Incidental Mutation 'R9484:Thada'
| ID |
716486 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Thada
|
| Ensembl Gene |
ENSMUSG00000024251 |
| Gene Name |
thyroid adenoma associated |
| Synonyms |
|
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9484 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
84497504-84773633 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 84736619 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Phenylalanine
at position 887
(L887F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041701
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047524]
|
| AlphaFold |
A8C756 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000047524
AA Change: L887F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000041701
Gene: ENSMUSG00000024251
AA Change: L887F
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
457 |
926 |
3e-6 |
SMART |
|
Pfam:DUF2428
|
938 |
1239 |
1.6e-93 |
PFAM |
|
SCOP:d1gw5a_
|
1343 |
1802 |
7e-6 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.8%
- 10x: 99.2%
- 20x: 97.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acads |
A |
T |
5: 115,250,845 (GRCm39) |
C151S |
probably damaging |
Het |
| Actr8 |
T |
C |
14: 29,708,301 (GRCm39) |
I193T |
probably benign |
Het |
| Btbd2 |
T |
C |
10: 80,480,103 (GRCm39) |
N419S |
probably benign |
Het |
| Cacna2d1 |
T |
A |
5: 16,561,831 (GRCm39) |
W821R |
probably damaging |
Het |
| Cadps2 |
T |
C |
6: 23,626,646 (GRCm39) |
Y214C |
probably benign |
Het |
| Calu |
T |
A |
6: 29,366,162 (GRCm39) |
L180Q |
probably damaging |
Het |
| Corin |
C |
T |
5: 72,497,280 (GRCm39) |
V615I |
probably damaging |
Het |
| Cyp8b1 |
A |
T |
9: 121,744,983 (GRCm39) |
D116E |
probably benign |
Het |
| D630036H23Rik |
C |
A |
12: 36,431,711 (GRCm39) |
A96S |
unknown |
Het |
| Ddx24 |
A |
T |
12: 103,377,555 (GRCm39) |
Y717N |
probably damaging |
Het |
| Dmap1 |
G |
T |
4: 117,533,308 (GRCm39) |
Q249K |
probably benign |
Het |
| Dnah10 |
T |
A |
5: 124,900,508 (GRCm39) |
W3922R |
probably damaging |
Het |
| Dnah14 |
T |
C |
1: 181,517,773 (GRCm39) |
F2036L |
probably benign |
Het |
| Dnah14 |
T |
C |
1: 181,625,311 (GRCm39) |
I4064T |
probably benign |
Het |
| Dock9 |
A |
C |
14: 121,818,844 (GRCm39) |
V1546G |
probably damaging |
Het |
| Eif1ad4 |
A |
T |
12: 87,862,249 (GRCm39) |
Q37L |
possibly damaging |
Het |
| Eif3a |
A |
T |
19: 60,755,006 (GRCm39) |
S1059T |
unknown |
Het |
| Ep300 |
A |
G |
15: 81,521,026 (GRCm39) |
E1262G |
unknown |
Het |
| Evl |
T |
A |
12: 108,652,716 (GRCm39) |
I387N |
probably damaging |
Het |
| Fat2 |
A |
C |
11: 55,200,752 (GRCm39) |
V774G |
probably damaging |
Het |
| Fez1 |
T |
A |
9: 36,755,093 (GRCm39) |
Y31N |
probably benign |
Het |
| Fkbp10 |
A |
G |
11: 100,313,960 (GRCm39) |
I435V |
probably damaging |
Het |
| Flnb |
A |
G |
14: 7,929,004 (GRCm38) |
D1911G |
probably benign |
Het |
| Fnbp1 |
T |
C |
2: 30,973,038 (GRCm39) |
Y154C |
probably benign |
Het |
| Fndc10 |
T |
C |
4: 155,779,496 (GRCm39) |
I180T |
possibly damaging |
Het |
| Frmd4a |
G |
A |
2: 4,609,026 (GRCm39) |
V965I |
possibly damaging |
Het |
| Gabrr2 |
A |
G |
4: 33,071,352 (GRCm39) |
H64R |
possibly damaging |
Het |
| Glis3 |
T |
C |
19: 28,508,403 (GRCm39) |
D527G |
probably damaging |
Het |
| H2-Ob |
T |
A |
17: 34,459,989 (GRCm39) |
F33L |
probably damaging |
Het |
| Hbb-bh1 |
C |
T |
7: 103,492,239 (GRCm39) |
E27K |
probably benign |
Het |
| Ifnb1 |
T |
A |
4: 88,440,915 (GRCm39) |
T33S |
probably benign |
Het |
| Igkv4-80 |
T |
A |
6: 68,993,766 (GRCm39) |
T42S |
probably damaging |
Het |
| Irs2 |
C |
T |
8: 11,057,334 (GRCm39) |
G366D |
probably damaging |
Het |
| Kcnk2 |
CAAA |
CAA |
1: 188,988,891 (GRCm39) |
|
probably null |
Het |
| Krtap5-3 |
T |
A |
7: 141,756,068 (GRCm39) |
C302S |
unknown |
Het |
| Lgi1 |
A |
G |
19: 38,294,757 (GRCm39) |
K510E |
probably benign |
Het |
| Lgi2 |
T |
A |
5: 52,695,936 (GRCm39) |
D341V |
probably benign |
Het |
| Lin7c |
T |
C |
2: 109,724,813 (GRCm39) |
I14T |
probably benign |
Het |
| Lrrc19 |
A |
T |
4: 94,531,573 (GRCm39) |
M13K |
probably benign |
Het |
| Lrrc69 |
T |
C |
4: 14,666,012 (GRCm39) |
I315M |
probably benign |
Het |
| Mtcl3 |
G |
A |
10: 29,072,969 (GRCm39) |
D754N |
probably damaging |
Het |
| Myo5c |
A |
T |
9: 75,204,770 (GRCm39) |
D1541V |
probably damaging |
Het |
| Mypn |
T |
G |
10: 63,003,019 (GRCm39) |
M373L |
probably benign |
Het |
| Nckipsd |
C |
A |
9: 108,689,837 (GRCm39) |
H333N |
probably damaging |
Het |
| Nrg2 |
A |
T |
18: 36,157,401 (GRCm39) |
L428Q |
probably null |
Het |
| Or13a20 |
T |
C |
7: 140,231,904 (GRCm39) |
L4S |
probably benign |
Het |
| Or2b28 |
C |
A |
13: 21,531,587 (GRCm39) |
T163K |
probably damaging |
Het |
| Or5an11 |
T |
C |
19: 12,245,735 (GRCm39) |
I47T |
possibly damaging |
Het |
| Otogl |
T |
A |
10: 107,657,894 (GRCm39) |
|
probably null |
Het |
| Otogl |
C |
T |
10: 107,737,156 (GRCm39) |
G86D |
probably damaging |
Het |
| Papln |
A |
T |
12: 83,838,618 (GRCm39) |
Q1249L |
probably benign |
Het |
| Plxna2 |
G |
T |
1: 194,327,202 (GRCm39) |
G379C |
probably damaging |
Het |
| Pofut2 |
T |
C |
10: 77,095,260 (GRCm39) |
I35T |
probably benign |
Het |
| Pros1 |
A |
G |
16: 62,744,887 (GRCm39) |
T501A |
possibly damaging |
Het |
| Rapgef1 |
T |
C |
2: 29,625,821 (GRCm39) |
S1042P |
possibly damaging |
Het |
| Rps6kb1 |
C |
T |
11: 86,408,443 (GRCm39) |
E185K |
probably damaging |
Het |
| Slc13a2 |
A |
T |
11: 78,294,233 (GRCm39) |
L216Q |
probably damaging |
Het |
| Slc22a14 |
T |
C |
9: 119,009,615 (GRCm39) |
Y160C |
probably damaging |
Het |
| Slc22a4 |
T |
A |
11: 53,879,773 (GRCm39) |
I429F |
possibly damaging |
Het |
| Slc26a3 |
A |
G |
12: 31,511,785 (GRCm39) |
K457E |
probably damaging |
Het |
| Slc47a2 |
T |
C |
11: 61,227,060 (GRCm39) |
I169M |
possibly damaging |
Het |
| Slco1a1 |
C |
T |
6: 141,854,672 (GRCm39) |
V660I |
probably benign |
Het |
| Smyd1 |
A |
G |
6: 71,202,450 (GRCm39) |
Y252H |
probably damaging |
Het |
| Spp2 |
A |
T |
1: 88,334,695 (GRCm39) |
|
probably benign |
Het |
| Stra8 |
T |
A |
6: 34,911,121 (GRCm39) |
W250R |
probably damaging |
Het |
| Syne1 |
A |
C |
10: 5,170,359 (GRCm39) |
L5183R |
probably damaging |
Het |
| Tdrd9 |
T |
C |
12: 112,012,684 (GRCm39) |
S1203P |
probably damaging |
Het |
| Th |
C |
A |
7: 142,453,620 (GRCm39) |
E27* |
probably null |
Het |
| Timm23 |
T |
C |
14: 31,902,586 (GRCm39) |
T186A |
probably benign |
Het |
| Tmem132b |
A |
T |
5: 125,860,420 (GRCm39) |
E555V |
probably damaging |
Het |
| Tnik |
A |
T |
3: 28,649,093 (GRCm39) |
Q457L |
unknown |
Het |
| Uba7 |
C |
A |
9: 107,861,037 (GRCm39) |
H942Q |
probably benign |
Het |
| Upf2 |
T |
C |
2: 5,966,078 (GRCm39) |
S233P |
unknown |
Het |
| Urm1 |
T |
A |
2: 29,732,760 (GRCm39) |
N72K |
probably damaging |
Het |
| Usp10 |
T |
C |
8: 120,675,504 (GRCm39) |
S508P |
possibly damaging |
Het |
| Usp37 |
G |
A |
1: 74,499,081 (GRCm39) |
P632S |
probably damaging |
Het |
| Wdr77 |
T |
A |
3: 105,872,404 (GRCm39) |
N209K |
probably benign |
Het |
| Zbtb24 |
C |
T |
10: 41,327,429 (GRCm39) |
T105M |
probably benign |
Het |
| Zfp341 |
T |
A |
2: 154,485,763 (GRCm39) |
I671N |
probably damaging |
Het |
| Zfp414 |
A |
G |
17: 33,848,984 (GRCm39) |
T73A |
probably benign |
Het |
| Zfp574 |
A |
T |
7: 24,781,404 (GRCm39) |
I809F |
possibly damaging |
Het |
| Zfp62 |
T |
C |
11: 49,108,108 (GRCm39) |
I733T |
probably damaging |
Het |
| Zfp719 |
A |
G |
7: 43,239,581 (GRCm39) |
I390V |
possibly damaging |
Het |
|
| Other mutations in Thada |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00672:Thada
|
APN |
17 |
84,751,646 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00902:Thada
|
APN |
17 |
84,755,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01634:Thada
|
APN |
17 |
84,700,786 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01689:Thada
|
APN |
17 |
84,754,116 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01693:Thada
|
APN |
17 |
84,754,072 (GRCm39) |
missense |
probably benign |
|
|
IGL01937:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01945:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02231:Thada
|
APN |
17 |
84,736,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Thada
|
APN |
17 |
84,751,456 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL03167:Thada
|
APN |
17 |
84,766,277 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03279:Thada
|
APN |
17 |
84,742,988 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03347:Thada
|
APN |
17 |
84,705,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
H8562:Thada
|
UTSW |
17 |
84,753,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03098:Thada
|
UTSW |
17 |
84,641,569 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0006:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0357:Thada
|
UTSW |
17 |
84,538,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0388:Thada
|
UTSW |
17 |
84,538,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0543:Thada
|
UTSW |
17 |
84,730,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:Thada
|
UTSW |
17 |
84,723,731 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0630:Thada
|
UTSW |
17 |
84,536,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0664:Thada
|
UTSW |
17 |
84,644,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0855:Thada
|
UTSW |
17 |
84,744,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0972:Thada
|
UTSW |
17 |
84,736,490 (GRCm39) |
splice site |
probably benign |
|
|
R1297:Thada
|
UTSW |
17 |
84,559,863 (GRCm39) |
splice site |
probably benign |
|
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1490:Thada
|
UTSW |
17 |
84,754,029 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1789:Thada
|
UTSW |
17 |
84,755,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Thada
|
UTSW |
17 |
84,755,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1802:Thada
|
UTSW |
17 |
84,771,835 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1831:Thada
|
UTSW |
17 |
84,538,542 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1834:Thada
|
UTSW |
17 |
84,533,432 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1881:Thada
|
UTSW |
17 |
84,744,130 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1925:Thada
|
UTSW |
17 |
84,751,927 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1969:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1971:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2149:Thada
|
UTSW |
17 |
84,749,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2191:Thada
|
UTSW |
17 |
84,753,949 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2571:Thada
|
UTSW |
17 |
84,762,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3405:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3406:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3916:Thada
|
UTSW |
17 |
84,749,210 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4044:Thada
|
UTSW |
17 |
84,749,135 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4461:Thada
|
UTSW |
17 |
84,733,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4662:Thada
|
UTSW |
17 |
84,743,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4786:Thada
|
UTSW |
17 |
84,766,283 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4803:Thada
|
UTSW |
17 |
84,580,245 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4835:Thada
|
UTSW |
17 |
84,748,532 (GRCm39) |
splice site |
probably null |
|
|
R4872:Thada
|
UTSW |
17 |
84,754,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4898:Thada
|
UTSW |
17 |
84,755,470 (GRCm39) |
splice site |
probably null |
|
|
R4903:Thada
|
UTSW |
17 |
84,559,828 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4929:Thada
|
UTSW |
17 |
84,751,654 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4959:Thada
|
UTSW |
17 |
84,751,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5071:Thada
|
UTSW |
17 |
84,693,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5092:Thada
|
UTSW |
17 |
84,751,896 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5398:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5480:Thada
|
UTSW |
17 |
84,739,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5552:Thada
|
UTSW |
17 |
84,736,558 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5575:Thada
|
UTSW |
17 |
84,723,827 (GRCm39) |
splice site |
probably null |
|
|
R5623:Thada
|
UTSW |
17 |
84,499,411 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5688:Thada
|
UTSW |
17 |
84,759,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5704:Thada
|
UTSW |
17 |
84,538,329 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6008:Thada
|
UTSW |
17 |
84,744,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6013:Thada
|
UTSW |
17 |
84,580,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6072:Thada
|
UTSW |
17 |
84,499,434 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6156:Thada
|
UTSW |
17 |
84,700,795 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6243:Thada
|
UTSW |
17 |
84,744,030 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6449:Thada
|
UTSW |
17 |
84,736,601 (GRCm39) |
missense |
probably benign |
|
|
R6453:Thada
|
UTSW |
17 |
84,723,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Thada
|
UTSW |
17 |
84,751,339 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6732:Thada
|
UTSW |
17 |
84,761,842 (GRCm39) |
splice site |
probably null |
|
|
R6907:Thada
|
UTSW |
17 |
84,700,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Thada
|
UTSW |
17 |
84,538,214 (GRCm39) |
splice site |
probably null |
|
|
R7167:Thada
|
UTSW |
17 |
84,538,391 (GRCm39) |
missense |
probably benign |
|
|
R7221:Thada
|
UTSW |
17 |
84,771,794 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7470:Thada
|
UTSW |
17 |
84,533,469 (GRCm39) |
missense |
probably benign |
|
|
R7753:Thada
|
UTSW |
17 |
84,559,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7809:Thada
|
UTSW |
17 |
84,759,265 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7882:Thada
|
UTSW |
17 |
84,736,624 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7971:Thada
|
UTSW |
17 |
84,580,197 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8004:Thada
|
UTSW |
17 |
84,499,633 (GRCm39) |
missense |
probably benign |
|
|
R8153:Thada
|
UTSW |
17 |
84,700,855 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8254:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8426:Thada
|
UTSW |
17 |
84,530,131 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8438:Thada
|
UTSW |
17 |
84,743,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8670:Thada
|
UTSW |
17 |
84,739,774 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8679:Thada
|
UTSW |
17 |
84,536,637 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8952:Thada
|
UTSW |
17 |
84,736,524 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8983:Thada
|
UTSW |
17 |
84,538,515 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9009:Thada
|
UTSW |
17 |
84,759,203 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9050:Thada
|
UTSW |
17 |
84,736,629 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9091:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9225:Thada
|
UTSW |
17 |
84,749,172 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9251:Thada
|
UTSW |
17 |
84,538,564 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9270:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9299:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9337:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9360:Thada
|
UTSW |
17 |
84,499,410 (GRCm39) |
missense |
probably benign |
|
|
R9416:Thada
|
UTSW |
17 |
84,766,292 (GRCm39) |
nonsense |
probably null |
|
|
R9584:Thada
|
UTSW |
17 |
84,733,605 (GRCm39) |
missense |
probably benign |
|
|
R9631:Thada
|
UTSW |
17 |
84,538,584 (GRCm39) |
missense |
probably benign |
0.17 |
|
Z1176:Thada
|
UTSW |
17 |
84,751,858 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTTTCCCAAGACACACTCCAGTG -3'
(R):5'- TTGGTAACGGGCTGATACCC -3'
Sequencing Primer
(F):5'- CTCCAGTGAGAAGCTAAAGGTAG -3'
(R):5'- TGACCTGAGTTGGAATCACC -3'
|
| Posted On |
2022-07-18 |
Incidental Mutation