Incidental Mutation 'R9334:Neurl4'
| ID |
707013 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Neurl4
|
| Ensembl Gene |
ENSMUSG00000047284 |
| Gene Name |
neuralized E3 ubiquitin protein ligase 4 |
| Synonyms |
0610025P10Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9334 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
69792545-69804648 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 69796792 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Serine
at position 518
(R518S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000135277
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000061837]
[ENSMUST00000108617]
[ENSMUST00000129475]
[ENSMUST00000133203]
[ENSMUST00000144431]
[ENSMUST00000177138]
[ENSMUST00000177476]
|
| AlphaFold |
Q5NCX5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000061837
AA Change: R540S
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000053235
Gene: ENSMUSG00000047284
AA Change: R540S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
44 |
N/A |
INTRINSIC |
|
NEUZ
|
47 |
165 |
1.02e-28 |
SMART |
|
low complexity region
|
207 |
237 |
N/A |
INTRINSIC |
|
NEUZ
|
317 |
442 |
7.22e-52 |
SMART |
|
low complexity region
|
492 |
503 |
N/A |
INTRINSIC |
|
NEUZ
|
520 |
644 |
6.15e-46 |
SMART |
|
low complexity region
|
686 |
700 |
N/A |
INTRINSIC |
|
NEUZ
|
716 |
840 |
7.81e-39 |
SMART |
|
NEUZ
|
913 |
1043 |
2.27e-17 |
SMART |
|
low complexity region
|
1108 |
1117 |
N/A |
INTRINSIC |
|
NEUZ
|
1130 |
1250 |
4.93e-6 |
SMART |
|
low complexity region
|
1453 |
1464 |
N/A |
INTRINSIC |
|
low complexity region
|
1474 |
1483 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108617
AA Change: R518S
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000104257
Gene: ENSMUSG00000047284
AA Change: R518S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
44 |
N/A |
INTRINSIC |
|
NEUZ
|
47 |
165 |
3.5e-31 |
SMART |
|
low complexity region
|
207 |
237 |
N/A |
INTRINSIC |
|
NEUZ
|
295 |
420 |
2.5e-54 |
SMART |
|
low complexity region
|
470 |
481 |
N/A |
INTRINSIC |
|
NEUZ
|
498 |
622 |
2e-48 |
SMART |
|
low complexity region
|
664 |
678 |
N/A |
INTRINSIC |
|
NEUZ
|
694 |
818 |
2.6e-41 |
SMART |
|
NEUZ
|
891 |
1021 |
7.6e-20 |
SMART |
|
low complexity region
|
1086 |
1095 |
N/A |
INTRINSIC |
|
NEUZ
|
1108 |
1228 |
1.7e-8 |
SMART |
|
low complexity region
|
1431 |
1442 |
N/A |
INTRINSIC |
|
low complexity region
|
1452 |
1461 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000129475
AA Change: R217S
PolyPhen 2
Score 0.942 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000135733
Gene: ENSMUSG00000047284
AA Change: R217S
| Domain | Start | End | E-Value | Type |
|---|
|
NEUZ
|
1 |
119 |
4.22e-44 |
SMART |
|
low complexity region
|
169 |
180 |
N/A |
INTRINSIC |
|
low complexity region
|
182 |
201 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
206 |
246 |
1.46e-10 |
PROSPERO |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000133203
AA Change: R283S
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000117917
Gene: ENSMUSG00000047284
AA Change: R283S
| Domain | Start | End | E-Value | Type |
|---|
|
NEUZ
|
60 |
185 |
7.22e-52 |
SMART |
|
low complexity region
|
235 |
246 |
N/A |
INTRINSIC |
|
NEUZ
|
263 |
387 |
6.15e-46 |
SMART |
|
low complexity region
|
429 |
443 |
N/A |
INTRINSIC |
|
NEUZ
|
459 |
583 |
7.81e-39 |
SMART |
|
NEUZ
|
656 |
786 |
2.27e-17 |
SMART |
|
low complexity region
|
851 |
860 |
N/A |
INTRINSIC |
|
Pfam:Neuralized
|
875 |
942 |
6.5e-10 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144431
|
| SMART Domains |
Protein: ENSMUSP00000135926
Gene: ENSMUSG00000018570
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
86 |
108 |
N/A |
INTRINSIC |
|
low complexity region
|
115 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
132 |
144 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000177138
AA Change: R518S
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000135277
Gene: ENSMUSG00000047284
AA Change: R518S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
44 |
N/A |
INTRINSIC |
|
NEUZ
|
47 |
165 |
1.02e-28 |
SMART |
|
low complexity region
|
207 |
237 |
N/A |
INTRINSIC |
|
NEUZ
|
295 |
420 |
7.22e-52 |
SMART |
|
low complexity region
|
470 |
481 |
N/A |
INTRINSIC |
|
NEUZ
|
498 |
622 |
6.15e-46 |
SMART |
|
low complexity region
|
664 |
678 |
N/A |
INTRINSIC |
|
NEUZ
|
694 |
818 |
7.81e-39 |
SMART |
|
NEUZ
|
889 |
1019 |
2.27e-17 |
SMART |
|
low complexity region
|
1084 |
1093 |
N/A |
INTRINSIC |
|
NEUZ
|
1106 |
1226 |
4.93e-6 |
SMART |
|
low complexity region
|
1429 |
1440 |
N/A |
INTRINSIC |
|
low complexity region
|
1450 |
1459 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000177476
AA Change: R540S
PolyPhen 2
Score 0.982 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000135185
Gene: ENSMUSG00000047284
AA Change: R540S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
44 |
N/A |
INTRINSIC |
|
NEUZ
|
47 |
165 |
1.02e-28 |
SMART |
|
low complexity region
|
207 |
237 |
N/A |
INTRINSIC |
|
NEUZ
|
317 |
442 |
7.22e-52 |
SMART |
|
low complexity region
|
492 |
503 |
N/A |
INTRINSIC |
|
NEUZ
|
520 |
644 |
6.15e-46 |
SMART |
|
low complexity region
|
686 |
700 |
N/A |
INTRINSIC |
|
NEUZ
|
716 |
840 |
7.81e-39 |
SMART |
|
NEUZ
|
911 |
1041 |
2.27e-17 |
SMART |
|
low complexity region
|
1106 |
1115 |
N/A |
INTRINSIC |
|
NEUZ
|
1128 |
1248 |
4.93e-6 |
SMART |
|
low complexity region
|
1451 |
1462 |
N/A |
INTRINSIC |
|
low complexity region
|
1472 |
1481 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is predicted and it includes two isoforms resulting from two alternatively spliced transcript variants. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actr1b |
A |
T |
1: 36,739,251 (GRCm39) |
I346N |
probably damaging |
Het |
| Adam6b |
A |
C |
12: 113,454,768 (GRCm39) |
E528D |
probably damaging |
Het |
| Ang |
A |
G |
14: 51,339,017 (GRCm39) |
M53V |
possibly damaging |
Het |
| Ankrd26 |
G |
A |
6: 118,509,262 (GRCm39) |
A601V |
probably benign |
Het |
| Atp6v0d2 |
A |
G |
4: 19,890,695 (GRCm39) |
L155P |
probably damaging |
Het |
| Cacna1a |
T |
C |
8: 85,296,594 (GRCm39) |
V1204A |
probably damaging |
Het |
| Car4 |
A |
G |
11: 84,855,415 (GRCm39) |
I183V |
probably benign |
Het |
| Ccdc149 |
G |
T |
5: 52,578,171 (GRCm39) |
A87E |
possibly damaging |
Het |
| Ccdc88b |
A |
G |
19: 6,833,541 (GRCm39) |
M208T |
possibly damaging |
Het |
| Ccnt2 |
T |
C |
1: 127,723,046 (GRCm39) |
L162S |
probably damaging |
Het |
| Cd27 |
A |
G |
6: 125,213,718 (GRCm39) |
|
probably null |
Het |
| Cfap44 |
C |
A |
16: 44,239,654 (GRCm39) |
T567K |
probably damaging |
Het |
| Cpne5 |
C |
T |
17: 29,423,673 (GRCm39) |
V152M |
probably benign |
Het |
| Cyp2u1 |
C |
T |
3: 131,092,065 (GRCm39) |
V152M |
probably damaging |
Het |
| Dnajc13 |
A |
T |
9: 104,051,659 (GRCm39) |
F1733I |
probably benign |
Het |
| Dop1a |
A |
G |
9: 86,403,027 (GRCm39) |
Y1409C |
probably damaging |
Het |
| Ecm2 |
T |
C |
13: 49,677,815 (GRCm39) |
M367T |
probably benign |
Het |
| Eif4g2 |
A |
G |
7: 110,674,031 (GRCm39) |
S658P |
possibly damaging |
Het |
| Exoc3l4 |
T |
C |
12: 111,397,117 (GRCm39) |
L666P |
probably damaging |
Het |
| Fbxl4 |
G |
A |
4: 22,376,778 (GRCm39) |
M71I |
probably damaging |
Het |
| Fbxw10 |
T |
C |
11: 62,765,910 (GRCm39) |
S727P |
possibly damaging |
Het |
| Fem1b |
A |
T |
9: 62,703,604 (GRCm39) |
L552* |
probably null |
Het |
| Filip1 |
A |
T |
9: 79,725,739 (GRCm39) |
V960D |
probably benign |
Het |
| Glipr1l3 |
A |
T |
10: 111,979,948 (GRCm39) |
M198K |
probably benign |
Het |
| Gm19410 |
T |
A |
8: 36,270,722 (GRCm39) |
C1216* |
probably null |
Het |
| Gmps |
T |
A |
3: 63,889,864 (GRCm39) |
V81E |
probably damaging |
Het |
| Gpr150 |
G |
T |
13: 76,204,103 (GRCm39) |
Q281K |
probably benign |
Het |
| Grsf1 |
A |
G |
5: 88,820,469 (GRCm39) |
V221A |
probably damaging |
Het |
| Gsc |
T |
A |
12: 104,439,353 (GRCm39) |
I8F |
probably damaging |
Het |
| Homer2 |
A |
T |
7: 81,261,078 (GRCm39) |
C284* |
probably null |
Het |
| Hrg |
T |
A |
16: 22,780,061 (GRCm39) |
H446Q |
unknown |
Het |
| Jag1 |
C |
T |
2: 136,943,593 (GRCm39) |
R201H |
probably damaging |
Het |
| Kctd15 |
C |
T |
7: 34,341,483 (GRCm39) |
R148H |
possibly damaging |
Het |
| Klhdc7a |
G |
A |
4: 139,693,493 (GRCm39) |
R485C |
probably benign |
Het |
| Ldhd |
T |
A |
8: 112,353,980 (GRCm39) |
I407F |
probably benign |
Het |
| Lgals12 |
G |
A |
19: 7,578,086 (GRCm39) |
R192C |
probably benign |
Het |
| Lmf2 |
G |
A |
15: 89,239,577 (GRCm39) |
L26F |
probably damaging |
Het |
| Lum |
A |
T |
10: 97,404,347 (GRCm39) |
I81F |
probably damaging |
Het |
| Map1b |
G |
T |
13: 99,568,148 (GRCm39) |
D1524E |
unknown |
Het |
| Marveld3 |
A |
G |
8: 110,675,036 (GRCm39) |
L260S |
probably damaging |
Het |
| Mms19 |
C |
T |
19: 41,942,203 (GRCm39) |
R555H |
probably benign |
Het |
| Mrpl37 |
G |
A |
4: 106,921,605 (GRCm39) |
T208I |
probably benign |
Het |
| Mug1 |
A |
T |
6: 121,838,490 (GRCm39) |
T498S |
probably benign |
Het |
| Myo3b |
T |
C |
2: 70,047,360 (GRCm39) |
C289R |
probably damaging |
Het |
| Myo7a |
A |
T |
7: 97,716,369 (GRCm39) |
F1459Y |
probably damaging |
Het |
| Nmnat2 |
T |
G |
1: 152,949,585 (GRCm39) |
V43G |
probably damaging |
Het |
| Or2b11 |
T |
C |
11: 59,462,272 (GRCm39) |
Y98C |
probably damaging |
Het |
| Or2n1b |
T |
A |
17: 38,459,840 (GRCm39) |
F120L |
probably benign |
Het |
| Or6c6c |
A |
G |
10: 129,541,683 (GRCm39) |
N312S |
probably benign |
Het |
| Otog |
A |
G |
7: 45,909,353 (GRCm39) |
T608A |
possibly damaging |
Het |
| Pck2 |
G |
A |
14: 55,785,283 (GRCm39) |
R482Q |
probably damaging |
Het |
| Pcx |
G |
A |
19: 4,670,532 (GRCm39) |
M1013I |
probably benign |
Het |
| Pex13 |
A |
G |
11: 23,605,630 (GRCm39) |
M200T |
probably benign |
Het |
| Pigt |
CCGTGCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGTGCCCGTGGTGTACCCCCTCTCTAGTCCTGTGAGCCCGTGGTGTACCCCCTCTCTAGTCCGGCGCGCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGCGCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGAGCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGAGCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGTGCCCGTGGTGTACCCCCTCTCTAGTCCTGTGAGCCCGTGGTGTACCCCCTCTCTAGTCCGGCGCGCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGCTCCCATGGTGTGCCCCCTCTCTAGTCCGGCGCTCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGAGCCCGTGGTGTGCCCCCTCTCTAGTCC |
CCGTGCCCGTGGTGTACCCCCTCTCTAGTCCTGTGAGCCCGTGGTGTACCCCCTCTCTAGTCCGGCGCGCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGCGCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGAGCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGAGCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGTGCCCGTGGTGTACCCCCTCTCTAGTCCTGTGAGCCCGTGGTGTACCCCCTCTCTAGTCCGGCGCGCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGCTCCCATGGTGTGCCCCCTCTCTAGTCCGGCGCTCCCGTGGTGTGCCCCCTCTCTAGTCCGGCGAGCCCGTGGTGTGCCCCCTCTCTAGTCC |
2: 164,349,420 (GRCm39) |
|
probably null |
Het |
| Pramel32 |
A |
T |
4: 88,548,186 (GRCm39) |
I73K |
probably damaging |
Het |
| Ptpn4 |
T |
C |
1: 119,730,114 (GRCm39) |
H26R |
probably benign |
Het |
| Ralgps2 |
T |
A |
1: 156,715,599 (GRCm39) |
E72V |
probably damaging |
Het |
| Relch |
T |
A |
1: 105,654,179 (GRCm39) |
F873L |
possibly damaging |
Het |
| Scube1 |
A |
T |
15: 83,512,264 (GRCm39) |
C396S |
possibly damaging |
Het |
| Sec23b |
T |
A |
2: 144,410,550 (GRCm39) |
N283K |
possibly damaging |
Het |
| Setx |
T |
A |
2: 29,044,032 (GRCm39) |
Y1800* |
probably null |
Het |
| Sgce |
G |
T |
6: 4,707,205 (GRCm39) |
S213R |
probably damaging |
Het |
| Skic3 |
C |
A |
13: 76,281,076 (GRCm39) |
T704N |
possibly damaging |
Het |
| Slc36a2 |
T |
C |
11: 55,075,865 (GRCm39) |
|
probably benign |
Het |
| Sult5a1 |
A |
T |
8: 123,875,146 (GRCm39) |
D129E |
probably damaging |
Het |
| Tacr1 |
A |
T |
6: 82,380,913 (GRCm39) |
H108L |
probably damaging |
Het |
| Tnfsf10 |
T |
A |
3: 27,389,496 (GRCm39) |
Y186N |
probably damaging |
Het |
| Unc80 |
T |
C |
1: 66,688,919 (GRCm39) |
S2428P |
possibly damaging |
Het |
| Vwf |
G |
A |
6: 125,654,909 (GRCm39) |
R2535H |
|
Het |
| Zfp532 |
A |
G |
18: 65,756,128 (GRCm39) |
I20M |
probably damaging |
Het |
|
| Other mutations in Neurl4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00339:Neurl4
|
APN |
11 |
69,795,413 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00516:Neurl4
|
APN |
11 |
69,801,219 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01409:Neurl4
|
APN |
11 |
69,797,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01951:Neurl4
|
APN |
11 |
69,800,449 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02056:Neurl4
|
APN |
11 |
69,796,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02206:Neurl4
|
APN |
11 |
69,801,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02557:Neurl4
|
APN |
11 |
69,797,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02878:Neurl4
|
APN |
11 |
69,797,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0022:Neurl4
|
UTSW |
11 |
69,799,891 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
PIT4377001:Neurl4
|
UTSW |
11 |
69,801,232 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0388:Neurl4
|
UTSW |
11 |
69,802,559 (GRCm39) |
splice site |
probably benign |
|
|
R0421:Neurl4
|
UTSW |
11 |
69,799,360 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0449:Neurl4
|
UTSW |
11 |
69,796,393 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1174:Neurl4
|
UTSW |
11 |
69,794,547 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1345:Neurl4
|
UTSW |
11 |
69,794,702 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1536:Neurl4
|
UTSW |
11 |
69,794,252 (GRCm39) |
nonsense |
probably null |
|
|
R1642:Neurl4
|
UTSW |
11 |
69,794,485 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1857:Neurl4
|
UTSW |
11 |
69,796,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1935:Neurl4
|
UTSW |
11 |
69,797,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1936:Neurl4
|
UTSW |
11 |
69,797,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1967:Neurl4
|
UTSW |
11 |
69,794,036 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1973:Neurl4
|
UTSW |
11 |
69,800,118 (GRCm39) |
missense |
probably benign |
|
|
R2046:Neurl4
|
UTSW |
11 |
69,799,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2165:Neurl4
|
UTSW |
11 |
69,794,047 (GRCm39) |
missense |
probably benign |
|
|
R2393:Neurl4
|
UTSW |
11 |
69,797,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3810:Neurl4
|
UTSW |
11 |
69,794,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4299:Neurl4
|
UTSW |
11 |
69,799,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4749:Neurl4
|
UTSW |
11 |
69,801,894 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4898:Neurl4
|
UTSW |
11 |
69,793,997 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4968:Neurl4
|
UTSW |
11 |
69,798,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4969:Neurl4
|
UTSW |
11 |
69,801,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5503:Neurl4
|
UTSW |
11 |
69,797,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6655:Neurl4
|
UTSW |
11 |
69,801,742 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6791:Neurl4
|
UTSW |
11 |
69,799,336 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7029:Neurl4
|
UTSW |
11 |
69,801,562 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7216:Neurl4
|
UTSW |
11 |
69,801,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7361:Neurl4
|
UTSW |
11 |
69,802,905 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7367:Neurl4
|
UTSW |
11 |
69,799,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7804:Neurl4
|
UTSW |
11 |
69,796,700 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7871:Neurl4
|
UTSW |
11 |
69,794,012 (GRCm39) |
missense |
probably benign |
|
|
R8092:Neurl4
|
UTSW |
11 |
69,801,891 (GRCm39) |
missense |
probably benign |
|
|
R8121:Neurl4
|
UTSW |
11 |
69,799,056 (GRCm39) |
splice site |
probably null |
|
|
R8131:Neurl4
|
UTSW |
11 |
69,800,067 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8289:Neurl4
|
UTSW |
11 |
69,800,206 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8354:Neurl4
|
UTSW |
11 |
69,800,062 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8494:Neurl4
|
UTSW |
11 |
69,801,871 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8529:Neurl4
|
UTSW |
11 |
69,799,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8850:Neurl4
|
UTSW |
11 |
69,794,788 (GRCm39) |
unclassified |
probably benign |
|
|
R8992:Neurl4
|
UTSW |
11 |
69,798,958 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9509:Neurl4
|
UTSW |
11 |
69,792,971 (GRCm39) |
nonsense |
probably null |
|
|
R9705:Neurl4
|
UTSW |
11 |
69,799,679 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9707:Neurl4
|
UTSW |
11 |
69,799,679 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9746:Neurl4
|
UTSW |
11 |
69,798,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0025:Neurl4
|
UTSW |
11 |
69,797,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Neurl4
|
UTSW |
11 |
69,794,916 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCAGTGAAAGTGACCATCG -3'
(R):5'- GAGTGTGTCAAGGCTTAAACTAG -3'
Sequencing Primer
(F):5'- TGAAAGTGACCATCGTCCATAATAAC -3'
(R):5'- GGAATATTAGTCTGATACCCACTGCC -3'
|
| Posted On |
2022-04-18 |
Incidental Mutation