Incidental Mutation 'R9377:Col4a2'
| ID |
709701 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Col4a2
|
| Ensembl Gene |
ENSMUSG00000031503 |
| Gene Name |
collagen, type IV, alpha 2 |
| Synonyms |
Col4a-2 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9377 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
11362805-11499287 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 11483725 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Arginine
at position 882
(G882R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000033899
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033899]
|
| AlphaFold |
P08122 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000033899
AA Change: G882R
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000033899
Gene: ENSMUSG00000031503
AA Change: G882R
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Pfam:Collagen
|
56 |
119 |
1.2e-10 |
PFAM |
|
Pfam:Collagen
|
112 |
174 |
3.9e-8 |
PFAM |
|
low complexity region
|
193 |
229 |
N/A |
INTRINSIC |
|
Pfam:Collagen
|
289 |
348 |
1.3e-10 |
PFAM |
|
low complexity region
|
370 |
389 |
N/A |
INTRINSIC |
|
low complexity region
|
427 |
445 |
N/A |
INTRINSIC |
|
Pfam:Collagen
|
488 |
546 |
2e-10 |
PFAM |
|
Pfam:Collagen
|
590 |
655 |
4.5e-9 |
PFAM |
|
low complexity region
|
665 |
673 |
N/A |
INTRINSIC |
|
Pfam:Collagen
|
674 |
731 |
3.5e-10 |
PFAM |
|
Pfam:Collagen
|
714 |
775 |
4.3e-10 |
PFAM |
|
Pfam:Collagen
|
773 |
831 |
1.5e-10 |
PFAM |
|
Pfam:Collagen
|
861 |
935 |
8.1e-10 |
PFAM |
|
Pfam:Collagen
|
915 |
976 |
1.1e-9 |
PFAM |
|
Pfam:Collagen
|
978 |
1038 |
2.6e-8 |
PFAM |
|
Pfam:Collagen
|
1027 |
1091 |
1.7e-10 |
PFAM |
|
Pfam:Collagen
|
1094 |
1155 |
5.5e-11 |
PFAM |
|
Pfam:Collagen
|
1147 |
1211 |
1e-10 |
PFAM |
|
Pfam:Collagen
|
1271 |
1340 |
2.1e-8 |
PFAM |
|
Pfam:Collagen
|
1330 |
1392 |
7.1e-10 |
PFAM |
|
C4
|
1484 |
1591 |
7.85e-59 |
SMART |
|
C4
|
1592 |
1706 |
7.65e-71 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes the alpha-2 subunit of the type IV collagens, an essential component of basement membranes. The encoded protein forms a triple helical heterotrimer comprised of alpha-1 and alpha-2 subunits that assembles into a type IV collagen network. Canstatin, a peptide derived fom the C-terminus of the collagen chain, is a matrikine that has been shown to inhibit angiogenesis. Homozygous knockout mice for this gene exhibit impaired basement membrane integrity and embryonic lethality. This gene shares a bi-directional promoter with a related gene on chromosome 8. [provided by RefSeq, Nov 2015]
PHENOTYPE: ENU-induced missense mutations of this gene result in a variable phenotype affecting the eye, brain and vascular stability in heterozygotes, and fetal or postnatal survival in homozygotes. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(10) : Targeted, knock-out(1) Gene trapped(6) Chemically induced(3) |
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700122O11Rik |
T |
C |
17: 48,348,273 (GRCm39) |
T55A |
probably benign |
Het |
| 3110070M22Rik |
T |
A |
13: 119,624,822 (GRCm39) |
|
probably benign |
Het |
| Acot12 |
T |
A |
13: 91,918,221 (GRCm39) |
N171K |
probably benign |
Het |
| Adam18 |
G |
A |
8: 25,104,859 (GRCm39) |
Q652* |
probably null |
Het |
| Adgrv1 |
T |
C |
13: 81,705,277 (GRCm39) |
E791G |
probably damaging |
Het |
| Aff1 |
C |
T |
5: 103,981,685 (GRCm39) |
S608L |
probably damaging |
Het |
| Amfr |
A |
T |
8: 94,707,018 (GRCm39) |
F432L |
probably damaging |
Het |
| Ankfn1 |
G |
A |
11: 89,332,284 (GRCm39) |
L421F |
possibly damaging |
Het |
| Ankrd31 |
T |
C |
13: 97,014,733 (GRCm39) |
V1334A |
probably benign |
Het |
| Ascc3 |
C |
T |
10: 50,608,858 (GRCm39) |
H1534Y |
possibly damaging |
Het |
| Aste1 |
G |
A |
9: 105,273,880 (GRCm39) |
C40Y |
probably benign |
Het |
| Atf3 |
T |
C |
1: 190,909,510 (GRCm39) |
H53R |
probably benign |
Het |
| Bsn |
C |
A |
9: 107,990,800 (GRCm39) |
V1651F |
probably damaging |
Het |
| Bsn |
A |
T |
9: 107,993,361 (GRCm39) |
L797Q |
probably damaging |
Het |
| Bzw2 |
T |
C |
12: 36,180,131 (GRCm39) |
D32G |
probably damaging |
Het |
| Cacna1e |
A |
T |
1: 154,361,458 (GRCm39) |
M531K |
possibly damaging |
Het |
| Cep120 |
A |
G |
18: 53,851,592 (GRCm39) |
F567L |
possibly damaging |
Het |
| Cit |
T |
C |
5: 116,084,914 (GRCm39) |
I815T |
probably benign |
Het |
| Cnot6l |
G |
T |
5: 96,276,826 (GRCm39) |
Q121K |
probably benign |
Het |
| Col6a3 |
A |
G |
1: 90,743,961 (GRCm39) |
F536L |
probably damaging |
Het |
| Copg2 |
T |
A |
6: 30,793,721 (GRCm39) |
H394L |
possibly damaging |
Het |
| Cst13 |
A |
G |
2: 148,670,165 (GRCm39) |
M112V |
possibly damaging |
Het |
| Cyp2j7 |
G |
T |
4: 96,124,786 (GRCm39) |
N37K |
probably benign |
Het |
| Cyp2u1 |
T |
A |
3: 131,091,449 (GRCm39) |
N357I |
possibly damaging |
Het |
| Dars1 |
T |
C |
1: 128,344,945 (GRCm39) |
T4A |
probably benign |
Het |
| Dclk1 |
G |
T |
3: 55,429,374 (GRCm39) |
C414F |
possibly damaging |
Het |
| Dmbt1 |
A |
T |
7: 130,694,832 (GRCm39) |
Y1009F |
unknown |
Het |
| Ebf4 |
T |
C |
2: 130,148,775 (GRCm39) |
Y117H |
probably damaging |
Het |
| Eif2b4 |
A |
G |
5: 31,348,500 (GRCm39) |
Y196H |
probably benign |
Het |
| Enpp2 |
C |
T |
15: 54,739,080 (GRCm39) |
R401H |
probably damaging |
Het |
| Epo |
T |
C |
5: 137,484,017 (GRCm39) |
|
probably benign |
Het |
| Gli1 |
T |
A |
10: 127,173,359 (GRCm39) |
T100S |
possibly damaging |
Het |
| Gml2 |
T |
A |
15: 74,695,957 (GRCm39) |
F117Y |
probably benign |
Het |
| Hivep1 |
T |
C |
13: 42,335,403 (GRCm39) |
V2314A |
probably benign |
Het |
| Hspb8 |
A |
G |
5: 116,547,487 (GRCm39) |
I165T |
probably damaging |
Het |
| Itgax |
A |
T |
7: 127,732,849 (GRCm39) |
T243S |
probably benign |
Het |
| Itih4 |
G |
T |
14: 30,608,533 (GRCm39) |
L16F |
probably damaging |
Het |
| Kmt5a |
C |
T |
5: 124,578,064 (GRCm39) |
|
probably benign |
Het |
| Lamc1 |
T |
C |
1: 153,115,009 (GRCm39) |
E1089G |
probably benign |
Het |
| Ltbp2 |
G |
A |
12: 84,837,864 (GRCm39) |
P1192L |
probably benign |
Het |
| Mcmbp |
A |
T |
7: 128,317,803 (GRCm39) |
N147K |
probably benign |
Het |
| Mical2 |
C |
T |
7: 111,981,246 (GRCm39) |
L407F |
probably benign |
Het |
| Mybpc2 |
A |
T |
7: 44,158,999 (GRCm39) |
V653D |
probably benign |
Het |
| Myo3b |
G |
A |
2: 70,069,242 (GRCm39) |
V522I |
possibly damaging |
Het |
| Nbr1 |
A |
G |
11: 101,456,590 (GRCm39) |
T156A |
possibly damaging |
Het |
| Neb |
T |
A |
2: 52,039,291 (GRCm39) |
|
probably null |
Het |
| Neb |
T |
A |
2: 52,116,546 (GRCm39) |
Y964F |
|
Het |
| Nr2f2 |
T |
A |
7: 70,007,856 (GRCm39) |
I209F |
probably damaging |
Het |
| Nwd2 |
A |
G |
5: 63,957,740 (GRCm39) |
T357A |
probably damaging |
Het |
| Palld |
C |
T |
8: 61,969,691 (GRCm39) |
R1211H |
unknown |
Het |
| Pcdhb19 |
T |
A |
18: 37,632,299 (GRCm39) |
V698E |
probably damaging |
Het |
| Pcdhga6 |
C |
T |
18: 37,841,570 (GRCm39) |
P430L |
probably damaging |
Het |
| Piezo2 |
A |
G |
18: 63,162,156 (GRCm39) |
L2225S |
possibly damaging |
Het |
| Plekhf1 |
A |
T |
7: 37,921,203 (GRCm39) |
W122R |
probably damaging |
Het |
| Pold3 |
A |
G |
7: 99,732,993 (GRCm39) |
S418P |
possibly damaging |
Het |
| Poldip3 |
T |
C |
15: 83,019,589 (GRCm39) |
N180S |
probably benign |
Het |
| Ppp1r21 |
C |
T |
17: 88,852,815 (GRCm39) |
R65* |
probably null |
Het |
| Ppp1r3d |
A |
T |
2: 178,055,669 (GRCm39) |
V111E |
probably damaging |
Het |
| Prrg4 |
T |
C |
2: 104,669,728 (GRCm39) |
I130V |
probably benign |
Het |
| Psma5 |
A |
T |
3: 108,172,448 (GRCm39) |
T55S |
probably benign |
Het |
| Rbm5 |
C |
A |
9: 107,627,252 (GRCm39) |
A440S |
probably benign |
Het |
| Rdx |
A |
G |
9: 51,980,168 (GRCm39) |
K254E |
possibly damaging |
Het |
| Rere |
A |
C |
4: 150,593,342 (GRCm39) |
Q312P |
unknown |
Het |
| Rest |
T |
C |
5: 77,416,128 (GRCm39) |
V114A |
possibly damaging |
Het |
| Rufy4 |
G |
T |
1: 74,171,879 (GRCm39) |
V201L |
probably benign |
Het |
| Scyl1 |
T |
C |
19: 5,809,023 (GRCm39) |
E727G |
probably benign |
Het |
| Serpinb6b |
T |
A |
13: 33,152,494 (GRCm39) |
M1K |
probably null |
Het |
| Sgsm1 |
C |
A |
5: 113,436,741 (GRCm39) |
V30F |
probably damaging |
Het |
| Skap1 |
A |
G |
11: 96,644,921 (GRCm39) |
D344G |
possibly damaging |
Het |
| Slc26a7 |
T |
C |
4: 14,516,189 (GRCm39) |
T547A |
probably benign |
Het |
| Slc6a3 |
C |
A |
13: 73,692,966 (GRCm39) |
S195R |
probably benign |
Het |
| Sorbs1 |
T |
C |
19: 40,387,048 (GRCm39) |
D6G |
probably damaging |
Het |
| Spock3 |
A |
T |
8: 63,798,746 (GRCm39) |
M253L |
probably damaging |
Het |
| Ssh2 |
A |
G |
11: 77,298,974 (GRCm39) |
Y107C |
possibly damaging |
Het |
| Svil |
T |
C |
18: 5,057,294 (GRCm39) |
S581P |
probably benign |
Het |
| Tbc1d14 |
T |
C |
5: 36,662,472 (GRCm39) |
T553A |
probably benign |
Het |
| Tet3 |
T |
A |
6: 83,380,596 (GRCm39) |
Q524L |
possibly damaging |
Het |
| Uckl1 |
A |
T |
2: 181,211,532 (GRCm39) |
V456E |
probably damaging |
Het |
| Ucp2 |
T |
C |
7: 100,146,040 (GRCm39) |
F4S |
probably benign |
Het |
| Vmn2r77 |
A |
G |
7: 86,444,442 (GRCm39) |
I32V |
probably benign |
Het |
| Vmn2r89 |
T |
A |
14: 51,692,601 (GRCm39) |
Y135N |
probably benign |
Het |
| Vtn |
A |
G |
11: 78,390,587 (GRCm39) |
E82G |
probably benign |
Het |
| Zfp758 |
A |
G |
17: 22,593,925 (GRCm39) |
N137S |
probably benign |
Het |
| Zgpat |
T |
A |
2: 181,021,646 (GRCm39) |
C357* |
probably null |
Het |
|
| Other mutations in Col4a2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00088:Col4a2
|
APN |
8 |
11,493,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00485:Col4a2
|
APN |
8 |
11,489,012 (GRCm39) |
missense |
probably benign |
|
|
IGL00909:Col4a2
|
APN |
8 |
11,498,167 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01574:Col4a2
|
APN |
8 |
11,489,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01914:Col4a2
|
APN |
8 |
11,464,754 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL02147:Col4a2
|
APN |
8 |
11,458,140 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02205:Col4a2
|
APN |
8 |
11,481,305 (GRCm39) |
nonsense |
probably null |
|
|
IGL02423:Col4a2
|
APN |
8 |
11,483,800 (GRCm39) |
missense |
probably benign |
|
|
IGL03131:Col4a2
|
APN |
8 |
11,475,979 (GRCm39) |
missense |
probably benign |
|
|
band
|
UTSW |
8 |
11,498,225 (GRCm39) |
missense |
probably benign |
0.00 |
|
Binder
|
UTSW |
8 |
11,466,070 (GRCm39) |
missense |
probably damaging |
1.00 |
|
G4846:Col4a2
|
UTSW |
8 |
11,458,872 (GRCm39) |
splice site |
probably benign |
|
|
IGL03054:Col4a2
|
UTSW |
8 |
11,498,270 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0087:Col4a2
|
UTSW |
8 |
11,491,296 (GRCm39) |
missense |
probably benign |
|
|
R0124:Col4a2
|
UTSW |
8 |
11,458,871 (GRCm39) |
splice site |
probably benign |
|
|
R0603:Col4a2
|
UTSW |
8 |
11,464,779 (GRCm39) |
missense |
probably benign |
|
|
R0646:Col4a2
|
UTSW |
8 |
11,481,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0970:Col4a2
|
UTSW |
8 |
11,465,438 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1738:Col4a2
|
UTSW |
8 |
11,496,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1746:Col4a2
|
UTSW |
8 |
11,496,020 (GRCm39) |
missense |
probably benign |
0.35 |
|
R1826:Col4a2
|
UTSW |
8 |
11,363,509 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1834:Col4a2
|
UTSW |
8 |
11,452,997 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2016:Col4a2
|
UTSW |
8 |
11,495,086 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2017:Col4a2
|
UTSW |
8 |
11,495,086 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2124:Col4a2
|
UTSW |
8 |
11,466,070 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2137:Col4a2
|
UTSW |
8 |
11,483,749 (GRCm39) |
missense |
probably benign |
|
|
R2207:Col4a2
|
UTSW |
8 |
11,493,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3156:Col4a2
|
UTSW |
8 |
11,363,414 (GRCm39) |
unclassified |
probably benign |
|
|
R4169:Col4a2
|
UTSW |
8 |
11,479,391 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4679:Col4a2
|
UTSW |
8 |
11,481,337 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4705:Col4a2
|
UTSW |
8 |
11,363,504 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4710:Col4a2
|
UTSW |
8 |
11,459,462 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4716:Col4a2
|
UTSW |
8 |
11,452,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4730:Col4a2
|
UTSW |
8 |
11,487,590 (GRCm39) |
missense |
probably benign |
|
|
R4732:Col4a2
|
UTSW |
8 |
11,496,197 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4732:Col4a2
|
UTSW |
8 |
11,464,779 (GRCm39) |
missense |
probably benign |
|
|
R4733:Col4a2
|
UTSW |
8 |
11,496,197 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4733:Col4a2
|
UTSW |
8 |
11,464,779 (GRCm39) |
missense |
probably benign |
|
|
R4834:Col4a2
|
UTSW |
8 |
11,456,836 (GRCm39) |
nonsense |
probably null |
|
|
R4835:Col4a2
|
UTSW |
8 |
11,473,570 (GRCm39) |
nonsense |
probably null |
|
|
R4953:Col4a2
|
UTSW |
8 |
11,479,505 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5078:Col4a2
|
UTSW |
8 |
11,493,936 (GRCm39) |
missense |
probably benign |
|
|
R5204:Col4a2
|
UTSW |
8 |
11,448,651 (GRCm39) |
splice site |
probably null |
|
|
R5221:Col4a2
|
UTSW |
8 |
11,498,225 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5355:Col4a2
|
UTSW |
8 |
11,495,984 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5478:Col4a2
|
UTSW |
8 |
11,448,697 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5492:Col4a2
|
UTSW |
8 |
11,488,608 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5646:Col4a2
|
UTSW |
8 |
11,491,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5857:Col4a2
|
UTSW |
8 |
11,475,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5948:Col4a2
|
UTSW |
8 |
11,470,600 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6329:Col4a2
|
UTSW |
8 |
11,496,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6496:Col4a2
|
UTSW |
8 |
11,452,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6496:Col4a2
|
UTSW |
8 |
11,452,993 (GRCm39) |
nonsense |
probably null |
|
|
R6531:Col4a2
|
UTSW |
8 |
11,458,135 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7185:Col4a2
|
UTSW |
8 |
11,449,739 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7196:Col4a2
|
UTSW |
8 |
11,448,693 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7266:Col4a2
|
UTSW |
8 |
11,475,542 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7308:Col4a2
|
UTSW |
8 |
11,456,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7341:Col4a2
|
UTSW |
8 |
11,448,678 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7394:Col4a2
|
UTSW |
8 |
11,496,184 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7434:Col4a2
|
UTSW |
8 |
11,471,250 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7606:Col4a2
|
UTSW |
8 |
11,493,571 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7646:Col4a2
|
UTSW |
8 |
11,495,086 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7712:Col4a2
|
UTSW |
8 |
11,475,376 (GRCm39) |
missense |
probably benign |
|
|
R7752:Col4a2
|
UTSW |
8 |
11,479,358 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7844:Col4a2
|
UTSW |
8 |
11,475,453 (GRCm39) |
nonsense |
probably null |
|
|
R7901:Col4a2
|
UTSW |
8 |
11,479,358 (GRCm39) |
missense |
probably benign |
0.38 |
|
R8186:Col4a2
|
UTSW |
8 |
11,475,542 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8331:Col4a2
|
UTSW |
8 |
11,463,985 (GRCm39) |
nonsense |
probably null |
|
|
R8389:Col4a2
|
UTSW |
8 |
11,498,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8547:Col4a2
|
UTSW |
8 |
11,479,305 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8927:Col4a2
|
UTSW |
8 |
11,475,543 (GRCm39) |
splice site |
probably null |
|
|
R9051:Col4a2
|
UTSW |
8 |
11,498,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9088:Col4a2
|
UTSW |
8 |
11,493,227 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9221:Col4a2
|
UTSW |
8 |
11,491,943 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9323:Col4a2
|
UTSW |
8 |
11,493,413 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9337:Col4a2
|
UTSW |
8 |
11,479,346 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9697:Col4a2
|
UTSW |
8 |
11,487,628 (GRCm39) |
missense |
probably benign |
0.34 |
|
R9701:Col4a2
|
UTSW |
8 |
11,493,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9729:Col4a2
|
UTSW |
8 |
11,496,157 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9802:Col4a2
|
UTSW |
8 |
11,493,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCATCTTCGTCGGGACAGTTTTC -3'
(R):5'- TAAGCTGTCATCCTAGGGCC -3'
Sequencing Primer
(F):5'- CAGTTTTCTGTTTTCCTCCAAGG -3'
(R):5'- TGTCATCCTAGGGCCCTGTG -3'
|
| Posted On |
2022-04-18 |
Incidental Mutation