Incidental Mutation 'R9328:Ccdc180'
| ID |
706630 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ccdc180
|
| Ensembl Gene |
ENSMUSG00000035539 |
| Gene Name |
coiled-coil domain containing 180 |
| Synonyms |
LOC381522, E230008N13Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9328 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
45890303-45950774 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 45902447 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 292
(N292S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136714
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000178561]
|
| AlphaFold |
J3QNE4 |
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000119784
Gene: ENSMUSG00000035539
AA Change: N284S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
42 |
N/A |
INTRINSIC |
|
coiled coil region
|
90 |
117 |
N/A |
INTRINSIC |
|
Pfam:DUF4455
|
141 |
609 |
2e-189 |
PFAM |
|
low complexity region
|
628 |
642 |
N/A |
INTRINSIC |
|
low complexity region
|
658 |
675 |
N/A |
INTRINSIC |
|
coiled coil region
|
710 |
780 |
N/A |
INTRINSIC |
|
coiled coil region
|
945 |
979 |
N/A |
INTRINSIC |
|
low complexity region
|
1100 |
1123 |
N/A |
INTRINSIC |
|
Pfam:DUF4456
|
1169 |
1372 |
9.5e-77 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000178561
AA Change: N292S
PolyPhen 2
Score 0.707 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000136714
Gene: ENSMUSG00000035539
AA Change: N292S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
49 |
N/A |
INTRINSIC |
|
coiled coil region
|
98 |
125 |
N/A |
INTRINSIC |
|
Pfam:DUF4455
|
148 |
616 |
7.3e-189 |
PFAM |
|
low complexity region
|
635 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
665 |
682 |
N/A |
INTRINSIC |
|
coiled coil region
|
718 |
788 |
N/A |
INTRINSIC |
|
coiled coil region
|
1121 |
1155 |
N/A |
INTRINSIC |
|
low complexity region
|
1275 |
1298 |
N/A |
INTRINSIC |
|
Pfam:DUF4456
|
1344 |
1547 |
2.2e-76 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a coiled-coil domain. Alternative splicing results in multiple transcript variants encoding different isoforms. A single nucleotide polymorphism (SNP) in this gene has been associated with increased susceptibility to Behcet's Disease (PMID: 19442274). [provided by RefSeq, Dec 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1600014C10Rik |
A |
G |
7: 37,894,272 (GRCm39) |
T102A |
probably benign |
Het |
| 1700109H08Rik |
A |
G |
5: 3,632,161 (GRCm39) |
K164E |
possibly damaging |
Het |
| 2610042L04Rik |
C |
T |
14: 4,350,013 (GRCm38) |
Q74* |
probably null |
Het |
| Aadacl4fm4 |
T |
A |
4: 144,401,256 (GRCm39) |
H76L |
probably benign |
Het |
| Adgrb2 |
T |
A |
4: 129,915,363 (GRCm39) |
M1381K |
probably damaging |
Het |
| Adgrv1 |
C |
A |
13: 81,620,523 (GRCm39) |
D3975Y |
probably damaging |
Het |
| Ano10 |
C |
T |
9: 122,090,168 (GRCm39) |
E382K |
possibly damaging |
Het |
| Ascc3 |
T |
C |
10: 50,535,015 (GRCm39) |
V636A |
probably damaging |
Het |
| AU040320 |
T |
C |
4: 126,729,332 (GRCm39) |
V498A |
possibly damaging |
Het |
| Bahcc1 |
C |
T |
11: 120,165,885 (GRCm39) |
T1047I |
possibly damaging |
Het |
| BC004004 |
A |
T |
17: 29,501,682 (GRCm39) |
T74S |
possibly damaging |
Het |
| Bend3 |
A |
G |
10: 43,387,419 (GRCm39) |
D604G |
possibly damaging |
Het |
| Brinp3 |
T |
A |
1: 146,707,455 (GRCm39) |
V373E |
probably damaging |
Het |
| Bsph2 |
A |
T |
7: 13,290,764 (GRCm39) |
D38E |
probably benign |
Het |
| Castor1 |
T |
C |
11: 4,170,423 (GRCm39) |
F140L |
probably benign |
Het |
| Catsperd |
A |
G |
17: 56,965,074 (GRCm39) |
I474V |
possibly damaging |
Het |
| Cd1d1 |
A |
T |
3: 86,905,459 (GRCm39) |
V178E |
possibly damaging |
Het |
| Cdca2 |
T |
A |
14: 67,931,131 (GRCm39) |
R521W |
probably damaging |
Het |
| Champ1 |
A |
G |
8: 13,929,392 (GRCm39) |
K517E |
probably damaging |
Het |
| Chrna9 |
T |
C |
5: 66,128,569 (GRCm39) |
F259S |
probably damaging |
Het |
| Chuk |
A |
T |
19: 44,085,422 (GRCm39) |
C241* |
probably null |
Het |
| Clns1a |
A |
G |
7: 97,363,240 (GRCm39) |
Y204C |
probably benign |
Het |
| Cplane1 |
A |
G |
15: 8,215,692 (GRCm39) |
D416G |
probably damaging |
Het |
| Cyp2j7 |
A |
T |
4: 96,115,869 (GRCm39) |
N192K |
probably damaging |
Het |
| Ddr2 |
A |
G |
1: 169,829,504 (GRCm39) |
V250A |
probably benign |
Het |
| Dlgap2 |
A |
G |
8: 14,777,441 (GRCm39) |
S229G |
probably damaging |
Het |
| Dmrt1 |
A |
T |
19: 25,523,231 (GRCm39) |
H194L |
probably damaging |
Het |
| Dock7 |
A |
T |
4: 98,968,064 (GRCm39) |
F138I |
|
Het |
| Dsg2 |
T |
C |
18: 20,715,847 (GRCm39) |
V263A |
possibly damaging |
Het |
| Dusp16 |
A |
G |
6: 134,716,902 (GRCm39) |
L135P |
probably damaging |
Het |
| Dysf |
A |
G |
6: 84,050,895 (GRCm39) |
N414S |
probably damaging |
Het |
| Efhc1 |
A |
G |
1: 21,030,598 (GRCm39) |
Y177C |
probably damaging |
Het |
| Fam83e |
A |
T |
7: 45,372,912 (GRCm39) |
R174S |
probably benign |
Het |
| Fgf4 |
C |
T |
7: 144,416,664 (GRCm39) |
L199F |
probably damaging |
Het |
| Fignl2 |
A |
G |
15: 100,951,271 (GRCm39) |
L337P |
unknown |
Het |
| Gm4353 |
T |
C |
7: 115,682,724 (GRCm39) |
R286G |
probably damaging |
Het |
| Gm5142 |
T |
C |
14: 59,416,126 (GRCm39) |
S11G |
probably benign |
Het |
| Gpr151 |
A |
G |
18: 42,712,270 (GRCm39) |
V136A |
probably damaging |
Het |
| Ift80 |
T |
A |
3: 68,847,483 (GRCm39) |
I338F |
probably damaging |
Het |
| Itgb4 |
A |
G |
11: 115,880,625 (GRCm39) |
S693G |
probably benign |
Het |
| Kif13a |
T |
A |
13: 46,951,838 (GRCm39) |
I812F |
probably damaging |
Het |
| Krit1 |
T |
C |
5: 3,862,577 (GRCm39) |
|
probably null |
Het |
| Mapk6 |
T |
C |
9: 75,305,252 (GRCm39) |
D55G |
possibly damaging |
Het |
| Matn3 |
A |
G |
12: 9,002,033 (GRCm39) |
I82V |
possibly damaging |
Het |
| Mecom |
T |
A |
3: 30,063,994 (GRCm39) |
D32V |
unknown |
Het |
| Nacad |
T |
C |
11: 6,552,417 (GRCm39) |
H258R |
possibly damaging |
Het |
| Ndufaf5 |
T |
A |
2: 140,030,752 (GRCm39) |
S213T |
possibly damaging |
Het |
| Nphp1 |
C |
T |
2: 127,582,892 (GRCm39) |
D674N |
possibly damaging |
Het |
| Nsmaf |
A |
G |
4: 6,426,412 (GRCm39) |
L250P |
probably damaging |
Het |
| Ogdh |
T |
C |
11: 6,297,838 (GRCm39) |
S571P |
probably benign |
Het |
| Or1e31 |
T |
C |
11: 73,690,478 (GRCm39) |
Y35C |
probably damaging |
Het |
| Or51i2 |
T |
A |
7: 103,689,268 (GRCm39) |
D88E |
|
Het |
| Or8g27 |
T |
C |
9: 39,129,175 (GRCm39) |
I174T |
probably damaging |
Het |
| Osbpl11 |
A |
G |
16: 33,047,245 (GRCm39) |
I403V |
probably damaging |
Het |
| Peg10 |
CCACATCAGGATCCACATCAGGATGCACATCAGCATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAG |
CCACATCAGGATCCACATCAGGATGCACATCAG |
6: 4,756,398 (GRCm39) |
|
probably benign |
Het |
| Pira13 |
T |
A |
7: 3,827,580 (GRCm39) |
R192S |
unknown |
Het |
| Plat |
A |
G |
8: 23,268,133 (GRCm39) |
R300G |
probably damaging |
Het |
| Ppid |
T |
C |
3: 79,505,059 (GRCm39) |
I134T |
probably damaging |
Het |
| Rad51ap2 |
A |
G |
12: 11,507,772 (GRCm39) |
I565V |
probably benign |
Het |
| Rasa1 |
T |
C |
13: 85,403,575 (GRCm39) |
|
probably null |
Het |
| Sema4a |
C |
T |
3: 88,345,613 (GRCm39) |
W490* |
probably null |
Het |
| Septin3 |
A |
G |
15: 82,173,439 (GRCm39) |
Y257C |
probably damaging |
Het |
| Sh3rf2 |
C |
A |
18: 42,274,161 (GRCm39) |
F442L |
probably benign |
Het |
| Sipa1l1 |
A |
G |
12: 82,388,792 (GRCm39) |
I339M |
possibly damaging |
Het |
| Six2 |
T |
C |
17: 85,995,196 (GRCm39) |
N62S |
possibly damaging |
Het |
| Slc44a5 |
T |
C |
3: 153,964,678 (GRCm39) |
I526T |
probably benign |
Het |
| Smarca5 |
T |
C |
8: 81,447,378 (GRCm39) |
S402G |
probably benign |
Het |
| Son |
T |
A |
16: 91,452,645 (GRCm39) |
V464E |
possibly damaging |
Het |
| Sorcs3 |
A |
G |
19: 48,785,950 (GRCm39) |
K1144E |
probably damaging |
Het |
| Stxbp6 |
A |
G |
12: 44,902,659 (GRCm39) |
L204P |
probably damaging |
Het |
| Tchh |
A |
G |
3: 93,351,570 (GRCm39) |
R337G |
unknown |
Het |
| Tgm4 |
T |
C |
9: 122,885,697 (GRCm39) |
V413A |
possibly damaging |
Het |
| Tmem131 |
G |
A |
1: 36,858,236 (GRCm39) |
Q704* |
probably null |
Het |
| Tmpo |
T |
C |
10: 90,998,825 (GRCm39) |
K321E |
probably damaging |
Het |
| Trim75 |
G |
T |
8: 65,435,315 (GRCm39) |
N378K |
probably benign |
Het |
| Tspan18 |
T |
A |
2: 93,036,065 (GRCm39) |
I227F |
probably benign |
Het |
| Ttn |
C |
T |
2: 76,541,526 (GRCm39) |
W33820* |
probably null |
Het |
| Urb2 |
T |
A |
8: 124,774,034 (GRCm39) |
Y1522N |
probably damaging |
Het |
| Zbtb40 |
T |
C |
4: 136,745,620 (GRCm39) |
N138D |
probably benign |
Het |
| Zfp715 |
A |
T |
7: 42,947,328 (GRCm39) |
H877Q |
possibly damaging |
Het |
|
| Other mutations in Ccdc180 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01369:Ccdc180
|
APN |
4 |
45,900,256 (GRCm39) |
missense |
probably benign |
|
|
IGL01713:Ccdc180
|
APN |
4 |
45,921,025 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01915:Ccdc180
|
APN |
4 |
45,904,544 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01935:Ccdc180
|
APN |
4 |
45,906,889 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02539:Ccdc180
|
APN |
4 |
45,921,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02982:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
IGL03071:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
IGL03146:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
PIT4687001:Ccdc180
|
UTSW |
4 |
45,949,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0049:Ccdc180
|
UTSW |
4 |
45,930,119 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0049:Ccdc180
|
UTSW |
4 |
45,930,119 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0054:Ccdc180
|
UTSW |
4 |
45,890,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0054:Ccdc180
|
UTSW |
4 |
45,890,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0080:Ccdc180
|
UTSW |
4 |
45,896,205 (GRCm39) |
missense |
probably null |
0.00 |
|
R0082:Ccdc180
|
UTSW |
4 |
45,896,205 (GRCm39) |
missense |
probably null |
0.00 |
|
R0126:Ccdc180
|
UTSW |
4 |
45,912,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0193:Ccdc180
|
UTSW |
4 |
45,914,803 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0276:Ccdc180
|
UTSW |
4 |
45,923,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0362:Ccdc180
|
UTSW |
4 |
45,923,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0380:Ccdc180
|
UTSW |
4 |
45,930,197 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0468:Ccdc180
|
UTSW |
4 |
45,923,271 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0539:Ccdc180
|
UTSW |
4 |
45,922,010 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0543:Ccdc180
|
UTSW |
4 |
45,900,041 (GRCm39) |
nonsense |
probably null |
|
|
R0546:Ccdc180
|
UTSW |
4 |
45,904,597 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R0612:Ccdc180
|
UTSW |
4 |
45,927,969 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0792:Ccdc180
|
UTSW |
4 |
45,927,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1056:Ccdc180
|
UTSW |
4 |
45,916,375 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1099:Ccdc180
|
UTSW |
4 |
45,914,225 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1136:Ccdc180
|
UTSW |
4 |
45,914,589 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1263:Ccdc180
|
UTSW |
4 |
45,903,887 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1331:Ccdc180
|
UTSW |
4 |
45,909,359 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1522:Ccdc180
|
UTSW |
4 |
45,927,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1819:Ccdc180
|
UTSW |
4 |
45,926,195 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R2022:Ccdc180
|
UTSW |
4 |
45,944,418 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2056:Ccdc180
|
UTSW |
4 |
45,932,477 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2219:Ccdc180
|
UTSW |
4 |
45,944,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2228:Ccdc180
|
UTSW |
4 |
45,948,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2229:Ccdc180
|
UTSW |
4 |
45,948,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2255:Ccdc180
|
UTSW |
4 |
45,921,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2427:Ccdc180
|
UTSW |
4 |
45,929,545 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3001:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3002:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3003:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3110:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3111:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3112:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3898:Ccdc180
|
UTSW |
4 |
45,912,799 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4022:Ccdc180
|
UTSW |
4 |
45,904,560 (GRCm39) |
nonsense |
probably null |
|
|
R4084:Ccdc180
|
UTSW |
4 |
45,950,632 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4377:Ccdc180
|
UTSW |
4 |
45,941,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4595:Ccdc180
|
UTSW |
4 |
45,945,023 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4637:Ccdc180
|
UTSW |
4 |
45,914,443 (GRCm39) |
missense |
probably benign |
|
|
R4811:Ccdc180
|
UTSW |
4 |
45,928,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Ccdc180
|
UTSW |
4 |
45,912,794 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4858:Ccdc180
|
UTSW |
4 |
45,923,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4888:Ccdc180
|
UTSW |
4 |
45,909,308 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4940:Ccdc180
|
UTSW |
4 |
45,917,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4940:Ccdc180
|
UTSW |
4 |
45,917,453 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5042:Ccdc180
|
UTSW |
4 |
45,916,255 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5119:Ccdc180
|
UTSW |
4 |
45,914,603 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5177:Ccdc180
|
UTSW |
4 |
45,917,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5311:Ccdc180
|
UTSW |
4 |
45,917,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5333:Ccdc180
|
UTSW |
4 |
45,890,935 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5448:Ccdc180
|
UTSW |
4 |
45,920,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5510:Ccdc180
|
UTSW |
4 |
45,928,046 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6018:Ccdc180
|
UTSW |
4 |
45,926,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6108:Ccdc180
|
UTSW |
4 |
45,911,389 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6283:Ccdc180
|
UTSW |
4 |
45,902,486 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6483:Ccdc180
|
UTSW |
4 |
45,921,950 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6618:Ccdc180
|
UTSW |
4 |
45,950,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7017:Ccdc180
|
UTSW |
4 |
45,940,934 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7205:Ccdc180
|
UTSW |
4 |
45,914,588 (GRCm39) |
missense |
probably benign |
|
|
R7341:Ccdc180
|
UTSW |
4 |
45,898,644 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7351:Ccdc180
|
UTSW |
4 |
45,903,887 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7418:Ccdc180
|
UTSW |
4 |
45,904,616 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7492:Ccdc180
|
UTSW |
4 |
45,930,009 (GRCm39) |
splice site |
probably null |
|
|
R7573:Ccdc180
|
UTSW |
4 |
45,922,015 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7639:Ccdc180
|
UTSW |
4 |
45,928,043 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7792:Ccdc180
|
UTSW |
4 |
45,890,389 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7806:Ccdc180
|
UTSW |
4 |
45,912,801 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7812:Ccdc180
|
UTSW |
4 |
45,906,952 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7840:Ccdc180
|
UTSW |
4 |
45,900,461 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7842:Ccdc180
|
UTSW |
4 |
45,909,428 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8712:Ccdc180
|
UTSW |
4 |
45,920,842 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8818:Ccdc180
|
UTSW |
4 |
45,900,484 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8961:Ccdc180
|
UTSW |
4 |
45,929,573 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R8983:Ccdc180
|
UTSW |
4 |
45,909,359 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9035:Ccdc180
|
UTSW |
4 |
45,906,922 (GRCm39) |
nonsense |
probably null |
|
|
R9095:Ccdc180
|
UTSW |
4 |
45,949,466 (GRCm39) |
nonsense |
probably null |
|
|
R9240:Ccdc180
|
UTSW |
4 |
45,917,566 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9293:Ccdc180
|
UTSW |
4 |
45,944,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9346:Ccdc180
|
UTSW |
4 |
45,927,953 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9521:Ccdc180
|
UTSW |
4 |
45,916,283 (GRCm39) |
missense |
probably null |
0.50 |
|
R9653:Ccdc180
|
UTSW |
4 |
45,923,495 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9667:Ccdc180
|
UTSW |
4 |
45,920,861 (GRCm39) |
nonsense |
probably null |
|
|
X0017:Ccdc180
|
UTSW |
4 |
45,909,350 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
Z1176:Ccdc180
|
UTSW |
4 |
45,920,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Ccdc180
|
UTSW |
4 |
45,916,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAAGACCTCTGGCAAAGTGG -3'
(R):5'- TCCAGGAAGAGTCAGTGGTG -3'
Sequencing Primer
(F):5'- AAAGTGGTCCTCTGCACG -3'
(R):5'- CCTGGAACTCACTTTGTAGATCAGG -3'
|
| Posted On |
2022-04-18 |
Incidental Mutation