Incidental Mutation 'R9147:Tnrc6a'
| ID |
720387 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnrc6a
|
| Ensembl Gene |
ENSMUSG00000052707 |
| Gene Name |
trinucleotide repeat containing 6a |
| Synonyms |
3110054G10Rik, 2010321I05Rik, Tnrc6, CAGH26, D130023A07Rik |
| MMRRC Submission |
068936-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.850)
|
| Stock # |
R9147 (G1)
|
| Quality Score |
185.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
122723108-122794519 bp(+) (GRCm39) |
| Type of Mutation |
intron |
| DNA Base Change (assembly) |
T to G
at 122785667 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094053]
[ENSMUST00000205514]
|
| AlphaFold |
Q3UHK8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094053
|
| SMART Domains |
Protein: ENSMUSP00000091595
Gene: ENSMUSG00000052707
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
69 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
281 |
294 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
568 |
590 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
690 |
853 |
3.51e-6 |
PROSPERO |
|
low complexity region
|
858 |
871 |
N/A |
INTRINSIC |
|
Pfam:Ago_hook
|
1028 |
1190 |
1.2e-29 |
PFAM |
|
low complexity region
|
1284 |
1296 |
N/A |
INTRINSIC |
|
low complexity region
|
1301 |
1316 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1376 |
N/A |
INTRINSIC |
|
low complexity region
|
1386 |
1392 |
N/A |
INTRINSIC |
|
Pfam:TNRC6-PABC_bdg
|
1439 |
1714 |
1.5e-126 |
PFAM |
|
RRM
|
1717 |
1784 |
4.95e-2 |
SMART |
|
low complexity region
|
1808 |
1820 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000205514
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000205760
|
| Meta Mutation Damage Score |
0.0846 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
97% (93/96) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein is highly similar to a human protein that functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The human protein associates with messenger RNAs and argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies, and inhibiting its expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit partial embryonic lethality during organogenesis associated with impaired hematopoiesis. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(21) : Gene trapped(21) |
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110032F04Rik |
T |
A |
3: 68,777,345 (GRCm39) |
I102N |
probably damaging |
Het |
| 2610008E11Rik |
A |
T |
10: 78,903,406 (GRCm39) |
C303* |
probably null |
Het |
| A430033K04Rik |
T |
A |
5: 138,644,547 (GRCm39) |
V144D |
possibly damaging |
Het |
| Adamts13 |
T |
A |
2: 26,883,024 (GRCm39) |
M858K |
probably benign |
Het |
| Ankrd29 |
T |
C |
18: 12,408,760 (GRCm39) |
|
probably benign |
Het |
| Apc |
T |
A |
18: 34,450,710 (GRCm39) |
S2535R |
probably damaging |
Het |
| C1s1 |
T |
C |
6: 124,517,758 (GRCm39) |
D74G |
probably damaging |
Het |
| Cacnb2 |
G |
A |
2: 14,972,773 (GRCm39) |
G227S |
possibly damaging |
Het |
| Cbs |
T |
C |
17: 31,844,889 (GRCm39) |
D137G |
probably damaging |
Het |
| Ccdc136 |
A |
G |
6: 29,418,070 (GRCm39) |
E846G |
probably damaging |
Het |
| Cd6 |
A |
T |
19: 10,776,855 (GRCm39) |
S57T |
probably benign |
Het |
| Col11a2 |
T |
A |
17: 34,273,119 (GRCm39) |
|
probably benign |
Het |
| Ctsj |
T |
C |
13: 61,149,249 (GRCm39) |
Y264C |
probably damaging |
Het |
| Dennd3 |
T |
A |
15: 73,429,463 (GRCm39) |
N915K |
probably damaging |
Het |
| Dst |
T |
C |
1: 34,228,149 (GRCm39) |
L1914P |
probably damaging |
Het |
| E2f2 |
A |
T |
4: 135,908,595 (GRCm39) |
|
probably null |
Het |
| Edc4 |
T |
C |
8: 106,612,478 (GRCm39) |
L172P |
probably damaging |
Het |
| Epb41l5 |
A |
T |
1: 119,570,319 (GRCm39) |
L23H |
probably damaging |
Het |
| Fbxo2 |
A |
G |
4: 148,250,166 (GRCm39) |
E232G |
probably damaging |
Het |
| Fmn1 |
A |
C |
2: 113,271,973 (GRCm39) |
N114H |
unknown |
Het |
| Foxj1 |
T |
G |
11: 116,225,236 (GRCm39) |
I44L |
probably damaging |
Het |
| Foxp1 |
TTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGTTGCTGCTGCTGTTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGCTGCTGCTG |
TTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGTTGCTGCTGCTGTTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGCTGCTGCTG |
6: 99,052,866 (GRCm39) |
|
probably benign |
Het |
| Foxp2 |
A |
T |
6: 15,286,711 (GRCm39) |
Q67L |
possibly damaging |
Het |
| Fuz |
C |
T |
7: 44,549,710 (GRCm39) |
P396L |
probably damaging |
Het |
| Galntl5 |
A |
T |
5: 25,415,353 (GRCm39) |
I295L |
possibly damaging |
Het |
| Gjd4 |
T |
A |
18: 9,280,095 (GRCm39) |
T328S |
probably benign |
Het |
| Gramd1a |
A |
T |
7: 30,837,606 (GRCm39) |
|
probably benign |
Het |
| Gzmb |
T |
C |
14: 56,496,964 (GRCm39) |
Y219C |
possibly damaging |
Het |
| Hs3st5 |
A |
T |
10: 36,708,917 (GRCm39) |
I151F |
probably damaging |
Het |
| Hspa12a |
T |
G |
19: 58,793,890 (GRCm39) |
T324P |
probably damaging |
Het |
| Ighv4-1 |
A |
T |
12: 113,912,000 (GRCm39) |
D84E |
possibly damaging |
Het |
| Il31ra |
C |
T |
13: 112,670,276 (GRCm39) |
E371K |
probably benign |
Het |
| Imp4 |
G |
T |
1: 34,482,473 (GRCm39) |
V71L |
probably benign |
Het |
| Itgax |
A |
G |
7: 127,747,913 (GRCm39) |
T1068A |
possibly damaging |
Het |
| Klhl24 |
C |
T |
16: 19,936,690 (GRCm39) |
R433C |
probably damaging |
Het |
| Larp4b |
C |
A |
13: 9,186,819 (GRCm39) |
P49Q |
possibly damaging |
Het |
| Macc1 |
T |
C |
12: 119,414,091 (GRCm39) |
S756P |
possibly damaging |
Het |
| Mael |
A |
G |
1: 166,029,259 (GRCm39) |
V388A |
probably benign |
Het |
| Megf6 |
A |
G |
4: 154,339,130 (GRCm39) |
T556A |
probably benign |
Het |
| Mettl6 |
T |
C |
14: 31,204,855 (GRCm39) |
D189G |
probably damaging |
Het |
| Moxd2 |
C |
A |
6: 40,860,978 (GRCm39) |
C271F |
probably damaging |
Het |
| Ncor1 |
A |
T |
11: 62,224,672 (GRCm39) |
Y863N |
probably damaging |
Het |
| Ndst4 |
C |
T |
3: 125,231,722 (GRCm39) |
A97V |
probably damaging |
Het |
| Nherf4 |
A |
G |
9: 44,160,676 (GRCm39) |
C240R |
probably damaging |
Het |
| Nos1 |
G |
C |
5: 118,017,402 (GRCm39) |
R255P |
probably benign |
Het |
| Nup160 |
A |
G |
2: 90,533,489 (GRCm39) |
D646G |
probably damaging |
Het |
| Nxt2 |
C |
T |
X: 141,020,747 (GRCm39) |
A118V |
possibly damaging |
Het |
| Or1j19 |
A |
G |
2: 36,676,938 (GRCm39) |
T134A |
probably benign |
Het |
| Or1p1 |
A |
C |
11: 74,180,169 (GRCm39) |
Q232H |
probably damaging |
Het |
| Or5c1 |
T |
C |
2: 37,222,017 (GRCm39) |
L86P |
possibly damaging |
Het |
| Or7h8 |
T |
A |
9: 20,124,358 (GRCm39) |
F238I |
probably damaging |
Het |
| Or8k24 |
A |
G |
2: 86,216,324 (GRCm39) |
V146A |
probably benign |
Het |
| Pabpc6 |
C |
T |
17: 9,886,937 (GRCm39) |
S538N |
probably benign |
Het |
| Pcdhga1 |
C |
A |
18: 37,796,433 (GRCm39) |
A479D |
possibly damaging |
Het |
| Pdgfd |
A |
T |
9: 6,333,328 (GRCm39) |
D172V |
probably benign |
Het |
| Pfpl |
A |
T |
19: 12,405,804 (GRCm39) |
E18D |
possibly damaging |
Het |
| Pih1d2 |
T |
A |
9: 50,532,321 (GRCm39) |
D126E |
possibly damaging |
Het |
| Ppp1r13b |
T |
C |
12: 111,800,268 (GRCm39) |
H626R |
probably benign |
Het |
| Ppp6r3 |
A |
T |
19: 3,543,974 (GRCm39) |
V347D |
probably damaging |
Het |
| Ptpra |
T |
A |
2: 30,328,255 (GRCm39) |
M192K |
probably damaging |
Het |
| Ptpra |
G |
T |
2: 30,328,256 (GRCm39) |
M192I |
probably benign |
Het |
| Ptprj |
G |
A |
2: 90,288,562 (GRCm39) |
S801L |
probably benign |
Het |
| Rasd2 |
C |
T |
8: 75,948,847 (GRCm39) |
R258* |
probably null |
Het |
| Rfx3 |
A |
T |
19: 27,878,207 (GRCm39) |
V30E |
possibly damaging |
Het |
| Rgs2 |
A |
G |
1: 143,877,925 (GRCm39) |
S124P |
probably damaging |
Het |
| Ros1 |
A |
G |
10: 51,927,039 (GRCm39) |
F2215L |
probably benign |
Het |
| Rph3a |
T |
C |
5: 121,086,880 (GRCm39) |
N440S |
possibly damaging |
Het |
| Sacs |
T |
C |
14: 61,450,137 (GRCm39) |
V4061A |
possibly damaging |
Het |
| Scgb1b3 |
G |
A |
7: 31,075,051 (GRCm39) |
V7M |
unknown |
Het |
| Scn7a |
T |
C |
2: 66,514,507 (GRCm39) |
D1089G |
possibly damaging |
Het |
| Sdk2 |
C |
T |
11: 113,714,226 (GRCm39) |
R1582Q |
probably benign |
Het |
| Sdr16c5 |
T |
C |
4: 3,996,200 (GRCm39) |
M298V |
probably benign |
Het |
| Sebox |
A |
G |
11: 78,395,222 (GRCm39) |
D188G |
possibly damaging |
Het |
| Serpinf2 |
A |
T |
11: 75,323,418 (GRCm39) |
F429L |
probably damaging |
Het |
| Six4 |
A |
C |
12: 73,155,681 (GRCm39) |
S429A |
probably benign |
Het |
| Slc2a10 |
A |
T |
2: 165,357,543 (GRCm39) |
H401L |
possibly damaging |
Het |
| Ssbp2 |
T |
C |
13: 91,842,141 (GRCm39) |
S321P |
probably damaging |
Het |
| Syne2 |
A |
G |
12: 75,937,158 (GRCm39) |
E252G |
probably damaging |
Het |
| Synj2 |
T |
C |
17: 6,084,172 (GRCm39) |
I1178T |
probably damaging |
Het |
| Tafa5 |
T |
C |
15: 87,428,775 (GRCm39) |
I28T |
probably benign |
Het |
| Tbc1d10a |
G |
T |
11: 4,136,835 (GRCm39) |
R16L |
unknown |
Het |
| Tmem132b |
C |
A |
5: 125,864,167 (GRCm39) |
Q758K |
probably damaging |
Het |
| Tril |
A |
G |
6: 53,795,137 (GRCm39) |
L695P |
probably damaging |
Het |
| Tspan3 |
A |
T |
9: 56,043,960 (GRCm39) |
Y243* |
probably null |
Het |
| Ufl1 |
A |
T |
4: 25,278,712 (GRCm39) |
|
probably benign |
Het |
| Utp4 |
A |
T |
8: 107,621,310 (GRCm39) |
N29I |
possibly damaging |
Het |
| Vmn1r176 |
C |
T |
7: 23,534,785 (GRCm39) |
G123S |
probably benign |
Het |
| Vmn1r225 |
T |
A |
17: 20,722,577 (GRCm39) |
M6K |
possibly damaging |
Het |
| Vmn1r229 |
T |
C |
17: 21,034,758 (GRCm39) |
M1T |
probably null |
Het |
| Vmn2r80 |
A |
T |
10: 79,030,687 (GRCm39) |
I838F |
probably damaging |
Het |
| Vmn2r98 |
T |
A |
17: 19,286,383 (GRCm39) |
W294R |
probably benign |
Het |
| Wnk1 |
A |
G |
6: 119,925,631 (GRCm39) |
S1527P |
unknown |
Het |
| Zdhhc17 |
A |
T |
10: 110,785,503 (GRCm39) |
S436R |
possibly damaging |
Het |
| Zfp12 |
T |
C |
5: 143,230,389 (GRCm39) |
S271P |
probably damaging |
Het |
| Zfp330 |
T |
C |
8: 83,491,063 (GRCm39) |
Y249C |
|
Het |
| Zfp444 |
A |
G |
7: 6,192,678 (GRCm39) |
H232R |
probably damaging |
Het |
|
| Other mutations in Tnrc6a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00335:Tnrc6a
|
APN |
7 |
122,770,003 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL00580:Tnrc6a
|
APN |
7 |
122,773,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01309:Tnrc6a
|
APN |
7 |
122,770,717 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02004:Tnrc6a
|
APN |
7 |
122,780,589 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL02142:Tnrc6a
|
APN |
7 |
122,751,414 (GRCm39) |
intron |
probably benign |
|
|
IGL02220:Tnrc6a
|
APN |
7 |
122,769,679 (GRCm39) |
missense |
probably benign |
|
|
IGL02436:Tnrc6a
|
APN |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
IGL02670:Tnrc6a
|
APN |
7 |
122,770,535 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02743:Tnrc6a
|
APN |
7 |
122,770,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
0152:Tnrc6a
|
UTSW |
7 |
122,779,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0369:Tnrc6a
|
UTSW |
7 |
122,770,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0512:Tnrc6a
|
UTSW |
7 |
122,785,951 (GRCm39) |
splice site |
probably benign |
|
|
R0566:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0600:Tnrc6a
|
UTSW |
7 |
122,771,039 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0751:Tnrc6a
|
UTSW |
7 |
122,769,563 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1184:Tnrc6a
|
UTSW |
7 |
122,769,563 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1319:Tnrc6a
|
UTSW |
7 |
122,783,474 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1585:Tnrc6a
|
UTSW |
7 |
122,776,098 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1709:Tnrc6a
|
UTSW |
7 |
122,769,205 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1776:Tnrc6a
|
UTSW |
7 |
122,770,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Tnrc6a
|
UTSW |
7 |
122,792,140 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1807:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R1876:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2010:Tnrc6a
|
UTSW |
7 |
122,770,269 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2086:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2089:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2511:Tnrc6a
|
UTSW |
7 |
122,770,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2830:Tnrc6a
|
UTSW |
7 |
122,792,172 (GRCm39) |
makesense |
probably null |
|
|
R2850:Tnrc6a
|
UTSW |
7 |
122,779,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3916:Tnrc6a
|
UTSW |
7 |
122,780,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4028:Tnrc6a
|
UTSW |
7 |
122,769,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4235:Tnrc6a
|
UTSW |
7 |
122,770,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4439:Tnrc6a
|
UTSW |
7 |
122,751,405 (GRCm39) |
nonsense |
probably null |
|
|
R4525:Tnrc6a
|
UTSW |
7 |
122,779,005 (GRCm39) |
missense |
probably benign |
|
|
R4578:Tnrc6a
|
UTSW |
7 |
122,783,444 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4613:Tnrc6a
|
UTSW |
7 |
122,783,512 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4711:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4722:Tnrc6a
|
UTSW |
7 |
122,791,313 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4746:Tnrc6a
|
UTSW |
7 |
122,789,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4892:Tnrc6a
|
UTSW |
7 |
122,769,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Tnrc6a
|
UTSW |
7 |
122,791,836 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4967:Tnrc6a
|
UTSW |
7 |
122,789,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5064:Tnrc6a
|
UTSW |
7 |
122,785,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5239:Tnrc6a
|
UTSW |
7 |
122,785,842 (GRCm39) |
missense |
probably benign |
|
|
R5604:Tnrc6a
|
UTSW |
7 |
122,773,459 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5805:Tnrc6a
|
UTSW |
7 |
122,769,299 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5942:Tnrc6a
|
UTSW |
7 |
122,785,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Tnrc6a
|
UTSW |
7 |
122,781,603 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6212:Tnrc6a
|
UTSW |
7 |
122,742,965 (GRCm39) |
splice site |
probably null |
|
|
R6284:Tnrc6a
|
UTSW |
7 |
122,770,558 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6417:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6420:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6575:Tnrc6a
|
UTSW |
7 |
122,769,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6760:Tnrc6a
|
UTSW |
7 |
122,771,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6886:Tnrc6a
|
UTSW |
7 |
122,786,668 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6968:Tnrc6a
|
UTSW |
7 |
122,781,650 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7216:Tnrc6a
|
UTSW |
7 |
122,770,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7260:Tnrc6a
|
UTSW |
7 |
122,785,813 (GRCm39) |
missense |
probably benign |
0.36 |
|
R7299:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
|
|
R7322:Tnrc6a
|
UTSW |
7 |
122,770,731 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7500:Tnrc6a
|
UTSW |
7 |
122,772,673 (GRCm39) |
splice site |
probably null |
|
|
R7872:Tnrc6a
|
UTSW |
7 |
122,779,057 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8270:Tnrc6a
|
UTSW |
7 |
122,769,294 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8313:Tnrc6a
|
UTSW |
7 |
122,769,936 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8348:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8390:Tnrc6a
|
UTSW |
7 |
122,761,794 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8448:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8514:Tnrc6a
|
UTSW |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
R8552:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R8767:Tnrc6a
|
UTSW |
7 |
122,783,133 (GRCm39) |
unclassified |
probably benign |
|
|
R9047:Tnrc6a
|
UTSW |
7 |
122,778,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9153:Tnrc6a
|
UTSW |
7 |
122,773,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9166:Tnrc6a
|
UTSW |
7 |
122,786,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9179:Tnrc6a
|
UTSW |
7 |
122,791,881 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9192:Tnrc6a
|
UTSW |
7 |
122,789,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Tnrc6a
|
UTSW |
7 |
122,778,958 (GRCm39) |
missense |
probably benign |
0.24 |
|
R9778:Tnrc6a
|
UTSW |
7 |
122,769,635 (GRCm39) |
missense |
probably benign |
0.43 |
|
X0064:Tnrc6a
|
UTSW |
7 |
122,769,021 (GRCm39) |
missense |
probably benign |
0.28 |
|
Z1176:Tnrc6a
|
UTSW |
7 |
122,761,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTGGCACTTGAGCAAAGGG -3'
(R):5'- TATTGAACCTGGAGGACTGGCTG -3'
Sequencing Primer
(F):5'- AGCAAAGGGTCTGTCTTCATCAG -3'
(R):5'- ACTGGCTGGTGAAGTACTGC -3'
|
| Posted On |
2022-08-03 |
Incidental Mutation