Incidental Mutation 'R9428:Carmil1'
| ID |
712757 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Carmil1
|
| Ensembl Gene |
ENSMUSG00000021338 |
| Gene Name |
capping protein regulator and myosin 1 linker 1 |
| Synonyms |
Carmil, Lrrc16a, 1110037D04Rik, Lrrc16 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9428 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
24196327-24464778 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
A to T
at 24295834 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Stop codon
at position 393
(C393*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000072662
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072889]
[ENSMUST00000110398]
[ENSMUST00000125901]
|
| AlphaFold |
Q6EDY6 |
| PDB Structure |
Solution structure of the CARMIL CAH3a/b domain bound to capping protein (CP) [SOLUTION NMR]
Crystal structure of Actin Capping Protein in complex with the Cp-binding motif derived from CARMIL [X-RAY DIFFRACTION]
Crystal structure of Actin capping protein in complex with CARMIL fragment [X-RAY DIFFRACTION]
Crystal Structure of mouse CARMIL residues 1-668 [X-RAY DIFFRACTION]
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000072889
AA Change: C393*
|
| SMART Domains |
Protein: ENSMUSP00000072662
Gene: ENSMUSG00000021338
AA Change: C393*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
37 |
N/A |
INTRINSIC |
|
LRR
|
245 |
272 |
2.42e1 |
SMART |
|
LRR
|
275 |
302 |
1.04e1 |
SMART |
|
LRR
|
304 |
331 |
3.1e0 |
SMART |
|
LRR
|
336 |
363 |
5.66e1 |
SMART |
|
Blast:LRR
|
423 |
450 |
9e-8 |
BLAST |
|
Blast:LRR
|
451 |
484 |
7e-9 |
BLAST |
|
LRR
|
574 |
601 |
8.81e-2 |
SMART |
|
Blast:LRR
|
602 |
629 |
6e-10 |
BLAST |
|
low complexity region
|
745 |
758 |
N/A |
INTRINSIC |
|
Pfam:CARMIL_C
|
790 |
1083 |
1.1e-101 |
PFAM |
|
low complexity region
|
1131 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1253 |
1268 |
N/A |
INTRINSIC |
|
low complexity region
|
1287 |
1296 |
N/A |
INTRINSIC |
|
low complexity region
|
1317 |
1332 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000110398
AA Change: C393*
|
| SMART Domains |
Protein: ENSMUSP00000106028
Gene: ENSMUSG00000021338
AA Change: C393*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
37 |
N/A |
INTRINSIC |
|
LRR
|
245 |
272 |
2.42e1 |
SMART |
|
LRR
|
275 |
302 |
1.04e1 |
SMART |
|
LRR
|
304 |
331 |
3.1e0 |
SMART |
|
LRR
|
336 |
363 |
5.66e1 |
SMART |
|
Blast:LRR
|
423 |
450 |
9e-8 |
BLAST |
|
LRR
|
451 |
480 |
3.15e1 |
SMART |
|
Pfam:LRR_6
|
481 |
507 |
1.9e-2 |
PFAM |
|
LRR
|
570 |
597 |
8.81e-2 |
SMART |
|
Blast:LRR
|
598 |
625 |
6e-10 |
BLAST |
|
low complexity region
|
741 |
754 |
N/A |
INTRINSIC |
|
low complexity region
|
879 |
888 |
N/A |
INTRINSIC |
|
PDB:3LK3|T
|
964 |
1076 |
1e-56 |
PDB |
|
low complexity region
|
1127 |
1143 |
N/A |
INTRINSIC |
|
low complexity region
|
1241 |
1247 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1264 |
N/A |
INTRINSIC |
|
low complexity region
|
1283 |
1292 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1325 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125901
|
| SMART Domains |
Protein: ENSMUSP00000126522
Gene: ENSMUSG00000021338
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:LRR
|
13 |
40 |
5e-8 |
BLAST |
|
Blast:LRR
|
41 |
74 |
4e-9 |
BLAST |
|
Pfam:LRR_6
|
75 |
101 |
4.4e-2 |
PFAM |
|
Pfam:LRR_6
|
164 |
187 |
1.6e-3 |
PFAM |
|
Blast:LRR
|
192 |
219 |
7e-10 |
BLAST |
|
low complexity region
|
335 |
348 |
N/A |
INTRINSIC |
|
low complexity region
|
473 |
482 |
N/A |
INTRINSIC |
|
PDB:3LK3|T
|
564 |
676 |
4e-57 |
PDB |
|
low complexity region
|
727 |
743 |
N/A |
INTRINSIC |
|
low complexity region
|
841 |
847 |
N/A |
INTRINSIC |
|
low complexity region
|
849 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
883 |
892 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
925 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: No abnormal phenotype was observed in a high-throughput screen, nor in a pathology assessment. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acte1 |
G |
T |
7: 143,434,902 (GRCm39) |
|
probably null |
Het |
| Agmo |
A |
G |
12: 37,455,330 (GRCm39) |
I281M |
probably benign |
Het |
| Ahdc1 |
C |
T |
4: 132,791,773 (GRCm39) |
P1005S |
possibly damaging |
Het |
| Akap12 |
T |
A |
10: 4,303,409 (GRCm39) |
V178D |
probably damaging |
Het |
| Arc |
A |
G |
15: 74,543,063 (GRCm39) |
S387P |
probably benign |
Het |
| Arhgap11a |
C |
T |
2: 113,667,279 (GRCm39) |
V423I |
probably benign |
Het |
| Arhgap44 |
A |
G |
11: 64,899,168 (GRCm39) |
S670P |
probably damaging |
Het |
| C4b |
G |
A |
17: 34,949,885 (GRCm39) |
T1433M |
possibly damaging |
Het |
| C4bp |
A |
T |
1: 130,581,094 (GRCm39) |
F138L |
probably benign |
Het |
| Cblif |
A |
G |
19: 11,735,102 (GRCm39) |
T241A |
probably benign |
Het |
| Celsr1 |
A |
T |
15: 85,815,549 (GRCm39) |
V1822E |
possibly damaging |
Het |
| Chgb |
C |
G |
2: 132,635,154 (GRCm39) |
S365R |
probably damaging |
Het |
| Cnih3 |
T |
C |
1: 181,180,857 (GRCm39) |
|
probably benign |
Het |
| Dcaf1 |
T |
A |
9: 106,735,528 (GRCm39) |
D825E |
possibly damaging |
Het |
| Dlx3 |
T |
C |
11: 95,011,430 (GRCm39) |
Y95H |
probably benign |
Het |
| Dmbt1 |
A |
T |
7: 130,668,208 (GRCm39) |
E488V |
unknown |
Het |
| Espnl |
A |
G |
1: 91,273,595 (GRCm39) |
Y985C |
probably damaging |
Het |
| Frmpd2 |
T |
C |
14: 33,272,010 (GRCm39) |
V1048A |
probably damaging |
Het |
| Fxn |
A |
T |
19: 24,249,787 (GRCm39) |
L100Q |
probably damaging |
Het |
| Gapvd1 |
T |
A |
2: 34,607,318 (GRCm39) |
D560V |
probably damaging |
Het |
| Gm4924 |
T |
A |
10: 82,213,490 (GRCm39) |
H429Q |
unknown |
Het |
| Gpr158 |
T |
C |
2: 21,787,972 (GRCm39) |
F538L |
probably benign |
Het |
| Itpr1 |
T |
A |
6: 108,378,308 (GRCm39) |
M1278K |
possibly damaging |
Het |
| Ivd |
T |
A |
2: 118,708,369 (GRCm39) |
V361E |
probably damaging |
Het |
| Kcnh6 |
T |
C |
11: 105,899,821 (GRCm39) |
L30P |
probably damaging |
Het |
| Lipo4 |
C |
T |
19: 33,495,074 (GRCm39) |
V35I |
probably benign |
Het |
| Lmo7 |
A |
G |
14: 102,155,076 (GRCm39) |
D1200G |
probably damaging |
Het |
| Med1 |
T |
A |
11: 98,080,049 (GRCm39) |
R31* |
probably null |
Het |
| Mill2 |
A |
T |
7: 18,573,950 (GRCm39) |
R12* |
probably null |
Het |
| Mphosph8 |
A |
G |
14: 56,934,114 (GRCm39) |
|
probably null |
Het |
| Mtfr2 |
T |
A |
10: 20,233,039 (GRCm39) |
S203T |
possibly damaging |
Het |
| Muc5ac |
A |
C |
7: 141,362,559 (GRCm39) |
T1957P |
unknown |
Het |
| Mxi1 |
C |
A |
19: 53,299,213 (GRCm39) |
P28Q |
probably benign |
Het |
| Mycbpap |
T |
C |
11: 94,393,995 (GRCm39) |
D367G |
probably damaging |
Het |
| Nav3 |
T |
C |
10: 109,605,176 (GRCm39) |
T966A |
probably benign |
Het |
| Nbea |
AC |
A |
3: 55,998,393 (GRCm39) |
|
probably null |
Het |
| Ndst2 |
A |
T |
14: 20,775,470 (GRCm39) |
F673L |
possibly damaging |
Het |
| Ndst3 |
T |
A |
3: 123,340,518 (GRCm39) |
I767F |
probably benign |
Het |
| Nell1 |
A |
T |
7: 50,503,683 (GRCm39) |
D696V |
probably damaging |
Het |
| Nol9 |
A |
T |
4: 152,124,109 (GRCm39) |
T100S |
probably benign |
Het |
| Nr4a1 |
T |
C |
15: 101,168,245 (GRCm39) |
S94P |
probably damaging |
Het |
| Nrdc |
T |
C |
4: 108,858,121 (GRCm39) |
I31T |
probably damaging |
Het |
| Oas2 |
T |
A |
5: 120,887,576 (GRCm39) |
D88V |
probably damaging |
Het |
| Or8w1 |
T |
C |
2: 87,465,774 (GRCm39) |
I106V |
probably benign |
Het |
| Pex6 |
A |
G |
17: 47,022,991 (GRCm39) |
H189R |
probably benign |
Het |
| Pgap1 |
A |
G |
1: 54,575,206 (GRCm39) |
S239P |
probably damaging |
Het |
| Pheta1 |
C |
T |
5: 121,991,147 (GRCm39) |
P170S |
possibly damaging |
Het |
| Plec |
A |
G |
15: 76,067,721 (GRCm39) |
|
probably null |
Het |
| Plekhg5 |
T |
C |
4: 152,192,780 (GRCm39) |
V582A |
probably benign |
Het |
| Plekhh2 |
G |
T |
17: 84,873,841 (GRCm39) |
E375D |
probably benign |
Het |
| Pramel55 |
G |
T |
5: 95,949,545 (GRCm39) |
R97S |
probably damaging |
Het |
| Prp2rt |
A |
G |
13: 97,235,724 (GRCm39) |
S8P |
probably benign |
Het |
| Psmd4 |
G |
A |
3: 94,940,767 (GRCm39) |
T332I |
probably benign |
Het |
| Ptprc |
T |
A |
1: 138,041,485 (GRCm39) |
T76S |
probably benign |
Het |
| Rab44 |
A |
T |
17: 29,358,315 (GRCm39) |
I168L |
|
Het |
| Ros1 |
T |
C |
10: 51,958,061 (GRCm39) |
T1872A |
probably benign |
Het |
| Scgb1b24 |
A |
T |
7: 33,443,493 (GRCm39) |
K51* |
probably null |
Het |
| Scube2 |
A |
T |
7: 109,428,345 (GRCm39) |
D509E |
probably benign |
Het |
| Sgo2b |
A |
T |
8: 64,393,067 (GRCm39) |
S123R |
probably damaging |
Het |
| Smc3 |
G |
C |
19: 53,617,150 (GRCm39) |
R521P |
possibly damaging |
Het |
| Socs4 |
G |
A |
14: 47,528,034 (GRCm39) |
R323H |
probably damaging |
Het |
| Socs5 |
T |
A |
17: 87,441,067 (GRCm39) |
D2E |
probably benign |
Het |
| Sra1 |
A |
G |
18: 36,810,299 (GRCm39) |
V121A |
probably damaging |
Het |
| Stimate |
T |
C |
14: 30,594,645 (GRCm39) |
S253P |
probably benign |
Het |
| Tanc1 |
T |
C |
2: 59,601,548 (GRCm39) |
L143P |
probably damaging |
Het |
| Tcerg1l |
A |
T |
7: 137,811,490 (GRCm39) |
F568Y |
probably damaging |
Het |
| Trpm7 |
T |
C |
2: 126,671,140 (GRCm39) |
E614G |
probably damaging |
Het |
| Tuba4a |
G |
T |
1: 75,192,686 (GRCm39) |
H337Q |
|
Het |
| Tubgcp6 |
G |
A |
15: 88,985,100 (GRCm39) |
H1663Y |
probably damaging |
Het |
| Ush2a |
A |
G |
1: 188,175,316 (GRCm39) |
Y1138C |
probably damaging |
Het |
| Vmn1r18 |
A |
T |
6: 57,367,535 (GRCm39) |
N6K |
possibly damaging |
Het |
| Vmn1r213 |
G |
A |
13: 23,195,944 (GRCm39) |
A176T |
|
Het |
| Vmn1r215 |
A |
T |
13: 23,260,749 (GRCm39) |
H263L |
probably benign |
Het |
| Vmn2r51 |
CGGCCAATAGAAGAAACTTTTACCTTCAAGCAGTGAGAACTGGC |
CGGC |
7: 9,833,712 (GRCm39) |
|
probably benign |
Het |
| Wdhd1 |
A |
C |
14: 47,489,427 (GRCm39) |
L702* |
probably null |
Het |
| Zc3h12a |
T |
C |
4: 125,020,558 (GRCm39) |
E95G |
probably benign |
Het |
|
| Other mutations in Carmil1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00096:Carmil1
|
APN |
13 |
24,295,821 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL00392:Carmil1
|
APN |
13 |
24,278,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00943:Carmil1
|
APN |
13 |
24,295,869 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL01375:Carmil1
|
APN |
13 |
24,278,454 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02043:Carmil1
|
APN |
13 |
24,208,299 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02122:Carmil1
|
APN |
13 |
24,220,541 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02178:Carmil1
|
APN |
13 |
24,278,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02264:Carmil1
|
APN |
13 |
24,259,699 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02269:Carmil1
|
APN |
13 |
24,339,393 (GRCm39) |
nonsense |
probably null |
|
|
IGL02546:Carmil1
|
APN |
13 |
24,299,482 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02740:Carmil1
|
APN |
13 |
24,278,501 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02876:Carmil1
|
APN |
13 |
24,338,651 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02976:Carmil1
|
APN |
13 |
24,276,534 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL03012:Carmil1
|
APN |
13 |
24,220,355 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL03107:Carmil1
|
APN |
13 |
24,278,438 (GRCm39) |
missense |
probably damaging |
0.99 |
|
H8562:Carmil1
|
UTSW |
13 |
24,248,630 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0085:Carmil1
|
UTSW |
13 |
24,209,850 (GRCm39) |
missense |
probably benign |
|
|
R0119:Carmil1
|
UTSW |
13 |
24,266,003 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0166:Carmil1
|
UTSW |
13 |
24,283,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0299:Carmil1
|
UTSW |
13 |
24,266,003 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0304:Carmil1
|
UTSW |
13 |
24,323,324 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0335:Carmil1
|
UTSW |
13 |
24,257,966 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0369:Carmil1
|
UTSW |
13 |
24,266,003 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0462:Carmil1
|
UTSW |
13 |
24,206,494 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1203:Carmil1
|
UTSW |
13 |
24,282,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1540:Carmil1
|
UTSW |
13 |
24,283,037 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1730:Carmil1
|
UTSW |
13 |
24,225,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1770:Carmil1
|
UTSW |
13 |
24,357,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1831:Carmil1
|
UTSW |
13 |
24,348,862 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1893:Carmil1
|
UTSW |
13 |
24,208,446 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2099:Carmil1
|
UTSW |
13 |
24,357,650 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2153:Carmil1
|
UTSW |
13 |
24,325,656 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2296:Carmil1
|
UTSW |
13 |
24,299,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2869:Carmil1
|
UTSW |
13 |
24,229,051 (GRCm39) |
synonymous |
silent |
|
|
R2872:Carmil1
|
UTSW |
13 |
24,229,051 (GRCm39) |
synonymous |
silent |
|
|
R3113:Carmil1
|
UTSW |
13 |
24,253,740 (GRCm39) |
missense |
probably benign |
0.22 |
|
R3508:Carmil1
|
UTSW |
13 |
24,203,659 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R3780:Carmil1
|
UTSW |
13 |
24,321,152 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3954:Carmil1
|
UTSW |
13 |
24,197,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4027:Carmil1
|
UTSW |
13 |
24,251,206 (GRCm39) |
splice site |
probably benign |
|
|
R4086:Carmil1
|
UTSW |
13 |
24,208,444 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4647:Carmil1
|
UTSW |
13 |
24,321,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Carmil1
|
UTSW |
13 |
24,325,659 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R4792:Carmil1
|
UTSW |
13 |
24,251,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5012:Carmil1
|
UTSW |
13 |
24,208,403 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5166:Carmil1
|
UTSW |
13 |
24,338,966 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5199:Carmil1
|
UTSW |
13 |
24,295,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5330:Carmil1
|
UTSW |
13 |
24,209,929 (GRCm39) |
splice site |
probably null |
|
|
R5472:Carmil1
|
UTSW |
13 |
24,339,454 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5478:Carmil1
|
UTSW |
13 |
24,296,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5496:Carmil1
|
UTSW |
13 |
24,339,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5775:Carmil1
|
UTSW |
13 |
24,460,520 (GRCm39) |
missense |
probably benign |
|
|
R5789:Carmil1
|
UTSW |
13 |
24,305,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5794:Carmil1
|
UTSW |
13 |
24,276,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5977:Carmil1
|
UTSW |
13 |
24,253,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6127:Carmil1
|
UTSW |
13 |
24,220,335 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6128:Carmil1
|
UTSW |
13 |
24,197,177 (GRCm39) |
nonsense |
probably null |
|
|
R6403:Carmil1
|
UTSW |
13 |
24,265,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6450:Carmil1
|
UTSW |
13 |
24,220,547 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6451:Carmil1
|
UTSW |
13 |
24,276,541 (GRCm39) |
nonsense |
probably null |
|
|
R6684:Carmil1
|
UTSW |
13 |
24,206,525 (GRCm39) |
missense |
unknown |
|
|
R6891:Carmil1
|
UTSW |
13 |
24,325,706 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6902:Carmil1
|
UTSW |
13 |
24,299,528 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6924:Carmil1
|
UTSW |
13 |
24,259,667 (GRCm39) |
nonsense |
probably null |
|
|
R6946:Carmil1
|
UTSW |
13 |
24,299,528 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R7038:Carmil1
|
UTSW |
13 |
24,323,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Carmil1
|
UTSW |
13 |
24,204,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7282:Carmil1
|
UTSW |
13 |
24,197,387 (GRCm39) |
missense |
probably benign |
|
|
R7286:Carmil1
|
UTSW |
13 |
24,197,377 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7397:Carmil1
|
UTSW |
13 |
24,228,294 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7412:Carmil1
|
UTSW |
13 |
24,282,793 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7611:Carmil1
|
UTSW |
13 |
24,197,315 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7642:Carmil1
|
UTSW |
13 |
24,251,189 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7827:Carmil1
|
UTSW |
13 |
24,220,421 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7890:Carmil1
|
UTSW |
13 |
24,197,215 (GRCm39) |
missense |
|
|
|
R8014:Carmil1
|
UTSW |
13 |
24,220,304 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8068:Carmil1
|
UTSW |
13 |
24,259,711 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8214:Carmil1
|
UTSW |
13 |
24,228,215 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8247:Carmil1
|
UTSW |
13 |
24,282,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8272:Carmil1
|
UTSW |
13 |
24,220,562 (GRCm39) |
missense |
probably benign |
|
|
R8318:Carmil1
|
UTSW |
13 |
24,220,442 (GRCm39) |
missense |
probably benign |
|
|
R8361:Carmil1
|
UTSW |
13 |
24,251,113 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8469:Carmil1
|
UTSW |
13 |
24,296,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8558:Carmil1
|
UTSW |
13 |
24,209,863 (GRCm39) |
missense |
probably benign |
|
|
R8698:Carmil1
|
UTSW |
13 |
24,220,229 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8722:Carmil1
|
UTSW |
13 |
24,220,568 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8836:Carmil1
|
UTSW |
13 |
24,339,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8915:Carmil1
|
UTSW |
13 |
24,325,709 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8931:Carmil1
|
UTSW |
13 |
24,338,704 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8932:Carmil1
|
UTSW |
13 |
24,197,179 (GRCm39) |
missense |
|
|
|
R9004:Carmil1
|
UTSW |
13 |
24,225,662 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9041:Carmil1
|
UTSW |
13 |
24,282,793 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R9103:Carmil1
|
UTSW |
13 |
24,295,836 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9224:Carmil1
|
UTSW |
13 |
24,292,512 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9460:Carmil1
|
UTSW |
13 |
24,253,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9502:Carmil1
|
UTSW |
13 |
24,323,357 (GRCm39) |
missense |
probably benign |
|
|
R9548:Carmil1
|
UTSW |
13 |
24,460,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0025:Carmil1
|
UTSW |
13 |
24,283,026 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
Z1088:Carmil1
|
UTSW |
13 |
24,228,165 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGCCCTCAAACTTACAGCTATG -3'
(R):5'- CTCTGGAGATGGTAATGCCTC -3'
Sequencing Primer
(F):5'- TTTCCAAGTCAGCTACAGAGGTC -3'
(R):5'- GGAGATGGTAATGCCTCTTTCTACTC -3'
|
| Posted On |
2022-05-16 |
Incidental Mutation