Incidental Mutation 'R9454:Ralgapb'
| ID |
714448 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ralgapb
|
| Ensembl Gene |
ENSMUSG00000027652 |
| Gene Name |
Ral GTPase activating protein, beta subunit (non-catalytic) |
| Synonyms |
B230339M05Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9454 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
158251768-158341173 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 158315072 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 1146
(H1146Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000105111
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046274]
[ENSMUST00000109485]
[ENSMUST00000109486]
[ENSMUST00000141497]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000046274
AA Change: H1130Q
PolyPhen 2
Score 0.490 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000048430
Gene: ENSMUSG00000027652
AA Change: H1130Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
775 |
788 |
N/A |
INTRINSIC |
|
low complexity region
|
910 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1097 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1321 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000109485
AA Change: H1146Q
PolyPhen 2
Score 0.300 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000105111
Gene: ENSMUSG00000027652
AA Change: H1146Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
637 |
N/A |
INTRINSIC |
|
low complexity region
|
791 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
926 |
936 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1325 |
1337 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000109486
AA Change: H1134Q
PolyPhen 2
Score 0.490 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000105112
Gene: ENSMUSG00000027652
AA Change: H1134Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
914 |
924 |
N/A |
INTRINSIC |
|
low complexity region
|
1090 |
1101 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1325 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000141497
AA Change: H812Q
PolyPhen 2
Score 0.490 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000116481
Gene: ENSMUSG00000027652
AA Change: H812Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
288 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
470 |
N/A |
INTRINSIC |
|
low complexity region
|
592 |
602 |
N/A |
INTRINSIC |
|
low complexity region
|
768 |
779 |
N/A |
INTRINSIC |
|
low complexity region
|
991 |
1003 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ablim3 |
G |
T |
18: 61,952,067 (GRCm39) |
H431Q |
possibly damaging |
Het |
| Adam25 |
A |
T |
8: 41,207,486 (GRCm39) |
I251F |
probably damaging |
Het |
| Ankrd31 |
A |
T |
13: 96,916,842 (GRCm39) |
T119S |
probably damaging |
Het |
| Ankrd31 |
T |
C |
13: 96,916,846 (GRCm39) |
V120A |
possibly damaging |
Het |
| Anks6 |
T |
C |
4: 47,016,789 (GRCm39) |
E809G |
possibly damaging |
Het |
| Arhgap21 |
A |
T |
2: 20,870,153 (GRCm39) |
S928T |
probably damaging |
Het |
| Arhgef10l |
G |
T |
4: 140,308,236 (GRCm39) |
S39* |
probably null |
Het |
| Aspm |
G |
A |
1: 139,408,732 (GRCm39) |
E2540K |
probably benign |
Het |
| Atp10a |
T |
C |
7: 58,308,339 (GRCm39) |
I46T |
probably benign |
Het |
| Atp13a5 |
C |
A |
16: 29,133,338 (GRCm39) |
V483L |
possibly damaging |
Het |
| BC028528 |
T |
C |
3: 95,797,082 (GRCm39) |
D29G |
possibly damaging |
Het |
| Ccdc187 |
T |
A |
2: 26,166,114 (GRCm39) |
T772S |
possibly damaging |
Het |
| Ccnh |
G |
A |
13: 85,350,521 (GRCm39) |
A199T |
probably benign |
Het |
| Cfap65 |
A |
T |
1: 74,944,210 (GRCm39) |
Y1504N |
probably damaging |
Het |
| Ckap2 |
C |
A |
8: 22,665,899 (GRCm39) |
E383* |
probably null |
Het |
| Clec4n |
T |
C |
6: 123,212,532 (GRCm39) |
V116A |
possibly damaging |
Het |
| Cmc2 |
G |
T |
8: 117,616,550 (GRCm39) |
D58E |
unknown |
Het |
| Cntn6 |
A |
G |
6: 104,781,308 (GRCm39) |
K465E |
possibly damaging |
Het |
| Col6a6 |
G |
A |
9: 105,661,059 (GRCm39) |
A350V |
probably damaging |
Het |
| Cps1 |
A |
G |
1: 67,219,311 (GRCm39) |
I884V |
probably damaging |
Het |
| E2f7 |
C |
T |
10: 110,620,542 (GRCm39) |
A853V |
probably benign |
Het |
| E330034G19Rik |
A |
T |
14: 24,346,860 (GRCm39) |
Q114L |
unknown |
Het |
| Egfr |
G |
T |
11: 16,837,155 (GRCm39) |
G632V |
probably damaging |
Het |
| Fam98b |
T |
C |
2: 117,080,250 (GRCm39) |
M1T |
probably null |
Het |
| Fcgr2b |
T |
A |
1: 170,788,657 (GRCm39) |
I317F |
probably damaging |
Het |
| Galntl6 |
T |
C |
8: 58,411,435 (GRCm39) |
D265G |
probably damaging |
Het |
| Gm4922 |
A |
G |
10: 18,660,329 (GRCm39) |
L131P |
probably damaging |
Het |
| H1f7 |
T |
C |
15: 98,154,823 (GRCm39) |
I109V |
probably benign |
Het |
| H2-Q1 |
A |
T |
17: 35,540,349 (GRCm39) |
I145F |
probably damaging |
Het |
| Heatr5a |
AGCACACTGCAGGAAGCTCACACAGCACAGCATACCTTCAGGAGTGCACACTGCAGGAAGCTCACACAGCACAGCATACCTTCAGGAGAGCACACTGCAGGAAGCTCA |
AGCACACTGCAGGAAGCTCACACAGCACAGCATACCTTCAGGAGAGCACACTGCAGGAAGCTCA |
12: 51,934,702 (GRCm39) |
|
probably benign |
Het |
| Ica1 |
A |
T |
6: 8,667,288 (GRCm39) |
S293T |
probably benign |
Het |
| Ift70a2 |
T |
A |
2: 75,806,812 (GRCm39) |
I567F |
probably benign |
Het |
| Klra5 |
C |
A |
6: 129,883,686 (GRCm39) |
W147L |
possibly damaging |
Het |
| Magi2 |
G |
T |
5: 20,671,176 (GRCm39) |
V507F |
probably damaging |
Het |
| Malrd1 |
G |
A |
2: 15,802,537 (GRCm39) |
W1083* |
probably null |
Het |
| Malrd1 |
T |
C |
2: 15,757,660 (GRCm39) |
I978T |
unknown |
Het |
| Mgarp |
T |
C |
3: 51,303,902 (GRCm39) |
T10A |
probably damaging |
Het |
| Mtnr1a |
A |
G |
8: 45,538,612 (GRCm39) |
I17V |
|
Het |
| Muc5ac |
C |
T |
7: 141,362,431 (GRCm39) |
T1914I |
unknown |
Het |
| Naf1 |
GCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAACTGGGATGCGGGCGGAAGACCACCACCGCCGCCAGCCCCGAACTCGGATCCCGGCGGAAGACC |
GCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAACTGGGATGCGGGCGGAAGACCACCACCGCCGCCAGCCCCGAACTCGGATCCCGGCGGAAGACC |
8: 67,313,200 (GRCm39) |
|
probably benign |
Het |
| Nav3 |
T |
C |
10: 109,835,864 (GRCm39) |
T73A |
probably benign |
Het |
| Or4b1 |
A |
C |
2: 89,979,820 (GRCm39) |
C177G |
probably damaging |
Het |
| Or8k21 |
A |
T |
2: 86,145,178 (GRCm39) |
Y151N |
probably damaging |
Het |
| Pclo |
T |
A |
5: 14,762,452 (GRCm39) |
S357T |
probably benign |
Het |
| Pkdrej |
T |
A |
15: 85,702,420 (GRCm39) |
N1172I |
probably benign |
Het |
| Psmb9 |
G |
A |
17: 34,402,078 (GRCm39) |
R173C |
probably benign |
Het |
| Raph1 |
T |
A |
1: 60,528,753 (GRCm39) |
Q836L |
unknown |
Het |
| Rcc1 |
A |
G |
4: 132,062,074 (GRCm39) |
S280P |
probably damaging |
Het |
| Recql |
T |
C |
6: 142,320,617 (GRCm39) |
M144V |
possibly damaging |
Het |
| Rela |
T |
C |
19: 5,695,368 (GRCm39) |
I298T |
probably damaging |
Het |
| Rfc1 |
T |
A |
5: 65,431,774 (GRCm39) |
I792F |
|
Het |
| Rnf31 |
A |
G |
14: 55,833,609 (GRCm39) |
E539G |
|
Het |
| Rrp9 |
T |
C |
9: 106,360,840 (GRCm39) |
S274P |
possibly damaging |
Het |
| Rsf1 |
CGGCGGCGG |
CGGCGGCGGGGGCGGCGG |
7: 97,229,130 (GRCm39) |
|
probably benign |
Het |
| Scmh1 |
A |
G |
4: 120,372,276 (GRCm39) |
I360V |
probably benign |
Het |
| Sh3yl1 |
T |
C |
12: 30,990,420 (GRCm39) |
|
probably null |
Het |
| Shisa9 |
T |
C |
16: 11,802,523 (GRCm39) |
S27P |
probably benign |
Het |
| Slc17a4 |
A |
G |
13: 24,085,910 (GRCm39) |
V359A |
probably benign |
Het |
| Slfn5 |
C |
A |
11: 82,850,885 (GRCm39) |
A394E |
probably benign |
Het |
| Sun3 |
A |
G |
11: 8,988,281 (GRCm39) |
F14L |
probably benign |
Het |
| Surf1 |
A |
T |
2: 26,804,808 (GRCm39) |
D148E |
possibly damaging |
Het |
| Syne2 |
A |
T |
12: 76,141,844 (GRCm39) |
K1388* |
probably null |
Het |
| Syne2 |
A |
G |
12: 76,067,275 (GRCm39) |
K4325E |
probably damaging |
Het |
| Tacr1 |
A |
G |
6: 82,531,853 (GRCm39) |
M250V |
probably damaging |
Het |
| Tenm2 |
T |
C |
11: 36,112,286 (GRCm39) |
T420A |
probably benign |
Het |
| Tm7sf3 |
C |
A |
6: 146,520,041 (GRCm39) |
A282S |
probably benign |
Het |
| Tmf1 |
T |
C |
6: 97,155,866 (GRCm39) |
E40G |
probably benign |
Het |
| Tnfrsf12a |
A |
G |
17: 23,895,491 (GRCm39) |
|
probably null |
Het |
| Unc80 |
C |
A |
1: 66,734,749 (GRCm39) |
H3325Q |
possibly damaging |
Het |
| Vamp9 |
C |
T |
5: 100,070,952 (GRCm39) |
P76S |
probably damaging |
Het |
| Zfp142 |
A |
G |
1: 74,609,016 (GRCm39) |
L1593S |
probably damaging |
Het |
| Zfp869 |
T |
A |
8: 70,159,241 (GRCm39) |
Y444F |
probably benign |
Het |
| Zscan10 |
G |
A |
17: 23,826,619 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Ralgapb |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00094:Ralgapb
|
APN |
2 |
158,262,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00534:Ralgapb
|
APN |
2 |
158,272,420 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01362:Ralgapb
|
APN |
2 |
158,277,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01653:Ralgapb
|
APN |
2 |
158,304,079 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01704:Ralgapb
|
APN |
2 |
158,262,795 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02000:Ralgapb
|
APN |
2 |
158,296,034 (GRCm39) |
splice site |
probably benign |
|
|
IGL02169:Ralgapb
|
APN |
2 |
158,268,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02516:Ralgapb
|
APN |
2 |
158,307,735 (GRCm39) |
splice site |
probably benign |
|
|
IGL02548:Ralgapb
|
APN |
2 |
158,286,585 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02550:Ralgapb
|
APN |
2 |
158,290,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02653:Ralgapb
|
APN |
2 |
158,285,229 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02744:Ralgapb
|
APN |
2 |
158,288,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02804:Ralgapb
|
APN |
2 |
158,268,204 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL02937:Ralgapb
|
APN |
2 |
158,334,936 (GRCm39) |
splice site |
probably null |
|
|
IGL02993:Ralgapb
|
APN |
2 |
158,279,314 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL03154:Ralgapb
|
APN |
2 |
158,274,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Ralgapb
|
APN |
2 |
158,307,832 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL03347:Ralgapb
|
APN |
2 |
158,307,880 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
Chacha
|
UTSW |
2 |
158,334,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Gato
|
UTSW |
2 |
158,286,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Kibble
|
UTSW |
2 |
158,279,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ralston
|
UTSW |
2 |
158,296,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4142001:Ralgapb
|
UTSW |
2 |
158,272,342 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0037:Ralgapb
|
UTSW |
2 |
158,279,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0037:Ralgapb
|
UTSW |
2 |
158,279,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0077:Ralgapb
|
UTSW |
2 |
158,315,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0581:Ralgapb
|
UTSW |
2 |
158,334,881 (GRCm39) |
missense |
probably benign |
|
|
R0629:Ralgapb
|
UTSW |
2 |
158,281,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0839:Ralgapb
|
UTSW |
2 |
158,315,203 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1331:Ralgapb
|
UTSW |
2 |
158,272,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Ralgapb
|
UTSW |
2 |
158,304,173 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1468:Ralgapb
|
UTSW |
2 |
158,304,173 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1540:Ralgapb
|
UTSW |
2 |
158,307,746 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1572:Ralgapb
|
UTSW |
2 |
158,288,119 (GRCm39) |
splice site |
probably benign |
|
|
R1628:Ralgapb
|
UTSW |
2 |
158,272,383 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1718:Ralgapb
|
UTSW |
2 |
158,285,200 (GRCm39) |
nonsense |
probably null |
|
|
R1777:Ralgapb
|
UTSW |
2 |
158,304,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1822:Ralgapb
|
UTSW |
2 |
158,334,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1903:Ralgapb
|
UTSW |
2 |
158,337,483 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1909:Ralgapb
|
UTSW |
2 |
158,286,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2157:Ralgapb
|
UTSW |
2 |
158,279,392 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4524:Ralgapb
|
UTSW |
2 |
158,279,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4946:Ralgapb
|
UTSW |
2 |
158,282,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4975:Ralgapb
|
UTSW |
2 |
158,277,428 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5014:Ralgapb
|
UTSW |
2 |
158,337,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5165:Ralgapb
|
UTSW |
2 |
158,307,832 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5465:Ralgapb
|
UTSW |
2 |
158,290,325 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5526:Ralgapb
|
UTSW |
2 |
158,274,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5566:Ralgapb
|
UTSW |
2 |
158,336,630 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5949:Ralgapb
|
UTSW |
2 |
158,296,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6140:Ralgapb
|
UTSW |
2 |
158,298,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Ralgapb
|
UTSW |
2 |
158,288,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6192:Ralgapb
|
UTSW |
2 |
158,291,367 (GRCm39) |
splice site |
probably null |
|
|
R6364:Ralgapb
|
UTSW |
2 |
158,304,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6458:Ralgapb
|
UTSW |
2 |
158,286,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6746:Ralgapb
|
UTSW |
2 |
158,318,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6782:Ralgapb
|
UTSW |
2 |
158,278,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6788:Ralgapb
|
UTSW |
2 |
158,278,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7017:Ralgapb
|
UTSW |
2 |
158,290,257 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7108:Ralgapb
|
UTSW |
2 |
158,336,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7108:Ralgapb
|
UTSW |
2 |
158,334,380 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7236:Ralgapb
|
UTSW |
2 |
158,282,747 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7454:Ralgapb
|
UTSW |
2 |
158,274,822 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7485:Ralgapb
|
UTSW |
2 |
158,285,275 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7595:Ralgapb
|
UTSW |
2 |
158,268,085 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7615:Ralgapb
|
UTSW |
2 |
158,292,190 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7728:Ralgapb
|
UTSW |
2 |
158,324,423 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7913:Ralgapb
|
UTSW |
2 |
158,307,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7953:Ralgapb
|
UTSW |
2 |
158,307,803 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8245:Ralgapb
|
UTSW |
2 |
158,285,256 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8337:Ralgapb
|
UTSW |
2 |
158,292,192 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8363:Ralgapb
|
UTSW |
2 |
158,268,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Ralgapb
|
UTSW |
2 |
158,268,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8673:Ralgapb
|
UTSW |
2 |
158,292,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8955:Ralgapb
|
UTSW |
2 |
158,337,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8955:Ralgapb
|
UTSW |
2 |
158,279,264 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8992:Ralgapb
|
UTSW |
2 |
158,296,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9013:Ralgapb
|
UTSW |
2 |
158,279,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9141:Ralgapb
|
UTSW |
2 |
158,262,811 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9166:Ralgapb
|
UTSW |
2 |
158,274,842 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9242:Ralgapb
|
UTSW |
2 |
158,277,386 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9274:Ralgapb
|
UTSW |
2 |
158,278,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9354:Ralgapb
|
UTSW |
2 |
158,279,313 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9489:Ralgapb
|
UTSW |
2 |
158,268,283 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9490:Ralgapb
|
UTSW |
2 |
158,334,350 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9510:Ralgapb
|
UTSW |
2 |
158,285,856 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Ralgapb
|
UTSW |
2 |
158,277,475 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AACCTCAATTGTCTAAAGCAAGTAAA -3'
(R):5'- TTGTATGTTTATAGCACAGAAAGACG -3'
Sequencing Primer
(F):5'- CTTGATGTATGAACACACTCAAGGAC -3'
(R):5'- GACGGAAAGTTCAGAATCCTTAC -3'
|
| Posted On |
2022-06-15 |
Incidental Mutation