Incidental Mutation 'R9462:N4bp2'
| ID |
714923 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
N4bp2
|
| Ensembl Gene |
ENSMUSG00000037795 |
| Gene Name |
NEDD4 binding protein 2 |
| Synonyms |
LOC333789, B3bp, LOC386488 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.190)
|
| Stock # |
R9462 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
65920864-65987451 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 65947898 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Aspartic acid
at position 176
(G176D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144278
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000087264]
[ENSMUST00000201489]
[ENSMUST00000201615]
|
| AlphaFold |
F8VQG7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000087264
AA Change: G176D
PolyPhen 2
Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000084519
Gene: ENSMUSG00000037795
AA Change: G176D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1.1e-15 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201489
AA Change: G176D
PolyPhen 2
Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000143807
Gene: ENSMUSG00000037795
AA Change: G176D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1e-14 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201615
AA Change: G176D
PolyPhen 2
Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000144278
Gene: ENSMUSG00000037795
AA Change: G176D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1.2e-14 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
8e-10 |
BLAST |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
|
| Allele List at MGI |
All alleles(9) : Targeted, other(2) Gene trapped(7)
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4921539E11Rik |
G |
A |
4: 103,092,964 (GRCm39) |
T220I |
probably benign |
Het |
| Abca8b |
T |
A |
11: 109,844,433 (GRCm39) |
H928L |
|
Het |
| Ahnak |
A |
T |
19: 8,981,299 (GRCm39) |
D861V |
probably damaging |
Het |
| Ahnak2 |
C |
A |
12: 112,750,655 (GRCm39) |
R89L |
|
Het |
| Aipl1 |
C |
T |
11: 71,928,253 (GRCm39) |
G11D |
probably damaging |
Het |
| Anks6 |
A |
G |
4: 47,033,142 (GRCm39) |
L573P |
unknown |
Het |
| Ano5 |
T |
C |
7: 51,235,200 (GRCm39) |
V711A |
probably benign |
Het |
| Arl2bp |
C |
A |
8: 95,398,755 (GRCm39) |
A120D |
probably damaging |
Het |
| Asap1 |
A |
G |
15: 64,038,328 (GRCm39) |
Y223H |
probably damaging |
Het |
| Atp7b |
A |
T |
8: 22,490,160 (GRCm39) |
M1151K |
probably damaging |
Het |
| B4galnt3 |
A |
T |
6: 120,271,438 (GRCm39) |
L28Q |
probably null |
Het |
| Ccdc39 |
T |
C |
3: 33,868,519 (GRCm39) |
K856E |
probably benign |
Het |
| Ccr9 |
A |
G |
9: 123,608,600 (GRCm39) |
D94G |
probably damaging |
Het |
| Cdan1 |
A |
G |
2: 120,560,060 (GRCm39) |
I368T |
possibly damaging |
Het |
| Cdhr17 |
G |
T |
5: 17,027,213 (GRCm39) |
A379S |
|
Het |
| Cfap54 |
T |
C |
10: 92,737,920 (GRCm39) |
Q2326R |
unknown |
Het |
| Chrm3 |
T |
C |
13: 9,927,437 (GRCm39) |
Y533C |
|
Het |
| Ckap4 |
C |
T |
10: 84,363,924 (GRCm39) |
E380K |
possibly damaging |
Het |
| Cntnap2 |
T |
C |
6: 46,211,217 (GRCm39) |
F544L |
probably damaging |
Het |
| Cwh43 |
A |
G |
5: 73,591,695 (GRCm39) |
K596R |
probably benign |
Het |
| Cyp26c1 |
A |
G |
19: 37,681,634 (GRCm39) |
E479G |
probably damaging |
Het |
| Deup1 |
A |
G |
9: 15,493,882 (GRCm39) |
V420A |
probably benign |
Het |
| Dnah3 |
A |
G |
7: 119,551,523 (GRCm39) |
V2932A |
probably benign |
Het |
| Dthd1 |
G |
A |
5: 63,039,626 (GRCm39) |
R676H |
probably benign |
Het |
| Eef1e1 |
A |
G |
13: 38,838,997 (GRCm39) |
L120P |
probably damaging |
Het |
| Elane |
T |
C |
10: 79,723,883 (GRCm39) |
S244P |
probably benign |
Het |
| Esp6 |
A |
G |
17: 40,876,315 (GRCm39) |
E121G |
probably benign |
Het |
| Eya1 |
T |
C |
1: 14,299,775 (GRCm39) |
E326G |
probably damaging |
Het |
| Fut2 |
G |
T |
7: 45,300,492 (GRCm39) |
N93K |
probably damaging |
Het |
| Garin5b |
A |
G |
7: 4,761,330 (GRCm39) |
S461P |
|
Het |
| Gm12695 |
A |
G |
4: 96,651,075 (GRCm39) |
V126A |
probably benign |
Het |
| Gucy2g |
A |
G |
19: 55,221,469 (GRCm39) |
|
probably null |
Het |
| Hbs1l |
T |
C |
10: 21,218,304 (GRCm39) |
V267A |
probably damaging |
Het |
| Hsd17b1 |
A |
T |
11: 100,969,806 (GRCm39) |
N106I |
possibly damaging |
Het |
| Ino80d |
G |
A |
1: 63,097,393 (GRCm39) |
L939F |
probably damaging |
Het |
| Lilra6 |
A |
G |
7: 3,914,994 (GRCm39) |
W505R |
probably damaging |
Het |
| Map3k14 |
T |
A |
11: 103,118,360 (GRCm39) |
K609* |
probably null |
Het |
| Mark1 |
T |
A |
1: 184,651,868 (GRCm39) |
K212N |
probably damaging |
Het |
| Muc5b |
T |
A |
7: 141,415,216 (GRCm39) |
C2721S |
|
Het |
| Myh4 |
A |
G |
11: 67,141,811 (GRCm39) |
D890G |
possibly damaging |
Het |
| Mylk2 |
T |
G |
2: 152,761,373 (GRCm39) |
L492R |
probably damaging |
Het |
| Myt1 |
T |
A |
2: 181,467,729 (GRCm39) |
Y1134* |
probably null |
Het |
| Ncstn |
A |
C |
1: 171,899,707 (GRCm39) |
M325R |
probably damaging |
Het |
| Ndor1 |
C |
T |
2: 25,144,875 (GRCm39) |
|
probably null |
Het |
| Notch4 |
G |
A |
17: 34,806,667 (GRCm39) |
R1868H |
probably benign |
Het |
| Ogfr |
AGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCAAAAGGCCAGGTGGAGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAAGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGGGGCCAGAG |
AGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCAAAAGGCCAGGTGGAGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAAGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGGGGCCAGAG |
2: 180,236,850 (GRCm39) |
|
probably benign |
Het |
| Or2b2b |
A |
T |
13: 21,859,015 (GRCm39) |
V33E |
probably benign |
Het |
| Or8s16 |
T |
A |
15: 98,211,186 (GRCm39) |
N82Y |
possibly damaging |
Het |
| Oxct2a |
G |
T |
4: 123,216,441 (GRCm39) |
D313E |
probably damaging |
Het |
| Pcdha2 |
T |
A |
18: 37,073,546 (GRCm39) |
H392Q |
probably benign |
Het |
| Pcdhb20 |
T |
G |
18: 37,639,799 (GRCm39) |
L775R |
probably benign |
Het |
| Pclo |
A |
G |
5: 14,840,408 (GRCm39) |
D1449G |
|
Het |
| Pcx |
A |
G |
19: 4,651,970 (GRCm39) |
T73A |
probably benign |
Het |
| Pou6f2 |
A |
G |
13: 18,314,189 (GRCm39) |
S395P |
probably benign |
Het |
| Prss35 |
C |
G |
9: 86,638,392 (GRCm39) |
I387M |
|
Het |
| Radil |
C |
A |
5: 142,471,220 (GRCm39) |
D1019Y |
probably damaging |
Het |
| Rnf40 |
G |
T |
7: 127,191,010 (GRCm39) |
|
probably null |
Het |
| Scarb1 |
A |
T |
5: 125,417,891 (GRCm39) |
L19Q |
probably damaging |
Het |
| Scn8a |
T |
A |
15: 100,930,159 (GRCm39) |
F1457I |
|
Het |
| Sdk2 |
C |
T |
11: 113,760,744 (GRCm39) |
V339I |
possibly damaging |
Het |
| Siglec1 |
A |
G |
2: 130,916,404 (GRCm39) |
L1182P |
probably damaging |
Het |
| Slc4a4 |
G |
A |
5: 89,194,131 (GRCm39) |
V204I |
probably damaging |
Het |
| Sp9 |
T |
C |
2: 73,104,243 (GRCm39) |
S266P |
probably benign |
Het |
| Spata21 |
A |
G |
4: 140,831,316 (GRCm39) |
E421G |
probably damaging |
Het |
| Sulf1 |
C |
T |
1: 12,929,459 (GRCm39) |
P242L |
probably damaging |
Het |
| Sval3 |
G |
A |
6: 41,945,105 (GRCm39) |
G11E |
possibly damaging |
Het |
| Tecta |
T |
A |
9: 42,248,576 (GRCm39) |
Y1942F |
probably damaging |
Het |
| Thbs2 |
C |
T |
17: 14,890,243 (GRCm39) |
G1121D |
probably damaging |
Het |
| Thrap3 |
G |
T |
4: 126,070,048 (GRCm39) |
S613* |
probably null |
Het |
| Ttc34 |
A |
C |
4: 154,942,539 (GRCm39) |
K59Q |
probably damaging |
Het |
| Tut7 |
A |
T |
13: 59,929,957 (GRCm39) |
L1428H |
possibly damaging |
Het |
| Ube4b |
A |
T |
4: 149,444,748 (GRCm39) |
L504Q |
probably damaging |
Het |
| Uncx |
A |
T |
5: 139,529,771 (GRCm39) |
E8V |
probably damaging |
Het |
| Vmn1r79 |
A |
T |
7: 11,910,261 (GRCm39) |
I48F |
probably damaging |
Het |
| Vmn2r99 |
C |
A |
17: 19,598,388 (GRCm39) |
Y137* |
probably null |
Het |
| Zfp354b |
G |
A |
11: 50,814,523 (GRCm39) |
T134I |
probably benign |
Het |
| Zfp618 |
G |
A |
4: 63,051,510 (GRCm39) |
V764I |
possibly damaging |
Het |
| Zfp873 |
T |
G |
10: 81,897,131 (GRCm39) |
C621G |
probably benign |
Het |
|
| Other mutations in N4bp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:N4bp2
|
APN |
5 |
65,964,867 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01503:N4bp2
|
APN |
5 |
65,960,890 (GRCm39) |
nonsense |
probably null |
0.00 |
|
IGL01621:N4bp2
|
APN |
5 |
65,948,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02109:N4bp2
|
APN |
5 |
65,955,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02286:N4bp2
|
APN |
5 |
65,960,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
1mM(1):N4bp2
|
UTSW |
5 |
65,965,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03046:N4bp2
|
UTSW |
5 |
65,948,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0164:N4bp2
|
UTSW |
5 |
65,960,916 (GRCm39) |
splice site |
probably benign |
|
|
R0285:N4bp2
|
UTSW |
5 |
65,963,902 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0366:N4bp2
|
UTSW |
5 |
65,963,739 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0548:N4bp2
|
UTSW |
5 |
65,965,496 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0551:N4bp2
|
UTSW |
5 |
65,977,684 (GRCm39) |
splice site |
probably null |
|
|
R0671:N4bp2
|
UTSW |
5 |
65,964,780 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1136:N4bp2
|
UTSW |
5 |
65,965,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1515:N4bp2
|
UTSW |
5 |
65,947,841 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1597:N4bp2
|
UTSW |
5 |
65,964,483 (GRCm39) |
missense |
probably benign |
0.45 |
|
R1628:N4bp2
|
UTSW |
5 |
65,960,915 (GRCm39) |
splice site |
probably null |
|
|
R1722:N4bp2
|
UTSW |
5 |
65,964,225 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1735:N4bp2
|
UTSW |
5 |
65,965,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1745:N4bp2
|
UTSW |
5 |
65,948,165 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1759:N4bp2
|
UTSW |
5 |
65,983,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1799:N4bp2
|
UTSW |
5 |
65,964,168 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1846:N4bp2
|
UTSW |
5 |
65,965,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1872:N4bp2
|
UTSW |
5 |
65,951,861 (GRCm39) |
splice site |
probably benign |
|
|
R2042:N4bp2
|
UTSW |
5 |
65,983,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2082:N4bp2
|
UTSW |
5 |
65,964,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:N4bp2
|
UTSW |
5 |
65,948,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2147:N4bp2
|
UTSW |
5 |
65,966,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2251:N4bp2
|
UTSW |
5 |
65,964,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2507:N4bp2
|
UTSW |
5 |
65,947,404 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2508:N4bp2
|
UTSW |
5 |
65,947,404 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2919:N4bp2
|
UTSW |
5 |
65,964,441 (GRCm39) |
missense |
probably benign |
0.22 |
|
R3086:N4bp2
|
UTSW |
5 |
65,948,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4092:N4bp2
|
UTSW |
5 |
65,947,799 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4177:N4bp2
|
UTSW |
5 |
65,955,513 (GRCm39) |
splice site |
probably null |
|
|
R4718:N4bp2
|
UTSW |
5 |
65,960,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4859:N4bp2
|
UTSW |
5 |
65,982,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4863:N4bp2
|
UTSW |
5 |
65,965,473 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4915:N4bp2
|
UTSW |
5 |
65,960,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4949:N4bp2
|
UTSW |
5 |
65,979,142 (GRCm39) |
splice site |
probably null |
|
|
R4978:N4bp2
|
UTSW |
5 |
65,947,583 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5029:N4bp2
|
UTSW |
5 |
65,972,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5079:N4bp2
|
UTSW |
5 |
65,969,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5097:N4bp2
|
UTSW |
5 |
65,974,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5158:N4bp2
|
UTSW |
5 |
65,965,805 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5228:N4bp2
|
UTSW |
5 |
65,964,861 (GRCm39) |
missense |
probably benign |
|
|
R5322:N4bp2
|
UTSW |
5 |
65,947,800 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5554:N4bp2
|
UTSW |
5 |
65,965,457 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5731:N4bp2
|
UTSW |
5 |
65,966,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5840:N4bp2
|
UTSW |
5 |
65,965,437 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6393:N4bp2
|
UTSW |
5 |
65,948,344 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6767:N4bp2
|
UTSW |
5 |
65,974,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7103:N4bp2
|
UTSW |
5 |
65,964,189 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7112:N4bp2
|
UTSW |
5 |
65,948,050 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R7171:N4bp2
|
UTSW |
5 |
65,965,365 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7177:N4bp2
|
UTSW |
5 |
65,964,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7240:N4bp2
|
UTSW |
5 |
65,951,888 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7353:N4bp2
|
UTSW |
5 |
65,963,714 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7450:N4bp2
|
UTSW |
5 |
65,982,643 (GRCm39) |
nonsense |
probably null |
|
|
R7560:N4bp2
|
UTSW |
5 |
65,948,458 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7698:N4bp2
|
UTSW |
5 |
65,965,500 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7743:N4bp2
|
UTSW |
5 |
65,965,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7871:N4bp2
|
UTSW |
5 |
65,964,446 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7981:N4bp2
|
UTSW |
5 |
65,969,485 (GRCm39) |
missense |
probably benign |
0.41 |
|
R8065:N4bp2
|
UTSW |
5 |
65,964,639 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8067:N4bp2
|
UTSW |
5 |
65,964,639 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8164:N4bp2
|
UTSW |
5 |
65,966,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8166:N4bp2
|
UTSW |
5 |
65,977,655 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8331:N4bp2
|
UTSW |
5 |
65,964,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8559:N4bp2
|
UTSW |
5 |
65,982,628 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R8806:N4bp2
|
UTSW |
5 |
65,965,551 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9287:N4bp2
|
UTSW |
5 |
65,960,855 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9369:N4bp2
|
UTSW |
5 |
65,964,259 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9460:N4bp2
|
UTSW |
5 |
65,963,886 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9605:N4bp2
|
UTSW |
5 |
65,963,879 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9641:N4bp2
|
UTSW |
5 |
65,948,035 (GRCm39) |
missense |
probably benign |
0.15 |
|
Z1177:N4bp2
|
UTSW |
5 |
65,964,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTCTGTACAGAGCACGAGC -3'
(R):5'- GCGGCTTGAAATTGAACCCTTC -3'
Sequencing Primer
(F):5'- GCTCAAACAGCGAAACTCTCAAGAG -3'
(R):5'- GCTTGAAATTGAACCCTTCAGAGG -3'
|
| Posted On |
2022-06-15 |
Incidental Mutation