Incidental Mutation 'R9428:Tanc1'
| ID |
712714 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc1
|
| Ensembl Gene |
ENSMUSG00000035168 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 |
| Synonyms |
1200003E16Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9428 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
59442386-59676493 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 59601548 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 143
(L143P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123345
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037526]
[ENSMUST00000112568]
[ENSMUST00000139863]
|
| AlphaFold |
Q0VGY8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000037526
AA Change: L143P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000036003
Gene: ENSMUSG00000035168
AA Change: L143P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112568
AA Change: L143P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108187
Gene: ENSMUSG00000035168
AA Change: L143P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
444 |
N/A |
INTRINSIC |
|
low complexity region
|
448 |
468 |
N/A |
INTRINSIC |
|
ANK
|
886 |
918 |
1.06e3 |
SMART |
|
ANK
|
922 |
953 |
2.43e3 |
SMART |
|
ANK
|
957 |
986 |
1.12e-3 |
SMART |
|
Blast:ANK
|
990 |
1021 |
7e-12 |
BLAST |
|
ANK
|
1030 |
1059 |
1.78e3 |
SMART |
|
ANK
|
1068 |
1097 |
2.34e-1 |
SMART |
|
ANK
|
1101 |
1130 |
3.71e-4 |
SMART |
|
ANK
|
1134 |
1163 |
1.51e-4 |
SMART |
|
ANK
|
1167 |
1196 |
4.89e-4 |
SMART |
|
ANK
|
1200 |
1229 |
3.01e-4 |
SMART |
|
ANK
|
1233 |
1262 |
1.99e2 |
SMART |
|
TPR
|
1279 |
1312 |
7.49e1 |
SMART |
|
TPR
|
1326 |
1359 |
2.35e-1 |
SMART |
|
TPR
|
1360 |
1393 |
6.29e-2 |
SMART |
|
low complexity region
|
1409 |
1425 |
N/A |
INTRINSIC |
|
low complexity region
|
1447 |
1476 |
N/A |
INTRINSIC |
|
low complexity region
|
1649 |
1679 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000139863
AA Change: L143P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000123345
Gene: ENSMUSG00000035168
AA Change: L143P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector exhibit decreased spine density in the CA3 region and impaired spatial memory. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acte1 |
G |
T |
7: 143,434,902 (GRCm39) |
|
probably null |
Het |
| Agmo |
A |
G |
12: 37,455,330 (GRCm39) |
I281M |
probably benign |
Het |
| Ahdc1 |
C |
T |
4: 132,791,773 (GRCm39) |
P1005S |
possibly damaging |
Het |
| Akap12 |
T |
A |
10: 4,303,409 (GRCm39) |
V178D |
probably damaging |
Het |
| Arc |
A |
G |
15: 74,543,063 (GRCm39) |
S387P |
probably benign |
Het |
| Arhgap11a |
C |
T |
2: 113,667,279 (GRCm39) |
V423I |
probably benign |
Het |
| Arhgap44 |
A |
G |
11: 64,899,168 (GRCm39) |
S670P |
probably damaging |
Het |
| C4b |
G |
A |
17: 34,949,885 (GRCm39) |
T1433M |
possibly damaging |
Het |
| C4bp |
A |
T |
1: 130,581,094 (GRCm39) |
F138L |
probably benign |
Het |
| Carmil1 |
A |
T |
13: 24,295,834 (GRCm39) |
C393* |
probably null |
Het |
| Cblif |
A |
G |
19: 11,735,102 (GRCm39) |
T241A |
probably benign |
Het |
| Celsr1 |
A |
T |
15: 85,815,549 (GRCm39) |
V1822E |
possibly damaging |
Het |
| Chgb |
C |
G |
2: 132,635,154 (GRCm39) |
S365R |
probably damaging |
Het |
| Cnih3 |
T |
C |
1: 181,180,857 (GRCm39) |
|
probably benign |
Het |
| Dcaf1 |
T |
A |
9: 106,735,528 (GRCm39) |
D825E |
possibly damaging |
Het |
| Dlx3 |
T |
C |
11: 95,011,430 (GRCm39) |
Y95H |
probably benign |
Het |
| Dmbt1 |
A |
T |
7: 130,668,208 (GRCm39) |
E488V |
unknown |
Het |
| Espnl |
A |
G |
1: 91,273,595 (GRCm39) |
Y985C |
probably damaging |
Het |
| Frmpd2 |
T |
C |
14: 33,272,010 (GRCm39) |
V1048A |
probably damaging |
Het |
| Fxn |
A |
T |
19: 24,249,787 (GRCm39) |
L100Q |
probably damaging |
Het |
| Gapvd1 |
T |
A |
2: 34,607,318 (GRCm39) |
D560V |
probably damaging |
Het |
| Gm4924 |
T |
A |
10: 82,213,490 (GRCm39) |
H429Q |
unknown |
Het |
| Gpr158 |
T |
C |
2: 21,787,972 (GRCm39) |
F538L |
probably benign |
Het |
| Itpr1 |
T |
A |
6: 108,378,308 (GRCm39) |
M1278K |
possibly damaging |
Het |
| Ivd |
T |
A |
2: 118,708,369 (GRCm39) |
V361E |
probably damaging |
Het |
| Kcnh6 |
T |
C |
11: 105,899,821 (GRCm39) |
L30P |
probably damaging |
Het |
| Lipo4 |
C |
T |
19: 33,495,074 (GRCm39) |
V35I |
probably benign |
Het |
| Lmo7 |
A |
G |
14: 102,155,076 (GRCm39) |
D1200G |
probably damaging |
Het |
| Med1 |
T |
A |
11: 98,080,049 (GRCm39) |
R31* |
probably null |
Het |
| Mill2 |
A |
T |
7: 18,573,950 (GRCm39) |
R12* |
probably null |
Het |
| Mphosph8 |
A |
G |
14: 56,934,114 (GRCm39) |
|
probably null |
Het |
| Mtfr2 |
T |
A |
10: 20,233,039 (GRCm39) |
S203T |
possibly damaging |
Het |
| Muc5ac |
A |
C |
7: 141,362,559 (GRCm39) |
T1957P |
unknown |
Het |
| Mxi1 |
C |
A |
19: 53,299,213 (GRCm39) |
P28Q |
probably benign |
Het |
| Mycbpap |
T |
C |
11: 94,393,995 (GRCm39) |
D367G |
probably damaging |
Het |
| Nav3 |
T |
C |
10: 109,605,176 (GRCm39) |
T966A |
probably benign |
Het |
| Nbea |
AC |
A |
3: 55,998,393 (GRCm39) |
|
probably null |
Het |
| Ndst2 |
A |
T |
14: 20,775,470 (GRCm39) |
F673L |
possibly damaging |
Het |
| Ndst3 |
T |
A |
3: 123,340,518 (GRCm39) |
I767F |
probably benign |
Het |
| Nell1 |
A |
T |
7: 50,503,683 (GRCm39) |
D696V |
probably damaging |
Het |
| Nol9 |
A |
T |
4: 152,124,109 (GRCm39) |
T100S |
probably benign |
Het |
| Nr4a1 |
T |
C |
15: 101,168,245 (GRCm39) |
S94P |
probably damaging |
Het |
| Nrdc |
T |
C |
4: 108,858,121 (GRCm39) |
I31T |
probably damaging |
Het |
| Oas2 |
T |
A |
5: 120,887,576 (GRCm39) |
D88V |
probably damaging |
Het |
| Or8w1 |
T |
C |
2: 87,465,774 (GRCm39) |
I106V |
probably benign |
Het |
| Pex6 |
A |
G |
17: 47,022,991 (GRCm39) |
H189R |
probably benign |
Het |
| Pgap1 |
A |
G |
1: 54,575,206 (GRCm39) |
S239P |
probably damaging |
Het |
| Pheta1 |
C |
T |
5: 121,991,147 (GRCm39) |
P170S |
possibly damaging |
Het |
| Plec |
A |
G |
15: 76,067,721 (GRCm39) |
|
probably null |
Het |
| Plekhg5 |
T |
C |
4: 152,192,780 (GRCm39) |
V582A |
probably benign |
Het |
| Plekhh2 |
G |
T |
17: 84,873,841 (GRCm39) |
E375D |
probably benign |
Het |
| Pramel55 |
G |
T |
5: 95,949,545 (GRCm39) |
R97S |
probably damaging |
Het |
| Prp2rt |
A |
G |
13: 97,235,724 (GRCm39) |
S8P |
probably benign |
Het |
| Psmd4 |
G |
A |
3: 94,940,767 (GRCm39) |
T332I |
probably benign |
Het |
| Ptprc |
T |
A |
1: 138,041,485 (GRCm39) |
T76S |
probably benign |
Het |
| Rab44 |
A |
T |
17: 29,358,315 (GRCm39) |
I168L |
|
Het |
| Ros1 |
T |
C |
10: 51,958,061 (GRCm39) |
T1872A |
probably benign |
Het |
| Scgb1b24 |
A |
T |
7: 33,443,493 (GRCm39) |
K51* |
probably null |
Het |
| Scube2 |
A |
T |
7: 109,428,345 (GRCm39) |
D509E |
probably benign |
Het |
| Sgo2b |
A |
T |
8: 64,393,067 (GRCm39) |
S123R |
probably damaging |
Het |
| Smc3 |
G |
C |
19: 53,617,150 (GRCm39) |
R521P |
possibly damaging |
Het |
| Socs4 |
G |
A |
14: 47,528,034 (GRCm39) |
R323H |
probably damaging |
Het |
| Socs5 |
T |
A |
17: 87,441,067 (GRCm39) |
D2E |
probably benign |
Het |
| Sra1 |
A |
G |
18: 36,810,299 (GRCm39) |
V121A |
probably damaging |
Het |
| Stimate |
T |
C |
14: 30,594,645 (GRCm39) |
S253P |
probably benign |
Het |
| Tcerg1l |
A |
T |
7: 137,811,490 (GRCm39) |
F568Y |
probably damaging |
Het |
| Trpm7 |
T |
C |
2: 126,671,140 (GRCm39) |
E614G |
probably damaging |
Het |
| Tuba4a |
G |
T |
1: 75,192,686 (GRCm39) |
H337Q |
|
Het |
| Tubgcp6 |
G |
A |
15: 88,985,100 (GRCm39) |
H1663Y |
probably damaging |
Het |
| Ush2a |
A |
G |
1: 188,175,316 (GRCm39) |
Y1138C |
probably damaging |
Het |
| Vmn1r18 |
A |
T |
6: 57,367,535 (GRCm39) |
N6K |
possibly damaging |
Het |
| Vmn1r213 |
G |
A |
13: 23,195,944 (GRCm39) |
A176T |
|
Het |
| Vmn1r215 |
A |
T |
13: 23,260,749 (GRCm39) |
H263L |
probably benign |
Het |
| Vmn2r51 |
CGGCCAATAGAAGAAACTTTTACCTTCAAGCAGTGAGAACTGGC |
CGGC |
7: 9,833,712 (GRCm39) |
|
probably benign |
Het |
| Wdhd1 |
A |
C |
14: 47,489,427 (GRCm39) |
L702* |
probably null |
Het |
| Zc3h12a |
T |
C |
4: 125,020,558 (GRCm39) |
E95G |
probably benign |
Het |
|
| Other mutations in Tanc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Tanc1
|
APN |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL00484:Tanc1
|
APN |
2 |
59,623,520 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00688:Tanc1
|
APN |
2 |
59,645,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00765:Tanc1
|
APN |
2 |
59,636,645 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01576:Tanc1
|
APN |
2 |
59,628,079 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01590:Tanc1
|
APN |
2 |
59,615,817 (GRCm39) |
missense |
probably benign |
|
|
IGL02016:Tanc1
|
APN |
2 |
59,673,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02373:Tanc1
|
APN |
2 |
59,626,372 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02539:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02541:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02543:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02559:Tanc1
|
APN |
2 |
59,554,998 (GRCm39) |
splice site |
probably benign |
|
|
IGL02626:Tanc1
|
APN |
2 |
59,630,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02669:Tanc1
|
APN |
2 |
59,630,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02902:Tanc1
|
APN |
2 |
59,623,431 (GRCm39) |
splice site |
probably benign |
|
|
Oreja
|
UTSW |
2 |
59,622,148 (GRCm39) |
synonymous |
silent |
|
|
R0178:Tanc1
|
UTSW |
2 |
59,665,791 (GRCm39) |
nonsense |
probably null |
|
|
R0347:Tanc1
|
UTSW |
2 |
59,673,335 (GRCm39) |
missense |
probably benign |
|
|
R0570:Tanc1
|
UTSW |
2 |
59,626,382 (GRCm39) |
splice site |
probably benign |
|
|
R0660:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0664:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0898:Tanc1
|
UTSW |
2 |
59,621,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1333:Tanc1
|
UTSW |
2 |
59,673,835 (GRCm39) |
missense |
probably benign |
|
|
R1575:Tanc1
|
UTSW |
2 |
59,621,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1608:Tanc1
|
UTSW |
2 |
59,628,038 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1616:Tanc1
|
UTSW |
2 |
59,615,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1703:Tanc1
|
UTSW |
2 |
59,673,365 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1727:Tanc1
|
UTSW |
2 |
59,621,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1809:Tanc1
|
UTSW |
2 |
59,630,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1812:Tanc1
|
UTSW |
2 |
59,622,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1925:Tanc1
|
UTSW |
2 |
59,555,095 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1951:Tanc1
|
UTSW |
2 |
59,622,156 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Tanc1
|
UTSW |
2 |
59,674,177 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2228:Tanc1
|
UTSW |
2 |
59,555,068 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2267:Tanc1
|
UTSW |
2 |
59,667,563 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4191:Tanc1
|
UTSW |
2 |
59,669,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4476:Tanc1
|
UTSW |
2 |
59,672,340 (GRCm39) |
splice site |
probably null |
|
|
R4632:Tanc1
|
UTSW |
2 |
59,626,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Tanc1
|
UTSW |
2 |
59,529,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4982:Tanc1
|
UTSW |
2 |
59,630,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5338:Tanc1
|
UTSW |
2 |
59,626,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5657:Tanc1
|
UTSW |
2 |
59,665,051 (GRCm39) |
splice site |
probably null |
|
|
R5672:Tanc1
|
UTSW |
2 |
59,602,697 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5703:Tanc1
|
UTSW |
2 |
59,626,341 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5707:Tanc1
|
UTSW |
2 |
59,588,874 (GRCm39) |
missense |
probably benign |
|
|
R5778:Tanc1
|
UTSW |
2 |
59,529,691 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5795:Tanc1
|
UTSW |
2 |
59,637,926 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5831:Tanc1
|
UTSW |
2 |
59,615,685 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5849:Tanc1
|
UTSW |
2 |
59,630,248 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5912:Tanc1
|
UTSW |
2 |
59,622,030 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5944:Tanc1
|
UTSW |
2 |
59,667,564 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6057:Tanc1
|
UTSW |
2 |
59,647,837 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6142:Tanc1
|
UTSW |
2 |
59,663,566 (GRCm39) |
nonsense |
probably null |
|
|
R6179:Tanc1
|
UTSW |
2 |
59,673,320 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6185:Tanc1
|
UTSW |
2 |
59,621,929 (GRCm39) |
splice site |
probably null |
|
|
R6192:Tanc1
|
UTSW |
2 |
59,669,305 (GRCm39) |
splice site |
probably null |
|
|
R6196:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6197:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6230:Tanc1
|
UTSW |
2 |
59,672,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6275:Tanc1
|
UTSW |
2 |
59,673,854 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6415:Tanc1
|
UTSW |
2 |
59,667,458 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6480:Tanc1
|
UTSW |
2 |
59,637,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6578:Tanc1
|
UTSW |
2 |
59,626,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6786:Tanc1
|
UTSW |
2 |
59,622,150 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7006:Tanc1
|
UTSW |
2 |
59,626,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7133:Tanc1
|
UTSW |
2 |
59,627,953 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7381:Tanc1
|
UTSW |
2 |
59,615,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7422:Tanc1
|
UTSW |
2 |
59,636,688 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8392:Tanc1
|
UTSW |
2 |
59,636,651 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8692:Tanc1
|
UTSW |
2 |
59,673,989 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8730:Tanc1
|
UTSW |
2 |
59,601,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8731:Tanc1
|
UTSW |
2 |
59,673,596 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8813:Tanc1
|
UTSW |
2 |
59,630,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8815:Tanc1
|
UTSW |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8933:Tanc1
|
UTSW |
2 |
59,615,800 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9015:Tanc1
|
UTSW |
2 |
59,622,224 (GRCm39) |
missense |
probably benign |
|
|
R9042:Tanc1
|
UTSW |
2 |
59,673,766 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9154:Tanc1
|
UTSW |
2 |
59,630,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9269:Tanc1
|
UTSW |
2 |
59,630,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9283:Tanc1
|
UTSW |
2 |
59,630,174 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9380:Tanc1
|
UTSW |
2 |
59,665,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9422:Tanc1
|
UTSW |
2 |
59,637,933 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9694:Tanc1
|
UTSW |
2 |
59,626,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF028:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
RF049:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
X0063:Tanc1
|
UTSW |
2 |
59,674,324 (GRCm39) |
nonsense |
probably null |
|
|
X0064:Tanc1
|
UTSW |
2 |
59,674,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tanc1
|
UTSW |
2 |
59,602,873 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,622,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,621,231 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGCATCGTCAAACTTGGTGC -3'
(R):5'- GCTGAGACCCAGAAACTAACTG -3'
Sequencing Primer
(F):5'- CAAACTTGGTGCATCTTATAAGGGG -3'
(R):5'- TTAAATTTCAAAACACAAGTGCCCAG -3'
|
| Posted On |
2022-05-16 |
Incidental Mutation