Mutagenetix > Incidental Mutation

Incidental Mutation 'R9373:Tenm2'

709450

Institutional Source

Beutler Lab

Gene Symbol

Tenm2

Ensembl Gene

ENSMUSG00000049336

Gene Name

teneurin transmembrane protein 2

Synonyms

2610040L17Rik, 9330187F13Rik, D3Bwg1534e, Ten-m2, Odz2

MMRRC Submission

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.514) question?

Stock #

R9373 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

36006656-37235964 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 36039886 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Alanine to Threonine at position 1772 (A1772T)

Ref Sequence

ENSEMBL: ENSMUSP00000052014 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057207] [ENSMUST00000102801] [ENSMUST00000163524]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000057207
AA Change: A1772T

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000052014
Gene: ENSMUSG00000049336
AA Change: A1772T

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	374	4.9e-177	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	738	766	9.63e0	SMART
EGF	769	797	1.25e1	SMART
EGF	800	832	1.4e0	SMART
low complexity region	1459	1475	N/A	INTRINSIC
low complexity region	2219	2230	N/A	INTRINSIC
Pfam:Tox-GHH	2681	2758	1.4e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000102801
AA Change: A1771T

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000099865
Gene: ENSMUSG00000049336
AA Change: A1771T

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000163524
AA Change: A1771T

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000129951
Gene: ENSMUSG00000049336
AA Change: A1771T

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 98.8%

Validation Efficiency

96% (53/55)

MGI Phenotype

PHENOTYPE: Mice homozygous for a null allele show abnormalities in the laterality and mapping of ipsilateral retinal projections that lead to loss of ipsilateral drive, defects in binocular vision, and impaired performance on a visual discrimination task. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 55 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2200002D01Rik	CCTTCTCCTTCTTCTCCTTCTTCTCCTTCTTCTCCATCTTCTCCTTCTTC	CCTTCTCCTTCTTCTCCTTCTTCTCCATCTTCTCCTTCTTC	7: 29,247,623 (GRCm38)		probably benign	Het
2310003L06Rik	A	C	5: 87,972,809 (GRCm38)	D475A	probably benign	Het
3110043O21Rik	A	G	4: 35,196,985 (GRCm38)	F360S		Het
Aatk	T	C	11: 120,015,517 (GRCm38)	M243V	possibly damaging	Het
Acox1	A	T	11: 116,174,347 (GRCm38)	N627K	possibly damaging	Het
Adal	A	G	2: 121,150,222 (GRCm38)	Y142C	probably benign	Het
Agfg2	A	G	5: 137,664,214 (GRCm38)		probably null	Het
Ajap1	C	T	4: 153,432,213 (GRCm38)	A224T	probably benign	Het
Alg1	T	C	16: 5,239,126 (GRCm38)	F234L	probably benign	Het
Arhgap27	G	T	11: 103,360,461 (GRCm38)	A147E	possibly damaging	Het
Cachd1	T	C	4: 100,974,870 (GRCm38)	V743A	possibly damaging	Het
Cc2d2b	G	A	19: 40,795,723 (GRCm38)	V655I	unknown	Het
Cd72	T	C	4: 43,450,141 (GRCm38)	S256G	possibly damaging	Het
Celf2	G	T	2: 6,547,104 (GRCm38)	N521K	probably benign	Het
Clca4a	T	A	3: 144,966,372 (GRCm38)	N270Y	possibly damaging	Het
Clvs2	A	T	10: 33,528,386 (GRCm38)	V278E	probably benign	Het
Cwf19l2	T	C	9: 3,454,718 (GRCm38)	F677S	probably damaging	Het
Dusp9	TAAAGCGGAGGCCAAAGCGGAGGCCAAAGCGGAGGCTAAAGCGGAGGCCAAAGCGGAGGCCAAAGCGGAGGCCAAAGCGGAGGCTAAAGCGGAGGCCAAAGCGGAGGCCAAAG	TAAAGCGGAGGCCAAAGCGGAGGCCAAAGCGGAGGCTAAAGCGGAGGCCAAAGCGGAGGCCAAAG	X: 73,640,611 (GRCm38)		probably benign	Het
Dyx1c1	A	G	9: 72,964,180 (GRCm38)	T241A	probably damaging	Het
Epdr1	T	C	13: 19,594,537 (GRCm38)	N130D	possibly damaging	Het
Fam184a	G	A	10: 53,690,019 (GRCm38)	R491W	probably benign	Het
Fam71e2	T	C	7: 4,757,713 (GRCm38)	M667V		Het
Foxp2	A	G	6: 15,377,970 (GRCm38)	Q160R	unknown	Het
Fstl5	T	A	3: 76,648,362 (GRCm38)	Y515*	probably null	Het
Helz2	G	T	2: 181,240,948 (GRCm38)	N17K	probably benign	Het
Jmjd1c	C	T	10: 67,096,716 (GRCm38)		probably benign	Het
Jup	C	T	11: 100,379,565 (GRCm38)	C372Y	probably damaging	Het
Lrrn1	A	C	6: 107,568,504 (GRCm38)	Q421P	possibly damaging	Het
Mapk1	A	G	16: 17,018,290 (GRCm38)	I101V	probably benign	Het
Me2	T	C	18: 73,785,729 (GRCm38)	E427G	probably damaging	Het
Mrc1	G	A	2: 14,270,188 (GRCm38)	M433I	probably damaging	Het
Mrvi1	A	G	7: 110,945,831 (GRCm38)		probably null	Het
Nelfb	G	A	2: 25,205,206 (GRCm38)	R324W	probably damaging	Het
Nlrp4b	T	A	7: 10,715,199 (GRCm38)	I443K	probably benign	Het
Nup210l	C	T	3: 90,199,866 (GRCm38)	P1570L	probably benign	Het
Olfr1012	A	T	2: 85,759,931 (GRCm38)	Y148*	probably null	Het
Olfr1474	A	G	19: 13,471,852 (GRCm38)	E294G	probably damaging	Het
Olfr877	T	A	9: 37,855,454 (GRCm38)	V212D	probably damaging	Het
Olfr914	G	A	9: 38,606,846 (GRCm38)	C127Y	possibly damaging	Het
Parvb	C	T	15: 84,303,899 (GRCm38)	T281I	probably damaging	Het
Prune2	A	G	19: 17,122,138 (GRCm38)	T1669A	probably benign	Het
Runx3	A	G	4: 135,121,145 (GRCm38)	T14A	probably benign	Het
Scn9a	A	G	2: 66,483,917 (GRCm38)	V1819A	probably benign	Het
Senp1	T	C	15: 98,066,554 (GRCm38)	T260A	probably benign	Het
Serpinb10	A	G	1: 107,547,019 (GRCm38)	R304G	possibly damaging	Het
Spem1	C	T	11: 69,821,814 (GRCm38)	C65Y	probably benign	Het
Tdrd6	A	G	17: 43,628,162 (GRCm38)	V665A	possibly damaging	Het
Tenm3	C	T	8: 48,299,655 (GRCm38)	V891I	probably damaging	Het
Trank1	A	G	9: 111,365,191 (GRCm38)	D761G	probably benign	Het
Ubap2l	A	T	3: 90,008,280 (GRCm38)	Y985N	unknown	Het
Vwc2l	A	T	1: 70,729,059 (GRCm38)	H94L	probably damaging	Het
Wdr27	G	A	17: 14,934,533 (GRCm38)	H41Y	probably benign	Het
Zcchc6	T	C	13: 59,796,867 (GRCm38)	S1053G	probably damaging	Het
Zfp7	AGTGCGGGAAAGGTTTCCACCTG	AG	15: 76,890,598 (GRCm38)		probably benign	Het
Zfp7	TGCGGGAAAGGTTTCCACCTGAGCG	TGCG	15: 76,890,600 (GRCm38)		probably benign	Het

Other mutations in Tenm2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Tenm2	APN	11	36,206,899 (GRCm38)	splice site	probably benign
IGL00834:Tenm2	APN	11	36,024,258 (GRCm38)	missense	probably damaging	1.00
IGL00911:Tenm2	APN	11	36,008,733 (GRCm38)	nonsense	probably null
IGL00937:Tenm2	APN	11	36,024,623 (GRCm38)	missense	probably damaging	1.00
IGL01154:Tenm2	APN	11	36,041,544 (GRCm38)	missense	probably damaging	1.00
IGL01313:Tenm2	APN	11	36,024,248 (GRCm38)	missense	probably damaging	0.98
IGL01346:Tenm2	APN	11	36,027,405 (GRCm38)	nonsense	probably null
IGL01539:Tenm2	APN	11	36,106,827 (GRCm38)	missense	possibly damaging	0.89
IGL01629:Tenm2	APN	11	36,864,884 (GRCm38)	missense	probably damaging	0.98
IGL01780:Tenm2	APN	11	36,046,941 (GRCm38)	missense	probably benign
IGL01821:Tenm2	APN	11	36,023,883 (GRCm38)	missense	probably damaging	0.98
IGL01988:Tenm2	APN	11	36,027,251 (GRCm38)	missense	probably damaging	1.00
IGL02002:Tenm2	APN	11	36,207,095 (GRCm38)	missense	probably benign
IGL02449:Tenm2	APN	11	36,023,622 (GRCm38)	missense	probably damaging	0.99
IGL02505:Tenm2	APN	11	36,051,916 (GRCm38)	nonsense	probably null
IGL02649:Tenm2	APN	11	36,207,085 (GRCm38)	missense	possibly damaging	0.85
IGL02688:Tenm2	APN	11	36,068,458 (GRCm38)	missense	probably benign	0.05
IGL02801:Tenm2	APN	11	36,047,030 (GRCm38)	nonsense	probably null
IGL02928:Tenm2	APN	11	36,027,170 (GRCm38)	missense	possibly damaging	0.69
IGL02940:Tenm2	APN	11	36,041,644 (GRCm38)	missense	probably damaging	1.00
IGL03202:Tenm2	APN	11	36,024,548 (GRCm38)	missense	probably damaging	1.00
IGL03213:Tenm2	APN	11	36,023,330 (GRCm38)	missense	probably benign	0.05
IGL03276:Tenm2	APN	11	36,072,776 (GRCm38)	missense	possibly damaging	0.95
IGL03296:Tenm2	APN	11	36,052,025 (GRCm38)	splice site	probably null
IGL03381:Tenm2	APN	11	36,068,411 (GRCm38)	missense	probably benign	0.01
IGL03398:Tenm2	APN	11	36,024,543 (GRCm38)	missense	probably damaging	1.00
browser	UTSW	11	36,046,765 (GRCm38)	critical splice donor site	probably null
mosaic	UTSW	11	36,063,775 (GRCm38)	critical splice donor site	probably null
IGL02799:Tenm2	UTSW	11	36,273,408 (GRCm38)	missense	probably damaging	1.00
PIT4260001:Tenm2	UTSW	11	36,163,730 (GRCm38)	missense	probably damaging	1.00
PIT4382001:Tenm2	UTSW	11	36,063,902 (GRCm38)	missense	probably damaging	0.99
R0004:Tenm2	UTSW	11	36,023,357 (GRCm38)	missense	probably damaging	1.00
R0420:Tenm2	UTSW	11	36,207,124 (GRCm38)	splice site	probably benign
R0537:Tenm2	UTSW	11	36,163,730 (GRCm38)	missense	probably damaging	1.00
R0599:Tenm2	UTSW	11	36,024,780 (GRCm38)	missense	possibly damaging	0.93
R0636:Tenm2	UTSW	11	36,943,976 (GRCm38)	missense	probably damaging	1.00
R0693:Tenm2	UTSW	11	36,024,809 (GRCm38)	missense	probably damaging	1.00
R0991:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R0992:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1167:Tenm2	UTSW	11	36,864,684 (GRCm38)	missense	probably benign	0.30
R1177:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1178:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1179:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1180:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1181:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1193:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1194:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1259:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1265:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1267:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1268:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1269:Tenm2	UTSW	11	36,008,358 (GRCm38)	missense	possibly damaging	0.64
R1270:Tenm2	UTSW	11	36,041,659 (GRCm38)	missense	probably damaging	1.00
R1272:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1273:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1311:Tenm2	UTSW	11	36,068,594 (GRCm38)	splice site	probably benign
R1374:Tenm2	UTSW	11	36,008,454 (GRCm38)	missense	probably benign	0.00
R1542:Tenm2	UTSW	11	36,300,220 (GRCm38)	missense	probably damaging	0.99
R1573:Tenm2	UTSW	11	36,047,069 (GRCm38)	missense	probably damaging	1.00
R1579:Tenm2	UTSW	11	36,106,783 (GRCm38)	missense	probably damaging	1.00
R1697:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1722:Tenm2	UTSW	11	36,008,103 (GRCm38)	missense	probably damaging	1.00
R1756:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1793:Tenm2	UTSW	11	36,023,382 (GRCm38)	missense	probably damaging	0.99
R1950:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1954:Tenm2	UTSW	11	36,047,547 (GRCm38)	missense	possibly damaging	0.87
R2025:Tenm2	UTSW	11	36,047,264 (GRCm38)	nonsense	probably null
R2117:Tenm2	UTSW	11	36,024,854 (GRCm38)	missense	probably damaging	1.00
R2244:Tenm2	UTSW	11	36,864,862 (GRCm38)	missense	probably damaging	0.98
R2298:Tenm2	UTSW	11	36,046,777 (GRCm38)	missense	possibly damaging	0.62
R2432:Tenm2	UTSW	11	36,027,191 (GRCm38)	missense	probably damaging	1.00
R3014:Tenm2	UTSW	11	36,023,973 (GRCm38)	missense	probably damaging	1.00
R3115:Tenm2	UTSW	11	36,023,366 (GRCm38)	missense	probably damaging	1.00
R3684:Tenm2	UTSW	11	36,051,817 (GRCm38)	missense	probably benign	0.00
R3685:Tenm2	UTSW	11	36,051,817 (GRCm38)	missense	probably benign	0.00
R3705:Tenm2	UTSW	11	36,068,326 (GRCm38)	missense	probably damaging	0.97
R3820:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3821:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3822:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3844:Tenm2	UTSW	11	36,047,538 (GRCm38)	missense	probably damaging	0.98
R3878:Tenm2	UTSW	11	36,139,574 (GRCm38)	critical splice donor site	probably null
R4019:Tenm2	UTSW	11	36,047,074 (GRCm38)	missense	probably benign	0.04
R4062:Tenm2	UTSW	11	36,008,655 (GRCm38)	missense	probably damaging	1.00
R4367:Tenm2	UTSW	11	36,027,398 (GRCm38)	missense	probably benign
R4395:Tenm2	UTSW	11	36,024,624 (GRCm38)	missense	probably benign	0.23
R4508:Tenm2	UTSW	11	36,008,345 (GRCm38)	missense	possibly damaging	0.82
R4534:Tenm2	UTSW	11	36,063,104 (GRCm38)	missense	possibly damaging	0.64
R4539:Tenm2	UTSW	11	36,046,780 (GRCm38)	missense	probably damaging	1.00
R4644:Tenm2	UTSW	11	36,047,136 (GRCm38)	missense	probably benign	0.00
R4661:Tenm2	UTSW	11	36,024,448 (GRCm38)	missense	probably damaging	0.99
R4669:Tenm2	UTSW	11	36,010,487 (GRCm38)	missense	probably damaging	1.00
R4687:Tenm2	UTSW	11	36,049,097 (GRCm38)	missense	probably benign
R4711:Tenm2	UTSW	11	36,300,212 (GRCm38)	missense	probably damaging	0.98
R4816:Tenm2	UTSW	11	36,027,290 (GRCm38)	missense	probably damaging	1.00
R4843:Tenm2	UTSW	11	36,024,020 (GRCm38)	missense	probably damaging	1.00
R4850:Tenm2	UTSW	11	36,023,488 (GRCm38)	nonsense	probably null
R4870:Tenm2	UTSW	11	36,078,569 (GRCm38)	missense	probably damaging	1.00
R5058:Tenm2	UTSW	11	36,207,080 (GRCm38)	missense	possibly damaging	0.80
R5071:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5073:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5074:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5081:Tenm2	UTSW	11	36,024,633 (GRCm38)	missense	possibly damaging	0.95
R5093:Tenm2	UTSW	11	36,944,162 (GRCm38)	missense	probably damaging	1.00
R5170:Tenm2	UTSW	11	36,024,806 (GRCm38)	missense	probably damaging	0.98
R5253:Tenm2	UTSW	11	36,047,201 (GRCm38)	nonsense	probably null
R5343:Tenm2	UTSW	11	36,069,503 (GRCm38)	missense	probably benign	0.00
R5493:Tenm2	UTSW	11	36,864,676 (GRCm38)	missense	probably benign	0.01
R5600:Tenm2	UTSW	11	36,163,714 (GRCm38)	splice site	probably null
R5677:Tenm2	UTSW	11	36,141,683 (GRCm38)	missense	probably damaging	0.98
R5703:Tenm2	UTSW	11	36,023,799 (GRCm38)	missense	probably benign	0.34
R5707:Tenm2	UTSW	11	36,047,182 (GRCm38)	missense	possibly damaging	0.79
R6026:Tenm2	UTSW	11	36,072,729 (GRCm38)	critical splice donor site	probably null
R6063:Tenm2	UTSW	11	36,163,717 (GRCm38)	critical splice donor site	probably null
R6086:Tenm2	UTSW	11	36,008,646 (GRCm38)	missense	possibly damaging	0.64
R6151:Tenm2	UTSW	11	36,008,783 (GRCm38)	missense	probably damaging	1.00
R6169:Tenm2	UTSW	11	36,139,690 (GRCm38)	missense	probably damaging	0.99
R6193:Tenm2	UTSW	11	36,046,794 (GRCm38)	missense	probably damaging	1.00
R6405:Tenm2	UTSW	11	36,864,859 (GRCm38)	missense	probably benign	0.44
R6477:Tenm2	UTSW	11	36,010,507 (GRCm38)	critical splice acceptor site	probably null
R6607:Tenm2	UTSW	11	36,063,775 (GRCm38)	critical splice donor site	probably null
R6668:Tenm2	UTSW	11	36,046,765 (GRCm38)	critical splice donor site	probably null
R6825:Tenm2	UTSW	11	36,046,884 (GRCm38)	missense	probably benign	0.02
R6885:Tenm2	UTSW	11	36,023,580 (GRCm38)	missense	possibly damaging	0.95
R7017:Tenm2	UTSW	11	36,171,409 (GRCm38)	missense	probably damaging	0.98
R7115:Tenm2	UTSW	11	36,163,817 (GRCm38)	missense	probably damaging	0.99
R7153:Tenm2	UTSW	11	36,024,182 (GRCm38)	missense	probably damaging	0.98
R7173:Tenm2	UTSW	11	36,041,551 (GRCm38)	missense	probably damaging	0.99
R7199:Tenm2	UTSW	11	36,171,436 (GRCm38)	missense	probably damaging	1.00
R7205:Tenm2	UTSW	11	36,049,129 (GRCm38)	missense	probably damaging	0.99
R7250:Tenm2	UTSW	11	36,072,798 (GRCm38)	missense	probably damaging	1.00
R7290:Tenm2	UTSW	11	36,023,471 (GRCm38)	missense	probably damaging	1.00
R7366:Tenm2	UTSW	11	36,069,414 (GRCm38)	missense	probably benign	0.09
R7432:Tenm2	UTSW	11	36,864,941 (GRCm38)	missense	probably benign
R7504:Tenm2	UTSW	11	36,139,743 (GRCm38)	missense	probably damaging	1.00
R7513:Tenm2	UTSW	11	36,051,900 (GRCm38)	missense	probably benign	0.34
R7523:Tenm2	UTSW	11	36,078,581 (GRCm38)	splice site	probably null
R7527:Tenm2	UTSW	11	36,206,976 (GRCm38)	missense	probably damaging	1.00
R7648:Tenm2	UTSW	11	36,106,736 (GRCm38)	missense	probably damaging	1.00
R7653:Tenm2	UTSW	11	36,047,347 (GRCm38)	missense	probably benign	0.09
R7717:Tenm2	UTSW	11	36,864,935 (GRCm38)	missense	probably damaging	0.97
R7739:Tenm2	UTSW	11	36,069,561 (GRCm38)	missense	possibly damaging	0.50
R7762:Tenm2	UTSW	11	36,023,306 (GRCm38)	missense	possibly damaging	0.74
R7786:Tenm2	UTSW	11	36,010,449 (GRCm38)	missense	probably damaging	0.99
R7803:Tenm2	UTSW	11	36,047,116 (GRCm38)	missense	probably damaging	0.98
R7834:Tenm2	UTSW	11	36,024,854 (GRCm38)	missense	probably damaging	1.00
R7838:Tenm2	UTSW	11	36,106,799 (GRCm38)	missense	probably benign	0.02
R8073:Tenm2	UTSW	11	36,139,644 (GRCm38)	missense	possibly damaging	0.56
R8076:Tenm2	UTSW	11	36,027,221 (GRCm38)	missense	probably benign	0.23
R8109:Tenm2	UTSW	11	36,008,310 (GRCm38)	missense	probably benign
R8306:Tenm2	UTSW	11	36,069,369 (GRCm38)	missense	possibly damaging	0.52
R8352:Tenm2	UTSW	11	36,023,601 (GRCm38)	missense	probably damaging	0.98
R8452:Tenm2	UTSW	11	36,023,601 (GRCm38)	missense	probably damaging	0.98
R8864:Tenm2	UTSW	11	36,027,195 (GRCm38)	missense	possibly damaging	0.95
R8880:Tenm2	UTSW	11	36,051,961 (GRCm38)	missense	probably damaging	0.99
R8943:Tenm2	UTSW	11	36,944,034 (GRCm38)	missense	probably damaging	0.98
R8969:Tenm2	UTSW	11	36,051,861 (GRCm38)	missense	probably damaging	0.99
R9168:Tenm2	UTSW	11	36,039,895 (GRCm38)	missense	probably damaging	1.00
R9279:Tenm2	UTSW	11	36,068,476 (GRCm38)	missense	probably benign	0.00
R9294:Tenm2	UTSW	11	36,024,500 (GRCm38)	missense	probably damaging	0.98
R9320:Tenm2	UTSW	11	36,023,647 (GRCm38)	missense	probably damaging	0.99
R9408:Tenm2	UTSW	11	36,069,419 (GRCm38)	missense	probably damaging	1.00
R9410:Tenm2	UTSW	11	36,141,569 (GRCm38)	missense	probably damaging	0.99
R9454:Tenm2	UTSW	11	36,221,459 (GRCm38)	missense	probably benign
R9489:Tenm2	UTSW	11	36,943,964 (GRCm38)	missense	probably damaging	0.99
R9711:Tenm2	UTSW	11	36,024,514 (GRCm38)	missense	probably damaging	0.99
RF021:Tenm2	UTSW	11	36,024,203 (GRCm38)	missense	possibly damaging	0.95
X0018:Tenm2	UTSW	11	36,024,200 (GRCm38)	missense	probably damaging	1.00
X0063:Tenm2	UTSW	11	36,024,730 (GRCm38)	missense	probably benign
Z1088:Tenm2	UTSW	11	36,273,267 (GRCm38)	missense	probably damaging	1.00
Z1177:Tenm2	UTSW	11	36,300,335 (GRCm38)	missense	probably damaging	0.98
Z1177:Tenm2	UTSW	11	36,008,234 (GRCm38)	missense	possibly damaging	0.95
Z1177:Tenm2	UTSW	11	36,385,130 (GRCm38)	missense	probably benign	0.01

Predicted Primers

PCR Primer
(F):5'- AGCTTCCTCCCAAAGATGGTG -3'
(R):5'- CCCGTGGATCAGTAGCATCTTC -3'

Sequencing Primer
(F):5'- CAAAGATGGTGACTTTGCCTTTGATC -3'
(R):5'- TGCTAATTGAAGGCAGCCTC -3'

Posted On

2022-04-18