Mutagenetix > Incidental Mutation

Incidental Mutation 'R9338:Pkd1l3'

707309

Institutional Source

Beutler Lab

Gene Symbol

Pkd1l3

Ensembl Gene

ENSMUSG00000048827

Gene Name

polycystic kidney disease 1 like 3

Synonyms

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R9338 (G1)

Quality Score

214.458

Status

Not validated

Chromosome

Chromosomal Location

109614517-109674386 bp(+) (GRCm38)

Type of Mutation

small deletion (13 aa in frame mutation)

DNA Base Change (assembly)

GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA to GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA at 109624195 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000148592 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057344] [ENSMUST00000109242] [ENSMUST00000212537]

AlphaFold

Q2EG98

Predicted Effect

probably benign
Transcript: ENSMUST00000057344

SMART Domains

Protein: ENSMUSP00000051512
Gene: ENSMUSG00000048827

Domain	Start	End	E-Value	Type
signal peptide	1	20	N/A	INTRINSIC
CLECT	26	142	4.25e-1	SMART
internal_repeat_2	143	245	2.25e-8	PROSPERO
low complexity region	246	270	N/A	INTRINSIC
low complexity region	272	296	N/A	INTRINSIC
low complexity region	298	322	N/A	INTRINSIC
low complexity region	324	348	N/A	INTRINSIC
internal_repeat_1	349	431	1.22e-8	PROSPERO
internal_repeat_2	378	466	2.25e-8	PROSPERO
internal_repeat_1	518	731	1.22e-8	PROSPERO
GPS	1007	1056	3.62e-5	SMART
transmembrane domain	1075	1094	N/A	INTRINSIC
LH2	1119	1238	1.01e-9	SMART
transmembrane domain	1282	1304	N/A	INTRINSIC
transmembrane domain	1319	1341	N/A	INTRINSIC
low complexity region	1398	1408	N/A	INTRINSIC
low complexity region	1451	1460	N/A	INTRINSIC
low complexity region	1484	1497	N/A	INTRINSIC
transmembrane domain	1534	1556	N/A	INTRINSIC
transmembrane domain	1576	1595	N/A	INTRINSIC
Pfam:PKD_channel	1695	2110	2.8e-86	PFAM
Pfam:Ion_trans	1858	2114	2.9e-9	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000109242

SMART Domains

Protein: ENSMUSP00000104865
Gene: ENSMUSG00000048827

Domain	Start	End	E-Value	Type
signal peptide	1	20	N/A	INTRINSIC
CLECT	26	142	4.25e-1	SMART
internal_repeat_2	143	245	2.63e-8	PROSPERO
low complexity region	246	270	N/A	INTRINSIC
low complexity region	272	296	N/A	INTRINSIC
low complexity region	298	322	N/A	INTRINSIC
low complexity region	324	348	N/A	INTRINSIC
internal_repeat_1	349	440	3.96e-14	PROSPERO
internal_repeat_2	378	466	2.63e-8	PROSPERO
internal_repeat_1	518	724	3.96e-14	PROSPERO
GPS	1017	1066	3.62e-5	SMART
transmembrane domain	1085	1104	N/A	INTRINSIC
LH2	1129	1248	1.01e-9	SMART
transmembrane domain	1292	1314	N/A	INTRINSIC
transmembrane domain	1329	1351	N/A	INTRINSIC
low complexity region	1408	1418	N/A	INTRINSIC
low complexity region	1461	1470	N/A	INTRINSIC
low complexity region	1494	1507	N/A	INTRINSIC
transmembrane domain	1544	1566	N/A	INTRINSIC
transmembrane domain	1586	1605	N/A	INTRINSIC
Pfam:PKD_channel	1705	2120	1.3e-86	PFAM
Pfam:Ion_trans	1868	2124	4.3e-9	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000212537

Meta Mutation Damage Score

0.0846

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 98.8%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores.[provided by RefSeq, Apr 2009]
PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and grossly normal and exhibit normal taste responsiveness in various behavioral and electrophysiological tests of taste function. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 59 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb9	T	C	5: 124,090,113 (GRCm38)	T22A	possibly damaging	Het
Adam30	G	A	3: 98,162,813 (GRCm38)	G654D	probably damaging	Het
Cct3	T	C	3: 88,318,399 (GRCm38)	V343A	probably benign	Het
Col11a2	A	G	17: 34,047,230 (GRCm38)	T358A	unknown	Het
Cox6a2	T	C	7: 128,205,742 (GRCm38)	Y94C	probably damaging	Het
Cubn	T	A	2: 13,381,892 (GRCm38)	I1521F	probably damaging	Het
Dclk3	C	A	9: 111,439,305 (GRCm38)	A14E	unknown	Het
Dlgap2	T	C	8: 14,179,683 (GRCm38)		probably null	Het
Dop1b	C	A	16: 93,803,560 (GRCm38)	Q2042K	probably damaging	Het
Ech1	A	G	7: 28,826,002 (GRCm38)	S61G	probably null	Het
Ext2	T	A	2: 93,696,258 (GRCm38)	N678Y	probably damaging	Het
Fgfr2	G	T	7: 130,261,831 (GRCm38)	C28*	probably null	Het
Gon4l	C	A	3: 88,901,712 (GRCm38)	D1754E	probably benign	Het
Hivep2	T	A	10: 14,128,949 (GRCm38)	C430*	probably null	Het
Htr7	C	T	19: 35,964,380 (GRCm38)		probably null	Het
Idh3b	A	T	2: 130,280,472 (GRCm38)	M331K	probably damaging	Het
Ighv2-7	A	T	12: 113,807,498 (GRCm38)	F56I	probably benign	Het
Inpp5k	C	T	11: 75,645,585 (GRCm38)	H330Y	probably damaging	Het
Kif26b	T	C	1: 178,916,493 (GRCm38)	Y1385H	probably damaging	Het
Mad1l1	A	G	5: 140,088,806 (GRCm38)	L543P	probably damaging	Het
Mdn1	A	T	4: 32,666,536 (GRCm38)	H158L	probably benign	Het
Mpp2	T	A	11: 102,060,423 (GRCm38)	T511S	probably benign	Het
Msantd5f6	T	C	4: 73,402,008 (GRCm38)	E178G	possibly damaging	Het
Msh4	T	C	3: 153,867,807 (GRCm38)	I737V	possibly damaging	Het
Myo15b	T	C	11: 115,871,412 (GRCm38)	L1186P		Het
Nckap1l	A	G	15: 103,471,564 (GRCm38)	T346A	probably benign	Het
Nox4	G	A	7: 87,376,240 (GRCm38)	R525Q	probably benign	Het
Npy5r	T	C	8: 66,682,006 (GRCm38)	N45S	probably benign	Het
Or6c202	T	C	10: 129,160,741 (GRCm38)	N81S	probably benign	Het
Pde6a	G	A	18: 61,221,037 (GRCm38)	A145T	probably damaging	Het
Pfkp	A	C	13: 6,584,688 (GRCm38)	S678A	probably damaging	Het
Phxr2	A	G	10: 99,126,181 (GRCm38)		probably benign	Het
Pi4ka	C	A	16: 17,317,363 (GRCm38)	L942F		Het
Pla2g4e	T	A	2: 120,189,433 (GRCm38)	T179S	probably benign	Het
Popdc2	G	A	16: 38,374,147 (GRCm38)	C310Y	probably benign	Het
Ppip5k1	C	T	2: 121,323,346 (GRCm38)	R113Q		Het
Prmt7	C	T	8: 106,235,033 (GRCm38)	R193C	unknown	Het
Prph	G	C	15: 99,057,478 (GRCm38)	R442P	probably damaging	Het
Prrc2b	A	G	2: 32,208,767 (GRCm38)	Y697C	probably damaging	Het
Ptprm	T	A	17: 66,762,148 (GRCm38)	R962S	probably damaging	Het
Raph1	A	G	1: 60,490,141 (GRCm38)	S654P	unknown	Het
Reln	A	G	5: 21,997,939 (GRCm38)	F1288L	probably damaging	Het
Rhot1	T	A	11: 80,254,742 (GRCm38)	I553N	probably benign	Het
Rnf168	T	C	16: 32,291,983 (GRCm38)		probably null	Het
Slamf6	T	A	1: 171,919,590 (GRCm38)		probably benign	Het
Srgap1	CTACCTCCTCTTAGGGACCACGCCCACCCCCTCCCAGGGACCATGCTTACCTCCTCTTAGGGACCACGCCCACCCCCTCCCAGGGACCATGCTTACCTCCTC	CTACCTCCTCTTAGGGACCACGCCCACCCCCTCCCAGGGACCATGCTTACCTCCTC	10: 121,853,553 (GRCm38)		probably benign	Het
Taf4b	C	T	18: 14,821,498 (GRCm38)	P544S	probably benign	Het
Tbc1d24	A	G	17: 24,208,403 (GRCm38)	V195A	probably benign	Het
Tomm70a	A	G	16: 57,122,036 (GRCm38)	M59V	probably benign	Het
Trip12	A	G	1: 84,749,298 (GRCm38)	S1184P	probably damaging	Het
Trrap	A	G	5: 144,791,115 (GRCm38)	S549G	probably benign	Het
Unc5d	T	A	8: 29,219,443 (GRCm38)		probably benign	Het
Ush2a	G	A	1: 188,576,292 (GRCm38)		probably null	Het
Usp45	T	C	4: 21,784,755 (GRCm38)	V147A	probably damaging	Het
Vmn2r77	T	A	7: 86,811,786 (GRCm38)	N773K	probably damaging	Het
Vps13c	A	T	9: 67,951,695 (GRCm38)	N2809I	probably damaging	Het
Yeats2	T	A	16: 20,213,328 (GRCm38)	S984R	possibly damaging	Het
Yeats2	T	A	16: 20,222,783 (GRCm38)	L1141Q	probably damaging	Het
Zfp58	T	A	13: 67,491,275 (GRCm38)	T366S	probably benign	Het

Other mutations in Pkd1l3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00336:Pkd1l3	APN	8	109,630,237 (GRCm38)	missense	possibly damaging	0.53
IGL00562:Pkd1l3	APN	8	109,656,147 (GRCm38)	missense	possibly damaging	0.53
IGL00563:Pkd1l3	APN	8	109,656,147 (GRCm38)	missense	possibly damaging	0.53
IGL01061:Pkd1l3	APN	8	109,638,706 (GRCm38)	missense	probably damaging	1.00
IGL01105:Pkd1l3	APN	8	109,662,241 (GRCm38)	missense	possibly damaging	0.81
IGL01574:Pkd1l3	APN	8	109,623,771 (GRCm38)	missense	probably benign	0.01
IGL01597:Pkd1l3	APN	8	109,623,521 (GRCm38)	missense	probably benign	0.33
IGL01634:Pkd1l3	APN	8	109,667,525 (GRCm38)	critical splice acceptor site	probably null
IGL01645:Pkd1l3	APN	8	109,635,302 (GRCm38)	missense	possibly damaging	0.59
IGL01770:Pkd1l3	APN	8	109,648,502 (GRCm38)	critical splice acceptor site	probably null
IGL01837:Pkd1l3	APN	8	109,630,166 (GRCm38)	missense	possibly damaging	0.85
IGL01862:Pkd1l3	APN	8	109,631,276 (GRCm38)	critical splice acceptor site	probably null
IGL01938:Pkd1l3	APN	8	109,635,301 (GRCm38)	missense	probably benign	0.00
IGL01990:Pkd1l3	APN	8	109,660,806 (GRCm38)	missense	probably damaging	1.00
IGL02056:Pkd1l3	APN	8	109,631,378 (GRCm38)	missense	probably benign	0.14
IGL02069:Pkd1l3	APN	8	109,635,380 (GRCm38)	missense	probably damaging	1.00
IGL02086:Pkd1l3	APN	8	109,665,585 (GRCm38)	missense	probably damaging	1.00
IGL02152:Pkd1l3	APN	8	109,669,292 (GRCm38)	missense	probably damaging	1.00
IGL02209:Pkd1l3	APN	8	109,638,664 (GRCm38)	missense	probably damaging	1.00
IGL02213:Pkd1l3	APN	8	109,631,345 (GRCm38)	missense	probably damaging	1.00
IGL02218:Pkd1l3	APN	8	109,660,802 (GRCm38)	missense	possibly damaging	0.92
IGL02225:Pkd1l3	APN	8	109,638,678 (GRCm38)	missense	probably damaging	1.00
IGL02252:Pkd1l3	APN	8	109,631,076 (GRCm38)	missense	possibly damaging	0.92
IGL02351:Pkd1l3	APN	8	109,646,497 (GRCm38)	unclassified	probably benign
IGL02358:Pkd1l3	APN	8	109,646,497 (GRCm38)	unclassified	probably benign
IGL02369:Pkd1l3	APN	8	109,616,345 (GRCm38)	missense	unknown
IGL02481:Pkd1l3	APN	8	109,614,782 (GRCm38)	missense	unknown
IGL02505:Pkd1l3	APN	8	109,633,216 (GRCm38)	missense	probably damaging	1.00
IGL02506:Pkd1l3	APN	8	109,647,500 (GRCm38)	missense	probably damaging	1.00
IGL02535:Pkd1l3	APN	8	109,640,890 (GRCm38)	nonsense	probably null
IGL02715:Pkd1l3	APN	8	109,626,826 (GRCm38)	missense	probably damaging	0.96
IGL02979:Pkd1l3	APN	8	109,662,104 (GRCm38)	splice site	probably benign
IGL03059:Pkd1l3	APN	8	109,648,367 (GRCm38)	missense	probably damaging	1.00
IGL03090:Pkd1l3	APN	8	109,655,533 (GRCm38)	nonsense	probably null
IGL03206:Pkd1l3	APN	8	109,623,713 (GRCm38)	missense	probably benign	0.18
IGL03328:Pkd1l3	APN	8	109,662,106 (GRCm38)	splice site	probably benign
BB006:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
PIT4453001:Pkd1l3	UTSW	8	109,660,801 (GRCm38)	missense	probably damaging	0.99
PIT4468001:Pkd1l3	UTSW	8	109,664,499 (GRCm38)	missense	possibly damaging	0.85
R0001:Pkd1l3	UTSW	8	109,628,633 (GRCm38)	splice site	probably benign
R0066:Pkd1l3	UTSW	8	109,620,471 (GRCm38)	missense	unknown
R0066:Pkd1l3	UTSW	8	109,620,471 (GRCm38)	missense	unknown
R0233:Pkd1l3	UTSW	8	109,650,780 (GRCm38)	nonsense	probably null
R0233:Pkd1l3	UTSW	8	109,650,780 (GRCm38)	nonsense	probably null
R0255:Pkd1l3	UTSW	8	109,638,754 (GRCm38)	missense	probably damaging	1.00
R0288:Pkd1l3	UTSW	8	109,646,499 (GRCm38)	splice site	probably null
R0311:Pkd1l3	UTSW	8	109,623,663 (GRCm38)	missense	probably benign	0.33
R0311:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0403:Pkd1l3	UTSW	8	109,623,663 (GRCm38)	missense	probably benign	0.33
R0403:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0441:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0446:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0465:Pkd1l3	UTSW	8	109,623,663 (GRCm38)	missense	probably benign	0.33
R0465:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0466:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0467:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0468:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0488:Pkd1l3	UTSW	8	109,623,663 (GRCm38)	missense	probably benign	0.33
R0488:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0515:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0534:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0650:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R0689:Pkd1l3	UTSW	8	109,623,649 (GRCm38)	missense	possibly damaging	0.70
R1422:Pkd1l3	UTSW	8	109,621,708 (GRCm38)	missense	unknown
R1464:Pkd1l3	UTSW	8	109,636,427 (GRCm38)	splice site	probably benign
R1467:Pkd1l3	UTSW	8	109,616,368 (GRCm38)	missense	unknown
R1467:Pkd1l3	UTSW	8	109,616,368 (GRCm38)	missense	unknown
R1469:Pkd1l3	UTSW	8	109,646,953 (GRCm38)	missense	possibly damaging	0.72
R1469:Pkd1l3	UTSW	8	109,646,953 (GRCm38)	missense	possibly damaging	0.72
R1509:Pkd1l3	UTSW	8	109,640,770 (GRCm38)	missense	probably damaging	0.99
R1561:Pkd1l3	UTSW	8	109,614,813 (GRCm38)	missense	unknown
R1574:Pkd1l3	UTSW	8	109,614,813 (GRCm38)	missense	unknown
R1599:Pkd1l3	UTSW	8	109,636,384 (GRCm38)	missense	probably benign	0.01
R1688:Pkd1l3	UTSW	8	109,623,818 (GRCm38)	missense	probably benign	0.18
R1792:Pkd1l3	UTSW	8	109,632,605 (GRCm38)	missense	probably damaging	1.00
R1818:Pkd1l3	UTSW	8	109,648,406 (GRCm38)	missense	probably benign	0.03
R1896:Pkd1l3	UTSW	8	109,624,199 (GRCm38)	missense	possibly damaging	0.92
R2105:Pkd1l3	UTSW	8	109,647,573 (GRCm38)	nonsense	probably null
R2185:Pkd1l3	UTSW	8	109,633,195 (GRCm38)	missense	possibly damaging	0.95
R2192:Pkd1l3	UTSW	8	109,620,524 (GRCm38)	missense	unknown
R2260:Pkd1l3	UTSW	8	109,623,636 (GRCm38)	missense	probably benign	0.18
R2363:Pkd1l3	UTSW	8	109,628,709 (GRCm38)	missense	probably benign	0.01
R2418:Pkd1l3	UTSW	8	109,670,721 (GRCm38)	makesense	probably null
R2435:Pkd1l3	UTSW	8	109,650,702 (GRCm38)	missense	probably benign	0.07
R2443:Pkd1l3	UTSW	8	109,623,815 (GRCm38)	missense	probably benign	0.18
R2850:Pkd1l3	UTSW	8	109,623,990 (GRCm38)	missense	possibly damaging	0.92
R2910:Pkd1l3	UTSW	8	109,667,636 (GRCm38)	splice site	probably benign
R3755:Pkd1l3	UTSW	8	109,632,539 (GRCm38)	missense	probably damaging	1.00
R3791:Pkd1l3	UTSW	8	109,636,317 (GRCm38)	missense	probably damaging	0.99
R3905:Pkd1l3	UTSW	8	109,646,879 (GRCm38)	missense	probably benign	0.02
R4027:Pkd1l3	UTSW	8	109,623,971 (GRCm38)	missense	possibly damaging	0.68
R4028:Pkd1l3	UTSW	8	109,623,971 (GRCm38)	missense	possibly damaging	0.68
R4029:Pkd1l3	UTSW	8	109,623,971 (GRCm38)	missense	possibly damaging	0.68
R4274:Pkd1l3	UTSW	8	109,624,119 (GRCm38)	missense	possibly damaging	0.92
R4461:Pkd1l3	UTSW	8	109,632,713 (GRCm38)	splice site	probably null
R4893:Pkd1l3	UTSW	8	109,638,394 (GRCm38)	missense	probably benign	0.15
R4907:Pkd1l3	UTSW	8	109,640,843 (GRCm38)	missense	probably damaging	0.99
R5037:Pkd1l3	UTSW	8	109,665,636 (GRCm38)	missense	probably damaging	1.00
R5045:Pkd1l3	UTSW	8	109,623,155 (GRCm38)	missense	unknown
R5207:Pkd1l3	UTSW	8	109,633,191 (GRCm38)	missense	probably damaging	1.00
R5307:Pkd1l3	UTSW	8	109,640,792 (GRCm38)	missense	probably damaging	1.00
R5408:Pkd1l3	UTSW	8	109,667,052 (GRCm38)	missense	probably damaging	1.00
R5595:Pkd1l3	UTSW	8	109,655,520 (GRCm38)	missense	probably damaging	1.00
R5615:Pkd1l3	UTSW	8	109,630,210 (GRCm38)	missense	probably benign
R5623:Pkd1l3	UTSW	8	109,623,719 (GRCm38)	missense	possibly damaging	0.53
R5896:Pkd1l3	UTSW	8	109,626,836 (GRCm38)	missense	probably damaging	1.00
R6101:Pkd1l3	UTSW	8	109,640,846 (GRCm38)	missense	probably damaging	1.00
R6105:Pkd1l3	UTSW	8	109,640,846 (GRCm38)	missense	probably damaging	1.00
R6170:Pkd1l3	UTSW	8	109,623,179 (GRCm38)	missense	unknown
R6330:Pkd1l3	UTSW	8	109,646,909 (GRCm38)	missense	probably benign	0.00
R6346:Pkd1l3	UTSW	8	109,631,384 (GRCm38)	missense	probably damaging	0.98
R6395:Pkd1l3	UTSW	8	109,623,963 (GRCm38)	missense	probably benign	0.20
R6475:Pkd1l3	UTSW	8	109,623,212 (GRCm38)	missense	unknown
R6480:Pkd1l3	UTSW	8	109,638,387 (GRCm38)	nonsense	probably null
R6519:Pkd1l3	UTSW	8	109,628,772 (GRCm38)	missense	probably benign
R6654:Pkd1l3	UTSW	8	109,624,283 (GRCm38)	missense	probably benign	0.23
R6717:Pkd1l3	UTSW	8	109,614,769 (GRCm38)	missense	unknown
R6733:Pkd1l3	UTSW	8	109,648,494 (GRCm38)	splice site	probably null
R6753:Pkd1l3	UTSW	8	109,624,449 (GRCm38)	missense	probably damaging	1.00
R6777:Pkd1l3	UTSW	8	109,626,814 (GRCm38)	missense	probably benign	0.00
R6901:Pkd1l3	UTSW	8	109,614,614 (GRCm38)	missense	unknown
R6975:Pkd1l3	UTSW	8	109,660,907 (GRCm38)	missense	possibly damaging	0.73
R6991:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7018:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7083:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7139:Pkd1l3	UTSW	8	109,636,340 (GRCm38)	missense	probably damaging	0.96
R7153:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7235:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7238:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7252:Pkd1l3	UTSW	8	109,660,698 (GRCm38)	missense	probably benign	0.01
R7296:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7309:Pkd1l3	UTSW	8	109,648,261 (GRCm38)	splice site	probably null
R7362:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7462:Pkd1l3	UTSW	8	109,628,777 (GRCm38)	missense	probably benign	0.00
R7470:Pkd1l3	UTSW	8	109,638,376 (GRCm38)	missense	probably benign	0.09
R7478:Pkd1l3	UTSW	8	109,633,315 (GRCm38)	missense	probably damaging	1.00
R7483:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7516:Pkd1l3	UTSW	8	109,635,229 (GRCm38)	missense	probably damaging	1.00
R7553:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7559:Pkd1l3	UTSW	8	109,624,440 (GRCm38)	missense	probably benign	0.03
R7650:Pkd1l3	UTSW	8	109,672,585 (GRCm38)	missense	probably benign	0.23
R7654:Pkd1l3	UTSW	8	109,638,417 (GRCm38)	missense	probably damaging	1.00
R7742:Pkd1l3	UTSW	8	109,614,572 (GRCm38)	missense	unknown
R7749:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7751:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7755:Pkd1l3	UTSW	8	109,630,166 (GRCm38)	missense	possibly damaging	0.85
R7816:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7831:Pkd1l3	UTSW	8	109,631,358 (GRCm38)	missense	possibly damaging	0.47
R7835:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7849:Pkd1l3	UTSW	8	109,623,788 (GRCm38)	small deletion	probably benign
R7917:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7929:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R7952:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8054:Pkd1l3	UTSW	8	109,646,376 (GRCm38)	missense	probably damaging	1.00
R8098:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8099:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8276:Pkd1l3	UTSW	8	109,670,721 (GRCm38)	makesense	probably null
R8352:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8376:Pkd1l3	UTSW	8	109,623,788 (GRCm38)	small deletion	probably benign
R8377:Pkd1l3	UTSW	8	109,635,350 (GRCm38)	missense	probably benign	0.08
R8398:Pkd1l3	UTSW	8	109,623,888 (GRCm38)	missense	possibly damaging	0.93
R8399:Pkd1l3	UTSW	8	109,623,888 (GRCm38)	missense	possibly damaging	0.93
R8400:Pkd1l3	UTSW	8	109,623,888 (GRCm38)	missense	possibly damaging	0.93
R8412:Pkd1l3	UTSW	8	109,633,390 (GRCm38)	missense	possibly damaging	0.85
R8530:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8539:Pkd1l3	UTSW	8	109,636,287 (GRCm38)	missense	probably damaging	1.00
R8546:Pkd1l3	UTSW	8	109,666,983 (GRCm38)	missense	possibly damaging	0.52
R8558:Pkd1l3	UTSW	8	109,635,380 (GRCm38)	missense	probably damaging	1.00
R8719:Pkd1l3	UTSW	8	109,614,623 (GRCm38)	missense	unknown
R8769:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8797:Pkd1l3	UTSW	8	109,648,314 (GRCm38)	missense	probably benign	0.15
R8840:Pkd1l3	UTSW	8	109,623,210 (GRCm38)	missense	unknown
R8846:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8874:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8893:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8956:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8963:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R8968:Pkd1l3	UTSW	8	109,623,788 (GRCm38)	small deletion	probably benign
R9035:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9054:Pkd1l3	UTSW	8	109,665,672 (GRCm38)	missense	probably benign	0.08
R9058:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9119:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9134:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9138:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9158:Pkd1l3	UTSW	8	109,667,575 (GRCm38)	nonsense	probably null
R9180:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9181:Pkd1l3	UTSW	8	109,648,686 (GRCm38)	missense	probably damaging	0.98
R9218:Pkd1l3	UTSW	8	109,655,496 (GRCm38)	nonsense	probably null
R9249:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9269:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9383:Pkd1l3	UTSW	8	109,623,969 (GRCm38)	small deletion	probably benign
R9396:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9423:Pkd1l3	UTSW	8	109,623,680 (GRCm38)	missense	possibly damaging	0.53
R9514:Pkd1l3	UTSW	8	109,669,217 (GRCm38)	missense	probably damaging	1.00
R9515:Pkd1l3	UTSW	8	109,669,217 (GRCm38)	missense	probably damaging	1.00
R9567:Pkd1l3	UTSW	8	109,667,541 (GRCm38)	missense	probably damaging	0.99
R9668:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9684:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
R9748:Pkd1l3	UTSW	8	109,646,923 (GRCm38)	missense	probably benign	0.00
R9778:Pkd1l3	UTSW	8	109,631,305 (GRCm38)	missense	probably benign	0.00
RF016:Pkd1l3	UTSW	8	109,623,542 (GRCm38)	missense	probably benign	0.18
RF029:Pkd1l3	UTSW	8	109,624,195 (GRCm38)	small deletion	probably benign
X0026:Pkd1l3	UTSW	8	109,614,553 (GRCm38)	missense	probably null
Z1176:Pkd1l3	UTSW	8	109,623,242 (GRCm38)	missense	unknown
Z31818:Pkd1l3	UTSW	8	109,669,292 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AGGTGACATCAGACACACCTG -3'
(R):5'- CCAGCAGGTATTGTGGATTCAG -3'

Sequencing Primer
(F):5'- TGACATCAGACACACCTGCATCC -3'
(R):5'- AGGCCTGGTGACCTCTGTTATAAC -3'

Posted On

2022-04-18