Incidental Mutation 'R9484:Dock9'
| ID |
716481 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dock9
|
| Ensembl Gene |
ENSMUSG00000025558 |
| Gene Name |
dedicator of cytokinesis 9 |
| Synonyms |
D14Wsu89e, Zizimin1, B230309H04Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9484 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
121542046-121797837 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 121581432 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glycine
at position 1546
(V1546G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000148834
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040700]
[ENSMUST00000100299]
[ENSMUST00000212181]
[ENSMUST00000212376]
[ENSMUST00000212416]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000040700
AA Change: V1545G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000047881
Gene: ENSMUSG00000025558
AA Change: V1545G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3398
|
58 |
151 |
5.6e-36 |
PFAM |
|
PH
|
172 |
280 |
1.38e-16 |
SMART |
|
Blast:PH
|
297 |
372 |
4e-25 |
BLAST |
|
Pfam:DOCK-C2
|
631 |
822 |
5.3e-51 |
PFAM |
|
Pfam:DHR-2
|
1523 |
2068 |
2.1e-212 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000100299
AA Change: V1516G
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000097872
Gene: ENSMUSG00000025558
AA Change: V1516G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3398
|
58 |
153 |
1.5e-32 |
PFAM |
|
PH
|
174 |
282 |
1.38e-16 |
SMART |
|
Blast:PH
|
299 |
374 |
4e-25 |
BLAST |
|
Pfam:DOCK-C2
|
632 |
825 |
1.3e-59 |
PFAM |
|
low complexity region
|
1752 |
1763 |
N/A |
INTRINSIC |
|
Pfam:Ded_cyto
|
1836 |
2013 |
2.4e-69 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000212181
AA Change: V1546G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000212376
AA Change: V1536G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212416
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.8%
- 10x: 99.2%
- 20x: 97.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acads |
A |
T |
5: 115,112,786 (GRCm38) |
C151S |
probably damaging |
Het |
| Actr8 |
T |
C |
14: 29,986,344 (GRCm38) |
I193T |
probably benign |
Het |
| Btbd2 |
T |
C |
10: 80,644,269 (GRCm38) |
N419S |
probably benign |
Het |
| Cacna2d1 |
T |
A |
5: 16,356,833 (GRCm38) |
W821R |
probably damaging |
Het |
| Cadps2 |
T |
C |
6: 23,626,647 (GRCm38) |
Y214C |
probably benign |
Het |
| Calu |
T |
A |
6: 29,366,163 (GRCm38) |
L180Q |
probably damaging |
Het |
| Corin |
C |
T |
5: 72,339,937 (GRCm38) |
V615I |
probably damaging |
Het |
| Cyp8b1 |
A |
T |
9: 121,915,917 (GRCm38) |
D116E |
probably benign |
Het |
| D630036H23Rik |
C |
A |
12: 36,381,712 (GRCm38) |
A96S |
unknown |
Het |
| Ddx24 |
A |
T |
12: 103,411,296 (GRCm38) |
Y717N |
probably damaging |
Het |
| Dmap1 |
G |
T |
4: 117,676,111 (GRCm38) |
Q249K |
probably benign |
Het |
| Dnah10 |
T |
A |
5: 124,823,444 (GRCm38) |
W3922R |
probably damaging |
Het |
| Dnah14 |
T |
C |
1: 181,690,208 (GRCm38) |
F2036L |
probably benign |
Het |
| Dnah14 |
T |
C |
1: 181,797,746 (GRCm38) |
I4064T |
probably benign |
Het |
| Eif3a |
A |
T |
19: 60,766,568 (GRCm38) |
S1059T |
unknown |
Het |
| Ep300 |
A |
G |
15: 81,636,825 (GRCm38) |
E1262G |
unknown |
Het |
| Evl |
T |
A |
12: 108,686,457 (GRCm38) |
I387N |
probably damaging |
Het |
| Fat2 |
A |
C |
11: 55,309,926 (GRCm38) |
V774G |
probably damaging |
Het |
| Fez1 |
T |
A |
9: 36,843,797 (GRCm38) |
Y31N |
probably benign |
Het |
| Fkbp10 |
A |
G |
11: 100,423,134 (GRCm38) |
I435V |
probably damaging |
Het |
| Flnb |
A |
G |
14: 7,929,004 (GRCm38) |
D1911G |
probably benign |
Het |
| Fnbp1 |
T |
C |
2: 31,083,026 (GRCm38) |
Y154C |
probably benign |
Het |
| Fndc10 |
T |
C |
4: 155,695,039 (GRCm38) |
I180T |
possibly damaging |
Het |
| Frmd4a |
G |
A |
2: 4,604,215 (GRCm38) |
V965I |
possibly damaging |
Het |
| Gabrr2 |
A |
G |
4: 33,071,352 (GRCm38) |
H64R |
possibly damaging |
Het |
| Glis3 |
T |
C |
19: 28,531,003 (GRCm38) |
D527G |
probably damaging |
Het |
| Gm2022 |
A |
T |
12: 87,895,479 (GRCm38) |
Q37L |
possibly damaging |
Het |
| H2-Ob |
T |
A |
17: 34,241,015 (GRCm38) |
F33L |
probably damaging |
Het |
| Hbb-bh1 |
C |
T |
7: 103,843,032 (GRCm38) |
E27K |
probably benign |
Het |
| Ifnb1 |
T |
A |
4: 88,522,678 (GRCm38) |
T33S |
probably benign |
Het |
| Igkv4-80 |
T |
A |
6: 69,016,782 (GRCm38) |
T42S |
probably damaging |
Het |
| Irs2 |
C |
T |
8: 11,007,334 (GRCm38) |
G366D |
probably damaging |
Het |
| Kcnk2 |
CAAA |
CAA |
1: 189,256,694 (GRCm38) |
|
probably null |
Het |
| Krtap5-3 |
T |
A |
7: 142,202,331 (GRCm38) |
C302S |
unknown |
Het |
| Lgi1 |
A |
G |
19: 38,306,309 (GRCm38) |
K510E |
probably benign |
Het |
| Lgi2 |
T |
A |
5: 52,538,594 (GRCm38) |
D341V |
probably benign |
Het |
| Lin7c |
T |
C |
2: 109,894,468 (GRCm38) |
I14T |
probably benign |
Het |
| Lrrc19 |
A |
T |
4: 94,643,336 (GRCm38) |
M13K |
probably benign |
Het |
| Lrrc69 |
T |
C |
4: 14,666,012 (GRCm38) |
I315M |
probably benign |
Het |
| Myo5c |
A |
T |
9: 75,297,488 (GRCm38) |
D1541V |
probably damaging |
Het |
| Mypn |
T |
G |
10: 63,167,240 (GRCm38) |
M373L |
probably benign |
Het |
| Nckipsd |
C |
A |
9: 108,812,638 (GRCm38) |
H333N |
probably damaging |
Het |
| Nrg2 |
A |
T |
18: 36,024,348 (GRCm38) |
L428Q |
probably null |
Het |
| Olfr1367 |
C |
A |
13: 21,347,417 (GRCm38) |
T163K |
probably damaging |
Het |
| Olfr235 |
T |
C |
19: 12,268,371 (GRCm38) |
I47T |
possibly damaging |
Het |
| Olfr53 |
T |
C |
7: 140,651,991 (GRCm38) |
L4S |
probably benign |
Het |
| Otogl |
C |
T |
10: 107,901,295 (GRCm38) |
G86D |
probably damaging |
Het |
| Otogl |
T |
A |
10: 107,822,033 (GRCm38) |
|
probably null |
Het |
| Papln |
A |
T |
12: 83,791,844 (GRCm38) |
Q1249L |
probably benign |
Het |
| Plxna2 |
G |
T |
1: 194,644,894 (GRCm38) |
G379C |
probably damaging |
Het |
| Pofut2 |
T |
C |
10: 77,259,426 (GRCm38) |
I35T |
probably benign |
Het |
| Pros1 |
A |
G |
16: 62,924,524 (GRCm38) |
T501A |
possibly damaging |
Het |
| Rapgef1 |
T |
C |
2: 29,735,809 (GRCm38) |
S1042P |
possibly damaging |
Het |
| Rps6kb1 |
C |
T |
11: 86,517,617 (GRCm38) |
E185K |
probably damaging |
Het |
| Slc13a2 |
A |
T |
11: 78,403,407 (GRCm38) |
L216Q |
probably damaging |
Het |
| Slc22a14 |
T |
C |
9: 119,180,549 (GRCm38) |
Y160C |
probably damaging |
Het |
| Slc22a4 |
T |
A |
11: 53,988,947 (GRCm38) |
I429F |
possibly damaging |
Het |
| Slc26a3 |
A |
G |
12: 31,461,786 (GRCm38) |
K457E |
probably damaging |
Het |
| Slc47a2 |
T |
C |
11: 61,336,234 (GRCm38) |
I169M |
possibly damaging |
Het |
| Slco1a1 |
C |
T |
6: 141,908,946 (GRCm38) |
V660I |
probably benign |
Het |
| Smyd1 |
A |
G |
6: 71,225,466 (GRCm38) |
Y252H |
probably damaging |
Het |
| Soga3 |
G |
A |
10: 29,196,973 (GRCm38) |
D754N |
probably damaging |
Het |
| Spp2 |
A |
T |
1: 88,406,973 (GRCm38) |
|
probably benign |
Het |
| Stra8 |
T |
A |
6: 34,934,186 (GRCm38) |
W250R |
probably damaging |
Het |
| Syne1 |
A |
C |
10: 5,220,359 (GRCm38) |
L5183R |
probably damaging |
Het |
| Tdrd9 |
T |
C |
12: 112,046,250 (GRCm38) |
S1203P |
probably damaging |
Het |
| Th |
C |
A |
7: 142,899,883 (GRCm38) |
E27* |
probably null |
Het |
| Thada |
C |
A |
17: 84,429,191 (GRCm38) |
L887F |
probably damaging |
Het |
| Timm23 |
T |
C |
14: 32,180,629 (GRCm38) |
T186A |
probably benign |
Het |
| Tmem132b |
A |
T |
5: 125,783,356 (GRCm38) |
E555V |
probably damaging |
Het |
| Tnik |
A |
T |
3: 28,594,944 (GRCm38) |
Q457L |
unknown |
Het |
| Uba7 |
C |
A |
9: 107,983,838 (GRCm38) |
H942Q |
probably benign |
Het |
| Upf2 |
T |
C |
2: 5,961,267 (GRCm38) |
S233P |
unknown |
Het |
| Urm1 |
T |
A |
2: 29,842,748 (GRCm38) |
N72K |
probably damaging |
Het |
| Usp10 |
T |
C |
8: 119,948,765 (GRCm38) |
S508P |
possibly damaging |
Het |
| Usp37 |
G |
A |
1: 74,459,922 (GRCm38) |
P632S |
probably damaging |
Het |
| Wdr77 |
T |
A |
3: 105,965,088 (GRCm38) |
N209K |
probably benign |
Het |
| Zbtb24 |
C |
T |
10: 41,451,433 (GRCm38) |
T105M |
probably benign |
Het |
| Zfp341 |
T |
A |
2: 154,643,843 (GRCm38) |
I671N |
probably damaging |
Het |
| Zfp414 |
A |
G |
17: 33,630,010 (GRCm38) |
T73A |
probably benign |
Het |
| Zfp574 |
A |
T |
7: 25,081,979 (GRCm38) |
I809F |
possibly damaging |
Het |
| Zfp62 |
T |
C |
11: 49,217,281 (GRCm38) |
I733T |
probably damaging |
Het |
| Zfp719 |
A |
G |
7: 43,590,157 (GRCm38) |
I390V |
possibly damaging |
Het |
|
| Other mutations in Dock9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Dock9
|
APN |
14 |
121,668,468 (GRCm38) |
missense |
probably benign |
0.12 |
|
IGL00817:Dock9
|
APN |
14 |
121,698,291 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL00923:Dock9
|
APN |
14 |
121,607,092 (GRCm38) |
unclassified |
probably benign |
|
|
IGL01385:Dock9
|
APN |
14 |
121,580,583 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01567:Dock9
|
APN |
14 |
121,653,084 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01767:Dock9
|
APN |
14 |
121,622,870 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
IGL01811:Dock9
|
APN |
14 |
121,559,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02512:Dock9
|
APN |
14 |
121,619,538 (GRCm38) |
splice site |
probably benign |
|
|
IGL02525:Dock9
|
APN |
14 |
121,640,126 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02550:Dock9
|
APN |
14 |
121,698,312 (GRCm38) |
start codon destroyed |
probably null |
0.07 |
|
IGL02559:Dock9
|
APN |
14 |
121,625,147 (GRCm38) |
splice site |
probably benign |
|
|
IGL02666:Dock9
|
APN |
14 |
121,580,699 (GRCm38) |
missense |
probably benign |
0.42 |
|
IGL02674:Dock9
|
APN |
14 |
121,595,611 (GRCm38) |
splice site |
probably null |
|
|
IGL02795:Dock9
|
APN |
14 |
121,639,978 (GRCm38) |
missense |
probably benign |
0.04 |
|
IGL03074:Dock9
|
APN |
14 |
121,607,270 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL03095:Dock9
|
APN |
14 |
121,639,528 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03294:Dock9
|
APN |
14 |
121,641,623 (GRCm38) |
splice site |
probably benign |
|
|
R0036:Dock9
|
UTSW |
14 |
121,622,853 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0050:Dock9
|
UTSW |
14 |
121,607,225 (GRCm38) |
missense |
probably benign |
0.43 |
|
R0050:Dock9
|
UTSW |
14 |
121,607,225 (GRCm38) |
missense |
probably benign |
0.43 |
|
R0164:Dock9
|
UTSW |
14 |
121,597,665 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0164:Dock9
|
UTSW |
14 |
121,597,665 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0270:Dock9
|
UTSW |
14 |
121,575,999 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0494:Dock9
|
UTSW |
14 |
121,662,584 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R0726:Dock9
|
UTSW |
14 |
121,651,768 (GRCm38) |
nonsense |
probably null |
|
|
R1029:Dock9
|
UTSW |
14 |
121,599,684 (GRCm38) |
splice site |
probably null |
|
|
R1214:Dock9
|
UTSW |
14 |
121,586,316 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1231:Dock9
|
UTSW |
14 |
121,575,950 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R1535:Dock9
|
UTSW |
14 |
121,546,064 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1629:Dock9
|
UTSW |
14 |
121,543,574 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R1637:Dock9
|
UTSW |
14 |
121,651,775 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R1733:Dock9
|
UTSW |
14 |
121,626,880 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1772:Dock9
|
UTSW |
14 |
121,609,798 (GRCm38) |
missense |
probably benign |
0.07 |
|
R1855:Dock9
|
UTSW |
14 |
121,640,159 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1888:Dock9
|
UTSW |
14 |
121,625,205 (GRCm38) |
missense |
probably benign |
0.18 |
|
R1888:Dock9
|
UTSW |
14 |
121,625,205 (GRCm38) |
missense |
probably benign |
0.18 |
|
R1901:Dock9
|
UTSW |
14 |
121,625,153 (GRCm38) |
splice site |
probably null |
|
|
R1920:Dock9
|
UTSW |
14 |
121,583,380 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1987:Dock9
|
UTSW |
14 |
121,591,830 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3035:Dock9
|
UTSW |
14 |
121,606,837 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R3851:Dock9
|
UTSW |
14 |
121,629,086 (GRCm38) |
splice site |
probably null |
|
|
R4020:Dock9
|
UTSW |
14 |
121,606,855 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4021:Dock9
|
UTSW |
14 |
121,626,912 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R4089:Dock9
|
UTSW |
14 |
121,583,471 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4258:Dock9
|
UTSW |
14 |
121,581,442 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4423:Dock9
|
UTSW |
14 |
121,562,053 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4561:Dock9
|
UTSW |
14 |
121,559,007 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4604:Dock9
|
UTSW |
14 |
121,668,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4646:Dock9
|
UTSW |
14 |
121,586,246 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4647:Dock9
|
UTSW |
14 |
121,586,246 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4776:Dock9
|
UTSW |
14 |
121,610,097 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R4809:Dock9
|
UTSW |
14 |
121,546,596 (GRCm38) |
missense |
probably benign |
0.37 |
|
R4865:Dock9
|
UTSW |
14 |
121,543,505 (GRCm38) |
makesense |
probably null |
|
|
R4951:Dock9
|
UTSW |
14 |
121,653,135 (GRCm38) |
missense |
probably benign |
0.35 |
|
R5151:Dock9
|
UTSW |
14 |
121,578,170 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5359:Dock9
|
UTSW |
14 |
121,653,060 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R5366:Dock9
|
UTSW |
14 |
121,578,203 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5502:Dock9
|
UTSW |
14 |
121,610,182 (GRCm38) |
splice site |
probably null |
|
|
R5579:Dock9
|
UTSW |
14 |
121,599,695 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5753:Dock9
|
UTSW |
14 |
121,634,625 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5836:Dock9
|
UTSW |
14 |
121,681,351 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5858:Dock9
|
UTSW |
14 |
121,628,792 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5890:Dock9
|
UTSW |
14 |
121,668,408 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6075:Dock9
|
UTSW |
14 |
121,545,973 (GRCm38) |
missense |
probably benign |
|
|
R6298:Dock9
|
UTSW |
14 |
121,634,594 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6306:Dock9
|
UTSW |
14 |
121,562,080 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6321:Dock9
|
UTSW |
14 |
121,546,021 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6330:Dock9
|
UTSW |
14 |
121,605,243 (GRCm38) |
start codon destroyed |
probably null |
0.00 |
|
R6719:Dock9
|
UTSW |
14 |
121,610,027 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6784:Dock9
|
UTSW |
14 |
121,543,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6826:Dock9
|
UTSW |
14 |
121,622,918 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6830:Dock9
|
UTSW |
14 |
121,622,918 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6838:Dock9
|
UTSW |
14 |
121,546,596 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R6868:Dock9
|
UTSW |
14 |
121,586,264 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6919:Dock9
|
UTSW |
14 |
121,643,152 (GRCm38) |
missense |
probably benign |
0.42 |
|
R6989:Dock9
|
UTSW |
14 |
121,627,379 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7539:Dock9
|
UTSW |
14 |
121,581,436 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7645:Dock9
|
UTSW |
14 |
121,597,663 (GRCm38) |
missense |
probably benign |
0.44 |
|
R7875:Dock9
|
UTSW |
14 |
121,625,984 (GRCm38) |
nonsense |
probably null |
|
|
R7900:Dock9
|
UTSW |
14 |
121,546,079 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R8040:Dock9
|
UTSW |
14 |
121,651,794 (GRCm38) |
missense |
probably benign |
0.06 |
|
R8420:Dock9
|
UTSW |
14 |
121,546,042 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8511:Dock9
|
UTSW |
14 |
121,681,435 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8511:Dock9
|
UTSW |
14 |
121,627,389 (GRCm38) |
missense |
probably benign |
0.40 |
|
R8514:Dock9
|
UTSW |
14 |
121,658,787 (GRCm38) |
missense |
probably benign |
0.25 |
|
R8691:Dock9
|
UTSW |
14 |
121,640,105 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R8804:Dock9
|
UTSW |
14 |
121,605,183 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8894:Dock9
|
UTSW |
14 |
121,622,961 (GRCm38) |
missense |
probably benign |
0.10 |
|
R8900:Dock9
|
UTSW |
14 |
121,580,528 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9069:Dock9
|
UTSW |
14 |
121,628,912 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9218:Dock9
|
UTSW |
14 |
121,668,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9233:Dock9
|
UTSW |
14 |
121,583,369 (GRCm38) |
missense |
probably benign |
0.09 |
|
R9236:Dock9
|
UTSW |
14 |
121,639,558 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9285:Dock9
|
UTSW |
14 |
121,595,600 (GRCm38) |
missense |
probably benign |
|
|
R9451:Dock9
|
UTSW |
14 |
121,550,189 (GRCm38) |
splice site |
probably benign |
|
|
R9461:Dock9
|
UTSW |
14 |
121,605,189 (GRCm38) |
missense |
probably benign |
0.05 |
|
R9517:Dock9
|
UTSW |
14 |
121,591,824 (GRCm38) |
missense |
probably benign |
0.07 |
|
R9542:Dock9
|
UTSW |
14 |
121,627,363 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9694:Dock9
|
UTSW |
14 |
121,581,379 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9701:Dock9
|
UTSW |
14 |
121,639,571 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9703:Dock9
|
UTSW |
14 |
121,544,577 (GRCm38) |
makesense |
probably null |
|
|
R9726:Dock9
|
UTSW |
14 |
121,597,737 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R9741:Dock9
|
UTSW |
14 |
121,640,104 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Dock9
|
UTSW |
14 |
121,555,275 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Dock9
|
UTSW |
14 |
121,651,782 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACTCATGACGGTACCCACTTTC -3'
(R):5'- CGCCTTTGTAAATGCATTAGGG -3'
Sequencing Primer
(F):5'- GACGGTACCCACTTTCTCCTGATG -3'
(R):5'- GCCTTTGTAAATGCATTAGGGAAAAC -3'
|
| Posted On |
2022-07-18 |
Incidental Mutation