Incidental Mutation 'R9497:Ncoa6'
| ID |
717261 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ncoa6
|
| Ensembl Gene |
ENSMUSG00000038369 |
| Gene Name |
nuclear receptor coactivator 6 |
| Synonyms |
ASC-2, RAP250, NRC, AIB3, ASC2, PRIP |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9497 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
155232585-155315741 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 155248238 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1689
(T1689A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000045386
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043126]
[ENSMUST00000109670]
[ENSMUST00000123293]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000043126
AA Change: T1689A
PolyPhen 2
Score 0.966 (Sensitivity: 0.77; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000045386
Gene: ENSMUSG00000038369
AA Change: T1689A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
47 |
190 |
3.3e-55 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
450 |
597 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
636 |
793 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
low complexity region
|
1543 |
1564 |
N/A |
INTRINSIC |
|
low complexity region
|
1578 |
1599 |
N/A |
INTRINSIC |
|
low complexity region
|
1607 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1808 |
1825 |
N/A |
INTRINSIC |
|
low complexity region
|
1894 |
1908 |
N/A |
INTRINSIC |
|
low complexity region
|
2043 |
2053 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000109670
AA Change: T1689A
PolyPhen 2
Score 0.966 (Sensitivity: 0.77; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000105295
Gene: ENSMUSG00000038369
AA Change: T1689A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
45 |
195 |
3.6e-60 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
450 |
597 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
636 |
793 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
low complexity region
|
1543 |
1564 |
N/A |
INTRINSIC |
|
low complexity region
|
1578 |
1599 |
N/A |
INTRINSIC |
|
low complexity region
|
1607 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1808 |
1825 |
N/A |
INTRINSIC |
|
low complexity region
|
1894 |
1908 |
N/A |
INTRINSIC |
|
low complexity region
|
2043 |
2053 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000123293
|
| SMART Domains |
Protein: ENSMUSP00000118113
Gene: ENSMUSG00000038369
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
45 |
195 |
2.4e-60 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
564 |
573 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygotes for targeted null mutations exhibit retarded embryonic growth and defects of the placenta, heart, liver, and nervous system. Mutants die around midgestation. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810459M11Rik |
A |
C |
1: 85,973,893 (GRCm39) |
E70A |
possibly damaging |
Het |
| Abcb5 |
C |
A |
12: 118,899,850 (GRCm39) |
Q272H |
probably damaging |
Het |
| Acoxl |
T |
C |
2: 127,719,706 (GRCm39) |
Y156H |
probably damaging |
Het |
| Alg9 |
T |
C |
9: 50,711,436 (GRCm39) |
F305L |
probably damaging |
Het |
| Apobec4 |
T |
C |
1: 152,632,947 (GRCm39) |
V325A |
probably benign |
Het |
| Aqp9 |
T |
G |
9: 71,069,651 (GRCm39) |
D46A |
probably benign |
Het |
| Atp13a4 |
T |
A |
16: 29,288,130 (GRCm39) |
|
probably null |
Het |
| BC051019 |
A |
G |
7: 109,315,466 (GRCm39) |
F263S |
probably damaging |
Het |
| Bicc1 |
A |
T |
10: 70,776,828 (GRCm39) |
|
probably null |
Het |
| Birc2 |
G |
A |
9: 7,861,028 (GRCm39) |
Q97* |
probably null |
Het |
| Capn13 |
G |
T |
17: 73,633,362 (GRCm39) |
T533N |
probably benign |
Het |
| Casp6 |
G |
A |
3: 129,699,559 (GRCm39) |
V13M |
probably benign |
Het |
| Cdh10 |
A |
T |
15: 18,964,267 (GRCm39) |
E143V |
probably damaging |
Het |
| Cobl |
T |
A |
11: 12,203,501 (GRCm39) |
Q1067L |
probably benign |
Het |
| Cr2 |
A |
G |
1: 194,850,743 (GRCm39) |
V241A |
probably damaging |
Het |
| Cyp2c23 |
C |
T |
19: 44,010,085 (GRCm39) |
V87M |
probably damaging |
Het |
| Cyp2j9 |
G |
A |
4: 96,460,211 (GRCm39) |
Q431* |
probably null |
Het |
| Cyp2t4 |
G |
A |
7: 26,854,717 (GRCm39) |
V66M |
possibly damaging |
Het |
| Cyp4a12b |
A |
T |
4: 115,271,768 (GRCm39) |
M160L |
probably benign |
Het |
| Ddhd2 |
T |
A |
8: 26,217,731 (GRCm39) |
K715N |
possibly damaging |
Het |
| Ecscr |
T |
C |
18: 35,851,436 (GRCm39) |
Y32C |
probably damaging |
Het |
| Ednra |
A |
T |
8: 78,446,934 (GRCm39) |
L48Q |
probably benign |
Het |
| Eya4 |
C |
T |
10: 22,987,458 (GRCm39) |
|
probably null |
Het |
| F13a1 |
C |
A |
13: 37,082,118 (GRCm39) |
V529L |
probably benign |
Het |
| Fam151b |
A |
T |
13: 92,610,621 (GRCm39) |
I56K |
probably damaging |
Het |
| Fat3 |
A |
G |
9: 15,903,504 (GRCm39) |
I2997T |
probably damaging |
Het |
| Fgfr2 |
A |
T |
7: 129,765,763 (GRCm39) |
F817I |
probably damaging |
Het |
| Fras1 |
G |
T |
5: 96,884,895 (GRCm39) |
C2591F |
probably damaging |
Het |
| Fryl |
T |
C |
5: 73,215,134 (GRCm39) |
D2214G |
|
Het |
| Galntl6 |
A |
T |
8: 58,290,410 (GRCm39) |
D394E |
probably damaging |
Het |
| Ggcx |
C |
A |
6: 72,406,190 (GRCm39) |
N605K |
probably damaging |
Het |
| Gja5 |
A |
G |
3: 96,958,801 (GRCm39) |
N286S |
|
Het |
| Gm4553 |
A |
T |
7: 141,719,298 (GRCm39) |
C43* |
probably null |
Het |
| Gpr158 |
T |
C |
2: 21,831,825 (GRCm39) |
V975A |
probably benign |
Het |
| Greb1l |
T |
A |
18: 10,458,600 (GRCm39) |
D60E |
probably benign |
Het |
| Hao2 |
A |
T |
3: 98,784,462 (GRCm39) |
L301H |
probably damaging |
Het |
| Hic1 |
A |
G |
11: 75,060,131 (GRCm39) |
L72P |
possibly damaging |
Het |
| Hs3st5 |
A |
C |
10: 36,709,370 (GRCm39) |
N302H |
probably benign |
Het |
| Htr1d |
A |
G |
4: 136,169,663 (GRCm39) |
|
probably benign |
Het |
| Inka1 |
A |
G |
9: 107,861,938 (GRCm39) |
V128A |
probably benign |
Het |
| Kdm7a |
T |
C |
6: 39,128,253 (GRCm39) |
D526G |
probably damaging |
Het |
| Kif5a |
T |
C |
10: 127,079,353 (GRCm39) |
S282G |
probably damaging |
Het |
| Klhdc7b |
T |
C |
15: 89,272,463 (GRCm39) |
V457A |
possibly damaging |
Het |
| Lcorl |
A |
G |
5: 45,891,339 (GRCm39) |
V421A |
probably benign |
Het |
| Ltc4s |
A |
G |
11: 50,127,386 (GRCm39) |
S150P |
unknown |
Het |
| Mdfic |
C |
T |
6: 15,720,852 (GRCm39) |
R18W |
unknown |
Het |
| Mdfic |
T |
G |
6: 15,770,508 (GRCm39) |
D171E |
probably benign |
Het |
| Meis2 |
T |
C |
2: 115,694,724 (GRCm39) |
D473G |
possibly damaging |
Het |
| Mettl17 |
A |
T |
14: 52,129,029 (GRCm39) |
Q433L |
unknown |
Het |
| Mettl25 |
T |
C |
10: 105,677,090 (GRCm39) |
R31G |
probably damaging |
Het |
| Mroh2b |
T |
A |
15: 4,950,845 (GRCm39) |
I581N |
probably damaging |
Het |
| Myh7 |
A |
T |
14: 55,217,841 (GRCm39) |
N1091K |
probably benign |
Het |
| Mysm1 |
T |
C |
4: 94,848,635 (GRCm39) |
D466G |
probably benign |
Het |
| Ndfip2 |
A |
G |
14: 105,542,245 (GRCm39) |
T332A |
probably benign |
Het |
| Nfkbil1 |
G |
A |
17: 35,439,605 (GRCm39) |
P303S |
probably damaging |
Het |
| Nfx1 |
T |
G |
4: 40,994,104 (GRCm39) |
N604K |
probably benign |
Het |
| Npb |
T |
C |
11: 120,499,473 (GRCm39) |
F47L |
probably benign |
Het |
| Nr2c2 |
C |
T |
6: 92,133,673 (GRCm39) |
T259I |
possibly damaging |
Het |
| Nt5el |
G |
T |
13: 105,236,987 (GRCm39) |
L79F |
probably damaging |
Het |
| Obsl1 |
C |
T |
1: 75,467,484 (GRCm39) |
C1430Y |
probably damaging |
Het |
| Or10al5 |
T |
A |
17: 38,062,942 (GRCm39) |
Y66N |
probably damaging |
Het |
| Or10b1 |
A |
G |
10: 78,355,738 (GRCm39) |
I99V |
probably benign |
Het |
| Or10g6 |
A |
T |
9: 39,934,616 (GRCm39) |
H309L |
probably benign |
Het |
| Or4d5 |
G |
A |
9: 40,011,935 (GRCm39) |
P284S |
probably damaging |
Het |
| Or4n4b |
C |
T |
14: 50,536,362 (GRCm39) |
V135I |
probably benign |
Het |
| Or6c202 |
C |
A |
10: 128,996,464 (GRCm39) |
V130L |
probably benign |
Het |
| Or6f1 |
G |
A |
7: 85,970,989 (GRCm39) |
T57M |
probably damaging |
Het |
| Pdcd6 |
A |
T |
13: 74,453,695 (GRCm39) |
F148I |
probably damaging |
Het |
| Pih1d1 |
A |
T |
7: 44,803,789 (GRCm39) |
Q16L |
unknown |
Het |
| Ppp1r10 |
T |
C |
17: 36,235,786 (GRCm39) |
S123P |
probably damaging |
Het |
| Ppp1r13b |
A |
T |
12: 111,807,446 (GRCm39) |
M305K |
probably benign |
Het |
| Prg2 |
A |
G |
2: 84,811,685 (GRCm39) |
K2E |
possibly damaging |
Het |
| Prkd1 |
A |
T |
12: 50,438,107 (GRCm39) |
|
probably null |
Het |
| Rfx7 |
T |
A |
9: 72,526,423 (GRCm39) |
H1204Q |
probably benign |
Het |
| Serpina3k |
A |
C |
12: 104,309,430 (GRCm39) |
Q291H |
probably benign |
Het |
| Tafa4 |
T |
A |
6: 96,820,831 (GRCm39) |
I93F |
possibly damaging |
Het |
| Tas2r107 |
G |
T |
6: 131,636,549 (GRCm39) |
Q167K |
probably benign |
Het |
| Tle1 |
A |
C |
4: 72,071,135 (GRCm39) |
|
probably benign |
Het |
| Tm7sf3 |
C |
T |
6: 146,525,179 (GRCm39) |
D89N |
possibly damaging |
Het |
| Trpa1 |
C |
T |
1: 14,989,026 (GRCm39) |
E12K |
probably benign |
Het |
| Vmn2r7 |
T |
C |
3: 64,614,474 (GRCm39) |
T447A |
probably benign |
Het |
| Wdr86 |
T |
C |
5: 24,920,538 (GRCm39) |
Y283C |
probably benign |
Het |
| Zfp329 |
A |
T |
7: 12,544,215 (GRCm39) |
Y436* |
probably null |
Het |
|
| Other mutations in Ncoa6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:Ncoa6
|
APN |
2 |
155,248,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00849:Ncoa6
|
APN |
2 |
155,263,608 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL00933:Ncoa6
|
APN |
2 |
155,257,317 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00981:Ncoa6
|
APN |
2 |
155,248,099 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01420:Ncoa6
|
APN |
2 |
155,249,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02160:Ncoa6
|
APN |
2 |
155,263,003 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL03049:Ncoa6
|
APN |
2 |
155,260,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03194:Ncoa6
|
APN |
2 |
155,257,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03269:Ncoa6
|
APN |
2 |
155,248,409 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03299:Ncoa6
|
APN |
2 |
155,249,207 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03306:Ncoa6
|
APN |
2 |
155,247,427 (GRCm39) |
missense |
probably benign |
0.30 |
|
alcoa
|
UTSW |
2 |
155,244,584 (GRCm39) |
unclassified |
probably benign |
|
|
Aluminum
|
UTSW |
2 |
155,241,613 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
balboa
|
UTSW |
2 |
155,248,869 (GRCm39) |
missense |
probably benign |
0.05 |
|
mauna_loa
|
UTSW |
2 |
155,257,147 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4466001:Ncoa6
|
UTSW |
2 |
155,247,577 (GRCm39) |
missense |
probably benign |
|
|
R0011:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0014:Ncoa6
|
UTSW |
2 |
155,279,963 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0079:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0080:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0081:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0164:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0166:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0172:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0173:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0245:Ncoa6
|
UTSW |
2 |
155,233,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0284:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0285:Ncoa6
|
UTSW |
2 |
155,257,621 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0285:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0288:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0539:Ncoa6
|
UTSW |
2 |
155,257,617 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0652:Ncoa6
|
UTSW |
2 |
155,233,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0781:Ncoa6
|
UTSW |
2 |
155,253,440 (GRCm39) |
splice site |
probably benign |
|
|
R1053:Ncoa6
|
UTSW |
2 |
155,275,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1110:Ncoa6
|
UTSW |
2 |
155,253,440 (GRCm39) |
splice site |
probably benign |
|
|
R1420:Ncoa6
|
UTSW |
2 |
155,263,073 (GRCm39) |
nonsense |
probably null |
|
|
R1521:Ncoa6
|
UTSW |
2 |
155,257,142 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1541:Ncoa6
|
UTSW |
2 |
155,257,224 (GRCm39) |
missense |
probably benign |
0.35 |
|
R1677:Ncoa6
|
UTSW |
2 |
155,244,584 (GRCm39) |
unclassified |
probably benign |
|
|
R1858:Ncoa6
|
UTSW |
2 |
155,263,559 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1954:Ncoa6
|
UTSW |
2 |
155,248,741 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1955:Ncoa6
|
UTSW |
2 |
155,248,741 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2040:Ncoa6
|
UTSW |
2 |
155,248,000 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2087:Ncoa6
|
UTSW |
2 |
155,248,079 (GRCm39) |
nonsense |
probably null |
|
|
R2159:Ncoa6
|
UTSW |
2 |
155,249,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2278:Ncoa6
|
UTSW |
2 |
155,249,570 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2696:Ncoa6
|
UTSW |
2 |
155,279,935 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2891:Ncoa6
|
UTSW |
2 |
155,279,881 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3618:Ncoa6
|
UTSW |
2 |
155,249,709 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3747:Ncoa6
|
UTSW |
2 |
155,253,561 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3778:Ncoa6
|
UTSW |
2 |
155,263,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3784:Ncoa6
|
UTSW |
2 |
155,249,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3802:Ncoa6
|
UTSW |
2 |
155,247,484 (GRCm39) |
missense |
probably benign |
|
|
R3820:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3821:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3822:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3870:Ncoa6
|
UTSW |
2 |
155,257,477 (GRCm39) |
splice site |
probably null |
|
|
R4037:Ncoa6
|
UTSW |
2 |
155,249,290 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4488:Ncoa6
|
UTSW |
2 |
155,249,396 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4719:Ncoa6
|
UTSW |
2 |
155,233,081 (GRCm39) |
unclassified |
probably benign |
|
|
R4732:Ncoa6
|
UTSW |
2 |
155,263,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4733:Ncoa6
|
UTSW |
2 |
155,263,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4829:Ncoa6
|
UTSW |
2 |
155,257,147 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4835:Ncoa6
|
UTSW |
2 |
155,249,053 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4883:Ncoa6
|
UTSW |
2 |
155,248,687 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4967:Ncoa6
|
UTSW |
2 |
155,263,252 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5021:Ncoa6
|
UTSW |
2 |
155,248,869 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5234:Ncoa6
|
UTSW |
2 |
155,279,933 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5356:Ncoa6
|
UTSW |
2 |
155,263,112 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5358:Ncoa6
|
UTSW |
2 |
155,248,907 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5375:Ncoa6
|
UTSW |
2 |
155,275,915 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5412:Ncoa6
|
UTSW |
2 |
155,249,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5579:Ncoa6
|
UTSW |
2 |
155,248,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5618:Ncoa6
|
UTSW |
2 |
155,279,817 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5641:Ncoa6
|
UTSW |
2 |
155,263,756 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5757:Ncoa6
|
UTSW |
2 |
155,253,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Ncoa6
|
UTSW |
2 |
155,250,061 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5778:Ncoa6
|
UTSW |
2 |
155,248,688 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5852:Ncoa6
|
UTSW |
2 |
155,247,419 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5940:Ncoa6
|
UTSW |
2 |
155,257,785 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6155:Ncoa6
|
UTSW |
2 |
155,249,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6374:Ncoa6
|
UTSW |
2 |
155,263,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6389:Ncoa6
|
UTSW |
2 |
155,237,736 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6669:Ncoa6
|
UTSW |
2 |
155,241,613 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7097:Ncoa6
|
UTSW |
2 |
155,279,983 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7385:Ncoa6
|
UTSW |
2 |
155,249,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7963:Ncoa6
|
UTSW |
2 |
155,247,916 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8356:Ncoa6
|
UTSW |
2 |
155,248,172 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8698:Ncoa6
|
UTSW |
2 |
155,257,041 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8859:Ncoa6
|
UTSW |
2 |
155,248,388 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R8870:Ncoa6
|
UTSW |
2 |
155,263,078 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9041:Ncoa6
|
UTSW |
2 |
155,257,450 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9062:Ncoa6
|
UTSW |
2 |
155,263,348 (GRCm39) |
missense |
probably benign |
0.42 |
|
R9088:Ncoa6
|
UTSW |
2 |
155,249,726 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9225:Ncoa6
|
UTSW |
2 |
155,249,441 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9445:Ncoa6
|
UTSW |
2 |
155,250,063 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9514:Ncoa6
|
UTSW |
2 |
155,248,133 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9656:Ncoa6
|
UTSW |
2 |
155,274,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9720:Ncoa6
|
UTSW |
2 |
155,250,304 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9732:Ncoa6
|
UTSW |
2 |
155,244,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
RF033:Ncoa6
|
UTSW |
2 |
155,263,651 (GRCm39) |
small deletion |
probably benign |
|
|
RF040:Ncoa6
|
UTSW |
2 |
155,263,651 (GRCm39) |
small deletion |
probably benign |
|
|
RF048:Ncoa6
|
UTSW |
2 |
155,263,632 (GRCm39) |
small deletion |
probably benign |
|
|
X0017:Ncoa6
|
UTSW |
2 |
155,248,460 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1176:Ncoa6
|
UTSW |
2 |
155,263,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Ncoa6
|
UTSW |
2 |
155,263,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ncoa6
|
UTSW |
2 |
155,248,062 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTGCTGGACAGAAGGATTAGG -3'
(R):5'- GTCAACAGTCGTCACAATGCC -3'
Sequencing Primer
(F):5'- CGACAACTGGAGAGGATGTAC -3'
(R):5'- GTCGTCACAATGCCCAACGTG -3'
|
| Posted On |
2022-07-18 |
Incidental Mutation