Incidental Mutation 'R9492:Iqgap3'
| ID |
716973 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap3
|
| Ensembl Gene |
ENSMUSG00000028068 |
| Gene Name |
IQ motif containing GTPase activating protein 3 |
| Synonyms |
|
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.342)
|
| Stock # |
R9492 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
87989309-88028355 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 88016176 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 986
(F986L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071715
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071812]
[ENSMUST00000194440]
[ENSMUST00000195465]
|
| AlphaFold |
F8VQ29 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000071812
AA Change: F986L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000071715
Gene: ENSMUSG00000028068
AA Change: F986L
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
1.72e-14 |
SMART |
|
internal_repeat_2
|
197 |
249 |
1.75e-5 |
PROSPERO |
|
internal_repeat_1
|
209 |
418 |
1.31e-14 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
651 |
1.31e-14 |
PROSPERO |
|
internal_repeat_2
|
600 |
652 |
1.75e-5 |
PROSPERO |
|
IQ
|
730 |
752 |
1.18e1 |
SMART |
|
IQ
|
760 |
782 |
3.76e-6 |
SMART |
|
IQ
|
790 |
812 |
3.08e-2 |
SMART |
|
IQ
|
820 |
842 |
1.72e0 |
SMART |
|
RasGAP
|
977 |
1330 |
1.74e-57 |
SMART |
|
Blast:RasGAP
|
1338 |
1422 |
1e-9 |
BLAST |
|
Pfam:RasGAP_C
|
1434 |
1555 |
2e-36 |
PFAM |
|
low complexity region
|
1591 |
1602 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1630 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000194440
AA Change: F88L
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000142035
Gene: ENSMUSG00000028068
AA Change: F88L
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:RasGAP
|
1 |
67 |
3e-30 |
BLAST |
|
RasGAP
|
79 |
432 |
1e-59 |
SMART |
|
Blast:RasGAP
|
440 |
524 |
5e-10 |
BLAST |
|
Pfam:RasGAP_C
|
535 |
660 |
5.7e-30 |
PFAM |
|
low complexity region
|
693 |
704 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
732 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195465
|
| SMART Domains |
Protein: ENSMUSP00000142013
Gene: ENSMUSG00000028068
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
8.5e-17 |
SMART |
|
internal_repeat_1
|
209 |
379 |
1.33e-7 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
612 |
1.33e-7 |
PROSPERO |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 68 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3110009E18Rik |
A |
C |
1: 120,078,472 (GRCm39) |
K43T |
probably damaging |
Het |
| Abca12 |
A |
G |
1: 71,297,380 (GRCm39) |
V2370A |
possibly damaging |
Het |
| Abca13 |
T |
A |
11: 9,243,667 (GRCm39) |
C1843* |
probably null |
Het |
| Abr |
C |
T |
11: 76,399,751 (GRCm39) |
S82N |
probably benign |
Het |
| Acot2 |
T |
C |
12: 84,039,384 (GRCm39) |
S298P |
probably benign |
Het |
| Acrbp |
A |
G |
6: 125,038,062 (GRCm39) |
D421G |
probably benign |
Het |
| Adam25 |
A |
T |
8: 41,206,736 (GRCm39) |
M1L |
probably benign |
Het |
| Ano8 |
A |
G |
8: 71,934,784 (GRCm39) |
V441A |
possibly damaging |
Het |
| Aoc1l1 |
T |
C |
6: 48,955,540 (GRCm39) |
S717P |
probably benign |
Het |
| Atg2b |
T |
C |
12: 105,624,549 (GRCm39) |
H650R |
probably benign |
Het |
| Atp11a |
C |
T |
8: 12,894,490 (GRCm39) |
T695I |
probably damaging |
Het |
| AU018091 |
A |
G |
7: 3,214,023 (GRCm39) |
S74P |
probably benign |
Het |
| Cadps2 |
A |
G |
6: 23,427,238 (GRCm39) |
Y597H |
probably benign |
Het |
| Ccdc15 |
C |
T |
9: 37,215,665 (GRCm39) |
E619K |
probably damaging |
Het |
| Ceacam11 |
G |
T |
7: 17,709,468 (GRCm39) |
C222F |
probably benign |
Het |
| Cmya5 |
T |
C |
13: 93,177,822 (GRCm39) |
*3677W |
probably null |
Het |
| Col11a1 |
G |
C |
3: 114,005,752 (GRCm39) |
C1628S |
probably benign |
Het |
| Dhx8 |
T |
C |
11: 101,654,808 (GRCm39) |
I1032T |
possibly damaging |
Het |
| Dpp10 |
T |
C |
1: 123,281,159 (GRCm39) |
D630G |
probably damaging |
Het |
| Eci3 |
C |
T |
13: 35,143,976 (GRCm39) |
G50R |
probably benign |
Het |
| Eif2a |
A |
G |
3: 58,448,475 (GRCm39) |
T103A |
probably benign |
Het |
| Frem1 |
T |
C |
4: 82,920,057 (GRCm39) |
E432G |
probably damaging |
Het |
| Gdnf |
C |
T |
15: 7,840,423 (GRCm39) |
|
probably benign |
Het |
| Hace1 |
T |
A |
10: 45,547,230 (GRCm39) |
M471K |
probably benign |
Het |
| Hydin |
A |
G |
8: 111,326,877 (GRCm39) |
T4739A |
possibly damaging |
Het |
| Ilf2 |
A |
G |
3: 90,394,570 (GRCm39) |
I320V |
probably benign |
Het |
| Klhl21 |
T |
C |
4: 152,093,419 (GRCm39) |
L7S |
probably benign |
Het |
| Lrrc61 |
G |
T |
6: 48,545,761 (GRCm39) |
E195* |
probably null |
Het |
| Maz |
G |
T |
7: 126,622,292 (GRCm39) |
A443E |
possibly damaging |
Het |
| Mcm5 |
C |
T |
8: 75,844,168 (GRCm39) |
S313F |
probably benign |
Het |
| Mtor |
T |
A |
4: 148,568,801 (GRCm39) |
L1107Q |
probably damaging |
Het |
| Nectin3 |
T |
C |
16: 46,215,511 (GRCm39) |
H494R |
probably benign |
Het |
| Nlgn1 |
G |
T |
3: 25,488,480 (GRCm39) |
Y618* |
probably null |
Het |
| Nup98 |
C |
T |
7: 101,778,252 (GRCm39) |
E1372K |
probably benign |
Het |
| Or12e9 |
A |
G |
2: 87,201,960 (GRCm39) |
N28S |
probably benign |
Het |
| Or5af1 |
T |
C |
11: 58,722,610 (GRCm39) |
V210A |
probably benign |
Het |
| Otud6b |
A |
G |
4: 14,818,349 (GRCm39) |
I184T |
probably damaging |
Het |
| Pcsk6 |
A |
G |
7: 65,697,346 (GRCm39) |
N891S |
probably benign |
Het |
| Pde4a |
T |
A |
9: 21,106,096 (GRCm39) |
L237Q |
probably damaging |
Het |
| Peg10 |
CCACATCAGGATCCACATCAGGATGCACATCAGCATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAG |
CCACATCAGGATCCACATCAGGATGCACATCAG |
6: 4,756,398 (GRCm39) |
|
probably benign |
Het |
| Perm1 |
TGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCT |
TGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCT |
4: 156,302,525 (GRCm39) |
|
probably benign |
Het |
| Pou3f1 |
A |
G |
4: 124,552,179 (GRCm39) |
H227R |
possibly damaging |
Het |
| Prss53 |
G |
A |
7: 127,488,802 (GRCm39) |
R31C |
probably damaging |
Het |
| Psmb8 |
T |
A |
17: 34,417,435 (GRCm39) |
D21E |
probably benign |
Het |
| Ptprq |
A |
G |
10: 107,478,813 (GRCm39) |
Y1277H |
probably damaging |
Het |
| Rexo2 |
T |
C |
9: 48,380,176 (GRCm39) |
T219A |
probably benign |
Het |
| Rfc3 |
A |
G |
5: 151,566,411 (GRCm39) |
F346S |
probably damaging |
Het |
| Rhoq |
A |
T |
17: 87,304,373 (GRCm39) |
Q168L |
|
Het |
| Sgk1 |
A |
G |
10: 21,874,096 (GRCm39) |
N452S |
probably damaging |
Het |
| Slc35f3 |
A |
G |
8: 127,048,026 (GRCm39) |
K122R |
probably damaging |
Het |
| Slc4a2 |
T |
A |
5: 24,644,761 (GRCm39) |
M1021K |
probably benign |
Het |
| Sorcs2 |
A |
G |
5: 36,186,484 (GRCm39) |
V886A |
probably benign |
Het |
| Spata20 |
T |
A |
11: 94,374,444 (GRCm39) |
M308L |
probably damaging |
Het |
| Spen |
A |
T |
4: 141,199,098 (GRCm39) |
H3176Q |
probably benign |
Het |
| Stat5b |
T |
A |
11: 100,692,361 (GRCm39) |
H141L |
probably benign |
Het |
| Syne2 |
T |
A |
12: 75,995,839 (GRCm39) |
H2126Q |
possibly damaging |
Het |
| Traj46 |
A |
G |
14: 54,409,851 (GRCm39) |
T20A |
|
Het |
| Trim30a |
G |
T |
7: 104,078,330 (GRCm39) |
Q249K |
probably damaging |
Het |
| Trmt13 |
A |
G |
3: 116,388,281 (GRCm39) |
Y52H |
probably benign |
Het |
| Trpv3 |
A |
G |
11: 73,187,267 (GRCm39) |
I700V |
probably damaging |
Het |
| Tyr |
G |
A |
7: 87,121,704 (GRCm39) |
H363Y |
probably damaging |
Het |
| Tyr |
C |
G |
7: 87,121,705 (GRCm39) |
M362I |
possibly damaging |
Het |
| Ubb |
G |
A |
11: 62,442,984 (GRCm39) |
V5M |
probably damaging |
Het |
| Unc5a |
T |
C |
13: 55,150,288 (GRCm39) |
L519P |
probably damaging |
Het |
| Uso1 |
A |
G |
5: 92,315,191 (GRCm39) |
D185G |
possibly damaging |
Het |
| Vmn1r228 |
C |
T |
17: 20,996,862 (GRCm39) |
E219K |
probably damaging |
Het |
| Wdr49 |
A |
G |
3: 75,240,669 (GRCm39) |
V400A |
probably damaging |
Het |
| Zfp292 |
A |
G |
4: 34,810,794 (GRCm39) |
M755T |
probably benign |
Het |
|
| Other mutations in Iqgap3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Iqgap3
|
APN |
3 |
88,014,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01062:Iqgap3
|
APN |
3 |
88,017,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01517:Iqgap3
|
APN |
3 |
88,016,703 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01530:Iqgap3
|
APN |
3 |
88,019,610 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01658:Iqgap3
|
APN |
3 |
88,023,278 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02027:Iqgap3
|
APN |
3 |
87,994,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02352:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02359:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02522:Iqgap3
|
APN |
3 |
88,015,705 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02717:Iqgap3
|
APN |
3 |
88,005,666 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02971:Iqgap3
|
APN |
3 |
87,997,611 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL03079:Iqgap3
|
APN |
3 |
88,020,477 (GRCm39) |
missense |
probably benign |
|
|
IGL03240:Iqgap3
|
APN |
3 |
88,022,281 (GRCm39) |
missense |
probably benign |
0.00 |
|
adjutant
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Booster
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
peso_ligero
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0285:Iqgap3
|
UTSW |
3 |
88,004,297 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0442:Iqgap3
|
UTSW |
3 |
88,023,266 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0490:Iqgap3
|
UTSW |
3 |
88,021,363 (GRCm39) |
splice site |
probably benign |
|
|
R0569:Iqgap3
|
UTSW |
3 |
87,998,032 (GRCm39) |
splice site |
probably benign |
|
|
R0747:Iqgap3
|
UTSW |
3 |
88,014,810 (GRCm39) |
splice site |
probably benign |
|
|
R0843:Iqgap3
|
UTSW |
3 |
88,015,738 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1260:Iqgap3
|
UTSW |
3 |
88,021,330 (GRCm39) |
missense |
probably benign |
|
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1544:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1662:Iqgap3
|
UTSW |
3 |
88,005,708 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1686:Iqgap3
|
UTSW |
3 |
88,015,663 (GRCm39) |
splice site |
probably benign |
|
|
R1748:Iqgap3
|
UTSW |
3 |
88,021,287 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1836:Iqgap3
|
UTSW |
3 |
88,015,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1972:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R1973:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R2051:Iqgap3
|
UTSW |
3 |
88,027,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Iqgap3
|
UTSW |
3 |
88,023,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2352:Iqgap3
|
UTSW |
3 |
88,011,815 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2857:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R2859:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R3435:Iqgap3
|
UTSW |
3 |
88,001,911 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3522:Iqgap3
|
UTSW |
3 |
87,998,089 (GRCm39) |
missense |
probably null |
0.90 |
|
R4281:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4283:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4397:Iqgap3
|
UTSW |
3 |
88,011,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4414:Iqgap3
|
UTSW |
3 |
88,004,293 (GRCm39) |
missense |
probably benign |
|
|
R4660:Iqgap3
|
UTSW |
3 |
88,027,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4872:Iqgap3
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4883:Iqgap3
|
UTSW |
3 |
88,014,842 (GRCm39) |
missense |
probably benign |
|
|
R4915:Iqgap3
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5050:Iqgap3
|
UTSW |
3 |
87,997,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5130:Iqgap3
|
UTSW |
3 |
88,016,161 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5151:Iqgap3
|
UTSW |
3 |
88,025,067 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5645:Iqgap3
|
UTSW |
3 |
88,025,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5706:Iqgap3
|
UTSW |
3 |
88,023,215 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5748:Iqgap3
|
UTSW |
3 |
88,016,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5880:Iqgap3
|
UTSW |
3 |
88,024,509 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5982:Iqgap3
|
UTSW |
3 |
87,998,899 (GRCm39) |
nonsense |
probably null |
|
|
R6006:Iqgap3
|
UTSW |
3 |
87,998,854 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6026:Iqgap3
|
UTSW |
3 |
87,997,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6188:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6211:Iqgap3
|
UTSW |
3 |
87,998,822 (GRCm39) |
missense |
probably benign |
|
|
R6291:Iqgap3
|
UTSW |
3 |
87,997,037 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6344:Iqgap3
|
UTSW |
3 |
87,989,401 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6854:Iqgap3
|
UTSW |
3 |
88,004,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6877:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6958:Iqgap3
|
UTSW |
3 |
88,020,673 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7008:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R7050:Iqgap3
|
UTSW |
3 |
88,006,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7144:Iqgap3
|
UTSW |
3 |
88,024,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7170:Iqgap3
|
UTSW |
3 |
88,009,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Iqgap3
|
UTSW |
3 |
88,016,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Iqgap3
|
UTSW |
3 |
88,005,677 (GRCm39) |
missense |
probably benign |
|
|
R8008:Iqgap3
|
UTSW |
3 |
88,016,770 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8049:Iqgap3
|
UTSW |
3 |
88,011,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Iqgap3
|
UTSW |
3 |
88,001,957 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8190:Iqgap3
|
UTSW |
3 |
87,998,086 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8772:Iqgap3
|
UTSW |
3 |
87,997,144 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8878:Iqgap3
|
UTSW |
3 |
88,020,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Iqgap3
|
UTSW |
3 |
87,997,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9072:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9072:Iqgap3
|
UTSW |
3 |
87,998,883 (GRCm39) |
missense |
probably benign |
|
|
R9073:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9337:Iqgap3
|
UTSW |
3 |
88,023,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9489:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9593:Iqgap3
|
UTSW |
3 |
88,011,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Iqgap3
|
UTSW |
3 |
88,016,728 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9708:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9709:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9752:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9753:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9765:Iqgap3
|
UTSW |
3 |
88,017,361 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9771:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9772:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Iqgap3
|
UTSW |
3 |
87,996,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CATCACCTCCTGAGCATAGG -3'
(R):5'- TAGGTGTGTAACAACAGCTGCC -3'
Sequencing Primer
(F):5'- CCTGAGCATAGGGCCTTTTC -3'
(R):5'- GTGTAACAACAGCTGCCATCTCTG -3'
|
| Posted On |
2022-07-18 |
Incidental Mutation