Mutagenetix > Incidental Mutation

Incidental Mutation 'R9405:Dnah17'

711483

Institutional Source

Beutler Lab

Gene Symbol

Dnah17

Ensembl Gene

ENSMUSG00000033987

Gene Name

dynein, axonemal, heavy chain 17

Synonyms

Dnahcl1, LOC382552, 2810003K23Rik, Dnahc17

MMRRC Submission

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R9405 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

117912549-118021460 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 118009737 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 612 (S612P)

Ref Sequence

ENSEMBL: ENSMUSP00000101915 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000084803] [ENSMUST00000106308] [ENSMUST00000132685]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000084803
AA Change: S612P

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000081864
Gene: ENSMUSG00000033987
AA Change: S612P

Domain	Start	End	E-Value	Type
Pfam:DHC_N1	183	766	8.5e-142	PFAM
low complexity region	1015	1028	N/A	INTRINSIC
Pfam:DHC_N2	1260	1673	5.8e-135	PFAM
Pfam:AAA_6	1793	2023	6e-161	PFAM
low complexity region	2092	2104	N/A	INTRINSIC
Pfam:AAA_5	2107	2243	7.8e-13	PFAM
Pfam:AAA_7	2400	2671	1.1e-171	PFAM
Pfam:AAA_8	2748	3015	4.9e-166	PFAM
Pfam:MT	3027	3370	3.4e-214	PFAM
Pfam:AAA_9	3388	3615	2.4e-144	PFAM
Pfam:Dynein_heavy	3742	4452	N/A	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000106308
AA Change: S612P

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000101915
Gene: ENSMUSG00000033987
AA Change: S612P

Domain	Start	End	E-Value	Type
Pfam:DHC_N1	184	764	1.7e-152	PFAM
low complexity region	1015	1028	N/A	INTRINSIC
Pfam:DHC_N2	1262	1671	4.1e-132	PFAM
Pfam:AAA_6	1793	2023	7e-149	PFAM
low complexity region	2092	2104	N/A	INTRINSIC
Pfam:AAA_5	2107	2243	2.5e-11	PFAM
Pfam:AAA_7	2400	2671	4.4e-169	PFAM
Pfam:AAA_8	2748	3015	7.1e-163	PFAM
Pfam:MT	3027	3370	1.1e-210	PFAM
Pfam:AAA_9	3392	3614	1e-84	PFAM
Pfam:Dynein_heavy	3748	4479	3.5e-230	PFAM

Predicted Effect

SMART Domains

Protein: ENSMUSP00000120542
Gene: ENSMUSG00000033987
AA Change: S612P

Domain	Start	End	E-Value	Type
Pfam:DHC_N2	279	688	3.1e-132	PFAM
Pfam:AAA_6	811	1041	5.3e-149	PFAM
low complexity region	1110	1122	N/A	INTRINSIC
Blast:AAA	1123	1354	1e-104	BLAST
Pfam:AAA_7	1452	1671	8.9e-134	PFAM
Pfam:AAA_8	1763	2030	5.4e-163	PFAM
Pfam:MT	2042	2168	6.8e-52	PFAM
Pfam:MT	2163	2412	8.2e-149	PFAM
Pfam:AAA_9	2434	2656	7.9e-85	PFAM
Pfam:Dynein_heavy	2790	3457	2.6e-209	PFAM
Pfam:Dynein_heavy	3460	3569	4.6e-17	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.7%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. DNAH17 is a heavy chain associated with axonemal dynein (Milisav and Affara, 1998 [PubMed 9545504]).[supplied by OMIM, Mar 2008]

Allele List at MGI

Other mutations in this stock

Total: 63 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acaa1b	T	A	9: 118,978,506 (GRCm39)	Q277L	probably damaging	Het
Adamts18	A	G	8: 114,430,030 (GRCm39)	V1135A	probably damaging	Het
Apobr	A	G	7: 126,184,704 (GRCm39)	S72G	possibly damaging	Het
Arl13b	T	A	16: 62,632,260 (GRCm39)	Q214L	possibly damaging	Het
Armt1	AC	A	10: 4,400,848 (GRCm39)		probably null	Het
Asah2	T	G	19: 31,986,045 (GRCm39)	T542P	possibly damaging	Het
Asns	C	T	6: 7,689,283 (GRCm39)	C73Y	probably damaging	Het
Calhm2	T	A	19: 47,124,108 (GRCm39)	T79S	probably benign	Het
Cd300c2	T	G	11: 114,891,587 (GRCm39)	T96P	probably damaging	Het
Copb1	G	A	7: 113,822,458 (GRCm39)	T757I	possibly damaging	Het
Csmd3	T	A	15: 47,539,187 (GRCm39)	T1517S		Het
Ddx60	T	A	8: 62,425,248 (GRCm39)	L679M	probably benign	Het
Dip2b	A	G	15: 100,093,757 (GRCm39)	K1123R	probably benign	Het
Dnah5	T	A	15: 28,272,306 (GRCm39)	C1037S	probably benign	Het
Efcab5	G	A	11: 77,022,934 (GRCm39)	T593I	probably damaging	Het
Ei24	A	T	9: 36,694,137 (GRCm39)	I244N	possibly damaging	Het
Epb41l4a	C	A	18: 33,943,271 (GRCm39)		probably null	Het
Fam83b	A	G	9: 76,398,703 (GRCm39)	M800T	possibly damaging	Het
Fcf1	T	G	12: 85,021,013 (GRCm39)	C98G	probably benign	Het
H2bc3	T	C	13: 23,931,141 (GRCm39)	Y122H	probably benign	Het
Hltf	G	T	3: 20,137,094 (GRCm39)	Q417H	possibly damaging	Het
Hmg20b	T	C	10: 81,185,258 (GRCm39)	S35G	probably benign	Het
Igkv4-57-1	T	G	6: 69,521,525 (GRCm39)	Y59S	probably damaging	Het
Irs2	C	T	8: 11,055,061 (GRCm39)	V1124I	possibly damaging	Het
Kprp	A	G	3: 92,731,560 (GRCm39)	C497R	unknown	Het
Krt15	A	T	11: 100,022,961 (GRCm39)	V418E	probably benign	Het
Lce1e	G	A	3: 92,615,312 (GRCm39)	P12S	unknown	Het
Lsmem1	T	C	12: 40,227,113 (GRCm39)	D124G	probably damaging	Het
Morc3	T	C	16: 93,642,036 (GRCm39)	F85S	probably damaging	Het
Mtnr1b	A	T	9: 15,774,447 (GRCm39)	V204E	possibly damaging	Het
Myo7b	C	T	18: 32,109,356 (GRCm39)	A1172T	probably benign	Het
Nbeal1	T	A	1: 60,349,424 (GRCm39)	I2362N	probably damaging	Het
Nde1	T	G	16: 14,006,255 (GRCm39)	L261R	probably damaging	Het
Neurl1b	A	G	17: 26,658,265 (GRCm39)	D401G	probably benign	Het
Nfkb2	T	C	19: 46,296,839 (GRCm39)	V303A	probably damaging	Het
Nlrc5	C	T	8: 95,199,652 (GRCm39)	P88S	probably damaging	Het
Or10ad1b	T	A	15: 98,124,912 (GRCm39)	I207F	possibly damaging	Het
Or4k36	T	A	2: 111,146,460 (GRCm39)	I212K	possibly damaging	Het
Or6c203	T	A	10: 129,010,165 (GRCm39)	M242L	probably benign	Het
Pde1c	T	A	6: 56,049,199 (GRCm39)	K705*	probably null	Het
Pear1	A	T	3: 87,659,890 (GRCm39)	F699I	probably damaging	Het
Peg10	CCACATCAGGATCCACATCAGGATGCACATCAGCATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAG	CCACATCAGGATCCACATCAGGATGCACATCAG	6: 4,756,398 (GRCm39)		probably benign	Het
Prickle1	A	T	15: 93,400,861 (GRCm39)	L541*	probably null	Het
Prss39	G	A	1: 34,538,344 (GRCm39)	G70S	probably damaging	Het
Prune2	T	G	19: 17,193,708 (GRCm39)	N3065K	probably damaging	Het
Qrfprl	T	A	6: 65,433,078 (GRCm39)	N299K	probably benign	Het
Rdh5	A	C	10: 128,753,937 (GRCm39)	D127E	probably benign	Het
Ryr3	G	A	2: 112,664,612 (GRCm39)	H1580Y	probably damaging	Het
Sash1	G	A	10: 8,637,994 (GRCm39)		probably benign	Het
Scgb3a2	T	A	18: 43,900,129 (GRCm39)	L139Q	possibly damaging	Het
Six1	A	G	12: 73,093,095 (GRCm39)	S36P	probably damaging	Het
Slc30a5	T	C	13: 100,950,416 (GRCm39)	I281V	probably benign	Het
Snai2	T	A	16: 14,524,589 (GRCm39)	Y32N	probably benign	Het
Stat2	T	C	10: 128,114,634 (GRCm39)	S244P	probably damaging	Het
Syne1	A	G	10: 5,152,030 (GRCm39)	I5759T	probably damaging	Het
Tbc1d23	T	C	16: 57,012,985 (GRCm39)	N329S	possibly damaging	Het
Tex2	A	T	11: 106,435,214 (GRCm39)	S737R	unknown	Het
Trav13d-3	G	A	14: 53,270,715 (GRCm39)	R59H	probably benign	Het
Tspan9	C	T	6: 127,944,124 (GRCm39)	A59T	probably benign	Het
Usp53	G	A	3: 122,746,918 (GRCm39)	A349V	probably damaging	Het
Vmn1r188	T	C	13: 22,272,898 (GRCm39)	L284P	probably damaging	Het
Vmn2r85	T	C	10: 130,261,215 (GRCm39)	N374S	probably damaging	Het
Zfp622	A	T	15: 25,985,035 (GRCm39)	I134F	probably damaging	Het

Other mutations in Dnah17

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00231:Dnah17	APN	11	117,979,040 (GRCm39)	missense	possibly damaging	0.81
IGL00531:Dnah17	APN	11	117,933,999 (GRCm39)	missense	probably damaging	0.97
IGL00764:Dnah17	APN	11	117,987,311 (GRCm39)	missense	probably damaging	0.99
IGL00795:Dnah17	APN	11	117,984,460 (GRCm39)	missense	probably benign	0.35
IGL00823:Dnah17	APN	11	117,937,987 (GRCm39)	missense	probably benign	0.22
IGL01145:Dnah17	APN	11	117,937,999 (GRCm39)	missense	possibly damaging	0.63
IGL01433:Dnah17	APN	11	117,940,760 (GRCm39)	missense	probably damaging	1.00
IGL01454:Dnah17	APN	11	117,949,223 (GRCm39)	missense	probably damaging	1.00
IGL01545:Dnah17	APN	11	118,010,394 (GRCm39)	missense	probably damaging	1.00
IGL01548:Dnah17	APN	11	117,989,438 (GRCm39)	missense	probably benign	0.21
IGL01557:Dnah17	APN	11	117,964,512 (GRCm39)	missense	probably damaging	0.98
IGL01632:Dnah17	APN	11	117,924,707 (GRCm39)	missense	probably damaging	1.00
IGL01636:Dnah17	APN	11	117,931,882 (GRCm39)	missense	probably benign	0.03
IGL01672:Dnah17	APN	11	117,932,986 (GRCm39)	missense	probably damaging	0.97
IGL01822:Dnah17	APN	11	117,972,819 (GRCm39)	missense	probably damaging	1.00
IGL01869:Dnah17	APN	11	117,943,502 (GRCm39)	missense	probably benign	0.09
IGL01916:Dnah17	APN	11	118,016,114 (GRCm39)	missense	probably benign	0.00
IGL02131:Dnah17	APN	11	117,963,734 (GRCm39)	missense	probably damaging	1.00
IGL02154:Dnah17	APN	11	118,015,087 (GRCm39)	missense	probably benign	0.01
IGL02220:Dnah17	APN	11	117,963,793 (GRCm39)	nonsense	probably null
IGL02454:Dnah17	APN	11	117,971,593 (GRCm39)	missense	probably damaging	0.98
IGL02458:Dnah17	APN	11	117,927,176 (GRCm39)	missense	probably damaging	1.00
IGL02588:Dnah17	APN	11	117,916,479 (GRCm39)	missense	possibly damaging	0.95
IGL02865:Dnah17	APN	11	117,964,374 (GRCm39)	missense	probably damaging	1.00
IGL02881:Dnah17	APN	11	117,932,944 (GRCm39)	missense	probably damaging	1.00
IGL02952:Dnah17	APN	11	117,979,094 (GRCm39)	missense	probably benign	0.03
IGL03382:Dnah17	APN	11	117,972,769 (GRCm39)	missense	probably damaging	1.00
IGL03389:Dnah17	APN	11	117,985,805 (GRCm39)	missense	probably damaging	1.00
ergos	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
watt	UTSW	11	117,971,592 (GRCm39)	missense	probably damaging	0.96
PIT4280001:Dnah17	UTSW	11	117,989,408 (GRCm39)	missense	possibly damaging	0.85
R0004:Dnah17	UTSW	11	117,950,918 (GRCm39)	missense	possibly damaging	0.90
R0112:Dnah17	UTSW	11	117,965,260 (GRCm39)	missense	possibly damaging	0.82
R0116:Dnah17	UTSW	11	117,949,132 (GRCm39)	missense	probably benign	0.01
R0157:Dnah17	UTSW	11	118,017,997 (GRCm39)	missense	probably benign
R0320:Dnah17	UTSW	11	117,943,500 (GRCm39)	missense	possibly damaging	0.56
R0362:Dnah17	UTSW	11	117,989,365 (GRCm39)	missense	probably benign	0.10
R0382:Dnah17	UTSW	11	118,019,822 (GRCm39)	missense	probably damaging	1.00
R0383:Dnah17	UTSW	11	117,958,373 (GRCm39)	missense	probably benign
R0400:Dnah17	UTSW	11	117,972,904 (GRCm39)	missense	probably damaging	1.00
R0420:Dnah17	UTSW	11	117,930,765 (GRCm39)	missense	probably damaging	1.00
R0483:Dnah17	UTSW	11	117,937,950 (GRCm39)	missense	probably benign
R0533:Dnah17	UTSW	11	118,001,363 (GRCm39)	missense	possibly damaging	0.50
R0562:Dnah17	UTSW	11	117,963,726 (GRCm39)	missense	probably damaging	1.00
R0564:Dnah17	UTSW	11	117,973,807 (GRCm39)	missense	probably damaging	1.00
R0604:Dnah17	UTSW	11	118,012,297 (GRCm39)	missense	probably benign	0.00
R0608:Dnah17	UTSW	11	117,981,575 (GRCm39)	nonsense	probably null
R0614:Dnah17	UTSW	11	117,961,394 (GRCm39)	splice site	probably benign
R0632:Dnah17	UTSW	11	117,958,508 (GRCm39)	splice site	probably benign
R0831:Dnah17	UTSW	11	117,951,097 (GRCm39)	missense	probably damaging	0.99
R0838:Dnah17	UTSW	11	117,950,930 (GRCm39)	missense	probably damaging	1.00
R0879:Dnah17	UTSW	11	117,947,661 (GRCm39)	splice site	probably benign
R1061:Dnah17	UTSW	11	117,943,514 (GRCm39)	missense	possibly damaging	0.51
R1190:Dnah17	UTSW	11	117,933,001 (GRCm39)	missense	probably damaging	1.00
R1293:Dnah17	UTSW	11	118,017,963 (GRCm39)	critical splice donor site	probably null
R1297:Dnah17	UTSW	11	118,012,192 (GRCm39)	splice site	probably benign
R1332:Dnah17	UTSW	11	117,934,041 (GRCm39)	missense	possibly damaging	0.70
R1336:Dnah17	UTSW	11	117,934,041 (GRCm39)	missense	possibly damaging	0.70
R1364:Dnah17	UTSW	11	118,016,432 (GRCm39)	splice site	probably benign
R1418:Dnah17	UTSW	11	117,964,849 (GRCm39)	missense	probably damaging	0.98
R1432:Dnah17	UTSW	11	117,914,153 (GRCm39)	missense	probably damaging	1.00
R1497:Dnah17	UTSW	11	118,005,059 (GRCm39)	missense	probably damaging	1.00
R1500:Dnah17	UTSW	11	117,991,879 (GRCm39)	missense	probably benign
R1506:Dnah17	UTSW	11	118,016,213 (GRCm39)	missense	possibly damaging	0.53
R1512:Dnah17	UTSW	11	117,985,841 (GRCm39)	missense	probably benign
R1567:Dnah17	UTSW	11	118,016,811 (GRCm39)	missense	probably damaging	1.00
R1597:Dnah17	UTSW	11	117,994,324 (GRCm39)	splice site	probably benign
R1665:Dnah17	UTSW	11	118,012,321 (GRCm39)	splice site	probably benign
R1703:Dnah17	UTSW	11	117,917,575 (GRCm39)	missense	probably damaging	1.00
R1716:Dnah17	UTSW	11	117,923,424 (GRCm39)	missense	probably benign	0.00
R1727:Dnah17	UTSW	11	117,987,362 (GRCm39)	nonsense	probably null
R1727:Dnah17	UTSW	11	117,961,315 (GRCm39)	missense	probably damaging	0.98
R1728:Dnah17	UTSW	11	117,960,345 (GRCm39)	missense	possibly damaging	0.76
R1784:Dnah17	UTSW	11	117,960,345 (GRCm39)	missense	possibly damaging	0.76
R1852:Dnah17	UTSW	11	118,012,742 (GRCm39)	missense	probably damaging	0.97
R1869:Dnah17	UTSW	11	117,938,015 (GRCm39)	nonsense	probably null
R1886:Dnah17	UTSW	11	117,998,987 (GRCm39)	missense	possibly damaging	0.62
R1893:Dnah17	UTSW	11	117,957,794 (GRCm39)	missense	probably benign	0.00
R1954:Dnah17	UTSW	11	117,915,557 (GRCm39)	missense	probably damaging	1.00
R1969:Dnah17	UTSW	11	117,995,361 (GRCm39)	missense	probably benign	0.00
R1971:Dnah17	UTSW	11	117,995,361 (GRCm39)	missense	probably benign	0.00
R1975:Dnah17	UTSW	11	117,987,362 (GRCm39)	nonsense	probably null
R1977:Dnah17	UTSW	11	118,003,417 (GRCm39)	missense	possibly damaging	0.52
R2055:Dnah17	UTSW	11	117,958,357 (GRCm39)	missense	probably benign	0.00
R2115:Dnah17	UTSW	11	118,010,628 (GRCm39)	missense	probably benign	0.00
R2132:Dnah17	UTSW	11	117,924,573 (GRCm39)	missense	probably damaging	0.98
R2200:Dnah17	UTSW	11	117,993,235 (GRCm39)	splice site	probably benign
R2277:Dnah17	UTSW	11	117,987,387 (GRCm39)	missense	possibly damaging	0.81
R2279:Dnah17	UTSW	11	117,987,387 (GRCm39)	missense	possibly damaging	0.81
R2400:Dnah17	UTSW	11	118,017,210 (GRCm39)	critical splice acceptor site	probably null
R2402:Dnah17	UTSW	11	118,016,800 (GRCm39)	missense	probably benign	0.10
R2497:Dnah17	UTSW	11	117,977,850 (GRCm39)	splice site	probably null
R2923:Dnah17	UTSW	11	117,984,373 (GRCm39)	missense	probably damaging	1.00
R3121:Dnah17	UTSW	11	117,931,912 (GRCm39)	missense	probably damaging	1.00
R3236:Dnah17	UTSW	11	117,985,680 (GRCm39)	missense	probably benign	0.08
R3237:Dnah17	UTSW	11	117,985,680 (GRCm39)	missense	probably benign	0.08
R3498:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3499:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3746:Dnah17	UTSW	11	117,973,742 (GRCm39)	missense	probably benign	0.00
R3749:Dnah17	UTSW	11	117,973,742 (GRCm39)	missense	probably benign	0.00
R3762:Dnah17	UTSW	11	117,995,352 (GRCm39)	missense	probably benign	0.00
R3826:Dnah17	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
R3828:Dnah17	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
R3829:Dnah17	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
R3877:Dnah17	UTSW	11	117,915,533 (GRCm39)	missense	probably damaging	1.00
R3899:Dnah17	UTSW	11	117,985,634 (GRCm39)	missense	possibly damaging	0.78
R3900:Dnah17	UTSW	11	117,985,634 (GRCm39)	missense	possibly damaging	0.78
R3911:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3913:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3930:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3931:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3969:Dnah17	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
R3970:Dnah17	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
R4056:Dnah17	UTSW	11	117,961,364 (GRCm39)	missense	probably benign	0.05
R4113:Dnah17	UTSW	11	118,003,420 (GRCm39)	missense	possibly damaging	0.50
R4295:Dnah17	UTSW	11	118,009,598 (GRCm39)	missense	probably damaging	1.00
R4324:Dnah17	UTSW	11	117,985,039 (GRCm39)	missense	probably benign	0.01
R4412:Dnah17	UTSW	11	117,964,509 (GRCm39)	missense	probably damaging	1.00
R4413:Dnah17	UTSW	11	117,915,994 (GRCm39)	missense	probably benign	0.00
R4422:Dnah17	UTSW	11	117,972,799 (GRCm39)	missense	possibly damaging	0.91
R4552:Dnah17	UTSW	11	117,943,769 (GRCm39)	missense	possibly damaging	0.79
R4669:Dnah17	UTSW	11	117,965,119 (GRCm39)	missense	probably benign	0.02
R4677:Dnah17	UTSW	11	118,010,640 (GRCm39)	missense	probably damaging	1.00
R4716:Dnah17	UTSW	11	117,964,474 (GRCm39)	missense	probably benign	0.02
R4832:Dnah17	UTSW	11	117,917,606 (GRCm39)	missense	probably damaging	1.00
R4868:Dnah17	UTSW	11	117,999,038 (GRCm39)	missense	probably benign	0.03
R4897:Dnah17	UTSW	11	117,969,419 (GRCm39)	missense	probably damaging	1.00
R4928:Dnah17	UTSW	11	117,918,259 (GRCm39)	missense	probably damaging	1.00
R4937:Dnah17	UTSW	11	117,932,980 (GRCm39)	missense	probably damaging	1.00
R4957:Dnah17	UTSW	11	117,965,124 (GRCm39)	missense	probably benign	0.44
R5008:Dnah17	UTSW	11	118,001,403 (GRCm39)	missense	probably benign	0.01
R5016:Dnah17	UTSW	11	117,971,592 (GRCm39)	missense	probably damaging	0.96
R5027:Dnah17	UTSW	11	117,993,365 (GRCm39)	missense	probably benign	0.01
R5133:Dnah17	UTSW	11	118,007,939 (GRCm39)	missense	probably benign	0.00
R5140:Dnah17	UTSW	11	117,977,771 (GRCm39)	missense	probably damaging	1.00
R5146:Dnah17	UTSW	11	118,005,005 (GRCm39)	missense	probably damaging	0.99
R5151:Dnah17	UTSW	11	117,918,293 (GRCm39)	missense	probably damaging	1.00
R5153:Dnah17	UTSW	11	117,973,800 (GRCm39)	nonsense	probably null
R5192:Dnah17	UTSW	11	117,925,185 (GRCm39)	missense	possibly damaging	0.96
R5315:Dnah17	UTSW	11	118,018,109 (GRCm39)	missense	possibly damaging	0.79
R5317:Dnah17	UTSW	11	118,018,109 (GRCm39)	missense	possibly damaging	0.79
R5335:Dnah17	UTSW	11	118,003,340 (GRCm39)	missense	probably damaging	1.00
R5379:Dnah17	UTSW	11	118,008,029 (GRCm39)	intron	probably benign
R5396:Dnah17	UTSW	11	118,018,108 (GRCm39)	missense	probably benign
R5418:Dnah17	UTSW	11	117,985,810 (GRCm39)	missense	probably benign	0.04
R5534:Dnah17	UTSW	11	117,943,596 (GRCm39)	missense	possibly damaging	0.83
R5539:Dnah17	UTSW	11	117,964,486 (GRCm39)	missense	probably benign	0.03
R5594:Dnah17	UTSW	11	117,934,055 (GRCm39)	splice site	probably null
R5634:Dnah17	UTSW	11	117,943,752 (GRCm39)	splice site	probably null
R5696:Dnah17	UTSW	11	117,991,882 (GRCm39)	missense	probably benign	0.44
R5802:Dnah17	UTSW	11	117,927,272 (GRCm39)	missense	possibly damaging	0.79
R5826:Dnah17	UTSW	11	117,925,193 (GRCm39)	missense	probably damaging	1.00
R5873:Dnah17	UTSW	11	117,947,723 (GRCm39)	missense	probably benign	0.01
R5898:Dnah17	UTSW	11	118,005,039 (GRCm39)	missense	probably benign	0.00
R5934:Dnah17	UTSW	11	117,931,928 (GRCm39)	missense	probably benign
R6030:Dnah17	UTSW	11	117,916,375 (GRCm39)	missense	probably benign	0.32
R6030:Dnah17	UTSW	11	117,916,375 (GRCm39)	missense	probably benign	0.32
R6038:Dnah17	UTSW	11	117,946,715 (GRCm39)	missense	probably benign	0.00
R6038:Dnah17	UTSW	11	117,946,715 (GRCm39)	missense	probably benign	0.00
R6113:Dnah17	UTSW	11	118,017,101 (GRCm39)	missense	probably damaging	1.00
R6117:Dnah17	UTSW	11	118,010,397 (GRCm39)	missense	probably benign	0.00
R6137:Dnah17	UTSW	11	117,916,480 (GRCm39)	missense	probably damaging	1.00
R6173:Dnah17	UTSW	11	117,930,772 (GRCm39)	missense	probably damaging	1.00
R6258:Dnah17	UTSW	11	118,017,150 (GRCm39)	missense	probably damaging	1.00
R6258:Dnah17	UTSW	11	118,017,148 (GRCm39)	missense	probably damaging	1.00
R6258:Dnah17	UTSW	11	118,017,149 (GRCm39)	nonsense	probably null
R6260:Dnah17	UTSW	11	118,017,149 (GRCm39)	nonsense	probably null
R6260:Dnah17	UTSW	11	118,017,150 (GRCm39)	missense	probably damaging	1.00
R6260:Dnah17	UTSW	11	118,017,148 (GRCm39)	missense	probably damaging	1.00
R6278:Dnah17	UTSW	11	118,017,116 (GRCm39)	missense	probably damaging	0.99
R6298:Dnah17	UTSW	11	117,998,987 (GRCm39)	missense	probably benign	0.00
R6300:Dnah17	UTSW	11	117,925,136 (GRCm39)	missense	probably damaging	1.00
R6302:Dnah17	UTSW	11	118,019,981 (GRCm39)	missense	probably benign	0.09
R6363:Dnah17	UTSW	11	118,001,331 (GRCm39)	missense	probably benign
R6381:Dnah17	UTSW	11	118,020,011 (GRCm39)	missense	probably benign	0.08
R6418:Dnah17	UTSW	11	118,020,023 (GRCm39)	missense	probably damaging	0.99
R6660:Dnah17	UTSW	11	117,991,014 (GRCm39)	missense	probably benign
R6803:Dnah17	UTSW	11	118,016,198 (GRCm39)	missense	probably benign	0.00
R6820:Dnah17	UTSW	11	117,959,826 (GRCm39)	missense	probably damaging	0.99
R6885:Dnah17	UTSW	11	117,981,598 (GRCm39)	missense	possibly damaging	0.47
R6921:Dnah17	UTSW	11	117,932,310 (GRCm39)	missense	probably damaging	0.98
R6932:Dnah17	UTSW	11	117,950,905 (GRCm39)	missense	possibly damaging	0.95
R6954:Dnah17	UTSW	11	117,957,258 (GRCm39)	missense	probably damaging	1.00
R7000:Dnah17	UTSW	11	117,916,528 (GRCm39)	critical splice acceptor site	probably null
R7007:Dnah17	UTSW	11	118,009,697 (GRCm39)	missense	possibly damaging	0.92
R7048:Dnah17	UTSW	11	117,936,944 (GRCm39)	missense	possibly damaging	0.80
R7056:Dnah17	UTSW	11	118,016,212 (GRCm39)	missense	probably benign
R7131:Dnah17	UTSW	11	117,970,484 (GRCm39)	missense	probably benign	0.14
R7143:Dnah17	UTSW	11	117,976,956 (GRCm39)	missense	probably damaging	1.00
R7146:Dnah17	UTSW	11	117,972,936 (GRCm39)	missense	probably damaging	0.98
R7147:Dnah17	UTSW	11	117,985,755 (GRCm39)	missense	probably benign	0.31
R7172:Dnah17	UTSW	11	117,931,957 (GRCm39)	nonsense	probably null
R7183:Dnah17	UTSW	11	118,020,014 (GRCm39)	missense	probably benign
R7297:Dnah17	UTSW	11	117,994,182 (GRCm39)	missense	probably damaging	0.98
R7297:Dnah17	UTSW	11	117,946,556 (GRCm39)	critical splice donor site	probably null
R7367:Dnah17	UTSW	11	118,006,022 (GRCm39)	missense	probably benign
R7398:Dnah17	UTSW	11	117,971,550 (GRCm39)	missense	probably damaging	0.96
R7426:Dnah17	UTSW	11	117,981,543 (GRCm39)	missense	probably null	0.79
R7524:Dnah17	UTSW	11	118,012,307 (GRCm39)	missense	probably benign	0.03
R7529:Dnah17	UTSW	11	117,940,692 (GRCm39)	critical splice donor site	probably null
R7615:Dnah17	UTSW	11	118,001,373 (GRCm39)	nonsense	probably null
R7681:Dnah17	UTSW	11	117,916,012 (GRCm39)	missense	probably damaging	1.00
R7702:Dnah17	UTSW	11	118,012,304 (GRCm39)	missense	possibly damaging	0.64
R7702:Dnah17	UTSW	11	117,916,466 (GRCm39)	missense	probably benign	0.00
R7713:Dnah17	UTSW	11	117,915,997 (GRCm39)	missense	probably benign	0.02
R7809:Dnah17	UTSW	11	117,995,462 (GRCm39)	missense	probably benign	0.09
R7842:Dnah17	UTSW	11	117,970,508 (GRCm39)	critical splice acceptor site	probably null
R7935:Dnah17	UTSW	11	118,018,048 (GRCm39)	missense	probably benign	0.20
R7951:Dnah17	UTSW	11	118,009,592 (GRCm39)	missense	possibly damaging	0.64
R8070:Dnah17	UTSW	11	117,915,497 (GRCm39)	missense	probably damaging	0.97
R8098:Dnah17	UTSW	11	117,941,193 (GRCm39)	missense	probably damaging	1.00
R8101:Dnah17	UTSW	11	118,016,744 (GRCm39)	missense	probably benign
R8177:Dnah17	UTSW	11	118,019,753 (GRCm39)	missense	possibly damaging	0.60
R8343:Dnah17	UTSW	11	118,005,021 (GRCm39)	missense	probably benign
R8350:Dnah17	UTSW	11	117,977,873 (GRCm39)	missense	probably damaging	0.98
R8393:Dnah17	UTSW	11	117,947,855 (GRCm39)	missense	probably damaging	1.00
R8401:Dnah17	UTSW	11	117,915,485 (GRCm39)	missense	probably damaging	0.96
R8418:Dnah17	UTSW	11	117,994,284 (GRCm39)	missense	probably benign	0.01
R8450:Dnah17	UTSW	11	117,977,873 (GRCm39)	missense	probably damaging	0.98
R8546:Dnah17	UTSW	11	118,015,101 (GRCm39)	missense	probably benign	0.00
R8697:Dnah17	UTSW	11	117,976,985 (GRCm39)	missense	possibly damaging	0.96
R8710:Dnah17	UTSW	11	117,932,973 (GRCm39)	missense	probably damaging	1.00
R8713:Dnah17	UTSW	11	117,979,028 (GRCm39)	missense	probably damaging	1.00
R8722:Dnah17	UTSW	11	117,961,283 (GRCm39)	nonsense	probably null
R8797:Dnah17	UTSW	11	117,992,201 (GRCm39)	missense	probably benign	0.00
R8953:Dnah17	UTSW	11	118,016,238 (GRCm39)	splice site	probably benign
R8965:Dnah17	UTSW	11	117,915,492 (GRCm39)	missense	probably damaging	1.00
R8976:Dnah17	UTSW	11	117,917,666 (GRCm39)	missense	probably damaging	1.00
R9090:Dnah17	UTSW	11	117,931,870 (GRCm39)	missense	probably damaging	1.00
R9128:Dnah17	UTSW	11	117,937,004 (GRCm39)	missense	possibly damaging	0.76
R9134:Dnah17	UTSW	11	117,978,972 (GRCm39)	missense	probably damaging	1.00
R9245:Dnah17	UTSW	11	118,016,503 (GRCm39)	missense	probably benign	0.02
R9251:Dnah17	UTSW	11	118,012,618 (GRCm39)	missense	probably benign	0.03
R9271:Dnah17	UTSW	11	117,931,870 (GRCm39)	missense	probably damaging	1.00
R9367:Dnah17	UTSW	11	118,012,212 (GRCm39)	missense	possibly damaging	0.93
R9367:Dnah17	UTSW	11	117,987,464 (GRCm39)	missense	possibly damaging	0.95
R9381:Dnah17	UTSW	11	117,914,219 (GRCm39)	missense	probably benign
R9449:Dnah17	UTSW	11	117,987,452 (GRCm39)	missense	probably benign	0.07
R9517:Dnah17	UTSW	11	117,915,440 (GRCm39)	missense	possibly damaging	0.76
R9588:Dnah17	UTSW	11	118,012,783 (GRCm39)	missense	probably benign	0.00
R9629:Dnah17	UTSW	11	117,979,804 (GRCm39)	missense	probably damaging	1.00
R9654:Dnah17	UTSW	11	117,927,156 (GRCm39)	critical splice donor site	probably null
R9655:Dnah17	UTSW	11	117,971,649 (GRCm39)	missense	possibly damaging	0.94
R9662:Dnah17	UTSW	11	117,925,166 (GRCm39)	missense	probably damaging	0.97
R9686:Dnah17	UTSW	11	117,979,048 (GRCm39)	missense	possibly damaging	0.46
R9689:Dnah17	UTSW	11	117,963,731 (GRCm39)	missense	probably damaging	1.00
R9706:Dnah17	UTSW	11	118,017,026 (GRCm39)	missense	probably damaging	1.00
X0058:Dnah17	UTSW	11	117,973,751 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah17	UTSW	11	118,017,992 (GRCm39)	missense	probably benign	0.01
Z1177:Dnah17	UTSW	11	117,977,786 (GRCm39)	missense	probably damaging	1.00
Z1177:Dnah17	UTSW	11	117,969,389 (GRCm39)	missense	possibly damaging	0.91
Z1177:Dnah17	UTSW	11	118,017,968 (GRCm39)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- CGCCTTGCTGAAGTTGACTTG -3'
(R):5'- GTCTTTCCTTCAGTTCACGGGG -3'

Sequencing Primer
(F):5'- CTGAAGTTGACTTGGATGAGGC -3'
(R):5'- CTGTACTGGCAGGCTAAGAACTC -3'

Posted On

2022-05-16