Incidental Mutation 'R9487:Rasgrf2'
| ID |
716694 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rasgrf2
|
| Ensembl Gene |
ENSMUSG00000021708 |
| Gene Name |
RAS protein-specific guanine nucleotide-releasing factor 2 |
| Synonyms |
Grf2, 6330417G04Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.222)
|
| Stock # |
R9487 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
92028519-92268164 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 92267759 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 82
(T82A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000096930
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099326]
[ENSMUST00000146492]
[ENSMUST00000216219]
|
| AlphaFold |
P70392 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000099326
AA Change: T82A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000096930
Gene: ENSMUSG00000021708
AA Change: T82A
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
23 |
135 |
1.29e-16 |
SMART |
|
IQ
|
204 |
226 |
1.3e0 |
SMART |
|
RhoGEF
|
247 |
428 |
2.2e-51 |
SMART |
|
RasGEFN
|
633 |
775 |
9.35e-15 |
SMART |
|
RasGEFN
|
786 |
923 |
6.04e-9 |
SMART |
|
RasGEF
|
949 |
1186 |
2.97e-112 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000146492
AA Change: T82A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000116203
Gene: ENSMUSG00000021708
AA Change: T82A
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
23 |
135 |
1.29e-16 |
SMART |
|
IQ
|
204 |
226 |
1.3e0 |
SMART |
|
Pfam:RhoGEF
|
247 |
387 |
1.2e-24 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000216219
AA Change: T82A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a targeted null mutation exhibit decreased Il2 and TNF-alpha production in stimulated T cells. Mice homozygous for mutations in both Rasgrf1 and Rasgrf2 exhibit no additional abnormalities than those observed in the Rasgrf1 mutant mice. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700019A02Rik |
C |
T |
1: 53,221,665 (GRCm39) |
D55N |
possibly damaging |
Het |
| Abcc2 |
G |
A |
19: 43,806,471 (GRCm39) |
G762S |
probably damaging |
Het |
| Acta2 |
C |
A |
19: 34,225,865 (GRCm39) |
A110S |
probably damaging |
Het |
| Adam26a |
T |
C |
8: 44,022,456 (GRCm39) |
T345A |
possibly damaging |
Het |
| Anapc11 |
T |
C |
11: 120,496,250 (GRCm39) |
*85R |
probably null |
Het |
| Ang2 |
A |
C |
14: 51,433,071 (GRCm39) |
C104G |
probably damaging |
Het |
| Ankzf1 |
G |
A |
1: 75,174,596 (GRCm39) |
V529I |
probably benign |
Het |
| Aox4 |
G |
T |
1: 58,288,097 (GRCm39) |
V737F |
probably benign |
Het |
| Aqr |
T |
C |
2: 113,934,528 (GRCm39) |
N1371S |
probably benign |
Het |
| Bach1 |
T |
A |
16: 87,526,733 (GRCm39) |
S732T |
probably benign |
Het |
| Bcr |
T |
A |
10: 74,967,431 (GRCm39) |
I555N |
probably damaging |
Het |
| Bicra |
T |
C |
7: 15,705,717 (GRCm39) |
T1575A |
probably damaging |
Het |
| Bop1 |
A |
G |
15: 76,338,076 (GRCm39) |
L598P |
probably damaging |
Het |
| Cacna1d |
A |
T |
14: 29,845,419 (GRCm39) |
F605L |
possibly damaging |
Het |
| Capn15 |
C |
T |
17: 26,184,353 (GRCm39) |
V109I |
possibly damaging |
Het |
| Cdkn1b |
T |
C |
6: 134,897,815 (GRCm39) |
|
probably benign |
Het |
| Dnah2 |
T |
C |
11: 69,406,617 (GRCm39) |
T542A |
possibly damaging |
Het |
| Dsc2 |
A |
T |
18: 20,180,276 (GRCm39) |
I159N |
probably damaging |
Het |
| Ecel1 |
A |
T |
1: 87,075,716 (GRCm39) |
V774E |
probably damaging |
Het |
| Eif5b |
T |
G |
1: 38,084,560 (GRCm39) |
C849W |
probably damaging |
Het |
| Eif5b |
T |
A |
1: 38,058,451 (GRCm39) |
L251* |
probably null |
Het |
| Ext2 |
T |
C |
2: 93,592,956 (GRCm39) |
D416G |
probably damaging |
Het |
| Fancm |
G |
A |
12: 65,153,388 (GRCm39) |
W1281* |
probably null |
Het |
| Flvcr1 |
A |
T |
1: 190,743,829 (GRCm39) |
I409K |
possibly damaging |
Het |
| Foxk1 |
T |
C |
5: 142,437,389 (GRCm39) |
|
probably null |
Het |
| Frem2 |
T |
A |
3: 53,560,905 (GRCm39) |
I1201F |
possibly damaging |
Het |
| Gabra5 |
A |
G |
7: 57,157,873 (GRCm39) |
|
probably benign |
Het |
| Gmpr2 |
G |
A |
14: 55,915,778 (GRCm39) |
V319I |
probably damaging |
Het |
| Gna12 |
A |
T |
5: 140,746,338 (GRCm39) |
L369Q |
probably damaging |
Het |
| Gpr160 |
A |
G |
3: 30,950,914 (GRCm39) |
R329G |
probably benign |
Het |
| H2-M10.3 |
T |
C |
17: 36,677,423 (GRCm39) |
H285R |
probably benign |
Het |
| H2-M2 |
A |
T |
17: 37,793,424 (GRCm39) |
V194E |
probably benign |
Het |
| Hephl1 |
G |
A |
9: 14,995,830 (GRCm39) |
R431W |
possibly damaging |
Het |
| Hr |
A |
G |
14: 70,793,877 (GRCm39) |
T46A |
probably benign |
Het |
| Hr |
A |
G |
14: 70,794,205 (GRCm39) |
H126R |
possibly damaging |
Het |
| Hsf1 |
T |
G |
15: 76,382,398 (GRCm39) |
D256E |
probably benign |
Het |
| Ifi208 |
C |
T |
1: 173,510,961 (GRCm39) |
T372I |
probably damaging |
Het |
| Ifi47 |
T |
G |
11: 48,986,620 (GRCm39) |
F129C |
probably damaging |
Het |
| Il1rl2 |
CTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATT |
CTTTATTTTATTTTATTTTATTTTATTTTATTTTATT |
1: 40,366,470 (GRCm39) |
|
probably benign |
Het |
| Irag2 |
A |
G |
6: 145,120,257 (GRCm39) |
I491V |
probably benign |
Het |
| Itga11 |
A |
T |
9: 62,670,171 (GRCm39) |
N765I |
probably benign |
Het |
| Klhl22 |
T |
A |
16: 17,589,663 (GRCm39) |
I108K |
probably benign |
Het |
| Lancl1 |
T |
G |
1: 67,073,381 (GRCm39) |
H34P |
probably benign |
Het |
| Lcor |
C |
A |
19: 41,573,685 (GRCm39) |
N813K |
probably damaging |
Het |
| Mbd3l1 |
G |
A |
9: 18,396,274 (GRCm39) |
G133D |
probably benign |
Het |
| Med12l |
T |
C |
3: 59,155,353 (GRCm39) |
F1178L |
probably benign |
Het |
| Mrm1 |
A |
T |
11: 84,705,531 (GRCm39) |
N289K |
probably damaging |
Het |
| Myf6 |
A |
G |
10: 107,330,073 (GRCm39) |
Y165H |
probably benign |
Het |
| Myo1g |
C |
A |
11: 6,456,913 (GRCm39) |
C971F |
probably benign |
Het |
| Myo3a |
T |
C |
2: 22,245,862 (GRCm39) |
M3T |
probably benign |
Het |
| Nsrp1 |
G |
A |
11: 76,937,114 (GRCm39) |
R361* |
probably null |
Het |
| Or10d4 |
A |
C |
9: 39,580,611 (GRCm39) |
Q86P |
possibly damaging |
Het |
| Or10h1b |
C |
A |
17: 33,395,548 (GRCm39) |
H57Q |
possibly damaging |
Het |
| Or4a69 |
T |
C |
2: 89,312,756 (GRCm39) |
H241R |
probably damaging |
Het |
| Or4a77 |
T |
C |
2: 89,487,731 (GRCm39) |
D18G |
probably damaging |
Het |
| Or5p6 |
A |
T |
7: 107,631,163 (GRCm39) |
I129N |
possibly damaging |
Het |
| Or8b41 |
G |
A |
9: 38,054,866 (GRCm39) |
C140Y |
probably benign |
Het |
| Or8k53 |
T |
A |
2: 86,177,846 (GRCm39) |
D88V |
probably benign |
Het |
| Oscar |
T |
G |
7: 3,614,663 (GRCm39) |
Y103S |
probably damaging |
Het |
| Pdpr |
A |
G |
8: 111,852,925 (GRCm39) |
N610S |
probably benign |
Het |
| Ppp4r3b |
T |
C |
11: 29,124,697 (GRCm39) |
I56T |
probably damaging |
Het |
| Pxdn |
T |
A |
12: 30,044,552 (GRCm39) |
V510D |
possibly damaging |
Het |
| Rab11fip5 |
T |
C |
6: 85,324,913 (GRCm39) |
S465G |
possibly damaging |
Het |
| Scmh1 |
G |
A |
4: 120,320,284 (GRCm39) |
W30* |
probably null |
Het |
| Sema4g |
T |
C |
19: 44,981,071 (GRCm39) |
Y40H |
probably benign |
Het |
| Serpinf2 |
A |
T |
11: 75,323,494 (GRCm39) |
M404K |
probably damaging |
Het |
| Sgk3 |
T |
C |
1: 9,950,616 (GRCm39) |
|
probably null |
Het |
| Slc16a5 |
A |
T |
11: 115,360,738 (GRCm39) |
Y307F |
possibly damaging |
Het |
| Slc39a5 |
G |
A |
10: 128,233,628 (GRCm39) |
L290F |
probably damaging |
Het |
| Snx32 |
A |
C |
19: 5,547,736 (GRCm39) |
D191E |
probably damaging |
Het |
| Sp4 |
T |
C |
12: 118,262,859 (GRCm39) |
I396V |
probably benign |
Het |
| Srrd |
A |
G |
5: 112,490,765 (GRCm39) |
V42A |
unknown |
Het |
| Stim1 |
A |
G |
7: 102,080,257 (GRCm39) |
H547R |
unknown |
Het |
| Svep1 |
G |
A |
4: 58,070,517 (GRCm39) |
A2423V |
probably benign |
Het |
| Tep1 |
A |
G |
14: 51,066,687 (GRCm39) |
S2304P |
possibly damaging |
Het |
| Tkt |
C |
G |
14: 30,281,795 (GRCm39) |
S104R |
probably benign |
Het |
| Tkt |
T |
C |
14: 30,281,796 (GRCm39) |
S105P |
probably damaging |
Het |
| Tln1 |
A |
T |
4: 43,542,893 (GRCm39) |
N1365K |
probably damaging |
Het |
| Topaz1 |
G |
T |
9: 122,604,707 (GRCm39) |
A1104S |
probably benign |
Het |
| Trmt2a |
A |
G |
16: 18,068,814 (GRCm39) |
H270R |
probably damaging |
Het |
| Ttll10 |
G |
T |
4: 156,127,616 (GRCm39) |
T389K |
probably benign |
Het |
| Tubal3 |
A |
G |
13: 3,980,674 (GRCm39) |
I129V |
probably benign |
Het |
| Ucp3 |
A |
G |
7: 100,131,123 (GRCm39) |
E192G |
probably damaging |
Het |
| Usp47 |
A |
G |
7: 111,677,063 (GRCm39) |
D448G |
probably damaging |
Het |
| Vmn2r98 |
T |
A |
17: 19,301,496 (GRCm39) |
L833M |
possibly damaging |
Het |
| Vps13d |
A |
G |
4: 144,807,869 (GRCm39) |
|
probably null |
Het |
| Wdr7 |
A |
G |
18: 63,910,939 (GRCm39) |
D777G |
possibly damaging |
Het |
| Zcchc8 |
A |
G |
5: 123,847,300 (GRCm39) |
I213T |
probably damaging |
Het |
| Zfp281 |
T |
C |
1: 136,555,143 (GRCm39) |
I707T |
probably damaging |
Het |
| Zfp335 |
T |
C |
2: 164,735,395 (GRCm39) |
H1158R |
probably damaging |
Het |
| Zfp692 |
C |
T |
11: 58,199,765 (GRCm39) |
T118M |
probably damaging |
Het |
| Zfr2 |
T |
A |
10: 81,075,969 (GRCm39) |
L192Q |
probably benign |
Het |
|
| Other mutations in Rasgrf2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01308:Rasgrf2
|
APN |
13 |
92,159,425 (GRCm39) |
splice site |
probably benign |
|
|
IGL01358:Rasgrf2
|
APN |
13 |
92,130,749 (GRCm39) |
missense |
probably benign |
0.23 |
|
IGL01666:Rasgrf2
|
APN |
13 |
92,174,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01930:Rasgrf2
|
APN |
13 |
92,130,857 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02230:Rasgrf2
|
APN |
13 |
92,136,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02630:Rasgrf2
|
APN |
13 |
92,267,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02690:Rasgrf2
|
APN |
13 |
92,167,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Rasgrf2
|
APN |
13 |
92,131,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03067:Rasgrf2
|
APN |
13 |
92,159,413 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03342:Rasgrf2
|
APN |
13 |
92,136,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03405:Rasgrf2
|
APN |
13 |
92,044,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0620:Rasgrf2
|
UTSW |
13 |
92,067,936 (GRCm39) |
splice site |
probably benign |
|
|
R0632:Rasgrf2
|
UTSW |
13 |
92,120,393 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0894:Rasgrf2
|
UTSW |
13 |
92,130,890 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1354:Rasgrf2
|
UTSW |
13 |
92,165,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1400:Rasgrf2
|
UTSW |
13 |
92,035,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1437:Rasgrf2
|
UTSW |
13 |
92,167,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1443:Rasgrf2
|
UTSW |
13 |
92,131,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1522:Rasgrf2
|
UTSW |
13 |
92,044,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1553:Rasgrf2
|
UTSW |
13 |
92,038,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1613:Rasgrf2
|
UTSW |
13 |
92,050,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1883:Rasgrf2
|
UTSW |
13 |
92,117,149 (GRCm39) |
missense |
probably benign |
|
|
R1934:Rasgrf2
|
UTSW |
13 |
92,131,825 (GRCm39) |
splice site |
probably null |
|
|
R1990:Rasgrf2
|
UTSW |
13 |
92,172,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2037:Rasgrf2
|
UTSW |
13 |
92,050,748 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2043:Rasgrf2
|
UTSW |
13 |
92,167,351 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2135:Rasgrf2
|
UTSW |
13 |
92,120,374 (GRCm39) |
missense |
probably benign |
|
|
R2193:Rasgrf2
|
UTSW |
13 |
92,160,221 (GRCm39) |
splice site |
probably null |
|
|
R2406:Rasgrf2
|
UTSW |
13 |
92,120,359 (GRCm39) |
missense |
probably benign |
|
|
R3055:Rasgrf2
|
UTSW |
13 |
92,165,583 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3916:Rasgrf2
|
UTSW |
13 |
92,167,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3954:Rasgrf2
|
UTSW |
13 |
92,130,974 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3955:Rasgrf2
|
UTSW |
13 |
92,130,974 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3956:Rasgrf2
|
UTSW |
13 |
92,130,974 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4133:Rasgrf2
|
UTSW |
13 |
92,130,773 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R4177:Rasgrf2
|
UTSW |
13 |
92,038,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4178:Rasgrf2
|
UTSW |
13 |
92,038,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4357:Rasgrf2
|
UTSW |
13 |
92,038,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4358:Rasgrf2
|
UTSW |
13 |
92,038,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4359:Rasgrf2
|
UTSW |
13 |
92,038,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4439:Rasgrf2
|
UTSW |
13 |
92,131,797 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4440:Rasgrf2
|
UTSW |
13 |
92,131,797 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4441:Rasgrf2
|
UTSW |
13 |
92,131,797 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4564:Rasgrf2
|
UTSW |
13 |
92,033,773 (GRCm39) |
nonsense |
probably null |
|
|
R4576:Rasgrf2
|
UTSW |
13 |
92,044,529 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R4590:Rasgrf2
|
UTSW |
13 |
92,174,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4718:Rasgrf2
|
UTSW |
13 |
92,138,716 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4778:Rasgrf2
|
UTSW |
13 |
92,131,780 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4790:Rasgrf2
|
UTSW |
13 |
92,136,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4808:Rasgrf2
|
UTSW |
13 |
92,160,190 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5151:Rasgrf2
|
UTSW |
13 |
92,044,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5286:Rasgrf2
|
UTSW |
13 |
92,267,941 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5902:Rasgrf2
|
UTSW |
13 |
92,068,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6180:Rasgrf2
|
UTSW |
13 |
92,165,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6264:Rasgrf2
|
UTSW |
13 |
92,167,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6369:Rasgrf2
|
UTSW |
13 |
92,267,954 (GRCm39) |
missense |
probably benign |
|
|
R6428:Rasgrf2
|
UTSW |
13 |
92,136,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6595:Rasgrf2
|
UTSW |
13 |
92,167,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6619:Rasgrf2
|
UTSW |
13 |
92,165,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6988:Rasgrf2
|
UTSW |
13 |
92,033,754 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7026:Rasgrf2
|
UTSW |
13 |
92,131,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7038:Rasgrf2
|
UTSW |
13 |
92,130,952 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7045:Rasgrf2
|
UTSW |
13 |
92,159,100 (GRCm39) |
intron |
probably benign |
|
|
R7056:Rasgrf2
|
UTSW |
13 |
92,167,203 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7058:Rasgrf2
|
UTSW |
13 |
92,034,521 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7256:Rasgrf2
|
UTSW |
13 |
92,032,637 (GRCm39) |
nonsense |
probably null |
|
|
R7392:Rasgrf2
|
UTSW |
13 |
92,041,856 (GRCm39) |
missense |
|
|
|
R7469:Rasgrf2
|
UTSW |
13 |
92,165,530 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7618:Rasgrf2
|
UTSW |
13 |
92,136,085 (GRCm39) |
missense |
|
|
|
R7641:Rasgrf2
|
UTSW |
13 |
92,267,914 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7674:Rasgrf2
|
UTSW |
13 |
92,267,914 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7784:Rasgrf2
|
UTSW |
13 |
92,044,201 (GRCm39) |
missense |
|
|
|
R7962:Rasgrf2
|
UTSW |
13 |
92,167,300 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8056:Rasgrf2
|
UTSW |
13 |
92,167,321 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8218:Rasgrf2
|
UTSW |
13 |
92,130,796 (GRCm39) |
missense |
|
|
|
R8796:Rasgrf2
|
UTSW |
13 |
92,038,685 (GRCm39) |
missense |
|
|
|
R8913:Rasgrf2
|
UTSW |
13 |
92,159,034 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8971:Rasgrf2
|
UTSW |
13 |
92,158,225 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9020:Rasgrf2
|
UTSW |
13 |
92,165,146 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9562:Rasgrf2
|
UTSW |
13 |
92,034,469 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9712:Rasgrf2
|
UTSW |
13 |
92,136,092 (GRCm39) |
missense |
|
|
|
R9766:Rasgrf2
|
UTSW |
13 |
92,160,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9800:Rasgrf2
|
UTSW |
13 |
92,267,860 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0013:Rasgrf2
|
UTSW |
13 |
92,167,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Rasgrf2
|
UTSW |
13 |
92,050,654 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Rasgrf2
|
UTSW |
13 |
92,159,081 (GRCm39) |
missense |
unknown |
|
|
Z1177:Rasgrf2
|
UTSW |
13 |
92,131,632 (GRCm39) |
missense |
|
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTTGCTACAGGGTCTCCAAG -3'
(R):5'- CAATACTTCGGGTGGAGTGAC -3'
Sequencing Primer
(F):5'- TACAGGGTCTCCAAGCACTTG -3'
(R):5'- AGGGCAATCTGCGATGACC -3'
|
| Posted On |
2022-07-18 |
Incidental Mutation