Incidental Mutation 'R9355:Clasp2'
| ID |
708354 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clasp2
|
| Ensembl Gene |
ENSMUSG00000033392 |
| Gene Name |
CLIP associating protein 2 |
| Synonyms |
CLASP2alpha, 1500004F14Rik, CLASP2gamma, CLASP2, CLASP2beta, 8030404L10Rik |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9355 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
113570541-113748750 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 113664309 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Aspartic acid
at position 310
(V310D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000150741
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000111838]
[ENSMUST00000163895]
[ENSMUST00000166734]
[ENSMUST00000213663]
[ENSMUST00000214522]
[ENSMUST00000215022]
[ENSMUST00000216817]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000111838
AA Change: V83D
PolyPhen 2
Score 0.936 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000107469
Gene: ENSMUSG00000033392
AA Change: V83D
| Domain | Start | End | E-Value | Type |
|---|
|
TOG
|
90 |
323 |
1.17e-8 |
SMART |
|
low complexity region
|
382 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
459 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
473 |
484 |
N/A |
INTRINSIC |
|
low complexity region
|
562 |
572 |
N/A |
INTRINSIC |
|
low complexity region
|
614 |
634 |
N/A |
INTRINSIC |
|
TOG
|
640 |
877 |
2.03e-1 |
SMART |
|
low complexity region
|
995 |
1009 |
N/A |
INTRINSIC |
|
TOG
|
1043 |
1274 |
1.49e-24 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000163895
AA Change: V83D
PolyPhen 2
Score 0.937 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000128460
Gene: ENSMUSG00000033392
AA Change: V83D
| Domain | Start | End | E-Value | Type |
|---|
|
TOG
|
90 |
323 |
1.17e-8 |
SMART |
|
low complexity region
|
382 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
459 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
473 |
484 |
N/A |
INTRINSIC |
|
low complexity region
|
583 |
593 |
N/A |
INTRINSIC |
|
low complexity region
|
635 |
655 |
N/A |
INTRINSIC |
|
TOG
|
661 |
898 |
2.03e-1 |
SMART |
|
low complexity region
|
1016 |
1030 |
N/A |
INTRINSIC |
|
TOG
|
1064 |
1295 |
1.49e-24 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000166734
AA Change: V83D
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000130201
Gene: ENSMUSG00000033392
AA Change: V83D
| Domain | Start | End | E-Value | Type |
|---|
|
TOG
|
90 |
323 |
1.17e-8 |
SMART |
|
low complexity region
|
382 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
459 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
473 |
484 |
N/A |
INTRINSIC |
|
low complexity region
|
562 |
572 |
N/A |
INTRINSIC |
|
low complexity region
|
614 |
634 |
N/A |
INTRINSIC |
|
TOG
|
640 |
878 |
7.51e-1 |
SMART |
|
low complexity region
|
996 |
1010 |
N/A |
INTRINSIC |
|
TOG
|
1044 |
1275 |
1.49e-24 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000213663
AA Change: V310D
PolyPhen 2
Score 0.322 (Sensitivity: 0.90; Specificity: 0.89)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000214522
AA Change: V83D
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000215022
AA Change: V83D
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000216817
AA Change: V310D
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Targeted deletion of this gene leads to impaired formation of stable microtubules in a wound healing assay, and results in a 2-fold reduction of directionally persistent migration in mutant embryonic fibroblasts. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ano9 |
A |
G |
7: 140,681,817 (GRCm39) |
V747A |
probably benign |
Het |
| Arfgef1 |
G |
A |
1: 10,270,000 (GRCm39) |
P383L |
probably benign |
Het |
| Arhgef4 |
A |
G |
1: 34,849,630 (GRCm39) |
E407G |
probably benign |
Het |
| Astn1 |
C |
T |
1: 158,511,721 (GRCm39) |
L1188F |
probably damaging |
Het |
| Atg2b |
G |
A |
12: 105,636,980 (GRCm39) |
P179S |
possibly damaging |
Het |
| Bcl9l |
G |
A |
9: 44,419,000 (GRCm39) |
R983H |
probably benign |
Het |
| Bmp2k |
T |
A |
5: 97,211,366 (GRCm39) |
Y511* |
probably null |
Het |
| C1galt1 |
G |
T |
6: 7,866,474 (GRCm39) |
V107F |
probably damaging |
Het |
| Car3 |
T |
A |
3: 14,928,664 (GRCm39) |
N11K |
|
Het |
| Ccdc170 |
A |
G |
10: 4,508,695 (GRCm39) |
R640G |
probably benign |
Het |
| Cep126 |
A |
G |
9: 8,100,038 (GRCm39) |
V832A |
possibly damaging |
Het |
| Ces1h |
C |
T |
8: 94,101,149 (GRCm39) |
V49I |
|
Het |
| Comp |
C |
T |
8: 70,828,699 (GRCm39) |
T177M |
probably benign |
Het |
| Coro1c |
T |
C |
5: 114,003,726 (GRCm39) |
S98G |
probably damaging |
Het |
| Cpa6 |
C |
T |
1: 10,479,520 (GRCm39) |
V238I |
probably benign |
Het |
| Crebrf |
T |
C |
17: 26,962,094 (GRCm39) |
F397S |
probably damaging |
Het |
| Dcpp1 |
C |
A |
17: 24,099,987 (GRCm39) |
Q3K |
possibly damaging |
Het |
| Dzip1l |
A |
G |
9: 99,543,144 (GRCm39) |
D533G |
possibly damaging |
Het |
| Ecpas |
A |
T |
4: 58,844,114 (GRCm39) |
S551T |
probably benign |
Het |
| Epha5 |
T |
C |
5: 84,253,890 (GRCm39) |
E524G |
probably damaging |
Het |
| Epha7 |
A |
G |
4: 28,935,806 (GRCm39) |
Y476C |
probably damaging |
Het |
| Erich5 |
G |
T |
15: 34,471,001 (GRCm39) |
V77F |
probably damaging |
Het |
| Fat4 |
A |
G |
3: 39,036,047 (GRCm39) |
Y3233C |
probably damaging |
Het |
| Ggt1 |
T |
A |
10: 75,421,716 (GRCm39) |
V521E |
probably benign |
Het |
| Gm5431 |
A |
G |
11: 48,785,275 (GRCm39) |
Y89H |
probably damaging |
Het |
| Gm5624 |
A |
T |
14: 44,799,272 (GRCm39) |
L95* |
probably null |
Het |
| Gphn |
A |
G |
12: 78,538,968 (GRCm39) |
T205A |
probably damaging |
Het |
| Grik5 |
C |
A |
7: 24,767,597 (GRCm39) |
A28S |
possibly damaging |
Het |
| H2-K2 |
A |
G |
17: 34,216,120 (GRCm39) |
S300P |
probably benign |
Het |
| H2-Oa |
T |
C |
17: 34,313,723 (GRCm39) |
L227P |
possibly damaging |
Het |
| Hhip |
T |
C |
8: 80,778,233 (GRCm39) |
N99S |
probably damaging |
Het |
| Hmcn2 |
A |
T |
2: 31,328,302 (GRCm39) |
M4328L |
probably benign |
Het |
| Htt |
A |
T |
5: 35,053,247 (GRCm39) |
M2527L |
probably benign |
Het |
| Impdh2 |
A |
T |
9: 108,442,402 (GRCm39) |
H466L |
probably benign |
Het |
| Itgae |
G |
A |
11: 73,006,906 (GRCm39) |
G384D |
probably damaging |
Het |
| Krt90 |
T |
C |
15: 101,461,714 (GRCm39) |
S496G |
unknown |
Het |
| Krtap5-5 |
A |
G |
7: 141,783,114 (GRCm39) |
S179P |
unknown |
Het |
| Lif |
C |
T |
11: 4,219,044 (GRCm39) |
R63W |
probably damaging |
Het |
| Lrrc10 |
T |
C |
10: 116,881,881 (GRCm39) |
V185A |
probably damaging |
Het |
| Lrrc27 |
A |
C |
7: 138,822,648 (GRCm39) |
Q513P |
probably damaging |
Het |
| Ltbp2 |
G |
A |
12: 84,837,864 (GRCm39) |
P1192L |
probably benign |
Het |
| Map2k3 |
T |
C |
11: 60,823,055 (GRCm39) |
S3P |
possibly damaging |
Het |
| Mc2r |
T |
C |
18: 68,541,195 (GRCm39) |
T33A |
probably benign |
Het |
| Mefv |
T |
A |
16: 3,525,882 (GRCm39) |
D795V |
probably damaging |
Het |
| Megf6 |
A |
T |
4: 154,338,282 (GRCm39) |
R451W |
probably damaging |
Het |
| Mrpl21 |
G |
A |
19: 3,336,937 (GRCm39) |
V103M |
probably damaging |
Het |
| Mtmr14 |
GCCGCCGCCTCGGCGGGTTCCACCGCCTCGTCGGGCAGCCCGCCGCCTC |
GCCGCCGCCTC |
6: 113,214,948 (GRCm39) |
|
probably null |
Het |
| Myom1 |
T |
C |
17: 71,384,888 (GRCm39) |
S760P |
probably damaging |
Het |
| Ndst4 |
A |
G |
3: 125,403,246 (GRCm39) |
Y451C |
probably damaging |
Het |
| Nkain4 |
T |
C |
2: 180,577,775 (GRCm39) |
N193S |
possibly damaging |
Het |
| Opa1 |
T |
A |
16: 29,432,807 (GRCm39) |
L490H |
probably damaging |
Het |
| Opcml |
A |
C |
9: 28,814,650 (GRCm39) |
I301L |
probably benign |
Het |
| Or10ak16 |
G |
A |
4: 118,750,784 (GRCm39) |
S168N |
probably benign |
Het |
| Or1e33 |
A |
G |
11: 73,738,643 (GRCm39) |
F103L |
probably damaging |
Het |
| Or4p23 |
A |
T |
2: 88,576,749 (GRCm39) |
I161N |
probably damaging |
Het |
| Or52s19 |
T |
C |
7: 103,008,125 (GRCm39) |
H92R |
probably benign |
Het |
| Pabpc1l |
T |
C |
2: 163,884,469 (GRCm39) |
L402P |
probably benign |
Het |
| Palld |
C |
T |
8: 61,969,691 (GRCm39) |
R1211H |
unknown |
Het |
| Peak1 |
G |
T |
9: 56,167,454 (GRCm39) |
A158E |
probably damaging |
Het |
| Ppfibp2 |
C |
T |
7: 107,322,169 (GRCm39) |
P406L |
probably benign |
Het |
| Qpctl |
T |
C |
7: 18,875,146 (GRCm39) |
H362R |
probably damaging |
Het |
| Ripor2 |
A |
G |
13: 24,885,694 (GRCm39) |
H643R |
probably benign |
Het |
| Scn11a |
A |
T |
9: 119,584,160 (GRCm39) |
L1485Q |
probably damaging |
Het |
| Scn2a |
A |
T |
2: 65,594,433 (GRCm39) |
I1761F |
probably damaging |
Het |
| Scrn3 |
A |
G |
2: 73,166,077 (GRCm39) |
D370G |
probably benign |
Het |
| Sec24b |
A |
T |
3: 129,787,489 (GRCm39) |
F877Y |
possibly damaging |
Het |
| Slc35f3 |
T |
C |
8: 127,108,967 (GRCm39) |
I172T |
probably damaging |
Het |
| Smc3 |
T |
C |
19: 53,622,544 (GRCm39) |
|
probably null |
Het |
| Smpd3 |
C |
T |
8: 106,991,825 (GRCm39) |
V243M |
probably damaging |
Het |
| Sos1 |
T |
A |
17: 80,722,479 (GRCm39) |
I856F |
possibly damaging |
Het |
| Sp2 |
A |
T |
11: 96,852,231 (GRCm39) |
L231H |
possibly damaging |
Het |
| Syne1 |
T |
C |
10: 5,318,255 (GRCm39) |
Y457C |
probably damaging |
Het |
| Tdpoz6 |
T |
C |
3: 93,600,307 (GRCm39) |
T21A |
possibly damaging |
Het |
| Tekt5 |
T |
C |
16: 10,213,268 (GRCm39) |
T6A |
possibly damaging |
Het |
| Tln2 |
G |
T |
9: 67,262,529 (GRCm39) |
T574K |
possibly damaging |
Het |
| Tmem161a |
T |
C |
8: 70,633,821 (GRCm39) |
S313P |
probably damaging |
Het |
| Trmt12 |
G |
A |
15: 58,744,824 (GRCm39) |
C74Y |
probably damaging |
Het |
| Trpc6 |
A |
G |
9: 8,649,473 (GRCm39) |
D561G |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,700,769 (GRCm39) |
V62A |
|
Het |
| Tubgcp5 |
T |
C |
7: 55,467,177 (GRCm39) |
|
probably null |
Het |
| Unc13a |
C |
T |
8: 72,098,375 (GRCm39) |
V1137M |
possibly damaging |
Het |
| Zfp729a |
A |
G |
13: 67,767,515 (GRCm39) |
C905R |
probably damaging |
Het |
| Zfp735 |
A |
G |
11: 73,602,362 (GRCm39) |
I435M |
probably benign |
Het |
| Zswim4 |
C |
A |
8: 84,955,687 (GRCm39) |
G271W |
probably damaging |
Het |
|
| Other mutations in Clasp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00772:Clasp2
|
APN |
9 |
113,735,060 (GRCm39) |
splice site |
probably benign |
|
|
IGL00885:Clasp2
|
APN |
9 |
113,740,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01314:Clasp2
|
APN |
9 |
113,735,195 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL01344:Clasp2
|
APN |
9 |
113,642,360 (GRCm39) |
splice site |
probably null |
|
|
IGL01567:Clasp2
|
APN |
9 |
113,709,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02238:Clasp2
|
APN |
9 |
113,709,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02299:Clasp2
|
APN |
9 |
113,709,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02323:Clasp2
|
APN |
9 |
113,697,794 (GRCm39) |
splice site |
probably benign |
|
|
IGL02635:Clasp2
|
APN |
9 |
113,737,910 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02645:Clasp2
|
APN |
9 |
113,719,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02976:Clasp2
|
APN |
9 |
113,735,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03190:Clasp2
|
APN |
9 |
113,673,208 (GRCm39) |
nonsense |
probably null |
|
|
IGL03219:Clasp2
|
APN |
9 |
113,677,545 (GRCm39) |
splice site |
probably benign |
|
|
PIT4810001:Clasp2
|
UTSW |
9 |
113,735,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0067:Clasp2
|
UTSW |
9 |
113,689,209 (GRCm39) |
splice site |
probably benign |
|
|
R0067:Clasp2
|
UTSW |
9 |
113,689,209 (GRCm39) |
splice site |
probably benign |
|
|
R0421:Clasp2
|
UTSW |
9 |
113,683,370 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0432:Clasp2
|
UTSW |
9 |
113,738,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0458:Clasp2
|
UTSW |
9 |
113,735,292 (GRCm39) |
splice site |
probably null |
|
|
R0865:Clasp2
|
UTSW |
9 |
113,740,568 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R0972:Clasp2
|
UTSW |
9 |
113,676,773 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1037:Clasp2
|
UTSW |
9 |
113,725,702 (GRCm39) |
splice site |
probably benign |
|
|
R1925:Clasp2
|
UTSW |
9 |
113,735,265 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2015:Clasp2
|
UTSW |
9 |
113,740,568 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R2066:Clasp2
|
UTSW |
9 |
113,735,225 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R2330:Clasp2
|
UTSW |
9 |
113,705,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2568:Clasp2
|
UTSW |
9 |
113,707,832 (GRCm39) |
missense |
probably benign |
|
|
R3011:Clasp2
|
UTSW |
9 |
113,730,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3879:Clasp2
|
UTSW |
9 |
113,719,029 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3915:Clasp2
|
UTSW |
9 |
113,737,805 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3928:Clasp2
|
UTSW |
9 |
113,735,173 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4323:Clasp2
|
UTSW |
9 |
113,719,027 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4571:Clasp2
|
UTSW |
9 |
113,676,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4975:Clasp2
|
UTSW |
9 |
113,732,984 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5445:Clasp2
|
UTSW |
9 |
113,733,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5564:Clasp2
|
UTSW |
9 |
113,641,836 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5697:Clasp2
|
UTSW |
9 |
113,689,190 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5780:Clasp2
|
UTSW |
9 |
113,679,220 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5787:Clasp2
|
UTSW |
9 |
113,691,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6011:Clasp2
|
UTSW |
9 |
113,705,315 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6026:Clasp2
|
UTSW |
9 |
113,740,646 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6090:Clasp2
|
UTSW |
9 |
113,681,803 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6262:Clasp2
|
UTSW |
9 |
113,705,420 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6427:Clasp2
|
UTSW |
9 |
113,721,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6464:Clasp2
|
UTSW |
9 |
113,602,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6586:Clasp2
|
UTSW |
9 |
113,642,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6628:Clasp2
|
UTSW |
9 |
113,725,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6745:Clasp2
|
UTSW |
9 |
113,704,338 (GRCm39) |
nonsense |
probably null |
|
|
R7032:Clasp2
|
UTSW |
9 |
113,683,391 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7165:Clasp2
|
UTSW |
9 |
113,615,467 (GRCm39) |
splice site |
probably null |
|
|
R7221:Clasp2
|
UTSW |
9 |
113,681,825 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7336:Clasp2
|
UTSW |
9 |
113,705,421 (GRCm39) |
splice site |
probably null |
|
|
R7583:Clasp2
|
UTSW |
9 |
113,737,755 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7774:Clasp2
|
UTSW |
9 |
113,677,804 (GRCm39) |
splice site |
probably null |
|
|
R7895:Clasp2
|
UTSW |
9 |
113,733,016 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8084:Clasp2
|
UTSW |
9 |
113,676,823 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8109:Clasp2
|
UTSW |
9 |
113,740,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Clasp2
|
UTSW |
9 |
113,732,974 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8230:Clasp2
|
UTSW |
9 |
113,721,482 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8810:Clasp2
|
UTSW |
9 |
113,728,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8879:Clasp2
|
UTSW |
9 |
113,602,773 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8888:Clasp2
|
UTSW |
9 |
113,732,936 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R8889:Clasp2
|
UTSW |
9 |
113,709,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8892:Clasp2
|
UTSW |
9 |
113,709,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8922:Clasp2
|
UTSW |
9 |
113,725,728 (GRCm39) |
nonsense |
probably null |
|
|
R9042:Clasp2
|
UTSW |
9 |
113,735,065 (GRCm39) |
missense |
probably benign |
|
|
R9195:Clasp2
|
UTSW |
9 |
113,671,045 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9481:Clasp2
|
UTSW |
9 |
113,670,669 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9502:Clasp2
|
UTSW |
9 |
113,737,866 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9523:Clasp2
|
UTSW |
9 |
113,705,372 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9525:Clasp2
|
UTSW |
9 |
113,740,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9653:Clasp2
|
UTSW |
9 |
113,670,993 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9699:Clasp2
|
UTSW |
9 |
113,738,614 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9738:Clasp2
|
UTSW |
9 |
113,590,665 (GRCm39) |
nonsense |
probably null |
|
|
R9775:Clasp2
|
UTSW |
9 |
113,725,740 (GRCm39) |
missense |
probably benign |
|
|
X0022:Clasp2
|
UTSW |
9 |
113,681,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Clasp2
|
UTSW |
9 |
113,599,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Clasp2
|
UTSW |
9 |
113,737,863 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTCTCTGGAAGTTGCCCTG -3'
(R):5'- TGCCAAGGCTGTAAAGCTCC -3'
Sequencing Primer
(F):5'- CTCTGGAAGTTGCCCTGTTTTAAAAC -3'
(R):5'- TATGTGGAACTCAGGGTCAAACTC -3'
|
| Posted On |
2022-04-18 |
Incidental Mutation