Incidental Mutation 'R9377:Mical2'
| ID |
709697 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mical2
|
| Ensembl Gene |
ENSMUSG00000038244 |
| Gene Name |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| Synonyms |
4921517J23Rik, Ebitein1, 5330438E18Rik, Micalcl |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.298)
|
| Stock # |
R9377 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
111825063-112012313 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 111981246 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Phenylalanine
at position 407
(L407F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000062443
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033033]
[ENSMUST00000051308]
[ENSMUST00000106645]
|
| AlphaFold |
Q8BML1
Q9D5U9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000033033
AA Change: L473F
PolyPhen 2
Score 0.213 (Sensitivity: 0.92; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000033033
Gene: ENSMUSG00000030771
AA Change: L473F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
100 |
N/A |
INTRINSIC |
|
low complexity region
|
393 |
404 |
N/A |
INTRINSIC |
|
low complexity region
|
415 |
432 |
N/A |
INTRINSIC |
|
low complexity region
|
545 |
562 |
N/A |
INTRINSIC |
|
coiled coil region
|
569 |
597 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000051308
AA Change: L407F
PolyPhen 2
Score 0.097 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000062443
Gene: ENSMUSG00000030771
AA Change: L407F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
low complexity region
|
349 |
366 |
N/A |
INTRINSIC |
|
low complexity region
|
479 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
DUF3585
|
526 |
668 |
6.86e-56 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106645
AA Change: L407F
PolyPhen 2
Score 0.097 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000102256
Gene: ENSMUSG00000030771
AA Change: L407F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
low complexity region
|
349 |
366 |
N/A |
INTRINSIC |
|
low complexity region
|
479 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
DUF3585
|
526 |
668 |
6.86e-56 |
SMART |
|
| Predicted Effect |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000215412
|
| Predicted Effect |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700122O11Rik |
T |
C |
17: 48,348,273 (GRCm39) |
T55A |
probably benign |
Het |
| 3110070M22Rik |
T |
A |
13: 119,624,822 (GRCm39) |
|
probably benign |
Het |
| Acot12 |
T |
A |
13: 91,918,221 (GRCm39) |
N171K |
probably benign |
Het |
| Adam18 |
G |
A |
8: 25,104,859 (GRCm39) |
Q652* |
probably null |
Het |
| Adgrv1 |
T |
C |
13: 81,705,277 (GRCm39) |
E791G |
probably damaging |
Het |
| Aff1 |
C |
T |
5: 103,981,685 (GRCm39) |
S608L |
probably damaging |
Het |
| Amfr |
A |
T |
8: 94,707,018 (GRCm39) |
F432L |
probably damaging |
Het |
| Ankfn1 |
G |
A |
11: 89,332,284 (GRCm39) |
L421F |
possibly damaging |
Het |
| Ankrd31 |
T |
C |
13: 97,014,733 (GRCm39) |
V1334A |
probably benign |
Het |
| Ascc3 |
C |
T |
10: 50,608,858 (GRCm39) |
H1534Y |
possibly damaging |
Het |
| Aste1 |
G |
A |
9: 105,273,880 (GRCm39) |
C40Y |
probably benign |
Het |
| Atf3 |
T |
C |
1: 190,909,510 (GRCm39) |
H53R |
probably benign |
Het |
| Bsn |
C |
A |
9: 107,990,800 (GRCm39) |
V1651F |
probably damaging |
Het |
| Bsn |
A |
T |
9: 107,993,361 (GRCm39) |
L797Q |
probably damaging |
Het |
| Bzw2 |
T |
C |
12: 36,180,131 (GRCm39) |
D32G |
probably damaging |
Het |
| Cacna1e |
A |
T |
1: 154,361,458 (GRCm39) |
M531K |
possibly damaging |
Het |
| Cep120 |
A |
G |
18: 53,851,592 (GRCm39) |
F567L |
possibly damaging |
Het |
| Cit |
T |
C |
5: 116,084,914 (GRCm39) |
I815T |
probably benign |
Het |
| Cnot6l |
G |
T |
5: 96,276,826 (GRCm39) |
Q121K |
probably benign |
Het |
| Col4a2 |
G |
A |
8: 11,483,725 (GRCm39) |
G882R |
probably damaging |
Het |
| Col6a3 |
A |
G |
1: 90,743,961 (GRCm39) |
F536L |
probably damaging |
Het |
| Copg2 |
T |
A |
6: 30,793,721 (GRCm39) |
H394L |
possibly damaging |
Het |
| Cst13 |
A |
G |
2: 148,670,165 (GRCm39) |
M112V |
possibly damaging |
Het |
| Cyp2j7 |
G |
T |
4: 96,124,786 (GRCm39) |
N37K |
probably benign |
Het |
| Cyp2u1 |
T |
A |
3: 131,091,449 (GRCm39) |
N357I |
possibly damaging |
Het |
| Dars1 |
T |
C |
1: 128,344,945 (GRCm39) |
T4A |
probably benign |
Het |
| Dclk1 |
G |
T |
3: 55,429,374 (GRCm39) |
C414F |
possibly damaging |
Het |
| Dmbt1 |
A |
T |
7: 130,694,832 (GRCm39) |
Y1009F |
unknown |
Het |
| Ebf4 |
T |
C |
2: 130,148,775 (GRCm39) |
Y117H |
probably damaging |
Het |
| Eif2b4 |
A |
G |
5: 31,348,500 (GRCm39) |
Y196H |
probably benign |
Het |
| Enpp2 |
C |
T |
15: 54,739,080 (GRCm39) |
R401H |
probably damaging |
Het |
| Epo |
T |
C |
5: 137,484,017 (GRCm39) |
|
probably benign |
Het |
| Gli1 |
T |
A |
10: 127,173,359 (GRCm39) |
T100S |
possibly damaging |
Het |
| Gml2 |
T |
A |
15: 74,695,957 (GRCm39) |
F117Y |
probably benign |
Het |
| Hivep1 |
T |
C |
13: 42,335,403 (GRCm39) |
V2314A |
probably benign |
Het |
| Hspb8 |
A |
G |
5: 116,547,487 (GRCm39) |
I165T |
probably damaging |
Het |
| Itgax |
A |
T |
7: 127,732,849 (GRCm39) |
T243S |
probably benign |
Het |
| Itih4 |
G |
T |
14: 30,608,533 (GRCm39) |
L16F |
probably damaging |
Het |
| Kmt5a |
C |
T |
5: 124,578,064 (GRCm39) |
|
probably benign |
Het |
| Lamc1 |
T |
C |
1: 153,115,009 (GRCm39) |
E1089G |
probably benign |
Het |
| Ltbp2 |
G |
A |
12: 84,837,864 (GRCm39) |
P1192L |
probably benign |
Het |
| Mcmbp |
A |
T |
7: 128,317,803 (GRCm39) |
N147K |
probably benign |
Het |
| Mybpc2 |
A |
T |
7: 44,158,999 (GRCm39) |
V653D |
probably benign |
Het |
| Myo3b |
G |
A |
2: 70,069,242 (GRCm39) |
V522I |
possibly damaging |
Het |
| Nbr1 |
A |
G |
11: 101,456,590 (GRCm39) |
T156A |
possibly damaging |
Het |
| Neb |
T |
A |
2: 52,039,291 (GRCm39) |
|
probably null |
Het |
| Neb |
T |
A |
2: 52,116,546 (GRCm39) |
Y964F |
|
Het |
| Nr2f2 |
T |
A |
7: 70,007,856 (GRCm39) |
I209F |
probably damaging |
Het |
| Nwd2 |
A |
G |
5: 63,957,740 (GRCm39) |
T357A |
probably damaging |
Het |
| Palld |
C |
T |
8: 61,969,691 (GRCm39) |
R1211H |
unknown |
Het |
| Pcdhb19 |
T |
A |
18: 37,632,299 (GRCm39) |
V698E |
probably damaging |
Het |
| Pcdhga6 |
C |
T |
18: 37,841,570 (GRCm39) |
P430L |
probably damaging |
Het |
| Piezo2 |
A |
G |
18: 63,162,156 (GRCm39) |
L2225S |
possibly damaging |
Het |
| Plekhf1 |
A |
T |
7: 37,921,203 (GRCm39) |
W122R |
probably damaging |
Het |
| Pold3 |
A |
G |
7: 99,732,993 (GRCm39) |
S418P |
possibly damaging |
Het |
| Poldip3 |
T |
C |
15: 83,019,589 (GRCm39) |
N180S |
probably benign |
Het |
| Ppp1r21 |
C |
T |
17: 88,852,815 (GRCm39) |
R65* |
probably null |
Het |
| Ppp1r3d |
A |
T |
2: 178,055,669 (GRCm39) |
V111E |
probably damaging |
Het |
| Prrg4 |
T |
C |
2: 104,669,728 (GRCm39) |
I130V |
probably benign |
Het |
| Psma5 |
A |
T |
3: 108,172,448 (GRCm39) |
T55S |
probably benign |
Het |
| Rbm5 |
C |
A |
9: 107,627,252 (GRCm39) |
A440S |
probably benign |
Het |
| Rdx |
A |
G |
9: 51,980,168 (GRCm39) |
K254E |
possibly damaging |
Het |
| Rere |
A |
C |
4: 150,593,342 (GRCm39) |
Q312P |
unknown |
Het |
| Rest |
T |
C |
5: 77,416,128 (GRCm39) |
V114A |
possibly damaging |
Het |
| Rufy4 |
G |
T |
1: 74,171,879 (GRCm39) |
V201L |
probably benign |
Het |
| Scyl1 |
T |
C |
19: 5,809,023 (GRCm39) |
E727G |
probably benign |
Het |
| Serpinb6b |
T |
A |
13: 33,152,494 (GRCm39) |
M1K |
probably null |
Het |
| Sgsm1 |
C |
A |
5: 113,436,741 (GRCm39) |
V30F |
probably damaging |
Het |
| Skap1 |
A |
G |
11: 96,644,921 (GRCm39) |
D344G |
possibly damaging |
Het |
| Slc26a7 |
T |
C |
4: 14,516,189 (GRCm39) |
T547A |
probably benign |
Het |
| Slc6a3 |
C |
A |
13: 73,692,966 (GRCm39) |
S195R |
probably benign |
Het |
| Sorbs1 |
T |
C |
19: 40,387,048 (GRCm39) |
D6G |
probably damaging |
Het |
| Spock3 |
A |
T |
8: 63,798,746 (GRCm39) |
M253L |
probably damaging |
Het |
| Ssh2 |
A |
G |
11: 77,298,974 (GRCm39) |
Y107C |
possibly damaging |
Het |
| Svil |
T |
C |
18: 5,057,294 (GRCm39) |
S581P |
probably benign |
Het |
| Tbc1d14 |
T |
C |
5: 36,662,472 (GRCm39) |
T553A |
probably benign |
Het |
| Tet3 |
T |
A |
6: 83,380,596 (GRCm39) |
Q524L |
possibly damaging |
Het |
| Uckl1 |
A |
T |
2: 181,211,532 (GRCm39) |
V456E |
probably damaging |
Het |
| Ucp2 |
T |
C |
7: 100,146,040 (GRCm39) |
F4S |
probably benign |
Het |
| Vmn2r77 |
A |
G |
7: 86,444,442 (GRCm39) |
I32V |
probably benign |
Het |
| Vmn2r89 |
T |
A |
14: 51,692,601 (GRCm39) |
Y135N |
probably benign |
Het |
| Vtn |
A |
G |
11: 78,390,587 (GRCm39) |
E82G |
probably benign |
Het |
| Zfp758 |
A |
G |
17: 22,593,925 (GRCm39) |
N137S |
probably benign |
Het |
| Zgpat |
T |
A |
2: 181,021,646 (GRCm39) |
C357* |
probably null |
Het |
|
| Other mutations in Mical2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Mical2
|
APN |
7 |
111,981,352 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00886:Mical2
|
APN |
7 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00934:Mical2
|
APN |
7 |
111,948,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00941:Mical2
|
APN |
7 |
111,920,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01020:Mical2
|
APN |
7 |
111,914,283 (GRCm39) |
splice site |
probably benign |
|
|
IGL01395:Mical2
|
APN |
7 |
111,922,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01658:Mical2
|
APN |
7 |
111,914,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01775:Mical2
|
APN |
7 |
111,981,269 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02040:Mical2
|
APN |
7 |
111,910,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02051:Mical2
|
APN |
7 |
111,980,597 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02388:Mical2
|
APN |
7 |
111,934,620 (GRCm39) |
missense |
probably benign |
|
|
IGL02551:Mical2
|
APN |
7 |
111,923,197 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02578:Mical2
|
APN |
7 |
111,950,580 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02751:Mical2
|
APN |
7 |
111,931,243 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03114:Mical2
|
APN |
7 |
111,996,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0091:Mical2
|
UTSW |
7 |
111,980,503 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0101:Mical2
|
UTSW |
7 |
111,936,074 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0415:Mical2
|
UTSW |
7 |
111,980,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Mical2
|
UTSW |
7 |
111,870,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0594:Mical2
|
UTSW |
7 |
111,917,657 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0609:Mical2
|
UTSW |
7 |
111,920,647 (GRCm39) |
splice site |
probably null |
|
|
R0962:Mical2
|
UTSW |
7 |
111,979,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1521:Mical2
|
UTSW |
7 |
111,980,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mical2
|
UTSW |
7 |
111,908,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1611:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1740:Mical2
|
UTSW |
7 |
111,933,043 (GRCm39) |
missense |
probably benign |
|
|
R1815:Mical2
|
UTSW |
7 |
112,012,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mical2
|
UTSW |
7 |
111,944,489 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1958:Mical2
|
UTSW |
7 |
111,980,311 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1962:Mical2
|
UTSW |
7 |
112,012,051 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2086:Mical2
|
UTSW |
7 |
111,917,810 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2136:Mical2
|
UTSW |
7 |
111,870,722 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2418:Mical2
|
UTSW |
7 |
111,919,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2439:Mical2
|
UTSW |
7 |
111,994,002 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3053:Mical2
|
UTSW |
7 |
111,910,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Mical2
|
UTSW |
7 |
112,006,885 (GRCm39) |
splice site |
probably null |
|
|
R4308:Mical2
|
UTSW |
7 |
111,931,199 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4551:Mical2
|
UTSW |
7 |
111,981,123 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4583:Mical2
|
UTSW |
7 |
112,012,154 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4663:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4868:Mical2
|
UTSW |
7 |
111,917,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Mical2
|
UTSW |
7 |
111,936,107 (GRCm39) |
missense |
probably benign |
|
|
R5112:Mical2
|
UTSW |
7 |
111,919,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Mical2
|
UTSW |
7 |
111,981,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5487:Mical2
|
UTSW |
7 |
111,919,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5563:Mical2
|
UTSW |
7 |
111,914,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5763:Mical2
|
UTSW |
7 |
111,973,861 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5817:Mical2
|
UTSW |
7 |
111,922,866 (GRCm39) |
missense |
probably benign |
|
|
R5987:Mical2
|
UTSW |
7 |
111,934,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6042:Mical2
|
UTSW |
7 |
111,979,619 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6087:Mical2
|
UTSW |
7 |
111,917,692 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Mical2
|
UTSW |
7 |
112,012,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Mical2
|
UTSW |
7 |
111,923,293 (GRCm39) |
splice site |
probably null |
|
|
R6311:Mical2
|
UTSW |
7 |
111,922,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6319:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6578:Mical2
|
UTSW |
7 |
111,910,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6750:Mical2
|
UTSW |
7 |
111,981,046 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6782:Mical2
|
UTSW |
7 |
111,945,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Mical2
|
UTSW |
7 |
111,975,266 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R7061:Mical2
|
UTSW |
7 |
111,946,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7147:Mical2
|
UTSW |
7 |
111,922,810 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7260:Mical2
|
UTSW |
7 |
111,919,001 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7266:Mical2
|
UTSW |
7 |
111,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Mical2
|
UTSW |
7 |
111,981,358 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7391:Mical2
|
UTSW |
7 |
111,919,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7747:Mical2
|
UTSW |
7 |
111,933,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Mical2
|
UTSW |
7 |
112,012,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Mical2
|
UTSW |
7 |
111,944,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Mical2
|
UTSW |
7 |
112,006,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Mical2
|
UTSW |
7 |
111,980,975 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8022:Mical2
|
UTSW |
7 |
111,902,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Mical2
|
UTSW |
7 |
111,944,460 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8505:Mical2
|
UTSW |
7 |
111,919,007 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8532:Mical2
|
UTSW |
7 |
111,917,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8830:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8862:Mical2
|
UTSW |
7 |
111,910,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8988:Mical2
|
UTSW |
7 |
111,910,661 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9006:Mical2
|
UTSW |
7 |
111,981,323 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9123:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9127:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9128:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9129:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9140:Mical2
|
UTSW |
7 |
112,006,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9187:Mical2
|
UTSW |
7 |
111,902,797 (GRCm39) |
nonsense |
probably null |
|
|
R9233:Mical2
|
UTSW |
7 |
111,981,399 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9304:Mical2
|
UTSW |
7 |
111,980,974 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9310:Mical2
|
UTSW |
7 |
111,950,920 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9399:Mical2
|
UTSW |
7 |
111,946,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Mical2
|
UTSW |
7 |
112,010,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9500:Mical2
|
UTSW |
7 |
111,936,054 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9620:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9652:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Mical2
|
UTSW |
7 |
111,921,806 (GRCm39) |
missense |
probably benign |
0.37 |
|
R9756:Mical2
|
UTSW |
7 |
111,902,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9789:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Mical2
|
UTSW |
7 |
111,946,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTAAGGTTGCCCAAGCCTC -3'
(R):5'- TACGTGCATCTTGCCCTGTG -3'
Sequencing Primer
(F):5'- TTGCCCAAGCCTCAGACCTTAG -3'
(R):5'- CATCTTGCCCTGTGGAAGAAG -3'
|
| Posted On |
2022-04-18 |
Incidental Mutation