Incidental Mutation 'R9352:Adamtsl3'
| ID |
708132 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamtsl3
|
| Ensembl Gene |
ENSMUSG00000070469 |
| Gene Name |
ADAMTS-like 3 |
| Synonyms |
9230119C12Rik, punctin-2 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9352 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
81984902-82263658 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 82091656 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Leucine
at position 123
(Q123L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133637
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000173287]
[ENSMUST00000173828]
|
| AlphaFold |
G3UXC7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000173287
AA Change: Q123L
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000133637
Gene: ENSMUSG00000070469
AA Change: Q123L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
38 |
N/A |
INTRINSIC |
|
TSP1
|
90 |
136 |
6.43e-8 |
SMART |
|
TSP1
|
355 |
414 |
1.59e-1 |
SMART |
|
TSP1
|
433 |
492 |
3.72e-4 |
SMART |
|
TSP1
|
494 |
547 |
4.28e-4 |
SMART |
|
TSP1
|
579 |
638 |
1.85e-2 |
SMART |
|
TSP1
|
660 |
717 |
1.75e-2 |
SMART |
|
TSP1
|
719 |
773 |
3.45e-8 |
SMART |
|
TSP1
|
775 |
833 |
3.67e-3 |
SMART |
|
TSP1
|
836 |
894 |
8.99e-2 |
SMART |
|
IGc2
|
938 |
1002 |
7.59e-4 |
SMART |
|
IG
|
1213 |
1296 |
4.87e0 |
SMART |
|
IGc2
|
1326 |
1388 |
1.01e-13 |
SMART |
|
TSP1
|
1441 |
1498 |
1.95e-2 |
SMART |
|
TSP1
|
1500 |
1559 |
6.76e-2 |
SMART |
|
TSP1
|
1616 |
1666 |
3.84e-1 |
SMART |
|
Pfam:PLAC
|
1674 |
1704 |
2.4e-11 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173828
|
| SMART Domains |
Protein: ENSMUSP00000133337
Gene: ENSMUSG00000070469
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
Blast:IG
|
22 |
79 |
1e-26 |
BLAST |
|
SCOP:d1biha4
|
27 |
77 |
2e-5 |
SMART |
|
IG
|
283 |
366 |
4.87e0 |
SMART |
|
IGc2
|
396 |
458 |
1.01e-13 |
SMART |
|
TSP1
|
511 |
568 |
1.95e-2 |
SMART |
|
TSP1
|
570 |
629 |
6.76e-2 |
SMART |
|
TSP1
|
686 |
736 |
3.84e-1 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(10) : Targeted(7) Gene trapped(2) Spontaneous(1)
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adarb2 |
T |
A |
13: 8,807,428 (GRCm39) |
L743Q |
probably damaging |
Het |
| Alpk2 |
C |
A |
18: 65,439,783 (GRCm39) |
D537Y |
probably benign |
Het |
| Anxa4 |
C |
T |
6: 86,742,775 (GRCm39) |
|
probably benign |
Het |
| Arfgap3 |
T |
A |
15: 83,191,127 (GRCm39) |
I464L |
possibly damaging |
Het |
| Asb2 |
C |
T |
12: 103,296,698 (GRCm39) |
V320I |
probably damaging |
Het |
| Axl |
T |
C |
7: 25,462,752 (GRCm39) |
T659A |
possibly damaging |
Het |
| Bbof1 |
A |
G |
12: 84,461,394 (GRCm39) |
H139R |
probably benign |
Het |
| Birc6 |
G |
A |
17: 74,965,347 (GRCm39) |
|
probably null |
Het |
| Cdh23 |
G |
A |
10: 60,143,306 (GRCm39) |
A3005V |
possibly damaging |
Het |
| Chil3 |
A |
T |
3: 106,067,787 (GRCm39) |
F126Y |
probably damaging |
Het |
| Chrnb4 |
T |
A |
9: 54,951,167 (GRCm39) |
D32V |
probably benign |
Het |
| Chst15 |
C |
A |
7: 131,872,257 (GRCm39) |
C8F |
probably damaging |
Het |
| Cntnap5c |
A |
G |
17: 58,399,463 (GRCm39) |
I439V |
probably benign |
Het |
| Crisp2 |
T |
A |
17: 41,078,200 (GRCm39) |
N194I |
probably damaging |
Het |
| Csrnp1 |
G |
A |
9: 119,801,997 (GRCm39) |
T354M |
probably benign |
Het |
| Cul1 |
T |
A |
6: 47,479,426 (GRCm39) |
S231T |
probably benign |
Het |
| Cyp27a1 |
C |
T |
1: 74,752,920 (GRCm39) |
T44M |
possibly damaging |
Het |
| Dgkg |
T |
C |
16: 22,398,581 (GRCm39) |
D232G |
probably damaging |
Het |
| Dnah1 |
G |
T |
14: 31,038,620 (GRCm39) |
Q154K |
probably benign |
Het |
| Dnmt1 |
A |
G |
9: 20,840,384 (GRCm39) |
V304A |
probably benign |
Het |
| Dok6 |
T |
C |
18: 89,492,133 (GRCm39) |
N148S |
probably benign |
Het |
| Fnta |
A |
T |
8: 26,501,119 (GRCm39) |
W134R |
probably damaging |
Het |
| Garin5b |
T |
A |
7: 4,761,605 (GRCm39) |
Y369F |
|
Het |
| Gm32742 |
T |
G |
9: 51,052,544 (GRCm39) |
Q1441P |
possibly damaging |
Het |
| Gm3486 |
T |
C |
14: 41,208,318 (GRCm39) |
Q131R |
possibly damaging |
Het |
| Gnptab |
A |
G |
10: 88,268,350 (GRCm39) |
N486D |
probably benign |
Het |
| H2-Q4 |
T |
G |
17: 35,601,909 (GRCm39) |
F257C |
probably damaging |
Het |
| Hfe |
A |
G |
13: 23,890,119 (GRCm39) |
V218A |
probably benign |
Het |
| Htr2b |
A |
G |
1: 86,027,294 (GRCm39) |
V404A |
probably benign |
Het |
| Hyou1 |
T |
A |
9: 44,300,926 (GRCm39) |
|
probably null |
Het |
| Ikbkb |
T |
C |
8: 23,150,444 (GRCm39) |
D746G |
probably benign |
Het |
| Ikzf4 |
T |
C |
10: 128,472,623 (GRCm39) |
N251S |
probably benign |
Het |
| Il23r |
A |
C |
6: 67,403,592 (GRCm39) |
N436K |
probably damaging |
Het |
| Impg2 |
A |
T |
16: 56,072,470 (GRCm39) |
I301L |
probably benign |
Het |
| Irf4 |
A |
T |
13: 30,936,706 (GRCm39) |
M146L |
probably benign |
Het |
| Iws1 |
G |
A |
18: 32,213,213 (GRCm39) |
E214K |
possibly damaging |
Het |
| Kctd3 |
T |
C |
1: 188,704,777 (GRCm39) |
S665G |
probably damaging |
Het |
| Kiz |
T |
C |
2: 146,794,927 (GRCm39) |
S596P |
probably damaging |
Het |
| Kpna2 |
T |
C |
11: 106,880,292 (GRCm39) |
E452G |
probably damaging |
Het |
| Lclat1 |
A |
G |
17: 73,468,937 (GRCm39) |
Y39C |
probably damaging |
Het |
| Lig3 |
A |
G |
11: 82,686,971 (GRCm39) |
S705G |
probably benign |
Het |
| Lrp1b |
T |
C |
2: 40,748,438 (GRCm39) |
D3134G |
|
Het |
| Map3k8 |
C |
T |
18: 4,349,170 (GRCm39) |
M49I |
probably benign |
Het |
| Mep1b |
A |
G |
18: 21,209,431 (GRCm39) |
D54G |
probably damaging |
Het |
| Mgat5b |
T |
A |
11: 116,857,533 (GRCm39) |
S342R |
probably benign |
Het |
| Mthfd2l |
G |
T |
5: 91,109,172 (GRCm39) |
V201L |
possibly damaging |
Het |
| Naip6 |
G |
T |
13: 100,437,893 (GRCm39) |
T371K |
possibly damaging |
Het |
| Naxd |
T |
C |
8: 11,555,504 (GRCm39) |
I104T |
probably damaging |
Het |
| Nbeal2 |
T |
A |
9: 110,456,916 (GRCm39) |
I2361F |
probably benign |
Het |
| Ogfr |
GGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGG |
GGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGG |
2: 180,237,059 (GRCm39) |
|
probably benign |
Het |
| Or1e17 |
A |
G |
11: 73,831,470 (GRCm39) |
T133A |
probably benign |
Het |
| Or6c75 |
A |
T |
10: 129,337,364 (GRCm39) |
M196L |
probably benign |
Het |
| Or8b8 |
A |
G |
9: 37,808,712 (GRCm39) |
E4G |
probably benign |
Het |
| Or8c16 |
T |
G |
9: 38,130,683 (GRCm39) |
L185R |
probably damaging |
Het |
| Pga5 |
C |
T |
19: 10,646,897 (GRCm39) |
G303S |
probably damaging |
Het |
| Polq |
T |
C |
16: 36,862,252 (GRCm39) |
F591L |
probably damaging |
Het |
| Ppp2r1a |
A |
T |
17: 21,185,499 (GRCm39) |
|
probably null |
Het |
| Prrc1 |
A |
G |
18: 57,522,317 (GRCm39) |
Y383C |
probably damaging |
Het |
| Ptgfr |
A |
T |
3: 151,541,160 (GRCm39) |
V116D |
probably damaging |
Het |
| Qpctl |
C |
T |
7: 18,878,599 (GRCm39) |
R292Q |
possibly damaging |
Het |
| Rasip1 |
G |
A |
7: 45,278,280 (GRCm39) |
V194M |
possibly damaging |
Het |
| Rbbp4 |
A |
T |
4: 129,211,498 (GRCm39) |
N385K |
probably benign |
Het |
| Rbbp8nl |
A |
G |
2: 179,921,053 (GRCm39) |
S444P |
probably benign |
Het |
| Resf1 |
T |
C |
6: 149,236,180 (GRCm39) |
F1500S |
probably damaging |
Het |
| Sf3a1 |
G |
A |
11: 4,110,494 (GRCm39) |
A3T |
unknown |
Het |
| Slc1a4 |
A |
G |
11: 20,282,025 (GRCm39) |
S150P |
probably damaging |
Het |
| Slc28a2 |
T |
C |
2: 122,281,522 (GRCm39) |
|
probably null |
Het |
| Slc30a5 |
A |
G |
13: 100,940,380 (GRCm39) |
I702T |
probably benign |
Het |
| Slc36a4 |
T |
A |
9: 15,633,319 (GRCm39) |
|
probably null |
Het |
| Slf2 |
A |
G |
19: 44,931,957 (GRCm39) |
R671G |
probably null |
Het |
| Smarcc1 |
A |
G |
9: 110,035,220 (GRCm39) |
K881R |
probably null |
Het |
| Srsf11 |
A |
G |
3: 157,717,836 (GRCm39) |
V414A |
unknown |
Het |
| Tcn2 |
T |
C |
11: 3,873,446 (GRCm39) |
N300S |
probably damaging |
Het |
| Tecta |
T |
C |
9: 42,249,147 (GRCm39) |
K1905R |
probably damaging |
Het |
| Tex30 |
T |
G |
1: 44,130,753 (GRCm39) |
|
probably null |
Het |
| Tktl2 |
A |
T |
8: 66,965,974 (GRCm39) |
I511F |
possibly damaging |
Het |
| Tpp1 |
G |
T |
7: 105,398,881 (GRCm39) |
Q183K |
probably benign |
Het |
| Trib2 |
A |
C |
12: 15,865,413 (GRCm39) |
I30R |
probably benign |
Het |
| Tti1 |
A |
G |
2: 157,842,692 (GRCm39) |
L779P |
probably benign |
Het |
| Unc13b |
CGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGC |
CGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGC |
4: 43,177,312 (GRCm39) |
|
probably benign |
Het |
| Unc13b |
GAGCCA |
GAGCCATAGCCA |
4: 43,177,313 (GRCm39) |
|
probably null |
Het |
| Vmn2r112 |
A |
G |
17: 22,822,479 (GRCm39) |
T386A |
probably damaging |
Het |
| Vps16 |
T |
C |
2: 130,283,823 (GRCm39) |
|
probably null |
Het |
| Zan |
T |
G |
5: 137,434,745 (GRCm39) |
N2186T |
unknown |
Het |
| Zdhhc11 |
C |
T |
13: 74,121,800 (GRCm39) |
R104* |
probably null |
Het |
| Zfp318 |
T |
G |
17: 46,721,284 (GRCm39) |
H1176Q |
probably damaging |
Het |
| Zfp335 |
G |
A |
2: 164,742,242 (GRCm39) |
H581Y |
probably damaging |
Het |
| Zfp7 |
T |
C |
15: 76,775,674 (GRCm39) |
I572T |
probably damaging |
Het |
| Zfp955a |
T |
C |
17: 33,461,335 (GRCm39) |
T266A |
probably benign |
Het |
|
| Other mutations in Adamtsl3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01549:Adamtsl3
|
APN |
7 |
82,261,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01936:Adamtsl3
|
APN |
7 |
82,244,579 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02819:Adamtsl3
|
APN |
7 |
82,223,329 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P0012:Adamtsl3
|
UTSW |
7 |
82,223,465 (GRCm39) |
missense |
probably benign |
0.27 |
|
R0096:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0096:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0180:Adamtsl3
|
UTSW |
7 |
82,225,198 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0270:Adamtsl3
|
UTSW |
7 |
82,206,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0295:Adamtsl3
|
UTSW |
7 |
82,197,213 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0329:Adamtsl3
|
UTSW |
7 |
82,171,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0330:Adamtsl3
|
UTSW |
7 |
82,171,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0548:Adamtsl3
|
UTSW |
7 |
82,178,191 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0611:Adamtsl3
|
UTSW |
7 |
82,178,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0671:Adamtsl3
|
UTSW |
7 |
82,172,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0711:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0845:Adamtsl3
|
UTSW |
7 |
82,225,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1119:Adamtsl3
|
UTSW |
7 |
82,189,525 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1458:Adamtsl3
|
UTSW |
7 |
82,172,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1644:Adamtsl3
|
UTSW |
7 |
82,099,298 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1691:Adamtsl3
|
UTSW |
7 |
82,148,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1838:Adamtsl3
|
UTSW |
7 |
82,142,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Adamtsl3
|
UTSW |
7 |
82,227,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2245:Adamtsl3
|
UTSW |
7 |
82,099,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2274:Adamtsl3
|
UTSW |
7 |
82,255,766 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2275:Adamtsl3
|
UTSW |
7 |
82,255,766 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2448:Adamtsl3
|
UTSW |
7 |
82,148,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3725:Adamtsl3
|
UTSW |
7 |
82,261,612 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R3757:Adamtsl3
|
UTSW |
7 |
81,986,415 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3821:Adamtsl3
|
UTSW |
7 |
82,255,687 (GRCm39) |
splice site |
probably benign |
|
|
R4618:Adamtsl3
|
UTSW |
7 |
82,255,728 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4842:Adamtsl3
|
UTSW |
7 |
82,178,069 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4887:Adamtsl3
|
UTSW |
7 |
82,223,822 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4888:Adamtsl3
|
UTSW |
7 |
82,223,822 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4925:Adamtsl3
|
UTSW |
7 |
82,251,507 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4960:Adamtsl3
|
UTSW |
7 |
82,216,185 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5026:Adamtsl3
|
UTSW |
7 |
82,225,262 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5152:Adamtsl3
|
UTSW |
7 |
82,223,752 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5198:Adamtsl3
|
UTSW |
7 |
82,261,006 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5244:Adamtsl3
|
UTSW |
7 |
82,247,277 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5281:Adamtsl3
|
UTSW |
7 |
82,178,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5323:Adamtsl3
|
UTSW |
7 |
82,206,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5523:Adamtsl3
|
UTSW |
7 |
82,223,650 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5602:Adamtsl3
|
UTSW |
7 |
82,206,447 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5638:Adamtsl3
|
UTSW |
7 |
82,260,958 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5682:Adamtsl3
|
UTSW |
7 |
82,255,758 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5782:Adamtsl3
|
UTSW |
7 |
82,189,494 (GRCm39) |
splice site |
probably null |
|
|
R5946:Adamtsl3
|
UTSW |
7 |
82,225,265 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6091:Adamtsl3
|
UTSW |
7 |
82,114,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6258:Adamtsl3
|
UTSW |
7 |
82,178,191 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6500:Adamtsl3
|
UTSW |
7 |
82,227,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6765:Adamtsl3
|
UTSW |
7 |
82,216,232 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6785:Adamtsl3
|
UTSW |
7 |
82,171,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6982:Adamtsl3
|
UTSW |
7 |
82,164,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R7341:Adamtsl3
|
UTSW |
7 |
82,206,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7402:Adamtsl3
|
UTSW |
7 |
82,227,825 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7506:Adamtsl3
|
UTSW |
7 |
82,164,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7549:Adamtsl3
|
UTSW |
7 |
82,223,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7575:Adamtsl3
|
UTSW |
7 |
82,223,756 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7592:Adamtsl3
|
UTSW |
7 |
81,986,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7617:Adamtsl3
|
UTSW |
7 |
82,206,054 (GRCm39) |
splice site |
probably null |
|
|
R7654:Adamtsl3
|
UTSW |
7 |
82,223,702 (GRCm39) |
missense |
probably benign |
|
|
R7721:Adamtsl3
|
UTSW |
7 |
82,255,728 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R7784:Adamtsl3
|
UTSW |
7 |
82,223,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7858:Adamtsl3
|
UTSW |
7 |
82,099,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8109:Adamtsl3
|
UTSW |
7 |
82,251,487 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8125:Adamtsl3
|
UTSW |
7 |
82,099,541 (GRCm39) |
splice site |
probably null |
|
|
R8211:Adamtsl3
|
UTSW |
7 |
82,172,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8348:Adamtsl3
|
UTSW |
7 |
82,253,007 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8360:Adamtsl3
|
UTSW |
7 |
82,197,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8448:Adamtsl3
|
UTSW |
7 |
82,253,007 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8465:Adamtsl3
|
UTSW |
7 |
82,247,330 (GRCm39) |
missense |
probably benign |
0.43 |
|
R8547:Adamtsl3
|
UTSW |
7 |
82,077,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8551:Adamtsl3
|
UTSW |
7 |
82,189,678 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8558:Adamtsl3
|
UTSW |
7 |
82,077,600 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8709:Adamtsl3
|
UTSW |
7 |
82,077,642 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8722:Adamtsl3
|
UTSW |
7 |
82,244,745 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8930:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R8932:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R9131:Adamtsl3
|
UTSW |
7 |
82,244,722 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9169:Adamtsl3
|
UTSW |
7 |
82,223,188 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9272:Adamtsl3
|
UTSW |
7 |
82,189,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9276:Adamtsl3
|
UTSW |
7 |
82,206,710 (GRCm39) |
intron |
probably benign |
|
|
R9351:Adamtsl3
|
UTSW |
7 |
82,169,929 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9749:Adamtsl3
|
UTSW |
7 |
82,099,394 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9750:Adamtsl3
|
UTSW |
7 |
82,244,589 (GRCm39) |
missense |
probably benign |
0.11 |
|
RF005:Adamtsl3
|
UTSW |
7 |
82,261,603 (GRCm39) |
missense |
|
|
|
X0003:Adamtsl3
|
UTSW |
7 |
82,260,967 (GRCm39) |
nonsense |
probably null |
|
|
X0063:Adamtsl3
|
UTSW |
7 |
82,223,365 (GRCm39) |
missense |
probably benign |
0.25 |
|
Z1088:Adamtsl3
|
UTSW |
7 |
82,189,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Adamtsl3
|
UTSW |
7 |
82,148,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCCTGGATTTATGGATGCCTTC -3'
(R):5'- GTGAGTGGACGCATAGTGAC -3'
Sequencing Primer
(F):5'- CCTGGATTTATGGATGCCTTCTTGAG -3'
(R):5'- GAGTGGACGCATAGTGACATATTTAC -3'
|
| Posted On |
2022-04-18 |
Incidental Mutation