Incidental Mutation 'R9510:Dapk1'
| ID |
718121 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dapk1
|
| Ensembl Gene |
ENSMUSG00000021559 |
| Gene Name |
death associated protein kinase 1 |
| Synonyms |
DAP-Kinase, D13Ucla1, 2810425C21Rik, 2310039H24Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9510 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
60749761-60911005 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 60910203 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 1441
(D1441V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000153607
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044083]
[ENSMUST00000077453]
[ENSMUST00000226059]
|
| AlphaFold |
Q80YE7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000044083
|
| SMART Domains |
Protein: ENSMUSP00000040825
Gene: ENSMUSG00000021559
| Domain | Start | End | E-Value | Type |
|---|
|
S_TKc
|
13 |
275 |
6.35e-99 |
SMART |
|
low complexity region
|
295 |
306 |
N/A |
INTRINSIC |
|
ANK
|
378 |
407 |
5.09e-2 |
SMART |
|
ANK
|
411 |
440 |
6.61e-1 |
SMART |
|
ANK
|
444 |
473 |
7.64e-6 |
SMART |
|
ANK
|
477 |
506 |
2.13e-4 |
SMART |
|
ANK
|
510 |
539 |
1.31e-4 |
SMART |
|
ANK
|
543 |
572 |
7.83e-3 |
SMART |
|
ANK
|
576 |
605 |
8.52e-4 |
SMART |
|
ANK
|
609 |
638 |
1.85e-4 |
SMART |
|
ANK
|
642 |
671 |
7.29e2 |
SMART |
|
low complexity region
|
711 |
725 |
N/A |
INTRINSIC |
|
DEATH
|
1299 |
1396 |
2.65e-18 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000077453
|
| SMART Domains |
Protein: ENSMUSP00000076666
Gene: ENSMUSG00000021559
| Domain | Start | End | E-Value | Type |
|---|
|
S_TKc
|
13 |
275 |
6.35e-99 |
SMART |
|
low complexity region
|
295 |
306 |
N/A |
INTRINSIC |
|
ANK
|
378 |
407 |
5.09e-2 |
SMART |
|
ANK
|
411 |
440 |
6.61e-1 |
SMART |
|
ANK
|
444 |
473 |
7.64e-6 |
SMART |
|
ANK
|
477 |
506 |
2.13e-4 |
SMART |
|
ANK
|
510 |
539 |
1.31e-4 |
SMART |
|
ANK
|
543 |
572 |
7.83e-3 |
SMART |
|
ANK
|
576 |
605 |
8.52e-4 |
SMART |
|
ANK
|
609 |
638 |
1.85e-4 |
SMART |
|
ANK
|
642 |
671 |
7.29e2 |
SMART |
|
low complexity region
|
711 |
725 |
N/A |
INTRINSIC |
|
Pfam:COR
|
984 |
1176 |
4.2e-10 |
PFAM |
|
DEATH
|
1299 |
1396 |
2.65e-18 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000226059
AA Change: D1441V
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
PHENOTYPE: Mice homozygous for a knock-out allele show decreased sensitivity to ER stress-induced cell death and reduced tunicamycin-induced kidney damage. Mice homozygous for a gene trapped allele show decreased infarct size and neuronal death with improved neurological scores after ischemic brain injury. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930578G10Rik |
T |
G |
4: 42,760,998 (GRCm39) |
W6G |
unknown |
Het |
| Aatk |
A |
T |
11: 119,901,094 (GRCm39) |
C1101S |
probably benign |
Het |
| Ankrd61 |
T |
C |
5: 143,828,322 (GRCm39) |
T218A |
possibly damaging |
Het |
| Cacna1b |
T |
C |
2: 24,540,058 (GRCm39) |
E1467G |
probably damaging |
Het |
| Ccdc186 |
T |
C |
19: 56,802,016 (GRCm39) |
T34A |
probably benign |
Het |
| Cdc42bpb |
G |
A |
12: 111,261,372 (GRCm39) |
P1656S |
probably benign |
Het |
| Cdk13 |
A |
C |
13: 17,902,747 (GRCm39) |
C934W |
probably damaging |
Het |
| Cebpg |
T |
C |
7: 34,750,080 (GRCm39) |
N61S |
probably benign |
Het |
| Cldn13 |
T |
A |
5: 134,943,843 (GRCm39) |
E114V |
probably benign |
Het |
| Clec9a |
T |
A |
6: 129,398,023 (GRCm39) |
I187K |
possibly damaging |
Het |
| Cr2 |
G |
T |
1: 194,840,416 (GRCm39) |
L509M |
probably damaging |
Het |
| Creb3l2 |
C |
A |
6: 37,311,446 (GRCm39) |
G448W |
probably damaging |
Het |
| Csf2rb |
T |
A |
15: 78,229,760 (GRCm39) |
|
probably null |
Het |
| Cyth1 |
C |
T |
11: 118,076,206 (GRCm39) |
|
probably null |
Het |
| Dnhd1 |
A |
T |
7: 105,352,889 (GRCm39) |
N2681Y |
possibly damaging |
Het |
| Dnm1 |
T |
C |
2: 32,213,739 (GRCm39) |
M476V |
probably benign |
Het |
| Dock1 |
T |
G |
7: 134,592,279 (GRCm39) |
I938S |
probably benign |
Het |
| Duox1 |
G |
A |
2: 122,160,023 (GRCm39) |
V713I |
possibly damaging |
Het |
| Dusp16 |
T |
C |
6: 134,695,226 (GRCm39) |
H535R |
probably benign |
Het |
| Eif3j2 |
TGCCGCCGCCGCCGCCGCCGCCGCCGCC |
TGCCGCCGCCGCCGCCGCCGCCGCC |
18: 43,610,782 (GRCm39) |
|
probably benign |
Het |
| Fancd2os |
T |
A |
6: 113,574,994 (GRCm39) |
Y4F |
probably damaging |
Het |
| Fat4 |
A |
T |
3: 39,037,886 (GRCm39) |
Q3846L |
probably benign |
Het |
| Fbxw10 |
A |
C |
11: 62,743,814 (GRCm39) |
H240P |
probably benign |
Het |
| Fer1l5 |
T |
C |
1: 36,442,662 (GRCm39) |
L727P |
probably damaging |
Het |
| Fezf1 |
A |
C |
6: 23,247,845 (GRCm39) |
F77V |
probably benign |
Het |
| Fli1 |
T |
C |
9: 32,335,493 (GRCm39) |
D313G |
probably damaging |
Het |
| Frmd4a |
A |
G |
2: 4,608,324 (GRCm39) |
T731A |
probably benign |
Het |
| Gfy |
T |
C |
7: 44,828,090 (GRCm39) |
Q2R |
possibly damaging |
Het |
| Ggt5 |
T |
C |
10: 75,445,139 (GRCm39) |
V382A |
probably benign |
Het |
| Hira |
A |
G |
16: 18,772,789 (GRCm39) |
D867G |
probably damaging |
Het |
| Hmcn1 |
A |
G |
1: 150,462,127 (GRCm39) |
S5184P |
probably benign |
Het |
| Ighv1-26 |
A |
C |
12: 114,752,407 (GRCm39) |
F7V |
probably benign |
Het |
| Igkv4-81 |
C |
T |
6: 68,967,796 (GRCm39) |
E102K |
possibly damaging |
Het |
| Inmt |
G |
T |
6: 55,147,990 (GRCm39) |
S213Y |
possibly damaging |
Het |
| Ints2 |
T |
A |
11: 86,135,335 (GRCm39) |
M360L |
probably benign |
Het |
| Itih3 |
A |
G |
14: 30,631,416 (GRCm39) |
S827P |
probably benign |
Het |
| Kcnk12 |
C |
A |
17: 88,054,122 (GRCm39) |
R180L |
probably benign |
Het |
| Klhl2 |
T |
C |
8: 65,202,113 (GRCm39) |
N521S |
probably benign |
Het |
| Kmt2a |
A |
T |
9: 44,734,531 (GRCm39) |
F2104I |
unknown |
Het |
| Kndc1 |
G |
A |
7: 139,510,031 (GRCm39) |
S1291N |
probably benign |
Het |
| Mettl21a |
T |
C |
1: 64,647,285 (GRCm39) |
T91A |
probably damaging |
Het |
| Mmrn2 |
A |
G |
14: 34,120,407 (GRCm39) |
I426V |
possibly damaging |
Het |
| Mrpl2 |
T |
C |
17: 46,958,440 (GRCm39) |
V74A |
probably benign |
Het |
| Msantd4 |
A |
G |
9: 4,385,007 (GRCm39) |
D244G |
probably benign |
Het |
| Mtfmt |
C |
T |
9: 65,343,147 (GRCm39) |
R18C |
probably benign |
Het |
| Ncam2 |
A |
G |
16: 81,420,341 (GRCm39) |
*838W |
probably null |
Het |
| Ncor1 |
CTG |
CTGATG |
11: 62,324,442 (GRCm39) |
|
probably benign |
Het |
| Nsf |
T |
C |
11: 103,763,988 (GRCm39) |
N365S |
probably damaging |
Het |
| Osbpl3 |
C |
T |
6: 50,313,194 (GRCm39) |
|
probably null |
Het |
| Pam |
C |
T |
1: 97,826,065 (GRCm39) |
|
probably null |
Het |
| Parn |
A |
T |
16: 13,358,942 (GRCm39) |
M600K |
probably benign |
Het |
| Pcdha11 |
C |
A |
18: 37,139,532 (GRCm39) |
T387N |
probably benign |
Het |
| Ptprt |
A |
C |
2: 161,397,381 (GRCm39) |
C1129G |
probably damaging |
Het |
| Ralgapb |
T |
A |
2: 158,285,856 (GRCm39) |
S645T |
probably damaging |
Het |
| Rara |
C |
T |
11: 98,860,983 (GRCm39) |
S157L |
probably benign |
Het |
| Rnf40 |
T |
A |
7: 127,201,808 (GRCm39) |
I1000N |
probably damaging |
Het |
| Sap25 |
C |
T |
5: 137,640,494 (GRCm39) |
T141I |
probably null |
Het |
| Scube2 |
C |
T |
7: 109,430,969 (GRCm39) |
G410E |
probably damaging |
Het |
| Sh3gl2 |
A |
G |
4: 85,304,089 (GRCm39) |
E264G |
probably benign |
Het |
| Smc4 |
T |
G |
3: 68,914,662 (GRCm39) |
S92A |
probably damaging |
Het |
| Sorcs1 |
C |
T |
19: 50,666,521 (GRCm39) |
R129Q |
probably benign |
Het |
| Spata31e4 |
A |
G |
13: 50,856,149 (GRCm39) |
T596A |
possibly damaging |
Het |
| Spef2 |
T |
C |
15: 9,713,203 (GRCm39) |
R390G |
probably damaging |
Het |
| Speg |
T |
C |
1: 75,377,768 (GRCm39) |
F842S |
probably damaging |
Het |
| Stk17b |
G |
T |
1: 53,796,898 (GRCm39) |
H290N |
probably damaging |
Het |
| Stpg3 |
A |
T |
2: 25,103,516 (GRCm39) |
V191D |
probably benign |
Het |
| Supt6 |
C |
T |
11: 78,120,290 (GRCm39) |
R350H |
probably damaging |
Het |
| Taf1b |
G |
A |
12: 24,566,947 (GRCm39) |
A214T |
possibly damaging |
Het |
| Tet3 |
T |
C |
6: 83,380,935 (GRCm39) |
E411G |
possibly damaging |
Het |
| Tet3 |
T |
A |
6: 83,381,808 (GRCm39) |
|
probably null |
Het |
| Tg |
T |
C |
15: 66,545,913 (GRCm39) |
Y212H |
probably damaging |
Het |
| Tns3 |
A |
G |
11: 8,395,702 (GRCm39) |
I1234T |
probably damaging |
Het |
| Traf6 |
C |
T |
2: 101,521,825 (GRCm39) |
T220I |
possibly damaging |
Het |
| Tram2 |
C |
G |
1: 21,074,150 (GRCm39) |
A263P |
possibly damaging |
Het |
| Treml1 |
T |
G |
17: 48,673,771 (GRCm39) |
S261A |
probably damaging |
Het |
| Trim34b |
A |
G |
7: 103,980,503 (GRCm39) |
E197G |
probably damaging |
Het |
| Tspan18 |
C |
T |
2: 93,050,462 (GRCm39) |
G54S |
probably damaging |
Het |
| Wdtc1 |
A |
G |
4: 133,049,529 (GRCm39) |
V29A |
probably damaging |
Het |
| Zdhhc16 |
T |
C |
19: 41,929,155 (GRCm39) |
Y253H |
probably damaging |
Het |
| Zfp366 |
A |
G |
13: 99,365,874 (GRCm39) |
Y345C |
probably damaging |
Het |
| Zfp423 |
T |
A |
8: 88,510,041 (GRCm39) |
D101V |
possibly damaging |
Het |
| Zfp462 |
G |
A |
4: 55,080,735 (GRCm39) |
M2450I |
probably benign |
Het |
| Zfp52 |
C |
T |
17: 21,782,218 (GRCm39) |
L689F |
possibly damaging |
Het |
| Zim1 |
G |
A |
7: 6,690,739 (GRCm39) |
Q29* |
probably null |
Het |
|
| Other mutations in Dapk1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:Dapk1
|
APN |
13 |
60,908,854 (GRCm39) |
missense |
probably benign |
0.23 |
|
IGL00500:Dapk1
|
APN |
13 |
60,908,618 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00801:Dapk1
|
APN |
13 |
60,909,062 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00903:Dapk1
|
APN |
13 |
60,909,211 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01468:Dapk1
|
APN |
13 |
60,908,612 (GRCm39) |
missense |
probably benign |
|
|
IGL01535:Dapk1
|
APN |
13 |
60,878,845 (GRCm39) |
splice site |
probably benign |
|
|
IGL01755:Dapk1
|
APN |
13 |
60,908,990 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL01755:Dapk1
|
APN |
13 |
60,908,989 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01862:Dapk1
|
APN |
13 |
60,874,424 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL01985:Dapk1
|
APN |
13 |
60,884,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02124:Dapk1
|
APN |
13 |
60,878,696 (GRCm39) |
missense |
probably benign |
|
|
IGL02376:Dapk1
|
APN |
13 |
60,844,208 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02449:Dapk1
|
APN |
13 |
60,867,584 (GRCm39) |
splice site |
probably benign |
|
|
IGL02490:Dapk1
|
APN |
13 |
60,897,148 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02503:Dapk1
|
APN |
13 |
60,909,621 (GRCm39) |
nonsense |
probably null |
|
|
IGL02516:Dapk1
|
APN |
13 |
60,844,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02544:Dapk1
|
APN |
13 |
60,899,031 (GRCm39) |
missense |
probably benign |
|
|
IGL02604:Dapk1
|
APN |
13 |
60,896,134 (GRCm39) |
missense |
probably benign |
|
|
IGL03035:Dapk1
|
APN |
13 |
60,864,587 (GRCm39) |
missense |
probably damaging |
0.99 |
|
H8562:Dapk1
|
UTSW |
13 |
60,909,126 (GRCm39) |
missense |
probably damaging |
0.98 |
|
P0026:Dapk1
|
UTSW |
13 |
60,865,963 (GRCm39) |
splice site |
probably benign |
|
|
R0116:Dapk1
|
UTSW |
13 |
60,908,914 (GRCm39) |
missense |
probably benign |
|
|
R0165:Dapk1
|
UTSW |
13 |
60,909,407 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0357:Dapk1
|
UTSW |
13 |
60,877,372 (GRCm39) |
nonsense |
probably null |
|
|
R0446:Dapk1
|
UTSW |
13 |
60,873,101 (GRCm39) |
splice site |
probably null |
|
|
R0502:Dapk1
|
UTSW |
13 |
60,878,662 (GRCm39) |
splice site |
probably null |
|
|
R0503:Dapk1
|
UTSW |
13 |
60,878,662 (GRCm39) |
splice site |
probably null |
|
|
R0597:Dapk1
|
UTSW |
13 |
60,909,198 (GRCm39) |
missense |
probably benign |
0.40 |
|
R0614:Dapk1
|
UTSW |
13 |
60,865,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0751:Dapk1
|
UTSW |
13 |
60,844,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0930:Dapk1
|
UTSW |
13 |
60,905,262 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1023:Dapk1
|
UTSW |
13 |
60,878,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1033:Dapk1
|
UTSW |
13 |
60,869,679 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1101:Dapk1
|
UTSW |
13 |
60,864,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1184:Dapk1
|
UTSW |
13 |
60,844,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1430:Dapk1
|
UTSW |
13 |
60,901,957 (GRCm39) |
missense |
probably benign |
0.28 |
|
R1630:Dapk1
|
UTSW |
13 |
60,877,345 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1681:Dapk1
|
UTSW |
13 |
60,866,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1799:Dapk1
|
UTSW |
13 |
60,867,468 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2012:Dapk1
|
UTSW |
13 |
60,869,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2068:Dapk1
|
UTSW |
13 |
60,899,022 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Dapk1
|
UTSW |
13 |
60,909,481 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2131:Dapk1
|
UTSW |
13 |
60,877,345 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2154:Dapk1
|
UTSW |
13 |
60,877,317 (GRCm39) |
missense |
probably benign |
0.36 |
|
R2288:Dapk1
|
UTSW |
13 |
60,909,563 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2312:Dapk1
|
UTSW |
13 |
60,905,167 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2362:Dapk1
|
UTSW |
13 |
60,878,745 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2400:Dapk1
|
UTSW |
13 |
60,900,030 (GRCm39) |
missense |
probably benign |
0.34 |
|
R2909:Dapk1
|
UTSW |
13 |
60,864,631 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2926:Dapk1
|
UTSW |
13 |
60,867,564 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R3741:Dapk1
|
UTSW |
13 |
60,896,014 (GRCm39) |
missense |
probably benign |
0.09 |
|
R3810:Dapk1
|
UTSW |
13 |
60,908,503 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4374:Dapk1
|
UTSW |
13 |
60,867,498 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4375:Dapk1
|
UTSW |
13 |
60,909,403 (GRCm39) |
missense |
probably benign |
|
|
R4377:Dapk1
|
UTSW |
13 |
60,867,498 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4490:Dapk1
|
UTSW |
13 |
60,865,942 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4576:Dapk1
|
UTSW |
13 |
60,869,636 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4599:Dapk1
|
UTSW |
13 |
60,865,861 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4682:Dapk1
|
UTSW |
13 |
60,898,961 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4717:Dapk1
|
UTSW |
13 |
60,874,476 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4775:Dapk1
|
UTSW |
13 |
60,897,156 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4790:Dapk1
|
UTSW |
13 |
60,870,919 (GRCm39) |
frame shift |
probably null |
|
|
R4897:Dapk1
|
UTSW |
13 |
60,909,600 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4931:Dapk1
|
UTSW |
13 |
60,908,774 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5113:Dapk1
|
UTSW |
13 |
60,869,592 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5503:Dapk1
|
UTSW |
13 |
60,873,126 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5948:Dapk1
|
UTSW |
13 |
60,877,209 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6012:Dapk1
|
UTSW |
13 |
60,909,476 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6035:Dapk1
|
UTSW |
13 |
60,909,013 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6035:Dapk1
|
UTSW |
13 |
60,909,013 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6268:Dapk1
|
UTSW |
13 |
60,909,580 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6330:Dapk1
|
UTSW |
13 |
60,909,140 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6331:Dapk1
|
UTSW |
13 |
60,877,256 (GRCm39) |
nonsense |
probably null |
|
|
R6553:Dapk1
|
UTSW |
13 |
60,908,975 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6598:Dapk1
|
UTSW |
13 |
60,909,161 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6602:Dapk1
|
UTSW |
13 |
60,897,018 (GRCm39) |
missense |
probably benign |
0.20 |
|
R6640:Dapk1
|
UTSW |
13 |
60,864,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6684:Dapk1
|
UTSW |
13 |
60,908,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6747:Dapk1
|
UTSW |
13 |
60,873,154 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6799:Dapk1
|
UTSW |
13 |
60,900,049 (GRCm39) |
missense |
probably benign |
|
|
R6809:Dapk1
|
UTSW |
13 |
60,899,103 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6915:Dapk1
|
UTSW |
13 |
60,844,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6949:Dapk1
|
UTSW |
13 |
60,884,138 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6979:Dapk1
|
UTSW |
13 |
60,896,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7161:Dapk1
|
UTSW |
13 |
60,844,209 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7171:Dapk1
|
UTSW |
13 |
60,909,599 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7199:Dapk1
|
UTSW |
13 |
60,902,024 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7203:Dapk1
|
UTSW |
13 |
60,844,149 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7404:Dapk1
|
UTSW |
13 |
60,867,455 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7448:Dapk1
|
UTSW |
13 |
60,898,990 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7480:Dapk1
|
UTSW |
13 |
60,905,311 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7532:Dapk1
|
UTSW |
13 |
60,878,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7574:Dapk1
|
UTSW |
13 |
60,908,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7711:Dapk1
|
UTSW |
13 |
60,909,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7753:Dapk1
|
UTSW |
13 |
60,899,007 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R7804:Dapk1
|
UTSW |
13 |
60,873,153 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7822:Dapk1
|
UTSW |
13 |
60,873,715 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7973:Dapk1
|
UTSW |
13 |
60,909,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8103:Dapk1
|
UTSW |
13 |
60,897,009 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8121:Dapk1
|
UTSW |
13 |
60,909,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8245:Dapk1
|
UTSW |
13 |
60,878,710 (GRCm39) |
missense |
probably benign |
|
|
R8401:Dapk1
|
UTSW |
13 |
60,870,904 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8419:Dapk1
|
UTSW |
13 |
60,887,911 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8926:Dapk1
|
UTSW |
13 |
60,908,734 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9063:Dapk1
|
UTSW |
13 |
60,866,264 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9131:Dapk1
|
UTSW |
13 |
60,909,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9176:Dapk1
|
UTSW |
13 |
60,866,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9301:Dapk1
|
UTSW |
13 |
60,866,125 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9407:Dapk1
|
UTSW |
13 |
60,898,991 (GRCm39) |
nonsense |
probably null |
|
|
R9491:Dapk1
|
UTSW |
13 |
60,877,369 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9624:Dapk1
|
UTSW |
13 |
60,895,937 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9726:Dapk1
|
UTSW |
13 |
60,898,948 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9794:Dapk1
|
UTSW |
13 |
60,909,082 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Dapk1
|
UTSW |
13 |
60,908,618 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTGGGATGCTAGAGCCCTTC -3'
(R):5'- ATGAACACTCTGGGGAGGAC -3'
Sequencing Primer
(F):5'- GATGCTAGAGCCCTTCCTGTCAG -3'
(R):5'- TTTCCTTGCCAAATGAAACACAGAG -3'
|
| Posted On |
2022-07-18 |
Incidental Mutation