Incidental Mutation 'R9339:Mcm3ap'
| ID |
707389 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mcm3ap
|
| Ensembl Gene |
ENSMUSG00000001150 |
| Gene Name |
minichromosome maintenance complex component 3 associated protein |
| Synonyms |
GANP |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9339 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
76304761-76351691 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 76306358 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 157
(E157G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125960
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000049185]
[ENSMUST00000170795]
|
| AlphaFold |
Q9WUU9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000049185
|
| SMART Domains |
Protein: ENSMUSP00000045647
Gene: ENSMUSG00000033126
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:UPF0054
|
8 |
148 |
7.6e-29 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170795
AA Change: E157G
PolyPhen 2
Score 0.044 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000125960
Gene: ENSMUSG00000001150
AA Change: E157G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NupH_GANP
|
2 |
286 |
3.3e-108 |
PFAM |
|
low complexity region
|
389 |
403 |
N/A |
INTRINSIC |
|
Blast:RRM
|
430 |
504 |
5e-39 |
BLAST |
|
SCOP:d1fjeb2
|
434 |
500 |
6e-4 |
SMART |
|
low complexity region
|
544 |
559 |
N/A |
INTRINSIC |
|
low complexity region
|
570 |
586 |
N/A |
INTRINSIC |
|
Pfam:SAC3_GANP
|
677 |
903 |
1.7e-82 |
PFAM |
|
low complexity region
|
997 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1024 |
1035 |
N/A |
INTRINSIC |
|
low complexity region
|
1039 |
1053 |
N/A |
INTRINSIC |
|
low complexity region
|
1091 |
1110 |
N/A |
INTRINSIC |
|
low complexity region
|
1133 |
1155 |
N/A |
INTRINSIC |
|
Pfam:CID_GANP
|
1156 |
1226 |
1.6e-33 |
PFAM |
|
Pfam:MCM3AP_GANP
|
1254 |
1967 |
N/A |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
99% (77/78) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. [provided by RefSeq, Jan 2014]
PHENOTYPE: Mice homozygous for a null allele die by E12. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930562C15Rik |
A |
G |
16: 4,667,521 (GRCm39) |
E304G |
unknown |
Het |
| 4933436I01Rik |
T |
A |
X: 66,964,689 (GRCm39) |
K57* |
probably null |
Het |
| Aar2 |
T |
C |
2: 156,392,893 (GRCm39) |
V94A |
probably benign |
Het |
| Abcb9 |
T |
C |
5: 124,228,176 (GRCm39) |
T22A |
possibly damaging |
Het |
| Adam25 |
T |
C |
8: 41,206,911 (GRCm39) |
V59A |
probably damaging |
Het |
| Ampd2 |
T |
C |
3: 107,987,616 (GRCm39) |
D103G |
probably damaging |
Het |
| Ankrd12 |
A |
G |
17: 66,291,408 (GRCm39) |
S1342P |
probably benign |
Het |
| Atp13a2 |
A |
G |
4: 140,730,571 (GRCm39) |
T739A |
probably benign |
Het |
| Catsperg1 |
T |
A |
7: 28,894,885 (GRCm39) |
N571Y |
probably benign |
Het |
| Cela3b |
A |
G |
4: 137,152,355 (GRCm39) |
I74T |
probably damaging |
Het |
| Cfhr1 |
A |
G |
1: 139,485,293 (GRCm39) |
L51P |
probably benign |
Het |
| Cfhr4 |
T |
A |
1: 139,682,044 (GRCm39) |
Y184F |
probably benign |
Het |
| Ckap5 |
T |
A |
2: 91,396,100 (GRCm39) |
D534E |
probably benign |
Het |
| Cstf3 |
C |
T |
2: 104,493,778 (GRCm39) |
P594L |
probably damaging |
Het |
| Ctdp1 |
A |
G |
18: 80,492,689 (GRCm39) |
L602P |
probably damaging |
Het |
| Defa24 |
A |
G |
8: 22,224,559 (GRCm39) |
T3A |
probably damaging |
Het |
| Dmgdh |
A |
G |
13: 93,847,941 (GRCm39) |
H546R |
probably benign |
Het |
| Dscam |
A |
G |
16: 96,517,263 (GRCm39) |
V882A |
possibly damaging |
Het |
| Dydc2 |
A |
G |
14: 40,771,260 (GRCm39) |
*140Q |
probably null |
Het |
| Ehd4 |
T |
C |
2: 119,921,708 (GRCm39) |
D516G |
possibly damaging |
Het |
| En1 |
T |
C |
1: 120,534,893 (GRCm39) |
V394A |
unknown |
Het |
| Erich3 |
T |
G |
3: 154,468,872 (GRCm39) |
L1108R |
unknown |
Het |
| Erp27 |
A |
G |
6: 136,896,945 (GRCm39) |
S86P |
probably benign |
Het |
| Esr1 |
A |
C |
10: 4,696,798 (GRCm39) |
S216R |
probably damaging |
Het |
| Fbxo40 |
A |
T |
16: 36,789,286 (GRCm39) |
I608N |
probably damaging |
Het |
| Fcna |
G |
A |
2: 25,517,782 (GRCm39) |
Q23* |
probably null |
Het |
| Foxn4 |
C |
T |
5: 114,394,955 (GRCm39) |
R324Q |
probably benign |
Het |
| Gata6 |
A |
G |
18: 11,054,520 (GRCm39) |
T150A |
probably damaging |
Het |
| Gbp2b |
T |
A |
3: 142,317,178 (GRCm39) |
H511Q |
probably benign |
Het |
| Gpr171 |
C |
A |
3: 59,005,362 (GRCm39) |
V138L |
probably damaging |
Het |
| Grhl2 |
G |
A |
15: 37,344,904 (GRCm39) |
V509I |
probably benign |
Het |
| Gzmd |
G |
A |
14: 56,367,869 (GRCm39) |
P135S |
probably damaging |
Het |
| Hhatl |
C |
A |
9: 121,618,862 (GRCm39) |
C90F |
probably benign |
Het |
| Hspg2 |
A |
G |
4: 137,278,480 (GRCm39) |
K3050R |
probably benign |
Het |
| Kcnh3 |
T |
C |
15: 99,130,786 (GRCm39) |
Y468H |
probably damaging |
Het |
| Lhfpl6 |
A |
G |
3: 52,950,891 (GRCm39) |
H55R |
probably benign |
Het |
| Lpgat1 |
T |
C |
1: 191,451,488 (GRCm39) |
V38A |
probably benign |
Het |
| Lrrc49 |
A |
G |
9: 60,510,031 (GRCm39) |
I479T |
probably benign |
Het |
| Map1b |
A |
T |
13: 99,567,570 (GRCm39) |
I1717N |
unknown |
Het |
| Map3k20 |
G |
T |
2: 72,272,216 (GRCm39) |
R781S |
possibly damaging |
Het |
| Mylk2 |
A |
G |
2: 152,755,370 (GRCm39) |
E178G |
probably damaging |
Het |
| Naaladl2 |
A |
G |
3: 24,057,146 (GRCm39) |
L605P |
probably damaging |
Het |
| Nox4 |
G |
A |
7: 87,025,448 (GRCm39) |
R525Q |
probably benign |
Het |
| Nt5el |
C |
T |
13: 105,246,114 (GRCm39) |
T225I |
probably benign |
Het |
| Or10h28 |
T |
C |
17: 33,488,631 (GRCm39) |
V311A |
probably benign |
Het |
| Or4a76 |
T |
C |
2: 89,460,555 (GRCm39) |
E229G |
probably damaging |
Het |
| Padi3 |
A |
T |
4: 140,522,928 (GRCm39) |
I348N |
probably benign |
Het |
| Pcdh18 |
T |
C |
3: 49,709,335 (GRCm39) |
D660G |
probably damaging |
Het |
| Pdgfra |
T |
A |
5: 75,355,635 (GRCm39) |
S1048R |
probably damaging |
Het |
| Pkhd1l1 |
T |
C |
15: 44,452,949 (GRCm39) |
V3958A |
probably damaging |
Het |
| Ppargc1b |
C |
A |
18: 61,456,267 (GRCm39) |
C80F |
probably damaging |
Het |
| Rbm28 |
T |
C |
6: 29,128,674 (GRCm39) |
E590G |
probably benign |
Het |
| Rbm47 |
T |
C |
5: 66,183,826 (GRCm39) |
E259G |
possibly damaging |
Het |
| Rint1 |
A |
G |
5: 23,993,355 (GRCm39) |
*37W |
probably null |
Het |
| Sacs |
G |
A |
14: 61,443,309 (GRCm39) |
R1785Q |
probably benign |
Het |
| Samm50 |
T |
C |
15: 84,095,276 (GRCm39) |
C421R |
probably benign |
Het |
| Scnn1b |
G |
T |
7: 121,511,254 (GRCm39) |
A314S |
probably damaging |
Het |
| Sf3b3 |
C |
A |
8: 111,542,854 (GRCm39) |
V868L |
probably benign |
Het |
| Sirt5 |
G |
T |
13: 43,530,327 (GRCm39) |
V136L |
probably benign |
Het |
| Slc1a7 |
T |
C |
4: 107,850,237 (GRCm39) |
V116A |
probably damaging |
Het |
| Slc24a4 |
G |
A |
12: 102,230,638 (GRCm39) |
V510M |
probably damaging |
Het |
| Slc35f5 |
T |
C |
1: 125,517,628 (GRCm39) |
I116T |
probably benign |
Het |
| Spata4 |
T |
C |
8: 55,053,899 (GRCm39) |
S22P |
probably benign |
Het |
| Sqstm1 |
A |
G |
11: 50,091,725 (GRCm39) |
V324A |
probably benign |
Het |
| Stmnd1 |
G |
A |
13: 46,453,079 (GRCm39) |
A252T |
probably benign |
Het |
| Tbl1xr1 |
C |
A |
3: 22,258,150 (GRCm39) |
N470K |
possibly damaging |
Het |
| Thap12 |
T |
C |
7: 98,364,323 (GRCm39) |
S164P |
possibly damaging |
Het |
| Thsd1 |
A |
G |
8: 22,733,898 (GRCm39) |
Y315C |
probably damaging |
Het |
| Tnni2 |
C |
A |
7: 141,997,672 (GRCm39) |
D102E |
probably damaging |
Het |
| Trav7n-4 |
A |
C |
14: 53,328,849 (GRCm39) |
N16T |
probably benign |
Het |
| Trpm7 |
T |
C |
2: 126,665,906 (GRCm39) |
K900R |
probably benign |
Het |
| Tspoap1 |
T |
A |
11: 87,668,839 (GRCm39) |
C1371S |
probably benign |
Het |
| Tssk5 |
A |
G |
15: 76,257,156 (GRCm39) |
M242T |
possibly damaging |
Het |
| Ubn2 |
A |
G |
6: 38,460,079 (GRCm39) |
I607V |
probably benign |
Het |
| Ubr2 |
A |
T |
17: 47,284,865 (GRCm39) |
V551E |
probably benign |
Het |
| Vipr2 |
A |
G |
12: 116,058,344 (GRCm39) |
N87S |
probably damaging |
Het |
| Vmn2r18 |
T |
A |
5: 151,485,132 (GRCm39) |
K787N |
probably damaging |
Het |
| Wwc2 |
A |
T |
8: 48,353,859 (GRCm39) |
W92R |
probably damaging |
Het |
| Zfp141 |
A |
G |
7: 42,125,639 (GRCm39) |
Y278H |
probably damaging |
Het |
| Zfp827 |
T |
C |
8: 79,844,887 (GRCm39) |
S686P |
probably benign |
Het |
|
| Other mutations in Mcm3ap |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00493:Mcm3ap
|
APN |
10 |
76,307,011 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00742:Mcm3ap
|
APN |
10 |
76,328,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00898:Mcm3ap
|
APN |
10 |
76,306,159 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00984:Mcm3ap
|
APN |
10 |
76,335,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01591:Mcm3ap
|
APN |
10 |
76,306,639 (GRCm39) |
missense |
probably benign |
|
|
IGL01882:Mcm3ap
|
APN |
10 |
76,319,018 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL01973:Mcm3ap
|
APN |
10 |
76,306,951 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02253:Mcm3ap
|
APN |
10 |
76,305,899 (GRCm39) |
missense |
probably benign |
0.40 |
|
IGL02304:Mcm3ap
|
APN |
10 |
76,320,572 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL02340:Mcm3ap
|
APN |
10 |
76,332,386 (GRCm39) |
nonsense |
probably null |
|
|
IGL02487:Mcm3ap
|
APN |
10 |
76,343,389 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02488:Mcm3ap
|
APN |
10 |
76,335,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02640:Mcm3ap
|
APN |
10 |
76,342,255 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02714:Mcm3ap
|
APN |
10 |
76,346,867 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02748:Mcm3ap
|
APN |
10 |
76,337,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02894:Mcm3ap
|
APN |
10 |
76,313,601 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02903:Mcm3ap
|
APN |
10 |
76,307,092 (GRCm39) |
splice site |
probably benign |
|
|
IGL02955:Mcm3ap
|
APN |
10 |
76,343,300 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL02989:Mcm3ap
|
APN |
10 |
76,306,894 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL03003:Mcm3ap
|
APN |
10 |
76,340,531 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03081:Mcm3ap
|
APN |
10 |
76,306,150 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03218:Mcm3ap
|
APN |
10 |
76,318,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03401:Mcm3ap
|
APN |
10 |
76,320,483 (GRCm39) |
splice site |
probably benign |
|
|
Bane
|
UTSW |
10 |
76,319,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Doom
|
UTSW |
10 |
76,337,148 (GRCm39) |
missense |
probably benign |
|
|
woeful
|
UTSW |
10 |
76,316,849 (GRCm39) |
missense |
probably benign |
0.44 |
|
PIT4377001:Mcm3ap
|
UTSW |
10 |
76,338,596 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
PIT4791001:Mcm3ap
|
UTSW |
10 |
76,342,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0105:Mcm3ap
|
UTSW |
10 |
76,335,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0144:Mcm3ap
|
UTSW |
10 |
76,316,849 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0423:Mcm3ap
|
UTSW |
10 |
76,338,539 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0692:Mcm3ap
|
UTSW |
10 |
76,319,003 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1402:Mcm3ap
|
UTSW |
10 |
76,313,748 (GRCm39) |
unclassified |
probably benign |
|
|
R1441:Mcm3ap
|
UTSW |
10 |
76,307,000 (GRCm39) |
missense |
probably benign |
|
|
R1512:Mcm3ap
|
UTSW |
10 |
76,306,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1533:Mcm3ap
|
UTSW |
10 |
76,340,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1569:Mcm3ap
|
UTSW |
10 |
76,319,022 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1590:Mcm3ap
|
UTSW |
10 |
76,332,375 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1597:Mcm3ap
|
UTSW |
10 |
76,319,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1743:Mcm3ap
|
UTSW |
10 |
76,320,508 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1773:Mcm3ap
|
UTSW |
10 |
76,306,994 (GRCm39) |
missense |
probably benign |
|
|
R1922:Mcm3ap
|
UTSW |
10 |
76,343,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2061:Mcm3ap
|
UTSW |
10 |
76,305,902 (GRCm39) |
missense |
probably benign |
0.43 |
|
R2097:Mcm3ap
|
UTSW |
10 |
76,348,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2436:Mcm3ap
|
UTSW |
10 |
76,325,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3684:Mcm3ap
|
UTSW |
10 |
76,325,260 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R3690:Mcm3ap
|
UTSW |
10 |
76,318,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3881:Mcm3ap
|
UTSW |
10 |
76,342,280 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4296:Mcm3ap
|
UTSW |
10 |
76,343,171 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4677:Mcm3ap
|
UTSW |
10 |
76,306,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4786:Mcm3ap
|
UTSW |
10 |
76,324,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4882:Mcm3ap
|
UTSW |
10 |
76,320,495 (GRCm39) |
nonsense |
probably null |
|
|
R4907:Mcm3ap
|
UTSW |
10 |
76,329,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5108:Mcm3ap
|
UTSW |
10 |
76,338,536 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5279:Mcm3ap
|
UTSW |
10 |
76,343,373 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5316:Mcm3ap
|
UTSW |
10 |
76,306,760 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5402:Mcm3ap
|
UTSW |
10 |
76,319,148 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5459:Mcm3ap
|
UTSW |
10 |
76,332,316 (GRCm39) |
nonsense |
probably null |
|
|
R5473:Mcm3ap
|
UTSW |
10 |
76,338,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5570:Mcm3ap
|
UTSW |
10 |
76,316,930 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5931:Mcm3ap
|
UTSW |
10 |
76,307,000 (GRCm39) |
missense |
probably benign |
|
|
R5939:Mcm3ap
|
UTSW |
10 |
76,344,195 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5950:Mcm3ap
|
UTSW |
10 |
76,324,253 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5998:Mcm3ap
|
UTSW |
10 |
76,316,976 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6122:Mcm3ap
|
UTSW |
10 |
76,342,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6192:Mcm3ap
|
UTSW |
10 |
76,336,934 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6226:Mcm3ap
|
UTSW |
10 |
76,351,540 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6293:Mcm3ap
|
UTSW |
10 |
76,307,312 (GRCm39) |
nonsense |
probably null |
|
|
R6669:Mcm3ap
|
UTSW |
10 |
76,343,171 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6715:Mcm3ap
|
UTSW |
10 |
76,325,366 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6759:Mcm3ap
|
UTSW |
10 |
76,337,148 (GRCm39) |
missense |
probably benign |
|
|
R6864:Mcm3ap
|
UTSW |
10 |
76,343,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6870:Mcm3ap
|
UTSW |
10 |
76,306,049 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6935:Mcm3ap
|
UTSW |
10 |
76,340,087 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6947:Mcm3ap
|
UTSW |
10 |
76,351,500 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7212:Mcm3ap
|
UTSW |
10 |
76,337,145 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7403:Mcm3ap
|
UTSW |
10 |
76,318,657 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7470:Mcm3ap
|
UTSW |
10 |
76,344,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7561:Mcm3ap
|
UTSW |
10 |
76,328,712 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7610:Mcm3ap
|
UTSW |
10 |
76,332,554 (GRCm39) |
splice site |
probably null |
|
|
R7620:Mcm3ap
|
UTSW |
10 |
76,306,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7898:Mcm3ap
|
UTSW |
10 |
76,342,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8266:Mcm3ap
|
UTSW |
10 |
76,312,414 (GRCm39) |
nonsense |
probably null |
|
|
R8355:Mcm3ap
|
UTSW |
10 |
76,329,335 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8367:Mcm3ap
|
UTSW |
10 |
76,313,693 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8867:Mcm3ap
|
UTSW |
10 |
76,306,538 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9282:Mcm3ap
|
UTSW |
10 |
76,342,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9319:Mcm3ap
|
UTSW |
10 |
76,318,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9554:Mcm3ap
|
UTSW |
10 |
76,332,310 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9706:Mcm3ap
|
UTSW |
10 |
76,312,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Mcm3ap
|
UTSW |
10 |
76,318,619 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCGCAGCTACTTCGAGTTCC -3'
(R):5'- CTGACGTAGAAACCCTCTTCTC -3'
Sequencing Primer
(F):5'- CTCTGTGCCCGGCAATAC -3'
(R):5'- CTACATTTTGGTTAGACAAAGGAGAG -3'
|
| Posted On |
2022-04-18 |
Incidental Mutation