Incidental Mutation 'R9401:Adgrb3'
| ID |
711184 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adgrb3
|
| Ensembl Gene |
ENSMUSG00000033569 |
| Gene Name |
adhesion G protein-coupled receptor B3 |
| Synonyms |
Bai3, A830096D10Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.409)
|
| Stock # |
R9401 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
25106557-25868788 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 25592783 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Phenylalanine
at position 335
(V335F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000035612
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041838]
[ENSMUST00000135518]
[ENSMUST00000146592]
[ENSMUST00000151309]
|
| AlphaFold |
Q80ZF8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000041838
AA Change: V335F
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000035612
Gene: ENSMUSG00000033569
AA Change: V335F
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
TSP1
|
294 |
343 |
2.1e-12 |
SMART |
|
TSP1
|
348 |
398 |
7.97e-13 |
SMART |
|
TSP1
|
403 |
453 |
6.28e-11 |
SMART |
|
TSP1
|
458 |
508 |
1.48e-7 |
SMART |
|
HormR
|
510 |
576 |
4.15e-20 |
SMART |
|
Pfam:DUF3497
|
586 |
810 |
1.7e-52 |
PFAM |
|
GPS
|
815 |
868 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
874 |
1143 |
2.1e-64 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000135518
AA Change: V335F
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000119804
Gene: ENSMUSG00000033569
AA Change: V335F
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
TSP1
|
294 |
343 |
2.1e-12 |
SMART |
|
TSP1
|
348 |
398 |
7.97e-13 |
SMART |
|
TSP1
|
403 |
453 |
6.28e-11 |
SMART |
|
TSP1
|
458 |
508 |
1.48e-7 |
SMART |
|
HormR
|
510 |
576 |
4.15e-20 |
SMART |
|
Pfam:DUF3497
|
586 |
810 |
1.7e-52 |
PFAM |
|
GPS
|
815 |
868 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
874 |
1143 |
2.1e-64 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000146592
AA Change: V128F
PolyPhen 2
Score 0.930 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000116759
Gene: ENSMUSG00000033569
AA Change: V128F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
16 |
N/A |
INTRINSIC |
|
TSP1
|
87 |
136 |
2.1e-12 |
SMART |
|
TSP1
|
141 |
191 |
7.97e-13 |
SMART |
|
TSP1
|
196 |
246 |
6.28e-11 |
SMART |
|
TSP1
|
251 |
301 |
1.48e-7 |
SMART |
|
HormR
|
303 |
369 |
4.15e-20 |
SMART |
|
Pfam:DUF3497
|
379 |
603 |
2.5e-52 |
PFAM |
|
GPS
|
608 |
661 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
667 |
903 |
5.4e-66 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000151309
AA Change: V335F
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000116231
Gene: ENSMUSG00000033569
AA Change: V335F
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
TSP1
|
294 |
343 |
2.1e-12 |
SMART |
|
TSP1
|
348 |
398 |
7.97e-13 |
SMART |
|
TSP1
|
403 |
453 |
6.28e-11 |
SMART |
|
TSP1
|
458 |
508 |
1.48e-7 |
SMART |
|
HormR
|
510 |
576 |
4.15e-20 |
SMART |
|
Pfam:GAIN
|
589 |
794 |
1.1e-44 |
PFAM |
|
GPS
|
815 |
868 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
875 |
1143 |
2.7e-63 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a conditional allele activated in Purkinje cells exhibit impaired motor learning with alterned climbing fiber electrophysiology. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 74 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aars1 |
A |
G |
8: 111,780,785 (GRCm39) |
D850G |
probably benign |
Het |
| Abcc9 |
T |
A |
6: 142,543,836 (GRCm39) |
T1480S |
possibly damaging |
Het |
| Agfg1 |
C |
A |
1: 82,859,958 (GRCm39) |
A275D |
probably benign |
Het |
| Alms1 |
T |
A |
6: 85,655,001 (GRCm39) |
C2713* |
probably null |
Het |
| Atp8a1 |
G |
A |
5: 67,906,492 (GRCm39) |
A474V |
|
Het |
| Baz1a |
C |
A |
12: 54,963,339 (GRCm39) |
S918I |
probably damaging |
Het |
| Bcl2l12 |
G |
T |
7: 44,643,674 (GRCm39) |
T120K |
possibly damaging |
Het |
| Bcl6 |
G |
T |
16: 23,791,107 (GRCm39) |
Q416K |
possibly damaging |
Het |
| Cdhr1 |
T |
A |
14: 36,820,055 (GRCm39) |
I16F |
probably benign |
Het |
| Celsr1 |
G |
T |
15: 85,917,286 (GRCm39) |
S229* |
probably null |
Het |
| Cilp |
T |
C |
9: 65,185,381 (GRCm39) |
V492A |
probably damaging |
Het |
| Crim1 |
CCGC |
CC |
17: 78,658,294 (GRCm39) |
|
probably null |
Het |
| Crppa |
T |
C |
12: 36,552,073 (GRCm39) |
V309A |
probably benign |
Het |
| Ctcfl |
T |
G |
2: 172,947,881 (GRCm39) |
T479P |
probably damaging |
Het |
| Dlx6 |
A |
C |
6: 6,863,581 (GRCm39) |
M68L |
probably benign |
Het |
| Dnah7a |
C |
A |
1: 53,568,026 (GRCm39) |
V1857F |
probably benign |
Het |
| Dpy19l4 |
A |
G |
4: 11,265,806 (GRCm39) |
V714A |
probably benign |
Het |
| Elovl7 |
T |
A |
13: 108,419,188 (GRCm39) |
N273K |
probably benign |
Het |
| Fbxo22 |
A |
G |
9: 55,130,628 (GRCm39) |
K299R |
probably benign |
Het |
| Fig4 |
A |
G |
10: 41,143,733 (GRCm39) |
V242A |
probably benign |
Het |
| Fmo9 |
A |
T |
1: 166,505,189 (GRCm39) |
M68K |
probably damaging |
Het |
| Fry |
T |
A |
5: 150,302,403 (GRCm39) |
Y537N |
probably damaging |
Het |
| Fryl |
C |
T |
5: 73,222,563 (GRCm39) |
W2006* |
probably null |
Het |
| Fzd8 |
T |
A |
18: 9,213,205 (GRCm39) |
C96S |
possibly damaging |
Het |
| Gm40460 |
ACCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAG |
ACCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAG |
7: 141,794,450 (GRCm39) |
|
probably benign |
Het |
| Gspt1 |
T |
C |
16: 11,050,535 (GRCm39) |
D272G |
possibly damaging |
Het |
| Gzmf |
A |
T |
14: 56,448,813 (GRCm39) |
M1K |
probably null |
Het |
| Hipk1 |
T |
C |
3: 103,685,295 (GRCm39) |
T107A |
probably benign |
Het |
| Hsd3b9 |
T |
G |
3: 98,363,819 (GRCm39) |
T9P |
probably damaging |
Het |
| Ighe |
C |
T |
12: 113,233,107 (GRCm39) |
C438Y |
|
Het |
| Igkv4-50 |
T |
A |
6: 69,677,967 (GRCm39) |
R46W |
|
Het |
| Igsf3 |
T |
A |
3: 101,333,075 (GRCm39) |
Y118N |
probably damaging |
Het |
| Itsn1 |
T |
A |
16: 91,612,408 (GRCm39) |
Y266N |
probably damaging |
Het |
| Jph3 |
A |
G |
8: 122,511,854 (GRCm39) |
E614G |
probably damaging |
Het |
| Klk1b8 |
T |
A |
7: 43,603,674 (GRCm39) |
D170E |
probably benign |
Het |
| Ly6e |
A |
T |
15: 74,830,153 (GRCm39) |
K36* |
probably null |
Het |
| Map3k6 |
C |
A |
4: 132,968,467 (GRCm39) |
A23E |
probably damaging |
Het |
| Med13l |
T |
A |
5: 118,883,089 (GRCm39) |
M1316K |
probably benign |
Het |
| Or5c1 |
T |
C |
2: 37,222,293 (GRCm39) |
V178A |
possibly damaging |
Het |
| Or6c76b |
A |
G |
10: 129,693,298 (GRCm39) |
R304G |
probably benign |
Het |
| Or8u3-ps |
A |
T |
2: 85,952,368 (GRCm39) |
I34F |
possibly damaging |
Het |
| Pih1d2 |
T |
A |
9: 50,529,905 (GRCm39) |
C45S |
probably damaging |
Het |
| Pik3r2 |
G |
A |
8: 71,223,737 (GRCm39) |
S318L |
possibly damaging |
Het |
| Pknox1 |
T |
C |
17: 31,802,752 (GRCm39) |
I9T |
probably benign |
Het |
| Pknox2 |
T |
C |
9: 36,835,041 (GRCm39) |
I143V |
probably damaging |
Het |
| Polr1d |
A |
G |
5: 147,015,488 (GRCm39) |
Y57C |
probably damaging |
Het |
| Pum3 |
A |
T |
19: 27,376,336 (GRCm39) |
D527E |
probably benign |
Het |
| Rars2 |
T |
A |
4: 34,654,819 (GRCm39) |
H374Q |
probably damaging |
Het |
| Rassf9 |
G |
A |
10: 102,348,369 (GRCm39) |
|
probably benign |
Het |
| Rbl1 |
T |
A |
2: 157,016,742 (GRCm39) |
H619L |
possibly damaging |
Het |
| Scamp4 |
T |
C |
10: 80,448,238 (GRCm39) |
V153A |
probably benign |
Het |
| Sec23b |
T |
G |
2: 144,420,286 (GRCm39) |
I450S |
probably benign |
Het |
| Slc35b2 |
A |
G |
17: 45,877,910 (GRCm39) |
I297V |
probably benign |
Het |
| Slc4a4 |
C |
T |
5: 89,327,525 (GRCm39) |
T654I |
probably damaging |
Het |
| Slc6a5 |
T |
A |
7: 49,601,185 (GRCm39) |
M662K |
probably damaging |
Het |
| Smarcad1 |
T |
C |
6: 65,071,321 (GRCm39) |
Y589H |
probably benign |
Het |
| Spata31d1e |
T |
C |
13: 59,890,012 (GRCm39) |
T603A |
probably benign |
Het |
| Stab1 |
A |
T |
14: 30,883,069 (GRCm39) |
F374I |
probably benign |
Het |
| Stat5a |
C |
T |
11: 100,756,254 (GRCm39) |
T158M |
possibly damaging |
Het |
| Trpc3 |
A |
T |
3: 36,675,503 (GRCm39) |
Y878* |
probably null |
Het |
| Ubr1 |
T |
A |
2: 120,765,765 (GRCm39) |
T491S |
probably benign |
Het |
| Uggt1 |
C |
T |
1: 36,255,212 (GRCm39) |
|
probably null |
Het |
| Ugt1a6a |
T |
A |
1: 88,066,882 (GRCm39) |
Y229* |
probably null |
Het |
| Vmn1r225 |
G |
A |
17: 20,722,911 (GRCm39) |
W117* |
probably null |
Het |
| Vmn1r225 |
A |
C |
17: 20,722,912 (GRCm39) |
K118Q |
probably damaging |
Het |
| Vmn1r43 |
G |
A |
6: 89,846,877 (GRCm39) |
T203M |
probably damaging |
Het |
| Vmn2r116 |
T |
C |
17: 23,620,566 (GRCm39) |
S767P |
probably damaging |
Het |
| Wdr90 |
AGAC |
AGACGAC |
17: 26,064,750 (GRCm39) |
|
probably benign |
Het |
| Ythdf3 |
C |
T |
3: 16,258,659 (GRCm39) |
P280S |
probably damaging |
Het |
| Zbbx |
A |
G |
3: 75,019,390 (GRCm39) |
S107P |
probably benign |
Het |
| Zdhhc7 |
A |
T |
8: 120,813,425 (GRCm39) |
V128E |
probably benign |
Het |
| Zfp235 |
A |
G |
7: 23,841,551 (GRCm39) |
S657G |
probably damaging |
Het |
| Zfp442 |
T |
A |
2: 150,251,615 (GRCm39) |
I96F |
possibly damaging |
Het |
| Zfp84 |
G |
A |
7: 29,476,297 (GRCm39) |
E330K |
probably damaging |
Het |
|
| Other mutations in Adgrb3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00164:Adgrb3
|
APN |
1 |
25,267,581 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL00507:Adgrb3
|
APN |
1 |
25,113,796 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL00828:Adgrb3
|
APN |
1 |
25,527,200 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01285:Adgrb3
|
APN |
1 |
25,132,868 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL01309:Adgrb3
|
APN |
1 |
25,151,352 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL01540:Adgrb3
|
APN |
1 |
25,151,252 (GRCm39) |
splice site |
probably null |
|
|
IGL01608:Adgrb3
|
APN |
1 |
25,592,855 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01638:Adgrb3
|
APN |
1 |
25,598,832 (GRCm39) |
splice site |
probably benign |
|
|
IGL01657:Adgrb3
|
APN |
1 |
25,865,574 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01666:Adgrb3
|
APN |
1 |
25,499,832 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01712:Adgrb3
|
APN |
1 |
25,865,360 (GRCm39) |
missense |
probably benign |
|
|
IGL01767:Adgrb3
|
APN |
1 |
25,598,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01987:Adgrb3
|
APN |
1 |
25,140,512 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02201:Adgrb3
|
APN |
1 |
25,459,631 (GRCm39) |
splice site |
probably benign |
|
|
IGL02584:Adgrb3
|
APN |
1 |
25,544,065 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02685:Adgrb3
|
APN |
1 |
25,123,323 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02886:Adgrb3
|
APN |
1 |
25,543,991 (GRCm39) |
splice site |
probably null |
|
|
IGL02929:Adgrb3
|
APN |
1 |
25,592,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03153:Adgrb3
|
APN |
1 |
25,570,978 (GRCm39) |
nonsense |
probably null |
|
|
IGL03165:Adgrb3
|
APN |
1 |
25,133,475 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03227:Adgrb3
|
APN |
1 |
25,586,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03392:Adgrb3
|
APN |
1 |
25,543,529 (GRCm39) |
missense |
probably damaging |
0.99 |
|
schwach
|
UTSW |
1 |
25,150,772 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0007:Adgrb3
|
UTSW |
1 |
25,150,772 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0048:Adgrb3
|
UTSW |
1 |
25,140,563 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0048:Adgrb3
|
UTSW |
1 |
25,140,563 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0322:Adgrb3
|
UTSW |
1 |
25,260,829 (GRCm39) |
splice site |
probably benign |
|
|
R0442:Adgrb3
|
UTSW |
1 |
25,435,551 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0563:Adgrb3
|
UTSW |
1 |
25,586,635 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1168:Adgrb3
|
UTSW |
1 |
25,865,280 (GRCm39) |
missense |
probably benign |
|
|
R1252:Adgrb3
|
UTSW |
1 |
25,167,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1264:Adgrb3
|
UTSW |
1 |
25,598,931 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1543:Adgrb3
|
UTSW |
1 |
25,527,169 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1577:Adgrb3
|
UTSW |
1 |
25,133,264 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1581:Adgrb3
|
UTSW |
1 |
25,133,153 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1583:Adgrb3
|
UTSW |
1 |
25,265,912 (GRCm39) |
splice site |
probably null |
|
|
R1653:Adgrb3
|
UTSW |
1 |
25,140,584 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1725:Adgrb3
|
UTSW |
1 |
25,865,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1792:Adgrb3
|
UTSW |
1 |
25,267,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1827:Adgrb3
|
UTSW |
1 |
25,571,658 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1838:Adgrb3
|
UTSW |
1 |
25,123,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1869:Adgrb3
|
UTSW |
1 |
25,865,519 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1971:Adgrb3
|
UTSW |
1 |
25,586,525 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2005:Adgrb3
|
UTSW |
1 |
25,150,799 (GRCm39) |
missense |
probably benign |
0.25 |
|
R2134:Adgrb3
|
UTSW |
1 |
25,133,038 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2142:Adgrb3
|
UTSW |
1 |
25,107,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2268:Adgrb3
|
UTSW |
1 |
25,150,898 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R3740:Adgrb3
|
UTSW |
1 |
25,865,535 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3877:Adgrb3
|
UTSW |
1 |
25,150,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4120:Adgrb3
|
UTSW |
1 |
25,133,388 (GRCm39) |
nonsense |
probably null |
|
|
R4344:Adgrb3
|
UTSW |
1 |
25,865,829 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R4363:Adgrb3
|
UTSW |
1 |
25,151,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4438:Adgrb3
|
UTSW |
1 |
25,870,108 (GRCm39) |
unclassified |
probably benign |
|
|
R4465:Adgrb3
|
UTSW |
1 |
25,133,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4480:Adgrb3
|
UTSW |
1 |
25,150,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4554:Adgrb3
|
UTSW |
1 |
25,123,360 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4557:Adgrb3
|
UTSW |
1 |
25,123,360 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4622:Adgrb3
|
UTSW |
1 |
25,865,569 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4713:Adgrb3
|
UTSW |
1 |
25,586,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4772:Adgrb3
|
UTSW |
1 |
25,570,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4890:Adgrb3
|
UTSW |
1 |
25,260,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5045:Adgrb3
|
UTSW |
1 |
25,113,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5061:Adgrb3
|
UTSW |
1 |
25,107,209 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R5097:Adgrb3
|
UTSW |
1 |
25,865,165 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5227:Adgrb3
|
UTSW |
1 |
25,133,033 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R5241:Adgrb3
|
UTSW |
1 |
25,150,871 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5328:Adgrb3
|
UTSW |
1 |
25,133,356 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5372:Adgrb3
|
UTSW |
1 |
25,167,940 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5703:Adgrb3
|
UTSW |
1 |
25,459,640 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5747:Adgrb3
|
UTSW |
1 |
25,865,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5998:Adgrb3
|
UTSW |
1 |
25,470,582 (GRCm39) |
splice site |
probably null |
|
|
R6006:Adgrb3
|
UTSW |
1 |
25,865,612 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6077:Adgrb3
|
UTSW |
1 |
25,133,081 (GRCm39) |
nonsense |
probably null |
|
|
R6183:Adgrb3
|
UTSW |
1 |
25,133,451 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6190:Adgrb3
|
UTSW |
1 |
25,459,728 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6249:Adgrb3
|
UTSW |
1 |
25,471,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6310:Adgrb3
|
UTSW |
1 |
25,150,799 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6450:Adgrb3
|
UTSW |
1 |
25,459,683 (GRCm39) |
missense |
probably benign |
|
|
R6678:Adgrb3
|
UTSW |
1 |
25,499,891 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6679:Adgrb3
|
UTSW |
1 |
25,170,377 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6685:Adgrb3
|
UTSW |
1 |
25,150,817 (GRCm39) |
nonsense |
probably null |
|
|
R6730:Adgrb3
|
UTSW |
1 |
25,133,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6805:Adgrb3
|
UTSW |
1 |
25,865,253 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6847:Adgrb3
|
UTSW |
1 |
25,133,003 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6929:Adgrb3
|
UTSW |
1 |
25,150,852 (GRCm39) |
nonsense |
probably null |
|
|
R6953:Adgrb3
|
UTSW |
1 |
25,865,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7062:Adgrb3
|
UTSW |
1 |
25,865,166 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7244:Adgrb3
|
UTSW |
1 |
25,170,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7292:Adgrb3
|
UTSW |
1 |
25,570,957 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7325:Adgrb3
|
UTSW |
1 |
25,571,711 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7378:Adgrb3
|
UTSW |
1 |
25,571,000 (GRCm39) |
nonsense |
probably null |
|
|
R7489:Adgrb3
|
UTSW |
1 |
25,586,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7615:Adgrb3
|
UTSW |
1 |
25,137,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7623:Adgrb3
|
UTSW |
1 |
25,586,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7787:Adgrb3
|
UTSW |
1 |
25,471,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7837:Adgrb3
|
UTSW |
1 |
25,167,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8064:Adgrb3
|
UTSW |
1 |
25,459,637 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8152:Adgrb3
|
UTSW |
1 |
25,260,838 (GRCm39) |
splice site |
probably null |
|
|
R8161:Adgrb3
|
UTSW |
1 |
25,133,003 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8225:Adgrb3
|
UTSW |
1 |
25,865,597 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8417:Adgrb3
|
UTSW |
1 |
25,527,134 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8694:Adgrb3
|
UTSW |
1 |
25,865,472 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8742:Adgrb3
|
UTSW |
1 |
25,265,835 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8886:Adgrb3
|
UTSW |
1 |
25,150,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8941:Adgrb3
|
UTSW |
1 |
25,133,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8958:Adgrb3
|
UTSW |
1 |
25,865,190 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8979:Adgrb3
|
UTSW |
1 |
25,527,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9064:Adgrb3
|
UTSW |
1 |
25,570,965 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9252:Adgrb3
|
UTSW |
1 |
25,865,496 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9739:Adgrb3
|
UTSW |
1 |
25,592,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Adgrb3
|
UTSW |
1 |
25,170,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Adgrb3
|
UTSW |
1 |
25,132,995 (GRCm39) |
missense |
probably benign |
0.37 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTATCTAACACCCTGACAGCTCAG -3'
(R):5'- TCAGATTGGTAAGATGCTTACGGG -3'
Sequencing Primer
(F):5'- ACATACAGAGCAAATTATCACAGTTG -3'
(R):5'- TGCTTACGGGATGAATAATCAAGAC -3'
|
| Posted On |
2022-05-16 |
Incidental Mutation