Incidental Mutation 'R9612:Mmrn1'
| ID |
724301 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mmrn1
|
| Ensembl Gene |
ENSMUSG00000054641 |
| Gene Name |
multimerin 1 |
| Synonyms |
Emilin4, 4921530G03Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9612 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
60921301-60966362 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 60953408 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 563
(I563N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000119609
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000129603]
[ENSMUST00000204333]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000129603
AA Change: I563N
PolyPhen 2
Score 0.965 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000119609
Gene: ENSMUSG00000054641
AA Change: I563N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
80 |
92 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
193 |
262 |
3.3e-12 |
PFAM |
|
coiled coil region
|
303 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
658 |
688 |
N/A |
INTRINSIC |
|
coiled coil region
|
808 |
846 |
N/A |
INTRINSIC |
|
low complexity region
|
981 |
992 |
N/A |
INTRINSIC |
|
EGF
|
1026 |
1059 |
1.62e-5 |
SMART |
|
C1Q
|
1076 |
1210 |
6.74e-49 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000204333
AA Change: I563N
PolyPhen 2
Score 0.965 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000145156
Gene: ENSMUSG00000054641
AA Change: I563N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
80 |
92 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
193 |
262 |
7.7e-13 |
PFAM |
|
coiled coil region
|
303 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
658 |
688 |
N/A |
INTRINSIC |
|
coiled coil region
|
808 |
846 |
N/A |
INTRINSIC |
|
low complexity region
|
981 |
992 |
N/A |
INTRINSIC |
|
EGF
|
1025 |
1058 |
1.62e-5 |
SMART |
|
C1Q
|
1075 |
1209 |
6.74e-49 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610021A01Rik |
T |
C |
7: 41,276,327 (GRCm39) |
S677P |
possibly damaging |
Het |
| 5730480H06Rik |
A |
G |
5: 48,531,872 (GRCm39) |
I67V |
probably benign |
Het |
| Adam15 |
T |
A |
3: 89,249,247 (GRCm39) |
Y736F |
probably damaging |
Het |
| Adam29 |
A |
T |
8: 56,325,118 (GRCm39) |
F445L |
possibly damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,641,082 (GRCm39) |
Y3318H |
probably damaging |
Het |
| Akap6 |
A |
G |
12: 52,958,690 (GRCm39) |
Y815C |
probably damaging |
Het |
| Ankar |
T |
A |
1: 72,704,294 (GRCm39) |
D876V |
possibly damaging |
Het |
| Atp6v1g2 |
G |
A |
17: 35,456,733 (GRCm39) |
V106I |
probably benign |
Het |
| Bdp1 |
A |
G |
13: 100,214,370 (GRCm39) |
S490P |
probably benign |
Het |
| Bet1 |
A |
T |
6: 4,077,918 (GRCm39) |
V107D |
probably damaging |
Het |
| Bri3bp |
T |
C |
5: 125,531,390 (GRCm39) |
V112A |
probably damaging |
Het |
| Cage1 |
T |
A |
13: 38,216,351 (GRCm39) |
D33V |
probably damaging |
Het |
| Ccdc146 |
G |
T |
5: 21,535,577 (GRCm39) |
A159E |
probably damaging |
Het |
| Ccnl1 |
C |
A |
3: 65,865,404 (GRCm39) |
G49V |
probably damaging |
Het |
| Cdk13 |
A |
C |
13: 17,926,440 (GRCm39) |
F787V |
|
Het |
| Cdk5r1 |
T |
C |
11: 80,368,480 (GRCm39) |
V49A |
probably benign |
Het |
| Cdon |
G |
A |
9: 35,398,201 (GRCm39) |
V973I |
probably damaging |
Het |
| Cfap298 |
A |
T |
16: 90,724,275 (GRCm39) |
M166K |
probably benign |
Het |
| Chd1l |
T |
A |
3: 97,488,463 (GRCm39) |
K518* |
probably null |
Het |
| Col24a1 |
A |
G |
3: 145,250,960 (GRCm39) |
D1653G |
probably benign |
Het |
| Cstf3 |
G |
T |
2: 104,483,370 (GRCm39) |
V359F |
possibly damaging |
Het |
| Dchs2 |
T |
C |
3: 83,178,193 (GRCm39) |
I1082T |
probably damaging |
Het |
| Dlec1 |
A |
T |
9: 118,956,533 (GRCm39) |
I736F |
probably damaging |
Het |
| Dnah9 |
T |
C |
11: 65,818,475 (GRCm39) |
N3288D |
probably benign |
Het |
| Dpcd |
G |
T |
19: 45,560,422 (GRCm39) |
E82* |
probably null |
Het |
| Ehbp1 |
T |
C |
11: 22,119,124 (GRCm39) |
D182G |
probably damaging |
Het |
| Eif1ad13 |
A |
G |
12: 87,762,507 (GRCm39) |
I76V |
probably benign |
Het |
| Evc2 |
G |
T |
5: 37,544,130 (GRCm39) |
E626D |
probably benign |
Het |
| Evi5 |
T |
C |
5: 107,943,578 (GRCm39) |
E589G |
probably benign |
Het |
| Exoc4 |
T |
C |
6: 33,226,161 (GRCm39) |
I25T |
probably benign |
Het |
| Extl2 |
T |
A |
3: 115,821,145 (GRCm39) |
*331R |
probably null |
Het |
| Fkbp8 |
G |
A |
8: 70,984,324 (GRCm39) |
R225H |
probably damaging |
Het |
| Foxred2 |
A |
T |
15: 77,836,206 (GRCm39) |
S384T |
probably damaging |
Het |
| Garre1 |
A |
T |
7: 33,947,656 (GRCm39) |
C451S |
probably damaging |
Het |
| Glmn |
T |
C |
5: 107,741,731 (GRCm39) |
E18G |
probably damaging |
Het |
| Gm7489 |
A |
C |
15: 53,749,369 (GRCm39) |
Q147P |
unknown |
Het |
| Gm7489 |
C |
A |
15: 53,749,368 (GRCm39) |
Q147K |
unknown |
Het |
| Gm8005 |
T |
A |
14: 42,260,355 (GRCm39) |
I94F |
|
Het |
| Golgb1 |
G |
A |
16: 36,739,967 (GRCm39) |
V2810M |
probably benign |
Het |
| Gpr21 |
T |
C |
2: 37,408,399 (GRCm39) |
L315P |
probably damaging |
Het |
| Grip1 |
G |
A |
10: 119,874,569 (GRCm39) |
E778K |
possibly damaging |
Het |
| Herc6 |
T |
G |
6: 57,629,017 (GRCm39) |
S643A |
probably benign |
Het |
| Igkv14-100 |
T |
A |
6: 68,496,317 (GRCm39) |
I70N |
probably damaging |
Het |
| Kcnn3 |
A |
G |
3: 89,516,703 (GRCm39) |
M371V |
probably benign |
Het |
| Kif1a |
T |
A |
1: 92,953,416 (GRCm39) |
H1256L |
probably damaging |
Het |
| Klhdc4 |
A |
G |
8: 122,527,917 (GRCm39) |
S266P |
possibly damaging |
Het |
| Kmt2d |
CTGTTG |
CTG |
15: 98,743,057 (GRCm39) |
|
probably benign |
Het |
| Lefty2 |
T |
A |
1: 180,722,286 (GRCm39) |
L208Q |
probably damaging |
Het |
| Lingo2 |
T |
C |
4: 35,708,450 (GRCm39) |
Y510C |
probably damaging |
Het |
| Lrif1 |
T |
A |
3: 106,639,200 (GRCm39) |
V70D |
probably damaging |
Het |
| Lrrc74a |
A |
T |
12: 86,805,345 (GRCm39) |
K389I |
possibly damaging |
Het |
| Megf8 |
A |
T |
7: 25,054,488 (GRCm39) |
E1868V |
probably benign |
Het |
| Mmp1a |
TG |
TGG |
9: 7,465,083 (GRCm38) |
|
probably null |
Het |
| Mmp8 |
A |
G |
9: 7,560,608 (GRCm39) |
D95G |
probably damaging |
Het |
| Mroh3 |
T |
C |
1: 136,118,713 (GRCm39) |
T535A |
probably benign |
Het |
| Mroh9 |
A |
G |
1: 162,866,498 (GRCm39) |
L715P |
probably damaging |
Het |
| Myh6 |
G |
T |
14: 55,201,054 (GRCm39) |
A136E |
probably benign |
Het |
| Myom1 |
G |
T |
17: 71,412,475 (GRCm39) |
E1231* |
probably null |
Het |
| Nod2 |
G |
T |
8: 89,397,101 (GRCm39) |
C837F |
probably benign |
Het |
| Nos2 |
T |
A |
11: 78,839,984 (GRCm39) |
W698R |
probably damaging |
Het |
| Nup210l |
C |
T |
3: 90,107,173 (GRCm39) |
P1570L |
probably benign |
Het |
| Oas1a |
A |
T |
5: 121,040,028 (GRCm39) |
S188T |
possibly damaging |
Het |
| Ogfr |
GGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGG |
GGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGG |
2: 180,237,059 (GRCm39) |
|
probably benign |
Het |
| Opa1 |
T |
C |
16: 29,430,255 (GRCm39) |
M394T |
|
Het |
| Or1e1d-ps1 |
T |
A |
11: 73,819,375 (GRCm39) |
D108E |
possibly damaging |
Het |
| Or5an6 |
A |
T |
19: 12,371,983 (GRCm39) |
M119L |
probably damaging |
Het |
| Or5p66 |
A |
G |
7: 107,885,487 (GRCm39) |
M282T |
probably benign |
Het |
| Or7g21 |
T |
A |
9: 19,032,760 (GRCm39) |
S167T |
probably benign |
Het |
| Or7g29 |
A |
G |
9: 19,286,677 (GRCm39) |
S167P |
possibly damaging |
Het |
| Oxct2a |
T |
A |
4: 123,217,129 (GRCm39) |
D84V |
probably damaging |
Het |
| Oxct2b |
A |
C |
4: 123,011,019 (GRCm39) |
D313A |
probably damaging |
Het |
| Phldb3 |
G |
A |
7: 24,328,372 (GRCm39) |
V639M |
probably damaging |
Het |
| Plppr4 |
T |
A |
3: 117,115,610 (GRCm39) |
N749I |
probably benign |
Het |
| Pmp22 |
G |
T |
11: 63,024,065 (GRCm39) |
V25F |
probably benign |
Het |
| Pofut2 |
A |
T |
10: 77,101,763 (GRCm39) |
M267L |
probably benign |
Het |
| Ppp1r42 |
T |
A |
1: 10,039,067 (GRCm39) |
N351I |
possibly damaging |
Het |
| Prl2b1 |
T |
C |
13: 27,572,479 (GRCm39) |
E37G |
probably benign |
Het |
| Ptpro |
G |
T |
6: 137,391,318 (GRCm39) |
V813F |
probably benign |
Het |
| Rnaseh2c |
T |
C |
19: 5,652,343 (GRCm39) |
F99L |
probably benign |
Het |
| Scn9a |
T |
A |
2: 66,363,708 (GRCm39) |
I857F |
probably damaging |
Het |
| Slf1 |
A |
G |
13: 77,197,204 (GRCm39) |
|
probably null |
Het |
| Smyd2 |
T |
C |
1: 189,612,983 (GRCm39) |
*434W |
probably null |
Het |
| Spata31h1 |
T |
A |
10: 82,125,453 (GRCm39) |
N2519I |
possibly damaging |
Het |
| Stk40 |
A |
G |
4: 126,030,650 (GRCm39) |
D290G |
probably damaging |
Het |
| Tdo2 |
C |
A |
3: 81,879,001 (GRCm39) |
W82C |
probably damaging |
Het |
| Tmem101 |
A |
G |
11: 102,044,194 (GRCm39) |
V231A |
probably damaging |
Het |
| Tns2 |
G |
A |
15: 102,015,577 (GRCm39) |
E160K |
probably damaging |
Het |
| Trim31 |
A |
T |
17: 37,212,551 (GRCm39) |
D174V |
probably benign |
Het |
| Unc13d |
A |
T |
11: 115,961,144 (GRCm39) |
Y404* |
probably null |
Het |
| Ush2a |
C |
A |
1: 188,092,063 (GRCm39) |
Y531* |
probably null |
Het |
| Vapa |
G |
A |
17: 65,889,736 (GRCm39) |
P144S |
probably benign |
Het |
| Vmn1r212 |
C |
T |
13: 23,067,443 (GRCm39) |
V297M |
possibly damaging |
Het |
| Vmn2r80 |
A |
C |
10: 79,030,712 (GRCm39) |
N846T |
probably damaging |
Het |
| Zfp811 |
A |
G |
17: 33,017,740 (GRCm39) |
V100A |
probably benign |
Het |
| Zfp958 |
T |
A |
8: 4,678,298 (GRCm39) |
C108S |
probably damaging |
Het |
| Zic5 |
G |
A |
14: 122,697,100 (GRCm39) |
T505I |
unknown |
Het |
|
| Other mutations in Mmrn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00640:Mmrn1
|
APN |
6 |
60,954,497 (GRCm39) |
missense |
probably benign |
|
|
IGL00742:Mmrn1
|
APN |
6 |
60,935,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00917:Mmrn1
|
APN |
6 |
60,952,894 (GRCm39) |
nonsense |
probably null |
|
|
IGL01121:Mmrn1
|
APN |
6 |
60,952,928 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01393:Mmrn1
|
APN |
6 |
60,937,692 (GRCm39) |
splice site |
probably benign |
|
|
IGL01697:Mmrn1
|
APN |
6 |
60,953,477 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01737:Mmrn1
|
APN |
6 |
60,954,145 (GRCm39) |
missense |
probably benign |
|
|
IGL01944:Mmrn1
|
APN |
6 |
60,948,167 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01987:Mmrn1
|
APN |
6 |
60,921,557 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02005:Mmrn1
|
APN |
6 |
60,937,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02190:Mmrn1
|
APN |
6 |
60,964,177 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02335:Mmrn1
|
APN |
6 |
60,954,131 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL02421:Mmrn1
|
APN |
6 |
60,921,806 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02530:Mmrn1
|
APN |
6 |
60,935,160 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL02709:Mmrn1
|
APN |
6 |
60,950,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03139:Mmrn1
|
APN |
6 |
60,953,324 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03228:Mmrn1
|
APN |
6 |
60,921,876 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03272:Mmrn1
|
APN |
6 |
60,965,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03410:Mmrn1
|
APN |
6 |
60,952,819 (GRCm39) |
missense |
probably benign |
0.36 |
|
H8562:Mmrn1
|
UTSW |
6 |
60,935,164 (GRCm39) |
missense |
probably damaging |
0.98 |
|
K2124:Mmrn1
|
UTSW |
6 |
60,953,017 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0145:Mmrn1
|
UTSW |
6 |
60,949,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0164:Mmrn1
|
UTSW |
6 |
60,952,799 (GRCm39) |
splice site |
probably benign |
|
|
R0352:Mmrn1
|
UTSW |
6 |
60,921,955 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0400:Mmrn1
|
UTSW |
6 |
60,954,099 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0538:Mmrn1
|
UTSW |
6 |
60,953,453 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0907:Mmrn1
|
UTSW |
6 |
60,950,103 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1117:Mmrn1
|
UTSW |
6 |
60,953,309 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1383:Mmrn1
|
UTSW |
6 |
60,953,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mmrn1
|
UTSW |
6 |
60,922,102 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1591:Mmrn1
|
UTSW |
6 |
60,921,755 (GRCm39) |
nonsense |
probably null |
|
|
R1599:Mmrn1
|
UTSW |
6 |
60,922,021 (GRCm39) |
missense |
probably benign |
|
|
R1733:Mmrn1
|
UTSW |
6 |
60,954,085 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2005:Mmrn1
|
UTSW |
6 |
60,953,068 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2056:Mmrn1
|
UTSW |
6 |
60,921,789 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2144:Mmrn1
|
UTSW |
6 |
60,922,059 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R2299:Mmrn1
|
UTSW |
6 |
60,953,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3836:Mmrn1
|
UTSW |
6 |
60,921,831 (GRCm39) |
missense |
probably benign |
|
|
R3837:Mmrn1
|
UTSW |
6 |
60,921,831 (GRCm39) |
missense |
probably benign |
|
|
R4206:Mmrn1
|
UTSW |
6 |
60,935,164 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4414:Mmrn1
|
UTSW |
6 |
60,921,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4590:Mmrn1
|
UTSW |
6 |
60,937,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4707:Mmrn1
|
UTSW |
6 |
60,965,457 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4820:Mmrn1
|
UTSW |
6 |
60,950,027 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4880:Mmrn1
|
UTSW |
6 |
60,953,423 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5166:Mmrn1
|
UTSW |
6 |
60,953,474 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5324:Mmrn1
|
UTSW |
6 |
60,953,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5887:Mmrn1
|
UTSW |
6 |
60,964,058 (GRCm39) |
missense |
probably benign |
|
|
R5917:Mmrn1
|
UTSW |
6 |
60,950,134 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6108:Mmrn1
|
UTSW |
6 |
60,952,960 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6539:Mmrn1
|
UTSW |
6 |
60,964,168 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6996:Mmrn1
|
UTSW |
6 |
60,954,367 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7064:Mmrn1
|
UTSW |
6 |
60,965,524 (GRCm39) |
nonsense |
probably null |
|
|
R7073:Mmrn1
|
UTSW |
6 |
60,965,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7213:Mmrn1
|
UTSW |
6 |
60,921,527 (GRCm39) |
start gained |
probably benign |
|
|
R7256:Mmrn1
|
UTSW |
6 |
60,953,098 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7324:Mmrn1
|
UTSW |
6 |
60,921,917 (GRCm39) |
nonsense |
probably null |
|
|
R7350:Mmrn1
|
UTSW |
6 |
60,953,320 (GRCm39) |
nonsense |
probably null |
|
|
R7388:Mmrn1
|
UTSW |
6 |
60,953,236 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7652:Mmrn1
|
UTSW |
6 |
60,954,490 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7664:Mmrn1
|
UTSW |
6 |
60,953,689 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7810:Mmrn1
|
UTSW |
6 |
60,953,309 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7832:Mmrn1
|
UTSW |
6 |
60,964,044 (GRCm39) |
splice site |
probably null |
|
|
R7979:Mmrn1
|
UTSW |
6 |
60,952,961 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8071:Mmrn1
|
UTSW |
6 |
60,921,508 (GRCm39) |
start gained |
probably benign |
|
|
R8130:Mmrn1
|
UTSW |
6 |
60,937,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8277:Mmrn1
|
UTSW |
6 |
60,954,220 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8353:Mmrn1
|
UTSW |
6 |
60,965,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8453:Mmrn1
|
UTSW |
6 |
60,965,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8472:Mmrn1
|
UTSW |
6 |
60,965,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8758:Mmrn1
|
UTSW |
6 |
60,964,193 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R8803:Mmrn1
|
UTSW |
6 |
60,965,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8879:Mmrn1
|
UTSW |
6 |
60,953,513 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8907:Mmrn1
|
UTSW |
6 |
60,953,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8983:Mmrn1
|
UTSW |
6 |
60,953,042 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9200:Mmrn1
|
UTSW |
6 |
60,953,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9287:Mmrn1
|
UTSW |
6 |
60,952,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9387:Mmrn1
|
UTSW |
6 |
60,935,176 (GRCm39) |
nonsense |
probably null |
|
|
R9674:Mmrn1
|
UTSW |
6 |
60,948,072 (GRCm39) |
nonsense |
probably null |
|
|
X0026:Mmrn1
|
UTSW |
6 |
60,952,997 (GRCm39) |
missense |
probably benign |
0.09 |
|
Z1176:Mmrn1
|
UTSW |
6 |
60,922,018 (GRCm39) |
missense |
probably benign |
0.37 |
|
Z1177:Mmrn1
|
UTSW |
6 |
60,964,082 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACACACAGCTGTTATCAGTTCTAC -3'
(R):5'- GCAAAGGCTGAAGGATCTCC -3'
Sequencing Primer
(F):5'- TCAGTTCTACAAGTATCAGGAACAG -3'
(R):5'- AGGCTGAAGGATCTCCATGTC -3'
|
| Posted On |
2022-09-12 |
Incidental Mutation