Incidental Mutation 'R9621:Pik3c2b'
| ID |
724760 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pik3c2b
|
| Ensembl Gene |
ENSMUSG00000026447 |
| Gene Name |
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta |
| Synonyms |
PI3K-C2beta, C330011J12Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.219)
|
| Stock # |
R9621 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
132973410-133036429 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 132999345 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 398
(S398P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000076911
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000077730]
[ENSMUST00000153707]
|
| AlphaFold |
E9QAN8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000077730
AA Change: S398P
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000076911
Gene: ENSMUSG00000026447
AA Change: S398P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
155 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
168 |
183 |
N/A |
INTRINSIC |
|
PI3K_rbd
|
363 |
465 |
2.15e-19 |
SMART |
|
PI3K_C2
|
618 |
726 |
6.17e-29 |
SMART |
|
PI3Ka
|
804 |
990 |
1.66e-84 |
SMART |
|
PI3Kc
|
1078 |
1340 |
3.45e-132 |
SMART |
|
PX
|
1364 |
1476 |
9.44e-27 |
SMART |
|
low complexity region
|
1481 |
1492 |
N/A |
INTRINSIC |
|
C2
|
1517 |
1622 |
1.82e-18 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000153707
|
| SMART Domains |
Protein: ENSMUSP00000115469
Gene: ENSMUSG00000026447
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
155 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
168 |
183 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal epidermal growth, differentiation and function. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca1 |
T |
C |
4: 53,092,918 (GRCm39) |
T289A |
probably benign |
Het |
| Adnp |
A |
T |
2: 168,024,663 (GRCm39) |
S877R |
probably benign |
Het |
| Akap13 |
T |
A |
7: 75,386,090 (GRCm39) |
H555Q |
probably benign |
Het |
| Alg6 |
T |
A |
4: 99,615,131 (GRCm39) |
Y38* |
probably null |
Het |
| Amtn |
C |
A |
5: 88,528,205 (GRCm39) |
Q93K |
probably benign |
Het |
| Ap2b1 |
T |
C |
11: 83,293,424 (GRCm39) |
V937A |
probably damaging |
Het |
| Arih1 |
ATCGTCCGGCTCGTCCTCGTCGTCGTCC |
ATCGTCC |
9: 59,393,520 (GRCm39) |
|
probably benign |
Het |
| Atosa |
A |
G |
9: 74,917,512 (GRCm39) |
N711D |
possibly damaging |
Het |
| Bhmt |
A |
G |
13: 93,758,079 (GRCm39) |
S211P |
possibly damaging |
Het |
| Bltp3a |
T |
A |
17: 28,105,753 (GRCm39) |
S760T |
probably benign |
Het |
| Bmp1 |
T |
C |
14: 70,715,306 (GRCm39) |
Y943C |
probably benign |
Het |
| Calcoco2 |
TCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTTCTCCCAGGAGGCCTTCTCTTCC |
TCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTTCTCCCAGGAGGCCTTCTCTTCC |
11: 95,990,862 (GRCm39) |
|
probably null |
Het |
| Cbfb |
A |
C |
8: 105,905,243 (GRCm39) |
T62P |
probably damaging |
Het |
| Ccdc154 |
T |
C |
17: 25,386,355 (GRCm39) |
F249L |
probably damaging |
Het |
| Cdh26 |
T |
A |
2: 178,111,983 (GRCm39) |
F514L |
probably damaging |
Het |
| Cdhr2 |
A |
G |
13: 54,866,350 (GRCm39) |
E352G |
|
Het |
| Cep295nl |
G |
A |
11: 118,224,766 (GRCm39) |
P26L |
possibly damaging |
Het |
| Cfdp1 |
A |
G |
8: 112,571,807 (GRCm39) |
V34A |
probably damaging |
Het |
| Cntnap2 |
A |
T |
6: 46,965,726 (GRCm39) |
I846F |
probably damaging |
Het |
| Cntrl |
A |
G |
2: 35,050,278 (GRCm39) |
K1464E |
probably damaging |
Het |
| Crybg3 |
T |
C |
16: 59,326,613 (GRCm39) |
D1039G |
possibly damaging |
Het |
| Csmd3 |
A |
T |
15: 47,713,116 (GRCm39) |
S778R |
|
Het |
| Daam2 |
C |
T |
17: 49,780,332 (GRCm39) |
C729Y |
probably damaging |
Het |
| Ddx18 |
T |
C |
1: 121,489,132 (GRCm39) |
H305R |
probably damaging |
Het |
| Dio1 |
C |
T |
4: 107,149,558 (GRCm39) |
C248Y |
probably benign |
Het |
| Dnah1 |
C |
A |
14: 31,016,772 (GRCm39) |
A1582S |
probably damaging |
Het |
| Eef1a1 |
A |
T |
9: 78,386,632 (GRCm39) |
D319E |
probably benign |
Het |
| Fam171b |
G |
A |
2: 83,643,109 (GRCm39) |
R6H |
probably damaging |
Het |
| Flnb |
G |
A |
14: 7,926,421 (GRCm38) |
G1822R |
probably damaging |
Het |
| Gabrb1 |
G |
A |
5: 72,279,363 (GRCm39) |
V303I |
possibly damaging |
Het |
| Gli3 |
T |
G |
13: 15,901,253 (GRCm39) |
S1547A |
probably benign |
Het |
| Gm4884 |
A |
T |
7: 40,693,111 (GRCm39) |
N360I |
possibly damaging |
Het |
| Ift70b |
T |
C |
2: 75,768,144 (GRCm39) |
Y203C |
probably damaging |
Het |
| Il1rl2 |
CTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATT |
CTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATT |
1: 40,366,470 (GRCm39) |
|
probably benign |
Het |
| Ino80 |
C |
G |
2: 119,280,496 (GRCm39) |
K289N |
probably damaging |
Het |
| Itpr1 |
G |
A |
6: 108,393,870 (GRCm39) |
E1638K |
probably damaging |
Het |
| Jakmip1 |
A |
T |
5: 37,274,812 (GRCm39) |
I45F |
unknown |
Het |
| Kif1a |
G |
A |
1: 92,983,445 (GRCm39) |
P684L |
probably benign |
Het |
| Kpnb1 |
A |
T |
11: 97,058,460 (GRCm39) |
S610T |
probably benign |
Het |
| Man1a2 |
A |
G |
3: 100,591,961 (GRCm39) |
V73A |
probably benign |
Het |
| Mbtps1 |
A |
G |
8: 120,235,621 (GRCm39) |
V1019A |
possibly damaging |
Het |
| Muc21 |
T |
A |
17: 35,932,720 (GRCm39) |
T489S |
unknown |
Het |
| Nup210 |
G |
C |
6: 90,994,375 (GRCm39) |
N1774K |
probably benign |
Het |
| Or10p21 |
G |
T |
10: 128,847,759 (GRCm39) |
V202F |
probably benign |
Het |
| Pmpca |
A |
G |
2: 26,279,988 (GRCm39) |
T37A |
probably benign |
Het |
| Ppfia1 |
A |
G |
7: 144,052,516 (GRCm39) |
S840P |
probably damaging |
Het |
| Prkcq |
A |
T |
2: 11,261,014 (GRCm39) |
K355N |
probably benign |
Het |
| Prorp |
C |
A |
12: 55,429,042 (GRCm39) |
H538N |
probably benign |
Het |
| Ptprg |
A |
G |
14: 12,237,809 (GRCm38) |
K1422R |
probably benign |
Het |
| Ptprq |
T |
C |
10: 107,378,523 (GRCm39) |
E2006G |
probably damaging |
Het |
| Qsox1 |
TG |
T |
1: 155,671,135 (GRCm39) |
|
probably null |
Het |
| Rcor2 |
A |
T |
19: 7,251,591 (GRCm39) |
T412S |
probably benign |
Het |
| Rnf224 |
A |
T |
2: 25,126,200 (GRCm39) |
M51K |
probably benign |
Het |
| Robo4 |
A |
G |
9: 37,317,509 (GRCm39) |
D521G |
probably damaging |
Het |
| Sf3b4 |
T |
A |
3: 96,084,115 (GRCm39) |
S360T |
unknown |
Het |
| Sgo2b |
T |
C |
8: 64,380,651 (GRCm39) |
D727G |
probably damaging |
Het |
| Smpd2 |
C |
A |
10: 41,364,283 (GRCm39) |
V172L |
probably benign |
Het |
| Spring1 |
C |
T |
5: 118,393,880 (GRCm39) |
T86I |
possibly damaging |
Het |
| Syne1 |
C |
T |
10: 5,273,887 (GRCm39) |
A1966T |
probably benign |
Het |
| Syt13 |
G |
A |
2: 92,745,575 (GRCm39) |
G15D |
possibly damaging |
Het |
| Taf3 |
A |
T |
2: 9,923,070 (GRCm39) |
L18Q |
unknown |
Het |
| Tcam1 |
T |
A |
11: 106,176,259 (GRCm39) |
N328K |
probably damaging |
Het |
| Tekt2 |
C |
T |
4: 126,217,444 (GRCm39) |
R207H |
probably damaging |
Het |
| Tet2 |
A |
T |
3: 133,193,767 (GRCm39) |
Y222* |
probably null |
Het |
| Timm29 |
A |
T |
9: 21,504,218 (GRCm39) |
|
probably benign |
Het |
| Tmc6 |
T |
C |
11: 117,669,995 (GRCm39) |
D17G |
probably benign |
Het |
| Tmem30a |
T |
A |
9: 79,687,926 (GRCm39) |
D81V |
probably benign |
Het |
| Tnnt1 |
T |
C |
7: 4,511,501 (GRCm39) |
I195V |
probably benign |
Het |
| Ttll5 |
T |
A |
12: 85,938,896 (GRCm39) |
V398E |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,748,441 (GRCm39) |
T4203A |
possibly damaging |
Het |
| Ubc |
A |
G |
5: 125,464,511 (GRCm39) |
I272T |
probably damaging |
Het |
| Unc45a |
A |
G |
7: 79,983,785 (GRCm39) |
L337P |
probably damaging |
Het |
| Vmn1r229 |
T |
C |
17: 21,035,315 (GRCm39) |
F187L |
probably benign |
Het |
| Wrn |
A |
T |
8: 33,814,301 (GRCm39) |
M381K |
probably benign |
Het |
| Zdbf2 |
A |
G |
1: 63,342,635 (GRCm39) |
N338S |
possibly damaging |
Het |
| Zfp541 |
A |
G |
7: 15,805,892 (GRCm39) |
E9G |
possibly damaging |
Het |
| Zrsr2-ps1 |
G |
A |
11: 22,923,418 (GRCm39) |
R64Q |
possibly damaging |
Het |
| Zswim8 |
T |
A |
14: 20,772,231 (GRCm39) |
S1614T |
probably benign |
Het |
|
| Other mutations in Pik3c2b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01086:Pik3c2b
|
APN |
1 |
133,019,356 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01288:Pik3c2b
|
APN |
1 |
133,022,543 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01313:Pik3c2b
|
APN |
1 |
132,999,369 (GRCm39) |
nonsense |
probably null |
|
|
IGL01367:Pik3c2b
|
APN |
1 |
133,033,726 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02379:Pik3c2b
|
APN |
1 |
133,022,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02638:Pik3c2b
|
APN |
1 |
133,005,056 (GRCm39) |
splice site |
probably benign |
|
|
IGL02728:Pik3c2b
|
APN |
1 |
133,020,065 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02992:Pik3c2b
|
APN |
1 |
132,994,718 (GRCm39) |
nonsense |
probably null |
|
|
IGL03121:Pik3c2b
|
APN |
1 |
133,007,483 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0453:Pik3c2b
|
UTSW |
1 |
133,005,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0518:Pik3c2b
|
UTSW |
1 |
133,033,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0616:Pik3c2b
|
UTSW |
1 |
133,028,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0659:Pik3c2b
|
UTSW |
1 |
132,998,938 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1542:Pik3c2b
|
UTSW |
1 |
133,017,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1716:Pik3c2b
|
UTSW |
1 |
133,022,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1728:Pik3c2b
|
UTSW |
1 |
132,994,365 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1729:Pik3c2b
|
UTSW |
1 |
132,994,365 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1730:Pik3c2b
|
UTSW |
1 |
132,994,365 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1739:Pik3c2b
|
UTSW |
1 |
132,994,365 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1762:Pik3c2b
|
UTSW |
1 |
132,994,365 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1783:Pik3c2b
|
UTSW |
1 |
132,994,365 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1784:Pik3c2b
|
UTSW |
1 |
132,994,365 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1785:Pik3c2b
|
UTSW |
1 |
132,994,365 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1816:Pik3c2b
|
UTSW |
1 |
133,029,108 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1897:Pik3c2b
|
UTSW |
1 |
132,994,654 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R2006:Pik3c2b
|
UTSW |
1 |
132,994,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2067:Pik3c2b
|
UTSW |
1 |
133,027,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Pik3c2b
|
UTSW |
1 |
133,031,166 (GRCm39) |
missense |
probably benign |
|
|
R2294:Pik3c2b
|
UTSW |
1 |
132,994,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2320:Pik3c2b
|
UTSW |
1 |
133,031,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4735:Pik3c2b
|
UTSW |
1 |
132,994,787 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4926:Pik3c2b
|
UTSW |
1 |
133,027,364 (GRCm39) |
nonsense |
probably null |
|
|
R4948:Pik3c2b
|
UTSW |
1 |
133,027,453 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4997:Pik3c2b
|
UTSW |
1 |
133,032,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5304:Pik3c2b
|
UTSW |
1 |
132,998,146 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R5461:Pik3c2b
|
UTSW |
1 |
133,027,440 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5722:Pik3c2b
|
UTSW |
1 |
133,031,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5971:Pik3c2b
|
UTSW |
1 |
133,002,365 (GRCm39) |
splice site |
probably null |
|
|
R5980:Pik3c2b
|
UTSW |
1 |
133,016,046 (GRCm39) |
missense |
probably benign |
0.43 |
|
R6036:Pik3c2b
|
UTSW |
1 |
133,018,451 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6138:Pik3c2b
|
UTSW |
1 |
133,002,365 (GRCm39) |
splice site |
probably null |
|
|
R6223:Pik3c2b
|
UTSW |
1 |
132,998,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6273:Pik3c2b
|
UTSW |
1 |
132,994,449 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6742:Pik3c2b
|
UTSW |
1 |
133,003,559 (GRCm39) |
missense |
probably benign |
|
|
R6954:Pik3c2b
|
UTSW |
1 |
132,994,041 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6998:Pik3c2b
|
UTSW |
1 |
133,030,110 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7103:Pik3c2b
|
UTSW |
1 |
133,033,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7133:Pik3c2b
|
UTSW |
1 |
133,017,972 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7161:Pik3c2b
|
UTSW |
1 |
133,033,850 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7183:Pik3c2b
|
UTSW |
1 |
132,994,203 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7193:Pik3c2b
|
UTSW |
1 |
133,007,512 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7252:Pik3c2b
|
UTSW |
1 |
133,022,472 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7263:Pik3c2b
|
UTSW |
1 |
133,017,940 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7404:Pik3c2b
|
UTSW |
1 |
133,018,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7709:Pik3c2b
|
UTSW |
1 |
133,007,579 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7712:Pik3c2b
|
UTSW |
1 |
133,013,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7823:Pik3c2b
|
UTSW |
1 |
133,030,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7831:Pik3c2b
|
UTSW |
1 |
132,998,980 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7913:Pik3c2b
|
UTSW |
1 |
133,017,799 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7916:Pik3c2b
|
UTSW |
1 |
133,028,642 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7960:Pik3c2b
|
UTSW |
1 |
133,031,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7981:Pik3c2b
|
UTSW |
1 |
133,003,547 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8346:Pik3c2b
|
UTSW |
1 |
133,017,984 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8938:Pik3c2b
|
UTSW |
1 |
133,016,068 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8997:Pik3c2b
|
UTSW |
1 |
133,018,517 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9416:Pik3c2b
|
UTSW |
1 |
133,005,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9598:Pik3c2b
|
UTSW |
1 |
133,012,725 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9742:Pik3c2b
|
UTSW |
1 |
133,022,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9776:Pik3c2b
|
UTSW |
1 |
133,018,588 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R9786:Pik3c2b
|
UTSW |
1 |
133,019,338 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
U15987:Pik3c2b
|
UTSW |
1 |
133,002,365 (GRCm39) |
splice site |
probably null |
|
|
X0060:Pik3c2b
|
UTSW |
1 |
133,012,674 (GRCm39) |
missense |
probably benign |
0.18 |
|
Z1176:Pik3c2b
|
UTSW |
1 |
133,027,424 (GRCm39) |
nonsense |
probably null |
|
|
Z1176:Pik3c2b
|
UTSW |
1 |
132,994,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGAGGCAGGGAGGACTATTC -3'
(R):5'- CCAGAAGGCAAGTGTCACTTC -3'
Sequencing Primer
(F):5'- TCTGTCGCCTGAATGAAGAC -3'
(R):5'- GAAGGCAAGTGTCACTTCAGTCTC -3'
|
| Posted On |
2022-09-12 |
Incidental Mutation