Incidental Mutation 'R9516:Anapc1'
| ID |
718531 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Anapc1
|
| Ensembl Gene |
ENSMUSG00000014355 |
| Gene Name |
anaphase promoting complex subunit 1 |
| Synonyms |
Apc1, tsg24, Mcpr, 2610021O03Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9516 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
128452024-128529311 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 128517633 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Arginine
at position 337
(L337R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000014499
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014499]
[ENSMUST00000110333]
|
| AlphaFold |
P53995 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000014499
AA Change: L337R
PolyPhen 2
Score 0.766 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000014499
Gene: ENSMUSG00000014355
AA Change: L337R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ANAPC1
|
150 |
214 |
1.7e-13 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1415 |
N/A |
INTRINSIC |
|
Pfam:PC_rep
|
1467 |
1501 |
8.3e-8 |
PFAM |
|
low complexity region
|
1516 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1924 |
1936 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110333
AA Change: L337R
PolyPhen 2
Score 0.185 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000105962
Gene: ENSMUSG00000014355
AA Change: L337R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Apc1
|
149 |
227 |
1.7e-22 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3300002I08Rik |
T |
C |
2: 150,153,122 (GRCm39) |
N88D |
possibly damaging |
Het |
| 4933430I17Rik |
A |
G |
4: 62,460,916 (GRCm39) |
I264V |
probably benign |
Het |
| Abcc8 |
A |
G |
7: 45,787,429 (GRCm39) |
F591L |
probably benign |
Het |
| Abr |
G |
T |
11: 76,310,658 (GRCm39) |
T810K |
probably damaging |
Het |
| Abracl |
T |
C |
10: 17,894,631 (GRCm39) |
E6G |
unknown |
Het |
| Adamts3 |
A |
T |
5: 89,834,750 (GRCm39) |
Y871N |
probably damaging |
Het |
| Akap13 |
T |
C |
7: 75,354,275 (GRCm39) |
Y80H |
probably benign |
Het |
| Alas1 |
A |
G |
9: 106,115,840 (GRCm39) |
|
probably null |
Het |
| Apaf1 |
T |
C |
10: 90,915,816 (GRCm39) |
Y24C |
probably damaging |
Het |
| Arhgef16 |
A |
G |
4: 154,365,432 (GRCm39) |
V561A |
possibly damaging |
Het |
| Atp10b |
T |
A |
11: 43,121,224 (GRCm39) |
H962Q |
probably benign |
Het |
| Brsk2 |
A |
G |
7: 141,546,852 (GRCm39) |
T432A |
probably benign |
Het |
| C1rl |
T |
A |
6: 124,485,802 (GRCm39) |
V391E |
probably damaging |
Het |
| Caps2 |
A |
T |
10: 112,036,637 (GRCm39) |
H399L |
probably benign |
Het |
| Ccdc43 |
C |
A |
11: 102,577,207 (GRCm39) |
K199N |
probably benign |
Het |
| Ccdc7a |
G |
T |
8: 129,555,774 (GRCm39) |
P1198T |
unknown |
Het |
| Cct7 |
A |
G |
6: 85,444,625 (GRCm39) |
Y423C |
possibly damaging |
Het |
| Cep112 |
A |
G |
11: 108,648,514 (GRCm39) |
T783A |
probably damaging |
Het |
| Cep250 |
A |
G |
2: 155,833,459 (GRCm39) |
T1795A |
probably benign |
Het |
| Clasp1 |
T |
G |
1: 118,431,560 (GRCm39) |
S397A |
possibly damaging |
Het |
| Clock |
A |
C |
5: 76,377,227 (GRCm39) |
F691V |
possibly damaging |
Het |
| Cmklr1 |
A |
G |
5: 113,752,341 (GRCm39) |
V220A |
probably benign |
Het |
| Coro2b |
A |
T |
9: 62,335,291 (GRCm39) |
Y298* |
probably null |
Het |
| Cspg4b |
A |
T |
13: 113,455,649 (GRCm39) |
N565I |
|
Het |
| Cyp2t4 |
G |
A |
7: 26,854,717 (GRCm39) |
V66M |
possibly damaging |
Het |
| Dlk2 |
G |
A |
17: 46,613,432 (GRCm39) |
G186D |
probably damaging |
Het |
| Dok1 |
T |
C |
6: 83,009,972 (GRCm39) |
K46E |
probably damaging |
Het |
| Dok3 |
A |
G |
13: 55,672,186 (GRCm39) |
I164T |
probably benign |
Het |
| Ercc5 |
T |
A |
1: 44,207,041 (GRCm39) |
D651E |
probably damaging |
Het |
| Erp27 |
T |
C |
6: 136,885,066 (GRCm39) |
K244R |
probably benign |
Het |
| Fhip1a |
G |
A |
3: 85,580,559 (GRCm39) |
Q549* |
probably null |
Het |
| Flvcr2 |
T |
C |
12: 85,793,954 (GRCm39) |
V110A |
possibly damaging |
Het |
| Gsta3 |
T |
C |
1: 21,320,060 (GRCm39) |
L22P |
probably damaging |
Het |
| Hdac5 |
T |
C |
11: 102,093,522 (GRCm39) |
T493A |
probably benign |
Het |
| Hivep2 |
T |
A |
10: 14,005,523 (GRCm39) |
I707N |
probably benign |
Het |
| Hmox1 |
A |
G |
8: 75,823,544 (GRCm39) |
N71D |
probably benign |
Het |
| Hnrnpr |
G |
T |
4: 136,063,615 (GRCm39) |
V342F |
probably damaging |
Het |
| Ifi44 |
T |
C |
3: 151,438,108 (GRCm39) |
D393G |
probably damaging |
Het |
| Ighv1-82 |
A |
T |
12: 115,916,566 (GRCm39) |
F9I |
probably damaging |
Het |
| Kalrn |
A |
G |
16: 33,854,864 (GRCm39) |
S1999P |
probably damaging |
Het |
| Kcnq2 |
A |
G |
2: 180,776,753 (GRCm39) |
S45P |
probably benign |
Het |
| Krt77 |
A |
T |
15: 101,769,779 (GRCm39) |
Y364N |
probably damaging |
Het |
| Kti12 |
T |
C |
4: 108,705,476 (GRCm39) |
V130A |
probably benign |
Het |
| Lama2 |
T |
C |
10: 27,100,015 (GRCm39) |
E830G |
probably benign |
Het |
| Lrrn1 |
T |
A |
6: 107,545,505 (GRCm39) |
H434Q |
probably benign |
Het |
| Med13 |
A |
T |
11: 86,179,801 (GRCm39) |
N1382K |
probably benign |
Het |
| Mrpl42 |
A |
G |
10: 95,332,684 (GRCm39) |
|
probably null |
Het |
| Mtor |
A |
G |
4: 148,569,103 (GRCm39) |
D1140G |
probably benign |
Het |
| Mtrr |
A |
G |
13: 68,720,755 (GRCm39) |
I280T |
probably benign |
Het |
| Myh4 |
A |
T |
11: 67,139,290 (GRCm39) |
I536F |
probably damaging |
Het |
| Myh4 |
T |
A |
11: 67,141,129 (GRCm39) |
N730K |
probably damaging |
Het |
| Nat10 |
A |
C |
2: 103,563,364 (GRCm39) |
L545R |
probably damaging |
Het |
| Nav3 |
T |
A |
10: 109,520,015 (GRCm39) |
D2356V |
probably damaging |
Het |
| Nbea |
A |
T |
3: 55,937,366 (GRCm39) |
S748R |
probably damaging |
Het |
| Nlrp1a |
T |
C |
11: 70,998,488 (GRCm39) |
T904A |
probably benign |
Het |
| Nod2 |
A |
T |
8: 89,397,050 (GRCm39) |
N820I |
probably damaging |
Het |
| Nptx1 |
A |
G |
11: 119,433,381 (GRCm39) |
V406A |
probably damaging |
Het |
| Nrdc |
T |
A |
4: 108,901,863 (GRCm39) |
I644K |
probably benign |
Het |
| Or4e1 |
T |
C |
14: 52,700,873 (GRCm39) |
I198V |
probably benign |
Het |
| Ostf1 |
T |
A |
19: 18,573,735 (GRCm39) |
I38F |
probably benign |
Het |
| Pacc1 |
G |
A |
1: 191,082,004 (GRCm39) |
R337Q |
probably damaging |
Het |
| Pde4b |
G |
T |
4: 102,462,183 (GRCm39) |
D605Y |
probably damaging |
Het |
| Pde4d |
A |
G |
13: 109,397,196 (GRCm39) |
T3A |
|
Het |
| Pknox1 |
A |
G |
17: 31,822,183 (GRCm39) |
I317V |
probably damaging |
Het |
| Plekhh2 |
A |
G |
17: 84,918,240 (GRCm39) |
N1283S |
probably benign |
Het |
| Ppp3cb |
G |
A |
14: 20,573,868 (GRCm39) |
A289V |
probably damaging |
Het |
| Prag1 |
A |
G |
8: 36,607,208 (GRCm39) |
D983G |
probably damaging |
Het |
| Psmd13 |
C |
T |
7: 140,478,455 (GRCm39) |
T62M |
|
Het |
| Rab42 |
C |
T |
4: 132,029,890 (GRCm39) |
V111I |
|
Het |
| Rabl2 |
T |
A |
15: 89,474,631 (GRCm39) |
|
probably null |
Het |
| Rapgef6 |
T |
A |
11: 54,582,169 (GRCm39) |
S1365R |
probably damaging |
Het |
| Rassf4 |
G |
T |
6: 116,617,265 (GRCm39) |
H247N |
possibly damaging |
Het |
| Rbfox1 |
A |
G |
16: 7,227,573 (GRCm39) |
T363A |
probably benign |
Het |
| Rbmyf9 |
T |
A |
Y: 3,774,888 (GRCm39) |
F28L |
probably damaging |
Het |
| Sbf1 |
T |
C |
15: 89,184,742 (GRCm39) |
D1091G |
probably damaging |
Het |
| Scaper |
A |
G |
9: 55,593,275 (GRCm39) |
V454A |
probably benign |
Het |
| Selenbp2 |
G |
A |
3: 94,607,352 (GRCm39) |
D258N |
probably benign |
Het |
| Sirpa |
A |
T |
2: 129,457,555 (GRCm39) |
I210F |
probably damaging |
Het |
| Skint4 |
T |
C |
4: 112,015,236 (GRCm39) |
S434P |
probably benign |
Het |
| Slc26a5 |
G |
A |
5: 22,016,337 (GRCm39) |
Q682* |
probably null |
Het |
| Slco4a1 |
C |
T |
2: 180,115,943 (GRCm39) |
S693F |
possibly damaging |
Het |
| Smpd3 |
A |
G |
8: 106,992,119 (GRCm39) |
F145L |
probably benign |
Het |
| Son |
CATGGACTCCCAGATGTTAGCAACTAGCTCTATGGACTCCCAGATGTTAGCAACTAGCTCTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCTCCATGGACTCCCAGATGTTAGCAAC |
CATGGACTCCCAGATGTTAGCAACTAGCTCTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCTCCATGGACTCCCAGATGTTAGCAAC |
16: 91,453,579 (GRCm39) |
|
probably benign |
Het |
| Spata31d1c |
A |
T |
13: 65,184,040 (GRCm39) |
L527F |
probably damaging |
Het |
| Srd5a3 |
A |
G |
5: 76,297,794 (GRCm39) |
N199D |
probably benign |
Het |
| Stard9 |
C |
G |
2: 120,534,564 (GRCm39) |
P3607R |
probably damaging |
Het |
| Sytl1 |
A |
G |
4: 132,986,291 (GRCm39) |
|
probably null |
Het |
| Tas2r126 |
A |
G |
6: 42,412,307 (GRCm39) |
H280R |
probably null |
Het |
| Tcf4 |
C |
T |
18: 69,652,944 (GRCm39) |
|
probably benign |
Het |
| Tlcd2 |
A |
G |
11: 75,359,112 (GRCm39) |
T28A |
probably damaging |
Het |
| Tm7sf3 |
C |
T |
6: 146,525,179 (GRCm39) |
D89N |
possibly damaging |
Het |
| Tmem119 |
A |
G |
5: 113,933,267 (GRCm39) |
L178P |
probably damaging |
Het |
| Tmprss7 |
T |
C |
16: 45,484,564 (GRCm39) |
D532G |
probably benign |
Het |
| Tnfaip8l3 |
A |
G |
9: 53,934,777 (GRCm39) |
I66T |
probably benign |
Het |
| Tor1b |
A |
G |
2: 30,843,185 (GRCm39) |
Y50C |
probably damaging |
Het |
| Tpp2 |
T |
A |
1: 44,017,648 (GRCm39) |
S751T |
probably benign |
Het |
| Tpra1 |
T |
C |
6: 88,887,221 (GRCm39) |
V193A |
probably benign |
Het |
| Trip12 |
A |
T |
1: 84,735,215 (GRCm39) |
V932E |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,777,104 (GRCm39) |
T1479S |
unknown |
Het |
| Unc13c |
A |
T |
9: 73,392,220 (GRCm39) |
V2044D |
probably damaging |
Het |
| Usp25 |
T |
G |
16: 76,852,076 (GRCm39) |
V197G |
probably damaging |
Het |
| Vmn2r34 |
A |
G |
7: 7,675,366 (GRCm39) |
V674A |
probably benign |
Het |
| Zfp7 |
T |
C |
15: 76,775,484 (GRCm39) |
S509P |
probably damaging |
Het |
| Zfp821 |
A |
G |
8: 110,447,856 (GRCm39) |
T66A |
probably damaging |
Het |
| Zfp97 |
T |
A |
17: 17,365,930 (GRCm39) |
N476K |
possibly damaging |
Het |
|
| Other mutations in Anapc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Anapc1
|
APN |
2 |
128,487,050 (GRCm39) |
splice site |
probably benign |
|
|
IGL00704:Anapc1
|
APN |
2 |
128,505,904 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL01023:Anapc1
|
APN |
2 |
128,471,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01432:Anapc1
|
APN |
2 |
128,475,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Anapc1
|
APN |
2 |
128,495,090 (GRCm39) |
missense |
probably benign |
|
|
IGL02089:Anapc1
|
APN |
2 |
128,505,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02275:Anapc1
|
APN |
2 |
128,501,772 (GRCm39) |
missense |
probably benign |
|
|
IGL02570:Anapc1
|
APN |
2 |
128,487,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02597:Anapc1
|
APN |
2 |
128,465,851 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02726:Anapc1
|
APN |
2 |
128,501,705 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03265:Anapc1
|
APN |
2 |
128,469,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03304:Anapc1
|
APN |
2 |
128,469,033 (GRCm39) |
splice site |
probably benign |
|
|
IGL03327:Anapc1
|
APN |
2 |
128,465,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0023:Anapc1
|
UTSW |
2 |
128,520,138 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0084:Anapc1
|
UTSW |
2 |
128,465,886 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0255:Anapc1
|
UTSW |
2 |
128,476,631 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0377:Anapc1
|
UTSW |
2 |
128,483,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0467:Anapc1
|
UTSW |
2 |
128,510,963 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0514:Anapc1
|
UTSW |
2 |
128,474,575 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0591:Anapc1
|
UTSW |
2 |
128,461,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0919:Anapc1
|
UTSW |
2 |
128,459,651 (GRCm39) |
missense |
probably benign |
|
|
R1175:Anapc1
|
UTSW |
2 |
128,522,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Anapc1
|
UTSW |
2 |
128,459,617 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1547:Anapc1
|
UTSW |
2 |
128,459,476 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1556:Anapc1
|
UTSW |
2 |
128,466,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1567:Anapc1
|
UTSW |
2 |
128,459,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Anapc1
|
UTSW |
2 |
128,470,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1645:Anapc1
|
UTSW |
2 |
128,500,166 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1677:Anapc1
|
UTSW |
2 |
128,518,128 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1854:Anapc1
|
UTSW |
2 |
128,517,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1856:Anapc1
|
UTSW |
2 |
128,501,708 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1959:Anapc1
|
UTSW |
2 |
128,475,335 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1984:Anapc1
|
UTSW |
2 |
128,511,608 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2034:Anapc1
|
UTSW |
2 |
128,490,378 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2283:Anapc1
|
UTSW |
2 |
128,484,468 (GRCm39) |
missense |
probably benign |
0.23 |
|
R2928:Anapc1
|
UTSW |
2 |
128,522,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Anapc1
|
UTSW |
2 |
128,484,602 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R3904:Anapc1
|
UTSW |
2 |
128,484,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Anapc1
|
UTSW |
2 |
128,469,149 (GRCm39) |
intron |
probably benign |
|
|
R4359:Anapc1
|
UTSW |
2 |
128,465,476 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4392:Anapc1
|
UTSW |
2 |
128,518,169 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4574:Anapc1
|
UTSW |
2 |
128,469,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4682:Anapc1
|
UTSW |
2 |
128,505,925 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4770:Anapc1
|
UTSW |
2 |
128,527,980 (GRCm39) |
splice site |
probably benign |
|
|
R4824:Anapc1
|
UTSW |
2 |
128,470,610 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4960:Anapc1
|
UTSW |
2 |
128,526,514 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5016:Anapc1
|
UTSW |
2 |
128,449,095 (GRCm39) |
unclassified |
probably benign |
|
|
R5063:Anapc1
|
UTSW |
2 |
128,471,469 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R5128:Anapc1
|
UTSW |
2 |
128,501,837 (GRCm39) |
missense |
probably benign |
|
|
R5271:Anapc1
|
UTSW |
2 |
128,527,905 (GRCm39) |
nonsense |
probably null |
|
|
R5363:Anapc1
|
UTSW |
2 |
128,492,114 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5469:Anapc1
|
UTSW |
2 |
128,517,621 (GRCm39) |
nonsense |
probably null |
|
|
R5473:Anapc1
|
UTSW |
2 |
128,449,115 (GRCm39) |
unclassified |
probably benign |
|
|
R5559:Anapc1
|
UTSW |
2 |
128,522,354 (GRCm39) |
nonsense |
probably null |
|
|
R5631:Anapc1
|
UTSW |
2 |
128,499,137 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5747:Anapc1
|
UTSW |
2 |
128,466,836 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5840:Anapc1
|
UTSW |
2 |
128,448,957 (GRCm39) |
unclassified |
probably benign |
|
|
R6226:Anapc1
|
UTSW |
2 |
128,492,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6526:Anapc1
|
UTSW |
2 |
128,514,055 (GRCm39) |
nonsense |
probably null |
|
|
R6561:Anapc1
|
UTSW |
2 |
128,505,919 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6743:Anapc1
|
UTSW |
2 |
128,526,454 (GRCm39) |
nonsense |
probably null |
|
|
R6799:Anapc1
|
UTSW |
2 |
128,501,657 (GRCm39) |
missense |
probably null |
0.38 |
|
R6887:Anapc1
|
UTSW |
2 |
128,501,688 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6978:Anapc1
|
UTSW |
2 |
128,511,820 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7011:Anapc1
|
UTSW |
2 |
128,490,601 (GRCm39) |
splice site |
probably null |
|
|
R7041:Anapc1
|
UTSW |
2 |
128,470,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7047:Anapc1
|
UTSW |
2 |
128,457,350 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7074:Anapc1
|
UTSW |
2 |
128,520,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Anapc1
|
UTSW |
2 |
128,516,522 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7123:Anapc1
|
UTSW |
2 |
128,454,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7309:Anapc1
|
UTSW |
2 |
128,516,604 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7693:Anapc1
|
UTSW |
2 |
128,483,457 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7839:Anapc1
|
UTSW |
2 |
128,526,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7847:Anapc1
|
UTSW |
2 |
128,511,828 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7960:Anapc1
|
UTSW |
2 |
128,516,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Anapc1
|
UTSW |
2 |
128,490,408 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8127:Anapc1
|
UTSW |
2 |
128,474,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8228:Anapc1
|
UTSW |
2 |
128,461,837 (GRCm39) |
nonsense |
probably null |
|
|
R8402:Anapc1
|
UTSW |
2 |
128,472,148 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8422:Anapc1
|
UTSW |
2 |
128,517,757 (GRCm39) |
missense |
probably benign |
|
|
R8425:Anapc1
|
UTSW |
2 |
128,511,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8469:Anapc1
|
UTSW |
2 |
128,500,264 (GRCm39) |
splice site |
probably null |
|
|
R8553:Anapc1
|
UTSW |
2 |
128,461,833 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8688:Anapc1
|
UTSW |
2 |
128,527,748 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8699:Anapc1
|
UTSW |
2 |
128,483,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8719:Anapc1
|
UTSW |
2 |
128,483,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8775:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8775-TAIL:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8806:Anapc1
|
UTSW |
2 |
128,464,333 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8973:Anapc1
|
UTSW |
2 |
128,505,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8977:Anapc1
|
UTSW |
2 |
128,483,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9000:Anapc1
|
UTSW |
2 |
128,476,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9080:Anapc1
|
UTSW |
2 |
128,464,426 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9203:Anapc1
|
UTSW |
2 |
128,465,422 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9314:Anapc1
|
UTSW |
2 |
128,464,420 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9386:Anapc1
|
UTSW |
2 |
128,459,642 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9415:Anapc1
|
UTSW |
2 |
128,476,598 (GRCm39) |
missense |
probably benign |
|
|
R9436:Anapc1
|
UTSW |
2 |
128,518,045 (GRCm39) |
missense |
probably benign |
|
|
R9563:Anapc1
|
UTSW |
2 |
128,505,980 (GRCm39) |
nonsense |
probably null |
|
|
R9572:Anapc1
|
UTSW |
2 |
128,505,976 (GRCm39) |
missense |
probably benign |
|
|
R9757:Anapc1
|
UTSW |
2 |
128,517,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9766:Anapc1
|
UTSW |
2 |
128,500,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Anapc1
|
UTSW |
2 |
128,516,621 (GRCm39) |
missense |
probably benign |
0.10 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATACTGGAAACTGAGGCATCATG -3'
(R):5'- TGCTGTTTTAAAGTTCCCTGAGC -3'
Sequencing Primer
(F):5'- CTGAGGCATCATGAATTCACAAGTC -3'
(R):5'- CTGAGCAGGCAGGGACC -3'
|
| Posted On |
2022-07-18 |
Incidental Mutation