|Institutional Source||Beutler Lab|
|Gene Name||solute carrier family 22 (organic cation transporter), member 13|
|Synonyms||OCTL1, ORCTL3, OCTL3|
|Is this an essential gene?||Probably non essential (E-score: 0.052)|
|Stock #||R0764 (G1)|
|Chromosomal Location||119192974-119209098 bp(-) (GRCm38)|
|Type of Mutation||splice site (3 bp from exon)|
|DNA Base Change (assembly)||T to C at 119208680 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000081855 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000084797] [ENSMUST00000170400]|
|Predicted Effect||probably null
|Predicted Effect||probably benign
|Meta Mutation Damage Score||0.9755|
|Coding Region Coverage||
|Validation Efficiency||98% (48/49)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine. [provided by RefSeq, Sep 2008]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Slc22a13||
(F):5'- CCAGGCCCCTTCTTTAATACACCAG -3'
(R):5'- ACACTTTCAACCTAAGTGCCGCTG -3'
(F):5'- CCTTCTTTAATACACCAGAGGTGG -3'
(R):5'- TAAGTGCCGCTGAGCAG -3'