Mutagenetix > Incidental Mutation

Incidental Mutation 'R9378:Dnah7a'

709743

Institutional Source

Beutler Lab

Gene Symbol

Dnah7a

Ensembl Gene

ENSMUSG00000096141

Gene Name

dynein, axonemal, heavy chain 7A

Synonyms

Dnahc7, LOC381341, Dnahc7a

MMRRC Submission

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.128) question?

Stock #

R9378 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

53436165-53745943 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 53621776 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Histidine to Glutamine at position 1116 (H1116Q)

Ref Sequence

ENSEMBL: ENSMUSP00000092571 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094964]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000094964
AA Change: H1116Q

PolyPhen 2 Score 0.319 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000092571
Gene: ENSMUSG00000096141
AA Change: H1116Q

Domain	Start	End	E-Value	Type
low complexity region	2	15	N/A	INTRINSIC
coiled coil region	504	537	N/A	INTRINSIC
Pfam:DHC_N2	756	1165	3.1e-149	PFAM
AAA	1320	1459	2.46e-1	SMART
Blast:AAA	1601	1879	1e-87	BLAST
AAA	1968	2116	5.39e-2	SMART
Pfam:AAA_8	2303	2574	6.9e-75	PFAM
Pfam:MT	2586	2936	2.1e-55	PFAM
Pfam:AAA_9	2957	3182	1.3e-98	PFAM
Pfam:Dynein_heavy	3318	4020	2.3e-287	PFAM

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.3%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 88 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2210408I21Rik	A	G	13: 77,471,735 (GRCm39)	K1047E	possibly damaging	Het
Aadacl2fm1	A	G	3: 59,839,110 (GRCm39)	T11A	possibly damaging	Het
Abca14	A	T	7: 119,807,191 (GRCm39)	Y79F	possibly damaging	Het
Abca2	T	A	2: 25,329,094 (GRCm39)	M978K	probably benign	Het
Adamts3	A	T	5: 89,848,269 (GRCm39)	C684*	probably null	Het
Adnp2	T	C	18: 80,172,637 (GRCm39)	T591A	probably benign	Het
Aff4	A	T	11: 53,263,306 (GRCm39)	T109S	probably damaging	Het
Agmo	A	G	12: 37,293,720 (GRCm39)	I48V	probably benign	Het
Appl1	G	A	14: 26,649,784 (GRCm39)	R581*	probably null	Het
Armc9	A	T	1: 86,189,766 (GRCm39)	M714L	probably benign	Het
Atp6v0d2	T	A	4: 19,922,377 (GRCm39)	T41S	probably benign	Het
Bin1	A	T	18: 32,552,921 (GRCm39)	Q182L	probably damaging	Het
Bmp10	A	G	6: 87,410,684 (GRCm39)	D159G	probably benign	Het
Bsn	G	A	9: 107,984,854 (GRCm39)	P295S	possibly damaging	Het
Cbx6	A	G	15: 79,712,606 (GRCm39)	S274P	probably damaging	Het
Cdc20b	A	G	13: 113,192,631 (GRCm39)	K108R	probably benign	Het
Ces1d	T	A	8: 93,912,724 (GRCm39)	N238I	probably damaging	Het
Col7a1	C	T	9: 108,787,708 (GRCm39)	Q663*	probably null	Het
Cpsf3	T	C	12: 21,358,039 (GRCm39)	I517T	possibly damaging	Het
Cyp2a5	C	A	7: 26,539,879 (GRCm39)	T309N	probably damaging	Het
Cyp2d40	A	G	15: 82,645,802 (GRCm39)	F68L	possibly damaging	Het
Cyp7b1	A	T	3: 18,150,837 (GRCm39)	W301R	probably damaging	Het
Dnah6	T	A	6: 73,189,513 (GRCm39)	N45I	probably benign	Het
Dntt	A	G	19: 41,027,356 (GRCm39)	N141S	probably benign	Het
Fbxl13	T	C	5: 21,790,201 (GRCm39)	N281D	probably damaging	Het
Frem2	A	T	3: 53,559,410 (GRCm39)	L1699H	probably damaging	Het
Gabrr3	T	C	16: 59,282,037 (GRCm39)	V464A	possibly damaging	Het
Gdap1	T	A	1: 17,227,353 (GRCm39)	I160N	probably damaging	Het
Hnrnpll	C	A	17: 80,369,291 (GRCm39)	R44L	unknown	Het
Hsp90ab1	T	C	17: 45,881,680 (GRCm39)	E187G	probably damaging	Het
Ighm	T	A	12: 113,386,210 (GRCm39)	T47S		Het
Itgb7	A	C	15: 102,135,831 (GRCm39)		probably null	Het
Kif16b	A	T	2: 142,461,738 (GRCm39)	C1293*	probably null	Het
Klf11	C	T	12: 24,705,043 (GRCm39)	R166C	probably benign	Het
Lca5l	T	A	16: 95,977,212 (GRCm39)	Q198L	probably damaging	Het
Lnx2	A	T	5: 146,961,180 (GRCm39)	M584K	probably benign	Het
Lpp	A	T	16: 24,540,737 (GRCm39)	M1L	probably benign	Het
Lrig3	A	G	10: 125,832,953 (GRCm39)	T276A	probably damaging	Het
Ltbp2	G	A	12: 84,837,864 (GRCm39)	P1192L	probably benign	Het
Megf8	A	T	7: 25,039,840 (GRCm39)		probably null	Het
Myh1	A	C	11: 67,093,259 (GRCm39)	T117P	probably damaging	Het
Neb	C	A	2: 52,134,113 (GRCm39)	R3290L	possibly damaging	Het
Neb	A	C	2: 52,137,304 (GRCm39)	V220G		Het
Nktr	A	T	9: 121,577,264 (GRCm39)	K444I	probably damaging	Het
Nol11	A	T	11: 107,064,505 (GRCm39)	M483K	probably benign	Het
Npy1r	C	A	8: 67,156,861 (GRCm39)	P94T	probably damaging	Het
Nsmaf	T	C	4: 6,440,940 (GRCm39)	T37A	probably benign	Het
Or10ad1b	A	G	15: 98,124,920 (GRCm39)	L204P	possibly damaging	Het
Or2y3	G	A	17: 38,393,056 (GRCm39)	A271V	possibly damaging	Het
Or4c119	T	C	2: 88,987,399 (GRCm39)	N40S	probably damaging	Het
Or51v8	A	T	7: 103,319,389 (GRCm39)	M283K	probably damaging	Het
Or5w14	C	A	2: 87,541,423 (GRCm39)	V276F	possibly damaging	Het
Or8a1b	A	G	9: 37,623,473 (GRCm39)	I34T	probably damaging	Het
Or8b37	G	A	9: 37,958,775 (GRCm39)	V86M	possibly damaging	Het
Palld	C	T	8: 61,969,691 (GRCm39)	R1211H	unknown	Het
Pcdha3	A	G	18: 37,080,284 (GRCm39)	D342G	probably damaging	Het
Pclo	G	A	5: 14,815,877 (GRCm39)	V1266I		Het
Pcnx4	T	C	12: 72,602,664 (GRCm39)	Y309H	probably damaging	Het
Pde8a	C	T	7: 80,982,619 (GRCm39)	T746I	probably damaging	Het
Pdzrn3	T	G	6: 101,127,772 (GRCm39)	K965Q	probably damaging	Het
Phldb1	G	A	9: 44,615,425 (GRCm39)	A225V	probably benign	Het
Pierce1	TCTCTGGGGCAGGCTTAGCCTTGGGCTCCCCCGGCTCCGGCTCCTCTGGGGCAGGCTTAGCCTTGGGCTCCCCCGGCTCCGGCTCCTCTGGGGCGGGCTTAGCCTTGGGCTCCCCCGGCTCCGGCTCCTC	TCTCTGGGGCAGGCTTAGCCTTGGGCTCCCCCGGCTCCGGCTCCTCTGGGGCGGGCTTAGCCTTGGGCTCCCCCGGCTCCGGCTCCTC	2: 28,356,122 (GRCm39)		probably benign	Het
Plat	A	G	8: 23,265,599 (GRCm39)	Y214C	probably damaging	Het
Plppr1	T	A	4: 49,325,627 (GRCm39)	C274*	probably null	Het
Poglut1	A	G	16: 38,347,133 (GRCm39)	F345L	possibly damaging	Het
Ppara	A	T	15: 85,661,837 (GRCm39)	E26V	possibly damaging	Het
Ppcdc	A	T	9: 57,327,571 (GRCm39)	W79R	probably damaging	Het
Prdm1	C	T	10: 44,316,150 (GRCm39)	C662Y	probably damaging	Het
Sgms2	G	A	3: 131,136,011 (GRCm39)		probably benign	Het
Slc31a1	T	A	4: 62,306,843 (GRCm39)	M133K	probably damaging	Het
Smg1	G	A	7: 117,777,998 (GRCm39)	Q1309*	probably null	Het
Sos1	T	C	17: 80,761,239 (GRCm39)	I152M	probably damaging	Het
Stk4	A	T	2: 163,952,136 (GRCm39)		probably benign	Het
Syne1	T	G	10: 5,200,954 (GRCm39)	N3538T	probably damaging	Het
Tbc1d16	A	G	11: 119,099,666 (GRCm39)	F236S	probably damaging	Het
Tgs1	T	A	4: 3,595,475 (GRCm39)	M548K	probably benign	Het
Twf1	G	A	15: 94,483,336 (GRCm39)	T124I	probably damaging	Het
Tyro3	G	A	2: 119,642,648 (GRCm39)	G611R	probably damaging	Het
Unc13b	T	A	4: 43,173,282 (GRCm39)	I1370K	unknown	Het
Usp40	A	G	1: 87,885,032 (GRCm39)	W939R	probably damaging	Het
Vamp8	A	T	6: 72,362,554 (GRCm39)	V82E	probably damaging	Het
Vmn2r17	A	G	5: 109,575,732 (GRCm39)	H201R	possibly damaging	Het
Whrn	T	C	4: 63,350,079 (GRCm39)	H546R	probably benign	Het
Yeats2	T	C	16: 20,033,228 (GRCm39)	V1036A	probably benign	Het
Zfp352	T	G	4: 90,112,575 (GRCm39)	N238K	probably benign	Het
Zfp36l3	TCCAGGGGCGAGGGCAGCCCCAGGAGCAAGGGCCGCCCTAGGAATGAGGGCCGCCCCAGG	TCCAGG	X: 52,776,521 (GRCm39)		probably benign	Het
Zfp462	T	A	4: 55,011,510 (GRCm39)	S1159T	probably benign	Het
Zscan4-ps1	A	T	7: 10,800,192 (GRCm39)	H232Q	probably benign	Het

Other mutations in Dnah7a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00479:Dnah7a	APN	1	53,458,843 (GRCm39)	missense	probably damaging	0.99
IGL00510:Dnah7a	APN	1	53,540,701 (GRCm39)	missense	probably damaging	1.00
IGL00545:Dnah7a	APN	1	53,496,905 (GRCm39)	missense	possibly damaging	0.87
IGL01320:Dnah7a	APN	1	53,473,205 (GRCm39)	missense	probably benign	0.32
IGL01322:Dnah7a	APN	1	53,473,205 (GRCm39)	missense	probably benign	0.32
IGL01357:Dnah7a	APN	1	53,701,540 (GRCm39)	missense	probably benign
IGL01417:Dnah7a	APN	1	53,623,759 (GRCm39)	missense	probably benign	0.01
IGL01508:Dnah7a	APN	1	53,666,231 (GRCm39)	missense	probably benign	0.00
IGL01511:Dnah7a	APN	1	53,458,754 (GRCm39)	missense	probably damaging	1.00
IGL01545:Dnah7a	APN	1	53,557,941 (GRCm39)	missense	probably benign
IGL01575:Dnah7a	APN	1	53,466,979 (GRCm39)	splice site	probably benign
IGL01667:Dnah7a	APN	1	53,586,451 (GRCm39)	missense	probably damaging	1.00
IGL01712:Dnah7a	APN	1	53,462,429 (GRCm39)	missense	probably benign	0.23
IGL01824:Dnah7a	APN	1	53,543,429 (GRCm39)	missense	probably benign
IGL01829:Dnah7a	APN	1	53,657,227 (GRCm39)	missense	possibly damaging	0.64
IGL01861:Dnah7a	APN	1	53,623,608 (GRCm39)	splice site	probably benign
IGL01861:Dnah7a	APN	1	53,679,508 (GRCm39)	missense	probably benign	0.01
IGL01984:Dnah7a	APN	1	53,741,174 (GRCm39)	splice site	probably null
IGL02056:Dnah7a	APN	1	53,543,501 (GRCm39)	missense	probably benign	0.17
IGL02069:Dnah7a	APN	1	53,601,053 (GRCm39)	splice site	probably benign
IGL02072:Dnah7a	APN	1	53,644,986 (GRCm39)	missense	probably damaging	1.00
IGL02110:Dnah7a	APN	1	53,450,739 (GRCm39)	missense	possibly damaging	0.52
IGL02120:Dnah7a	APN	1	53,534,876 (GRCm39)	missense	possibly damaging	0.46
IGL02128:Dnah7a	APN	1	53,476,672 (GRCm39)	missense	probably damaging	1.00
IGL02135:Dnah7a	APN	1	53,662,632 (GRCm39)	missense	probably benign	0.01
IGL02151:Dnah7a	APN	1	53,512,023 (GRCm39)	missense	probably benign	0.08
IGL02156:Dnah7a	APN	1	53,458,882 (GRCm39)	missense	probably benign	0.27
IGL02270:Dnah7a	APN	1	53,512,052 (GRCm39)	missense	possibly damaging	0.93
IGL02282:Dnah7a	APN	1	53,682,669 (GRCm39)	missense	possibly damaging	0.93
IGL02328:Dnah7a	APN	1	53,564,096 (GRCm39)	critical splice donor site	probably null
IGL02370:Dnah7a	APN	1	53,674,556 (GRCm39)	missense	probably benign	0.00
IGL02420:Dnah7a	APN	1	53,725,702 (GRCm39)	missense	probably benign
IGL02458:Dnah7a	APN	1	53,657,487 (GRCm39)	nonsense	probably null
IGL02489:Dnah7a	APN	1	53,686,481 (GRCm39)	missense	possibly damaging	0.94
IGL02554:Dnah7a	APN	1	53,657,205 (GRCm39)	missense	possibly damaging	0.93
IGL02578:Dnah7a	APN	1	53,472,074 (GRCm39)	missense	probably benign	0.00
IGL02646:Dnah7a	APN	1	53,564,194 (GRCm39)	missense	probably damaging	0.99
IGL02675:Dnah7a	APN	1	53,543,183 (GRCm39)	missense	possibly damaging	0.96
IGL02688:Dnah7a	APN	1	53,483,631 (GRCm39)	missense	possibly damaging	0.93
IGL02858:Dnah7a	APN	1	53,512,118 (GRCm39)	splice site	probably benign
IGL02874:Dnah7a	APN	1	53,644,973 (GRCm39)	missense	possibly damaging	0.70
IGL02887:Dnah7a	APN	1	53,561,519 (GRCm39)	missense	possibly damaging	0.46
IGL02894:Dnah7a	APN	1	53,616,487 (GRCm39)	missense	probably benign	0.27
IGL02926:Dnah7a	APN	1	53,535,109 (GRCm39)	missense	possibly damaging	0.64
IGL03113:Dnah7a	APN	1	53,472,163 (GRCm39)	missense	possibly damaging	0.64
IGL03156:Dnah7a	APN	1	53,644,983 (GRCm39)	missense	probably damaging	0.97
IGL03195:Dnah7a	APN	1	53,458,766 (GRCm39)	missense	probably damaging	1.00
IGL03209:Dnah7a	APN	1	53,725,773 (GRCm39)	splice site	probably benign
IGL03214:Dnah7a	APN	1	53,561,368 (GRCm39)	critical splice donor site	probably null
IGL03242:Dnah7a	APN	1	53,659,882 (GRCm39)	missense	probably benign	0.02
IGL03251:Dnah7a	APN	1	53,686,433 (GRCm39)	missense	probably benign
IGL03265:Dnah7a	APN	1	53,568,007 (GRCm39)	missense	probably benign
IGL03277:Dnah7a	APN	1	53,669,481 (GRCm39)	missense	probably benign	0.00
IGL03278:Dnah7a	APN	1	53,536,124 (GRCm39)	missense	probably benign	0.07
IGL03356:Dnah7a	APN	1	53,543,093 (GRCm39)	missense	probably benign	0.01
PIT4378001:Dnah7a	UTSW	1	53,570,362 (GRCm39)	missense	probably damaging	0.99
R0046:Dnah7a	UTSW	1	53,496,033 (GRCm39)	splice site	probably null
R0051:Dnah7a	UTSW	1	53,560,245 (GRCm39)	splice site	probably benign
R0082:Dnah7a	UTSW	1	53,557,867 (GRCm39)	missense	probably damaging	1.00
R0111:Dnah7a	UTSW	1	53,507,843 (GRCm39)	missense	probably benign	0.03
R0122:Dnah7a	UTSW	1	53,436,301 (GRCm39)	missense	probably damaging	1.00
R0245:Dnah7a	UTSW	1	53,540,685 (GRCm39)	missense	probably damaging	1.00
R0278:Dnah7a	UTSW	1	53,543,305 (GRCm39)	missense	probably benign	0.00
R0309:Dnah7a	UTSW	1	53,444,849 (GRCm39)	missense	probably damaging	0.97
R0334:Dnah7a	UTSW	1	53,472,213 (GRCm39)	missense	possibly damaging	0.61
R0392:Dnah7a	UTSW	1	53,543,357 (GRCm39)	missense	probably damaging	0.97
R0452:Dnah7a	UTSW	1	53,644,978 (GRCm39)	missense	probably benign	0.00
R0511:Dnah7a	UTSW	1	53,536,285 (GRCm39)	missense	probably benign
R0576:Dnah7a	UTSW	1	53,675,246 (GRCm39)	missense	probably benign	0.12
R0592:Dnah7a	UTSW	1	53,495,771 (GRCm39)	missense	possibly damaging	0.91
R0628:Dnah7a	UTSW	1	53,536,264 (GRCm39)	missense	probably benign	0.18
R0689:Dnah7a	UTSW	1	53,659,840 (GRCm39)	nonsense	probably null
R0735:Dnah7a	UTSW	1	53,583,670 (GRCm39)	missense	possibly damaging	0.70
R0800:Dnah7a	UTSW	1	53,604,855 (GRCm39)	missense	probably damaging	1.00
R0829:Dnah7a	UTSW	1	53,543,238 (GRCm39)	missense	probably benign	0.07
R0842:Dnah7a	UTSW	1	53,540,833 (GRCm39)	missense	possibly damaging	0.88
R0879:Dnah7a	UTSW	1	53,467,019 (GRCm39)	missense	possibly damaging	0.85
R1331:Dnah7a	UTSW	1	53,507,828 (GRCm39)	missense	probably damaging	0.99
R1418:Dnah7a	UTSW	1	53,686,395 (GRCm39)	splice site	probably benign
R1421:Dnah7a	UTSW	1	53,580,032 (GRCm39)	splice site	probably benign
R1445:Dnah7a	UTSW	1	53,567,956 (GRCm39)	missense	probably benign	0.02
R1473:Dnah7a	UTSW	1	53,535,173 (GRCm39)	missense	probably benign	0.00
R1538:Dnah7a	UTSW	1	53,535,148 (GRCm39)	missense	possibly damaging	0.71
R1742:Dnah7a	UTSW	1	53,495,843 (GRCm39)	missense	probably benign	0.39
R1754:Dnah7a	UTSW	1	53,601,059 (GRCm39)	critical splice donor site	probably null
R1754:Dnah7a	UTSW	1	53,543,344 (GRCm39)	missense	probably benign	0.18
R1773:Dnah7a	UTSW	1	53,472,046 (GRCm39)	splice site	probably null
R1779:Dnah7a	UTSW	1	53,616,382 (GRCm39)	missense	probably benign
R1816:Dnah7a	UTSW	1	53,670,901 (GRCm39)	splice site	probably benign
R1817:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1818:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1819:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1873:Dnah7a	UTSW	1	53,495,691 (GRCm39)	splice site	probably benign
R1875:Dnah7a	UTSW	1	53,495,691 (GRCm39)	splice site	probably benign
R1884:Dnah7a	UTSW	1	53,580,159 (GRCm39)	missense	probably damaging	0.99
R1902:Dnah7a	UTSW	1	53,574,637 (GRCm39)	missense	probably damaging	1.00
R1903:Dnah7a	UTSW	1	53,574,637 (GRCm39)	missense	probably damaging	1.00
R1908:Dnah7a	UTSW	1	53,670,721 (GRCm39)	missense	probably benign
R1959:Dnah7a	UTSW	1	53,724,142 (GRCm39)	missense	probably benign	0.00
R1960:Dnah7a	UTSW	1	53,724,142 (GRCm39)	missense	probably benign	0.00
R1985:Dnah7a	UTSW	1	53,543,093 (GRCm39)	missense	probably benign	0.01
R1992:Dnah7a	UTSW	1	53,621,835 (GRCm39)	missense	possibly damaging	0.91
R2037:Dnah7a	UTSW	1	53,621,741 (GRCm39)	missense	probably benign	0.00
R2074:Dnah7a	UTSW	1	53,496,855 (GRCm39)	missense	probably benign	0.45
R2076:Dnah7a	UTSW	1	53,542,968 (GRCm39)	missense	probably benign	0.01
R2124:Dnah7a	UTSW	1	53,536,101 (GRCm39)	missense	possibly damaging	0.58
R2191:Dnah7a	UTSW	1	53,645,034 (GRCm39)	missense	possibly damaging	0.54
R2211:Dnah7a	UTSW	1	53,518,932 (GRCm39)	missense	probably benign	0.21
R2220:Dnah7a	UTSW	1	53,560,333 (GRCm39)	missense	probably benign
R2355:Dnah7a	UTSW	1	53,621,661 (GRCm39)	missense	probably benign	0.00
R2495:Dnah7a	UTSW	1	53,645,040 (GRCm39)	missense	probably damaging	1.00
R2901:Dnah7a	UTSW	1	53,467,031 (GRCm39)	missense	probably damaging	0.99
R2911:Dnah7a	UTSW	1	53,466,983 (GRCm39)	critical splice donor site	probably null
R2993:Dnah7a	UTSW	1	53,542,713 (GRCm39)	missense	probably damaging	1.00
R3522:Dnah7a	UTSW	1	53,657,275 (GRCm39)	missense	probably damaging	1.00
R3683:Dnah7a	UTSW	1	53,483,675 (GRCm39)	missense	probably benign
R3723:Dnah7a	UTSW	1	53,486,505 (GRCm39)	missense	probably benign	0.04
R3847:Dnah7a	UTSW	1	53,540,815 (GRCm39)	missense	probably benign	0.01
R4002:Dnah7a	UTSW	1	53,670,840 (GRCm39)	missense	probably benign
R4009:Dnah7a	UTSW	1	53,564,164 (GRCm39)	missense	probably damaging	1.00
R4063:Dnah7a	UTSW	1	53,464,376 (GRCm39)	missense	probably benign
R4193:Dnah7a	UTSW	1	53,486,493 (GRCm39)	missense	probably benign	0.00
R4236:Dnah7a	UTSW	1	53,486,524 (GRCm39)	missense	probably benign	0.00
R4399:Dnah7a	UTSW	1	53,557,886 (GRCm39)	missense	probably damaging	1.00
R4469:Dnah7a	UTSW	1	53,483,685 (GRCm39)	missense	probably benign	0.01
R4494:Dnah7a	UTSW	1	53,488,197 (GRCm39)	missense	probably benign	0.01
R4569:Dnah7a	UTSW	1	53,450,818 (GRCm39)	missense	probably benign	0.01
R4609:Dnah7a	UTSW	1	53,495,816 (GRCm39)	missense	possibly damaging	0.80
R4632:Dnah7a	UTSW	1	53,467,110 (GRCm39)	missense	probably damaging	0.97
R4703:Dnah7a	UTSW	1	53,486,476 (GRCm39)	critical splice donor site	probably null
R4781:Dnah7a	UTSW	1	53,464,367 (GRCm39)	missense	probably benign	0.28
R4854:Dnah7a	UTSW	1	53,745,888 (GRCm39)	utr 5 prime	probably benign
R4932:Dnah7a	UTSW	1	53,542,737 (GRCm39)	missense	possibly damaging	0.90
R4976:Dnah7a	UTSW	1	53,737,851 (GRCm39)	missense	probably benign
R5000:Dnah7a	UTSW	1	53,606,201 (GRCm39)	missense	probably damaging	1.00
R5023:Dnah7a	UTSW	1	53,686,407 (GRCm39)	nonsense	probably null
R5026:Dnah7a	UTSW	1	53,701,657 (GRCm39)	missense	probably damaging	0.99
R5050:Dnah7a	UTSW	1	53,536,255 (GRCm39)	missense	probably benign	0.01
R5119:Dnah7a	UTSW	1	53,737,851 (GRCm39)	missense	probably benign
R5151:Dnah7a	UTSW	1	53,659,929 (GRCm39)	missense	probably benign	0.00
R5155:Dnah7a	UTSW	1	53,682,654 (GRCm39)	missense	probably benign	0.01
R5180:Dnah7a	UTSW	1	53,462,446 (GRCm39)	missense	probably damaging	0.97
R5228:Dnah7a	UTSW	1	53,476,768 (GRCm39)	critical splice acceptor site	probably null
R5237:Dnah7a	UTSW	1	53,486,690 (GRCm39)	splice site	probably null
R5267:Dnah7a	UTSW	1	53,518,851 (GRCm39)	missense	probably damaging	1.00
R5334:Dnah7a	UTSW	1	53,542,805 (GRCm39)	missense	probably benign	0.00
R5358:Dnah7a	UTSW	1	53,586,331 (GRCm39)	missense	probably damaging	1.00
R5401:Dnah7a	UTSW	1	53,670,812 (GRCm39)	missense	probably benign	0.01
R5412:Dnah7a	UTSW	1	53,674,503 (GRCm39)	missense	probably benign
R5496:Dnah7a	UTSW	1	53,496,927 (GRCm39)	missense	probably benign
R5531:Dnah7a	UTSW	1	53,458,907 (GRCm39)	missense	possibly damaging	0.50
R5536:Dnah7a	UTSW	1	53,464,412 (GRCm39)	missense	probably benign
R5543:Dnah7a	UTSW	1	53,543,228 (GRCm39)	missense	probably damaging	1.00
R5597:Dnah7a	UTSW	1	53,573,611 (GRCm39)	missense	probably benign	0.00
R5609:Dnah7a	UTSW	1	53,621,753 (GRCm39)	missense	probably benign	0.03
R5643:Dnah7a	UTSW	1	53,444,866 (GRCm39)	missense	probably benign
R5644:Dnah7a	UTSW	1	53,580,138 (GRCm39)	missense	probably benign	0.33
R5689:Dnah7a	UTSW	1	53,444,857 (GRCm39)	missense	possibly damaging	0.87
R5715:Dnah7a	UTSW	1	53,452,937 (GRCm39)	missense	probably damaging	1.00
R5780:Dnah7a	UTSW	1	53,522,478 (GRCm39)	missense	probably benign	0.03
R5893:Dnah7a	UTSW	1	53,496,944 (GRCm39)	missense	possibly damaging	0.66
R5946:Dnah7a	UTSW	1	53,598,467 (GRCm39)	missense	probably damaging	1.00
R5995:Dnah7a	UTSW	1	53,659,829 (GRCm39)	missense	probably benign	0.00
R6102:Dnah7a	UTSW	1	53,598,299 (GRCm39)	missense	probably benign	0.00
R6108:Dnah7a	UTSW	1	53,496,004 (GRCm39)	missense	probably damaging	1.00
R6133:Dnah7a	UTSW	1	53,458,814 (GRCm39)	missense	probably benign	0.05
R6168:Dnah7a	UTSW	1	53,450,727 (GRCm39)	missense	probably damaging	1.00
R6175:Dnah7a	UTSW	1	53,472,181 (GRCm39)	missense	probably damaging	1.00
R6211:Dnah7a	UTSW	1	53,458,795 (GRCm39)	missense	probably damaging	0.99
R6282:Dnah7a	UTSW	1	53,542,760 (GRCm39)	missense	probably damaging	1.00
R6329:Dnah7a	UTSW	1	53,580,273 (GRCm39)	missense	probably damaging	1.00
R6344:Dnah7a	UTSW	1	53,436,349 (GRCm39)	missense	probably benign	0.02
R6530:Dnah7a	UTSW	1	53,542,856 (GRCm39)	missense	probably benign	0.04
R6574:Dnah7a	UTSW	1	53,495,693 (GRCm39)	critical splice donor site	probably null
R6608:Dnah7a	UTSW	1	53,564,277 (GRCm39)	missense	probably benign
R6625:Dnah7a	UTSW	1	53,604,916 (GRCm39)	missense	probably benign	0.05
R6661:Dnah7a	UTSW	1	53,662,609 (GRCm39)	missense	probably benign	0.00
R6681:Dnah7a	UTSW	1	53,560,385 (GRCm39)	critical splice acceptor site	probably null
R6747:Dnah7a	UTSW	1	53,675,221 (GRCm39)	missense	probably benign	0.01
R6774:Dnah7a	UTSW	1	53,737,810 (GRCm39)	missense	probably benign
R6823:Dnah7a	UTSW	1	53,495,863 (GRCm39)	missense	probably benign
R6900:Dnah7a	UTSW	1	53,701,510 (GRCm39)	missense	probably damaging	0.97
R6940:Dnah7a	UTSW	1	53,670,836 (GRCm39)	missense	probably benign	0.09
R6956:Dnah7a	UTSW	1	53,616,446 (GRCm39)	missense	probably benign	0.02
R6978:Dnah7a	UTSW	1	53,701,526 (GRCm39)	missense	probably null
R6988:Dnah7a	UTSW	1	53,621,784 (GRCm39)	missense	possibly damaging	0.62
R7026:Dnah7a	UTSW	1	53,543,448 (GRCm39)	missense	probably benign
R7027:Dnah7a	UTSW	1	53,670,665 (GRCm39)	missense	probably benign	0.01
R7033:Dnah7a	UTSW	1	53,518,820 (GRCm39)	missense	probably damaging	1.00
R7072:Dnah7a	UTSW	1	53,458,912 (GRCm39)	missense	probably benign	0.00
R7096:Dnah7a	UTSW	1	53,522,599 (GRCm39)	missense	possibly damaging	0.90
R7142:Dnah7a	UTSW	1	53,452,927 (GRCm39)	nonsense	probably null
R7144:Dnah7a	UTSW	1	53,737,867 (GRCm39)	splice site	probably null
R7167:Dnah7a	UTSW	1	53,542,935 (GRCm39)	missense	probably benign	0.00
R7182:Dnah7a	UTSW	1	53,659,620 (GRCm39)	splice site	probably null
R7196:Dnah7a	UTSW	1	53,724,000 (GRCm39)	missense	probably benign	0.00
R7206:Dnah7a	UTSW	1	53,737,792 (GRCm39)	nonsense	probably null
R7215:Dnah7a	UTSW	1	53,657,509 (GRCm39)	missense	probably damaging	0.99
R7224:Dnah7a	UTSW	1	53,436,420 (GRCm39)	missense	probably benign	0.00
R7264:Dnah7a	UTSW	1	53,557,973 (GRCm39)	missense	probably benign
R7282:Dnah7a	UTSW	1	53,724,059 (GRCm39)	critical splice acceptor site	probably null
R7365:Dnah7a	UTSW	1	53,536,297 (GRCm39)	missense	probably benign
R7392:Dnah7a	UTSW	1	53,540,820 (GRCm39)	missense	probably benign	0.00
R7454:Dnah7a	UTSW	1	53,557,923 (GRCm39)	missense	probably benign
R7471:Dnah7a	UTSW	1	53,458,858 (GRCm39)	missense	probably damaging	1.00
R7547:Dnah7a	UTSW	1	53,702,996 (GRCm39)	missense	probably benign	0.00
R7554:Dnah7a	UTSW	1	53,567,857 (GRCm39)	missense	possibly damaging	0.87
R7655:Dnah7a	UTSW	1	53,535,164 (GRCm39)	missense	possibly damaging	0.50
R7656:Dnah7a	UTSW	1	53,535,164 (GRCm39)	missense	possibly damaging	0.50
R7666:Dnah7a	UTSW	1	53,586,456 (GRCm39)	missense	probably benign	0.00
R7721:Dnah7a	UTSW	1	53,670,842 (GRCm39)	missense	probably benign
R7813:Dnah7a	UTSW	1	53,657,245 (GRCm39)	missense	probably benign
R7839:Dnah7a	UTSW	1	53,606,334 (GRCm39)	missense	probably benign	0.08
R7959:Dnah7a	UTSW	1	53,682,621 (GRCm39)	missense	probably benign	0.00
R7984:Dnah7a	UTSW	1	53,543,377 (GRCm39)	missense	probably benign	0.01
R7985:Dnah7a	UTSW	1	53,557,886 (GRCm39)	missense	probably damaging	1.00
R8116:Dnah7a	UTSW	1	53,543,049 (GRCm39)	missense	probably benign
R8140:Dnah7a	UTSW	1	53,540,748 (GRCm39)	missense	probably benign	0.02
R8184:Dnah7a	UTSW	1	53,666,194 (GRCm39)	missense	probably benign	0.03
R8339:Dnah7a	UTSW	1	53,724,178 (GRCm39)	missense	probably benign
R8352:Dnah7a	UTSW	1	53,466,986 (GRCm39)	missense	probably null	0.01
R8423:Dnah7a	UTSW	1	53,512,063 (GRCm39)	missense	possibly damaging	0.84
R8428:Dnah7a	UTSW	1	53,512,112 (GRCm39)	missense	probably damaging	0.98
R8432:Dnah7a	UTSW	1	53,657,195 (GRCm39)	missense	possibly damaging	0.46
R8452:Dnah7a	UTSW	1	53,466,986 (GRCm39)	missense	probably null	0.01
R8458:Dnah7a	UTSW	1	53,657,142 (GRCm39)	missense	probably benign	0.01
R8493:Dnah7a	UTSW	1	53,512,067 (GRCm39)	missense	probably damaging	1.00
R8498:Dnah7a	UTSW	1	53,657,139 (GRCm39)	missense	probably benign	0.01
R8502:Dnah7a	UTSW	1	53,679,520 (GRCm39)	missense	probably benign	0.39
R8692:Dnah7a	UTSW	1	53,472,175 (GRCm39)	missense	probably benign	0.00
R8700:Dnah7a	UTSW	1	53,535,088 (GRCm39)	missense	possibly damaging	0.62
R8709:Dnah7a	UTSW	1	53,674,476 (GRCm39)	missense	probably benign
R8856:Dnah7a	UTSW	1	53,462,422 (GRCm39)	missense	probably damaging	1.00
R8875:Dnah7a	UTSW	1	53,682,682 (GRCm39)	missense	probably benign	0.10
R8967:Dnah7a	UTSW	1	53,682,594 (GRCm39)	splice site	probably benign
R8982:Dnah7a	UTSW	1	53,570,301 (GRCm39)	missense	probably benign
R8984:Dnah7a	UTSW	1	53,674,436 (GRCm39)	nonsense	probably null
R8993:Dnah7a	UTSW	1	53,543,262 (GRCm39)	missense	probably damaging	1.00
R9008:Dnah7a	UTSW	1	53,701,501 (GRCm39)	missense	possibly damaging	0.81
R9022:Dnah7a	UTSW	1	53,512,116 (GRCm39)	critical splice acceptor site	probably null
R9028:Dnah7a	UTSW	1	53,560,297 (GRCm39)	missense	probably benign	0.00
R9077:Dnah7a	UTSW	1	53,741,218 (GRCm39)	missense	unknown
R9167:Dnah7a	UTSW	1	53,657,370 (GRCm39)	missense	probably benign	0.00
R9206:Dnah7a	UTSW	1	53,540,757 (GRCm39)	missense	probably benign	0.11
R9226:Dnah7a	UTSW	1	53,560,326 (GRCm39)	missense	possibly damaging	0.93
R9251:Dnah7a	UTSW	1	53,621,671 (GRCm39)	missense	probably damaging	1.00
R9265:Dnah7a	UTSW	1	53,674,505 (GRCm39)	missense	probably benign
R9350:Dnah7a	UTSW	1	53,436,307 (GRCm39)	missense	probably benign	0.19
R9369:Dnah7a	UTSW	1	53,564,222 (GRCm39)	missense	possibly damaging	0.72
R9369:Dnah7a	UTSW	1	53,543,421 (GRCm39)	missense	probably benign
R9372:Dnah7a	UTSW	1	53,543,474 (GRCm39)	missense	probably benign
R9376:Dnah7a	UTSW	1	53,568,058 (GRCm39)	critical splice acceptor site	probably null
R9401:Dnah7a	UTSW	1	53,568,026 (GRCm39)	missense	probably benign	0.01
R9431:Dnah7a	UTSW	1	53,450,812 (GRCm39)	missense	possibly damaging	0.90
R9529:Dnah7a	UTSW	1	53,561,495 (GRCm39)	missense	probably damaging	1.00
R9701:Dnah7a	UTSW	1	53,561,388 (GRCm39)	missense	probably benign	0.03
R9712:Dnah7a	UTSW	1	53,598,299 (GRCm39)	missense	probably benign	0.00
R9799:Dnah7a	UTSW	1	53,557,968 (GRCm39)	missense	probably benign	0.00
R9802:Dnah7a	UTSW	1	53,561,388 (GRCm39)	missense	probably benign	0.03
X0027:Dnah7a	UTSW	1	53,512,089 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnah7a	UTSW	1	53,507,802 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53,522,622 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53,458,858 (GRCm39)	missense	probably damaging	1.00
Z1177:Dnah7a	UTSW	1	53,598,261 (GRCm39)	missense	probably benign	0.21
Z1177:Dnah7a	UTSW	1	53,450,815 (GRCm39)	missense	probably benign	0.08
Z1177:Dnah7a	UTSW	1	53,682,616 (GRCm39)	missense	possibly damaging	0.92

Predicted Primers

PCR Primer
(F):5'- AACCACACATTTCCTCTAAGTTATC -3'
(R):5'- AGATATGCCTACTGCTTTGTACC -3'

Sequencing Primer
(F):5'- AATGTGGGCAGCACTGTC -3'
(R):5'- CCTACTGCTTTGTACCCATTTAAATG -3'

Posted On

2022-04-18