Incidental Mutation 'R9290:Myt1'
| ID |
704196 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myt1
|
| Ensembl Gene |
ENSMUSG00000010505 |
| Gene Name |
myelin transcription factor 1 |
| Synonyms |
NZF-2b, NZF-2a, Nztf2, Nzf2 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9290 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
181405125-181469590 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 181437667 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Leucine
at position 168
(H168L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000079900
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000081125]
[ENSMUST00000108756]
[ENSMUST00000108757]
[ENSMUST00000183403]
|
| AlphaFold |
Q8CFC2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000081125
AA Change: H168L
PolyPhen 2
Score 0.312 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000079900
Gene: ENSMUSG00000010505
AA Change: H168L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:zf-C2HC
|
71 |
99 |
8.7e-16 |
PFAM |
|
low complexity region
|
155 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
185 |
201 |
N/A |
INTRINSIC |
|
coiled coil region
|
300 |
354 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
405 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
485 |
512 |
2.9e-14 |
PFAM |
|
Pfam:zf-C2HC
|
529 |
557 |
4.3e-16 |
PFAM |
|
Pfam:MYT1
|
604 |
660 |
2e-28 |
PFAM |
|
Pfam:MYT1
|
659 |
835 |
2.3e-56 |
PFAM |
|
Pfam:zf-C2HC
|
843 |
871 |
2e-18 |
PFAM |
|
Pfam:zf-C2HC
|
887 |
915 |
1.9e-18 |
PFAM |
|
Pfam:zf-C2HC
|
936 |
964 |
2.1e-16 |
PFAM |
|
Pfam:zf-C2HC
|
989 |
1017 |
8.4e-16 |
PFAM |
|
coiled coil region
|
1037 |
1109 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108756
AA Change: H126L
PolyPhen 2
Score 0.087 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000104387
Gene: ENSMUSG00000010505
AA Change: H126L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:zf-C2HC
|
27 |
57 |
5.1e-18 |
PFAM |
|
low complexity region
|
113 |
118 |
N/A |
INTRINSIC |
|
low complexity region
|
143 |
159 |
N/A |
INTRINSIC |
|
coiled coil region
|
258 |
312 |
N/A |
INTRINSIC |
|
low complexity region
|
346 |
363 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
441 |
471 |
5e-17 |
PFAM |
|
Pfam:zf-C2HC
|
485 |
515 |
3.1e-18 |
PFAM |
|
Pfam:MYT1
|
562 |
618 |
2.4e-32 |
PFAM |
|
Pfam:MYT1
|
617 |
794 |
2e-74 |
PFAM |
|
Pfam:zf-C2HC
|
799 |
829 |
1.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
843 |
873 |
9.7e-20 |
PFAM |
|
Pfam:zf-C2HC
|
892 |
922 |
2.2e-18 |
PFAM |
|
Pfam:zf-C2HC
|
945 |
975 |
1.7e-16 |
PFAM |
|
coiled coil region
|
995 |
1067 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108757
AA Change: H126L
PolyPhen 2
Score 0.349 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000104388
Gene: ENSMUSG00000010505
AA Change: H126L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:zf-C2HC
|
27 |
57 |
1e-17 |
PFAM |
|
low complexity region
|
113 |
118 |
N/A |
INTRINSIC |
|
low complexity region
|
143 |
159 |
N/A |
INTRINSIC |
|
coiled coil region
|
258 |
312 |
N/A |
INTRINSIC |
|
low complexity region
|
346 |
363 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
441 |
471 |
1e-16 |
PFAM |
|
Pfam:zf-C2HC
|
485 |
510 |
6.2e-12 |
PFAM |
|
Pfam:MYT1
|
524 |
580 |
2.7e-32 |
PFAM |
|
Pfam:MYT1
|
579 |
756 |
2.3e-74 |
PFAM |
|
Pfam:zf-C2HC
|
761 |
791 |
3.8e-19 |
PFAM |
|
Pfam:zf-C2HC
|
805 |
835 |
1.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
854 |
884 |
4.3e-18 |
PFAM |
|
Pfam:zf-C2HC
|
907 |
937 |
3.3e-16 |
PFAM |
|
coiled coil region
|
957 |
1029 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129843
|
| SMART Domains |
Protein: ENSMUSP00000115697
Gene: ENSMUSG00000010505
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
50 |
67 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
147 |
174 |
6.2e-15 |
PFAM |
|
Pfam:zf-C2HC
|
191 |
219 |
9.2e-17 |
PFAM |
|
Pfam:MYT1
|
266 |
322 |
7.3e-29 |
PFAM |
|
Pfam:MYT1
|
321 |
497 |
7.2e-57 |
PFAM |
|
Pfam:zf-C2HC
|
505 |
533 |
9.6e-19 |
PFAM |
|
Pfam:zf-C2HC
|
554 |
582 |
4.4e-17 |
PFAM |
|
Pfam:zf-C2HC
|
607 |
635 |
1.8e-16 |
PFAM |
|
coiled coil region
|
654 |
726 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000122011
Gene: ENSMUSG00000010505
AA Change: H159L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:zf-C2HC
|
63 |
91 |
1.4e-16 |
PFAM |
|
low complexity region
|
147 |
152 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
177 |
204 |
4.6e-15 |
PFAM |
|
Pfam:zf-C2HC
|
221 |
249 |
6.7e-17 |
PFAM |
|
Pfam:MYT1
|
296 |
352 |
5.2e-29 |
PFAM |
|
Pfam:MYT1
|
351 |
527 |
4.5e-57 |
PFAM |
|
Pfam:zf-C2HC
|
535 |
556 |
1.4e-13 |
PFAM |
|
Pfam:zf-C2HC
|
556 |
584 |
3.5e-19 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000183403
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (67/68) |
| MGI Phenotype |
FUNCTION: This gene is a member of the myelin transcription factor 1 gene family. The encoded protein, a zinc finger DNA-binding protein, is involved in regulation of oligodendrocyte differentiation and proliferation in the developing central nervous system. The gene product has a role in remyelination through regeneration of oligodendrocyte lineage cells in response to demyelination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
PHENOTYPE: Mice homozygous for a knock-out allele die shortly after birth displaying improper diaphragm innervation and a failture to initiate breathing; mutant embryonic pancreata contain abnormal islet cells that express multiple hormones. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 68 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abl2 |
A |
G |
1: 156,457,538 (GRCm39) |
K268R |
probably damaging |
Het |
| Acvr1 |
T |
C |
2: 58,338,330 (GRCm39) |
D464G |
probably damaging |
Het |
| Adra1d |
G |
T |
2: 131,403,898 (GRCm39) |
T64K |
probably benign |
Het |
| Cct3 |
T |
C |
3: 88,216,536 (GRCm39) |
V164A |
probably benign |
Het |
| Cdhr2 |
T |
C |
13: 54,882,009 (GRCm39) |
V1153A |
possibly damaging |
Het |
| Cdkn2c |
A |
C |
4: 109,518,512 (GRCm39) |
Y147* |
probably null |
Het |
| Ces1g |
A |
T |
8: 94,029,545 (GRCm39) |
H562Q |
probably benign |
Het |
| Cfap221 |
A |
G |
1: 119,853,381 (GRCm39) |
L771P |
probably benign |
Het |
| Chsy3 |
A |
G |
18: 59,542,928 (GRCm39) |
M689V |
probably benign |
Het |
| Ciita |
T |
A |
16: 10,326,513 (GRCm39) |
S235T |
probably damaging |
Het |
| Cracdl |
T |
A |
1: 37,663,634 (GRCm39) |
R755W |
probably damaging |
Het |
| Dcdc2a |
A |
G |
13: 25,386,313 (GRCm39) |
K396E |
probably benign |
Het |
| Dgki |
C |
T |
6: 37,276,780 (GRCm39) |
C35Y |
unknown |
Het |
| Dnah11 |
C |
T |
12: 117,991,251 (GRCm39) |
E2372K |
probably damaging |
Het |
| Dnai7 |
T |
C |
6: 145,148,688 (GRCm39) |
E57G |
unknown |
Het |
| Eif3a |
A |
G |
19: 60,765,221 (GRCm39) |
V322A |
probably damaging |
Het |
| Foxp2 |
A |
T |
6: 15,197,120 (GRCm39) |
Q54L |
possibly damaging |
Het |
| Garin2 |
T |
A |
12: 78,759,028 (GRCm39) |
V116E |
possibly damaging |
Het |
| Gm19410 |
T |
A |
8: 36,269,386 (GRCm39) |
C1074S |
probably damaging |
Het |
| Gtf3c3 |
T |
G |
1: 54,477,997 (GRCm39) |
E26A |
possibly damaging |
Het |
| Hps5 |
T |
C |
7: 46,424,331 (GRCm39) |
E514G |
probably damaging |
Het |
| Ide |
A |
T |
19: 37,302,647 (GRCm39) |
D154E |
|
Het |
| Insm1 |
T |
C |
2: 146,065,273 (GRCm39) |
V363A |
probably benign |
Het |
| Iqgap2 |
A |
T |
13: 95,886,523 (GRCm39) |
M120K |
probably damaging |
Het |
| Kcnh5 |
T |
A |
12: 75,023,488 (GRCm39) |
I527F |
probably benign |
Het |
| Lrtm2 |
A |
G |
6: 119,297,792 (GRCm39) |
L83P |
probably damaging |
Het |
| Map1a |
A |
G |
2: 121,131,014 (GRCm39) |
E372G |
probably damaging |
Het |
| Mycbp2 |
A |
T |
14: 103,425,960 (GRCm39) |
H2421Q |
probably damaging |
Het |
| Myh15 |
A |
G |
16: 48,997,375 (GRCm39) |
E1731G |
probably damaging |
Het |
| Nxph4 |
A |
T |
10: 127,362,546 (GRCm39) |
V115E |
probably damaging |
Het |
| Ofcc1 |
A |
T |
13: 40,433,802 (GRCm39) |
I101N |
possibly damaging |
Het |
| Oog2 |
T |
C |
4: 143,923,015 (GRCm39) |
F427L |
probably benign |
Het |
| Or4c115 |
A |
G |
2: 88,928,076 (GRCm39) |
L65P |
probably damaging |
Het |
| Or4f14b |
A |
T |
2: 111,774,967 (GRCm39) |
I278N |
possibly damaging |
Het |
| Or5w11 |
A |
G |
2: 87,459,209 (GRCm39) |
N18S |
probably benign |
Het |
| Or8b48 |
T |
C |
9: 38,493,334 (GRCm39) |
S254P |
probably damaging |
Het |
| Or8g27 |
A |
G |
9: 39,129,531 (GRCm39) |
R293G |
probably damaging |
Het |
| Otop1 |
T |
G |
5: 38,455,302 (GRCm39) |
I232S |
probably benign |
Het |
| Pak6 |
G |
A |
2: 118,523,883 (GRCm39) |
R346Q |
probably damaging |
Het |
| Pbk |
A |
T |
14: 66,054,713 (GRCm39) |
M282L |
probably benign |
Het |
| Pmpcb |
T |
C |
5: 21,944,009 (GRCm39) |
|
probably null |
Het |
| Pou5f2 |
T |
A |
13: 78,173,585 (GRCm39) |
W176R |
probably damaging |
Het |
| Prkra |
G |
T |
2: 76,478,147 (GRCm39) |
S18R |
probably benign |
Het |
| Prune2 |
G |
T |
19: 17,145,691 (GRCm39) |
A2764S |
probably benign |
Het |
| Ptpdc1 |
A |
T |
13: 48,740,221 (GRCm39) |
D403E |
probably benign |
Het |
| Pxylp1 |
T |
C |
9: 96,722,089 (GRCm39) |
E54G |
probably damaging |
Het |
| Rap1gap |
G |
A |
4: 137,446,222 (GRCm39) |
A325T |
probably damaging |
Het |
| Raver2 |
G |
A |
4: 100,977,387 (GRCm39) |
|
probably benign |
Het |
| Rbpj |
T |
C |
5: 53,810,745 (GRCm39) |
V455A |
probably damaging |
Het |
| Rptor |
A |
T |
11: 119,702,823 (GRCm39) |
I397F |
probably benign |
Het |
| Sacs |
G |
A |
14: 61,421,499 (GRCm39) |
M148I |
probably benign |
Het |
| Sec16b |
A |
G |
1: 157,373,816 (GRCm39) |
Q496R |
probably damaging |
Het |
| Sned1 |
C |
A |
1: 93,199,385 (GRCm39) |
C488* |
probably null |
Het |
| Snupn |
G |
T |
9: 56,882,547 (GRCm39) |
V187F |
possibly damaging |
Het |
| Sorcs2 |
T |
C |
5: 36,183,225 (GRCm39) |
D1016G |
probably damaging |
Het |
| Spta1 |
T |
C |
1: 174,045,204 (GRCm39) |
M1517T |
possibly damaging |
Het |
| Them4 |
G |
T |
3: 94,231,630 (GRCm39) |
G156C |
probably damaging |
Het |
| Tnik |
T |
C |
3: 28,675,124 (GRCm39) |
S721P |
probably benign |
Het |
| Trpm8 |
T |
C |
1: 88,246,767 (GRCm39) |
S26P |
probably damaging |
Het |
| Ube2e3 |
A |
G |
2: 78,750,324 (GRCm39) |
I183M |
probably damaging |
Het |
| Uhrf2 |
A |
G |
19: 30,055,416 (GRCm39) |
Y389C |
probably damaging |
Het |
| Utp4 |
T |
A |
8: 107,642,828 (GRCm39) |
D495E |
possibly damaging |
Het |
| Vill |
C |
A |
9: 118,890,562 (GRCm39) |
N158K |
probably benign |
Het |
| Vmn1r219 |
G |
A |
13: 23,347,399 (GRCm39) |
G196E |
probably damaging |
Het |
| Vmn2r101 |
C |
T |
17: 19,811,395 (GRCm39) |
S493L |
probably benign |
Het |
| Vmn2r61 |
A |
G |
7: 41,915,385 (GRCm39) |
T111A |
probably benign |
Het |
| Zbtb40 |
G |
T |
4: 136,745,529 (GRCm39) |
A168E |
probably benign |
Het |
| Zscan18 |
A |
T |
7: 12,508,054 (GRCm39) |
I482N |
probably damaging |
Het |
|
| Other mutations in Myt1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00478:Myt1
|
APN |
2 |
181,442,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00816:Myt1
|
APN |
2 |
181,449,308 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01062:Myt1
|
APN |
2 |
181,439,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01069:Myt1
|
APN |
2 |
181,467,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01292:Myt1
|
APN |
2 |
181,446,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01521:Myt1
|
APN |
2 |
181,467,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01926:Myt1
|
APN |
2 |
181,463,790 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01976:Myt1
|
APN |
2 |
181,437,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02066:Myt1
|
APN |
2 |
181,438,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02109:Myt1
|
APN |
2 |
181,457,410 (GRCm39) |
splice site |
probably benign |
|
|
IGL02209:Myt1
|
APN |
2 |
181,439,027 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02499:Myt1
|
APN |
2 |
181,467,342 (GRCm39) |
splice site |
probably benign |
|
|
IGL03064:Myt1
|
APN |
2 |
181,439,594 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL03394:Myt1
|
APN |
2 |
181,439,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4366001:Myt1
|
UTSW |
2 |
181,467,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0003:Myt1
|
UTSW |
2 |
181,443,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0003:Myt1
|
UTSW |
2 |
181,443,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0362:Myt1
|
UTSW |
2 |
181,405,186 (GRCm39) |
unclassified |
probably benign |
|
|
R0627:Myt1
|
UTSW |
2 |
181,437,482 (GRCm39) |
missense |
probably benign |
0.10 |
|
R0650:Myt1
|
UTSW |
2 |
181,424,408 (GRCm39) |
nonsense |
probably null |
|
|
R0735:Myt1
|
UTSW |
2 |
181,449,180 (GRCm39) |
unclassified |
probably benign |
|
|
R0744:Myt1
|
UTSW |
2 |
181,439,298 (GRCm39) |
intron |
probably benign |
|
|
R1115:Myt1
|
UTSW |
2 |
181,453,024 (GRCm39) |
nonsense |
probably null |
|
|
R1460:Myt1
|
UTSW |
2 |
181,444,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1471:Myt1
|
UTSW |
2 |
181,438,904 (GRCm39) |
missense |
probably benign |
|
|
R1836:Myt1
|
UTSW |
2 |
181,439,068 (GRCm39) |
missense |
probably benign |
|
|
R1905:Myt1
|
UTSW |
2 |
181,439,549 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2007:Myt1
|
UTSW |
2 |
181,437,552 (GRCm39) |
missense |
probably benign |
|
|
R2040:Myt1
|
UTSW |
2 |
181,467,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Myt1
|
UTSW |
2 |
181,467,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2323:Myt1
|
UTSW |
2 |
181,448,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2926:Myt1
|
UTSW |
2 |
181,467,803 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R3895:Myt1
|
UTSW |
2 |
181,461,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4093:Myt1
|
UTSW |
2 |
181,453,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4649:Myt1
|
UTSW |
2 |
181,439,207 (GRCm39) |
missense |
probably benign |
|
|
R4693:Myt1
|
UTSW |
2 |
181,437,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4775:Myt1
|
UTSW |
2 |
181,464,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4835:Myt1
|
UTSW |
2 |
181,439,255 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5111:Myt1
|
UTSW |
2 |
181,437,678 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5120:Myt1
|
UTSW |
2 |
181,439,413 (GRCm39) |
missense |
probably benign |
0.25 |
|
R5622:Myt1
|
UTSW |
2 |
181,438,915 (GRCm39) |
missense |
probably benign |
|
|
R6457:Myt1
|
UTSW |
2 |
181,405,218 (GRCm39) |
splice site |
probably null |
|
|
R6704:Myt1
|
UTSW |
2 |
181,453,005 (GRCm39) |
start codon destroyed |
probably null |
|
|
R6752:Myt1
|
UTSW |
2 |
181,442,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6944:Myt1
|
UTSW |
2 |
181,439,387 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7337:Myt1
|
UTSW |
2 |
181,444,756 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7362:Myt1
|
UTSW |
2 |
181,439,033 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7368:Myt1
|
UTSW |
2 |
181,424,384 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7385:Myt1
|
UTSW |
2 |
181,409,498 (GRCm39) |
splice site |
probably null |
|
|
R7411:Myt1
|
UTSW |
2 |
181,456,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7593:Myt1
|
UTSW |
2 |
181,439,532 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7790:Myt1
|
UTSW |
2 |
181,439,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8035:Myt1
|
UTSW |
2 |
181,437,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8156:Myt1
|
UTSW |
2 |
181,464,554 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8338:Myt1
|
UTSW |
2 |
181,443,655 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8419:Myt1
|
UTSW |
2 |
181,424,399 (GRCm39) |
nonsense |
probably null |
|
|
R8553:Myt1
|
UTSW |
2 |
181,439,344 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9071:Myt1
|
UTSW |
2 |
181,448,420 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9144:Myt1
|
UTSW |
2 |
181,467,805 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9462:Myt1
|
UTSW |
2 |
181,467,729 (GRCm39) |
nonsense |
probably null |
|
|
R9502:Myt1
|
UTSW |
2 |
181,461,991 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9668:Myt1
|
UTSW |
2 |
181,452,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9700:Myt1
|
UTSW |
2 |
181,452,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF006:Myt1
|
UTSW |
2 |
181,439,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Myt1
|
UTSW |
2 |
181,449,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Myt1
|
UTSW |
2 |
181,438,955 (GRCm39) |
missense |
probably damaging |
0.97 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTCAGCTTACAGAGTTGCCC -3'
(R):5'- AAGCTGCACATGTCAGGAC -3'
Sequencing Primer
(F):5'- TGAGACTGAGCACCTGGTATC -3'
(R):5'- TGTCAGGACAAGACATTCCTTG -3'
|
| Posted On |
2022-03-25 |
Incidental Mutation