Mutagenetix > Incidental Mutation

Incidental Mutation 'R0755:Bltp1'

70393

Institutional Source

Beutler Lab

Gene Symbol

Bltp1

Ensembl Gene

ENSMUSG00000037270

Gene Name

bridge-like lipid transfer protein family member 1

Synonyms

FSA, 4932438A13Rik, Tweek

MMRRC Submission

038935-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R0755 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

36917253-37107182 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 37000513 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 1231 (S1231P)

Ref Sequence

ENSEMBL: ENSMUSP00000148720 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057272] [ENSMUST00000152564] [ENSMUST00000152881] [ENSMUST00000211820]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000057272
AA Change: S1231P

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000060199
Gene: ENSMUSG00000037270
AA Change: S1231P

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000123916

Predicted Effect

probably benign
Transcript: ENSMUST00000128061

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000139219

Predicted Effect

probably damaging
Transcript: ENSMUST00000152564
AA Change: S1231P

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000117808
Gene: ENSMUSG00000037270
AA Change: S1231P

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000152881

SMART Domains

Protein: ENSMUSP00000118366
Gene: ENSMUSG00000037270

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000211820
AA Change: S1231P

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.1%
20x: 93.8%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial growth and differentiation, and in tumor development. [provided by RefSeq, Oct 2009]

Allele List at MGI

Other mutations in this stock

Total: 94 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A730061H03Rik	A	T	14: 55,797,638 (GRCm39)		probably benign	Het
Acin1	A	G	14: 54,889,292 (GRCm39)	M1T	probably null	Het
Akp3	G	A	1: 87,055,593 (GRCm39)	G547R	unknown	Het
Aldh1a1	A	G	19: 20,595,358 (GRCm39)	M96V	probably benign	Het
Ankfn1	T	A	11: 89,282,913 (GRCm39)	M245L	probably benign	Het
Arhgap19	T	C	19: 41,769,614 (GRCm39)	K54E	probably damaging	Het
Atp1a2	T	C	1: 172,116,948 (GRCm39)	Q223R	probably benign	Het
Atp8a2	C	T	14: 60,247,330 (GRCm39)	V557I	possibly damaging	Het
AU041133	A	T	10: 81,986,724 (GRCm39)	K126*	probably null	Het
Axin1	T	A	17: 26,401,480 (GRCm39)	Y351N	possibly damaging	Het
Baiap2l1	T	C	5: 144,221,367 (GRCm39)	K176E	probably damaging	Het
Baz2a	C	T	10: 127,955,560 (GRCm39)	T848I	possibly damaging	Het
Bbs2	A	C	8: 94,808,708 (GRCm39)	V333G	probably benign	Het
BC051019	G	A	7: 109,315,302 (GRCm39)	Q318*	probably null	Het
Cdc37	C	T	9: 21,051,160 (GRCm39)	D362N	probably damaging	Het
Cep170	A	T	1: 176,583,319 (GRCm39)	V1020E	probably damaging	Het
Chrm4	T	C	2: 91,758,747 (GRCm39)	V385A	probably benign	Het
Cntrl	G	A	2: 35,035,151 (GRCm39)	S373N	probably damaging	Het
Col23a1	G	A	11: 51,467,706 (GRCm39)	G19D	probably damaging	Het
Cyb5r4	G	T	9: 86,911,625 (GRCm39)	A100S	probably damaging	Het
Dctn1	C	T	6: 83,166,059 (GRCm39)	P115S	probably damaging	Het
Dhrs2	C	T	14: 55,472,247 (GRCm39)	T46M	probably damaging	Het
Disp2	T	C	2: 118,620,243 (GRCm39)	F325S	probably benign	Het
Dnah11	T	G	12: 117,918,564 (GRCm39)	T3456P	possibly damaging	Het
Dnah11	C	A	12: 118,162,360 (GRCm39)	V70F	probably benign	Het
Duoxa1	T	A	2: 122,135,161 (GRCm39)	T195S	probably benign	Het
Dync2i1	T	C	12: 116,175,412 (GRCm39)	I922V	probably benign	Het
Eif2ak1	T	A	5: 143,821,742 (GRCm39)	F353I	possibly damaging	Het
Esam	A	G	9: 37,447,998 (GRCm39)	T211A	probably damaging	Het
Faf1	A	G	4: 109,819,036 (GRCm39)	N636S	probably benign	Het
Fbxo25	A	G	8: 13,985,219 (GRCm39)	Y305C	probably benign	Het
Fchsd1	C	T	18: 38,101,803 (GRCm39)		probably null	Het
Fdxacb1	T	A	9: 50,683,025 (GRCm39)	D329E	possibly damaging	Het
Gvin2	A	T	7: 105,545,892 (GRCm39)	F2387I	possibly damaging	Het
Hbq1b	A	T	11: 32,237,104 (GRCm39)		probably null	Het
Hmcn2	T	A	2: 31,343,172 (GRCm39)	V4566E	probably damaging	Het
Igkv6-29	G	A	6: 70,116,053 (GRCm39)	T5I	probably benign	Het
Itfg1	A	T	8: 86,452,834 (GRCm39)	D511E	possibly damaging	Het
Jmjd1c	C	T	10: 66,932,378 (GRCm39)		probably benign	Het
Kat6b	T	A	14: 21,687,661 (GRCm39)	M570K	probably damaging	Het
Kdm4d	T	A	9: 14,375,591 (GRCm39)	K89M	probably damaging	Het
Krt19	A	T	11: 100,032,965 (GRCm39)	D194E	possibly damaging	Het
Lamc1	A	T	1: 153,123,196 (GRCm39)	Y665N	possibly damaging	Het
Lct	A	T	1: 128,221,872 (GRCm39)	S1556T	possibly damaging	Het
Macf1	A	G	4: 123,263,719 (GRCm39)	L4924P	probably damaging	Het
Mef2c	G	A	13: 83,804,472 (GRCm39)		probably null	Het
Mff	G	A	1: 82,728,326 (GRCm39)		probably null	Het
Mycbp2	A	T	14: 103,412,230 (GRCm39)	L2581Q	probably damaging	Het
Mylk	G	C	16: 34,699,845 (GRCm39)	E403Q	possibly damaging	Het
Nos3	T	A	5: 24,572,295 (GRCm39)	L123M	probably damaging	Het
Ntn5	C	T	7: 45,335,952 (GRCm39)	P128S	probably benign	Het
Nudt9	T	C	5: 104,212,920 (GRCm39)	V331A	probably damaging	Het
Or2y3	A	T	17: 38,393,085 (GRCm39)	Y261*	probably null	Het
Or7g34	T	C	9: 19,478,415 (GRCm39)	I88M	possibly damaging	Het
Pcdh7	A	T	5: 57,877,664 (GRCm39)	K406N	possibly damaging	Het
Pkdrej	T	A	15: 85,700,336 (GRCm39)	I1867L	probably benign	Het
Plppr4	C	T	3: 117,116,319 (GRCm39)	G455R	possibly damaging	Het
Pramel11	A	G	4: 143,624,299 (GRCm39)	V66A	probably damaging	Het
Prkag2	G	C	5: 25,152,629 (GRCm39)	S158R	probably benign	Het
Ptprq	T	G	10: 107,418,400 (GRCm39)	T1659P	probably benign	Het
Rasl12	A	G	9: 65,318,241 (GRCm39)	K202E	probably benign	Het
Rb1	A	C	14: 73,434,653 (GRCm39)	*922G	probably null	Het
Rsf1	C	T	7: 97,229,174 (GRCm39)	P22S	probably damaging	Het
Scn1a	T	G	2: 66,151,379 (GRCm39)	T797P	probably damaging	Het
Sgsm2	A	G	11: 74,756,323 (GRCm39)	V342A	probably damaging	Het
Slc22a7	T	G	17: 46,749,113 (GRCm39)	H68P	possibly damaging	Het
Slc4a2	G	A	5: 24,640,575 (GRCm39)	A652T	probably benign	Het
Slc5a1	T	A	5: 33,290,733 (GRCm39)	L106M	probably benign	Het
Slco1c1	C	T	6: 141,477,258 (GRCm39)	P19S	probably damaging	Het
Snx1	A	G	9: 66,005,738 (GRCm39)	F127S	probably damaging	Het
Snx31	A	T	15: 36,534,576 (GRCm39)	I199N	probably damaging	Het
Snx33	T	C	9: 56,832,741 (GRCm39)	I443V	possibly damaging	Het
Sptbn1	A	G	11: 30,089,016 (GRCm39)	F749L	probably damaging	Het
Stoml3	T	A	3: 53,405,559 (GRCm39)	Y53*	probably null	Het
Stxbp2	A	G	8: 3,692,019 (GRCm39)	T554A	probably benign	Het
Tal1	T	C	4: 114,925,573 (GRCm39)	I214T	probably damaging	Het
Tas2r140	T	A	6: 40,468,344 (GRCm39)	I58N	probably damaging	Het
Thap1	A	G	8: 26,648,501 (GRCm39)	Y8C	probably damaging	Het
Thsd7a	A	T	6: 12,555,368 (GRCm39)	L172Q	probably damaging	Het
Ube3c	T	A	5: 29,842,740 (GRCm39)	D735E	probably damaging	Het
Unc80	G	A	1: 66,544,082 (GRCm39)	D402N	probably damaging	Het
Upf1	G	T	8: 70,786,779 (GRCm39)	R902S	probably benign	Het
Urb1	A	G	16: 90,570,982 (GRCm39)	Y1276H	probably damaging	Het
Urb1	A	T	16: 90,576,026 (GRCm39)	F843L	probably benign	Het
Vmn1r198	C	T	13: 22,539,402 (GRCm39)	T296I	probably benign	Het
Vmn1r33	A	T	6: 66,588,892 (GRCm39)	S221T	probably damaging	Het
Vmn2r103	A	G	17: 19,993,830 (GRCm39)	D69G	probably benign	Het
Vmn2r14	T	G	5: 109,364,226 (GRCm39)	L563F	possibly damaging	Het
Vmn2r60	G	A	7: 41,844,869 (GRCm39)	G744D	probably damaging	Het
Vstm4	T	C	14: 32,614,601 (GRCm39)	V181A	probably damaging	Het
Wdr72	G	A	9: 74,052,376 (GRCm39)	V136I	probably benign	Het
Zfp236	T	A	18: 82,638,457 (GRCm39)	N1388Y	probably damaging	Het
Zfp53	T	A	17: 21,728,839 (GRCm39)	F291I	probably damaging	Het
Zfp944	A	T	17: 22,558,889 (GRCm39)	H119Q	possibly damaging	Het

Other mutations in Bltp1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00428:Bltp1	APN	3	37,065,876 (GRCm39)	missense	probably benign	0.00
IGL00434:Bltp1	APN	3	37,041,448 (GRCm39)	missense	probably damaging	0.98
IGL00640:Bltp1	APN	3	36,962,367 (GRCm39)	missense	probably damaging	1.00
IGL00693:Bltp1	APN	3	37,106,696 (GRCm39)	utr 3 prime	probably benign
IGL00721:Bltp1	APN	3	37,084,900 (GRCm39)	splice site	probably null
IGL00756:Bltp1	APN	3	36,962,367 (GRCm39)	missense	probably damaging	1.00
IGL00896:Bltp1	APN	3	37,093,611 (GRCm39)	missense	probably benign
IGL00902:Bltp1	APN	3	37,095,494 (GRCm39)	missense	probably damaging	1.00
IGL00980:Bltp1	APN	3	37,054,190 (GRCm39)	missense	probably damaging	1.00
IGL01019:Bltp1	APN	3	37,061,133 (GRCm39)	critical splice acceptor site	probably null
IGL01025:Bltp1	APN	3	37,100,429 (GRCm39)	missense	possibly damaging	0.89
IGL01306:Bltp1	APN	3	37,059,162 (GRCm39)	splice site	probably benign
IGL01370:Bltp1	APN	3	37,001,904 (GRCm39)	missense	probably benign	0.07
IGL01377:Bltp1	APN	3	37,027,601 (GRCm39)	critical splice donor site	probably null
IGL01401:Bltp1	APN	3	36,996,441 (GRCm39)	missense	probably benign
IGL01419:Bltp1	APN	3	37,102,270 (GRCm39)	missense	probably damaging	1.00
IGL01432:Bltp1	APN	3	37,057,908 (GRCm39)	missense	possibly damaging	0.87
IGL01433:Bltp1	APN	3	36,941,919 (GRCm39)	missense	probably damaging	1.00
IGL01452:Bltp1	APN	3	37,050,457 (GRCm39)	unclassified	probably benign
IGL01520:Bltp1	APN	3	37,027,409 (GRCm39)	nonsense	probably null
IGL01524:Bltp1	APN	3	36,996,531 (GRCm39)	missense	possibly damaging	0.90
IGL01628:Bltp1	APN	3	37,062,634 (GRCm39)	missense	probably damaging	1.00
IGL01638:Bltp1	APN	3	37,028,460 (GRCm39)	missense	probably damaging	1.00
IGL01650:Bltp1	APN	3	37,046,822 (GRCm39)	splice site	probably benign
IGL01717:Bltp1	APN	3	37,088,885 (GRCm39)	missense	probably benign
IGL01767:Bltp1	APN	3	37,095,512 (GRCm39)	missense	probably benign	0.29
IGL01813:Bltp1	APN	3	36,982,669 (GRCm39)	missense	possibly damaging	0.90
IGL01998:Bltp1	APN	3	37,011,165 (GRCm39)	missense	possibly damaging	0.49
IGL02172:Bltp1	APN	3	37,059,022 (GRCm39)	missense	probably damaging	0.99
IGL02197:Bltp1	APN	3	36,960,884 (GRCm39)	missense	probably damaging	1.00
IGL02248:Bltp1	APN	3	37,023,439 (GRCm39)	critical splice donor site	probably null
IGL02273:Bltp1	APN	3	36,975,586 (GRCm39)	splice site	probably benign
IGL02403:Bltp1	APN	3	37,084,813 (GRCm39)	missense	probably benign
IGL02492:Bltp1	APN	3	37,102,262 (GRCm39)	missense	probably benign	0.04
IGL02517:Bltp1	APN	3	37,013,017 (GRCm39)	missense	probably damaging	1.00
IGL02519:Bltp1	APN	3	36,949,464 (GRCm39)	missense	probably damaging	1.00
IGL02586:Bltp1	APN	3	37,098,757 (GRCm39)	nonsense	probably null
IGL02620:Bltp1	APN	3	37,090,094 (GRCm39)	missense	possibly damaging	0.95
IGL02621:Bltp1	APN	3	37,095,633 (GRCm39)	splice site	probably benign
IGL02670:Bltp1	APN	3	37,021,454 (GRCm39)	nonsense	probably null
IGL02806:Bltp1	APN	3	37,000,643 (GRCm39)	missense	possibly damaging	0.95
IGL02985:Bltp1	APN	3	37,012,906 (GRCm39)	missense	probably damaging	0.99
IGL03004:Bltp1	APN	3	37,019,826 (GRCm39)	splice site	probably benign
IGL03037:Bltp1	APN	3	37,023,356 (GRCm39)	missense	probably benign	0.23
IGL03037:Bltp1	APN	3	37,023,357 (GRCm39)	missense	probably damaging	1.00
IGL03062:Bltp1	APN	3	37,092,666 (GRCm39)	splice site	probably benign
IGL03137:Bltp1	APN	3	37,088,751 (GRCm39)	missense	probably damaging	0.98
IGL03150:Bltp1	APN	3	37,002,215 (GRCm39)	missense	probably damaging	1.00
IGL03204:Bltp1	APN	3	37,105,083 (GRCm39)	splice site	probably benign
IGL03207:Bltp1	APN	3	37,004,145 (GRCm39)	missense	possibly damaging	0.73
IGL03256:Bltp1	APN	3	36,960,832 (GRCm39)	splice site	probably benign
IGL03264:Bltp1	APN	3	37,056,784 (GRCm39)	missense	probably damaging	1.00
IGL03265:Bltp1	APN	3	37,102,140 (GRCm39)	missense	probably benign	0.00
IGL03303:Bltp1	APN	3	36,924,226 (GRCm39)	missense	possibly damaging	0.90
admonished	UTSW	3	37,002,453 (GRCm39)	missense	probably damaging	1.00
alerted	UTSW	3	37,087,414 (GRCm39)	missense	possibly damaging	0.85
informed	UTSW	3	37,019,998 (GRCm39)	missense	probably damaging	1.00
resolved	UTSW	3	36,975,370 (GRCm39)	missense	possibly damaging	0.60
tipped	UTSW	3	37,042,234 (GRCm39)	missense	possibly damaging	0.81
warned	UTSW	3	37,019,770 (GRCm39)	missense	probably damaging	1.00
FR4340:Bltp1	UTSW	3	37,104,901 (GRCm39)	critical splice acceptor site	probably benign
FR4737:Bltp1	UTSW	3	37,104,903 (GRCm39)	critical splice acceptor site	probably benign
PIT4515001:Bltp1	UTSW	3	37,028,385 (GRCm39)	missense	probably damaging	1.00
R0035:Bltp1	UTSW	3	37,041,747 (GRCm39)	nonsense	probably null
R0047:Bltp1	UTSW	3	36,962,341 (GRCm39)	missense	possibly damaging	0.83
R0047:Bltp1	UTSW	3	36,962,341 (GRCm39)	missense	possibly damaging	0.83
R0068:Bltp1	UTSW	3	37,006,370 (GRCm39)	missense	probably benign	0.28
R0068:Bltp1	UTSW	3	37,006,370 (GRCm39)	missense	probably benign	0.28
R0092:Bltp1	UTSW	3	37,082,308 (GRCm39)	missense	probably benign	0.41
R0233:Bltp1	UTSW	3	37,002,712 (GRCm39)	nonsense	probably null
R0233:Bltp1	UTSW	3	37,002,712 (GRCm39)	nonsense	probably null
R0256:Bltp1	UTSW	3	36,971,922 (GRCm39)	missense	probably benign	0.01
R0277:Bltp1	UTSW	3	36,997,331 (GRCm39)	nonsense	probably null
R0321:Bltp1	UTSW	3	36,960,937 (GRCm39)	splice site	probably null
R0323:Bltp1	UTSW	3	36,997,331 (GRCm39)	nonsense	probably null
R0335:Bltp1	UTSW	3	37,023,301 (GRCm39)	missense	probably damaging	1.00
R0375:Bltp1	UTSW	3	37,100,401 (GRCm39)	missense	probably damaging	0.99
R0437:Bltp1	UTSW	3	37,043,953 (GRCm39)	missense	possibly damaging	0.81
R0445:Bltp1	UTSW	3	37,054,214 (GRCm39)	missense	probably damaging	0.99
R0496:Bltp1	UTSW	3	37,041,784 (GRCm39)	missense	probably damaging	1.00
R0531:Bltp1	UTSW	3	37,090,974 (GRCm39)	missense	probably damaging	1.00
R0543:Bltp1	UTSW	3	37,050,607 (GRCm39)	missense	probably benign	0.22
R0545:Bltp1	UTSW	3	37,041,839 (GRCm39)	splice site	probably benign
R0674:Bltp1	UTSW	3	37,098,775 (GRCm39)	missense	possibly damaging	0.86
R0745:Bltp1	UTSW	3	36,982,612 (GRCm39)	missense	probably damaging	1.00
R0785:Bltp1	UTSW	3	37,013,483 (GRCm39)	splice site	probably benign
R1056:Bltp1	UTSW	3	37,098,829 (GRCm39)	missense	probably benign	0.44
R1056:Bltp1	UTSW	3	37,037,602 (GRCm39)	missense	possibly damaging	0.69
R1080:Bltp1	UTSW	3	37,042,404 (GRCm39)	missense	probably damaging	1.00
R1103:Bltp1	UTSW	3	37,050,672 (GRCm39)	missense	probably benign
R1119:Bltp1	UTSW	3	37,041,194 (GRCm39)	missense	probably damaging	1.00
R1170:Bltp1	UTSW	3	37,098,780 (GRCm39)	missense	probably damaging	0.98
R1183:Bltp1	UTSW	3	36,949,452 (GRCm39)	missense	possibly damaging	0.51
R1186:Bltp1	UTSW	3	37,050,461 (GRCm39)	unclassified	probably benign
R1201:Bltp1	UTSW	3	37,002,524 (GRCm39)	missense	probably benign
R1219:Bltp1	UTSW	3	37,000,619 (GRCm39)	nonsense	probably null
R1270:Bltp1	UTSW	3	37,006,333 (GRCm39)	missense	probably damaging	1.00
R1273:Bltp1	UTSW	3	37,041,359 (GRCm39)	missense	probably damaging	1.00
R1338:Bltp1	UTSW	3	37,106,684 (GRCm39)	missense	unknown
R1364:Bltp1	UTSW	3	37,041,179 (GRCm39)	missense	probably damaging	1.00
R1437:Bltp1	UTSW	3	36,996,578 (GRCm39)	missense	possibly damaging	0.65
R1447:Bltp1	UTSW	3	37,019,735 (GRCm39)	missense	probably damaging	0.98
R1467:Bltp1	UTSW	3	37,090,094 (GRCm39)	missense	probably damaging	0.99
R1467:Bltp1	UTSW	3	37,090,094 (GRCm39)	missense	probably damaging	0.99
R1470:Bltp1	UTSW	3	37,052,480 (GRCm39)	missense	probably benign	0.31
R1470:Bltp1	UTSW	3	37,052,480 (GRCm39)	missense	probably benign	0.31
R1481:Bltp1	UTSW	3	37,062,583 (GRCm39)	missense	probably damaging	0.99
R1528:Bltp1	UTSW	3	37,106,684 (GRCm39)	missense	unknown
R1533:Bltp1	UTSW	3	37,095,524 (GRCm39)	missense	probably damaging	1.00
R1546:Bltp1	UTSW	3	36,924,205 (GRCm39)	missense	possibly damaging	0.64
R1606:Bltp1	UTSW	3	36,996,548 (GRCm39)	missense	probably damaging	1.00
R1638:Bltp1	UTSW	3	37,089,961 (GRCm39)	nonsense	probably null
R1772:Bltp1	UTSW	3	37,013,581 (GRCm39)	missense	probably damaging	1.00
R1896:Bltp1	UTSW	3	36,962,380 (GRCm39)	nonsense	probably null
R1919:Bltp1	UTSW	3	37,061,132 (GRCm39)	critical splice acceptor site	probably null
R1983:Bltp1	UTSW	3	36,942,014 (GRCm39)	missense	probably null	1.00
R1987:Bltp1	UTSW	3	37,008,134 (GRCm39)	critical splice donor site	probably null
R1992:Bltp1	UTSW	3	37,054,181 (GRCm39)	missense	probably benign	0.32
R1999:Bltp1	UTSW	3	36,962,360 (GRCm39)	missense	probably damaging	1.00
R2004:Bltp1	UTSW	3	36,949,527 (GRCm39)	missense	possibly damaging	0.77
R2010:Bltp1	UTSW	3	36,982,700 (GRCm39)	missense	probably benign	0.09
R2027:Bltp1	UTSW	3	37,102,110 (GRCm39)	splice site	probably benign
R2039:Bltp1	UTSW	3	37,058,027 (GRCm39)	missense	possibly damaging	0.66
R2054:Bltp1	UTSW	3	37,002,002 (GRCm39)	missense	probably benign	0.01
R2089:Bltp1	UTSW	3	37,042,405 (GRCm39)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	37,042,405 (GRCm39)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	37,042,405 (GRCm39)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	37,008,119 (GRCm39)	missense	probably damaging	1.00
R2220:Bltp1	UTSW	3	36,929,679 (GRCm39)	critical splice donor site	probably null
R2374:Bltp1	UTSW	3	36,939,545 (GRCm39)	missense	probably benign	0.00
R2437:Bltp1	UTSW	3	37,012,834 (GRCm39)	splice site	probably null
R2860:Bltp1	UTSW	3	37,019,998 (GRCm39)	missense	probably damaging	1.00
R2861:Bltp1	UTSW	3	37,019,998 (GRCm39)	missense	probably damaging	1.00
R2909:Bltp1	UTSW	3	37,002,102 (GRCm39)	missense	probably damaging	1.00
R2925:Bltp1	UTSW	3	37,061,271 (GRCm39)	missense	probably damaging	0.99
R2940:Bltp1	UTSW	3	37,012,954 (GRCm39)	missense	probably damaging	1.00
R3015:Bltp1	UTSW	3	36,929,611 (GRCm39)	missense	probably damaging	1.00
R3086:Bltp1	UTSW	3	37,065,852 (GRCm39)	missense	possibly damaging	0.56
R3159:Bltp1	UTSW	3	37,013,564 (GRCm39)	missense	probably benign	0.17
R3440:Bltp1	UTSW	3	37,096,061 (GRCm39)	nonsense	probably null
R3703:Bltp1	UTSW	3	37,041,730 (GRCm39)	missense	probably damaging	1.00
R3705:Bltp1	UTSW	3	37,041,730 (GRCm39)	missense	probably damaging	1.00
R3795:Bltp1	UTSW	3	37,084,714 (GRCm39)	missense	probably benign	0.30
R3820:Bltp1	UTSW	3	37,094,583 (GRCm39)	missense	probably damaging	1.00
R3862:Bltp1	UTSW	3	36,939,547 (GRCm39)	missense	possibly damaging	0.73
R3944:Bltp1	UTSW	3	37,084,210 (GRCm39)	missense	possibly damaging	0.90
R4020:Bltp1	UTSW	3	37,066,724 (GRCm39)	intron	probably benign
R4091:Bltp1	UTSW	3	37,084,738 (GRCm39)	missense	probably benign	0.00
R4159:Bltp1	UTSW	3	36,985,232 (GRCm39)	missense	probably benign	0.00
R4231:Bltp1	UTSW	3	36,974,385 (GRCm39)	missense	probably benign	0.10
R4368:Bltp1	UTSW	3	37,042,296 (GRCm39)	nonsense	probably null
R4413:Bltp1	UTSW	3	37,012,830 (GRCm39)	splice site	probably null
R4475:Bltp1	UTSW	3	37,094,544 (GRCm39)	missense	probably damaging	1.00
R4488:Bltp1	UTSW	3	37,058,082 (GRCm39)	missense	probably null	0.93
R4489:Bltp1	UTSW	3	37,058,082 (GRCm39)	missense	probably null	0.93
R4516:Bltp1	UTSW	3	36,949,460 (GRCm39)	missense	possibly damaging	0.90
R4580:Bltp1	UTSW	3	37,084,174 (GRCm39)	missense	probably benign	0.02
R4672:Bltp1	UTSW	3	36,944,139 (GRCm39)	makesense	probably null
R4705:Bltp1	UTSW	3	37,096,038 (GRCm39)	missense	probably benign	0.03
R4735:Bltp1	UTSW	3	37,059,116 (GRCm39)	missense	possibly damaging	0.84
R4741:Bltp1	UTSW	3	36,996,524 (GRCm39)	missense	probably damaging	0.99
R4754:Bltp1	UTSW	3	37,076,615 (GRCm39)	nonsense	probably null
R4778:Bltp1	UTSW	3	36,991,214 (GRCm39)	missense	possibly damaging	0.90
R4833:Bltp1	UTSW	3	37,019,117 (GRCm39)	missense	probably damaging	0.96
R4896:Bltp1	UTSW	3	37,020,086 (GRCm39)	missense	probably damaging	1.00
R4910:Bltp1	UTSW	3	37,052,348 (GRCm39)	missense	probably damaging	1.00
R4922:Bltp1	UTSW	3	37,041,314 (GRCm39)	missense	probably damaging	1.00
R4941:Bltp1	UTSW	3	36,974,050 (GRCm39)	missense	probably benign	0.41
R4941:Bltp1	UTSW	3	36,971,851 (GRCm39)	missense	probably damaging	1.00
R4980:Bltp1	UTSW	3	36,997,461 (GRCm39)	missense	probably damaging	1.00
R5030:Bltp1	UTSW	3	36,997,548 (GRCm39)	intron	probably benign
R5049:Bltp1	UTSW	3	37,095,539 (GRCm39)	missense	probably damaging	1.00
R5049:Bltp1	UTSW	3	37,094,655 (GRCm39)	intron	probably benign
R5089:Bltp1	UTSW	3	37,041,651 (GRCm39)	missense	probably benign	0.02
R5092:Bltp1	UTSW	3	37,054,234 (GRCm39)	missense	probably benign	0.14
R5122:Bltp1	UTSW	3	37,088,906 (GRCm39)	splice site	probably null
R5210:Bltp1	UTSW	3	37,087,414 (GRCm39)	missense	possibly damaging	0.85
R5246:Bltp1	UTSW	3	37,102,199 (GRCm39)	missense	probably damaging	1.00
R5289:Bltp1	UTSW	3	37,054,258 (GRCm39)	missense	probably damaging	0.97
R5348:Bltp1	UTSW	3	37,102,295 (GRCm39)	missense	probably damaging	1.00
R5394:Bltp1	UTSW	3	36,971,817 (GRCm39)	missense	probably damaging	1.00
R5434:Bltp1	UTSW	3	36,929,665 (GRCm39)	missense	probably damaging	1.00
R5667:Bltp1	UTSW	3	36,971,826 (GRCm39)	missense	probably benign	0.00
R5686:Bltp1	UTSW	3	36,971,809 (GRCm39)	missense	probably benign	0.00
R5701:Bltp1	UTSW	3	36,975,509 (GRCm39)	missense	probably benign	0.10
R5778:Bltp1	UTSW	3	37,012,863 (GRCm39)	missense	probably damaging	1.00
R5787:Bltp1	UTSW	3	37,046,882 (GRCm39)	splice site	probably null
R5800:Bltp1	UTSW	3	37,106,592 (GRCm39)	missense	probably damaging	1.00
R5819:Bltp1	UTSW	3	37,102,749 (GRCm39)	missense	probably benign	0.12
R5820:Bltp1	UTSW	3	37,093,675 (GRCm39)	missense	probably benign	0.00
R5952:Bltp1	UTSW	3	37,019,770 (GRCm39)	missense	probably damaging	1.00
R5975:Bltp1	UTSW	3	37,023,370 (GRCm39)	missense	possibly damaging	0.64
R5996:Bltp1	UTSW	3	36,985,265 (GRCm39)	missense	probably benign	0.07
R6192:Bltp1	UTSW	3	37,042,318 (GRCm39)	missense	probably benign	0.00
R6225:Bltp1	UTSW	3	37,002,453 (GRCm39)	missense	probably damaging	1.00
R6234:Bltp1	UTSW	3	37,037,620 (GRCm39)	missense	probably benign	0.00
R6244:Bltp1	UTSW	3	37,011,148 (GRCm39)	missense	probably benign
R6263:Bltp1	UTSW	3	36,985,260 (GRCm39)	missense	probably benign	0.06
R6351:Bltp1	UTSW	3	36,962,377 (GRCm39)	missense	probably damaging	1.00
R6380:Bltp1	UTSW	3	37,087,456 (GRCm39)	missense	probably benign	0.19
R6468:Bltp1	UTSW	3	37,062,592 (GRCm39)	missense	probably damaging	1.00
R6759:Bltp1	UTSW	3	37,042,234 (GRCm39)	missense	possibly damaging	0.81
R6792:Bltp1	UTSW	3	37,065,715 (GRCm39)	critical splice acceptor site	probably null
R6809:Bltp1	UTSW	3	36,928,431 (GRCm39)	missense	probably damaging	0.98
R6841:Bltp1	UTSW	3	37,075,630 (GRCm39)	missense	probably damaging	1.00
R6959:Bltp1	UTSW	3	37,021,338 (GRCm39)	missense	probably damaging	1.00
R7102:Bltp1	UTSW	3	36,994,947 (GRCm39)	missense	probably damaging	0.99
R7188:Bltp1	UTSW	3	37,004,162 (GRCm39)	missense	probably benign	0.06
R7212:Bltp1	UTSW	3	37,102,158 (GRCm39)	missense
R7425:Bltp1	UTSW	3	37,037,543 (GRCm39)	missense	probably benign	0.02
R7425:Bltp1	UTSW	3	37,002,490 (GRCm39)	missense	probably benign
R7451:Bltp1	UTSW	3	37,076,956 (GRCm39)	splice site	probably null
R7604:Bltp1	UTSW	3	37,003,992 (GRCm39)	splice site	probably null
R7622:Bltp1	UTSW	3	37,002,562 (GRCm39)	nonsense	probably null
R7671:Bltp1	UTSW	3	36,997,380 (GRCm39)	missense	probably damaging	0.99
R7699:Bltp1	UTSW	3	37,080,303 (GRCm39)	missense	probably benign	0.00
R7699:Bltp1	UTSW	3	37,028,321 (GRCm39)	missense	possibly damaging	0.67
R7700:Bltp1	UTSW	3	37,028,321 (GRCm39)	missense	possibly damaging	0.67
R7700:Bltp1	UTSW	3	37,080,303 (GRCm39)	missense	probably benign	0.00
R7748:Bltp1	UTSW	3	37,013,484 (GRCm39)	critical splice acceptor site	probably null
R7767:Bltp1	UTSW	3	36,974,436 (GRCm39)	critical splice donor site	probably null
R7787:Bltp1	UTSW	3	36,939,557 (GRCm39)	missense	probably damaging	1.00
R7830:Bltp1	UTSW	3	37,019,081 (GRCm39)	frame shift	probably null
R7849:Bltp1	UTSW	3	37,080,477 (GRCm39)	missense
R7912:Bltp1	UTSW	3	37,061,218 (GRCm39)	missense	probably damaging	0.99
R7914:Bltp1	UTSW	3	37,000,432 (GRCm39)	missense	probably benign	0.13
R7945:Bltp1	UTSW	3	37,020,042 (GRCm39)	missense	probably benign	0.03
R8039:Bltp1	UTSW	3	36,997,363 (GRCm39)	missense	probably benign	0.12
R8101:Bltp1	UTSW	3	37,062,651 (GRCm39)	missense	probably damaging	1.00
R8143:Bltp1	UTSW	3	37,000,657 (GRCm39)	critical splice donor site	probably null
R8145:Bltp1	UTSW	3	37,052,416 (GRCm39)	missense	probably damaging	1.00
R8171:Bltp1	UTSW	3	37,029,862 (GRCm39)	missense	probably benign	0.00
R8210:Bltp1	UTSW	3	37,067,030 (GRCm39)	missense
R8250:Bltp1	UTSW	3	36,971,811 (GRCm39)	missense	probably damaging	0.99
R8369:Bltp1	UTSW	3	37,065,752 (GRCm39)	missense
R8478:Bltp1	UTSW	3	37,087,426 (GRCm39)	missense	possibly damaging	0.74
R8558:Bltp1	UTSW	3	37,102,750 (GRCm39)	missense
R8688:Bltp1	UTSW	3	37,090,066 (GRCm39)	missense
R8724:Bltp1	UTSW	3	36,945,042 (GRCm39)	missense	probably damaging	0.99
R8818:Bltp1	UTSW	3	37,050,697 (GRCm39)	missense	possibly damaging	0.60
R8869:Bltp1	UTSW	3	37,013,007 (GRCm39)	missense	probably damaging	0.99
R8887:Bltp1	UTSW	3	37,087,503 (GRCm39)	missense	possibly damaging	0.95
R8899:Bltp1	UTSW	3	37,042,429 (GRCm39)	missense	probably damaging	1.00
R8907:Bltp1	UTSW	3	37,002,295 (GRCm39)	nonsense	probably null
R8960:Bltp1	UTSW	3	37,067,132 (GRCm39)	missense	probably damaging	1.00
R8990:Bltp1	UTSW	3	36,975,370 (GRCm39)	missense	possibly damaging	0.60
R9021:Bltp1	UTSW	3	37,052,493 (GRCm39)	missense	probably benign	0.00
R9048:Bltp1	UTSW	3	37,065,926 (GRCm39)	missense
R9100:Bltp1	UTSW	3	37,098,907 (GRCm39)	missense
R9166:Bltp1	UTSW	3	37,041,516 (GRCm39)	missense	probably damaging	1.00
R9176:Bltp1	UTSW	3	37,010,852 (GRCm39)	missense	possibly damaging	0.82
R9202:Bltp1	UTSW	3	36,944,970 (GRCm39)	missense	probably benign
R9303:Bltp1	UTSW	3	37,098,969 (GRCm39)	missense
R9305:Bltp1	UTSW	3	37,098,969 (GRCm39)	missense
R9332:Bltp1	UTSW	3	37,104,989 (GRCm39)	missense
R9362:Bltp1	UTSW	3	37,011,162 (GRCm39)	missense	probably benign
R9493:Bltp1	UTSW	3	37,065,885 (GRCm39)	missense
R9534:Bltp1	UTSW	3	37,052,419 (GRCm39)	missense	probably benign	0.01
R9569:Bltp1	UTSW	3	37,066,770 (GRCm39)	missense
R9593:Bltp1	UTSW	3	37,002,090 (GRCm39)	missense	probably damaging	1.00
R9600:Bltp1	UTSW	3	37,095,565 (GRCm39)	nonsense	probably null
R9733:Bltp1	UTSW	3	37,102,732 (GRCm39)	missense
R9751:Bltp1	UTSW	3	37,065,889 (GRCm39)	missense
RF013:Bltp1	UTSW	3	37,104,906 (GRCm39)	critical splice acceptor site	probably benign
RF015:Bltp1	UTSW	3	37,104,897 (GRCm39)	critical splice acceptor site	probably benign
RF021:Bltp1	UTSW	3	37,104,897 (GRCm39)	critical splice acceptor site	probably benign
RF023:Bltp1	UTSW	3	37,104,909 (GRCm39)	critical splice acceptor site	probably benign
RF034:Bltp1	UTSW	3	37,104,909 (GRCm39)	critical splice acceptor site	probably benign
RF035:Bltp1	UTSW	3	37,104,907 (GRCm39)	critical splice acceptor site	probably benign
RF055:Bltp1	UTSW	3	37,104,906 (GRCm39)	critical splice acceptor site	probably benign
X0050:Bltp1	UTSW	3	37,011,277 (GRCm39)	missense	probably damaging	1.00
Z1088:Bltp1	UTSW	3	37,041,716 (GRCm39)	missense	probably damaging	1.00
Z1177:Bltp1	UTSW	3	37,037,589 (GRCm39)	missense	possibly damaging	0.88
Z1177:Bltp1	UTSW	3	36,974,099 (GRCm39)	missense	probably benign
Z1177:Bltp1	UTSW	3	37,090,856 (GRCm39)	missense

Predicted Primers

PCR Primer
(F):5'- GCACATTGTAGACTGTGGACCCAG -3'
(R):5'- CTGTGAAGGGTACTGTTAGGCAAGG -3'

Sequencing Primer
(F):5'- GACTGTGGACCCAGAATTTTTTATAC -3'
(R):5'- GAAGTATAACCAGTGTTTCCCCG -3'

Posted On

2013-09-30