Incidental Mutation 'R9563:Rictor'
| ID |
721275 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rictor
|
| Ensembl Gene |
ENSMUSG00000050310 |
| Gene Name |
RPTOR independent companion of MTOR, complex 2 |
| Synonyms |
D530039E11Rik, 4921505C17Rik, 6030405M08Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9563 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
15 |
| Chromosomal Location |
6737860-6829882 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 6797562 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Isoleucine
at position 306
(N306I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000051809
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000061656]
|
| AlphaFold |
Q6QI06 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000061656
AA Change: N306I
PolyPhen 2
Score 0.826 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000051809
Gene: ENSMUSG00000050310
AA Change: N306I
| Domain | Start | End | E-Value | Type |
|---|
|
RICTOR_N
|
57 |
439 |
4.02e-185 |
SMART |
|
RICTOR_M
|
523 |
742 |
5.66e-98 |
SMART |
|
RasGEF_N_2
|
743 |
857 |
1.26e-54 |
SMART |
|
RICTOR_V
|
920 |
992 |
1.44e-40 |
SMART |
|
low complexity region
|
1019 |
1043 |
N/A |
INTRINSIC |
|
RICTOR_phospho
|
1084 |
1189 |
4.06e-58 |
SMART |
|
low complexity region
|
1221 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1255 |
1266 |
N/A |
INTRINSIC |
|
low complexity region
|
1273 |
1287 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1414 |
N/A |
INTRINSIC |
|
low complexity region
|
1464 |
1474 |
N/A |
INTRINSIC |
|
low complexity region
|
1616 |
1628 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality during organogenesis associated with abnormal placental morphology. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 127 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2m |
T |
A |
6: 121,645,009 (GRCm39) |
D953E |
probably damaging |
Het |
| Acod1 |
A |
C |
14: 103,287,109 (GRCm39) |
Y80S |
probably damaging |
Het |
| Actr5 |
A |
G |
2: 158,470,135 (GRCm39) |
D255G |
probably damaging |
Het |
| Akna |
A |
G |
4: 63,312,944 (GRCm39) |
V393A |
probably damaging |
Het |
| Amotl1 |
T |
C |
9: 14,473,513 (GRCm39) |
K562R |
possibly damaging |
Het |
| Amz1 |
T |
A |
5: 140,738,133 (GRCm39) |
D464E |
probably damaging |
Het |
| Anapc1 |
G |
A |
2: 128,505,980 (GRCm39) |
Q619* |
probably null |
Het |
| Arfgef3 |
C |
T |
10: 18,522,275 (GRCm39) |
G584R |
probably damaging |
Het |
| Armt1 |
AC |
A |
10: 4,400,848 (GRCm39) |
|
probably null |
Het |
| Atr |
G |
C |
9: 95,802,833 (GRCm39) |
V1832L |
probably damaging |
Het |
| Bsn |
T |
C |
9: 107,984,616 (GRCm39) |
D374G |
|
Het |
| Cap1 |
A |
G |
4: 122,758,505 (GRCm39) |
V225A |
probably benign |
Het |
| Cc2d1a |
A |
G |
8: 84,863,758 (GRCm39) |
S562P |
probably benign |
Het |
| Ccdc30 |
T |
C |
4: 119,250,821 (GRCm39) |
N141S |
possibly damaging |
Het |
| Cdc42bpb |
A |
G |
12: 111,265,762 (GRCm39) |
V1390A |
possibly damaging |
Het |
| Cdc42ep1 |
A |
T |
15: 78,733,782 (GRCm39) |
H294L |
probably benign |
Het |
| Col6a6 |
C |
A |
9: 105,572,952 (GRCm39) |
G2185C |
probably benign |
Het |
| Col7a1 |
T |
C |
9: 108,791,809 (GRCm39) |
V1232A |
unknown |
Het |
| Copb1 |
A |
G |
7: 113,836,034 (GRCm39) |
I449T |
possibly damaging |
Het |
| Cplane1 |
T |
G |
15: 8,216,563 (GRCm39) |
L594V |
probably benign |
Het |
| Ctdsp2 |
A |
G |
10: 126,832,040 (GRCm39) |
D216G |
probably damaging |
Het |
| Cttnbp2 |
T |
A |
6: 18,367,382 (GRCm39) |
K1645N |
probably benign |
Het |
| Cttnbp2 |
A |
T |
6: 18,427,467 (GRCm39) |
L738* |
probably null |
Het |
| Cul9 |
T |
A |
17: 46,820,897 (GRCm39) |
T1927S |
probably benign |
Het |
| Cyfip2 |
A |
G |
11: 46,151,707 (GRCm39) |
C531R |
probably benign |
Het |
| Cyp2j6 |
A |
G |
4: 96,414,245 (GRCm39) |
I340T |
probably damaging |
Het |
| Daam1 |
A |
G |
12: 71,992,251 (GRCm39) |
E322G |
unknown |
Het |
| Dab2ip |
T |
A |
2: 35,609,915 (GRCm39) |
L710* |
probably null |
Het |
| Degs1l |
G |
T |
1: 180,882,810 (GRCm39) |
V191F |
possibly damaging |
Het |
| Dph1 |
T |
C |
11: 75,076,825 (GRCm39) |
T60A |
possibly damaging |
Het |
| Eme1 |
T |
C |
11: 94,541,339 (GRCm39) |
D161G |
probably benign |
Het |
| Epha3 |
C |
T |
16: 63,366,510 (GRCm39) |
G980D |
possibly damaging |
Het |
| Eri3 |
T |
A |
4: 117,422,013 (GRCm39) |
V136E |
probably benign |
Het |
| Espl1 |
T |
A |
15: 102,228,233 (GRCm39) |
I1669N |
possibly damaging |
Het |
| Exoc6 |
T |
C |
19: 37,588,071 (GRCm39) |
I568T |
probably damaging |
Het |
| F3 |
T |
A |
3: 121,527,822 (GRCm39) |
L85H |
|
Het |
| Fam186b |
G |
A |
15: 99,177,616 (GRCm39) |
A570V |
probably damaging |
Het |
| Fbxw14 |
T |
C |
9: 109,106,335 (GRCm39) |
Y234C |
probably benign |
Het |
| Fbxw25 |
T |
A |
9: 109,483,676 (GRCm39) |
N179Y |
|
Het |
| Foxr1 |
T |
A |
9: 44,352,199 (GRCm39) |
|
probably benign |
Het |
| Gas8 |
T |
A |
8: 124,263,179 (GRCm39) |
V452E |
possibly damaging |
Het |
| Gdpd4 |
T |
C |
7: 97,649,369 (GRCm39) |
V450A |
probably damaging |
Het |
| Greb1 |
T |
C |
12: 16,774,824 (GRCm39) |
Y191C |
probably benign |
Het |
| H3c11 |
T |
C |
13: 21,967,221 (GRCm39) |
D107G |
probably damaging |
Het |
| Haus3 |
G |
A |
5: 34,325,300 (GRCm39) |
R120W |
probably benign |
Het |
| Herc1 |
G |
T |
9: 66,294,193 (GRCm39) |
|
probably null |
Het |
| Hyal2 |
T |
C |
9: 107,447,844 (GRCm39) |
W166R |
probably damaging |
Het |
| Inka1 |
T |
A |
9: 107,861,488 (GRCm39) |
Y276F |
probably benign |
Het |
| Itga7 |
C |
T |
10: 128,789,669 (GRCm39) |
A1003V |
probably damaging |
Het |
| Itga8 |
T |
A |
2: 12,165,219 (GRCm39) |
I797F |
possibly damaging |
Het |
| Kank2 |
T |
C |
9: 21,705,852 (GRCm39) |
T389A |
possibly damaging |
Het |
| Kcnb2 |
T |
A |
1: 15,779,737 (GRCm39) |
I203N |
probably damaging |
Het |
| Kif21b |
T |
A |
1: 136,077,166 (GRCm39) |
L396Q |
probably damaging |
Het |
| Kng1 |
T |
G |
16: 22,879,170 (GRCm39) |
I78S |
probably damaging |
Het |
| Ldlrad4 |
T |
C |
18: 68,387,551 (GRCm39) |
S288P |
probably benign |
Het |
| Lmntd2 |
A |
G |
7: 140,790,701 (GRCm39) |
S516P |
|
Het |
| Lrp1b |
T |
A |
2: 41,185,711 (GRCm39) |
I1449F |
|
Het |
| Lrrk2 |
T |
A |
15: 91,634,043 (GRCm39) |
I1380K |
possibly damaging |
Het |
| Lvrn |
T |
G |
18: 47,017,506 (GRCm39) |
I612S |
probably damaging |
Het |
| Lyst |
T |
C |
13: 13,812,408 (GRCm39) |
L940P |
probably benign |
Het |
| Man2a2 |
T |
A |
7: 80,006,101 (GRCm39) |
M996L |
probably benign |
Het |
| Map3k3 |
T |
A |
11: 106,041,860 (GRCm39) |
I413N |
probably damaging |
Het |
| Map4k5 |
A |
G |
12: 69,863,167 (GRCm39) |
V629A |
probably benign |
Het |
| Mapre2 |
A |
G |
18: 24,023,981 (GRCm39) |
E325G |
unknown |
Het |
| Mbnl1 |
A |
G |
3: 60,520,715 (GRCm39) |
N101S |
probably benign |
Het |
| Meltf |
T |
A |
16: 31,703,869 (GRCm39) |
C199S |
probably damaging |
Het |
| Mmab |
T |
C |
5: 114,574,850 (GRCm39) |
E141G |
probably benign |
Het |
| Mtcl2 |
G |
A |
2: 156,902,182 (GRCm39) |
R278C |
probably damaging |
Het |
| Mtus2 |
T |
C |
5: 148,250,217 (GRCm39) |
L1317P |
|
Het |
| Muc6 |
T |
A |
7: 141,217,783 (GRCm39) |
T2297S |
possibly damaging |
Het |
| Myom2 |
A |
T |
8: 15,158,399 (GRCm39) |
K784* |
probably null |
Het |
| Nek1 |
A |
G |
8: 61,577,157 (GRCm39) |
E1118G |
probably benign |
Het |
| Nrtn |
A |
G |
17: 57,058,416 (GRCm39) |
V195A |
probably damaging |
Het |
| Nsd3 |
G |
A |
8: 26,204,230 (GRCm39) |
V420I |
|
Het |
| Or52e4 |
T |
C |
7: 104,706,281 (GRCm39) |
L276P |
possibly damaging |
Het |
| Or52z13 |
A |
T |
7: 103,247,225 (GRCm39) |
Q234L |
probably benign |
Het |
| Or5ac23 |
T |
C |
16: 59,149,765 (GRCm39) |
I36V |
probably benign |
Het |
| Or5b99 |
T |
A |
19: 12,976,983 (GRCm39) |
I211N |
probably damaging |
Het |
| Or5t9 |
A |
G |
2: 86,659,098 (GRCm39) |
M1V |
probably null |
Het |
| Or6ae1 |
G |
A |
7: 139,742,233 (GRCm39) |
T210I |
probably damaging |
Het |
| Or6c33 |
T |
C |
10: 129,853,287 (GRCm39) |
I19T |
probably benign |
Het |
| Or8b56 |
A |
T |
9: 38,739,014 (GRCm39) |
H3L |
probably benign |
Het |
| Pde10a |
G |
T |
17: 9,020,710 (GRCm39) |
A216S |
unknown |
Het |
| Phldb2 |
T |
C |
16: 45,645,247 (GRCm39) |
T400A |
possibly damaging |
Het |
| Pkd1l1 |
T |
A |
11: 8,815,502 (GRCm39) |
T1920S |
|
Het |
| Ptgs2 |
T |
A |
1: 149,981,419 (GRCm39) |
N567K |
probably benign |
Het |
| Pwp1 |
T |
A |
10: 85,712,370 (GRCm39) |
D141E |
probably damaging |
Het |
| Rab3ip |
T |
C |
10: 116,754,668 (GRCm39) |
E296G |
probably null |
Het |
| Rb1cc1 |
A |
G |
1: 6,314,339 (GRCm39) |
K337R |
probably benign |
Het |
| Rbp3 |
A |
G |
14: 33,677,477 (GRCm39) |
D475G |
probably damaging |
Het |
| Ric3 |
T |
C |
7: 108,637,997 (GRCm39) |
E253G |
possibly damaging |
Het |
| Rnf214 |
A |
T |
9: 45,811,141 (GRCm39) |
V174E |
possibly damaging |
Het |
| Robo3 |
A |
G |
9: 37,340,900 (GRCm39) |
F124S |
probably damaging |
Het |
| Rrad |
A |
G |
8: 105,355,324 (GRCm39) |
F228S |
probably damaging |
Het |
| Scn3a |
A |
T |
2: 65,291,595 (GRCm39) |
M1717K |
probably damaging |
Het |
| Scn3b |
A |
G |
9: 40,193,729 (GRCm39) |
D152G |
probably benign |
Het |
| Scn5a |
C |
A |
9: 119,315,803 (GRCm39) |
R1635L |
probably damaging |
Het |
| Sec61b |
A |
G |
4: 47,483,049 (GRCm39) |
Y93C |
probably damaging |
Het |
| Shprh |
T |
A |
10: 11,042,235 (GRCm39) |
Y739* |
probably null |
Het |
| Skor2 |
C |
T |
18: 76,946,376 (GRCm39) |
H33Y |
unknown |
Het |
| Slc26a7 |
T |
C |
4: 14,519,496 (GRCm39) |
N508S |
probably benign |
Het |
| Slc7a12 |
A |
G |
3: 14,564,360 (GRCm39) |
I349V |
possibly damaging |
Het |
| Slit1 |
T |
C |
19: 41,596,874 (GRCm39) |
Y1075C |
probably damaging |
Het |
| Sltm |
C |
T |
9: 70,480,841 (GRCm39) |
A231V |
unknown |
Het |
| Smg1 |
A |
G |
7: 117,812,208 (GRCm39) |
S52P |
unknown |
Het |
| Sorl1 |
A |
G |
9: 41,957,893 (GRCm39) |
Y584H |
probably damaging |
Het |
| Spmip2 |
A |
T |
3: 79,356,616 (GRCm39) |
M140L |
probably benign |
Het |
| Ssbp1 |
T |
A |
6: 40,454,968 (GRCm39) |
S142R |
probably benign |
Het |
| Stard3 |
A |
G |
11: 98,270,797 (GRCm39) |
|
probably null |
Het |
| Strn3 |
G |
T |
12: 51,674,300 (GRCm39) |
H531N |
possibly damaging |
Het |
| Stx17 |
A |
G |
4: 48,180,739 (GRCm39) |
T195A |
probably damaging |
Het |
| Tekt2 |
C |
T |
4: 126,217,444 (GRCm39) |
R207H |
probably damaging |
Het |
| Tmed5 |
A |
C |
5: 108,280,100 (GRCm39) |
|
probably null |
Het |
| Tmem132a |
C |
T |
19: 10,838,960 (GRCm39) |
R494H |
probably benign |
Het |
| Tom1 |
A |
G |
8: 75,787,177 (GRCm39) |
K406E |
probably benign |
Het |
| Trav5d-4 |
A |
T |
14: 53,239,473 (GRCm39) |
N43Y |
probably damaging |
Het |
| Trbv19 |
G |
T |
6: 41,155,945 (GRCm39) |
K105N |
possibly damaging |
Het |
| Trim34a |
C |
T |
7: 103,910,328 (GRCm39) |
Q377* |
probably null |
Het |
| Trp53bp2 |
T |
A |
1: 182,276,378 (GRCm39) |
N786K |
probably benign |
Het |
| Trpc3 |
A |
G |
3: 36,705,683 (GRCm39) |
M504T |
probably benign |
Het |
| Ttc28 |
A |
T |
5: 111,371,092 (GRCm39) |
M545L |
probably benign |
Het |
| Uggt1 |
A |
C |
1: 36,204,627 (GRCm39) |
V996G |
possibly damaging |
Het |
| Vmn2r65 |
G |
A |
7: 84,589,880 (GRCm39) |
Q679* |
probably null |
Het |
| Wdfy4 |
T |
C |
14: 32,692,833 (GRCm39) |
I2958V |
|
Het |
| Zbtb37 |
C |
T |
1: 160,847,840 (GRCm39) |
S389N |
possibly damaging |
Het |
| Zfp235 |
T |
C |
7: 23,841,669 (GRCm39) |
V696A |
possibly damaging |
Het |
| Zzef1 |
T |
A |
11: 72,765,732 (GRCm39) |
C1420S |
probably damaging |
Het |
|
| Other mutations in Rictor |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00488:Rictor
|
APN |
15 |
6,816,071 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00785:Rictor
|
APN |
15 |
6,806,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00801:Rictor
|
APN |
15 |
6,824,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01072:Rictor
|
APN |
15 |
6,819,043 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01139:Rictor
|
APN |
15 |
6,807,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01303:Rictor
|
APN |
15 |
6,738,119 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL01307:Rictor
|
APN |
15 |
6,804,085 (GRCm39) |
splice site |
probably null |
|
|
IGL01767:Rictor
|
APN |
15 |
6,806,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01774:Rictor
|
APN |
15 |
6,799,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01800:Rictor
|
APN |
15 |
6,804,182 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02192:Rictor
|
APN |
15 |
6,815,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02503:Rictor
|
APN |
15 |
6,815,924 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02652:Rictor
|
APN |
15 |
6,805,668 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02656:Rictor
|
APN |
15 |
6,806,401 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02752:Rictor
|
APN |
15 |
6,816,852 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03000:Rictor
|
APN |
15 |
6,798,721 (GRCm39) |
splice site |
probably benign |
|
|
IGL03118:Rictor
|
APN |
15 |
6,788,999 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03182:Rictor
|
APN |
15 |
6,819,079 (GRCm39) |
missense |
probably benign |
0.08 |
|
Tense
|
UTSW |
15 |
6,788,977 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Tonus
|
UTSW |
15 |
6,798,815 (GRCm39) |
critical splice donor site |
probably null |
|
|
Torrid
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0149:Rictor
|
UTSW |
15 |
6,813,588 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0288:Rictor
|
UTSW |
15 |
6,816,021 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0304:Rictor
|
UTSW |
15 |
6,815,852 (GRCm39) |
splice site |
probably null |
|
|
R0336:Rictor
|
UTSW |
15 |
6,806,234 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0361:Rictor
|
UTSW |
15 |
6,813,588 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0423:Rictor
|
UTSW |
15 |
6,803,381 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0453:Rictor
|
UTSW |
15 |
6,738,123 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0515:Rictor
|
UTSW |
15 |
6,798,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0630:Rictor
|
UTSW |
15 |
6,823,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0730:Rictor
|
UTSW |
15 |
6,803,467 (GRCm39) |
splice site |
probably benign |
|
|
R0744:Rictor
|
UTSW |
15 |
6,793,759 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0836:Rictor
|
UTSW |
15 |
6,793,759 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0881:Rictor
|
UTSW |
15 |
6,821,151 (GRCm39) |
missense |
probably benign |
|
|
R1114:Rictor
|
UTSW |
15 |
6,823,486 (GRCm39) |
nonsense |
probably null |
|
|
R1367:Rictor
|
UTSW |
15 |
6,820,119 (GRCm39) |
splice site |
probably benign |
|
|
R1655:Rictor
|
UTSW |
15 |
6,801,693 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1678:Rictor
|
UTSW |
15 |
6,785,952 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1679:Rictor
|
UTSW |
15 |
6,797,571 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1754:Rictor
|
UTSW |
15 |
6,764,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1757:Rictor
|
UTSW |
15 |
6,803,343 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1762:Rictor
|
UTSW |
15 |
6,786,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1914:Rictor
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1915:Rictor
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1994:Rictor
|
UTSW |
15 |
6,805,637 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2145:Rictor
|
UTSW |
15 |
6,794,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2182:Rictor
|
UTSW |
15 |
6,801,685 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2191:Rictor
|
UTSW |
15 |
6,789,095 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2357:Rictor
|
UTSW |
15 |
6,813,043 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Rictor
|
UTSW |
15 |
6,799,476 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3082:Rictor
|
UTSW |
15 |
6,804,338 (GRCm39) |
missense |
probably benign |
0.15 |
|
R3885:Rictor
|
UTSW |
15 |
6,789,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3900:Rictor
|
UTSW |
15 |
6,818,954 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4376:Rictor
|
UTSW |
15 |
6,816,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4611:Rictor
|
UTSW |
15 |
6,816,625 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4644:Rictor
|
UTSW |
15 |
6,807,416 (GRCm39) |
nonsense |
probably null |
|
|
R4718:Rictor
|
UTSW |
15 |
6,812,641 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4822:Rictor
|
UTSW |
15 |
6,821,161 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4980:Rictor
|
UTSW |
15 |
6,811,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5034:Rictor
|
UTSW |
15 |
6,797,576 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5179:Rictor
|
UTSW |
15 |
6,825,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5386:Rictor
|
UTSW |
15 |
6,818,985 (GRCm39) |
missense |
probably benign |
0.37 |
|
R5532:Rictor
|
UTSW |
15 |
6,819,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5549:Rictor
|
UTSW |
15 |
6,816,391 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5715:Rictor
|
UTSW |
15 |
6,780,197 (GRCm39) |
nonsense |
probably null |
|
|
R5733:Rictor
|
UTSW |
15 |
6,812,585 (GRCm39) |
missense |
probably benign |
|
|
R5822:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5848:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5849:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5850:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5854:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5855:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5856:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5936:Rictor
|
UTSW |
15 |
6,813,642 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6155:Rictor
|
UTSW |
15 |
6,823,458 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6394:Rictor
|
UTSW |
15 |
6,798,790 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R6549:Rictor
|
UTSW |
15 |
6,825,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6611:Rictor
|
UTSW |
15 |
6,780,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6657:Rictor
|
UTSW |
15 |
6,788,977 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6705:Rictor
|
UTSW |
15 |
6,823,493 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6819:Rictor
|
UTSW |
15 |
6,825,517 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6985:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6989:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7016:Rictor
|
UTSW |
15 |
6,804,361 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7030:Rictor
|
UTSW |
15 |
6,737,934 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7066:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7067:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7216:Rictor
|
UTSW |
15 |
6,798,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7396:Rictor
|
UTSW |
15 |
6,816,462 (GRCm39) |
missense |
not run |
|
|
R7449:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7450:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7452:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7616:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7620:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7643:Rictor
|
UTSW |
15 |
6,798,750 (GRCm39) |
nonsense |
probably null |
|
|
R7699:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7700:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7749:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7750:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7751:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7753:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7841:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7894:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7897:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7898:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7937:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7944:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8062:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8063:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8094:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8119:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8134:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8166:Rictor
|
UTSW |
15 |
6,798,815 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8324:Rictor
|
UTSW |
15 |
6,775,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8343:Rictor
|
UTSW |
15 |
6,807,800 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8691:Rictor
|
UTSW |
15 |
6,816,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8859:Rictor
|
UTSW |
15 |
6,813,067 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8953:Rictor
|
UTSW |
15 |
6,823,928 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8977:Rictor
|
UTSW |
15 |
6,812,566 (GRCm39) |
missense |
probably benign |
|
|
R9008:Rictor
|
UTSW |
15 |
6,801,610 (GRCm39) |
splice site |
probably benign |
|
|
R9369:Rictor
|
UTSW |
15 |
6,773,848 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9695:Rictor
|
UTSW |
15 |
6,816,010 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0020:Rictor
|
UTSW |
15 |
6,785,963 (GRCm39) |
missense |
probably benign |
0.32 |
|
X0060:Rictor
|
UTSW |
15 |
6,816,033 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGTGGTGAGAATAATGTCAATTTCC -3'
(R):5'- CTGAGGAGATGCTATGAGGC -3'
Sequencing Primer
(F):5'- CCAGTTAGGGAAATTCTGAGAATAC -3'
(R):5'- TATGAGGCATGCTGGAGCC -3'
|
| Posted On |
2022-08-09 |
Incidental Mutation