Mutagenetix > Incidental Mutation

Incidental Mutation 'R9358:Naip2'

708548

Institutional Source

Beutler Lab

Gene Symbol

Naip2

Ensembl Gene

ENSMUSG00000078945

Gene Name

NLR family, apoptosis inhibitory protein 2

Synonyms

Birc1b, Naip2, Naip-rs6

MMRRC Submission

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.066) question?

Stock #

R9358 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

100144063-100202092 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 100161572 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Aspartic acid at position 652 (V652D)

Ref Sequence

ENSEMBL: ENSMUSP00000070827 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000067975] [ENSMUST00000117913] [ENSMUST00000167986]

AlphaFold

Q9QUK4

Predicted Effect

probably damaging
Transcript: ENSMUST00000067975
AA Change: V652D

PolyPhen 2 Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000070827
Gene: ENSMUSG00000078945
AA Change: V652D

Domain	Start	End	E-Value	Type
BIR	58	129	7.95e-18	SMART
BIR	157	229	5.31e-37	SMART
BIR	276	347	4.22e-31	SMART
Pfam:NACHT	508	662	1.9e-36	PFAM
low complexity region	954	964	N/A	INTRINSIC
low complexity region	1116	1126	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000117913
AA Change: V652D

PolyPhen 2 Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000113890
Gene: ENSMUSG00000078945
AA Change: V652D

Domain	Start	End	E-Value	Type
BIR	58	129	7.95e-18	SMART
BIR	157	229	5.31e-37	SMART
BIR	276	347	4.22e-31	SMART
Pfam:NACHT	508	662	1.9e-36	PFAM
low complexity region	954	964	N/A	INTRINSIC
low complexity region	1116	1126	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000167986
AA Change: V652D

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000125852
Gene: ENSMUSG00000078945
AA Change: V652D

Domain	Start	End	E-Value	Type
BIR	58	129	7.95e-18	SMART
BIR	157	229	5.31e-37	SMART
BIR	276	347	4.22e-31	SMART
Pfam:NACHT	508	662	8.6e-35	PFAM
low complexity region	954	964	N/A	INTRINSIC
low complexity region	1116	1126	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.6%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016]

Allele List at MGI

Other mutations in this stock

Total: 73 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930432M17Rik	A	T	3: 121,681,327	K149*	probably null	Het
Ap3m2	G	A	8: 22,790,943	S365F	possibly damaging	Het
Apob	T	A	12: 8,010,833	I3105K	probably benign	Het
Arfgef3	A	G	10: 18,616,880	L1261P	probably damaging	Het
Armc8	A	G	9: 99,568,600		probably null	Het
Axin2	A	G	11: 108,924,047	T254A	probably benign	Het
BC005561	T	C	5: 104,519,960	F783L	possibly damaging	Het
C530008M17Rik	A	T	5: 76,854,989	I137F	probably damaging	Het
Cachd1	G	A	4: 100,976,425	V800M	probably damaging	Het
Camta1	A	G	4: 151,138,424	L892P	probably damaging	Het
Cfap58	C	T	19: 47,974,548	R466*	probably null	Het
Cilp	A	G	9: 65,275,987	Q391R	probably benign	Het
Ctcfl	T	A	2: 173,118,788	M1L	possibly damaging	Het
Dnah14	G	A	1: 181,709,033	A2414T	probably benign	Het
Dnah2	A	G	11: 69,515,766	L550P	probably damaging	Het
Erich6b	T	A	14: 75,665,228	S162T	probably benign	Het
Fbxw7	C	A	3: 84,976,254	H578Q		Het
Fer	T	C	17: 63,973,081	L418P	possibly damaging	Het
Fndc3b	A	C	3: 27,451,407	L904R	possibly damaging	Het
Gabrg1	A	T	5: 70,778,079	I249N	possibly damaging	Het
Gbe1	T	A	16: 70,441,239	D304E	probably benign	Het
Gm10549	C	T	18: 33,464,322	P54S	unknown	Het
Gm13212	A	T	4: 145,623,043	Y350F	possibly damaging	Het
Gpatch4	G	T	3: 88,055,145	E222*	probably null	Het
Heatr1	A	T	13: 12,418,206	T1146S	probably benign	Het
Hrc	A	C	7: 45,336,560	E378D	probably benign	Het
Hspg2	G	T	4: 137,517,598	R878L	probably damaging	Het
Igkv1-122	A	G	6: 68,016,772	M11V	probably benign	Het
Itih3	T	A	14: 30,921,928	K75*	probably null	Het
Jag1	A	G	2: 137,083,028	V1218A	probably benign	Het
Kif28	C	T	1: 179,736,130	D94N	probably benign	Het
Lama2	A	G	10: 27,616,765	L11P	unknown	Het
Lama2	G	A	10: 27,188,382	T1201M	possibly damaging	Het
Lrfn2	T	C	17: 49,096,502	V551A	probably damaging	Het
Lrrc8d	A	G	5: 105,812,492	N256S	probably benign	Het
Mindy1	C	T	3: 95,295,279	L394F	probably benign	Het
Mon2	A	G	10: 123,032,547	S534P	probably benign	Het
Mrps5	T	A	2: 127,595,814	I187N	probably benign	Het
Mto1	A	G	9: 78,457,558	M360V	probably benign	Het
Muc16	T	G	9: 18,642,224	I4258L	probably benign	Het
Myo10	A	G	15: 25,781,434	D1005G	possibly damaging	Het
Myo18b	T	A	5: 112,795,403	R1645S	possibly damaging	Het
Naip5	T	A	13: 100,219,830	E1092D	probably benign	Het
Ncapd2	A	T	6: 125,186,143	M134K	probably benign	Het
Nup107	A	G	10: 117,750,963	F893S	probably damaging	Het
Olfr1307	A	G	2: 111,945,084	V124A	probably benign	Het
Olfr218	A	T	1: 173,204,174	R273W	probably damaging	Het
Olfr395	A	T	11: 73,906,625	I289N	probably damaging	Het
Olfr488	C	T	7: 108,255,592	C182Y	probably damaging	Het
Olfr748	A	G	14: 50,710,345	E5G	probably benign	Het
Pcgf1	G	T	6: 83,079,452	R124L	probably benign	Het
Pdcd10	A	T	3: 75,541,226	N10K	probably damaging	Het
Pdx1	C	T	5: 147,270,254	Q6*	probably null	Het
Plcl1	T	C	1: 55,696,651	S384P	probably damaging	Het
Serpina1b	T	A	12: 103,728,394	T364S	possibly damaging	Het
Slc5a11	C	T	7: 123,258,552	T288I	probably damaging	Het
Slc6a1	A	T	6: 114,314,310	S515C	probably damaging	Het
Snca	A	T	6: 60,733,137	D119E	probably benign	Het
Sorcs2	T	C	5: 36,043,470	D578G	probably damaging	Het
Sulf1	T	A	1: 12,820,505	L389Q	probably damaging	Het
Tln1	A	C	4: 43,532,084	I2501S	possibly damaging	Het
Tmem191c	A	G	16: 17,276,393	E27G	probably damaging	Het
Tmem200a	G	T	10: 25,993,779	N197K	probably benign	Het
Tmem207	A	T	16: 26,526,684	S11T	probably benign	Het
Ttn	T	C	2: 76,734,609	T28425A	probably damaging	Het
Ush2a	C	T	1: 188,874,950	T4014M	probably benign	Het
Vac14	G	A	8: 110,712,747		probably null	Het
Vmn2r32	A	T	7: 7,474,198	I398K	probably damaging	Het
Vmn2r77	A	T	7: 86,803,028	H472L	probably benign	Het
Vps45	C	T	3: 96,033,664		probably null	Het
Wdr26	T	C	1: 181,191,858	H334R	probably damaging	Het
Zmynd10	A	G	9: 107,549,050	D132G	possibly damaging	Het
Zpbp2	A	G	11: 98,553,948	T123A	probably benign	Het

Other mutations in Naip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00515:Naip2	APN	13	100,154,887 (GRCm38)	missense	probably benign	0.00
IGL00676:Naip2	APN	13	100,152,632 (GRCm38)	missense	probably damaging	1.00
IGL00870:Naip2	APN	13	100,152,060 (GRCm38)	splice site	probably benign
IGL00908:Naip2	APN	13	100,160,649 (GRCm38)	missense	probably benign	0.01
IGL00916:Naip2	APN	13	100,161,431 (GRCm38)	missense	probably damaging	0.97
IGL00949:Naip2	APN	13	100,161,591 (GRCm38)	missense	probably damaging	1.00
IGL01010:Naip2	APN	13	100,154,938 (GRCm38)	missense	probably damaging	0.99
IGL01642:Naip2	APN	13	100,160,937 (GRCm38)	missense	probably damaging	0.97
IGL01884:Naip2	APN	13	100,188,821 (GRCm38)	splice site	probably benign
IGL01917:Naip2	APN	13	100,162,083 (GRCm38)	missense	probably benign	0.00
IGL02015:Naip2	APN	13	100,161,607 (GRCm38)	missense	possibly damaging	0.57
IGL02315:Naip2	APN	13	100,161,236 (GRCm38)	missense	probably damaging	1.00
IGL02328:Naip2	APN	13	100,161,369 (GRCm38)	missense	probably damaging	1.00
IGL02735:Naip2	APN	13	100,160,214 (GRCm38)	missense	probably damaging	0.99
IGL02738:Naip2	APN	13	100,189,177 (GRCm38)	missense	probably benign	0.01
IGL02887:Naip2	APN	13	100,161,512 (GRCm38)	missense	possibly damaging	0.90
IGL02894:Naip2	APN	13	100,183,789 (GRCm38)	missense	probably benign
IGL02894:Naip2	APN	13	100,160,997 (GRCm38)	missense	probably damaging	1.00
IGL02974:Naip2	APN	13	100,161,678 (GRCm38)	missense	probably damaging	1.00
IGL03024:Naip2	APN	13	100,189,354 (GRCm38)	missense	possibly damaging	0.50
IGL03056:Naip2	APN	13	100,162,287 (GRCm38)	missense	possibly damaging	0.90
IGL03281:Naip2	APN	13	100,161,620 (GRCm38)	missense	probably damaging	0.99
R0131:Naip2	UTSW	13	100,183,788 (GRCm38)	missense	probably benign	0.01
R0131:Naip2	UTSW	13	100,183,788 (GRCm38)	missense	probably benign	0.01
R0132:Naip2	UTSW	13	100,183,788 (GRCm38)	missense	probably benign	0.01
R0310:Naip2	UTSW	13	100,148,842 (GRCm38)	missense	probably damaging	1.00
R0367:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0368:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0422:Naip2	UTSW	13	100,161,113 (GRCm38)	missense	probably benign	0.10
R0441:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0445:Naip2	UTSW	13	100,161,887 (GRCm38)	missense	possibly damaging	0.91
R0446:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0464:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0466:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0467:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0486:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0533:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0853:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R0853:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R0855:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R0855:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R0904:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R0904:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R0906:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R0906:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R0908:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R0908:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R0959:Naip2	UTSW	13	100,154,911 (GRCm38)	missense	probably benign	0.03
R0959:Naip2	UTSW	13	100,154,878 (GRCm38)	missense	probably benign	0.01
R0962:Naip2	UTSW	13	100,179,385 (GRCm38)	missense	probably damaging	1.00
R1024:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1024:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1186:Naip2	UTSW	13	100,162,037 (GRCm38)	frame shift	probably null
R1186:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1217:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1217:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1340:Naip2	UTSW	13	100,189,122 (GRCm38)	missense	possibly damaging	0.80
R1342:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1342:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1404:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1423:Naip2	UTSW	13	100,154,847 (GRCm38)	intron	probably benign
R1423:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1423:Naip2	UTSW	13	100,154,878 (GRCm38)	missense	probably benign	0.01
R1423:Naip2	UTSW	13	100,154,872 (GRCm38)	missense	possibly damaging	0.59
R1426:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1426:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1472:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1575:Naip2	UTSW	13	100,155,029 (GRCm38)	intron	probably benign
R1575:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
R1576:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
R1576:Naip2	UTSW	13	100,155,029 (GRCm38)	intron	probably benign
R1599:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1640:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1641:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1642:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1643:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1644:Naip2	UTSW	13	100,182,929 (GRCm38)	missense	possibly damaging	0.83
R1681:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1681:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1891:Naip2	UTSW	13	100,154,887 (GRCm38)	missense	probably benign	0.00
R1913:Naip2	UTSW	13	100,152,157 (GRCm38)	critical splice acceptor site	probably null
R1937:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1937:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1993:Naip2	UTSW	13	100,162,007 (GRCm38)	missense	probably benign	0.03
R2001:Naip2	UTSW	13	100,144,588 (GRCm38)	missense	probably damaging	1.00
R2055:Naip2	UTSW	13	100,179,372 (GRCm38)	missense	probably benign	0.07
R2198:Naip2	UTSW	13	100,152,592 (GRCm38)	missense	probably damaging	1.00
R2906:Naip2	UTSW	13	100,161,996 (GRCm38)	missense	probably damaging	1.00
R2931:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
R3014:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R3016:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R3037:Naip2	UTSW	13	100,154,949 (GRCm38)	missense	probably benign	0.08
R3414:Naip2	UTSW	13	100,189,263 (GRCm38)	nonsense	probably null
R3437:Naip2	UTSW	13	100,154,911 (GRCm38)	missense	probably benign	0.03
R3713:Naip2	UTSW	13	100,161,902 (GRCm38)	missense	probably damaging	1.00
R3806:Naip2	UTSW	13	100,152,634 (GRCm38)	missense	possibly damaging	0.92
R3847:Naip2	UTSW	13	100,179,432 (GRCm38)	missense	probably damaging	1.00
R3847:Naip2	UTSW	13	100,179,433 (GRCm38)	missense	probably damaging	1.00
R3848:Naip2	UTSW	13	100,179,432 (GRCm38)	missense	probably damaging	1.00
R3848:Naip2	UTSW	13	100,179,433 (GRCm38)	missense	probably damaging	1.00
R3849:Naip2	UTSW	13	100,179,432 (GRCm38)	missense	probably damaging	1.00
R3849:Naip2	UTSW	13	100,179,433 (GRCm38)	missense	probably damaging	1.00
R3850:Naip2	UTSW	13	100,179,432 (GRCm38)	missense	probably damaging	1.00
R3850:Naip2	UTSW	13	100,179,433 (GRCm38)	missense	probably damaging	1.00
R3891:Naip2	UTSW	13	100,161,098 (GRCm38)	missense	probably damaging	0.99
R4419:Naip2	UTSW	13	100,160,625 (GRCm38)	missense	probably benign	0.03
R4456:Naip2	UTSW	13	100,154,911 (GRCm38)	missense	probably benign	0.03
R4458:Naip2	UTSW	13	100,154,911 (GRCm38)	missense	probably benign	0.03
R4689:Naip2	UTSW	13	100,148,812 (GRCm38)	missense	probably damaging	1.00
R4797:Naip2	UTSW	13	100,161,735 (GRCm38)	missense	probably damaging	1.00
R4852:Naip2	UTSW	13	100,161,536 (GRCm38)	missense	probably benign
R4922:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R5135:Naip2	UTSW	13	100,179,440 (GRCm38)	missense	probably damaging	0.98
R5185:Naip2	UTSW	13	100,189,351 (GRCm38)	missense	probably damaging	1.00
R5265:Naip2	UTSW	13	100,152,560 (GRCm38)	missense	probably damaging	1.00
R5451:Naip2	UTSW	13	100,188,860 (GRCm38)	missense	probably benign	0.12
R5521:Naip2	UTSW	13	100,154,914 (GRCm38)	missense	probably damaging	1.00
R5737:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign	0.38
R6244:Naip2	UTSW	13	100,152,137 (GRCm38)	missense	probably damaging	1.00
R6478:Naip2	UTSW	13	100,162,041 (GRCm38)	missense	probably benign
R6480:Naip2	UTSW	13	100,162,041 (GRCm38)	missense	probably benign
R6481:Naip2	UTSW	13	100,162,041 (GRCm38)	missense	probably benign
R6490:Naip2	UTSW	13	100,160,685 (GRCm38)	missense	probably benign
R6653:Naip2	UTSW	13	100,152,136 (GRCm38)	missense	probably benign	0.00
R6653:Naip2	UTSW	13	100,161,844 (GRCm38)	missense	probably benign
R6768:Naip2	UTSW	13	100,178,324 (GRCm38)	nonsense	probably null
R6791:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R6793:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R6890:Naip2	UTSW	13	100,162,041 (GRCm38)	missense	probably benign
R7036:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
R7213:Naip2	UTSW	13	100,187,483 (GRCm38)	missense	probably damaging	1.00
R7342:Naip2	UTSW	13	100,189,356 (GRCm38)	missense	probably benign	0.09
R7445:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R7572:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R7699:Naip2	UTSW	13	100,160,369 (GRCm38)	missense	probably benign	0.00
R7840:Naip2	UTSW	13	100,144,409 (GRCm38)	missense	probably benign	0.14
R7874:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R7874:Naip2	UTSW	13	100,154,951 (GRCm38)	missense	probably benign	0.00
R8038:Naip2	UTSW	13	100,162,062 (GRCm38)	missense	probably benign	0.00
R8065:Naip2	UTSW	13	100,189,222 (GRCm38)	missense	probably damaging	1.00
R8094:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R8166:Naip2	UTSW	13	100,162,007 (GRCm38)	missense	probably benign	0.03
R8378:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R8669:Naip2	UTSW	13	100,188,969 (GRCm38)	missense	probably benign	0.05
R8691:Naip2	UTSW	13	100,161,168 (GRCm38)	missense	probably damaging	1.00
R8716:Naip2	UTSW	13	100,144,406 (GRCm38)	missense	probably benign
R8720:Naip2	UTSW	13	100,162,122 (GRCm38)	missense	probably benign	0.04
R8888:Naip2	UTSW	13	100,189,136 (GRCm38)	missense	probably benign	0.01
R8895:Naip2	UTSW	13	100,189,136 (GRCm38)	missense	probably benign	0.01
R9031:Naip2	UTSW	13	100,178,268 (GRCm38)	missense	possibly damaging	0.55
R9072:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R9072:Naip2	UTSW	13	100,154,951 (GRCm38)	missense	probably benign	0.00
R9074:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R9074:Naip2	UTSW	13	100,154,951 (GRCm38)	missense	probably benign	0.00
R9077:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R9077:Naip2	UTSW	13	100,154,951 (GRCm38)	missense	probably benign	0.00
R9176:Naip2	UTSW	13	100,162,199 (GRCm38)	missense	probably damaging	1.00
R9219:Naip2	UTSW	13	100,160,705 (GRCm38)	missense	probably benign	0.06
R9371:Naip2	UTSW	13	100,161,846 (GRCm38)	nonsense	probably null
R9414:Naip2	UTSW	13	100,161,735 (GRCm38)	missense	probably damaging	1.00
R9415:Naip2	UTSW	13	100,161,735 (GRCm38)	missense	probably damaging	1.00
R9416:Naip2	UTSW	13	100,161,735 (GRCm38)	missense	probably damaging	1.00
R9708:Naip2	UTSW	13	100,161,579 (GRCm38)	missense	probably damaging	0.99
V5622:Naip2	UTSW	13	100,155,029 (GRCm38)	intron	probably benign
V5622:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
V5622:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
X0063:Naip2	UTSW	13	100,161,758 (GRCm38)	missense	probably damaging	1.00
Y5405:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
Z1088:Naip2	UTSW	13	100,161,909 (GRCm38)	missense	probably benign
Z1176:Naip2	UTSW	13	100,161,909 (GRCm38)	missense	probably benign
Z1176:Naip2	UTSW	13	100,161,593 (GRCm38)	missense	probably benign	0.02
Z1177:Naip2	UTSW	13	100,161,909 (GRCm38)	missense	probably benign
Z1177:Naip2	UTSW	13	100,152,629 (GRCm38)	missense	possibly damaging	0.65
Z1177:Naip2	UTSW	13	100,162,865 (GRCm38)	missense	probably benign	0.01

Predicted Primers

PCR Primer
(F):5'- AAGTGCCACATCCTGAAAGGG -3'
(R):5'- TGTGTCTGAGCAGCATCATC -3'

Sequencing Primer
(F):5'- ACATCCTGAAAGGGCTGGTC -3'
(R):5'- AGTTACAACACCAGGTGCTGTTC -3'

Posted On

2022-04-18