Mutagenetix > Incidental Mutation

Incidental Mutation 'R9300:Sdk2'

704883

Institutional Source

Beutler Lab

Gene Symbol

Sdk2

Ensembl Gene

ENSMUSG00000041592

Gene Name

sidekick cell adhesion molecule 2

Synonyms

5330435L01Rik, 4632412F08Rik

MMRRC Submission

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.072) question?

Stock #

R9300 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

113776374-114067046 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 113825030 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Arginine at position 1568 (W1568R)

Ref Sequence

ENSEMBL: ENSMUSP00000038972 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000041627]

AlphaFold

Q6V4S5

Predicted Effect

possibly damaging
Transcript: ENSMUST00000041627
AA Change: W1568R

PolyPhen 2 Score 0.635 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000038972
Gene: ENSMUSG00000041592
AA Change: W1568R

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
IGc2	43	102	4.67e-4	SMART
IG	123	208	6.07e-3	SMART
IG	225	309	1.4e-7	SMART
IGc2	325	391	6.21e-9	SMART
IGc2	418	486	8.57e-12	SMART
IG	506	591	2.37e-5	SMART
FN3	594	678	1.91e-7	SMART
FN3	694	780	2.42e-9	SMART
FN3	796	884	3.45e-5	SMART
FN3	899	981	2.36e-12	SMART
FN3	997	1084	1.64e-6	SMART
FN3	1101	1188	8.83e-12	SMART
FN3	1204	1289	3.62e-8	SMART
FN3	1305	1388	1.74e-10	SMART
FN3	1404	1489	8.23e-12	SMART
FN3	1506	1612	3.62e-8	SMART
FN3	1628	1713	1.15e-10	SMART
FN3	1728	1815	2.17e-11	SMART
FN3	1829	1913	5.04e-7	SMART
transmembrane domain	1935	1957	N/A	INTRINSIC
low complexity region	2138	2153	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired interconnectvity between VG3 amacrine cells and W3B retinal ganglion cells. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 88 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb1b	G	A	5: 8,825,614 (GRCm38)	V596I	probably benign	Het
Acad8	A	T	9: 26,977,632 (GRCm38)	H371Q	probably damaging	Het
Actn3	G	T	19: 4,871,628 (GRCm38)	R175S	probably benign	Het
Adamts9	G	T	6: 92,887,390 (GRCm38)	D780E	probably benign	Het
AK157302	C	A	13: 21,495,367 (GRCm38)	T21K	probably benign	Het
Ank3	A	T	10: 69,871,042 (GRCm38)	H329L	unknown	Het
Ankrd36	A	G	11: 5,569,979 (GRCm38)	H18R	possibly damaging	Het
Anks1b	T	A	10: 90,577,104 (GRCm38)	V38D	possibly damaging	Het
Apbb2	A	T	5: 66,313,334 (GRCm38)	L520H	probably damaging	Het
Arid1b	C	A	17: 5,242,999 (GRCm38)	P731T	probably damaging	Het
Atp1a4	A	G	1: 172,239,831 (GRCm38)	F578S	probably damaging	Het
Atp6v0a2	A	T	5: 124,712,248 (GRCm38)	I360F	probably damaging	Het
Bcas3	A	T	11: 85,557,358 (GRCm38)	I600F	probably damaging	Het
C1qtnf7	T	G	5: 43,609,099 (GRCm38)	C20W	possibly damaging	Het
Cadm1	A	T	9: 47,797,523 (GRCm38)	K184*	probably null	Het
Ccdc138	A	T	10: 58,507,626 (GRCm38)	H101L	probably benign	Het
Cep120	T	A	18: 53,719,297 (GRCm38)	N503I	probably damaging	Het
Chil4	T	C	3: 106,202,558 (GRCm38)	T380A	probably benign	Het
Clip2	A	G	5: 134,498,088 (GRCm38)		probably null	Het
Cyp3a11	G	A	5: 145,862,354 (GRCm38)	P341L	possibly damaging	Het
Cyp3a41a	G	C	5: 145,720,096 (GRCm38)		probably benign	Het
Dcaf1	A	G	9: 106,847,843 (GRCm38)	I509M	possibly damaging	Het
Dcaf13	T	C	15: 39,146,707 (GRCm38)	S429P	probably damaging	Het
Eln	A	G	5: 134,729,366 (GRCm38)	V151A	unknown	Het
Endou	T	G	15: 97,713,073 (GRCm38)	M377L	probably benign	Het
Etfa	A	G	9: 55,488,868 (GRCm38)	I138T	probably damaging	Het
Fbxw10	T	A	11: 62,877,283 (GRCm38)	S982T	probably benign	Het
Gm9602	A	T	14: 4,777,288 (GRCm38)	R47*	probably null	Het
Hectd4	G	A	5: 121,348,889 (GRCm38)	V3316I	probably benign	Het
Hif1a	T	C	12: 73,940,528 (GRCm38)	L477S	probably benign	Het
Icam5	G	C	9: 21,035,550 (GRCm38)	G458A	probably benign	Het
Itm2b	A	T	14: 73,366,456 (GRCm38)	D106E	probably benign	Het
Kdm4d	G	A	9: 14,464,040 (GRCm38)	T174M	probably damaging	Het
Kif16b	G	T	2: 142,699,287 (GRCm38)	D1364E	probably benign	Het
Lbhd1	G	A	19: 8,884,186 (GRCm38)	V61M	probably damaging	Het
Lclat1	T	A	17: 73,239,924 (GRCm38)	S279T	probably benign	Het
Lhx4	G	A	1: 155,705,210 (GRCm38)	L190F	probably damaging	Het
Lima1	C	T	15: 99,806,439 (GRCm38)	S283N	probably benign	Het
Magi1	C	A	6: 93,747,228 (GRCm38)	D496Y	probably damaging	Het
Map1a	T	C	2: 121,302,965 (GRCm38)	S1421P	probably damaging	Het
Map3k20	C	T	2: 72,371,913 (GRCm38)	H163Y	probably damaging	Het
Mier3	T	G	13: 111,686,356 (GRCm38)		probably null	Het
Mllt3	G	A	4: 87,774,047 (GRCm38)	Q560*	probably null	Het
Mmp25	T	A	17: 23,632,754 (GRCm38)	D327V	probably benign	Het
Nckap5	G	A	1: 125,981,686 (GRCm38)	Q1603*	probably null	Het
Nell1	G	A	7: 50,062,620 (GRCm38)	V63I	probably benign	Het
Or10al3	C	T	17: 37,700,924 (GRCm38)	P85S	probably damaging	Het
Or2ag2b	A	T	7: 106,818,904 (GRCm38)	I274F	probably benign	Het
Or8a1	A	C	9: 37,730,282 (GRCm38)	S234A	probably benign	Het
Pde12	C	T	14: 26,665,776 (GRCm38)	E526K	probably damaging	Het
Pfn4	T	C	12: 4,775,442 (GRCm38)	V93A	possibly damaging	Het
Poglut2	A	G	1: 44,117,202 (GRCm38)	I75T	possibly damaging	Het
Ppp2r3d	A	G	9: 124,423,977 (GRCm38)	S60P	unknown	Het
Prelp	T	C	1: 133,914,519 (GRCm38)	H296R	probably damaging	Het
Prickle1	T	C	15: 93,500,868 (GRCm38)	E693G	possibly damaging	Het
Rars1	A	G	11: 35,815,661 (GRCm38)	L477P	probably damaging	Het
Rasal1	G	A	5: 120,664,107 (GRCm38)	R328H	probably damaging	Het
Rasef	A	G	4: 73,741,156 (GRCm38)	F220S	probably benign	Het
Rif1	C	T	2: 52,111,139 (GRCm38)	S1535L	probably damaging	Het
Rnf17	T	C	14: 56,460,038 (GRCm38)	I463T	possibly damaging	Het
Ryr3	A	T	2: 112,860,350 (GRCm38)	D1138E	probably benign	Het
Scn9a	T	A	2: 66,504,892 (GRCm38)	Y1251F	probably benign	Het
Senp6	A	G	9: 80,142,151 (GRCm38)	E1019G	probably damaging	Het
Shh	A	G	5: 28,458,463 (GRCm38)	Y236H	probably damaging	Het
Sin3a	A	G	9: 57,107,460 (GRCm38)	D655G	probably damaging	Het
Slc35a4	C	T	18: 36,682,221 (GRCm38)	P35S	probably damaging	Het
Slc35g1	T	C	19: 38,396,185 (GRCm38)	L24P	probably benign	Het
Slc39a4	G	T	15: 76,614,559 (GRCm38)	Q312K	probably damaging	Het
Slc6a5	A	T	7: 49,951,427 (GRCm38)	I659F	probably damaging	Het
Slc7a4	T	C	16: 17,574,535 (GRCm38)	Y345C	probably benign	Het
Slco6c1	G	T	1: 97,066,084 (GRCm38)	R645S	probably benign	Het
Soat1	T	C	1: 156,441,353 (GRCm38)	Y209C	probably benign	Het
Tbc1d9b	T	C	11: 50,163,887 (GRCm38)	S953P	probably benign	Het
Tgm1	G	A	14: 55,704,846 (GRCm38)	H683Y	probably benign	Het
Tmem98	G	A	11: 80,817,606 (GRCm38)	R134Q	probably damaging	Het
Trpm3	A	C	19: 22,978,381 (GRCm38)	M1107L	possibly damaging	Het
Vmn1r11	G	A	6: 57,137,887 (GRCm38)	V179I	probably benign	Het
Vmn1r119	G	T	7: 21,011,713 (GRCm38)	T248K	probably damaging	Het
Vmn1r236	T	A	17: 21,286,683 (GRCm38)	I21N	possibly damaging	Het
Vmn2r24	A	G	6: 123,816,071 (GRCm38)	T786A	possibly damaging	Het
Vstm5	A	T	9: 15,257,289 (GRCm38)	I50F	probably damaging	Het
Wdr1	T	C	5: 38,527,912 (GRCm38)	D572G	probably damaging	Het
Xaf1	T	C	11: 72,301,691 (GRCm38)	F5S	probably benign	Het
Zan	A	T	5: 137,470,257 (GRCm38)		probably null	Het
Zfp697	T	C	3: 98,427,663 (GRCm38)	V248A	possibly damaging	Het
Zftraf1	C	A	15: 76,646,341 (GRCm38)	V260L	probably benign	Het
Zkscan3	T	A	13: 21,393,497 (GRCm38)	T249S	unknown	Het
Znfx1	A	G	2: 167,055,940 (GRCm38)	Y355H	probably damaging	Het

Other mutations in Sdk2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00972:Sdk2	APN	11	113,854,384 (GRCm38)	missense	possibly damaging	0.86
IGL01063:Sdk2	APN	11	113,830,842 (GRCm38)	missense	probably damaging	1.00
IGL01291:Sdk2	APN	11	113,843,080 (GRCm38)	missense	probably benign
IGL01316:Sdk2	APN	11	113,867,965 (GRCm38)	missense	probably benign	0.09
IGL01614:Sdk2	APN	11	113,793,858 (GRCm38)	missense	probably damaging	1.00
IGL01998:Sdk2	APN	11	113,838,532 (GRCm38)	missense	probably damaging	0.98
IGL02014:Sdk2	APN	11	113,838,494 (GRCm38)	missense	probably damaging	1.00
IGL02095:Sdk2	APN	11	113,834,830 (GRCm38)	missense	probably damaging	1.00
IGL02115:Sdk2	APN	11	113,834,813 (GRCm38)	splice site	probably benign
IGL02543:Sdk2	APN	11	113,868,921 (GRCm38)	missense	possibly damaging	0.90
IGL02976:Sdk2	APN	11	113,851,842 (GRCm38)	missense	probably damaging	1.00
IGL03001:Sdk2	APN	11	113,821,626 (GRCm38)	missense	probably benign	0.00
IGL03122:Sdk2	APN	11	113,842,068 (GRCm38)	missense	probably damaging	1.00
IGL03183:Sdk2	APN	11	113,850,984 (GRCm38)	missense	probably benign	0.19
IGL03222:Sdk2	APN	11	113,838,431 (GRCm38)	missense	probably benign	0.01
IGL03310:Sdk2	APN	11	113,793,325 (GRCm38)	missense	possibly damaging	0.77
Curtailed	UTSW	11	113,851,800 (GRCm38)	missense	probably damaging	1.00
Trimmed	UTSW	11	113,856,696 (GRCm38)	nonsense	probably null
ANU05:Sdk2	UTSW	11	113,843,080 (GRCm38)	missense	probably benign
BB008:Sdk2	UTSW	11	113,893,441 (GRCm38)	missense	possibly damaging	0.79
BB018:Sdk2	UTSW	11	113,893,441 (GRCm38)	missense	possibly damaging	0.79
R0008:Sdk2	UTSW	11	113,856,755 (GRCm38)	missense	probably damaging	1.00
R0008:Sdk2	UTSW	11	113,856,755 (GRCm38)	missense	probably damaging	1.00
R0088:Sdk2	UTSW	11	113,827,086 (GRCm38)	missense	possibly damaging	0.74
R0096:Sdk2	UTSW	11	113,903,144 (GRCm38)	splice site	probably benign
R0386:Sdk2	UTSW	11	113,893,464 (GRCm38)	missense	probably damaging	0.96
R0396:Sdk2	UTSW	11	113,829,967 (GRCm38)	missense	probably benign	0.04
R0409:Sdk2	UTSW	11	113,850,891 (GRCm38)	splice site	probably benign
R0416:Sdk2	UTSW	11	113,803,203 (GRCm38)	missense	probably damaging	1.00
R0456:Sdk2	UTSW	11	113,791,466 (GRCm38)	missense	possibly damaging	0.93
R0544:Sdk2	UTSW	11	113,781,010 (GRCm38)	missense	probably damaging	1.00
R0691:Sdk2	UTSW	11	113,794,920 (GRCm38)	splice site	probably null
R0711:Sdk2	UTSW	11	113,903,144 (GRCm38)	splice site	probably benign
R0717:Sdk2	UTSW	11	113,832,326 (GRCm38)	missense	probably damaging	1.00
R0780:Sdk2	UTSW	11	113,893,508 (GRCm38)	missense	probably benign	0.07
R0831:Sdk2	UTSW	11	113,832,258 (GRCm38)	missense	probably damaging	0.96
R0853:Sdk2	UTSW	11	113,821,415 (GRCm38)	missense	probably benign	0.00
R0865:Sdk2	UTSW	11	113,850,922 (GRCm38)	missense	probably benign	0.12
R0930:Sdk2	UTSW	11	113,838,445 (GRCm38)	missense	probably benign	0.01
R0964:Sdk2	UTSW	11	113,806,417 (GRCm38)	splice site	probably benign
R1051:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1052:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1054:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1055:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1077:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1079:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1115:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1186:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1187:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1337:Sdk2	UTSW	11	113,832,331 (GRCm38)	missense	possibly damaging	0.79
R1430:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1433:Sdk2	UTSW	11	113,795,045 (GRCm38)	missense	probably damaging	0.99
R1464:Sdk2	UTSW	11	113,830,080 (GRCm38)	missense	possibly damaging	0.86
R1464:Sdk2	UTSW	11	113,830,080 (GRCm38)	missense	possibly damaging	0.86
R1497:Sdk2	UTSW	11	113,893,575 (GRCm38)	splice site	probably benign
R1514:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1529:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1596:Sdk2	UTSW	11	113,838,609 (GRCm38)	splice site	probably benign
R1680:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1680:Sdk2	UTSW	11	113,791,436 (GRCm38)	missense	possibly damaging	0.47
R1770:Sdk2	UTSW	11	113,793,741 (GRCm38)	missense	probably benign	0.05
R1858:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1866:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1874:Sdk2	UTSW	11	113,834,956 (GRCm38)	missense	probably benign	0.00
R1899:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1905:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1907:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1913:Sdk2	UTSW	11	113,856,726 (GRCm38)	missense	possibly damaging	0.77
R1964:Sdk2	UTSW	11	113,781,017 (GRCm38)	nonsense	probably null
R2055:Sdk2	UTSW	11	113,850,954 (GRCm38)	missense	probably damaging	1.00
R2059:Sdk2	UTSW	11	113,854,332 (GRCm38)	missense	probably damaging	1.00
R2093:Sdk2	UTSW	11	113,943,122 (GRCm38)	missense	probably damaging	1.00
R2256:Sdk2	UTSW	11	113,830,794 (GRCm38)	missense	probably benign	0.44
R3720:Sdk2	UTSW	11	113,800,244 (GRCm38)	missense	probably damaging	1.00
R3795:Sdk2	UTSW	11	113,856,696 (GRCm38)	nonsense	probably null
R4037:Sdk2	UTSW	11	113,795,055 (GRCm38)	missense	probably damaging	1.00
R4171:Sdk2	UTSW	11	113,866,989 (GRCm38)	splice site	probably null
R4717:Sdk2	UTSW	11	113,854,369 (GRCm38)	missense	probably damaging	0.96
R4758:Sdk2	UTSW	11	113,827,054 (GRCm38)	missense	possibly damaging	0.87
R4857:Sdk2	UTSW	11	113,821,382 (GRCm38)	nonsense	probably null
R4924:Sdk2	UTSW	11	113,857,758 (GRCm38)	missense	probably damaging	1.00
R5015:Sdk2	UTSW	11	113,793,761 (GRCm38)	missense	probably damaging	1.00
R5171:Sdk2	UTSW	11	113,850,982 (GRCm38)	missense	probably benign	0.01
R5239:Sdk2	UTSW	11	113,868,033 (GRCm38)	missense	probably damaging	1.00
R5243:Sdk2	UTSW	11	113,825,086 (GRCm38)	missense	possibly damaging	0.76
R5279:Sdk2	UTSW	11	113,867,031 (GRCm38)	missense	probably benign	0.31
R5535:Sdk2	UTSW	11	113,943,158 (GRCm38)	missense	possibly damaging	0.80
R5634:Sdk2	UTSW	11	113,851,714 (GRCm38)	missense	probably damaging	1.00
R5637:Sdk2	UTSW	11	113,833,179 (GRCm38)	missense	probably damaging	1.00
R5726:Sdk2	UTSW	11	113,851,800 (GRCm38)	missense	probably damaging	1.00
R5793:Sdk2	UTSW	11	113,868,952 (GRCm38)	missense	possibly damaging	0.46
R5798:Sdk2	UTSW	11	113,827,116 (GRCm38)	missense	probably damaging	1.00
R5834:Sdk2	UTSW	11	113,854,273 (GRCm38)	missense	probably damaging	1.00
R5863:Sdk2	UTSW	11	113,834,984 (GRCm38)	missense	probably damaging	0.98
R5869:Sdk2	UTSW	11	113,851,882 (GRCm38)	missense	probably damaging	0.96
R5875:Sdk2	UTSW	11	113,830,059 (GRCm38)	missense	probably benign	0.00
R5953:Sdk2	UTSW	11	113,793,744 (GRCm38)	missense	probably damaging	1.00
R5991:Sdk2	UTSW	11	113,943,254 (GRCm38)	missense	probably damaging	0.97
R6018:Sdk2	UTSW	11	113,830,063 (GRCm38)	missense	probably benign	0.00
R6116:Sdk2	UTSW	11	113,854,364 (GRCm38)	missense	probably damaging	0.99
R6328:Sdk2	UTSW	11	113,793,755 (GRCm38)	missense	probably damaging	1.00
R6348:Sdk2	UTSW	11	113,893,508 (GRCm38)	missense	probably benign	0.07
R6383:Sdk2	UTSW	11	113,832,265 (GRCm38)	missense	probably damaging	1.00
R6824:Sdk2	UTSW	11	113,867,934 (GRCm38)	missense	probably benign	0.43
R6835:Sdk2	UTSW	11	113,830,048 (GRCm38)	missense	probably damaging	0.98
R6853:Sdk2	UTSW	11	113,780,929 (GRCm38)	missense	probably damaging	0.99
R6912:Sdk2	UTSW	11	113,903,120 (GRCm38)	missense	probably benign	0.03
R7000:Sdk2	UTSW	11	113,803,169 (GRCm38)	missense	probably damaging	1.00
R7099:Sdk2	UTSW	11	113,834,905 (GRCm38)	missense	probably damaging	0.98
R7102:Sdk2	UTSW	11	113,842,690 (GRCm38)	nonsense	probably null
R7177:Sdk2	UTSW	11	113,829,969 (GRCm38)	missense	possibly damaging	0.91
R7381:Sdk2	UTSW	11	113,838,489 (GRCm38)	missense	probably damaging	0.98
R7412:Sdk2	UTSW	11	113,868,083 (GRCm38)	splice site	probably null
R7504:Sdk2	UTSW	11	113,867,967 (GRCm38)	missense	possibly damaging	0.50
R7552:Sdk2	UTSW	11	113,873,213 (GRCm38)	missense	possibly damaging	0.63
R7604:Sdk2	UTSW	11	113,829,969 (GRCm38)	missense	possibly damaging	0.91
R7647:Sdk2	UTSW	11	113,793,737 (GRCm38)	missense	probably damaging	1.00
R7897:Sdk2	UTSW	11	113,873,201 (GRCm38)	missense	possibly damaging	0.50
R7931:Sdk2	UTSW	11	113,893,441 (GRCm38)	missense	possibly damaging	0.79
R7998:Sdk2	UTSW	11	113,859,938 (GRCm38)	missense	probably benign	0.18
R8052:Sdk2	UTSW	11	113,854,351 (GRCm38)	missense	probably damaging	1.00
R8053:Sdk2	UTSW	11	113,854,351 (GRCm38)	missense	probably damaging	1.00
R8084:Sdk2	UTSW	11	113,827,089 (GRCm38)	missense	possibly damaging	0.67
R8136:Sdk2	UTSW	11	113,851,713 (GRCm38)	missense	probably damaging	1.00
R8151:Sdk2	UTSW	11	113,872,857 (GRCm38)	missense	possibly damaging	0.84
R8394:Sdk2	UTSW	11	113,838,716 (GRCm38)	missense	probably benign
R8715:Sdk2	UTSW	11	113,780,902 (GRCm38)	missense	probably damaging	1.00
R8774:Sdk2	UTSW	11	113,839,343 (GRCm38)	missense	probably damaging	1.00
R8774-TAIL:Sdk2	UTSW	11	113,839,343 (GRCm38)	missense	probably damaging	1.00
R8804:Sdk2	UTSW	11	113,873,152 (GRCm38)	nonsense	probably null
R9136:Sdk2	UTSW	11	113,806,377 (GRCm38)	missense	probably damaging	1.00
R9147:Sdk2	UTSW	11	113,823,400 (GRCm38)	missense	probably benign	0.18
R9354:Sdk2	UTSW	11	113,834,931 (GRCm38)	missense	probably benign	0.00
R9450:Sdk2	UTSW	11	113,806,279 (GRCm38)	missense	probably benign
R9462:Sdk2	UTSW	11	113,869,918 (GRCm38)	missense	possibly damaging	0.56
R9616:Sdk2	UTSW	11	113,800,235 (GRCm38)	missense	probably benign	0.05
R9678:Sdk2	UTSW	11	113,794,963 (GRCm38)	nonsense	probably null
RF002:Sdk2	UTSW	11	113,885,252 (GRCm38)	missense	probably benign	0.00
V1662:Sdk2	UTSW	11	113,834,908 (GRCm38)	missense	probably damaging	1.00
Z1176:Sdk2	UTSW	11	113,851,836 (GRCm38)	missense	probably damaging	0.97
Z1176:Sdk2	UTSW	11	113,839,322 (GRCm38)	missense	probably benign	0.41
Z1177:Sdk2	UTSW	11	113,859,956 (GRCm38)	missense	probably benign
Z1177:Sdk2	UTSW	11	113,839,320 (GRCm38)	missense	probably damaging	1.00
Z1177:Sdk2	UTSW	11	113,838,659 (GRCm38)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- CATTGACATCTACCTCAGGGC -3'
(R):5'- GAGTGAGGTGAGCCATAGTC -3'

Sequencing Primer
(F):5'- TAACTACTGCTGTGCCCAGAGTG -3'
(R):5'- TGAGCCATAGTCAAGGCCC -3'

Posted On

2022-03-25