Incidental Mutation 'R9342:Prdm2'
| ID |
707551 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prdm2
|
| Ensembl Gene |
ENSMUSG00000057637 |
| Gene Name |
PR domain containing 2, with ZNF domain |
| Synonyms |
KMT8, LOC381568, Riz, E330024L24Rik, 4833427P12Rik, Riz1 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9342 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
142833961-142939560 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 142861478 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 604
(I604T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101404
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000105778]
|
| AlphaFold |
A2A7B5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105778
AA Change: I604T
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000101404
Gene: ENSMUSG00000057637
AA Change: I604T
| Domain | Start | End | E-Value | Type |
|---|
|
SET
|
29 |
146 |
2.79e-21 |
SMART |
|
coiled coil region
|
254 |
293 |
N/A |
INTRINSIC |
|
low complexity region
|
333 |
346 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
356 |
378 |
2.95e-3 |
SMART |
|
ZnF_C2H2
|
386 |
408 |
4.79e-3 |
SMART |
|
ZnF_C2H2
|
477 |
500 |
4.17e-3 |
SMART |
|
low complexity region
|
517 |
528 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
682 |
697 |
N/A |
INTRINSIC |
|
low complexity region
|
726 |
744 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
877 |
N/A |
INTRINSIC |
|
low complexity region
|
931 |
951 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
992 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1032 |
N/A |
INTRINSIC |
|
low complexity region
|
1035 |
1080 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1126 |
1148 |
3.52e-1 |
SMART |
|
ZnF_C2H2
|
1154 |
1177 |
7.55e-1 |
SMART |
|
ZnF_C2H2
|
1183 |
1206 |
4.72e-2 |
SMART |
|
low complexity region
|
1239 |
1253 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1324 |
1344 |
5.12e1 |
SMART |
|
low complexity region
|
1406 |
1423 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1446 |
1466 |
1.86e1 |
SMART |
|
low complexity region
|
1475 |
1507 |
N/A |
INTRINSIC |
|
low complexity region
|
1551 |
1568 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
PHENOTYPE: Homozygous null mice have shortened life spans, becoming moribund due to increased incidence of tumors. Mice had a broad spectrum of unusual tumors in multiple organs, with a high incidence of diffuse large B cell lymphomas. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A330070K13Rik |
T |
C |
5: 130,407,876 (GRCm39) |
I112V |
unknown |
Het |
| Aars2 |
A |
G |
17: 45,818,002 (GRCm39) |
N75D |
possibly damaging |
Het |
| Abcf2 |
G |
A |
5: 24,778,475 (GRCm39) |
R228C |
probably benign |
Het |
| Agfg2 |
A |
G |
5: 137,652,114 (GRCm39) |
L415P |
probably benign |
Het |
| Alpi |
A |
G |
1: 87,026,386 (GRCm39) |
L535P |
unknown |
Het |
| Anxa9 |
T |
G |
3: 95,210,359 (GRCm39) |
T69P |
probably damaging |
Het |
| Arrb2 |
T |
A |
11: 70,327,463 (GRCm39) |
D79E |
probably benign |
Het |
| Bcat1 |
A |
G |
6: 144,994,332 (GRCm39) |
V55A |
probably benign |
Het |
| Cacna1c |
A |
G |
6: 119,034,335 (GRCm39) |
L64P |
|
Het |
| Cd247 |
A |
T |
1: 165,682,759 (GRCm39) |
D28V |
probably damaging |
Het |
| Celsr2 |
T |
A |
3: 108,320,442 (GRCm39) |
N790I |
probably damaging |
Het |
| Clrn1 |
C |
T |
3: 58,792,251 (GRCm39) |
V71I |
probably benign |
Het |
| Cmtr2 |
T |
C |
8: 110,949,078 (GRCm39) |
Y463H |
possibly damaging |
Het |
| Col6a6 |
T |
C |
9: 105,663,172 (GRCm39) |
T122A |
probably benign |
Het |
| Cubn |
T |
A |
2: 13,463,767 (GRCm39) |
D646V |
probably damaging |
Het |
| Dab2ip |
T |
A |
2: 35,613,105 (GRCm39) |
L1062Q |
possibly damaging |
Het |
| Dnajb4 |
T |
C |
3: 151,892,272 (GRCm39) |
N187S |
probably benign |
Het |
| Dock10 |
A |
T |
1: 80,570,360 (GRCm39) |
F365L |
probably benign |
Het |
| Erich6 |
G |
A |
3: 58,534,101 (GRCm39) |
Q309* |
probably null |
Het |
| Ext1 |
T |
C |
15: 53,208,524 (GRCm39) |
H79R |
probably benign |
Het |
| Fam187b |
T |
A |
7: 30,677,185 (GRCm39) |
C231* |
probably null |
Het |
| Fbh1 |
T |
C |
2: 11,754,414 (GRCm39) |
I775V |
probably benign |
Het |
| Fbxo15 |
T |
A |
18: 84,983,609 (GRCm39) |
M319K |
unknown |
Het |
| Fbxo9 |
A |
T |
9: 78,002,520 (GRCm39) |
M187K |
possibly damaging |
Het |
| Fer1l4 |
T |
C |
2: 155,877,196 (GRCm39) |
D1113G |
probably benign |
Het |
| Fsip2 |
A |
T |
2: 82,818,747 (GRCm39) |
T4827S |
possibly damaging |
Het |
| Gm49398 |
A |
T |
13: 61,435,478 (GRCm39) |
L7Q |
probably damaging |
Het |
| H2-M10.4 |
A |
T |
17: 36,771,285 (GRCm39) |
W298R |
probably damaging |
Het |
| Hoxd10 |
A |
G |
2: 74,522,982 (GRCm39) |
E220G |
probably benign |
Het |
| Hrh2 |
T |
G |
13: 54,368,222 (GRCm39) |
L66R |
probably damaging |
Het |
| Igf1r |
A |
G |
7: 67,844,746 (GRCm39) |
T840A |
probably benign |
Het |
| Iqca1 |
A |
G |
1: 90,072,688 (GRCm39) |
V64A |
probably damaging |
Het |
| Klc2 |
A |
G |
19: 5,158,659 (GRCm39) |
S612P |
probably benign |
Het |
| Klf15 |
A |
G |
6: 90,443,851 (GRCm39) |
E142G |
probably damaging |
Het |
| Krt40 |
T |
A |
11: 99,429,579 (GRCm39) |
T332S |
probably damaging |
Het |
| Lrrc9 |
T |
C |
12: 72,506,767 (GRCm39) |
F348S |
probably damaging |
Het |
| Lrrn4 |
T |
C |
2: 132,712,290 (GRCm39) |
D511G |
probably benign |
Het |
| Lrtm2 |
T |
C |
6: 119,297,934 (GRCm39) |
I36V |
probably benign |
Het |
| Lsm10 |
T |
C |
4: 125,991,860 (GRCm39) |
L72P |
probably damaging |
Het |
| Mab21l3 |
T |
A |
3: 101,742,519 (GRCm39) |
S14C |
possibly damaging |
Het |
| Map2k4 |
T |
C |
11: 65,581,569 (GRCm39) |
K381R |
probably benign |
Het |
| Mcidas |
A |
G |
13: 113,130,915 (GRCm39) |
D80G |
probably damaging |
Het |
| Med23 |
A |
G |
10: 24,750,469 (GRCm39) |
M99V |
probably benign |
Het |
| Mga |
A |
G |
2: 119,778,656 (GRCm39) |
D2067G |
probably benign |
Het |
| Ms4a19 |
T |
A |
19: 11,119,775 (GRCm39) |
T52S |
possibly damaging |
Het |
| Msc |
G |
T |
1: 14,825,707 (GRCm39) |
P89Q |
probably benign |
Het |
| Nalf1 |
C |
A |
8: 9,821,006 (GRCm39) |
A5S |
probably damaging |
Het |
| Or14c44 |
A |
G |
7: 86,062,430 (GRCm39) |
I287V |
probably benign |
Het |
| Or2d3c |
A |
T |
7: 106,526,564 (GRCm39) |
I34N |
possibly damaging |
Het |
| Or5t7 |
A |
T |
2: 86,507,494 (GRCm39) |
L61Q |
probably damaging |
Het |
| Plekhg6 |
T |
C |
6: 125,340,023 (GRCm39) |
D779G |
probably damaging |
Het |
| Pnpla2 |
C |
A |
7: 141,035,331 (GRCm39) |
Y44* |
probably null |
Het |
| Ppp1r17 |
T |
A |
6: 56,003,524 (GRCm39) |
D112E |
probably damaging |
Het |
| Prkce |
A |
G |
17: 86,781,877 (GRCm39) |
Y182C |
probably damaging |
Het |
| Prokr2 |
G |
A |
2: 132,182,790 (GRCm39) |
S189F |
possibly damaging |
Het |
| Qser1 |
A |
T |
2: 104,618,164 (GRCm39) |
S793T |
probably benign |
Het |
| Reck |
T |
C |
4: 43,943,301 (GRCm39) |
F951S |
probably benign |
Het |
| Rev3l |
T |
C |
10: 39,697,458 (GRCm39) |
S652P |
probably benign |
Het |
| Rtl1 |
A |
C |
12: 109,558,884 (GRCm39) |
L985R |
probably damaging |
Het |
| Sardh |
T |
C |
2: 27,120,869 (GRCm39) |
E385G |
possibly damaging |
Het |
| Sfmbt1 |
G |
T |
14: 30,519,599 (GRCm39) |
W440L |
possibly damaging |
Het |
| Slc4a7 |
T |
A |
14: 14,772,541 (GRCm38) |
C683* |
probably null |
Het |
| Slc51a |
A |
G |
16: 32,298,517 (GRCm39) |
L80P |
possibly damaging |
Het |
| Slco3a1 |
C |
A |
7: 74,154,037 (GRCm39) |
L178F |
probably damaging |
Het |
| Spata6 |
T |
A |
4: 111,636,389 (GRCm39) |
C227S |
possibly damaging |
Het |
| Tbc1d30 |
A |
T |
10: 121,103,366 (GRCm39) |
Y555* |
probably null |
Het |
| Tcf7l2 |
A |
G |
19: 55,731,517 (GRCm39) |
Q90R |
probably benign |
Het |
| Tff3 |
A |
C |
17: 31,346,423 (GRCm39) |
S50A |
probably benign |
Het |
| Tnrc6c |
T |
C |
11: 117,630,720 (GRCm39) |
M1027T |
probably benign |
Het |
| Ttc12 |
A |
G |
9: 49,351,680 (GRCm39) |
F606L |
probably benign |
Het |
| Uqcc3 |
G |
A |
19: 8,858,090 (GRCm39) |
Q34* |
probably null |
Het |
| Veph1 |
T |
A |
3: 66,151,959 (GRCm39) |
I157F |
probably damaging |
Het |
| Vmn2r14 |
G |
A |
5: 109,368,428 (GRCm39) |
T188I |
probably damaging |
Het |
| Vmn2r67 |
A |
G |
7: 84,785,788 (GRCm39) |
I739T |
probably benign |
Het |
| Vmn2r68 |
A |
G |
7: 84,882,993 (GRCm39) |
F253S |
probably benign |
Het |
| Vmn2r74 |
T |
C |
7: 85,606,624 (GRCm39) |
I241V |
probably benign |
Het |
| Vmn2r97 |
A |
G |
17: 19,149,368 (GRCm39) |
E252G |
probably benign |
Het |
| Vps13b |
T |
C |
15: 35,455,200 (GRCm39) |
V703A |
possibly damaging |
Het |
| Vps25 |
T |
A |
11: 101,149,623 (GRCm39) |
L149Q |
probably damaging |
Het |
| Xirp1 |
T |
C |
9: 119,845,950 (GRCm39) |
T978A |
probably benign |
Het |
| Xpnpep1 |
T |
A |
19: 52,993,248 (GRCm39) |
I360F |
probably benign |
Het |
| Zfpm1 |
C |
T |
8: 123,061,308 (GRCm39) |
T291M |
probably benign |
Het |
| Zkscan8 |
A |
G |
13: 21,710,702 (GRCm39) |
V136A |
probably benign |
Het |
| Zscan18 |
A |
G |
7: 12,505,612 (GRCm39) |
Y592H |
probably damaging |
Het |
|
| Other mutations in Prdm2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00530:Prdm2
|
APN |
4 |
142,860,329 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00843:Prdm2
|
APN |
4 |
142,860,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01419:Prdm2
|
APN |
4 |
142,860,218 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01662:Prdm2
|
APN |
4 |
142,860,138 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01892:Prdm2
|
APN |
4 |
142,860,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02104:Prdm2
|
APN |
4 |
142,859,997 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02208:Prdm2
|
APN |
4 |
142,862,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02260:Prdm2
|
APN |
4 |
142,861,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02479:Prdm2
|
APN |
4 |
142,861,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Prdm2
|
APN |
4 |
142,858,542 (GRCm39) |
missense |
probably benign |
|
|
IGL02972:Prdm2
|
APN |
4 |
142,858,736 (GRCm39) |
missense |
probably benign |
|
|
IGL03038:Prdm2
|
APN |
4 |
142,860,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03399:Prdm2
|
APN |
4 |
142,861,658 (GRCm39) |
missense |
probably benign |
0.07 |
|
G1patch:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
PIT4677001:Prdm2
|
UTSW |
4 |
142,861,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0088:Prdm2
|
UTSW |
4 |
142,861,524 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0153:Prdm2
|
UTSW |
4 |
142,860,338 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0320:Prdm2
|
UTSW |
4 |
142,905,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0384:Prdm2
|
UTSW |
4 |
142,862,258 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0400:Prdm2
|
UTSW |
4 |
142,838,240 (GRCm39) |
missense |
probably benign |
|
|
R0658:Prdm2
|
UTSW |
4 |
142,861,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0850:Prdm2
|
UTSW |
4 |
142,858,773 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1118:Prdm2
|
UTSW |
4 |
142,858,953 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R1355:Prdm2
|
UTSW |
4 |
142,858,533 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1519:Prdm2
|
UTSW |
4 |
142,862,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1936:Prdm2
|
UTSW |
4 |
142,861,032 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1987:Prdm2
|
UTSW |
4 |
142,859,079 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2006:Prdm2
|
UTSW |
4 |
142,858,447 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2008:Prdm2
|
UTSW |
4 |
142,861,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2030:Prdm2
|
UTSW |
4 |
142,859,334 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R2112:Prdm2
|
UTSW |
4 |
142,858,506 (GRCm39) |
missense |
probably benign |
|
|
R2221:Prdm2
|
UTSW |
4 |
142,861,469 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2223:Prdm2
|
UTSW |
4 |
142,861,469 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2426:Prdm2
|
UTSW |
4 |
142,838,320 (GRCm39) |
nonsense |
probably null |
|
|
R2430:Prdm2
|
UTSW |
4 |
142,859,733 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2484:Prdm2
|
UTSW |
4 |
142,861,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Prdm2
|
UTSW |
4 |
142,860,929 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Prdm2
|
UTSW |
4 |
142,858,385 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4209:Prdm2
|
UTSW |
4 |
142,861,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4411:Prdm2
|
UTSW |
4 |
142,860,240 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4647:Prdm2
|
UTSW |
4 |
142,859,525 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4898:Prdm2
|
UTSW |
4 |
142,860,761 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Prdm2
|
UTSW |
4 |
142,905,937 (GRCm39) |
nonsense |
probably null |
|
|
R5181:Prdm2
|
UTSW |
4 |
142,861,536 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5513:Prdm2
|
UTSW |
4 |
142,862,463 (GRCm39) |
small deletion |
probably benign |
|
|
R5539:Prdm2
|
UTSW |
4 |
142,859,264 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5563:Prdm2
|
UTSW |
4 |
142,861,200 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5618:Prdm2
|
UTSW |
4 |
142,860,107 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5900:Prdm2
|
UTSW |
4 |
142,861,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5990:Prdm2
|
UTSW |
4 |
142,896,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6148:Prdm2
|
UTSW |
4 |
142,859,477 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6166:Prdm2
|
UTSW |
4 |
142,861,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6223:Prdm2
|
UTSW |
4 |
142,868,777 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6530:Prdm2
|
UTSW |
4 |
142,860,617 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6631:Prdm2
|
UTSW |
4 |
142,861,454 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6725:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6847:Prdm2
|
UTSW |
4 |
142,859,520 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7193:Prdm2
|
UTSW |
4 |
142,907,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Prdm2
|
UTSW |
4 |
142,862,391 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7292:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7417:Prdm2
|
UTSW |
4 |
142,905,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7748:Prdm2
|
UTSW |
4 |
142,862,459 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7885:Prdm2
|
UTSW |
4 |
142,861,140 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7936:Prdm2
|
UTSW |
4 |
142,862,434 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7976:Prdm2
|
UTSW |
4 |
142,859,812 (GRCm39) |
nonsense |
probably null |
|
|
R8124:Prdm2
|
UTSW |
4 |
142,861,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Prdm2
|
UTSW |
4 |
142,859,303 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8156:Prdm2
|
UTSW |
4 |
142,861,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8178:Prdm2
|
UTSW |
4 |
142,859,018 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8235:Prdm2
|
UTSW |
4 |
142,859,037 (GRCm39) |
nonsense |
probably null |
|
|
R8404:Prdm2
|
UTSW |
4 |
142,861,584 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8498:Prdm2
|
UTSW |
4 |
142,907,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8502:Prdm2
|
UTSW |
4 |
142,861,584 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8688:Prdm2
|
UTSW |
4 |
142,838,310 (GRCm39) |
missense |
probably benign |
|
|
R8732:Prdm2
|
UTSW |
4 |
142,862,580 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8796:Prdm2
|
UTSW |
4 |
142,860,017 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8874:Prdm2
|
UTSW |
4 |
142,859,785 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8887:Prdm2
|
UTSW |
4 |
142,860,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9119:Prdm2
|
UTSW |
4 |
142,858,449 (GRCm39) |
nonsense |
probably null |
|
|
R9139:Prdm2
|
UTSW |
4 |
142,858,752 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9165:Prdm2
|
UTSW |
4 |
142,858,674 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9518:Prdm2
|
UTSW |
4 |
142,860,579 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9546:Prdm2
|
UTSW |
4 |
142,861,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9547:Prdm2
|
UTSW |
4 |
142,861,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9680:Prdm2
|
UTSW |
4 |
142,859,079 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9730:Prdm2
|
UTSW |
4 |
142,858,659 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
X0017:Prdm2
|
UTSW |
4 |
142,861,277 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCTCAGAGGCAGACTTAAGG -3'
(R):5'- ATGTCTATGTACCAAGCACAGAGC -3'
Sequencing Primer
(F):5'- CTCAGAGGCAGACTTAAGGAACAC -3'
(R):5'- CACAGAGCCCGAGGAGGAC -3'
|
| Posted On |
2022-04-18 |
Incidental Mutation