Incidental Mutation 'R9475:Ugt1a10'
| ID |
715679 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ugt1a10
|
| Ensembl Gene |
ENSMUSG00000090165 |
| Gene Name |
UDP glycosyltransferase 1 family, polypeptide A10 |
| Synonyms |
A13 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.115)
|
| Stock # |
R9475 (G1)
|
| Quality Score |
95.0077 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
88055388-88219004 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 88216260 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Cysteine
at position 201
(R201C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000134443
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014263]
[ENSMUST00000049289]
[ENSMUST00000058237]
[ENSMUST00000073049]
[ENSMUST00000073772]
[ENSMUST00000097659]
[ENSMUST00000113134]
[ENSMUST00000113135]
[ENSMUST00000113137]
[ENSMUST00000113138]
[ENSMUST00000113139]
[ENSMUST00000113142]
[ENSMUST00000138182]
[ENSMUST00000140092]
[ENSMUST00000150634]
[ENSMUST00000173325]
[ENSMUST00000126203]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000014263
AA Change: R401C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000014263
Gene: ENSMUSG00000054545
AA Change: R401C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
27 |
522 |
1.2e-229 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
363 |
448 |
1e-8 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000049289
AA Change: R403C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000037258
Gene: ENSMUSG00000090171
AA Change: R403C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
28 |
524 |
2.2e-247 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
363 |
452 |
4.5e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000058237
AA Change: R401C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000058683
Gene: ENSMUSG00000090124
AA Change: R401C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
522 |
1.5e-234 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
361 |
450 |
4.5e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000073049
AA Change: R405C
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000072803
Gene: ENSMUSG00000089960
AA Change: R405C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
29 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
30 |
526 |
5.8e-241 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
365 |
454 |
4.5e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000073772
AA Change: R398C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000073444
Gene: ENSMUSG00000090175
AA Change: R398C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
24 |
519 |
2.3e-232 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
358 |
447 |
4.5e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000097659
AA Change: R399C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000095263
Gene: ENSMUSG00000089943
AA Change: R399C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
24 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
25 |
520 |
6.7e-246 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
359 |
448 |
1.3e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113134
AA Change: R401C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108759
Gene: ENSMUSG00000054545
AA Change: R401C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
27 |
522 |
2.7e-232 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
361 |
450 |
4.5e-9 |
PFAM |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000108760
Gene: ENSMUSG00000090124
AA Change: R401C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
27 |
522 |
1.2e-229 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
363 |
448 |
1e-8 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113137
AA Change: R401C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108762
Gene: ENSMUSG00000090145
AA Change: R401C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
27 |
522 |
1.3e-231 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
361 |
450 |
2.8e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113138
AA Change: R401C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108763
Gene: ENSMUSG00000090145
AA Change: R401C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
27 |
522 |
7.3e-229 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
363 |
448 |
6.6e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113139
AA Change: R400C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108764
Gene: ENSMUSG00000089675
AA Change: R400C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
521 |
3.6e-237 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
360 |
449 |
1.3e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113142
AA Change: R400C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108767
Gene: ENSMUSG00000090165
AA Change: R400C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
521 |
7.3e-231 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
360 |
449 |
1.3e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000138182
AA Change: R176C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000119985
Gene: ENSMUSG00000090165
AA Change: R176C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
62 |
7e-11 |
PFAM |
|
Pfam:UDPGT
|
58 |
207 |
1.9e-90 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
137 |
207 |
4.8e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000140092
AA Change: R135C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000115642
Gene: ENSMUSG00000054545
AA Change: R135C
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:UDPGT
|
1 |
166 |
9.3e-98 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
96 |
166 |
4.9e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000150634
AA Change: R176C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000123452
Gene: ENSMUSG00000090124
AA Change: R176C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
62 |
9.5e-11 |
PFAM |
|
Pfam:UDPGT
|
58 |
207 |
2e-90 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
137 |
207 |
4.8e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000173325
AA Change: R201C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000134443
Gene: ENSMUSG00000090165
AA Change: R201C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
61 |
3.4e-10 |
PFAM |
|
Pfam:UDPGT
|
59 |
210 |
8.9e-92 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173165
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000174821
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124852
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000126203
|
| SMART Domains |
Protein: ENSMUSP00000116653
Gene: ENSMUSG00000090124
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
62 |
4.6e-11 |
PFAM |
|
Pfam:UDPGT
|
59 |
127 |
8.9e-24 |
PFAM |
|
| Meta Mutation Damage Score |
0.8935 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.5%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 64 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc6 |
A |
T |
7: 46,016,468 (GRCm38) |
W243R |
probably damaging |
Het |
| Ablim1 |
T |
G |
19: 57,239,180 (GRCm38) |
K18Q |
probably benign |
Het |
| Adamts18 |
T |
A |
8: 113,777,938 (GRCm38) |
N174Y |
possibly damaging |
Het |
| Agbl2 |
A |
G |
2: 90,784,093 (GRCm38) |
H23R |
probably benign |
Het |
| Akap6 |
T |
G |
12: 53,010,552 (GRCm38) |
Y934D |
probably damaging |
Het |
| Alas1 |
C |
T |
9: 106,234,062 (GRCm38) |
S635N |
probably benign |
Het |
| Ankrd24 |
A |
G |
10: 81,642,299 (GRCm38) |
|
probably null |
Het |
| Atp6v0a4 |
A |
G |
6: 38,060,982 (GRCm38) |
L560P |
probably damaging |
Het |
| Cacng1 |
C |
T |
11: 107,716,292 (GRCm38) |
V34M |
possibly damaging |
Het |
| Clcn3 |
C |
T |
8: 60,934,517 (GRCm38) |
A233T |
probably damaging |
Het |
| Cntnap3 |
A |
G |
13: 64,799,135 (GRCm38) |
F160S |
probably damaging |
Het |
| Ctnnd2 |
A |
G |
15: 30,881,130 (GRCm38) |
S719G |
probably damaging |
Het |
| Exosc2 |
G |
A |
2: 31,674,743 (GRCm38) |
V107I |
probably benign |
Het |
| Fam83b |
C |
A |
9: 76,491,803 (GRCm38) |
V673F |
probably benign |
Het |
| Fras1 |
T |
C |
5: 96,780,070 (GRCm38) |
F3781L |
probably damaging |
Het |
| Gal3st1 |
T |
A |
11: 3,998,660 (GRCm38) |
L289H |
probably damaging |
Het |
| Garem1 |
T |
C |
18: 21,148,313 (GRCm38) |
I329V |
probably benign |
Het |
| Gli3 |
G |
A |
13: 15,725,711 (GRCm38) |
G1228S |
possibly damaging |
Het |
| Gpbp1l1 |
T |
C |
4: 116,574,361 (GRCm38) |
F72S |
possibly damaging |
Het |
| Hao1 |
T |
A |
2: 134,548,261 (GRCm38) |
M53L |
probably benign |
Het |
| Hjurp |
CTCTGGGAGGGCTTGCTCCGGGGGCAGTGTGTCCTGTTCTTGTGCAGCCCCT |
C |
1: 88,266,277 (GRCm38) |
|
probably benign |
Het |
| Iqcm |
A |
G |
8: 75,753,455 (GRCm38) |
E347G |
probably damaging |
Het |
| Itpr3 |
G |
A |
17: 27,118,677 (GRCm38) |
|
probably benign |
Het |
| Kcnrg |
A |
G |
14: 61,607,657 (GRCm38) |
I49V |
possibly damaging |
Het |
| Lrrc8e |
G |
A |
8: 4,235,346 (GRCm38) |
G524S |
probably benign |
Het |
| Lrrn1 |
A |
T |
6: 107,568,300 (GRCm38) |
Y353F |
probably damaging |
Het |
| Mdn1 |
A |
G |
4: 32,739,849 (GRCm38) |
D3701G |
possibly damaging |
Het |
| Mtmr2 |
A |
G |
9: 13,805,471 (GRCm38) |
T623A |
probably benign |
Het |
| Ndst4 |
C |
A |
3: 125,714,647 (GRCm38) |
S287* |
probably null |
Het |
| Ntrk3 |
A |
C |
7: 78,302,732 (GRCm38) |
M579R |
probably benign |
Het |
| Oas1a |
G |
A |
5: 120,899,254 (GRCm38) |
L237F |
probably damaging |
Het |
| Olfr1350 |
A |
T |
7: 6,570,819 (GRCm38) |
Y276F |
probably damaging |
Het |
| Olfr169 |
T |
C |
16: 19,566,520 (GRCm38) |
D121G |
probably benign |
Het |
| Olfr857 |
T |
C |
9: 19,713,643 (GRCm38) |
M272T |
probably benign |
Het |
| Paqr5 |
T |
A |
9: 61,956,225 (GRCm38) |
I272F |
probably damaging |
Het |
| Pcdha11 |
T |
A |
18: 37,007,538 (GRCm38) |
V740E |
probably damaging |
Het |
| Pdgfra |
A |
C |
5: 75,167,927 (GRCm38) |
N240T |
possibly damaging |
Het |
| Plbd2 |
G |
A |
5: 120,494,380 (GRCm38) |
Q186* |
probably null |
Het |
| Plce1 |
G |
A |
19: 38,777,893 (GRCm38) |
E2121K |
possibly damaging |
Het |
| Ppargc1a |
C |
A |
5: 51,495,738 (GRCm38) |
G161C |
probably damaging |
Het |
| Ptprk |
T |
C |
10: 28,334,480 (GRCm38) |
I166T |
possibly damaging |
Het |
| Rhox8 |
GCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCT |
GCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCT |
X: 37,878,114 (GRCm38) |
|
probably benign |
Het |
| Rpap2 |
T |
A |
5: 107,620,589 (GRCm38) |
L431Q |
probably damaging |
Het |
| Rslcan18 |
T |
A |
13: 67,102,064 (GRCm38) |
K160* |
probably null |
Het |
| Sema7a |
T |
C |
9: 57,954,905 (GRCm38) |
F180L |
probably benign |
Het |
| Sh2d3c |
C |
T |
2: 32,753,027 (GRCm38) |
L741F |
probably damaging |
Het |
| Shank1 |
G |
A |
7: 44,312,918 (GRCm38) |
S71N |
unknown |
Het |
| Skint6 |
C |
T |
4: 112,806,840 (GRCm38) |
|
probably null |
Het |
| Skiv2l |
A |
T |
17: 34,841,102 (GRCm38) |
D897E |
probably benign |
Het |
| Slc35f3 |
T |
C |
8: 126,382,254 (GRCm38) |
S181P |
probably damaging |
Het |
| Slc4a9 |
A |
T |
18: 36,529,216 (GRCm38) |
E127V |
probably null |
Het |
| Spata5 |
T |
C |
3: 37,431,909 (GRCm38) |
V260A |
probably benign |
Het |
| Speg |
C |
T |
1: 75,388,091 (GRCm38) |
T372I |
probably damaging |
Het |
| Syce1l |
A |
G |
8: 113,655,103 (GRCm38) |
T204A |
probably benign |
Het |
| Tas2r138 |
T |
A |
6: 40,612,458 (GRCm38) |
M285L |
probably benign |
Het |
| Tbc1d10a |
G |
C |
11: 4,213,604 (GRCm38) |
K285N |
probably damaging |
Het |
| Trim9 |
T |
A |
12: 70,346,454 (GRCm38) |
M239L |
probably benign |
Het |
| Trp53bp1 |
A |
G |
2: 121,209,280 (GRCm38) |
S1293P |
probably benign |
Het |
| Uaca |
C |
T |
9: 60,872,216 (GRCm38) |
T1295M |
possibly damaging |
Het |
| Ubald1 |
G |
T |
16: 4,875,569 (GRCm38) |
Q161K |
possibly damaging |
Het |
| Vps45 |
T |
G |
3: 96,042,925 (GRCm38) |
T231P |
probably damaging |
Het |
| Wdr17 |
A |
T |
8: 54,635,477 (GRCm38) |
D1186E |
probably benign |
Het |
| Zfp534 |
G |
A |
4: 147,682,274 (GRCm38) |
T8I |
probably benign |
Het |
| Zfp68 |
T |
C |
5: 138,607,255 (GRCm38) |
N269D |
probably benign |
Het |
|
| Other mutations in Ugt1a10 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01126:Ugt1a10
|
APN |
1 |
88,055,987 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
IGL02219:Ugt1a10
|
APN |
1 |
88,056,058 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02511:Ugt1a10
|
APN |
1 |
88,055,863 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02990:Ugt1a10
|
APN |
1 |
88,055,879 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4142001:Ugt1a10
|
UTSW |
1 |
88,216,158 (GRCm38) |
small deletion |
probably benign |
|
|
R0201:Ugt1a10
|
UTSW |
1 |
88,218,249 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0201:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0522:Ugt1a10
|
UTSW |
1 |
88,218,249 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0525:Ugt1a10
|
UTSW |
1 |
88,218,249 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0554:Ugt1a10
|
UTSW |
1 |
88,056,095 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0748:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0811:Ugt1a10
|
UTSW |
1 |
88,056,182 (GRCm38) |
missense |
probably benign |
0.33 |
|
R0812:Ugt1a10
|
UTSW |
1 |
88,056,182 (GRCm38) |
missense |
probably benign |
0.33 |
|
R1129:Ugt1a10
|
UTSW |
1 |
88,055,609 (GRCm38) |
missense |
probably benign |
|
|
R1207:Ugt1a10
|
UTSW |
1 |
88,216,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1432:Ugt1a10
|
UTSW |
1 |
88,216,260 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1457:Ugt1a10
|
UTSW |
1 |
88,055,711 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1469:Ugt1a10
|
UTSW |
1 |
88,216,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1972:Ugt1a10
|
UTSW |
1 |
88,056,047 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1973:Ugt1a10
|
UTSW |
1 |
88,056,047 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2039:Ugt1a10
|
UTSW |
1 |
88,055,981 (GRCm38) |
missense |
probably benign |
0.32 |
|
R2307:Ugt1a10
|
UTSW |
1 |
88,055,947 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3952:Ugt1a10
|
UTSW |
1 |
88,216,140 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3973:Ugt1a10
|
UTSW |
1 |
88,216,140 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4232:Ugt1a10
|
UTSW |
1 |
88,056,210 (GRCm38) |
missense |
probably benign |
0.39 |
|
R4392:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4393:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4402:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4417:Ugt1a10
|
UTSW |
1 |
88,055,995 (GRCm38) |
missense |
probably benign |
|
|
R4474:Ugt1a10
|
UTSW |
1 |
88,215,928 (GRCm38) |
intron |
probably benign |
|
|
R4476:Ugt1a10
|
UTSW |
1 |
88,215,928 (GRCm38) |
intron |
probably benign |
|
|
R4515:Ugt1a10
|
UTSW |
1 |
88,056,197 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4579:Ugt1a10
|
UTSW |
1 |
88,056,116 (GRCm38) |
missense |
probably benign |
|
|
R4582:Ugt1a10
|
UTSW |
1 |
88,055,741 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R4609:Ugt1a10
|
UTSW |
1 |
88,055,482 (GRCm38) |
start codon destroyed |
possibly damaging |
0.92 |
|
R4627:Ugt1a10
|
UTSW |
1 |
88,218,390 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4790:Ugt1a10
|
UTSW |
1 |
88,056,287 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4799:Ugt1a10
|
UTSW |
1 |
88,215,928 (GRCm38) |
intron |
probably benign |
|
|
R4910:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4915:Ugt1a10
|
UTSW |
1 |
88,055,924 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5110:Ugt1a10
|
UTSW |
1 |
88,056,252 (GRCm38) |
splice site |
probably null |
|
|
R5168:Ugt1a10
|
UTSW |
1 |
88,055,809 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5329:Ugt1a10
|
UTSW |
1 |
88,216,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5373:Ugt1a10
|
UTSW |
1 |
88,055,910 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5374:Ugt1a10
|
UTSW |
1 |
88,055,910 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5615:Ugt1a10
|
UTSW |
1 |
88,216,158 (GRCm38) |
small deletion |
probably benign |
|
|
R6498:Ugt1a10
|
UTSW |
1 |
88,216,140 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6727:Ugt1a10
|
UTSW |
1 |
88,056,257 (GRCm38) |
splice site |
probably null |
|
|
R6809:Ugt1a10
|
UTSW |
1 |
88,055,925 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6924:Ugt1a10
|
UTSW |
1 |
88,055,657 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6967:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7913:Ugt1a10
|
UTSW |
1 |
88,055,755 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9165:Ugt1a10
|
UTSW |
1 |
88,055,787 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9264:Ugt1a10
|
UTSW |
1 |
88,055,671 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
S24628:Ugt1a10
|
UTSW |
1 |
88,216,158 (GRCm38) |
small deletion |
probably benign |
|
|
X0013:Ugt1a10
|
UTSW |
1 |
88,216,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Ugt1a10
|
UTSW |
1 |
88,055,842 (GRCm38) |
missense |
probably benign |
0.20 |
|
Z1190:Ugt1a10
|
UTSW |
1 |
88,216,158 (GRCm38) |
small deletion |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCACCCCAATTTTCTACAATGG -3'
(R):5'- TGCTGTAGGTATGAATACAAGTAGG -3'
Sequencing Primer
(F):5'- GGGGTATTCTCAGAATCCAGACTC -3'
(R):5'- CCTACCTCTTGTTGTTGATG -3'
|
| Posted On |
2022-06-15 |
Incidental Mutation