 43,456,861 (GRCm39) |
E38G |
possibly damaging |
Het |
| Gm10330 |
A |
G |
12: 23,829,992 (GRCm39) |
I63T |
possibly damaging |
Het |
| Gm3033 |
A |
T |
14: 3,846,968 (GRCm38) |
N28I |
|
Het |
| Gm49359 |
A |
G |
13: 62,602,867 (GRCm39) |
V111A |
probably benign |
Het |
| Gpank1 |
C |
T |
17: 35,340,734 (GRCm39) |
|
probably benign |
Het |
| Hck |
T |
C |
2: 152,973,185 (GRCm39) |
L156P |
probably damaging |
Het |
| Hcn3 |
G |
T |
3: 89,057,267 (GRCm39) |
R444S |
probably damaging |
Het |
| Hephl1 |
T |
C |
9: 14,988,236 (GRCm39) |
N624S |
probably damaging |
Het |
| Hmcn1 |
A |
G |
1: 150,632,309 (GRCm39) |
I876T |
probably damaging |
Het |
| Itga9 |
T |
A |
9: 118,500,859 (GRCm39) |
D377E |
possibly damaging |
Het |
| Itpr3 |
G |
A |
17: 27,337,651 (GRCm39) |
|
probably benign |
Het |
| Itprid1 |
G |
T |
6: 55,944,051 (GRCm39) |
R417L |
probably benign |
Het |
| Kcnk1 |
T |
A |
8: 126,752,152 (GRCm39) |
|
probably null |
Het |
| Klk1b11 |
C |
T |
7: 43,425,954 (GRCm39) |
L32F |
probably benign |
Het |
| Lta4h |
A |
G |
10: 93,310,412 (GRCm39) |
S427G |
probably benign |
Het |
| Lxn |
T |
A |
3: 67,368,651 (GRCm39) |
I122F |
probably damaging |
Het |
| Lyz1 |
A |
G |
10: 117,124,492 (GRCm39) |
V148A |
possibly damaging |
Het |
| Mael |
G |
T |
1: 166,032,424 (GRCm39) |
Q326K |
probably benign |
Het |
| Magi3 |
T |
C |
3: 103,923,264 (GRCm39) |
D1151G |
possibly damaging |
Het |
| Map3k9 |
C |
A |
12: 81,769,261 (GRCm39) |
G929V |
probably benign |
Het |
| Mcoln1 |
A |
G |
8: 3,555,771 (GRCm39) |
Y22C |
probably damaging |
Het |
| Mier3 |
G |
T |
13: 111,827,870 (GRCm39) |
M45I |
probably benign |
Het |
| Mrpl1 |
T |
C |
5: 96,371,746 (GRCm39) |
V91A |
probably damaging |
Het |
| Msra |
T |
C |
14: 64,471,269 (GRCm39) |
|
probably null |
Het |
| Myo7a |
T |
C |
7: 97,740,281 (GRCm39) |
H571R |
probably benign |
Het |
| Myom1 |
T |
A |
17: 71,374,325 (GRCm39) |
W601R |
probably damaging |
Het |
| Myom3 |
C |
T |
4: 135,505,479 (GRCm39) |
T456I |
probably benign |
Het |
| Nags |
A |
T |
11: 102,037,584 (GRCm39) |
H225L |
probably benign |
Het |
| Ncaph |
C |
A |
2: 126,958,554 (GRCm39) |
K488N |
probably damaging |
Het |
| Nkain3 |
C |
T |
4: 20,484,897 (GRCm39) |
R60H |
probably damaging |
Het |
| Nmur2 |
A |
C |
11: 55,931,308 (GRCm39) |
I134M |
probably benign |
Het |
| Nrp2 |
A |
C |
1: 62,784,670 (GRCm39) |
E273A |
probably benign |
Het |
| Nup85 |
A |
G |
11: 115,468,787 (GRCm39) |
D210G |
possibly damaging |
Het |
| Obscn |
A |
G |
11: 59,006,643 (GRCm39) |
F1173S |
probably damaging |
Het |
| Or5ac24 |
A |
T |
16: 59,165,145 (GRCm39) |
C306* |
probably null |
Het |
| Otogl |
T |
A |
10: 107,652,974 (GRCm39) |
E1126V |
probably null |
Het |
| Pfkl |
T |
C |
10: 77,833,426 (GRCm39) |
I259V |
probably benign |
Het |
| Phkg1 |
A |
T |
5: 129,893,863 (GRCm39) |
Y291N |
probably benign |
Het |
| Piezo2 |
T |
G |
18: 63,163,450 (GRCm39) |
H2156P |
probably damaging |
Het |
| Piezo2 |
C |
A |
18: 63,208,790 (GRCm39) |
V1408L |
probably damaging |
Het |
| Pira13 |
T |
A |
7: 3,819,997 (GRCm39) |
E640V |
unknown |
Het |
| Pkd2 |
A |
G |
5: 104,626,959 (GRCm39) |
|
probably null |
Het |
| Plekhg3 |
A |
G |
12: 76,622,694 (GRCm39) |
T646A |
probably benign |
Het |
| Plk5 |
C |
G |
10: 80,193,830 (GRCm39) |
R40G |
probably damaging |
Het |
| Ppp1r12a |
T |
C |
10: 108,098,224 (GRCm39) |
S838P |
probably damaging |
Het |
| Rarb |
A |
T |
14: 16,435,235 (GRCm38) |
Y270* |
probably null |
Het |
| Rbm15 |
T |
C |
3: 107,239,312 (GRCm39) |
E362G |
possibly damaging |
Het |
| Rcan1 |
A |
G |
16: 92,262,741 (GRCm39) |
F76L |
|
Het |
| Rdh19 |
T |
C |
10: 127,696,142 (GRCm39) |
L298P |
probably damaging |
Het |
| Rims1 |
T |
A |
1: 22,498,773 (GRCm39) |
H57L |
|
Het |
| Rlf |
T |
C |
4: 121,004,751 (GRCm39) |
T1520A |
probably benign |
Het |
| Rnase1 |
T |
A |
14: 51,382,964 (GRCm39) |
H130L |
possibly damaging |
Het |
| Samd8 |
T |
A |
14: 21,842,569 (GRCm39) |
M360K |
probably damaging |
Het |
| Samhd1 |
A |
G |
2: 156,956,205 (GRCm39) |
L329P |
probably damaging |
Het |
| Scube1 |
C |
T |
15: 83,494,394 (GRCm39) |
E878K |
probably damaging |
Het |
| Sema3b |
T |
C |
9: 107,476,154 (GRCm39) |
Y689C |
probably damaging |
Het |
| Semp2l2a |
T |
C |
8: 13,886,697 (GRCm39) |
T465A |
possibly damaging |
Het |
| Sgo1 |
T |
C |
17: 53,983,931 (GRCm39) |
|
probably benign |
Het |
| Sh3pxd2b |
A |
T |
11: 32,373,361 (GRCm39) |
N843Y |
possibly damaging |
Het |
| Slco1a6 |
C |
T |
6: 142,035,575 (GRCm39) |
C583Y |
probably damaging |
Het |
| Smg1 |
A |
C |
7: 117,811,786 (GRCm39) |
V88G |
unknown |
Het |
| Spata24 |
T |
A |
18: 35,790,054 (GRCm39) |
N146Y |
probably damaging |
Het |
| Tcf3 |
C |
A |
10: 80,253,191 (GRCm39) |
V258L |
probably benign |
Het |
| Thap1 |
CAGCATCTGCTCGGAGCA |
CAGCA |
8: 26,650,884 (GRCm39) |
|
probably null |
Het |
| Tiam2 |
T |
C |
17: 3,465,011 (GRCm39) |
Y247H |
probably damaging |
Het |
| Ticrr |
T |
C |
7: 79,310,604 (GRCm39) |
F173L |
possibly damaging |
Het |
| Tpp2 |
A |
G |
1: 43,993,811 (GRCm39) |
E232G |
probably damaging |
Het |
| Trank1 |
T |
A |
9: 111,174,547 (GRCm39) |
V138E |
probably damaging |
Het |
| Ttll3 |
T |
C |
6: 113,369,596 (GRCm39) |
S47P |
probably benign |
Het |
| Utp4 |
C |
T |
8: 107,632,857 (GRCm39) |
T280M |
probably damaging |
Het |
| Vmn1r123 |
A |
T |
7: 20,896,794 (GRCm39) |
N229Y |
probably benign |
Het |
| Vmn1r85 |
A |
T |
7: 12,818,942 (GRCm39) |
Y67* |
probably null |
Het |
| Zbtb12 |
T |
A |
17: 35,114,320 (GRCm39) |
V35E |
possibly damaging |
Het |
| Zmym6 |
T |
A |
4: 127,017,854 (GRCm39) |
F1212I |
probably damaging |
Het |
|
| Other mutations in Nlrp9a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00659:Nlrp9a
|
APN |
7 |
26,257,050 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL00895:Nlrp9a
|
APN |
7 |
26,258,103 (GRCm39) |
missense |
probably benign |
|
|
IGL01081:Nlrp9a
|
APN |
7 |
26,257,519 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01148:Nlrp9a
|
APN |
7 |
26,257,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01368:Nlrp9a
|
APN |
7 |
26,257,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01914:Nlrp9a
|
APN |
7 |
26,256,689 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01952:Nlrp9a
|
APN |
7 |
26,257,444 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02245:Nlrp9a
|
APN |
7 |
26,257,318 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02449:Nlrp9a
|
APN |
7 |
26,264,396 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02702:Nlrp9a
|
APN |
7 |
26,264,381 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02944:Nlrp9a
|
APN |
7 |
26,258,076 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL03183:Nlrp9a
|
APN |
7 |
26,256,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0005:Nlrp9a
|
UTSW |
7 |
26,273,213 (GRCm39) |
splice site |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0013:Nlrp9a
|
UTSW |
7 |
26,270,650 (GRCm39) |
splice site |
probably null |
|
|
R0086:Nlrp9a
|
UTSW |
7 |
26,257,972 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0659:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1126:Nlrp9a
|
UTSW |
7 |
26,260,166 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1500:Nlrp9a
|
UTSW |
7 |
26,267,316 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1585:Nlrp9a
|
UTSW |
7 |
26,258,093 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1594:Nlrp9a
|
UTSW |
7 |
26,269,932 (GRCm39) |
nonsense |
probably null |
|
|
R1968:Nlrp9a
|
UTSW |
7 |
26,264,366 (GRCm39) |
missense |
probably benign |
0.23 |
|
R1989:Nlrp9a
|
UTSW |
7 |
26,273,338 (GRCm39) |
missense |
probably benign |
0.24 |
|
R2057:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2058:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2059:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2188:Nlrp9a
|
UTSW |
7 |
26,264,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2318:Nlrp9a
|
UTSW |
7 |
26,273,277 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3110:Nlrp9a
|
UTSW |
7 |
26,257,297 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3112:Nlrp9a
|
UTSW |
7 |
26,257,297 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3237:Nlrp9a
|
UTSW |
7 |
26,270,810 (GRCm39) |
nonsense |
probably null |
|
|
R3545:Nlrp9a
|
UTSW |
7 |
26,256,757 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3805:Nlrp9a
|
UTSW |
7 |
26,264,277 (GRCm39) |
nonsense |
probably null |
|
|
R4005:Nlrp9a
|
UTSW |
7 |
26,257,975 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4057:Nlrp9a
|
UTSW |
7 |
26,270,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4529:Nlrp9a
|
UTSW |
7 |
26,270,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4756:Nlrp9a
|
UTSW |
7 |
26,256,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4908:Nlrp9a
|
UTSW |
7 |
26,250,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4972:Nlrp9a
|
UTSW |
7 |
26,269,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4992:Nlrp9a
|
UTSW |
7 |
26,256,811 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5042:Nlrp9a
|
UTSW |
7 |
26,270,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5224:Nlrp9a
|
UTSW |
7 |
26,256,717 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5449:Nlrp9a
|
UTSW |
7 |
26,257,254 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5644:Nlrp9a
|
UTSW |
7 |
26,257,993 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5734:Nlrp9a
|
UTSW |
7 |
26,270,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5905:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5978:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6028:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6066:Nlrp9a
|
UTSW |
7 |
26,257,510 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6082:Nlrp9a
|
UTSW |
7 |
26,267,402 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6171:Nlrp9a
|
UTSW |
7 |
26,258,188 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6352:Nlrp9a
|
UTSW |
7 |
26,257,051 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6490:Nlrp9a
|
UTSW |
7 |
26,250,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6540:Nlrp9a
|
UTSW |
7 |
26,256,817 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7039:Nlrp9a
|
UTSW |
7 |
26,267,367 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7151:Nlrp9a
|
UTSW |
7 |
26,256,672 (GRCm39) |
nonsense |
probably null |
|
|
R7173:Nlrp9a
|
UTSW |
7 |
26,257,603 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7214:Nlrp9a
|
UTSW |
7 |
26,250,463 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7226:Nlrp9a
|
UTSW |
7 |
26,258,149 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7250:Nlrp9a
|
UTSW |
7 |
26,258,143 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7293:Nlrp9a
|
UTSW |
7 |
26,270,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7492:Nlrp9a
|
UTSW |
7 |
26,257,081 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7586:Nlrp9a
|
UTSW |
7 |
26,256,721 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7844:Nlrp9a
|
UTSW |
7 |
26,262,006 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8073:Nlrp9a
|
UTSW |
7 |
26,260,260 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8136:Nlrp9a
|
UTSW |
7 |
26,256,678 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8400:Nlrp9a
|
UTSW |
7 |
26,264,431 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8415:Nlrp9a
|
UTSW |
7 |
26,256,925 (GRCm39) |
missense |
probably benign |
|
|
R8774:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8774-TAIL:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8882:Nlrp9a
|
UTSW |
7 |
26,257,703 (GRCm39) |
nonsense |
probably null |
|
|
R9023:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9031:Nlrp9a
|
UTSW |
7 |
26,257,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9063:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9090:Nlrp9a
|
UTSW |
7 |
26,261,944 (GRCm39) |
missense |
probably benign |
|
|
R9196:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9206:Nlrp9a
|
UTSW |
7 |
26,257,656 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9265:Nlrp9a
|
UTSW |
7 |
26,258,038 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9384:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9402:Nlrp9a
|
UTSW |
7 |
26,270,030 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9424:Nlrp9a
|
UTSW |
7 |
26,260,178 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9620:Nlrp9a
|
UTSW |
7 |
26,250,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9660:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9696:Nlrp9a
|
UTSW |
7 |
26,275,033 (GRCm39) |
missense |
unknown |
|
|
R9728:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9744:Nlrp9a
|
UTSW |
7 |
26,267,266 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9794:Nlrp9a
|
UTSW |
7 |
26,264,302 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1176:Nlrp9a
|
UTSW |
7 |
26,257,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nlrp9a
|
UTSW |
7 |
26,256,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATGGTGTAAAACAAAGCCTGG -3'
(R):5'- GCTGAGAAATGTCCTAATGGGG -3'
Sequencing Primer
(F):5'- CTGGGAAAGGATTATGTAAGTTGCTC -3'
(R):5'- GGCACCTTTGTACAGGTAAATGC -3'
|
| Posted On |
2022-03-25 |
Incidental Mutation