Mutagenetix > Incidental Mutation

Incidental Mutation 'R9340:Ahnak'

707475

Institutional Source

Beutler Lab

Gene Symbol

Ahnak

Ensembl Gene

ENSMUSG00000069833

Gene Name

AHNAK nucleoprotein

Synonyms

DY6, 1110004P15Rik, 2310047C17Rik

MMRRC Submission

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.313) question?

Stock #

R9340 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

8966648-9054278 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 8994411 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Leucine at position 5232 (M5232L)

Ref Sequence

ENSEMBL: ENSMUSP00000090633 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092955] [ENSMUST00000092956]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000092955

SMART Domains

Protein: ENSMUSP00000090632
Gene: ENSMUSG00000069833

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000092956
AA Change: M5232L

PolyPhen 2 Score 0.038 (Sensitivity: 0.94; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000090633
Gene: ENSMUSG00000069833
AA Change: M5232L

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART
internal_repeat_2	163	1515	5.22e-182	PROSPERO
internal_repeat_1	224	2314	N/A	PROSPERO
internal_repeat_2	1532	3028	5.22e-182	PROSPERO
internal_repeat_1	2660	5095	N/A	PROSPERO
low complexity region	5336	5353	N/A	INTRINSIC
low complexity region	5493	5504	N/A	INTRINSIC
low complexity region	5580	5600	N/A	INTRINSIC
low complexity region	5620	5636	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.4%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for one knock-out allele exhibit decreased T cell proliferation and increased susceptibility to parasitic infection. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 57 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930486L24Rik	T	A	13: 61,001,647 (GRCm39)	M58L	probably benign	Het
Abca8b	A	G	11: 109,840,939 (GRCm39)	V1078A	probably benign	Het
Acvr2b	A	G	9: 119,257,492 (GRCm39)	D175G	probably damaging	Het
Adad2	A	G	8: 120,339,769 (GRCm39)	M84V	probably benign	Het
Ahsa1	T	C	12: 87,315,053 (GRCm39)	S69P	probably damaging	Het
Aipl1	C	T	11: 71,928,253 (GRCm39)	G11D	probably damaging	Het
Antxr2	G	T	5: 98,086,306 (GRCm39)	P434T	probably damaging	Het
Arap1	T	C	7: 101,037,382 (GRCm39)	Y470H	probably damaging	Het
Baz1a	A	G	12: 54,963,372 (GRCm39)	I907T	probably damaging	Het
Baz1b	A	T	5: 135,246,729 (GRCm39)	Q726L	probably benign	Het
Bcar3	C	T	3: 122,298,462 (GRCm39)		probably benign	Het
Bean1	C	T	8: 104,908,739 (GRCm39)	R39C	probably damaging	Het
Cass4	A	T	2: 172,268,686 (GRCm39)	N256I	possibly damaging	Het
Cnot10	T	C	9: 114,460,897 (GRCm39)	K91R	probably benign	Het
Col6a6	C	T	9: 105,651,757 (GRCm39)	V1085M	probably damaging	Het
Dpf3	A	G	12: 83,534,449 (GRCm39)		probably null	Het
Dync1i2	T	A	2: 71,093,019 (GRCm39)	W605R	probably damaging	Het
Exoc5	A	T	14: 49,286,297 (GRCm39)	V110E	probably damaging	Het
Fgfr2	T	A	7: 129,782,136 (GRCm39)	H563L	probably damaging	Het
Fosl2	A	G	5: 32,304,379 (GRCm39)	T105A	probably benign	Het
Fsip2	A	G	2: 82,818,604 (GRCm39)	H4779R	possibly damaging	Het
Fuca2	A	G	10: 13,382,518 (GRCm39)	Y268C	probably damaging	Het
Galnt13	G	A	2: 54,770,161 (GRCm39)	E318K	probably damaging	Het
Hc	G	A	2: 34,876,294 (GRCm39)	T1584I	probably damaging	Het
Helb	T	C	10: 119,928,556 (GRCm39)	K762E	probably damaging	Het
Hspg2	T	G	4: 137,296,827 (GRCm39)	L4335R	probably damaging	Het
Ift88	A	C	14: 57,718,920 (GRCm39)	Q635P	probably damaging	Het
Inpp5a	C	A	7: 138,969,380 (GRCm39)	D25E	probably benign	Het
Kcnu1	A	G	8: 26,376,786 (GRCm39)	T387A	possibly damaging	Het
Lamb1	G	A	12: 31,374,223 (GRCm39)	D1529N	probably benign	Het
Lamb1	A	T	12: 31,374,224 (GRCm39)	D1529V	probably benign	Het
Lnx1	T	C	5: 74,758,584 (GRCm39)	N476S	probably benign	Het
Mup17	T	C	4: 61,512,633 (GRCm39)	M87V	probably benign	Het
Naip6	G	A	13: 100,452,494 (GRCm39)	T189I	probably damaging	Het
Nf1	T	A	11: 79,447,629 (GRCm39)	Y462N	possibly damaging	Het
Nup133	T	C	8: 124,664,881 (GRCm39)	D270G	probably benign	Het
Obox2	T	C	7: 15,130,789 (GRCm39)	L7S	probably damaging	Het
Obox6	A	T	7: 15,567,722 (GRCm39)	S242T	possibly damaging	Het
Ogfr	AGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCAAAAGGCCAGGTGGAGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAAGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGGGGCCAGAG	AGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCAAAAGGCCAGGTGGAGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAAGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGGGGCCAGAG	2: 180,236,850 (GRCm39)		probably benign	Het
Pigyl	C	T	9: 22,069,130 (GRCm39)		probably benign	Het
Rasa1	A	G	13: 85,369,649 (GRCm39)	V891A	probably damaging	Het
Rxrg	A	G	1: 167,458,890 (GRCm39)	D292G	possibly damaging	Het
Saal1	A	G	7: 46,351,248 (GRCm39)	F243L	probably benign	Het
Sec24c	G	A	14: 20,729,598 (GRCm39)	V59M	probably benign	Het
Sema4f	C	A	6: 82,890,890 (GRCm39)	G639V	probably damaging	Het
Serpinb1c	A	T	13: 33,066,172 (GRCm39)	C258S	probably benign	Het
Snx21	CACCTGCAGGCAGTGCCAGAGCTACGCCAAGCTCCGGACCTGCAGG	CACCTGCAGG	2: 164,633,849 (GRCm39)		probably benign	Het
Syndig1	T	C	2: 149,845,175 (GRCm39)	S233P	probably damaging	Het
Taf6l	A	T	19: 8,752,636 (GRCm39)	L377M	probably damaging	Het
Tcl1	T	C	12: 105,184,979 (GRCm39)	Y77C	probably damaging	Het
Tekt2	C	A	4: 126,216,952 (GRCm39)	M272I	probably benign	Het
Trp53bp1	T	C	2: 121,100,460 (GRCm39)	E98G	probably benign	Het
Ubr4	T	A	4: 139,182,763 (GRCm39)	I383N	unknown	Het
Wdr89	G	T	12: 75,679,937 (GRCm39)	P106T	probably benign	Het
Zfp534	T	C	4: 147,758,698 (GRCm39)	E657G	possibly damaging	Het
Zfp69	T	C	4: 120,788,013 (GRCm39)	K434R	probably damaging	Het
Zfyve26	T	A	12: 79,321,680 (GRCm39)	K980*	probably null	Het

Other mutations in Ahnak

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00467:Ahnak	APN	19	8,984,587 (GRCm39)	missense	probably damaging	0.99
IGL00509:Ahnak	APN	19	8,987,315 (GRCm39)	missense	possibly damaging	0.94
IGL00539:Ahnak	APN	19	8,985,272 (GRCm39)	missense	possibly damaging	0.50
IGL00558:Ahnak	APN	19	8,981,671 (GRCm39)	missense	possibly damaging	0.93
IGL00567:Ahnak	APN	19	8,990,747 (GRCm39)	missense	probably benign	0.24
IGL00706:Ahnak	APN	19	8,991,094 (GRCm39)	nonsense	probably null
IGL00807:Ahnak	APN	19	8,985,886 (GRCm39)	missense	possibly damaging	0.92
IGL00870:Ahnak	APN	19	8,991,062 (GRCm39)	missense	probably damaging	1.00
IGL01101:Ahnak	APN	19	8,990,251 (GRCm39)	intron	probably benign
IGL01118:Ahnak	APN	19	8,989,942 (GRCm39)	missense	probably damaging	1.00
IGL01288:Ahnak	APN	19	8,979,858 (GRCm39)	missense	possibly damaging	0.94
IGL01324:Ahnak	APN	19	8,980,396 (GRCm39)	missense	probably damaging	1.00
IGL01341:Ahnak	APN	19	8,989,067 (GRCm39)	missense	probably benign
IGL01541:Ahnak	APN	19	8,985,243 (GRCm39)	missense	possibly damaging	0.95
IGL01580:Ahnak	APN	19	8,980,203 (GRCm39)	missense	probably benign	0.02
IGL01595:Ahnak	APN	19	8,980,865 (GRCm39)	nonsense	probably null
IGL01746:Ahnak	APN	19	8,982,276 (GRCm39)	missense	possibly damaging	0.89
IGL01766:Ahnak	APN	19	8,977,482 (GRCm39)	missense	unknown
IGL01821:Ahnak	APN	19	8,989,482 (GRCm39)	missense	probably benign
IGL01913:Ahnak	APN	19	8,983,428 (GRCm39)	nonsense	probably null
IGL01934:Ahnak	APN	19	8,980,021 (GRCm39)	missense	probably damaging	1.00
IGL01940:Ahnak	APN	19	8,983,921 (GRCm39)	missense	probably benign	0.14
IGL01958:Ahnak	APN	19	8,992,273 (GRCm39)	missense	possibly damaging	0.59
IGL02145:Ahnak	APN	19	8,980,219 (GRCm39)	missense	probably benign	0.11
IGL02246:Ahnak	APN	19	8,985,632 (GRCm39)	missense	probably damaging	1.00
IGL02282:Ahnak	APN	19	8,983,351 (GRCm39)	missense	probably damaging	1.00
IGL02428:Ahnak	APN	19	8,992,197 (GRCm39)	missense	possibly damaging	0.83
IGL02442:Ahnak	APN	19	8,981,380 (GRCm39)	missense	probably damaging	1.00
IGL02474:Ahnak	APN	19	8,982,297 (GRCm39)	missense	probably benign	0.13
IGL02483:Ahnak	APN	19	8,980,672 (GRCm39)	missense	probably benign	0.01
IGL02616:Ahnak	APN	19	8,982,991 (GRCm39)	missense	probably benign	0.03
IGL02630:Ahnak	APN	19	8,989,441 (GRCm39)	missense	probably damaging	1.00
IGL02690:Ahnak	APN	19	8,989,948 (GRCm39)	nonsense	probably null
IGL02717:Ahnak	APN	19	8,979,751 (GRCm39)	missense	probably benign	0.00
IGL02721:Ahnak	APN	19	8,987,071 (GRCm39)	missense	probably benign	0.07
IGL02737:Ahnak	APN	19	8,981,957 (GRCm39)	missense	probably benign	0.17
IGL02850:Ahnak	APN	19	8,979,960 (GRCm39)	missense	probably benign	0.00
IGL03071:Ahnak	APN	19	8,989,282 (GRCm39)	missense	possibly damaging	0.63
IGL03072:Ahnak	APN	19	8,983,872 (GRCm39)	missense	probably benign	0.11
IGL03094:Ahnak	APN	19	8,980,911 (GRCm39)	missense	possibly damaging	0.64
IGL03140:Ahnak	APN	19	8,982,576 (GRCm39)	intron	probably benign
IGL03176:Ahnak	APN	19	8,979,813 (GRCm39)	missense	probably damaging	1.00
IGL03176:Ahnak	APN	19	8,985,530 (GRCm39)	missense	possibly damaging	0.56
IGL03189:Ahnak	APN	19	8,988,603 (GRCm39)	missense	possibly damaging	0.65
IGL03357:Ahnak	APN	19	8,986,689 (GRCm39)	intron	probably benign
IGL03371:Ahnak	APN	19	8,981,592 (GRCm39)	missense	possibly damaging	0.91
Eskimo	UTSW	19	8,986,938 (GRCm39)	missense	probably benign	0.31
Nanook	UTSW	19	8,980,595 (GRCm39)	missense	probably benign	0.42
Netsilik	UTSW	19	8,979,685 (GRCm39)	missense	probably benign	0.00
IGL03097:Ahnak	UTSW	19	8,979,751 (GRCm39)	missense	probably benign	0.00
PIT4403001:Ahnak	UTSW	19	8,983,540 (GRCm39)	missense	possibly damaging	0.87
R0054:Ahnak	UTSW	19	8,989,420 (GRCm39)	missense	probably damaging	1.00
R0094:Ahnak	UTSW	19	8,991,257 (GRCm39)	missense	probably benign	0.12
R0110:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0141:Ahnak	UTSW	19	8,984,044 (GRCm39)	missense	probably damaging	1.00
R0166:Ahnak	UTSW	19	8,983,089 (GRCm39)	missense	probably damaging	1.00
R0309:Ahnak	UTSW	19	8,979,859 (GRCm39)	missense	probably damaging	1.00
R0368:Ahnak	UTSW	19	8,985,714 (GRCm39)	nonsense	probably null
R0386:Ahnak	UTSW	19	8,988,508 (GRCm39)	missense	possibly damaging	0.94
R0401:Ahnak	UTSW	19	8,992,480 (GRCm39)	missense	probably benign	0.24
R0415:Ahnak	UTSW	19	8,990,235 (GRCm39)	intron	probably benign
R0463:Ahnak	UTSW	19	8,986,771 (GRCm39)	intron	probably benign
R0469:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0470:Ahnak	UTSW	19	8,986,331 (GRCm39)	missense	probably benign	0.29
R0487:Ahnak	UTSW	19	8,991,484 (GRCm39)	missense	probably damaging	0.99
R0487:Ahnak	UTSW	19	8,984,515 (GRCm39)	missense	probably benign	0.00
R0499:Ahnak	UTSW	19	8,977,628 (GRCm39)	splice site	probably benign
R0506:Ahnak	UTSW	19	8,986,492 (GRCm39)	missense	probably damaging	1.00
R0510:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0557:Ahnak	UTSW	19	8,979,308 (GRCm39)	missense	probably benign	0.10
R0570:Ahnak	UTSW	19	8,991,062 (GRCm39)	missense	probably damaging	1.00
R0610:Ahnak	UTSW	19	8,985,242 (GRCm39)	missense	probably benign	0.08
R0646:Ahnak	UTSW	19	8,990,766 (GRCm39)	nonsense	probably null
R0659:Ahnak	UTSW	19	8,992,366 (GRCm39)	missense	possibly damaging	0.60
R0791:Ahnak	UTSW	19	8,994,098 (GRCm39)	missense	probably benign	0.01
R0792:Ahnak	UTSW	19	8,994,098 (GRCm39)	missense	probably benign	0.01
R0840:Ahnak	UTSW	19	8,982,427 (GRCm39)	missense	probably damaging	1.00
R0847:Ahnak	UTSW	19	8,983,797 (GRCm39)	nonsense	probably null
R0941:Ahnak	UTSW	19	8,987,278 (GRCm39)	missense	probably damaging	1.00
R0962:Ahnak	UTSW	19	8,990,212 (GRCm39)	intron	probably benign
R1017:Ahnak	UTSW	19	8,987,907 (GRCm39)	missense	probably damaging	0.99
R1037:Ahnak	UTSW	19	8,984,982 (GRCm39)	missense	probably benign	0.27
R1085:Ahnak	UTSW	19	8,990,489 (GRCm39)	missense	possibly damaging	0.50
R1113:Ahnak	UTSW	19	8,982,984 (GRCm39)	missense	probably benign	0.29
R1140:Ahnak	UTSW	19	8,981,609 (GRCm39)	missense	probably damaging	1.00
R1158:Ahnak	UTSW	19	8,991,290 (GRCm39)	missense	probably benign	0.00
R1218:Ahnak	UTSW	19	8,992,983 (GRCm39)	missense	probably damaging	1.00
R1225:Ahnak	UTSW	19	8,980,247 (GRCm39)	missense	probably damaging	1.00
R1245:Ahnak	UTSW	19	8,981,533 (GRCm39)	missense	probably benign	0.44
R1421:Ahnak	UTSW	19	8,992,995 (GRCm39)	missense	possibly damaging	0.95
R1447:Ahnak	UTSW	19	8,984,446 (GRCm39)	missense	probably damaging	0.98
R1464:Ahnak	UTSW	19	8,982,260 (GRCm39)	missense	probably damaging	1.00
R1464:Ahnak	UTSW	19	8,982,260 (GRCm39)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	8,993,239 (GRCm39)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	8,993,239 (GRCm39)	missense	probably damaging	1.00
R1471:Ahnak	UTSW	19	8,990,296 (GRCm39)	intron	probably benign
R1507:Ahnak	UTSW	19	8,987,441 (GRCm39)	missense	probably damaging	1.00
R1521:Ahnak	UTSW	19	8,982,092 (GRCm39)	missense	probably benign	0.11
R1568:Ahnak	UTSW	19	8,979,739 (GRCm39)	missense	probably damaging	0.98
R1569:Ahnak	UTSW	19	8,981,458 (GRCm39)	missense	possibly damaging	0.78
R1616:Ahnak	UTSW	19	8,986,351 (GRCm39)	missense	possibly damaging	0.94
R1638:Ahnak	UTSW	19	8,986,813 (GRCm39)	missense	probably benign	0.01
R1680:Ahnak	UTSW	19	8,987,327 (GRCm39)	missense	probably benign	0.05
R1713:Ahnak	UTSW	19	8,989,173 (GRCm39)	missense	possibly damaging	0.95
R1722:Ahnak	UTSW	19	8,988,019 (GRCm39)	missense	probably damaging	0.99
R1771:Ahnak	UTSW	19	8,991,117 (GRCm39)	missense	probably benign	0.24
R1795:Ahnak	UTSW	19	8,979,802 (GRCm39)	missense	possibly damaging	0.79
R1823:Ahnak	UTSW	19	8,982,269 (GRCm39)	missense	probably damaging	0.99
R1842:Ahnak	UTSW	19	8,983,231 (GRCm39)	missense	probably damaging	0.99
R1854:Ahnak	UTSW	19	8,991,196 (GRCm39)	missense	possibly damaging	0.61
R1856:Ahnak	UTSW	19	8,979,412 (GRCm39)	missense	possibly damaging	0.86
R1886:Ahnak	UTSW	19	8,993,343 (GRCm39)	missense	probably damaging	0.98
R1888:Ahnak	UTSW	19	8,984,452 (GRCm39)	missense	probably damaging	1.00
R1888:Ahnak	UTSW	19	8,984,452 (GRCm39)	missense	probably damaging	1.00
R1912:Ahnak	UTSW	19	8,995,245 (GRCm39)	missense	probably damaging	1.00
R1913:Ahnak	UTSW	19	8,985,286 (GRCm39)	missense	probably damaging	0.99
R1942:Ahnak	UTSW	19	8,992,447 (GRCm39)	missense	probably damaging	0.98
R1987:Ahnak	UTSW	19	8,992,615 (GRCm39)	missense	probably damaging	1.00
R2006:Ahnak	UTSW	19	8,984,439 (GRCm39)	missense	probably damaging	1.00
R2013:Ahnak	UTSW	19	8,991,937 (GRCm39)	missense	probably damaging	0.98
R2014:Ahnak	UTSW	19	8,990,545 (GRCm39)	missense	probably damaging	0.99
R2047:Ahnak	UTSW	19	8,991,664 (GRCm39)	missense	possibly damaging	0.67
R2048:Ahnak	UTSW	19	8,984,420 (GRCm39)	missense	probably damaging	0.99
R2060:Ahnak	UTSW	19	8,985,405 (GRCm39)	missense	probably benign	0.08
R2083:Ahnak	UTSW	19	8,988,921 (GRCm39)	missense	probably damaging	1.00
R2157:Ahnak	UTSW	19	8,978,048 (GRCm39)	missense	possibly damaging	0.92
R2167:Ahnak	UTSW	19	8,988,858 (GRCm39)	nonsense	probably null
R2208:Ahnak	UTSW	19	8,995,096 (GRCm39)	missense	probably benign	0.00
R2224:Ahnak	UTSW	19	8,990,355 (GRCm39)	intron	probably benign
R2268:Ahnak	UTSW	19	8,987,938 (GRCm39)	missense	possibly damaging	0.66
R2420:Ahnak	UTSW	19	8,986,620 (GRCm39)	missense	possibly damaging	0.89
R2426:Ahnak	UTSW	19	8,980,215 (GRCm39)	missense	possibly damaging	0.81
R2910:Ahnak	UTSW	19	8,989,018 (GRCm39)	missense	probably damaging	0.99
R2911:Ahnak	UTSW	19	8,989,018 (GRCm39)	missense	probably damaging	0.99
R2981:Ahnak	UTSW	19	8,977,512 (GRCm39)	missense	probably damaging	0.97
R3151:Ahnak	UTSW	19	8,987,308 (GRCm39)	missense	probably benign	0.12
R3155:Ahnak	UTSW	19	8,987,541 (GRCm39)	missense	possibly damaging	0.49
R3422:Ahnak	UTSW	19	8,984,116 (GRCm39)	missense	probably benign	0.05
R3422:Ahnak	UTSW	19	8,983,072 (GRCm39)	missense	probably benign	0.39
R3430:Ahnak	UTSW	19	8,984,322 (GRCm39)	missense	probably benign	0.42
R3433:Ahnak	UTSW	19	8,987,358 (GRCm39)	missense	probably benign	0.01
R3711:Ahnak	UTSW	19	8,985,262 (GRCm39)	missense	probably benign
R3723:Ahnak	UTSW	19	8,994,217 (GRCm39)	missense	possibly damaging	0.79
R3775:Ahnak	UTSW	19	8,986,387 (GRCm39)	missense	possibly damaging	0.91
R3858:Ahnak	UTSW	19	8,988,223 (GRCm39)	missense	possibly damaging	0.82
R3859:Ahnak	UTSW	19	8,988,223 (GRCm39)	missense	possibly damaging	0.82
R3922:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R3924:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R3926:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R4026:Ahnak	UTSW	19	8,988,663 (GRCm39)	missense	probably damaging	0.97
R4051:Ahnak	UTSW	19	8,991,691 (GRCm39)	missense	probably damaging	1.00
R4209:Ahnak	UTSW	19	8,979,964 (GRCm39)	missense	probably damaging	1.00
R4234:Ahnak	UTSW	19	8,978,150 (GRCm39)	nonsense	probably null
R4237:Ahnak	UTSW	19	8,979,147 (GRCm39)	missense	probably benign	0.02
R4285:Ahnak	UTSW	19	8,994,203 (GRCm39)	nonsense	probably null
R4331:Ahnak	UTSW	19	8,993,184 (GRCm39)	missense	probably damaging	1.00
R4342:Ahnak	UTSW	19	8,989,447 (GRCm39)	missense	possibly damaging	0.79
R4430:Ahnak	UTSW	19	8,980,404 (GRCm39)	missense	probably benign	0.00
R4554:Ahnak	UTSW	19	8,992,294 (GRCm39)	missense	probably damaging	1.00
R4602:Ahnak	UTSW	19	8,988,189 (GRCm39)	missense	possibly damaging	0.66
R4612:Ahnak	UTSW	19	8,981,088 (GRCm39)	missense	probably benign	0.44
R4655:Ahnak	UTSW	19	8,986,065 (GRCm39)	missense	probably damaging	1.00
R4656:Ahnak	UTSW	19	8,982,219 (GRCm39)	missense	possibly damaging	0.80
R4700:Ahnak	UTSW	19	8,982,045 (GRCm39)	missense	probably benign	0.02
R4704:Ahnak	UTSW	19	8,989,622 (GRCm39)	intron	probably benign
R4704:Ahnak	UTSW	19	8,990,545 (GRCm39)	missense	probably damaging	0.99
R4705:Ahnak	UTSW	19	8,994,270 (GRCm39)	missense	probably benign	0.07
R4707:Ahnak	UTSW	19	8,994,099 (GRCm39)	missense	probably benign	0.03
R4732:Ahnak	UTSW	19	8,984,665 (GRCm39)	missense	probably damaging	1.00
R4733:Ahnak	UTSW	19	8,984,665 (GRCm39)	missense	probably damaging	1.00
R4778:Ahnak	UTSW	19	8,989,339 (GRCm39)	missense	possibly damaging	0.79
R4782:Ahnak	UTSW	19	8,989,863 (GRCm39)	intron	probably benign
R4832:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R4882:Ahnak	UTSW	19	8,983,261 (GRCm39)	missense	probably damaging	0.98
R4884:Ahnak	UTSW	19	8,990,118 (GRCm39)	intron	probably benign
R4895:Ahnak	UTSW	19	8,994,805 (GRCm39)	missense	probably benign	0.43
R4930:Ahnak	UTSW	19	8,988,331 (GRCm39)	missense	possibly damaging	0.79
R4951:Ahnak	UTSW	19	8,995,199 (GRCm39)	missense	probably damaging	1.00
R4968:Ahnak	UTSW	19	8,992,464 (GRCm39)	missense	probably damaging	1.00
R5026:Ahnak	UTSW	19	8,987,995 (GRCm39)	missense	possibly damaging	0.46
R5050:Ahnak	UTSW	19	8,989,822 (GRCm39)	intron	probably benign
R5073:Ahnak	UTSW	19	8,980,595 (GRCm39)	missense	probably benign	0.42
R5110:Ahnak	UTSW	19	8,992,123 (GRCm39)	missense	probably damaging	1.00
R5119:Ahnak	UTSW	19	8,991,008 (GRCm39)	missense	probably benign	0.00
R5128:Ahnak	UTSW	19	8,994,451 (GRCm39)	missense	probably damaging	1.00
R5139:Ahnak	UTSW	19	8,982,019 (GRCm39)	missense	probably damaging	1.00
R5150:Ahnak	UTSW	19	8,988,268 (GRCm39)	missense	possibly damaging	0.46
R5151:Ahnak	UTSW	19	8,994,933 (GRCm39)	missense	probably benign	0.03
R5165:Ahnak	UTSW	19	8,993,029 (GRCm39)	missense	possibly damaging	0.95
R5236:Ahnak	UTSW	19	8,978,048 (GRCm39)	missense	possibly damaging	0.92
R5361:Ahnak	UTSW	19	8,992,705 (GRCm39)	missense	possibly damaging	0.92
R5366:Ahnak	UTSW	19	8,994,099 (GRCm39)	missense	possibly damaging	0.65
R5387:Ahnak	UTSW	19	8,981,055 (GRCm39)	missense	probably damaging	1.00
R5396:Ahnak	UTSW	19	8,984,539 (GRCm39)	missense	probably damaging	0.99
R5583:Ahnak	UTSW	19	8,984,281 (GRCm39)	missense	probably damaging	0.99
R5587:Ahnak	UTSW	19	8,986,840 (GRCm39)	missense	possibly damaging	0.88
R5620:Ahnak	UTSW	19	8,990,458 (GRCm39)	nonsense	probably null
R5643:Ahnak	UTSW	19	8,988,021 (GRCm39)	missense	possibly damaging	0.66
R5644:Ahnak	UTSW	19	8,988,021 (GRCm39)	missense	possibly damaging	0.66
R5657:Ahnak	UTSW	19	8,991,979 (GRCm39)	missense	probably damaging	0.99
R5688:Ahnak	UTSW	19	8,979,883 (GRCm39)	missense	probably benign	0.01
R5702:Ahnak	UTSW	19	8,979,204 (GRCm39)	missense	probably damaging	1.00
R5727:Ahnak	UTSW	19	8,994,111 (GRCm39)	missense	probably damaging	0.99
R5730:Ahnak	UTSW	19	8,987,617 (GRCm39)	missense	possibly damaging	0.81
R5755:Ahnak	UTSW	19	8,979,096 (GRCm39)	missense	probably benign	0.06
R5760:Ahnak	UTSW	19	8,990,926 (GRCm39)	missense	probably damaging	1.00
R5789:Ahnak	UTSW	19	8,979,685 (GRCm39)	missense	probably benign	0.00
R5790:Ahnak	UTSW	19	8,992,612 (GRCm39)	missense	probably damaging	0.99
R5795:Ahnak	UTSW	19	8,989,746 (GRCm39)	nonsense	probably null
R5808:Ahnak	UTSW	19	8,987,599 (GRCm39)	missense	possibly damaging	0.91
R5867:Ahnak	UTSW	19	8,987,416 (GRCm39)	missense	probably damaging	0.99
R5878:Ahnak	UTSW	19	8,985,706 (GRCm39)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	8,995,575 (GRCm39)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	8,991,131 (GRCm39)	missense	possibly damaging	0.63
R5912:Ahnak	UTSW	19	8,989,267 (GRCm39)	missense	probably damaging	0.99
R5935:Ahnak	UTSW	19	8,992,546 (GRCm39)	missense	possibly damaging	0.91
R5969:Ahnak	UTSW	19	8,993,949 (GRCm39)	missense	probably damaging	1.00
R5988:Ahnak	UTSW	19	8,986,711 (GRCm39)	intron	probably benign
R6000:Ahnak	UTSW	19	8,990,475 (GRCm39)	nonsense	probably null
R6005:Ahnak	UTSW	19	8,992,525 (GRCm39)	missense	possibly damaging	0.61
R6101:Ahnak	UTSW	19	8,981,463 (GRCm39)	missense	probably benign	0.20
R6105:Ahnak	UTSW	19	8,981,463 (GRCm39)	missense	probably benign	0.20
R6116:Ahnak	UTSW	19	8,990,327 (GRCm39)	intron	probably benign
R6209:Ahnak	UTSW	19	8,989,930 (GRCm39)	missense	probably damaging	1.00
R6240:Ahnak	UTSW	19	8,990,947 (GRCm39)	missense	probably damaging	1.00
R6255:Ahnak	UTSW	19	8,985,389 (GRCm39)	missense	possibly damaging	0.95
R6263:Ahnak	UTSW	19	8,995,641 (GRCm39)	missense	probably benign	0.03
R6287:Ahnak	UTSW	19	8,992,367 (GRCm39)	missense	probably benign	0.02
R6296:Ahnak	UTSW	19	8,980,669 (GRCm39)	missense	probably damaging	0.99
R6315:Ahnak	UTSW	19	8,983,990 (GRCm39)	missense	probably damaging	0.99
R6328:Ahnak	UTSW	19	8,984,512 (GRCm39)	missense	probably benign	0.11
R6331:Ahnak	UTSW	19	8,983,989 (GRCm39)	missense	probably benign	0.18
R6355:Ahnak	UTSW	19	8,986,126 (GRCm39)	missense	probably benign	0.02
R6409:Ahnak	UTSW	19	8,986,938 (GRCm39)	missense	probably benign	0.31
R6567:Ahnak	UTSW	19	8,986,170 (GRCm39)	missense	probably benign	0.27
R6572:Ahnak	UTSW	19	8,985,340 (GRCm39)	missense	probably damaging	0.99
R6574:Ahnak	UTSW	19	8,994,411 (GRCm39)	missense	probably benign	0.04
R6590:Ahnak	UTSW	19	8,986,945 (GRCm39)	missense	probably benign	0.29
R6620:Ahnak	UTSW	19	8,992,674 (GRCm39)	missense	possibly damaging	0.95
R6690:Ahnak	UTSW	19	8,986,945 (GRCm39)	missense	probably benign	0.29
R6731:Ahnak	UTSW	19	8,988,926 (GRCm39)	missense	possibly damaging	0.85
R6756:Ahnak	UTSW	19	8,984,925 (GRCm39)	missense	possibly damaging	0.59
R6846:Ahnak	UTSW	19	8,989,221 (GRCm39)	missense	possibly damaging	0.66
R6854:Ahnak	UTSW	19	8,992,599 (GRCm39)	missense	probably damaging	1.00
R6857:Ahnak	UTSW	19	9,014,532 (GRCm39)	nonsense	probably null
R6863:Ahnak	UTSW	19	8,989,729 (GRCm39)	intron	probably benign
R6876:Ahnak	UTSW	19	8,991,484 (GRCm39)	missense	probably damaging	0.99
R6958:Ahnak	UTSW	19	8,992,579 (GRCm39)	missense	possibly damaging	0.88
R7126:Ahnak	UTSW	19	8,979,723 (GRCm39)	missense	possibly damaging	0.61
R7181:Ahnak	UTSW	19	8,990,852 (GRCm39)	missense	probably damaging	1.00
R7183:Ahnak	UTSW	19	8,995,032 (GRCm39)	missense	probably damaging	1.00
R7202:Ahnak	UTSW	19	8,995,163 (GRCm39)	missense	probably damaging	1.00
R7235:Ahnak	UTSW	19	8,989,852 (GRCm39)	missense	unknown
R7241:Ahnak	UTSW	19	8,986,395 (GRCm39)	missense	possibly damaging	0.65
R7269:Ahnak	UTSW	19	8,983,981 (GRCm39)	missense	probably damaging	1.00
R7311:Ahnak	UTSW	19	8,979,507 (GRCm39)	missense	probably benign	0.04
R7311:Ahnak	UTSW	19	8,987,191 (GRCm39)	missense	possibly damaging	0.56
R7329:Ahnak	UTSW	19	8,979,156 (GRCm39)	missense	probably damaging	0.99
R7339:Ahnak	UTSW	19	8,985,529 (GRCm39)	missense	possibly damaging	0.75
R7390:Ahnak	UTSW	19	8,980,569 (GRCm39)	missense	probably benign	0.02
R7400:Ahnak	UTSW	19	8,991,977 (GRCm39)	missense	probably damaging	0.99
R7444:Ahnak	UTSW	19	8,984,787 (GRCm39)	missense	probably benign	0.08
R7483:Ahnak	UTSW	19	8,982,186 (GRCm39)	missense	probably damaging	1.00
R7498:Ahnak	UTSW	19	8,989,383 (GRCm39)	missense	probably benign	0.14
R7521:Ahnak	UTSW	19	8,979,715 (GRCm39)	missense	possibly damaging	0.89
R7522:Ahnak	UTSW	19	8,979,686 (GRCm39)	missense	probably benign	0.01
R7552:Ahnak	UTSW	19	8,984,188 (GRCm39)	missense	probably benign	0.18
R7563:Ahnak	UTSW	19	8,988,529 (GRCm39)	missense	probably damaging	0.99
R7565:Ahnak	UTSW	19	8,993,520 (GRCm39)	missense	probably benign	0.05
R7571:Ahnak	UTSW	19	8,978,150 (GRCm39)	nonsense	probably null
R7583:Ahnak	UTSW	19	8,983,457 (GRCm39)	missense	possibly damaging	0.90
R7600:Ahnak	UTSW	19	8,981,938 (GRCm39)	missense	possibly damaging	0.89
R7771:Ahnak	UTSW	19	8,992,411 (GRCm39)	missense	probably damaging	0.99
R7787:Ahnak	UTSW	19	8,986,679 (GRCm39)	missense	unknown
R7827:Ahnak	UTSW	19	8,982,708 (GRCm39)	nonsense	probably null
R7857:Ahnak	UTSW	19	8,984,832 (GRCm39)	missense	probably damaging	0.97
R7916:Ahnak	UTSW	19	8,983,196 (GRCm39)	missense	possibly damaging	0.66
R7939:Ahnak	UTSW	19	8,991,448 (GRCm39)	nonsense	probably null
R7959:Ahnak	UTSW	19	8,988,013 (GRCm39)	missense	possibly damaging	0.46
R7962:Ahnak	UTSW	19	8,990,164 (GRCm39)	missense	unknown
R7979:Ahnak	UTSW	19	8,988,796 (GRCm39)	missense	probably damaging	1.00
R8006:Ahnak	UTSW	19	8,989,447 (GRCm39)	missense	possibly damaging	0.79
R8013:Ahnak	UTSW	19	8,986,699 (GRCm39)	missense	unknown
R8033:Ahnak	UTSW	19	8,981,074 (GRCm39)	missense	probably benign	0.10
R8124:Ahnak	UTSW	19	8,984,487 (GRCm39)	missense	probably damaging	0.99
R8125:Ahnak	UTSW	19	8,989,240 (GRCm39)	missense	possibly damaging	0.95
R8129:Ahnak	UTSW	19	8,977,464 (GRCm39)	start codon destroyed	not run
R8151:Ahnak	UTSW	19	8,982,043 (GRCm39)	missense	possibly damaging	0.59
R8190:Ahnak	UTSW	19	8,979,619 (GRCm39)	missense	probably benign	0.01
R8221:Ahnak	UTSW	19	8,987,800 (GRCm39)	nonsense	probably null
R8241:Ahnak	UTSW	19	8,984,659 (GRCm39)	missense	probably benign	0.15
R8244:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8248:Ahnak	UTSW	19	8,979,310 (GRCm39)	missense	probably damaging	1.00
R8261:Ahnak	UTSW	19	8,982,817 (GRCm39)	missense	probably damaging	1.00
R8330:Ahnak	UTSW	19	8,987,026 (GRCm39)	missense	possibly damaging	0.86
R8380:Ahnak	UTSW	19	8,995,219 (GRCm39)	missense	probably benign	0.05
R8407:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8409:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8463:Ahnak	UTSW	19	8,986,113 (GRCm39)	missense	probably benign	0.07
R8511:Ahnak	UTSW	19	8,989,719 (GRCm39)	missense	unknown
R8528:Ahnak	UTSW	19	8,985,092 (GRCm39)	missense	probably damaging	1.00
R8549:Ahnak	UTSW	19	8,988,847 (GRCm39)	missense	probably damaging	1.00
R8674:Ahnak	UTSW	19	8,983,360 (GRCm39)	missense	probably damaging	0.98
R8716:Ahnak	UTSW	19	8,986,438 (GRCm39)	missense	probably damaging	1.00
R8722:Ahnak	UTSW	19	8,990,710 (GRCm39)	nonsense	probably null
R8751:Ahnak	UTSW	19	8,987,509 (GRCm39)	missense	probably damaging	1.00
R8752:Ahnak	UTSW	19	8,992,901 (GRCm39)	missense	probably damaging	1.00
R8783:Ahnak	UTSW	19	8,988,837 (GRCm39)	missense	probably damaging	1.00
R8844:Ahnak	UTSW	19	8,984,254 (GRCm39)	missense	probably damaging	1.00
R8859:Ahnak	UTSW	19	8,984,567 (GRCm39)	missense	probably damaging	1.00
R8882:Ahnak	UTSW	19	8,978,106 (GRCm39)	missense	probably damaging	1.00
R8907:Ahnak	UTSW	19	8,986,452 (GRCm39)	missense	probably benign	0.24
R8938:Ahnak	UTSW	19	8,989,099 (GRCm39)	missense	probably benign	0.00
R8975:Ahnak	UTSW	19	8,990,101 (GRCm39)	missense	probably damaging	1.00
R8983:Ahnak	UTSW	19	8,981,477 (GRCm39)	missense	possibly damaging	0.75
R9017:Ahnak	UTSW	19	8,987,487 (GRCm39)	missense	probably damaging	1.00
R9027:Ahnak	UTSW	19	8,984,617 (GRCm39)	missense	possibly damaging	0.94
R9081:Ahnak	UTSW	19	8,985,890 (GRCm39)	missense	possibly damaging	0.81
R9104:Ahnak	UTSW	19	8,987,711 (GRCm39)	missense	probably benign	0.01
R9112:Ahnak	UTSW	19	8,987,149 (GRCm39)	missense	probably damaging	0.98
R9145:Ahnak	UTSW	19	8,992,287 (GRCm39)	missense	probably benign	0.38
R9189:Ahnak	UTSW	19	8,988,247 (GRCm39)	missense	possibly damaging	0.92
R9221:Ahnak	UTSW	19	8,989,943 (GRCm39)	missense	probably damaging	1.00
R9261:Ahnak	UTSW	19	8,993,503 (GRCm39)	missense	possibly damaging	0.63
R9299:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R9325:Ahnak	UTSW	19	8,991,257 (GRCm39)	missense	probably benign	0.12
R9337:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R9351:Ahnak	UTSW	19	8,985,232 (GRCm39)	missense	probably damaging	1.00
R9416:Ahnak	UTSW	19	8,990,266 (GRCm39)	missense	unknown
R9462:Ahnak	UTSW	19	8,981,299 (GRCm39)	missense	probably damaging	0.96
R9469:Ahnak	UTSW	19	8,988,225 (GRCm39)	missense	probably damaging	1.00
R9485:Ahnak	UTSW	19	8,979,438 (GRCm39)	missense	probably benign	0.16
R9503:Ahnak	UTSW	19	8,987,458 (GRCm39)	missense	probably damaging	1.00
R9524:Ahnak	UTSW	19	9,014,617 (GRCm39)	missense
R9534:Ahnak	UTSW	19	8,980,976 (GRCm39)	missense	probably benign	0.20
R9598:Ahnak	UTSW	19	8,981,149 (GRCm39)	missense	probably benign	0.42
R9611:Ahnak	UTSW	19	8,989,162 (GRCm39)	missense	probably damaging	0.99
R9624:Ahnak	UTSW	19	8,989,846 (GRCm39)	missense	unknown
R9649:Ahnak	UTSW	19	8,985,786 (GRCm39)	nonsense	probably null
R9683:Ahnak	UTSW	19	8,984,719 (GRCm39)	missense	possibly damaging	0.94
R9691:Ahnak	UTSW	19	8,989,090 (GRCm39)	missense	possibly damaging	0.49
R9712:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9712:Ahnak	UTSW	19	8,984,392 (GRCm39)	small deletion	probably benign
R9713:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9715:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9725:Ahnak	UTSW	19	8,991,607 (GRCm39)	missense	probably damaging	1.00
R9725:Ahnak	UTSW	19	8,981,533 (GRCm39)	missense	probably benign	0.44
R9747:Ahnak	UTSW	19	8,987,541 (GRCm39)	missense	possibly damaging	0.49
R9798:Ahnak	UTSW	19	8,990,983 (GRCm39)	missense	probably damaging	0.99
RF007:Ahnak	UTSW	19	8,990,965 (GRCm39)	missense	possibly damaging	0.45
X0021:Ahnak	UTSW	19	8,990,983 (GRCm39)	missense	probably damaging	0.99
X0027:Ahnak	UTSW	19	8,989,401 (GRCm39)	missense	probably damaging	1.00
Z1088:Ahnak	UTSW	19	8,993,446 (GRCm39)	missense	probably damaging	0.99
Z1176:Ahnak	UTSW	19	8,986,220 (GRCm39)	missense	probably damaging	0.97
Z1177:Ahnak	UTSW	19	8,994,832 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TGTCCTAAAGTGTCTGTGGC -3'
(R):5'- ATTTCGGGACCAGAAATCTGCC -3'

Sequencing Primer
(F):5'- AAAGTGTCTGTGGCTACTCC -3'
(R):5'- CAGAAATCTGCCCTGATGAGAGTTTC -3'

Posted On

2022-04-18