Incidental Mutation 'R9629:Srgap1'
| ID |
725368 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Srgap1
|
| Ensembl Gene |
ENSMUSG00000020121 |
| Gene Name |
SLIT-ROBO Rho GTPase activating protein 1 |
| Synonyms |
Arhgap13, 4930572H05Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.220)
|
| Stock # |
R9629 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
121616896-121883220 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 121705746 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Leucine
at position 226
(Q226L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000020322
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000020322]
[ENSMUST00000081688]
|
| AlphaFold |
Q91Z69 |
| PDB Structure |
Crystal structure of srGAP1 SH3 domain in the slit-robo signaling pathway [X-RAY DIFFRACTION]
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000020322
AA Change: Q226L
PolyPhen 2
Score 0.056 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000020322
Gene: ENSMUSG00000020121
AA Change: Q226L
| Domain | Start | End | E-Value | Type |
|---|
|
FCH
|
22 |
121 |
3.81e-16 |
SMART |
|
low complexity region
|
173 |
193 |
N/A |
INTRINSIC |
|
coiled coil region
|
352 |
382 |
N/A |
INTRINSIC |
|
low complexity region
|
405 |
418 |
N/A |
INTRINSIC |
|
RhoGAP
|
494 |
668 |
1.27e-64 |
SMART |
|
SH3
|
723 |
778 |
1.57e-14 |
SMART |
|
low complexity region
|
826 |
840 |
N/A |
INTRINSIC |
|
low complexity region
|
1004 |
1014 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000081688
AA Change: Q226L
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000080389
Gene: ENSMUSG00000020121
AA Change: Q226L
| Domain | Start | End | E-Value | Type |
|---|
|
FCH
|
22 |
121 |
3.81e-16 |
SMART |
|
low complexity region
|
173 |
193 |
N/A |
INTRINSIC |
|
coiled coil region
|
352 |
382 |
N/A |
INTRINSIC |
|
low complexity region
|
405 |
418 |
N/A |
INTRINSIC |
|
RhoGAP
|
517 |
691 |
1.27e-64 |
SMART |
|
SH3
|
746 |
801 |
1.57e-14 |
SMART |
|
low complexity region
|
849 |
863 |
N/A |
INTRINSIC |
|
low complexity region
|
1027 |
1037 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42. [provided by RefSeq, Sep 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930596D02Rik |
T |
C |
14: 35,532,134 (GRCm39) |
E147G |
probably damaging |
Het |
| Agrn |
G |
A |
4: 156,257,094 (GRCm39) |
Q1217* |
probably null |
Het |
| Ankrd13c |
G |
C |
3: 157,653,313 (GRCm39) |
K50N |
probably benign |
Het |
| Anks3 |
C |
T |
16: 4,775,565 (GRCm39) |
S144N |
probably damaging |
Het |
| Apob |
A |
T |
12: 8,059,054 (GRCm39) |
D2512V |
probably damaging |
Het |
| Arhgap45 |
A |
G |
10: 79,863,694 (GRCm39) |
K815E |
probably damaging |
Het |
| Atr |
T |
A |
9: 95,747,098 (GRCm39) |
C127S |
probably benign |
Het |
| B4galnt4 |
A |
G |
7: 140,648,575 (GRCm39) |
D697G |
probably damaging |
Het |
| C2cd3 |
C |
T |
7: 100,029,249 (GRCm39) |
L134F |
probably damaging |
Het |
| Celsr2 |
C |
T |
3: 108,308,915 (GRCm39) |
G1697D |
probably damaging |
Het |
| Cep170 |
A |
G |
1: 176,583,821 (GRCm39) |
S88P |
possibly damaging |
Het |
| Cnot1 |
A |
G |
8: 96,455,874 (GRCm39) |
V1961A |
probably damaging |
Het |
| Cntnap4 |
A |
G |
8: 113,568,349 (GRCm39) |
N795S |
probably damaging |
Het |
| Cog2 |
T |
A |
8: 125,260,125 (GRCm39) |
V256D |
possibly damaging |
Het |
| Col14a1 |
A |
G |
15: 55,382,545 (GRCm39) |
Y515C |
|
Het |
| Cox7a1 |
A |
G |
7: 29,884,583 (GRCm39) |
Q30R |
probably damaging |
Het |
| Cs |
T |
C |
10: 128,196,885 (GRCm39) |
S427P |
probably damaging |
Het |
| Dbr1 |
T |
A |
9: 99,464,523 (GRCm39) |
C101S |
|
Het |
| Dhcr7 |
C |
A |
7: 143,401,212 (GRCm39) |
Y461* |
probably null |
Het |
| Dis3l2 |
T |
A |
1: 86,974,784 (GRCm39) |
M691K |
probably benign |
Het |
| Dnah17 |
T |
C |
11: 117,979,804 (GRCm39) |
D1751G |
probably damaging |
Het |
| Dock10 |
A |
T |
1: 80,481,389 (GRCm39) |
I536K |
|
Het |
| Dok6 |
G |
T |
18: 89,491,988 (GRCm39) |
F196L |
possibly damaging |
Het |
| Epx |
C |
T |
11: 87,755,651 (GRCm39) |
D678N |
probably damaging |
Het |
| Fcrlb |
G |
C |
1: 170,739,735 (GRCm39) |
P56A |
probably benign |
Het |
| Flrt3 |
T |
C |
2: 140,502,816 (GRCm39) |
R271G |
possibly damaging |
Het |
| Galnt15 |
T |
A |
14: 31,774,301 (GRCm39) |
L479Q |
probably damaging |
Het |
| Gfy |
G |
A |
7: 44,827,785 (GRCm39) |
L104F |
probably benign |
Het |
| Gltp |
C |
T |
5: 114,814,382 (GRCm39) |
M80I |
probably benign |
Het |
| Gm21560 |
G |
A |
14: 6,218,250 (GRCm38) |
T76I |
probably benign |
Het |
| Gm5150 |
A |
G |
3: 16,044,829 (GRCm39) |
I132T |
probably benign |
Het |
| Hdac9 |
T |
C |
12: 34,439,389 (GRCm39) |
H437R |
probably damaging |
Het |
| Hpgd |
C |
A |
8: 56,751,419 (GRCm39) |
F82L |
|
Het |
| Ifi207 |
GAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGACTATTGGATGGTGTTGATAGAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATACAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGAT |
GAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGACTATTGGATGGTGTTGATAGAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATACAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGAT |
1: 173,556,561 (GRCm39) |
|
probably benign |
Het |
| Ilrun |
A |
T |
17: 28,012,913 (GRCm39) |
F95I |
probably damaging |
Het |
| Itgb5 |
C |
T |
16: 33,696,295 (GRCm39) |
T162I |
probably damaging |
Het |
| Jakmip3 |
G |
A |
7: 138,625,118 (GRCm39) |
|
probably null |
Het |
| Kctd1 |
A |
T |
18: 15,196,611 (GRCm39) |
M4K |
unknown |
Het |
| Kirrel1 |
C |
A |
3: 87,003,025 (GRCm39) |
E123* |
probably null |
Het |
| Krt87 |
G |
C |
15: 101,389,048 (GRCm39) |
P95A |
probably benign |
Het |
| Man1a |
A |
T |
10: 53,796,158 (GRCm39) |
H511Q |
probably damaging |
Het |
| Megf8 |
A |
G |
7: 25,043,194 (GRCm39) |
D1372G |
possibly damaging |
Het |
| Mrgprd |
A |
G |
7: 144,875,189 (GRCm39) |
D20G |
probably benign |
Het |
| Mrpl54 |
C |
T |
10: 81,101,528 (GRCm39) |
G78S |
probably damaging |
Het |
| Myl1 |
T |
A |
1: 66,969,448 (GRCm39) |
E61D |
probably benign |
Het |
| Myo7a |
G |
T |
7: 97,712,937 (GRCm39) |
H1679Q |
probably benign |
Het |
| Naca |
A |
G |
10: 127,878,226 (GRCm39) |
E1086G |
unknown |
Het |
| Nagpa |
C |
G |
16: 5,017,829 (GRCm39) |
D258H |
probably damaging |
Het |
| Nicn1 |
C |
T |
9: 108,171,708 (GRCm39) |
R163C |
possibly damaging |
Het |
| Nr2f6 |
G |
A |
8: 71,827,171 (GRCm39) |
L377F |
probably damaging |
Het |
| Ntsr1 |
G |
A |
2: 180,183,274 (GRCm39) |
R328H |
probably damaging |
Het |
| Nup93 |
G |
A |
8: 95,033,267 (GRCm39) |
S592N |
probably damaging |
Het |
| Or10a2 |
A |
T |
7: 106,673,164 (GRCm39) |
N43I |
probably damaging |
Het |
| Or4k40 |
T |
A |
2: 111,251,137 (GRCm39) |
H53L |
probably benign |
Het |
| Or8g36 |
T |
C |
9: 39,422,497 (GRCm39) |
D173G |
probably benign |
Het |
| Pard3 |
T |
C |
8: 128,136,153 (GRCm39) |
V842A |
possibly damaging |
Het |
| Phospho2 |
T |
A |
2: 69,626,295 (GRCm39) |
N150K |
probably damaging |
Het |
| Piwil1 |
T |
C |
5: 128,831,051 (GRCm39) |
S791P |
probably damaging |
Het |
| Pkhd1 |
A |
G |
1: 20,462,437 (GRCm39) |
V2039A |
possibly damaging |
Het |
| Ppp1r3c |
A |
G |
19: 36,711,404 (GRCm39) |
I122T |
probably benign |
Het |
| Prrc2c |
A |
G |
1: 162,519,959 (GRCm39) |
Y2131H |
possibly damaging |
Het |
| Qtrt2 |
T |
C |
16: 43,683,540 (GRCm39) |
M311V |
possibly damaging |
Het |
| Rbbp4 |
T |
C |
4: 129,212,243 (GRCm39) |
D346G |
probably damaging |
Het |
| Slc13a5 |
A |
G |
11: 72,138,578 (GRCm39) |
I455T |
probably damaging |
Het |
| Slc28a3 |
A |
T |
13: 58,717,187 (GRCm39) |
Y366* |
probably null |
Het |
| Syt17 |
A |
G |
7: 118,007,379 (GRCm39) |
V362A |
probably damaging |
Het |
| Tas2r117 |
T |
C |
6: 132,780,374 (GRCm39) |
S171P |
probably benign |
Het |
| Tfap2b |
A |
T |
1: 19,289,468 (GRCm39) |
I198F |
probably damaging |
Het |
| Tg |
A |
T |
15: 66,555,587 (GRCm39) |
I760F |
possibly damaging |
Het |
| Tmem123 |
T |
C |
9: 7,790,984 (GRCm39) |
V95A |
possibly damaging |
Het |
| Tmem198b |
C |
A |
10: 128,638,386 (GRCm39) |
G59V |
probably damaging |
Het |
| Tmem30c |
T |
G |
16: 57,096,585 (GRCm39) |
I179L |
probably benign |
Het |
| Tmprss2 |
A |
T |
16: 97,369,702 (GRCm39) |
D357E |
probably benign |
Het |
| Tns3 |
G |
A |
11: 8,401,142 (GRCm39) |
T1052M |
possibly damaging |
Het |
| Trex1 |
A |
T |
9: 108,887,632 (GRCm39) |
C120S |
probably damaging |
Het |
| Ttc8 |
A |
G |
12: 98,886,965 (GRCm39) |
S13G |
possibly damaging |
Het |
| Ttll7 |
T |
C |
3: 146,621,487 (GRCm39) |
I362T |
probably damaging |
Het |
| Usp34 |
A |
T |
11: 23,314,364 (GRCm39) |
T769S |
|
Het |
| Vmn1r185 |
G |
T |
7: 26,311,439 (GRCm39) |
T22K |
probably damaging |
Het |
| Vmn1r39 |
T |
G |
6: 66,781,578 (GRCm39) |
M247L |
probably benign |
Het |
| Vmn2r96 |
A |
G |
17: 18,803,257 (GRCm39) |
D389G |
probably benign |
Het |
| Xirp1 |
C |
T |
9: 119,846,379 (GRCm39) |
V835I |
probably benign |
Het |
| Ylpm1 |
T |
G |
12: 85,044,036 (GRCm39) |
I258S |
unknown |
Het |
| Zfp971 |
A |
T |
2: 177,675,417 (GRCm39) |
S339C |
probably damaging |
Het |
|
| Other mutations in Srgap1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01964:Srgap1
|
APN |
10 |
121,640,871 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02106:Srgap1
|
APN |
10 |
121,621,598 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02927:Srgap1
|
APN |
10 |
121,691,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03088:Srgap1
|
APN |
10 |
121,661,598 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03208:Srgap1
|
APN |
10 |
121,628,171 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL03251:Srgap1
|
APN |
10 |
121,640,826 (GRCm39) |
splice site |
probably null |
|
|
PIT1430001:Srgap1
|
UTSW |
10 |
121,732,658 (GRCm39) |
splice site |
probably benign |
|
|
R0052:Srgap1
|
UTSW |
10 |
121,636,732 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0052:Srgap1
|
UTSW |
10 |
121,636,732 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0356:Srgap1
|
UTSW |
10 |
121,691,441 (GRCm39) |
splice site |
probably null |
|
|
R0361:Srgap1
|
UTSW |
10 |
121,883,097 (GRCm39) |
start codon destroyed |
probably null |
0.89 |
|
R0365:Srgap1
|
UTSW |
10 |
121,621,610 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0675:Srgap1
|
UTSW |
10 |
121,628,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0801:Srgap1
|
UTSW |
10 |
121,643,780 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0815:Srgap1
|
UTSW |
10 |
121,621,379 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1034:Srgap1
|
UTSW |
10 |
121,621,350 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R1160:Srgap1
|
UTSW |
10 |
121,691,382 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1454:Srgap1
|
UTSW |
10 |
121,732,643 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1624:Srgap1
|
UTSW |
10 |
121,691,278 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1628:Srgap1
|
UTSW |
10 |
121,706,244 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1816:Srgap1
|
UTSW |
10 |
121,761,876 (GRCm39) |
nonsense |
probably null |
|
|
R1933:Srgap1
|
UTSW |
10 |
121,761,808 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2034:Srgap1
|
UTSW |
10 |
121,628,651 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2211:Srgap1
|
UTSW |
10 |
121,689,645 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2295:Srgap1
|
UTSW |
10 |
121,630,665 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2368:Srgap1
|
UTSW |
10 |
121,665,194 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3796:Srgap1
|
UTSW |
10 |
121,883,037 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4083:Srgap1
|
UTSW |
10 |
121,621,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4172:Srgap1
|
UTSW |
10 |
121,691,268 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4322:Srgap1
|
UTSW |
10 |
121,705,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4401:Srgap1
|
UTSW |
10 |
121,640,826 (GRCm39) |
splice site |
probably null |
|
|
R4513:Srgap1
|
UTSW |
10 |
121,706,231 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4698:Srgap1
|
UTSW |
10 |
121,628,392 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4776:Srgap1
|
UTSW |
10 |
121,628,256 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4951:Srgap1
|
UTSW |
10 |
121,621,457 (GRCm39) |
missense |
probably benign |
0.20 |
|
R5116:Srgap1
|
UTSW |
10 |
121,628,284 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5232:Srgap1
|
UTSW |
10 |
121,676,816 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5237:Srgap1
|
UTSW |
10 |
121,643,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5335:Srgap1
|
UTSW |
10 |
121,621,282 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R5402:Srgap1
|
UTSW |
10 |
121,621,665 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5432:Srgap1
|
UTSW |
10 |
121,705,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5456:Srgap1
|
UTSW |
10 |
121,705,716 (GRCm39) |
missense |
probably benign |
0.45 |
|
R5669:Srgap1
|
UTSW |
10 |
121,640,755 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5682:Srgap1
|
UTSW |
10 |
121,640,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5687:Srgap1
|
UTSW |
10 |
121,661,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5773:Srgap1
|
UTSW |
10 |
121,732,614 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5832:Srgap1
|
UTSW |
10 |
121,676,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6028:Srgap1
|
UTSW |
10 |
121,664,635 (GRCm39) |
missense |
probably null |
|
|
R6240:Srgap1
|
UTSW |
10 |
121,883,061 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6336:Srgap1
|
UTSW |
10 |
121,761,846 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6435:Srgap1
|
UTSW |
10 |
121,636,732 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6597:Srgap1
|
UTSW |
10 |
121,628,276 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6798:Srgap1
|
UTSW |
10 |
121,761,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6807:Srgap1
|
UTSW |
10 |
121,664,631 (GRCm39) |
splice site |
probably null |
|
|
R6897:Srgap1
|
UTSW |
10 |
121,621,523 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7057:Srgap1
|
UTSW |
10 |
121,640,858 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7196:Srgap1
|
UTSW |
10 |
121,676,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7247:Srgap1
|
UTSW |
10 |
121,705,695 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7404:Srgap1
|
UTSW |
10 |
121,621,650 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7467:Srgap1
|
UTSW |
10 |
121,691,344 (GRCm39) |
nonsense |
probably null |
|
|
R7792:Srgap1
|
UTSW |
10 |
121,761,872 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7846:Srgap1
|
UTSW |
10 |
121,621,397 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7896:Srgap1
|
UTSW |
10 |
121,689,458 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7912:Srgap1
|
UTSW |
10 |
121,689,458 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R8127:Srgap1
|
UTSW |
10 |
121,691,271 (GRCm39) |
missense |
probably null |
0.04 |
|
R8233:Srgap1
|
UTSW |
10 |
121,661,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8248:Srgap1
|
UTSW |
10 |
121,640,722 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8362:Srgap1
|
UTSW |
10 |
121,691,383 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8885:Srgap1
|
UTSW |
10 |
121,761,545 (GRCm39) |
intron |
probably benign |
|
|
R9074:Srgap1
|
UTSW |
10 |
121,628,257 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9134:Srgap1
|
UTSW |
10 |
121,883,127 (GRCm39) |
start gained |
probably benign |
|
|
R9338:Srgap1
|
UTSW |
10 |
121,689,458 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R9437:Srgap1
|
UTSW |
10 |
121,636,777 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9747:Srgap1
|
UTSW |
10 |
121,761,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9747:Srgap1
|
UTSW |
10 |
121,628,579 (GRCm39) |
missense |
probably benign |
|
|
X0063:Srgap1
|
UTSW |
10 |
121,621,317 (GRCm39) |
missense |
probably damaging |
0.97 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGAGCGACTCCAACGAATGC -3'
(R):5'- TTTTCAGAGCCAGGGAACTTG -3'
Sequencing Primer
(F):5'- AACGAATGCTGGCACTTTCC -3'
(R):5'- CGTCGAGATGACTTTGCT -3'
|
| Posted On |
2022-09-12 |
Incidental Mutation