Incidental Mutation 'R9629:Kirrel1'
| ID |
725329 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kirrel1
|
| Ensembl Gene |
ENSMUSG00000041734 |
| Gene Name |
kirre like nephrin family adhesion molecule 1 |
| Synonyms |
6720469N11Rik, Neph1, Kirrel1, Kirrel |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9629 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
86985900-87082054 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
C to A
at 87003025 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Stop codon
at position 123
(E123*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125525
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041732]
[ENSMUST00000107618]
[ENSMUST00000159976]
|
| AlphaFold |
Q80W68 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000041732
AA Change: E123*
|
| SMART Domains |
Protein: ENSMUSP00000043756
Gene: ENSMUSG00000041734
AA Change: E123*
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000107618
AA Change: E123*
|
| SMART Domains |
Protein: ENSMUSP00000103243
Gene: ENSMUSG00000041734
AA Change: E123*
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000159976
AA Change: E123*
|
| SMART Domains |
Protein: ENSMUSP00000125525
Gene: ENSMUSG00000041734
AA Change: E123*
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene trap insertion exhibit postnatal lethality and are small and sickly. Glomerular and tubular defects in the kidney result in severe proteinuria. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(121) : Targeted, other(2) Gene trapped(119) |
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930596D02Rik |
T |
C |
14: 35,532,134 (GRCm39) |
E147G |
probably damaging |
Het |
| Agrn |
G |
A |
4: 156,257,094 (GRCm39) |
Q1217* |
probably null |
Het |
| Ankrd13c |
G |
C |
3: 157,653,313 (GRCm39) |
K50N |
probably benign |
Het |
| Anks3 |
C |
T |
16: 4,775,565 (GRCm39) |
S144N |
probably damaging |
Het |
| Apob |
A |
T |
12: 8,059,054 (GRCm39) |
D2512V |
probably damaging |
Het |
| Arhgap45 |
A |
G |
10: 79,863,694 (GRCm39) |
K815E |
probably damaging |
Het |
| Atr |
T |
A |
9: 95,747,098 (GRCm39) |
C127S |
probably benign |
Het |
| B4galnt4 |
A |
G |
7: 140,648,575 (GRCm39) |
D697G |
probably damaging |
Het |
| C2cd3 |
C |
T |
7: 100,029,249 (GRCm39) |
L134F |
probably damaging |
Het |
| Celsr2 |
C |
T |
3: 108,308,915 (GRCm39) |
G1697D |
probably damaging |
Het |
| Cep170 |
A |
G |
1: 176,583,821 (GRCm39) |
S88P |
possibly damaging |
Het |
| Cnot1 |
A |
G |
8: 96,455,874 (GRCm39) |
V1961A |
probably damaging |
Het |
| Cntnap4 |
A |
G |
8: 113,568,349 (GRCm39) |
N795S |
probably damaging |
Het |
| Cog2 |
T |
A |
8: 125,260,125 (GRCm39) |
V256D |
possibly damaging |
Het |
| Col14a1 |
A |
G |
15: 55,382,545 (GRCm39) |
Y515C |
|
Het |
| Cox7a1 |
A |
G |
7: 29,884,583 (GRCm39) |
Q30R |
probably damaging |
Het |
| Cs |
T |
C |
10: 128,196,885 (GRCm39) |
S427P |
probably damaging |
Het |
| Dbr1 |
T |
A |
9: 99,464,523 (GRCm39) |
C101S |
|
Het |
| Dhcr7 |
C |
A |
7: 143,401,212 (GRCm39) |
Y461* |
probably null |
Het |
| Dis3l2 |
T |
A |
1: 86,974,784 (GRCm39) |
M691K |
probably benign |
Het |
| Dnah17 |
T |
C |
11: 117,979,804 (GRCm39) |
D1751G |
probably damaging |
Het |
| Dock10 |
A |
T |
1: 80,481,389 (GRCm39) |
I536K |
|
Het |
| Dok6 |
G |
T |
18: 89,491,988 (GRCm39) |
F196L |
possibly damaging |
Het |
| Epx |
C |
T |
11: 87,755,651 (GRCm39) |
D678N |
probably damaging |
Het |
| Fcrlb |
G |
C |
1: 170,739,735 (GRCm39) |
P56A |
probably benign |
Het |
| Flrt3 |
T |
C |
2: 140,502,816 (GRCm39) |
R271G |
possibly damaging |
Het |
| Galnt15 |
T |
A |
14: 31,774,301 (GRCm39) |
L479Q |
probably damaging |
Het |
| Gfy |
G |
A |
7: 44,827,785 (GRCm39) |
L104F |
probably benign |
Het |
| Gltp |
C |
T |
5: 114,814,382 (GRCm39) |
M80I |
probably benign |
Het |
| Gm21560 |
G |
A |
14: 6,218,250 (GRCm38) |
T76I |
probably benign |
Het |
| Gm5150 |
A |
G |
3: 16,044,829 (GRCm39) |
I132T |
probably benign |
Het |
| Hdac9 |
T |
C |
12: 34,439,389 (GRCm39) |
H437R |
probably damaging |
Het |
| Hpgd |
C |
A |
8: 56,751,419 (GRCm39) |
F82L |
|
Het |
| Ifi207 |
GAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGACTATTGGATGGTGTTGATAGAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATACAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGAT |
GAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGACTATTGGATGGTGTTGATAGAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATACAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGAT |
1: 173,556,561 (GRCm39) |
|
probably benign |
Het |
| Ilrun |
A |
T |
17: 28,012,913 (GRCm39) |
F95I |
probably damaging |
Het |
| Itgb5 |
C |
T |
16: 33,696,295 (GRCm39) |
T162I |
probably damaging |
Het |
| Jakmip3 |
G |
A |
7: 138,625,118 (GRCm39) |
|
probably null |
Het |
| Kctd1 |
A |
T |
18: 15,196,611 (GRCm39) |
M4K |
unknown |
Het |
| Krt87 |
G |
C |
15: 101,389,048 (GRCm39) |
P95A |
probably benign |
Het |
| Man1a |
A |
T |
10: 53,796,158 (GRCm39) |
H511Q |
probably damaging |
Het |
| Megf8 |
A |
G |
7: 25,043,194 (GRCm39) |
D1372G |
possibly damaging |
Het |
| Mrgprd |
A |
G |
7: 144,875,189 (GRCm39) |
D20G |
probably benign |
Het |
| Mrpl54 |
C |
T |
10: 81,101,528 (GRCm39) |
G78S |
probably damaging |
Het |
| Myl1 |
T |
A |
1: 66,969,448 (GRCm39) |
E61D |
probably benign |
Het |
| Myo7a |
G |
T |
7: 97,712,937 (GRCm39) |
H1679Q |
probably benign |
Het |
| Naca |
A |
G |
10: 127,878,226 (GRCm39) |
E1086G |
unknown |
Het |
| Nagpa |
C |
G |
16: 5,017,829 (GRCm39) |
D258H |
probably damaging |
Het |
| Nicn1 |
C |
T |
9: 108,171,708 (GRCm39) |
R163C |
possibly damaging |
Het |
| Nr2f6 |
G |
A |
8: 71,827,171 (GRCm39) |
L377F |
probably damaging |
Het |
| Ntsr1 |
G |
A |
2: 180,183,274 (GRCm39) |
R328H |
probably damaging |
Het |
| Nup93 |
G |
A |
8: 95,033,267 (GRCm39) |
S592N |
probably damaging |
Het |
| Or10a2 |
A |
T |
7: 106,673,164 (GRCm39) |
N43I |
probably damaging |
Het |
| Or4k40 |
T |
A |
2: 111,251,137 (GRCm39) |
H53L |
probably benign |
Het |
| Or8g36 |
T |
C |
9: 39,422,497 (GRCm39) |
D173G |
probably benign |
Het |
| Pard3 |
T |
C |
8: 128,136,153 (GRCm39) |
V842A |
possibly damaging |
Het |
| Phospho2 |
T |
A |
2: 69,626,295 (GRCm39) |
N150K |
probably damaging |
Het |
| Piwil1 |
T |
C |
5: 128,831,051 (GRCm39) |
S791P |
probably damaging |
Het |
| Pkhd1 |
A |
G |
1: 20,462,437 (GRCm39) |
V2039A |
possibly damaging |
Het |
| Ppp1r3c |
A |
G |
19: 36,711,404 (GRCm39) |
I122T |
probably benign |
Het |
| Prrc2c |
A |
G |
1: 162,519,959 (GRCm39) |
Y2131H |
possibly damaging |
Het |
| Qtrt2 |
T |
C |
16: 43,683,540 (GRCm39) |
M311V |
possibly damaging |
Het |
| Rbbp4 |
T |
C |
4: 129,212,243 (GRCm39) |
D346G |
probably damaging |
Het |
| Slc13a5 |
A |
G |
11: 72,138,578 (GRCm39) |
I455T |
probably damaging |
Het |
| Slc28a3 |
A |
T |
13: 58,717,187 (GRCm39) |
Y366* |
probably null |
Het |
| Srgap1 |
T |
A |
10: 121,705,746 (GRCm39) |
Q226L |
probably benign |
Het |
| Syt17 |
A |
G |
7: 118,007,379 (GRCm39) |
V362A |
probably damaging |
Het |
| Tas2r117 |
T |
C |
6: 132,780,374 (GRCm39) |
S171P |
probably benign |
Het |
| Tfap2b |
A |
T |
1: 19,289,468 (GRCm39) |
I198F |
probably damaging |
Het |
| Tg |
A |
T |
15: 66,555,587 (GRCm39) |
I760F |
possibly damaging |
Het |
| Tmem123 |
T |
C |
9: 7,790,984 (GRCm39) |
V95A |
possibly damaging |
Het |
| Tmem198b |
C |
A |
10: 128,638,386 (GRCm39) |
G59V |
probably damaging |
Het |
| Tmem30c |
T |
G |
16: 57,096,585 (GRCm39) |
I179L |
probably benign |
Het |
| Tmprss2 |
A |
T |
16: 97,369,702 (GRCm39) |
D357E |
probably benign |
Het |
| Tns3 |
G |
A |
11: 8,401,142 (GRCm39) |
T1052M |
possibly damaging |
Het |
| Trex1 |
A |
T |
9: 108,887,632 (GRCm39) |
C120S |
probably damaging |
Het |
| Ttc8 |
A |
G |
12: 98,886,965 (GRCm39) |
S13G |
possibly damaging |
Het |
| Ttll7 |
T |
C |
3: 146,621,487 (GRCm39) |
I362T |
probably damaging |
Het |
| Usp34 |
A |
T |
11: 23,314,364 (GRCm39) |
T769S |
|
Het |
| Vmn1r185 |
G |
T |
7: 26,311,439 (GRCm39) |
T22K |
probably damaging |
Het |
| Vmn1r39 |
T |
G |
6: 66,781,578 (GRCm39) |
M247L |
probably benign |
Het |
| Vmn2r96 |
A |
G |
17: 18,803,257 (GRCm39) |
D389G |
probably benign |
Het |
| Xirp1 |
C |
T |
9: 119,846,379 (GRCm39) |
V835I |
probably benign |
Het |
| Ylpm1 |
T |
G |
12: 85,044,036 (GRCm39) |
I258S |
unknown |
Het |
| Zfp971 |
A |
T |
2: 177,675,417 (GRCm39) |
S339C |
probably damaging |
Het |
|
| Other mutations in Kirrel1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01310:Kirrel1
|
APN |
3 |
86,997,182 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL01865:Kirrel1
|
APN |
3 |
86,993,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01875:Kirrel1
|
APN |
3 |
87,003,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02337:Kirrel1
|
APN |
3 |
86,996,519 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL02724:Kirrel1
|
APN |
3 |
86,997,780 (GRCm39) |
nonsense |
probably null |
|
|
IGL02825:Kirrel1
|
APN |
3 |
86,996,595 (GRCm39) |
splice site |
probably benign |
|
|
IGL02826:Kirrel1
|
APN |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Kirrel1
|
APN |
3 |
86,990,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
D4043:Kirrel1
|
UTSW |
3 |
86,990,510 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0360:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0364:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0421:Kirrel1
|
UTSW |
3 |
86,990,914 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0503:Kirrel1
|
UTSW |
3 |
87,005,109 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1112:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1116:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1144:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1190:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1226:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1501:Kirrel1
|
UTSW |
3 |
86,997,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1538:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1546:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1628:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1630:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1631:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1664:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1671:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1695:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1769:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1807:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1808:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1840:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1995:Kirrel1
|
UTSW |
3 |
87,003,093 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2014:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2086:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2108:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2354:Kirrel1
|
UTSW |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2407:Kirrel1
|
UTSW |
3 |
86,992,150 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2904:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2905:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2958:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2959:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2960:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2961:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3026:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3028:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3034:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R3149:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3195:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3196:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3499:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3699:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3720:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3721:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3788:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3793:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3877:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3901:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3910:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3911:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3912:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3913:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3930:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3931:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4022:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4067:Kirrel1
|
UTSW |
3 |
86,995,774 (GRCm39) |
nonsense |
probably null |
|
|
R4077:Kirrel1
|
UTSW |
3 |
86,992,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4198:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4328:Kirrel1
|
UTSW |
3 |
86,992,081 (GRCm39) |
intron |
probably benign |
|
|
R4355:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4363:Kirrel1
|
UTSW |
3 |
86,997,792 (GRCm39) |
nonsense |
probably null |
|
|
R4378:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4386:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4460:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4468:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4469:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4650:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4652:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4734:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4748:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4749:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R5304:Kirrel1
|
UTSW |
3 |
86,996,902 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5534:Kirrel1
|
UTSW |
3 |
86,997,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5604:Kirrel1
|
UTSW |
3 |
86,996,462 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7199:Kirrel1
|
UTSW |
3 |
86,990,695 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7221:Kirrel1
|
UTSW |
3 |
86,993,704 (GRCm39) |
nonsense |
probably null |
|
|
R7284:Kirrel1
|
UTSW |
3 |
86,990,694 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7332:Kirrel1
|
UTSW |
3 |
86,995,705 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7369:Kirrel1
|
UTSW |
3 |
87,048,391 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7371:Kirrel1
|
UTSW |
3 |
86,995,729 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7508:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7566:Kirrel1
|
UTSW |
3 |
86,995,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7567:Kirrel1
|
UTSW |
3 |
87,002,988 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7621:Kirrel1
|
UTSW |
3 |
86,995,528 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8030:Kirrel1
|
UTSW |
3 |
87,005,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8141:Kirrel1
|
UTSW |
3 |
86,993,735 (GRCm39) |
nonsense |
probably null |
|
|
R8261:Kirrel1
|
UTSW |
3 |
86,995,309 (GRCm39) |
intron |
probably benign |
|
|
R8477:Kirrel1
|
UTSW |
3 |
86,992,138 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8512:Kirrel1
|
UTSW |
3 |
86,995,534 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8954:Kirrel1
|
UTSW |
3 |
86,997,173 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8987:Kirrel1
|
UTSW |
3 |
86,992,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kirrel1
|
UTSW |
3 |
86,992,442 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9146:Kirrel1
|
UTSW |
3 |
87,003,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Kirrel1
|
UTSW |
3 |
87,005,123 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9527:Kirrel1
|
UTSW |
3 |
86,996,912 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Kirrel1
|
UTSW |
3 |
86,991,182 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCCCTAGTTGATGATGAAGTTCATG -3'
(R):5'- TCTGCTGTGAGGAGAAGCTG -3'
Sequencing Primer
(F):5'- ATGAAGTTCATGTAAGGAGTTGC -3'
(R):5'- CTGTGAGGAGAAGCTGGGGAG -3'
|
| Posted On |
2022-09-12 |
Incidental Mutation