Incidental Mutation 'R9641:Trip11'
| ID |
726017 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Trip11
|
| Ensembl Gene |
ENSMUSG00000021188 |
| Gene Name |
thyroid hormone receptor interactor 11 |
| Synonyms |
3110031G15Rik, TRIP230, 2610511G22Rik, GMAP-210, 6030460N08Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9641 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
12 |
| Chromosomal Location |
101800304-101879463 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
G to A
at 101859957 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Stop codon
at position 307
(Q307*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000021605
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000021605]
[ENSMUST00000176728]
[ENSMUST00000177183]
[ENSMUST00000177536]
|
| AlphaFold |
E9Q512 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000021605
AA Change: Q307*
|
| SMART Domains |
Protein: ENSMUSP00000021605
Gene: ENSMUSG00000021188
AA Change: Q307*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
54 |
130 |
N/A |
INTRINSIC |
|
coiled coil region
|
167 |
194 |
N/A |
INTRINSIC |
|
coiled coil region
|
218 |
702 |
N/A |
INTRINSIC |
|
coiled coil region
|
754 |
990 |
N/A |
INTRINSIC |
|
coiled coil region
|
1022 |
1051 |
N/A |
INTRINSIC |
|
coiled coil region
|
1196 |
1261 |
N/A |
INTRINSIC |
|
low complexity region
|
1310 |
1322 |
N/A |
INTRINSIC |
|
coiled coil region
|
1336 |
1481 |
N/A |
INTRINSIC |
|
coiled coil region
|
1547 |
1657 |
N/A |
INTRINSIC |
|
coiled coil region
|
1681 |
1771 |
N/A |
INTRINSIC |
|
low complexity region
|
1934 |
1945 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176728
|
| SMART Domains |
Protein: ENSMUSP00000134992
Gene: ENSMUSG00000021188
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
26 |
N/A |
INTRINSIC |
|
Pfam:Orthopox_A5L
|
48 |
282 |
6.5e-9 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000177183
AA Change: Q51*
|
| SMART Domains |
Protein: ENSMUSP00000134976
Gene: ENSMUSG00000021188
AA Change: Q51*
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
33 |
158 |
N/A |
INTRINSIC |
|
coiled coil region
|
179 |
417 |
N/A |
INTRINSIC |
|
coiled coil region
|
469 |
705 |
N/A |
INTRINSIC |
|
coiled coil region
|
737 |
766 |
N/A |
INTRINSIC |
|
coiled coil region
|
911 |
976 |
N/A |
INTRINSIC |
|
low complexity region
|
1025 |
1037 |
N/A |
INTRINSIC |
|
coiled coil region
|
1051 |
1196 |
N/A |
INTRINSIC |
|
coiled coil region
|
1262 |
1372 |
N/A |
INTRINSIC |
|
coiled coil region
|
1396 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1649 |
1660 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000177536
AA Change: Q306*
|
| SMART Domains |
Protein: ENSMUSP00000135669
Gene: ENSMUSG00000021188
AA Change: Q306*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
53 |
129 |
N/A |
INTRINSIC |
|
coiled coil region
|
166 |
193 |
N/A |
INTRINSIC |
|
coiled coil region
|
217 |
517 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene was identified based on the interaction of its protein product with thyroid hormone receptor beta. This protein is associated with the Golgi apparatus. The N-terminal region of the protein binds Golgi membranes and the C-terminal region binds the minus ends of microtubules; thus, the protein is thought to play a role in assembly and maintenance of the Golgi ribbon structure around the centrosome. Mutations in this gene cause achondrogenesis type IA.[provided by RefSeq, Mar 2010]
PHENOTYPE: Mice homozygous for a null allele exhibit neonatal lethality associated with small size, lung hypoplasia, omphalocele, and ventricular septal defects. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(12) : Gene trapped(11) Chemically induced(1)
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700017N19Rik |
T |
C |
10: 100,430,498 (GRCm39) |
F52L |
possibly damaging |
Het |
| Abca16 |
T |
C |
7: 120,126,308 (GRCm39) |
C1156R |
possibly damaging |
Het |
| Abcg3 |
A |
C |
5: 105,084,483 (GRCm39) |
S571A |
probably benign |
Het |
| Abi3 |
C |
A |
11: 95,724,503 (GRCm39) |
L259F |
unknown |
Het |
| Adam19 |
A |
T |
11: 46,027,149 (GRCm39) |
D594V |
probably damaging |
Het |
| Adam34 |
C |
T |
8: 44,104,076 (GRCm39) |
S523N |
probably damaging |
Het |
| Adam6b |
G |
T |
12: 113,454,176 (GRCm39) |
C331F |
probably benign |
Het |
| Adamts14 |
A |
T |
10: 61,106,829 (GRCm39) |
V97E |
probably damaging |
Het |
| Adipor1 |
T |
C |
1: 134,355,878 (GRCm39) |
Y226H |
probably damaging |
Het |
| Alox12e |
T |
C |
11: 70,212,261 (GRCm39) |
Y139C |
probably damaging |
Het |
| Ankrd53 |
A |
G |
6: 83,740,692 (GRCm39) |
D160G |
possibly damaging |
Het |
| Ap1m1 |
A |
T |
8: 73,003,606 (GRCm39) |
Y94F |
probably damaging |
Het |
| Arhgef28 |
A |
C |
13: 98,078,983 (GRCm39) |
D1314E |
probably benign |
Het |
| Bicc1 |
A |
G |
10: 70,863,772 (GRCm39) |
I90T |
probably benign |
Het |
| Celf6 |
A |
G |
9: 59,485,833 (GRCm39) |
D58G |
probably damaging |
Het |
| Cfap74 |
T |
C |
4: 155,549,054 (GRCm39) |
S38P |
unknown |
Het |
| Cps1 |
A |
G |
1: 67,234,342 (GRCm39) |
I910V |
probably benign |
Het |
| Cracdl |
C |
T |
1: 37,663,592 (GRCm39) |
A769T |
possibly damaging |
Het |
| Crybg2 |
C |
T |
4: 133,816,620 (GRCm39) |
Q1353* |
probably null |
Het |
| Cyp4f39 |
T |
C |
17: 32,705,982 (GRCm39) |
Y358H |
probably damaging |
Het |
| Dcp1a |
T |
A |
14: 30,241,132 (GRCm39) |
I314N |
probably damaging |
Het |
| Dgki |
A |
C |
6: 37,126,489 (GRCm39) |
W164G |
probably damaging |
Het |
| Dnah8 |
A |
G |
17: 30,932,029 (GRCm39) |
I1466V |
probably benign |
Het |
| Efcab6 |
T |
A |
15: 83,763,676 (GRCm39) |
R1219W |
probably damaging |
Het |
| Faap24 |
A |
T |
7: 35,094,494 (GRCm39) |
F102Y |
probably damaging |
Het |
| Fam186a |
T |
C |
15: 99,838,244 (GRCm39) |
T2667A |
probably benign |
Het |
| Frem1 |
C |
T |
4: 82,877,653 (GRCm39) |
G1308D |
probably damaging |
Het |
| Hectd1 |
T |
C |
12: 51,816,047 (GRCm39) |
T1347A |
probably benign |
Het |
| Hipk3 |
A |
T |
2: 104,267,376 (GRCm39) |
H620Q |
probably benign |
Het |
| Hpd |
A |
G |
5: 123,310,052 (GRCm39) |
S391P |
probably benign |
Het |
| Ino80 |
A |
G |
2: 119,275,965 (GRCm39) |
V437A |
probably benign |
Het |
| Itgax |
G |
T |
7: 127,741,152 (GRCm39) |
G785C |
probably damaging |
Het |
| Kcnk18 |
C |
T |
19: 59,223,266 (GRCm39) |
T137I |
probably damaging |
Het |
| Kif16b |
A |
G |
2: 142,542,589 (GRCm39) |
F236L |
probably benign |
Het |
| Lamb1 |
T |
C |
12: 31,337,457 (GRCm39) |
M396T |
probably damaging |
Het |
| Lrfn5 |
C |
A |
12: 61,886,540 (GRCm39) |
N109K |
probably damaging |
Het |
| Lrrc15 |
T |
A |
16: 30,093,006 (GRCm39) |
N111I |
probably damaging |
Het |
| Lrrk2 |
A |
T |
15: 91,671,251 (GRCm39) |
I2011F |
possibly damaging |
Het |
| Lsr |
A |
G |
7: 30,658,285 (GRCm39) |
I336T |
probably damaging |
Het |
| Mettl21e |
T |
A |
1: 44,250,351 (GRCm39) |
R18S |
probably benign |
Het |
| Mrpl22 |
T |
C |
11: 58,068,047 (GRCm39) |
L115P |
probably damaging |
Het |
| N4bp2 |
T |
A |
5: 65,948,035 (GRCm39) |
S222T |
probably benign |
Het |
| Nat2 |
A |
G |
8: 67,954,522 (GRCm39) |
T211A |
probably benign |
Het |
| Nbeal1 |
T |
A |
1: 60,350,247 (GRCm39) |
I2432N |
probably damaging |
Het |
| Neb |
A |
G |
2: 52,112,783 (GRCm39) |
I1158T |
|
Het |
| Nrip3 |
C |
T |
7: 109,362,793 (GRCm39) |
E164K |
probably damaging |
Het |
| Obox6 |
G |
A |
7: 15,568,742 (GRCm39) |
Q45* |
probably null |
Het |
| Ola1 |
T |
C |
2: 73,033,784 (GRCm39) |
N44D |
probably benign |
Het |
| Or1x6 |
C |
T |
11: 50,939,207 (GRCm39) |
T91M |
probably benign |
Het |
| Or2y1c |
T |
C |
11: 49,361,509 (GRCm39) |
F177S |
probably damaging |
Het |
| Or5b111 |
A |
T |
19: 13,291,100 (GRCm39) |
M183K |
probably damaging |
Het |
| Or5d39 |
A |
T |
2: 87,980,255 (GRCm39) |
I36N |
possibly damaging |
Het |
| Or5p81 |
A |
T |
7: 108,267,516 (GRCm39) |
N298Y |
probably damaging |
Het |
| Or6ae1 |
A |
G |
7: 139,742,771 (GRCm39) |
F31L |
probably benign |
Het |
| Or8b51 |
T |
A |
9: 38,568,915 (GRCm39) |
M258L |
probably benign |
Het |
| Pde10a |
A |
G |
17: 9,197,816 (GRCm39) |
K753R |
|
Het |
| Phldb1 |
T |
C |
9: 44,627,839 (GRCm39) |
D202G |
probably damaging |
Het |
| Pik3cb |
T |
C |
9: 98,955,789 (GRCm39) |
N376S |
probably benign |
Het |
| Plekhh2 |
A |
G |
17: 84,874,130 (GRCm39) |
N472D |
probably damaging |
Het |
| Ppp4r4 |
T |
A |
12: 103,567,811 (GRCm39) |
F708Y |
probably benign |
Het |
| Rnf157 |
A |
G |
11: 116,303,576 (GRCm39) |
V12A |
probably benign |
Het |
| Saa3 |
T |
C |
7: 46,364,494 (GRCm39) |
I11V |
probably benign |
Het |
| Sall2 |
T |
C |
14: 52,550,882 (GRCm39) |
E771G |
probably damaging |
Het |
| Sar1b |
C |
T |
11: 51,670,573 (GRCm39) |
T39I |
probably damaging |
Het |
| Scn10a |
A |
T |
9: 119,445,869 (GRCm39) |
L1428Q |
possibly damaging |
Het |
| Sema3f |
A |
G |
9: 107,565,454 (GRCm39) |
I213T |
unknown |
Het |
| Serpina3m |
C |
T |
12: 104,360,085 (GRCm39) |
Q386* |
probably null |
Het |
| Sh3gl3 |
G |
A |
7: 81,909,370 (GRCm39) |
G26R |
probably damaging |
Het |
| Shq1 |
T |
C |
6: 100,550,633 (GRCm39) |
E435G |
probably damaging |
Het |
| Sidt2 |
G |
T |
9: 45,864,495 (GRCm39) |
A78E |
probably benign |
Het |
| Sin3b |
A |
G |
8: 73,477,187 (GRCm39) |
Y818C |
probably damaging |
Het |
| Smarca2 |
C |
T |
19: 26,656,498 (GRCm39) |
L825F |
possibly damaging |
Het |
| Srgn |
T |
A |
10: 62,330,884 (GRCm39) |
M74L |
probably benign |
Het |
| Tbc1d22b |
A |
C |
17: 29,813,747 (GRCm39) |
D360A |
possibly damaging |
Het |
| Tbx4 |
A |
G |
11: 85,803,128 (GRCm39) |
R335G |
probably damaging |
Het |
| Tmem144 |
T |
C |
3: 79,734,200 (GRCm39) |
N168D |
probably benign |
Het |
| Ttyh2 |
T |
C |
11: 114,598,516 (GRCm39) |
Y296H |
probably damaging |
Het |
| Vmn1r236 |
G |
T |
17: 21,507,043 (GRCm39) |
V54F |
probably benign |
Het |
| Xrra1 |
A |
C |
7: 99,561,088 (GRCm39) |
H443P |
probably benign |
Het |
| Zc3h12a |
T |
C |
4: 125,014,852 (GRCm39) |
T211A |
probably damaging |
Het |
| Zfp386 |
T |
G |
12: 116,023,330 (GRCm39) |
D349E |
probably benign |
Het |
| Zkscan16 |
T |
A |
4: 58,956,577 (GRCm39) |
H286Q |
probably benign |
Het |
| Znrf2 |
C |
T |
6: 54,861,788 (GRCm39) |
P233L |
probably damaging |
Het |
|
| Other mutations in Trip11 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00430:Trip11
|
APN |
12 |
101,852,406 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL00484:Trip11
|
APN |
12 |
101,851,570 (GRCm39) |
nonsense |
probably null |
|
|
IGL00972:Trip11
|
APN |
12 |
101,860,596 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL01476:Trip11
|
APN |
12 |
101,865,170 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01591:Trip11
|
APN |
12 |
101,849,604 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01667:Trip11
|
APN |
12 |
101,845,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01764:Trip11
|
APN |
12 |
101,850,890 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01789:Trip11
|
APN |
12 |
101,838,090 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01814:Trip11
|
APN |
12 |
101,850,747 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01898:Trip11
|
APN |
12 |
101,851,935 (GRCm39) |
missense |
probably benign |
|
|
IGL01924:Trip11
|
APN |
12 |
101,853,143 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02020:Trip11
|
APN |
12 |
101,850,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02475:Trip11
|
APN |
12 |
101,861,942 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02544:Trip11
|
APN |
12 |
101,859,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02678:Trip11
|
APN |
12 |
101,849,649 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02714:Trip11
|
APN |
12 |
101,850,260 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02718:Trip11
|
APN |
12 |
101,852,284 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL02904:Trip11
|
APN |
12 |
101,853,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03012:Trip11
|
APN |
12 |
101,850,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03191:Trip11
|
APN |
12 |
101,865,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03327:Trip11
|
APN |
12 |
101,849,677 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL03337:Trip11
|
APN |
12 |
101,851,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
NA:Trip11
|
UTSW |
12 |
101,860,580 (GRCm39) |
splice site |
probably null |
|
|
R0027:Trip11
|
UTSW |
12 |
101,851,428 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0028:Trip11
|
UTSW |
12 |
101,851,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0238:Trip11
|
UTSW |
12 |
101,850,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0238:Trip11
|
UTSW |
12 |
101,850,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0239:Trip11
|
UTSW |
12 |
101,850,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0239:Trip11
|
UTSW |
12 |
101,850,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0505:Trip11
|
UTSW |
12 |
101,851,931 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0556:Trip11
|
UTSW |
12 |
101,850,777 (GRCm39) |
nonsense |
probably null |
|
|
R0573:Trip11
|
UTSW |
12 |
101,853,119 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0626:Trip11
|
UTSW |
12 |
101,852,235 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R1519:Trip11
|
UTSW |
12 |
101,852,419 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1530:Trip11
|
UTSW |
12 |
101,879,026 (GRCm39) |
missense |
unknown |
|
|
R1647:Trip11
|
UTSW |
12 |
101,850,651 (GRCm39) |
nonsense |
probably null |
|
|
R1648:Trip11
|
UTSW |
12 |
101,850,651 (GRCm39) |
nonsense |
probably null |
|
|
R1856:Trip11
|
UTSW |
12 |
101,849,592 (GRCm39) |
nonsense |
probably null |
|
|
R2013:Trip11
|
UTSW |
12 |
101,803,981 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2017:Trip11
|
UTSW |
12 |
101,851,619 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2206:Trip11
|
UTSW |
12 |
101,839,701 (GRCm39) |
missense |
probably benign |
0.25 |
|
R2207:Trip11
|
UTSW |
12 |
101,839,701 (GRCm39) |
missense |
probably benign |
0.25 |
|
R2304:Trip11
|
UTSW |
12 |
101,865,236 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2328:Trip11
|
UTSW |
12 |
101,845,086 (GRCm39) |
makesense |
probably null |
|
|
R2513:Trip11
|
UTSW |
12 |
101,803,986 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3499:Trip11
|
UTSW |
12 |
101,859,953 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4105:Trip11
|
UTSW |
12 |
101,860,581 (GRCm39) |
nonsense |
probably null |
|
|
R4124:Trip11
|
UTSW |
12 |
101,861,957 (GRCm39) |
nonsense |
probably null |
|
|
R4126:Trip11
|
UTSW |
12 |
101,861,957 (GRCm39) |
nonsense |
probably null |
|
|
R4128:Trip11
|
UTSW |
12 |
101,861,957 (GRCm39) |
nonsense |
probably null |
|
|
R4175:Trip11
|
UTSW |
12 |
101,861,957 (GRCm39) |
nonsense |
probably null |
|
|
R4176:Trip11
|
UTSW |
12 |
101,861,957 (GRCm39) |
nonsense |
probably null |
|
|
R4181:Trip11
|
UTSW |
12 |
101,860,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4296:Trip11
|
UTSW |
12 |
101,852,127 (GRCm39) |
nonsense |
probably null |
|
|
R4302:Trip11
|
UTSW |
12 |
101,860,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4306:Trip11
|
UTSW |
12 |
101,853,198 (GRCm39) |
missense |
probably benign |
|
|
R4342:Trip11
|
UTSW |
12 |
101,850,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4576:Trip11
|
UTSW |
12 |
101,852,499 (GRCm39) |
nonsense |
probably null |
|
|
R4586:Trip11
|
UTSW |
12 |
101,849,600 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R4634:Trip11
|
UTSW |
12 |
101,803,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Trip11
|
UTSW |
12 |
101,851,549 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4792:Trip11
|
UTSW |
12 |
101,851,705 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4903:Trip11
|
UTSW |
12 |
101,853,065 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5001:Trip11
|
UTSW |
12 |
101,851,169 (GRCm39) |
nonsense |
probably null |
|
|
R5017:Trip11
|
UTSW |
12 |
101,812,879 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5227:Trip11
|
UTSW |
12 |
101,851,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5231:Trip11
|
UTSW |
12 |
101,851,860 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5539:Trip11
|
UTSW |
12 |
101,851,386 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5754:Trip11
|
UTSW |
12 |
101,851,924 (GRCm39) |
nonsense |
probably null |
|
|
R5755:Trip11
|
UTSW |
12 |
101,851,924 (GRCm39) |
nonsense |
probably null |
|
|
R5890:Trip11
|
UTSW |
12 |
101,852,231 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5910:Trip11
|
UTSW |
12 |
101,849,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6083:Trip11
|
UTSW |
12 |
101,856,001 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6208:Trip11
|
UTSW |
12 |
101,865,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6216:Trip11
|
UTSW |
12 |
101,856,859 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6315:Trip11
|
UTSW |
12 |
101,851,837 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6413:Trip11
|
UTSW |
12 |
101,851,790 (GRCm39) |
missense |
probably benign |
0.12 |
|
R6590:Trip11
|
UTSW |
12 |
101,851,710 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6690:Trip11
|
UTSW |
12 |
101,851,710 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6914:Trip11
|
UTSW |
12 |
101,812,879 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6938:Trip11
|
UTSW |
12 |
101,803,886 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7015:Trip11
|
UTSW |
12 |
101,859,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7023:Trip11
|
UTSW |
12 |
101,852,126 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7133:Trip11
|
UTSW |
12 |
101,850,329 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7271:Trip11
|
UTSW |
12 |
101,850,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7424:Trip11
|
UTSW |
12 |
101,851,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7431:Trip11
|
UTSW |
12 |
101,850,278 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7472:Trip11
|
UTSW |
12 |
101,851,639 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7491:Trip11
|
UTSW |
12 |
101,851,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7752:Trip11
|
UTSW |
12 |
101,853,233 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7763:Trip11
|
UTSW |
12 |
101,811,114 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7779:Trip11
|
UTSW |
12 |
101,849,796 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7844:Trip11
|
UTSW |
12 |
101,844,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8055:Trip11
|
UTSW |
12 |
101,803,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8076:Trip11
|
UTSW |
12 |
101,849,741 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8288:Trip11
|
UTSW |
12 |
101,860,643 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8294:Trip11
|
UTSW |
12 |
101,811,160 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8318:Trip11
|
UTSW |
12 |
101,879,063 (GRCm39) |
missense |
unknown |
|
|
R8690:Trip11
|
UTSW |
12 |
101,839,656 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R8879:Trip11
|
UTSW |
12 |
101,828,857 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8964:Trip11
|
UTSW |
12 |
101,811,315 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9005:Trip11
|
UTSW |
12 |
101,845,131 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9013:Trip11
|
UTSW |
12 |
101,851,377 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9020:Trip11
|
UTSW |
12 |
101,850,770 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9041:Trip11
|
UTSW |
12 |
101,845,127 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9234:Trip11
|
UTSW |
12 |
101,811,990 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9447:Trip11
|
UTSW |
12 |
101,850,148 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9631:Trip11
|
UTSW |
12 |
101,859,807 (GRCm39) |
missense |
probably benign |
|
|
R9691:Trip11
|
UTSW |
12 |
101,850,123 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9751:Trip11
|
UTSW |
12 |
101,850,765 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
X0020:Trip11
|
UTSW |
12 |
101,852,172 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AATCTCAGGACCTCTGCGAC -3'
(R):5'- GTTGTCCAGGTTCTAAACACTCTTAAG -3'
Sequencing Primer
(F):5'- AGCATCACTCTGCCGCAG -3'
(R):5'- TAGGTGGCTCAGGAGTTA -3'
|
| Posted On |
2022-09-12 |
Incidental Mutation