Incidental Mutation 'R9569:Umodl1'
| ID |
721877 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| MMRRC Submission |
068966-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9569 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
31173614-31229684 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 31217143 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 1125
(Y1125C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067443
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066554
AA Change: Y1125C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
AA Change: Y1125C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000066981
AA Change: Y1010C
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
AA Change: Y1010C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000114555
AA Change: Y1125C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
AA Change: Y1125C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abi2 |
T |
A |
1: 60,503,763 (GRCm39) |
V356D |
probably damaging |
Het |
| Adgrd1 |
T |
C |
5: 129,256,701 (GRCm39) |
V690A |
possibly damaging |
Het |
| Apba2 |
T |
C |
7: 64,393,138 (GRCm39) |
M553T |
possibly damaging |
Het |
| Apeh |
C |
T |
9: 107,971,609 (GRCm39) |
V13M |
unknown |
Het |
| Apol11b |
C |
T |
15: 77,524,771 (GRCm39) |
E5K |
possibly damaging |
Het |
| Apol7e |
C |
T |
15: 77,601,933 (GRCm39) |
T177I |
probably damaging |
Het |
| Bltp1 |
T |
C |
3: 37,066,770 (GRCm39) |
M211T |
|
Het |
| Bub1b |
T |
C |
2: 118,468,884 (GRCm39) |
I883T |
probably damaging |
Het |
| C9 |
T |
C |
15: 6,489,062 (GRCm39) |
S140P |
probably damaging |
Het |
| Cbfa2t2 |
T |
A |
2: 154,346,485 (GRCm39) |
I64N |
probably benign |
Het |
| Cd180 |
A |
T |
13: 102,842,486 (GRCm39) |
I511F |
possibly damaging |
Het |
| Cic |
T |
C |
7: 24,972,120 (GRCm39) |
V617A |
possibly damaging |
Het |
| Clca3a2 |
A |
C |
3: 144,513,075 (GRCm39) |
|
probably null |
Het |
| D5Ertd579e |
T |
C |
5: 36,759,979 (GRCm39) |
T1394A |
probably damaging |
Het |
| Dclk1 |
A |
T |
3: 55,387,852 (GRCm39) |
E422D |
probably benign |
Het |
| Depdc5 |
A |
T |
5: 33,025,321 (GRCm39) |
D21V |
probably damaging |
Het |
| Dis3l |
A |
G |
9: 64,236,829 (GRCm39) |
F40S |
unknown |
Het |
| Duox1 |
T |
C |
2: 122,148,971 (GRCm39) |
V82A |
probably benign |
Het |
| Dus2 |
T |
C |
8: 106,771,507 (GRCm39) |
V211A |
probably damaging |
Het |
| Eif2ak4 |
G |
A |
2: 118,251,316 (GRCm39) |
S326N |
probably benign |
Het |
| Fat3 |
A |
C |
9: 15,830,495 (GRCm39) |
L153R |
|
Het |
| Gpx8 |
C |
T |
13: 113,182,125 (GRCm39) |
V103I |
probably damaging |
Het |
| Gtf2a1l |
A |
G |
17: 89,001,948 (GRCm39) |
D268G |
probably benign |
Het |
| Hc |
T |
C |
2: 34,926,359 (GRCm39) |
I342V |
probably benign |
Het |
| Hsp90ab1 |
T |
A |
17: 45,879,878 (GRCm39) |
D546V |
possibly damaging |
Het |
| Ifi206 |
T |
G |
1: 173,314,209 (GRCm39) |
D77A |
|
Het |
| Igfbp1 |
A |
G |
11: 7,147,881 (GRCm39) |
|
probably benign |
Het |
| Kdm3a |
T |
C |
6: 71,584,434 (GRCm39) |
D559G |
probably benign |
Het |
| Kif2a |
A |
G |
13: 107,105,246 (GRCm39) |
I565T |
probably benign |
Het |
| Krt1c |
T |
C |
15: 101,724,924 (GRCm39) |
T229A |
probably damaging |
Het |
| Lcmt2 |
G |
A |
2: 120,970,522 (GRCm39) |
A187V |
probably damaging |
Het |
| Mapk8ip1 |
A |
G |
2: 92,217,599 (GRCm39) |
M241T |
probably benign |
Het |
| Mup15 |
T |
C |
4: 61,357,875 (GRCm39) |
|
probably benign |
Het |
| Myo9b |
T |
C |
8: 71,811,629 (GRCm39) |
V1912A |
probably benign |
Het |
| Naip5 |
T |
A |
13: 100,356,338 (GRCm39) |
E1092D |
probably benign |
Het |
| Naip5 |
T |
C |
13: 100,359,821 (GRCm39) |
T472A |
probably benign |
Het |
| Net1 |
A |
G |
13: 3,938,518 (GRCm39) |
F123S |
probably benign |
Het |
| Or1j8 |
T |
C |
2: 36,191,946 (GRCm39) |
Y132H |
probably damaging |
Het |
| Or52n2 |
C |
T |
7: 104,542,525 (GRCm39) |
M103I |
possibly damaging |
Het |
| Or5h17 |
A |
G |
16: 58,820,228 (GRCm39) |
Y60C |
probably damaging |
Het |
| Pcdhb13 |
T |
C |
18: 37,576,153 (GRCm39) |
F177S |
probably damaging |
Het |
| Pclo |
T |
C |
5: 14,907,065 (GRCm39) |
|
probably null |
Het |
| Perm1 |
A |
G |
4: 156,303,039 (GRCm39) |
T528A |
probably benign |
Het |
| Pik3c2a |
C |
T |
7: 115,957,939 (GRCm39) |
A1116T |
possibly damaging |
Het |
| Prox2 |
G |
A |
12: 85,141,766 (GRCm39) |
Q146* |
probably null |
Het |
| Psd |
A |
T |
19: 46,308,717 (GRCm39) |
C639S |
possibly damaging |
Het |
| Rffl |
T |
A |
11: 82,703,264 (GRCm39) |
T220S |
probably benign |
Het |
| Scn2a |
A |
G |
2: 65,560,622 (GRCm39) |
D1284G |
probably damaging |
Het |
| Scube1 |
T |
C |
15: 83,513,605 (GRCm39) |
Y385C |
probably damaging |
Het |
| Sec14l3 |
A |
T |
11: 4,026,324 (GRCm39) |
D388V |
probably damaging |
Het |
| Slc26a1 |
G |
T |
5: 108,819,460 (GRCm39) |
Q596K |
probably benign |
Het |
| Slc6a19 |
T |
C |
13: 73,834,030 (GRCm39) |
T343A |
probably benign |
Het |
| Slc7a4 |
A |
G |
16: 17,393,262 (GRCm39) |
V179A |
|
Het |
| Sox14 |
T |
G |
9: 99,757,562 (GRCm39) |
D49A |
|
Het |
| Spata31g1 |
G |
C |
4: 42,971,740 (GRCm39) |
V358L |
probably benign |
Het |
| Timm22 |
A |
G |
11: 76,298,196 (GRCm39) |
S56G |
probably benign |
Het |
| Tmub2 |
G |
A |
11: 102,179,153 (GRCm39) |
W322* |
probably null |
Het |
| Tsc22d4 |
A |
G |
5: 137,756,428 (GRCm39) |
T8A |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,539,652 (GRCm39) |
I34445V |
probably benign |
Het |
| Tyms |
A |
T |
5: 30,268,360 (GRCm39) |
Y196* |
probably null |
Het |
| Ube2o |
G |
A |
11: 116,434,823 (GRCm39) |
T546M |
probably damaging |
Het |
| Unc13b |
CGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGC |
CGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGCCAGAGC |
4: 43,177,312 (GRCm39) |
|
probably benign |
Het |
| Unk |
A |
T |
11: 115,950,035 (GRCm39) |
Q747L |
probably damaging |
Het |
| Vmn1r170 |
A |
G |
7: 23,306,294 (GRCm39) |
E232G |
probably benign |
Het |
| Vps41 |
A |
G |
13: 19,013,396 (GRCm39) |
Y338C |
possibly damaging |
Het |
| Washc5 |
T |
C |
15: 59,215,980 (GRCm39) |
M800V |
probably benign |
Het |
| Wt1 |
T |
A |
2: 104,993,711 (GRCm39) |
I348N |
possibly damaging |
Het |
| Xirp2 |
A |
G |
2: 67,341,242 (GRCm39) |
Y1161C |
probably damaging |
Het |
| Xpo7 |
A |
G |
14: 70,906,140 (GRCm39) |
M1001T |
possibly damaging |
Het |
| Yeats2 |
A |
T |
16: 19,972,902 (GRCm39) |
R19W |
probably damaging |
Het |
| Zfp142 |
T |
C |
1: 74,615,386 (GRCm39) |
T476A |
probably damaging |
Het |
| Zfp229 |
T |
C |
17: 21,964,573 (GRCm39) |
W268R |
possibly damaging |
Het |
| Zfp473 |
A |
G |
7: 44,388,971 (GRCm39) |
F50S |
probably damaging |
Het |
| Zfp975 |
A |
T |
7: 42,311,413 (GRCm39) |
M400K |
probably benign |
Het |
| Zkscan5 |
A |
G |
5: 145,144,419 (GRCm39) |
M150V |
probably benign |
Het |
| Znfx1 |
T |
A |
2: 166,897,875 (GRCm39) |
I350F |
|
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,227,724 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
31,215,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
31,215,233 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
31,217,800 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
31,215,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
31,201,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
31,192,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
31,206,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
31,205,091 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
31,187,415 (GRCm39) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
31,217,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
31,208,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
31,205,473 (GRCm39) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
31,215,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
31,203,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0831:Umodl1
|
UTSW |
17 |
31,215,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1078:Umodl1
|
UTSW |
17 |
31,178,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,221,772 (GRCm39) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
31,205,478 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1459:Umodl1
|
UTSW |
17 |
31,201,232 (GRCm39) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
31,178,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
31,206,942 (GRCm39) |
missense |
probably benign |
|
|
R1757:Umodl1
|
UTSW |
17 |
31,227,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1781:Umodl1
|
UTSW |
17 |
31,187,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Umodl1
|
UTSW |
17 |
31,201,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
31,211,128 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
31,211,062 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
31,211,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
31,208,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,221,837 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
31,203,763 (GRCm39) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
31,178,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
31,207,039 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4684:Umodl1
|
UTSW |
17 |
31,217,088 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4769:Umodl1
|
UTSW |
17 |
31,202,976 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4887:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4888:Umodl1
|
UTSW |
17 |
31,218,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
31,205,055 (GRCm39) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
31,205,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
31,203,066 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
31,199,333 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
31,201,263 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
31,213,761 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
31,215,256 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,221,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
31,201,325 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
31,205,121 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6478:Umodl1
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6702:Umodl1
|
UTSW |
17 |
31,205,273 (GRCm39) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
31,218,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
31,201,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
31,201,318 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7219:Umodl1
|
UTSW |
17 |
31,201,236 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7231:Umodl1
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7234:Umodl1
|
UTSW |
17 |
31,205,595 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7392:Umodl1
|
UTSW |
17 |
31,201,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7401:Umodl1
|
UTSW |
17 |
31,217,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
31,173,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
31,205,430 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
31,178,125 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
31,192,666 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
31,205,361 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
31,192,770 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
31,190,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
31,203,806 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
31,202,958 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
31,192,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
31,178,147 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9270:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9341:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
31,215,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9615:Umodl1
|
UTSW |
17 |
31,217,152 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
31,178,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCCCAGGAGATCACTTACATC -3'
(R):5'- TAACTCCTCTCTGTGTGGGAGG -3'
Sequencing Primer
(F):5'- CAGGAGATCACTTACATCTTGTCTG -3'
(R):5'- AGAAGCTGTTCCTCCTAGCTGATTG -3'
|
| Posted On |
2022-08-09 |
Incidental Mutation