Incidental Mutation 'R9631:Ttc3'
| ID |
725531 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ttc3
|
| Ensembl Gene |
ENSMUSG00000040785 |
| Gene Name |
tetratricopeptide repeat domain 3 |
| Synonyms |
D16Ium21e, TPRD, 2610202A04Rik, D16Ium21 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.574)
|
| Stock # |
R9631 (G1)
|
| Quality Score |
152.008 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
94171479-94270081 bp(+) (GRCm39) |
| Type of Mutation |
intron |
| DNA Base Change (assembly) |
G to T
at 94171581 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000155972
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000113905]
[ENSMUST00000113906]
[ENSMUST00000113910]
[ENSMUST00000113914]
[ENSMUST00000113917]
[ENSMUST00000117648]
[ENSMUST00000119131]
[ENSMUST00000122895]
[ENSMUST00000138514]
[ENSMUST00000139513]
[ENSMUST00000141856]
[ENSMUST00000143145]
[ENSMUST00000145432]
[ENSMUST00000145883]
[ENSMUST00000147046]
[ENSMUST00000147352]
[ENSMUST00000149885]
[ENSMUST00000150097]
[ENSMUST00000150346]
[ENSMUST00000151770]
[ENSMUST00000152117]
[ENSMUST00000153062]
[ENSMUST00000153988]
[ENSMUST00000154243]
[ENSMUST00000155692]
[ENSMUST00000231569]
[ENSMUST00000232294]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113905
|
| SMART Domains |
Protein: ENSMUSP00000109538
Gene: ENSMUSG00000022940
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PIG-P
|
10 |
125 |
7.6e-45 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113906
|
| SMART Domains |
Protein: ENSMUSP00000109539
Gene: ENSMUSG00000022940
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PIG-P
|
10 |
125 |
7.6e-45 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113910
|
| SMART Domains |
Protein: ENSMUSP00000109543
Gene: ENSMUSG00000022940
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PIG-P
|
39 |
154 |
1.5e-44 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113914
|
| SMART Domains |
Protein: ENSMUSP00000109547
Gene: ENSMUSG00000022940
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
19 |
N/A |
INTRINSIC |
|
Pfam:PIG-P
|
84 |
197 |
1e-43 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113917
|
| SMART Domains |
Protein: ENSMUSP00000109550
Gene: ENSMUSG00000022940
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PIG-P
|
43 |
135 |
5.6e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117648
|
| SMART Domains |
Protein: ENSMUSP00000112801
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
TPR
|
231 |
264 |
3.61e-2 |
SMART |
|
TPR
|
265 |
298 |
3.32e-1 |
SMART |
|
Blast:TPR
|
300 |
332 |
2e-12 |
BLAST |
|
low complexity region
|
444 |
459 |
N/A |
INTRINSIC |
|
TPR
|
576 |
609 |
2.55e-2 |
SMART |
|
low complexity region
|
720 |
732 |
N/A |
INTRINSIC |
|
coiled coil region
|
765 |
796 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1032 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1050 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1190 |
N/A |
INTRINSIC |
|
low complexity region
|
1248 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1278 |
1291 |
N/A |
INTRINSIC |
|
coiled coil region
|
1472 |
1570 |
N/A |
INTRINSIC |
|
low complexity region
|
1876 |
1887 |
N/A |
INTRINSIC |
|
RING
|
1931 |
1970 |
7e-9 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000119131
|
| SMART Domains |
Protein: ENSMUSP00000113311
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TPR_11
|
229 |
285 |
1.1e-12 |
PFAM |
|
Pfam:TPR_1
|
232 |
264 |
2.1e-4 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122895
|
| SMART Domains |
Protein: ENSMUSP00000123037
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
TPR
|
213 |
246 |
3.61e-2 |
SMART |
|
TPR
|
247 |
280 |
3.32e-1 |
SMART |
|
Blast:TPR
|
282 |
314 |
3e-12 |
BLAST |
|
low complexity region
|
426 |
441 |
N/A |
INTRINSIC |
|
TPR
|
558 |
591 |
2.55e-2 |
SMART |
|
low complexity region
|
702 |
714 |
N/A |
INTRINSIC |
|
coiled coil region
|
747 |
778 |
N/A |
INTRINSIC |
|
low complexity region
|
1000 |
1014 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1032 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000127667
|
| SMART Domains |
Protein: ENSMUSP00000122425
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TPR_11
|
22 |
89 |
4.7e-16 |
PFAM |
|
Pfam:TPR_2
|
24 |
57 |
5.7e-4 |
PFAM |
|
Pfam:TPR_1
|
25 |
57 |
3.5e-5 |
PFAM |
|
Pfam:TPR_9
|
35 |
103 |
3.2e-6 |
PFAM |
|
Pfam:TPR_1
|
58 |
89 |
2.1e-4 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000138514
|
| SMART Domains |
Protein: ENSMUSP00000114477
Gene: ENSMUSG00000022940
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PIG-P
|
43 |
152 |
1.2e-42 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000139513
|
| SMART Domains |
Protein: ENSMUSP00000117881
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
22 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000141856
|
| SMART Domains |
Protein: ENSMUSP00000117369
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TPR_1
|
90 |
121 |
1e-6 |
PFAM |
|
Pfam:TPR_2
|
90 |
121 |
7.9e-6 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000143145
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145432
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145883
|
| SMART Domains |
Protein: ENSMUSP00000123442
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
42 |
64 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000147046
|
| SMART Domains |
Protein: ENSMUSP00000119265
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
43 |
58 |
N/A |
INTRINSIC |
|
Pfam:TPR_1
|
175 |
206 |
5.3e-6 |
PFAM |
|
low complexity region
|
319 |
331 |
N/A |
INTRINSIC |
|
low complexity region
|
359 |
382 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000147352
|
| SMART Domains |
Protein: ENSMUSP00000116097
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
TPR
|
213 |
246 |
3.61e-2 |
SMART |
|
TPR
|
247 |
280 |
3.32e-1 |
SMART |
|
Blast:TPR
|
282 |
314 |
3e-12 |
BLAST |
|
low complexity region
|
426 |
441 |
N/A |
INTRINSIC |
|
TPR
|
558 |
591 |
2.55e-2 |
SMART |
|
low complexity region
|
702 |
714 |
N/A |
INTRINSIC |
|
coiled coil region
|
747 |
778 |
N/A |
INTRINSIC |
|
low complexity region
|
1000 |
1014 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1032 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149885
|
| SMART Domains |
Protein: ENSMUSP00000122006
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TPR_2
|
1 |
31 |
3.5e-4 |
PFAM |
|
Pfam:TPR_11
|
1 |
58 |
7.8e-16 |
PFAM |
|
Pfam:TPR_1
|
2 |
31 |
1.8e-5 |
PFAM |
|
Pfam:TPR_9
|
9 |
58 |
2.5e-6 |
PFAM |
|
Pfam:TPR_17
|
20 |
53 |
4.2e-7 |
PFAM |
|
Pfam:TPR_1
|
32 |
58 |
2.5e-4 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150097
|
| SMART Domains |
Protein: ENSMUSP00000119035
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:TPR
|
1 |
22 |
1e-6 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150346
|
| SMART Domains |
Protein: ENSMUSP00000122726
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
43 |
58 |
N/A |
INTRINSIC |
|
Pfam:TPR_1
|
175 |
206 |
9.6e-6 |
PFAM |
|
low complexity region
|
319 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
364 |
395 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151770
|
| SMART Domains |
Protein: ENSMUSP00000121349
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
TPR
|
231 |
264 |
3.61e-2 |
SMART |
|
TPR
|
265 |
298 |
3.32e-1 |
SMART |
|
Blast:TPR
|
300 |
332 |
3e-12 |
BLAST |
|
low complexity region
|
444 |
459 |
N/A |
INTRINSIC |
|
TPR
|
576 |
609 |
2.55e-2 |
SMART |
|
low complexity region
|
720 |
732 |
N/A |
INTRINSIC |
|
coiled coil region
|
765 |
796 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1032 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1050 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152117
|
| SMART Domains |
Protein: ENSMUSP00000116896
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
43 |
58 |
N/A |
INTRINSIC |
|
SCOP:d1ihga1
|
69 |
201 |
6e-8 |
SMART |
|
Blast:TPR
|
175 |
208 |
1e-14 |
BLAST |
|
low complexity region
|
319 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
364 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
617 |
631 |
N/A |
INTRINSIC |
|
low complexity region
|
635 |
649 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000153062
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000153988
|
| SMART Domains |
Protein: ENSMUSP00000118763
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:TPR
|
1 |
22 |
3e-6 |
BLAST |
|
low complexity region
|
134 |
149 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000154243
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155692
|
| SMART Domains |
Protein: ENSMUSP00000122724
Gene: ENSMUSG00000040785
| Domain | Start | End | E-Value | Type |
|---|
|
TPR
|
250 |
283 |
3.61e-2 |
SMART |
|
TPR
|
284 |
317 |
3.32e-1 |
SMART |
|
Blast:TPR
|
319 |
351 |
3e-12 |
BLAST |
|
low complexity region
|
463 |
478 |
N/A |
INTRINSIC |
|
TPR
|
595 |
628 |
2.55e-2 |
SMART |
|
low complexity region
|
739 |
751 |
N/A |
INTRINSIC |
|
coiled coil region
|
784 |
815 |
N/A |
INTRINSIC |
|
low complexity region
|
1037 |
1051 |
N/A |
INTRINSIC |
|
low complexity region
|
1055 |
1069 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000231569
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000232294
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Atl3 |
A |
G |
19: 7,509,553 (GRCm39) |
N427S |
probably benign |
Het |
| Bcar3 |
T |
A |
3: 122,301,801 (GRCm39) |
D165E |
possibly damaging |
Het |
| Brap |
T |
C |
5: 121,822,435 (GRCm39) |
I437T |
probably benign |
Het |
| Bspry |
T |
C |
4: 62,400,955 (GRCm39) |
|
probably null |
Het |
| Camkv |
G |
T |
9: 107,822,990 (GRCm39) |
V77L |
probably benign |
Het |
| Capn15 |
A |
T |
17: 26,182,409 (GRCm39) |
D566E |
probably damaging |
Het |
| Ccar2 |
A |
G |
14: 70,389,344 (GRCm39) |
V76A |
probably damaging |
Het |
| Ccdc142 |
T |
C |
6: 83,084,142 (GRCm39) |
C516R |
probably benign |
Het |
| Ccdc92b |
T |
A |
11: 74,520,845 (GRCm39) |
V49E |
|
Het |
| Ccr7 |
A |
G |
11: 99,036,616 (GRCm39) |
V102A |
probably benign |
Het |
| Cdh23 |
A |
T |
10: 60,243,168 (GRCm39) |
V1069E |
possibly damaging |
Het |
| Cimip2c |
A |
G |
5: 30,639,529 (GRCm39) |
D152G |
|
Het |
| Clpb |
T |
G |
7: 101,434,605 (GRCm39) |
V467G |
possibly damaging |
Het |
| Crebzf |
T |
A |
7: 90,093,013 (GRCm39) |
L264Q |
probably damaging |
Het |
| Ctif |
A |
G |
18: 75,605,025 (GRCm39) |
F505L |
probably benign |
Het |
| Cyp2j5 |
A |
G |
4: 96,529,522 (GRCm39) |
I283T |
probably benign |
Het |
| Ddx39a |
C |
A |
8: 84,447,729 (GRCm39) |
H191Q |
possibly damaging |
Het |
| Dnajc9 |
A |
T |
14: 20,438,670 (GRCm39) |
|
probably null |
Het |
| Dock7 |
A |
G |
4: 98,854,560 (GRCm39) |
L1568P |
unknown |
Het |
| Dpp10 |
T |
C |
1: 123,269,432 (GRCm39) |
Y659C |
probably damaging |
Het |
| Eef1akmt3 |
A |
G |
10: 126,877,161 (GRCm39) |
F35L |
probably benign |
Het |
| Etl4 |
A |
T |
2: 20,666,749 (GRCm39) |
N52I |
probably benign |
Het |
| F5 |
T |
A |
1: 164,014,423 (GRCm39) |
C565S |
probably damaging |
Het |
| Fam170b |
T |
C |
14: 32,557,641 (GRCm39) |
S159P |
probably damaging |
Het |
| Fitm2 |
A |
G |
2: 163,311,757 (GRCm39) |
I152T |
probably damaging |
Het |
| Fn1 |
T |
C |
1: 71,625,387 (GRCm39) |
D2473G |
probably benign |
Het |
| Fzd2 |
C |
A |
11: 102,496,916 (GRCm39) |
D453E |
probably benign |
Het |
| Grm5 |
T |
C |
7: 87,624,560 (GRCm39) |
Y376H |
probably damaging |
Het |
| H2-Q6 |
T |
A |
17: 35,644,292 (GRCm39) |
H91Q |
probably benign |
Het |
| Hspa4 |
A |
T |
11: 53,160,582 (GRCm39) |
V498E |
possibly damaging |
Het |
| Igsf10 |
A |
T |
3: 59,237,904 (GRCm39) |
L759H |
probably damaging |
Het |
| Jph1 |
T |
C |
1: 17,161,607 (GRCm39) |
T352A |
probably damaging |
Het |
| Kit |
C |
T |
5: 75,767,689 (GRCm39) |
T24M |
possibly damaging |
Het |
| Krtap28-13 |
T |
G |
1: 83,038,897 (GRCm39) |
C61G |
unknown |
Het |
| Lgr5 |
T |
A |
10: 115,302,513 (GRCm39) |
I293F |
probably damaging |
Het |
| Lyzl4 |
GGACACACTGCAGAGGGAGTGGAGAGAAAGGGACCCACCAGTGCAAGACACACTGCAGAGGGAGTGGAGAGAAAGGGACCCACCAGTGCAGGACACACTGCAGAGG |
GGACACACTGCAGAGGGAGTGGAGAGAAAGGGACCCACCAGTGCAGGACACACTGCAGAGG |
9: 121,413,055 (GRCm39) |
|
probably null |
Het |
| Mccc1 |
C |
A |
3: 36,014,185 (GRCm39) |
E711* |
probably null |
Het |
| Mroh2b |
C |
T |
15: 4,946,556 (GRCm39) |
T452I |
probably damaging |
Het |
| Ms4a10 |
G |
A |
19: 10,944,451 (GRCm39) |
T111I |
probably damaging |
Het |
| Myh11 |
A |
T |
16: 14,025,441 (GRCm39) |
V1443E |
|
Het |
| Oc90 |
A |
G |
15: 65,769,629 (GRCm39) |
L76P |
probably damaging |
Het |
| Or10d3 |
G |
A |
9: 39,461,508 (GRCm39) |
R220* |
probably null |
Het |
| Or4c118 |
T |
C |
2: 88,975,522 (GRCm39) |
|
probably benign |
Het |
| Or4f57 |
A |
G |
2: 111,791,377 (GRCm39) |
F14L |
probably benign |
Het |
| Or56a42-ps1 |
A |
T |
7: 104,775,607 (GRCm39) |
I290N |
probably damaging |
Het |
| Or5b97 |
A |
G |
19: 12,878,502 (GRCm39) |
V214A |
possibly damaging |
Het |
| Or8b57 |
A |
G |
9: 40,004,223 (GRCm39) |
V13A |
probably damaging |
Het |
| Or8c10 |
G |
A |
9: 38,279,714 (GRCm39) |
V281M |
possibly damaging |
Het |
| Or8g52 |
A |
T |
9: 39,631,161 (GRCm39) |
T213S |
possibly damaging |
Het |
| Pgr |
C |
A |
9: 8,900,847 (GRCm39) |
Q127K |
probably benign |
Het |
| Qrich2 |
GCTGCACCTGGTTGCAACACACCAGGCTGAACTGCACCTGGTTGCAACACACCAGGCTGAACTGCACCTGGTTGCAACACACCAGGCTGAACTGCACCTGGTTG |
GCTGCACCTGGTTGCAACACACCAGGCTGAACTGCACCTGGTTGCAACACACCAGGCTGAACTGCACCTGGTTG |
11: 116,348,367 (GRCm39) |
|
probably benign |
Het |
| Rfc1 |
C |
T |
5: 65,429,851 (GRCm39) |
V852M |
probably damaging |
Het |
| Rin2 |
T |
A |
2: 145,718,437 (GRCm39) |
L639H |
probably damaging |
Het |
| Rpap2 |
T |
A |
5: 107,768,292 (GRCm39) |
W377R |
probably damaging |
Het |
| Senp7 |
T |
C |
16: 55,975,631 (GRCm39) |
S446P |
probably benign |
Het |
| Sipa1l1 |
A |
G |
12: 82,387,776 (GRCm39) |
M1V |
probably null |
Het |
| Slc25a36 |
A |
C |
9: 96,982,153 (GRCm39) |
S61A |
probably benign |
Het |
| Sptbn2 |
C |
T |
19: 4,788,218 (GRCm39) |
R1066W |
probably damaging |
Het |
| Tgm6 |
A |
G |
2: 129,977,810 (GRCm39) |
S50G |
probably benign |
Het |
| Thada |
T |
C |
17: 84,538,584 (GRCm39) |
S1475G |
probably benign |
Het |
| Tln1 |
G |
A |
4: 43,545,694 (GRCm39) |
A928V |
probably damaging |
Het |
| Trip11 |
G |
A |
12: 101,859,807 (GRCm39) |
L357F |
probably benign |
Het |
| Ttc38 |
T |
C |
15: 85,728,659 (GRCm39) |
S204P |
possibly damaging |
Het |
| Vmn1r237 |
A |
T |
17: 21,534,660 (GRCm39) |
I128F |
probably benign |
Het |
| Vmn2r50 |
A |
T |
7: 9,786,990 (GRCm39) |
L39* |
probably null |
Het |
| Vps4b |
A |
G |
1: 106,707,835 (GRCm39) |
V216A |
possibly damaging |
Het |
| Zfp217 |
T |
C |
2: 169,956,790 (GRCm39) |
N736S |
possibly damaging |
Het |
| Zfp985 |
A |
G |
4: 147,665,742 (GRCm39) |
E25G |
probably damaging |
Het |
| Zfr |
C |
T |
15: 12,154,628 (GRCm39) |
R604* |
probably null |
Het |
| Zscan18 |
A |
G |
7: 12,505,657 (GRCm39) |
S577P |
possibly damaging |
Het |
|
| Other mutations in Ttc3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00944:Ttc3
|
APN |
16 |
94,227,620 (GRCm39) |
splice site |
probably null |
|
|
IGL00979:Ttc3
|
APN |
16 |
94,257,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01520:Ttc3
|
APN |
16 |
94,191,066 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01663:Ttc3
|
APN |
16 |
94,210,590 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01720:Ttc3
|
APN |
16 |
94,186,228 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01736:Ttc3
|
APN |
16 |
94,243,386 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02045:Ttc3
|
APN |
16 |
94,210,540 (GRCm39) |
splice site |
probably benign |
|
|
IGL02203:Ttc3
|
APN |
16 |
94,219,457 (GRCm39) |
splice site |
probably benign |
|
|
IGL02327:Ttc3
|
APN |
16 |
94,248,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Ttc3
|
APN |
16 |
94,268,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02898:Ttc3
|
APN |
16 |
94,220,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4378001:Ttc3
|
UTSW |
16 |
94,211,765 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0064:Ttc3
|
UTSW |
16 |
94,223,106 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0098:Ttc3
|
UTSW |
16 |
94,191,124 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0112:Ttc3
|
UTSW |
16 |
94,186,181 (GRCm39) |
splice site |
probably benign |
|
|
R0135:Ttc3
|
UTSW |
16 |
94,263,127 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0480:Ttc3
|
UTSW |
16 |
94,232,863 (GRCm39) |
nonsense |
probably null |
|
|
R0513:Ttc3
|
UTSW |
16 |
94,227,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0532:Ttc3
|
UTSW |
16 |
94,188,189 (GRCm39) |
splice site |
probably benign |
|
|
R0607:Ttc3
|
UTSW |
16 |
94,257,644 (GRCm39) |
nonsense |
probably null |
|
|
R0742:Ttc3
|
UTSW |
16 |
94,260,739 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0905:Ttc3
|
UTSW |
16 |
94,257,648 (GRCm39) |
nonsense |
probably null |
|
|
R1118:Ttc3
|
UTSW |
16 |
94,217,127 (GRCm39) |
splice site |
probably benign |
|
|
R1355:Ttc3
|
UTSW |
16 |
94,219,496 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1370:Ttc3
|
UTSW |
16 |
94,219,496 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1486:Ttc3
|
UTSW |
16 |
94,248,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1598:Ttc3
|
UTSW |
16 |
94,223,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1641:Ttc3
|
UTSW |
16 |
94,244,176 (GRCm39) |
missense |
probably benign |
0.19 |
|
R2092:Ttc3
|
UTSW |
16 |
94,243,691 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2232:Ttc3
|
UTSW |
16 |
94,260,831 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2339:Ttc3
|
UTSW |
16 |
94,232,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2342:Ttc3
|
UTSW |
16 |
94,232,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2842:Ttc3
|
UTSW |
16 |
94,232,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3117:Ttc3
|
UTSW |
16 |
94,243,422 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4194:Ttc3
|
UTSW |
16 |
94,223,136 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4329:Ttc3
|
UTSW |
16 |
94,267,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4431:Ttc3
|
UTSW |
16 |
94,211,817 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4530:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4531:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4532:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4533:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4588:Ttc3
|
UTSW |
16 |
94,243,760 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4625:Ttc3
|
UTSW |
16 |
94,189,131 (GRCm39) |
nonsense |
probably null |
|
|
R4676:Ttc3
|
UTSW |
16 |
94,243,620 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4700:Ttc3
|
UTSW |
16 |
94,240,100 (GRCm39) |
splice site |
probably null |
|
|
R4856:Ttc3
|
UTSW |
16 |
94,191,142 (GRCm39) |
missense |
probably benign |
0.32 |
|
R4867:Ttc3
|
UTSW |
16 |
94,255,374 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4885:Ttc3
|
UTSW |
16 |
94,227,690 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4885:Ttc3
|
UTSW |
16 |
94,220,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4899:Ttc3
|
UTSW |
16 |
94,230,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4997:Ttc3
|
UTSW |
16 |
94,253,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5023:Ttc3
|
UTSW |
16 |
94,230,218 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5105:Ttc3
|
UTSW |
16 |
94,267,793 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5205:Ttc3
|
UTSW |
16 |
94,248,918 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5287:Ttc3
|
UTSW |
16 |
94,260,703 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5338:Ttc3
|
UTSW |
16 |
94,184,900 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5347:Ttc3
|
UTSW |
16 |
94,230,479 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5403:Ttc3
|
UTSW |
16 |
94,260,703 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5460:Ttc3
|
UTSW |
16 |
94,258,241 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5739:Ttc3
|
UTSW |
16 |
94,240,183 (GRCm39) |
nonsense |
probably null |
|
|
R6242:Ttc3
|
UTSW |
16 |
94,243,554 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6253:Ttc3
|
UTSW |
16 |
94,258,272 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6455:Ttc3
|
UTSW |
16 |
94,219,482 (GRCm39) |
start codon destroyed |
probably null |
0.83 |
|
R6559:Ttc3
|
UTSW |
16 |
94,223,208 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6564:Ttc3
|
UTSW |
16 |
94,243,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6932:Ttc3
|
UTSW |
16 |
94,244,312 (GRCm39) |
missense |
probably benign |
|
|
R7331:Ttc3
|
UTSW |
16 |
94,195,218 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7497:Ttc3
|
UTSW |
16 |
94,219,541 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7610:Ttc3
|
UTSW |
16 |
94,228,697 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7738:Ttc3
|
UTSW |
16 |
94,188,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7970:Ttc3
|
UTSW |
16 |
94,258,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8052:Ttc3
|
UTSW |
16 |
94,268,848 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8087:Ttc3
|
UTSW |
16 |
94,243,812 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8309:Ttc3
|
UTSW |
16 |
94,267,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8320:Ttc3
|
UTSW |
16 |
94,219,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8322:Ttc3
|
UTSW |
16 |
94,255,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8518:Ttc3
|
UTSW |
16 |
94,258,238 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8670:Ttc3
|
UTSW |
16 |
94,191,067 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Ttc3
|
UTSW |
16 |
94,232,829 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8868:Ttc3
|
UTSW |
16 |
94,252,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8873:Ttc3
|
UTSW |
16 |
94,243,842 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8940:Ttc3
|
UTSW |
16 |
94,230,358 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8993:Ttc3
|
UTSW |
16 |
94,228,667 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9068:Ttc3
|
UTSW |
16 |
94,204,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9119:Ttc3
|
UTSW |
16 |
94,192,950 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9124:Ttc3
|
UTSW |
16 |
94,236,389 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9129:Ttc3
|
UTSW |
16 |
94,185,208 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9189:Ttc3
|
UTSW |
16 |
94,268,831 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9217:Ttc3
|
UTSW |
16 |
94,230,467 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9490:Ttc3
|
UTSW |
16 |
94,245,360 (GRCm39) |
missense |
probably benign |
|
|
R9564:Ttc3
|
UTSW |
16 |
94,248,918 (GRCm39) |
missense |
probably benign |
0.07 |
|
X0022:Ttc3
|
UTSW |
16 |
94,243,384 (GRCm39) |
missense |
probably benign |
0.00 |
|
Y5378:Ttc3
|
UTSW |
16 |
94,212,988 (GRCm39) |
splice site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTCGTGAGGCTCAGAGGAAAC -3'
(R):5'- TCACTGGACAAAGGGAACAC -3'
Sequencing Primer
(F):5'- ACTCAGTCCAATGCGCAGG -3'
(R):5'- CCACAAGGGCAAGGGCG -3'
|
| Posted On |
2022-09-12 |
Incidental Mutation