Incidental Mutation 'R9287:Mgam'
| ID |
704000 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mgam
|
| Ensembl Gene |
ENSMUSG00000068587 |
| Gene Name |
maltase-glucoamylase |
| Synonyms |
6030407P20Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.231)
|
| Stock # |
R9287 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
40605765-40746057 bp(+) (GRCm39) |
| Type of Mutation |
intron |
| DNA Base Change (assembly) |
A to G
at 40705905 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144680
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071535]
[ENSMUST00000201148]
[ENSMUST00000202779]
[ENSMUST00000202966]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000071535
|
| SMART Domains |
Protein: ENSMUSP00000071466
Gene: ENSMUSG00000068587
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
12 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
47 |
59 |
N/A |
INTRINSIC |
|
PD
|
63 |
111 |
1.81e-8 |
SMART |
|
Pfam:NtCtMGAM_N
|
124 |
233 |
6.2e-36 |
PFAM |
|
Pfam:Glyco_hydro_31
|
323 |
795 |
3.4e-145 |
PFAM |
|
PD
|
924 |
977 |
4.52e-9 |
SMART |
|
Pfam:NtCtMGAM_N
|
988 |
1101 |
1.5e-30 |
PFAM |
|
Blast:ANK
|
1141 |
1171 |
1e-7 |
BLAST |
|
Pfam:Glyco_hydro_31
|
1189 |
1691 |
2e-139 |
PFAM |
|
low complexity region
|
1776 |
1791 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201148
|
| SMART Domains |
Protein: ENSMUSP00000143946
Gene: ENSMUSG00000068587
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
12 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
47 |
59 |
N/A |
INTRINSIC |
|
PD
|
63 |
111 |
1.81e-8 |
SMART |
|
Pfam:NtCtMGAM_N
|
124 |
233 |
6.2e-36 |
PFAM |
|
Pfam:Glyco_hydro_31
|
323 |
795 |
3.4e-145 |
PFAM |
|
PD
|
924 |
977 |
4.52e-9 |
SMART |
|
Pfam:NtCtMGAM_N
|
988 |
1101 |
1.5e-30 |
PFAM |
|
Blast:ANK
|
1141 |
1171 |
1e-7 |
BLAST |
|
Pfam:Glyco_hydro_31
|
1189 |
1691 |
2e-139 |
PFAM |
|
low complexity region
|
1776 |
1791 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000202779
|
| SMART Domains |
Protein: ENSMUSP00000144627
Gene: ENSMUSG00000068587
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Glyco_hydro_31
|
2 |
170 |
1.4e-53 |
PFAM |
|
PD
|
297 |
350 |
1.4e-14 |
SMART |
|
Pfam:NtCtMGAM_N
|
361 |
474 |
1.5e-26 |
PFAM |
|
Blast:ANK
|
514 |
544 |
7e-8 |
BLAST |
|
Pfam:Glyco_hydro_31
|
562 |
1064 |
2.2e-137 |
PFAM |
|
low complexity region
|
1149 |
1164 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000202966
|
| SMART Domains |
Protein: ENSMUSP00000144680
Gene: ENSMUSG00000068587
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
2 |
88 |
2.6e-19 |
PROSPERO |
|
PD
|
178 |
231 |
1.4e-14 |
SMART |
|
Pfam:NtCtMGAM_N
|
242 |
355 |
1.1e-26 |
PFAM |
|
Blast:ANK
|
395 |
425 |
6e-8 |
BLAST |
|
Pfam:Glyco_hydro_31
|
443 |
945 |
1.3e-137 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
100% (109/109) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null allele display abnormalities in starch digestion and prandial glucose homeostasis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 108 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9430097D07Rik |
T |
A |
2: 32,465,178 (GRCm39) |
|
probably benign |
Het |
| Aadacl2 |
C |
A |
3: 59,932,573 (GRCm39) |
H363N |
probably damaging |
Het |
| Ace3 |
T |
G |
11: 105,888,246 (GRCm39) |
S319A |
probably damaging |
Het |
| Amer3 |
C |
T |
1: 34,627,900 (GRCm39) |
P713L |
possibly damaging |
Het |
| Aoah |
T |
C |
13: 21,186,879 (GRCm39) |
L453P |
probably damaging |
Het |
| Asz1 |
A |
T |
6: 18,051,290 (GRCm39) |
L463Q |
possibly damaging |
Het |
| Bpifb6 |
T |
A |
2: 153,746,535 (GRCm39) |
V143D |
probably damaging |
Het |
| Cad |
T |
A |
5: 31,230,000 (GRCm39) |
M1499K |
possibly damaging |
Het |
| Casp9 |
T |
A |
4: 141,534,471 (GRCm39) |
C294S |
probably benign |
Het |
| Ccdc7b |
T |
A |
8: 129,890,321 (GRCm39) |
S65T |
probably benign |
Het |
| Cdh23 |
G |
A |
10: 60,143,306 (GRCm39) |
A3005V |
possibly damaging |
Het |
| Cfap54 |
T |
C |
10: 92,805,565 (GRCm39) |
Y1515C |
possibly damaging |
Het |
| Chrm5 |
A |
C |
2: 112,309,610 (GRCm39) |
F502C |
probably damaging |
Het |
| Cnst |
A |
T |
1: 179,407,108 (GRCm39) |
T52S |
possibly damaging |
Het |
| Cntn6 |
T |
C |
6: 104,809,471 (GRCm39) |
I502T |
possibly damaging |
Het |
| Col7a1 |
G |
A |
9: 108,787,457 (GRCm39) |
V617M |
unknown |
Het |
| Ctsb |
A |
G |
14: 63,370,875 (GRCm39) |
D29G |
probably benign |
Het |
| Cyp3a44 |
T |
A |
5: 145,725,202 (GRCm39) |
Q333L |
possibly damaging |
Het |
| Dnajc27 |
T |
C |
12: 4,146,256 (GRCm39) |
V95A |
possibly damaging |
Het |
| Eea1 |
T |
A |
10: 95,831,445 (GRCm39) |
Y179N |
probably damaging |
Het |
| Erbb2 |
T |
C |
11: 98,326,107 (GRCm39) |
M961T |
probably damaging |
Het |
| Fat4 |
G |
A |
3: 38,945,781 (GRCm39) |
G1558D |
probably damaging |
Het |
| Foxh1 |
T |
C |
15: 76,553,126 (GRCm39) |
E196G |
probably damaging |
Het |
| Gcc2 |
T |
A |
10: 58,105,217 (GRCm39) |
L151* |
probably null |
Het |
| Gcdh |
C |
T |
8: 85,616,313 (GRCm39) |
G294D |
probably damaging |
Het |
| Gcnt3 |
A |
T |
9: 69,941,693 (GRCm39) |
F292I |
probably damaging |
Het |
| Glod4 |
T |
C |
11: 76,128,510 (GRCm39) |
S131G |
probably benign |
Het |
| Gpc2 |
G |
A |
5: 138,272,586 (GRCm39) |
L576F |
unknown |
Het |
| Gphn |
G |
A |
12: 78,609,646 (GRCm39) |
S330N |
possibly damaging |
Het |
| Heatr5a |
C |
T |
12: 51,967,260 (GRCm39) |
C872Y |
probably damaging |
Het |
| Hephl1 |
G |
A |
9: 14,995,775 (GRCm39) |
S449L |
probably benign |
Het |
| Hrh2 |
G |
T |
13: 54,368,358 (GRCm39) |
M111I |
probably benign |
Het |
| Igfn1 |
A |
G |
1: 135,925,544 (GRCm39) |
V70A |
probably benign |
Het |
| Il2 |
G |
A |
3: 37,179,988 (GRCm39) |
T23I |
probably damaging |
Het |
| Irak4 |
A |
G |
15: 94,460,917 (GRCm39) |
T382A |
possibly damaging |
Het |
| Itih2 |
A |
G |
2: 10,128,297 (GRCm39) |
S135P |
possibly damaging |
Het |
| Kansl3 |
C |
T |
1: 36,388,497 (GRCm39) |
D457N |
probably damaging |
Het |
| Kcns3 |
A |
G |
12: 11,141,601 (GRCm39) |
I366T |
probably damaging |
Het |
| Kif26a |
C |
A |
12: 112,145,719 (GRCm39) |
Y1743* |
probably null |
Het |
| Lama4 |
A |
T |
10: 38,981,960 (GRCm39) |
I1730F |
probably damaging |
Het |
| Lax1 |
T |
C |
1: 133,607,931 (GRCm39) |
N270S |
probably benign |
Het |
| Lrp1 |
G |
T |
10: 127,403,233 (GRCm39) |
D2113E |
probably damaging |
Het |
| Lrp6 |
A |
G |
6: 134,483,259 (GRCm39) |
V482A |
probably benign |
Het |
| Luzp2 |
A |
G |
7: 54,914,108 (GRCm39) |
|
probably benign |
Het |
| Mc5r |
C |
A |
18: 68,472,200 (GRCm39) |
D186E |
probably damaging |
Het |
| Mcph1 |
A |
T |
8: 18,657,293 (GRCm39) |
|
probably null |
Het |
| Mmrn1 |
A |
C |
6: 60,952,939 (GRCm39) |
T407P |
probably damaging |
Het |
| Mrpl1 |
T |
C |
5: 96,386,806 (GRCm39) |
V265A |
probably benign |
Het |
| Mrpl15 |
C |
T |
1: 4,846,856 (GRCm39) |
G240D |
probably damaging |
Het |
| Msx1 |
A |
T |
5: 37,978,795 (GRCm39) |
M240K |
probably damaging |
Het |
| Mtf1 |
T |
C |
4: 124,724,934 (GRCm39) |
L337P |
probably damaging |
Het |
| Muc5ac |
T |
A |
7: 141,361,626 (GRCm39) |
C1646S |
probably damaging |
Het |
| Mvb12a |
C |
A |
8: 71,999,638 (GRCm39) |
T219N |
probably damaging |
Het |
| Myo16 |
G |
A |
8: 10,526,114 (GRCm39) |
V885M |
unknown |
Het |
| N4bp2 |
T |
A |
5: 65,960,855 (GRCm39) |
S509T |
probably benign |
Het |
| Nckap1 |
A |
G |
2: 80,383,750 (GRCm39) |
V144A |
possibly damaging |
Het |
| Nkx2-6 |
G |
T |
14: 69,412,404 (GRCm39) |
G191C |
possibly damaging |
Het |
| Nmnat2 |
T |
C |
1: 152,962,138 (GRCm39) |
I126T |
probably damaging |
Het |
| Nrp2 |
C |
T |
1: 62,835,014 (GRCm39) |
R863W |
probably damaging |
Het |
| Nup188 |
C |
T |
2: 30,226,726 (GRCm39) |
R1168C |
probably damaging |
Het |
| Oas3 |
T |
A |
5: 120,892,754 (GRCm39) |
D1091V |
probably damaging |
Het |
| Optn |
T |
A |
2: 5,036,126 (GRCm39) |
Q452L |
probably damaging |
Het |
| Or8b47 |
C |
T |
9: 38,435,082 (GRCm39) |
T18I |
probably damaging |
Het |
| Pcca |
G |
A |
14: 122,854,178 (GRCm39) |
V157I |
probably benign |
Het |
| Pcdha9 |
A |
G |
18: 37,132,281 (GRCm39) |
D450G |
probably benign |
Het |
| Pcnx1 |
T |
A |
12: 82,042,323 (GRCm39) |
S38T |
probably benign |
Het |
| Phrf1 |
C |
G |
7: 140,840,055 (GRCm39) |
D1083E |
probably benign |
Het |
| Plaat5 |
T |
A |
19: 7,596,691 (GRCm39) |
Y159* |
probably null |
Het |
| Plcb4 |
G |
A |
2: 135,829,817 (GRCm39) |
A947T |
probably benign |
Het |
| Ppp1r3g |
G |
A |
13: 36,152,834 (GRCm39) |
D85N |
possibly damaging |
Het |
| Pramel34 |
G |
A |
5: 93,785,969 (GRCm39) |
H104Y |
possibly damaging |
Het |
| Prom2 |
A |
C |
2: 127,380,185 (GRCm39) |
V349G |
probably damaging |
Het |
| Prrc2c |
C |
T |
1: 162,541,843 (GRCm39) |
S382N |
probably benign |
Het |
| Rai14 |
A |
T |
15: 10,592,204 (GRCm39) |
N230K |
probably benign |
Het |
| Rexo5 |
A |
T |
7: 119,402,025 (GRCm39) |
K142I |
probably damaging |
Het |
| Rgs22 |
T |
C |
15: 36,098,409 (GRCm39) |
H484R |
probably damaging |
Het |
| Rims2 |
C |
T |
15: 39,543,086 (GRCm39) |
A1440V |
probably damaging |
Het |
| Serpinb1a |
T |
C |
13: 33,026,946 (GRCm39) |
E332G |
probably damaging |
Het |
| Sh2b1 |
TGGGGACCAGCTCAGCCACGGGGACCAGCTC |
TGGGGACCAGCTCAGCCACGGGGACCAGCTCAGCCACGGGGACCAGCTC |
7: 126,066,742 (GRCm39) |
|
probably benign |
Het |
| Slc26a7 |
C |
T |
4: 14,516,165 (GRCm39) |
G555S |
possibly damaging |
Het |
| Slc4a2 |
A |
T |
5: 24,639,123 (GRCm39) |
D386V |
probably damaging |
Het |
| Slc6a17 |
C |
T |
3: 107,384,551 (GRCm39) |
V350M |
probably damaging |
Het |
| Smc2 |
A |
G |
4: 52,449,361 (GRCm39) |
Y174C |
probably damaging |
Het |
| Smoc2 |
A |
G |
17: 14,619,686 (GRCm39) |
Y355C |
probably damaging |
Het |
| Smpd1 |
T |
A |
7: 105,204,442 (GRCm39) |
V107E |
probably benign |
Het |
| Snapc1 |
T |
C |
12: 74,018,773 (GRCm39) |
|
probably benign |
Het |
| Spata31e2 |
T |
C |
1: 26,722,426 (GRCm39) |
D918G |
possibly damaging |
Het |
| Steap4 |
T |
G |
5: 8,026,683 (GRCm39) |
F215L |
probably benign |
Het |
| Tbc1d1 |
T |
A |
5: 64,435,364 (GRCm39) |
S501T |
probably damaging |
Het |
| Tec |
A |
G |
5: 72,926,117 (GRCm39) |
Y312H |
probably damaging |
Het |
| Ticrr |
C |
A |
7: 79,343,516 (GRCm39) |
T1127K |
possibly damaging |
Het |
| Tlk2 |
A |
G |
11: 105,147,722 (GRCm39) |
D438G |
probably benign |
Het |
| Tln2 |
C |
A |
9: 67,277,980 (GRCm39) |
V343L |
probably benign |
Het |
| Tmem156 |
T |
A |
5: 65,231,148 (GRCm39) |
I241F |
probably damaging |
Het |
| Tmtc1 |
G |
T |
6: 148,186,390 (GRCm39) |
N559K |
probably benign |
Het |
| Trbv4 |
A |
T |
6: 41,036,696 (GRCm39) |
I74F |
probably benign |
Het |
| Trmt1l |
C |
T |
1: 151,328,899 (GRCm39) |
P524S |
probably damaging |
Het |
| Trpa1 |
A |
T |
1: 14,956,040 (GRCm39) |
C776* |
probably null |
Het |
| Ttc41 |
T |
A |
10: 86,599,830 (GRCm39) |
S1043R |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,576,646 (GRCm39) |
L24749S |
probably damaging |
Het |
| Ube2o |
C |
T |
11: 116,471,942 (GRCm39) |
G100R |
probably damaging |
Het |
| Unc5b |
T |
C |
10: 60,609,532 (GRCm39) |
E588G |
possibly damaging |
Het |
| Usp43 |
G |
T |
11: 67,770,922 (GRCm39) |
Q571K |
probably damaging |
Het |
| Vmn1r127 |
G |
A |
7: 21,052,927 (GRCm39) |
P287L |
possibly damaging |
Het |
| Wasf3 |
T |
A |
5: 146,397,857 (GRCm39) |
M208K |
possibly damaging |
Het |
| Xab2 |
A |
G |
8: 3,663,000 (GRCm39) |
F527S |
possibly damaging |
Het |
| Zfp644 |
T |
G |
5: 106,785,774 (GRCm39) |
N258H |
possibly damaging |
Het |
| Zfp947 |
A |
C |
17: 22,364,594 (GRCm39) |
F360C |
probably damaging |
Het |
|
| Other mutations in Mgam |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01024:Mgam
|
APN |
6 |
40,619,944 (GRCm39) |
missense |
probably benign |
|
|
IGL01065:Mgam
|
APN |
6 |
40,639,644 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01402:Mgam
|
APN |
6 |
40,621,879 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01404:Mgam
|
APN |
6 |
40,621,879 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01413:Mgam
|
APN |
6 |
40,638,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01546:Mgam
|
APN |
6 |
40,631,627 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01596:Mgam
|
APN |
6 |
40,635,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02133:Mgam
|
APN |
6 |
40,620,010 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02734:Mgam
|
APN |
6 |
40,639,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB002:Mgam
|
UTSW |
6 |
40,735,985 (GRCm39) |
missense |
probably damaging |
0.99 |
|
BB012:Mgam
|
UTSW |
6 |
40,735,985 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0012:Mgam
|
UTSW |
6 |
40,742,190 (GRCm39) |
splice site |
probably null |
|
|
R0116:Mgam
|
UTSW |
6 |
40,635,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0310:Mgam
|
UTSW |
6 |
40,737,969 (GRCm39) |
splice site |
probably benign |
|
|
R0452:Mgam
|
UTSW |
6 |
40,736,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0497:Mgam
|
UTSW |
6 |
40,641,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0699:Mgam
|
UTSW |
6 |
40,619,953 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0738:Mgam
|
UTSW |
6 |
40,731,869 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1033:Mgam
|
UTSW |
6 |
40,657,558 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1403:Mgam
|
UTSW |
6 |
40,643,815 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1403:Mgam
|
UTSW |
6 |
40,643,815 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1430:Mgam
|
UTSW |
6 |
40,733,305 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1432:Mgam
|
UTSW |
6 |
40,733,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1443:Mgam
|
UTSW |
6 |
40,736,714 (GRCm39) |
nonsense |
probably null |
|
|
R1470:Mgam
|
UTSW |
6 |
40,736,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1470:Mgam
|
UTSW |
6 |
40,736,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1519:Mgam
|
UTSW |
6 |
40,638,617 (GRCm39) |
missense |
probably benign |
0.45 |
|
R1654:Mgam
|
UTSW |
6 |
40,734,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1667:Mgam
|
UTSW |
6 |
40,653,978 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1730:Mgam
|
UTSW |
6 |
40,641,794 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1781:Mgam
|
UTSW |
6 |
40,646,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1783:Mgam
|
UTSW |
6 |
40,641,794 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1829:Mgam
|
UTSW |
6 |
40,643,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1833:Mgam
|
UTSW |
6 |
40,631,652 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1872:Mgam
|
UTSW |
6 |
40,638,234 (GRCm39) |
nonsense |
probably null |
|
|
R1912:Mgam
|
UTSW |
6 |
40,741,119 (GRCm39) |
nonsense |
probably null |
|
|
R1977:Mgam
|
UTSW |
6 |
40,641,814 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2048:Mgam
|
UTSW |
6 |
40,633,363 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2086:Mgam
|
UTSW |
6 |
40,737,962 (GRCm39) |
splice site |
probably null |
|
|
R2138:Mgam
|
UTSW |
6 |
40,733,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2224:Mgam
|
UTSW |
6 |
40,741,208 (GRCm39) |
splice site |
probably null |
|
|
R2408:Mgam
|
UTSW |
6 |
40,663,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2508:Mgam
|
UTSW |
6 |
40,736,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2842:Mgam
|
UTSW |
6 |
40,638,279 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2847:Mgam
|
UTSW |
6 |
40,629,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R2848:Mgam
|
UTSW |
6 |
40,629,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R2965:Mgam
|
UTSW |
6 |
40,745,154 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R2966:Mgam
|
UTSW |
6 |
40,745,154 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3035:Mgam
|
UTSW |
6 |
40,640,464 (GRCm39) |
missense |
probably benign |
|
|
R3895:Mgam
|
UTSW |
6 |
40,736,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4027:Mgam
|
UTSW |
6 |
40,731,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4030:Mgam
|
UTSW |
6 |
40,731,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4302:Mgam
|
UTSW |
6 |
40,740,019 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4707:Mgam
|
UTSW |
6 |
40,691,566 (GRCm39) |
splice site |
probably null |
|
|
R4826:Mgam
|
UTSW |
6 |
40,657,582 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4898:Mgam
|
UTSW |
6 |
40,619,988 (GRCm39) |
missense |
probably benign |
|
|
R5438:Mgam
|
UTSW |
6 |
40,661,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5492:Mgam
|
UTSW |
6 |
40,733,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5770:Mgam
|
UTSW |
6 |
40,646,738 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5839:Mgam
|
UTSW |
6 |
40,716,998 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5845:Mgam
|
UTSW |
6 |
40,652,257 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R5847:Mgam
|
UTSW |
6 |
40,660,989 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5891:Mgam
|
UTSW |
6 |
40,721,282 (GRCm39) |
missense |
probably benign |
|
|
R6158:Mgam
|
UTSW |
6 |
40,734,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6193:Mgam
|
UTSW |
6 |
40,724,854 (GRCm39) |
nonsense |
probably null |
|
|
R6423:Mgam
|
UTSW |
6 |
40,653,979 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6706:Mgam
|
UTSW |
6 |
40,721,720 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6813:Mgam
|
UTSW |
6 |
40,727,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6863:Mgam
|
UTSW |
6 |
40,705,943 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6906:Mgam
|
UTSW |
6 |
40,724,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7091:Mgam
|
UTSW |
6 |
40,745,210 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7099:Mgam
|
UTSW |
6 |
40,638,650 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7282:Mgam
|
UTSW |
6 |
40,740,045 (GRCm39) |
missense |
probably benign |
|
|
R7282:Mgam
|
UTSW |
6 |
40,633,446 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7354:Mgam
|
UTSW |
6 |
40,721,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7374:Mgam
|
UTSW |
6 |
40,734,373 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7399:Mgam
|
UTSW |
6 |
40,643,788 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7406:Mgam
|
UTSW |
6 |
40,640,459 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7446:Mgam
|
UTSW |
6 |
40,723,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7466:Mgam
|
UTSW |
6 |
40,721,723 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7525:Mgam
|
UTSW |
6 |
40,742,954 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7530:Mgam
|
UTSW |
6 |
40,686,152 (GRCm39) |
splice site |
probably null |
|
|
R7570:Mgam
|
UTSW |
6 |
40,723,367 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7669:Mgam
|
UTSW |
6 |
40,635,944 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7679:Mgam
|
UTSW |
6 |
40,619,980 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7746:Mgam
|
UTSW |
6 |
40,645,127 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7859:Mgam
|
UTSW |
6 |
40,717,113 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7925:Mgam
|
UTSW |
6 |
40,735,985 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8206:Mgam
|
UTSW |
6 |
40,657,169 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8244:Mgam
|
UTSW |
6 |
40,727,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8309:Mgam
|
UTSW |
6 |
40,722,111 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8472:Mgam
|
UTSW |
6 |
40,671,460 (GRCm39) |
splice site |
probably null |
|
|
R8758:Mgam
|
UTSW |
6 |
40,705,977 (GRCm39) |
missense |
probably benign |
0.41 |
|
R8777:Mgam
|
UTSW |
6 |
40,632,185 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8777-TAIL:Mgam
|
UTSW |
6 |
40,632,185 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8783:Mgam
|
UTSW |
6 |
40,633,423 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8939:Mgam
|
UTSW |
6 |
40,740,137 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8968:Mgam
|
UTSW |
6 |
40,734,745 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8987:Mgam
|
UTSW |
6 |
40,706,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9055:Mgam
|
UTSW |
6 |
40,691,663 (GRCm39) |
intron |
probably benign |
|
|
R9171:Mgam
|
UTSW |
6 |
40,745,146 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9252:Mgam
|
UTSW |
6 |
40,706,577 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9258:Mgam
|
UTSW |
6 |
40,657,121 (GRCm39) |
missense |
probably benign |
|
|
R9262:Mgam
|
UTSW |
6 |
40,723,422 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9521:Mgam
|
UTSW |
6 |
40,722,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9589:Mgam
|
UTSW |
6 |
40,727,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9658:Mgam
|
UTSW |
6 |
40,721,311 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9784:Mgam
|
UTSW |
6 |
40,736,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF011:Mgam
|
UTSW |
6 |
40,734,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF020:Mgam
|
UTSW |
6 |
40,662,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF023:Mgam
|
UTSW |
6 |
40,657,642 (GRCm39) |
missense |
probably benign |
|
|
X0021:Mgam
|
UTSW |
6 |
40,635,981 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Mgam
|
UTSW |
6 |
40,619,994 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1176:Mgam
|
UTSW |
6 |
40,706,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Mgam
|
UTSW |
6 |
40,654,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Mgam
|
UTSW |
6 |
40,717,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGAAATCCATCATTGGTGTGTG -3'
(R):5'- AGAAAGCTGACATCATACCTTGG -3'
Sequencing Primer
(F):5'- TGCTTCTGCAGACAGGGG -3'
(R):5'- GACATCATACCTTGGTCCCAATGG -3'
|
| Posted On |
2022-03-25 |
Incidental Mutation