Incidental Mutation 'R9644:Helz'
| ID |
726163 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Helz
|
| Ensembl Gene |
ENSMUSG00000020721 |
| Gene Name |
helicase with zinc finger domain |
| Synonyms |
3110078M01Rik, 9430093I07Rik, 9630002H22Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9644 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
107438756-107584652 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 107563687 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Aspartic acid
at position 1709
(A1709D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000074533
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000075012]
[ENSMUST00000100305]
[ENSMUST00000106746]
[ENSMUST00000133862]
|
| AlphaFold |
Q6DFV5 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000075012
AA Change: A1709D
|
| SMART Domains |
Protein: ENSMUSP00000074533
Gene: ENSMUSG00000020721
AA Change: A1709D
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:ResIII
|
639 |
807 |
6.7e-8 |
PFAM |
|
Pfam:AAA_11
|
641 |
768 |
2.3e-14 |
PFAM |
|
Pfam:AAA_30
|
641 |
838 |
2.6e-11 |
PFAM |
|
Pfam:AAA_19
|
648 |
729 |
5.5e-11 |
PFAM |
|
Pfam:AAA_11
|
758 |
834 |
3.8e-18 |
PFAM |
|
Pfam:AAA_12
|
841 |
1053 |
7.4e-38 |
PFAM |
|
low complexity region
|
1165 |
1176 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1448 |
N/A |
INTRINSIC |
|
low complexity region
|
1466 |
1487 |
N/A |
INTRINSIC |
|
low complexity region
|
1557 |
1568 |
N/A |
INTRINSIC |
|
low complexity region
|
1631 |
1647 |
N/A |
INTRINSIC |
|
low complexity region
|
1716 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
1926 |
1933 |
N/A |
INTRINSIC |
|
low complexity region
|
1942 |
1957 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100305
|
| SMART Domains |
Protein: ENSMUSP00000097878
Gene: ENSMUSG00000020721
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:AAA_11
|
641 |
833 |
2.7e-31 |
PFAM |
|
Pfam:AAA_30
|
641 |
837 |
1.7e-10 |
PFAM |
|
Pfam:AAA_19
|
648 |
727 |
6.3e-9 |
PFAM |
|
Pfam:AAA_12
|
840 |
1052 |
3.4e-36 |
PFAM |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1447 |
N/A |
INTRINSIC |
|
low complexity region
|
1465 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1556 |
1567 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000106746
AA Change: A1708D
|
| SMART Domains |
Protein: ENSMUSP00000102357
Gene: ENSMUSG00000020721
AA Change: A1708D
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:AAA_11
|
641 |
833 |
1e-31 |
PFAM |
|
Pfam:AAA_30
|
641 |
837 |
8.3e-11 |
PFAM |
|
Pfam:AAA_19
|
648 |
727 |
2.2e-9 |
PFAM |
|
Pfam:AAA_12
|
840 |
1052 |
1.7e-36 |
PFAM |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1447 |
N/A |
INTRINSIC |
|
low complexity region
|
1465 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1556 |
1567 |
N/A |
INTRINSIC |
|
low complexity region
|
1630 |
1646 |
N/A |
INTRINSIC |
|
low complexity region
|
1715 |
1735 |
N/A |
INTRINSIC |
|
low complexity region
|
1925 |
1932 |
N/A |
INTRINSIC |
|
low complexity region
|
1941 |
1956 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000133862
|
| SMART Domains |
Protein: ENSMUSP00000117498
Gene: ENSMUSG00000020721
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AAA_11
|
68 |
152 |
2.1e-19 |
PFAM |
|
Pfam:AAA_12
|
159 |
371 |
1.5e-36 |
PFAM |
|
low complexity region
|
483 |
494 |
N/A |
INTRINSIC |
|
low complexity region
|
678 |
766 |
N/A |
INTRINSIC |
|
low complexity region
|
784 |
805 |
N/A |
INTRINSIC |
|
low complexity region
|
875 |
886 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene-trapped allele are viable, fertile and phenotypically normal with no apparent skeletal defects. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acot7 |
C |
A |
4: 152,270,752 (GRCm39) |
S32* |
probably null |
Het |
| Adam34 |
T |
A |
8: 44,104,766 (GRCm39) |
H293L |
probably damaging |
Het |
| Adgrl3 |
A |
G |
5: 81,872,036 (GRCm39) |
N910S |
probably damaging |
Het |
| Ankrd11 |
C |
T |
8: 123,617,682 (GRCm39) |
A2057T |
probably benign |
Het |
| Ankrd36 |
A |
G |
11: 5,593,835 (GRCm39) |
D480G |
possibly damaging |
Het |
| Aox4 |
T |
A |
1: 58,267,278 (GRCm39) |
D185E |
probably benign |
Het |
| Apol8 |
C |
A |
15: 77,633,695 (GRCm39) |
V294L |
probably damaging |
Het |
| Arsk |
G |
A |
13: 76,220,227 (GRCm39) |
A289V |
probably damaging |
Het |
| Atg101 |
A |
G |
15: 101,188,447 (GRCm39) |
D184G |
probably benign |
Het |
| Atp10b |
C |
T |
11: 43,042,659 (GRCm39) |
T73I |
probably damaging |
Het |
| Ccn4 |
T |
G |
15: 66,784,785 (GRCm39) |
C153G |
|
Het |
| Ccser2 |
A |
T |
14: 36,601,150 (GRCm39) |
N411K |
possibly damaging |
Het |
| Cct5 |
A |
G |
15: 31,601,845 (GRCm39) |
S3P |
probably benign |
Het |
| Chn1 |
A |
T |
2: 73,490,184 (GRCm39) |
I31K |
probably benign |
Het |
| Clec2e |
T |
A |
6: 129,070,443 (GRCm39) |
I193L |
probably benign |
Het |
| Crim1 |
G |
A |
17: 78,587,497 (GRCm39) |
G201R |
probably damaging |
Het |
| Ctrc |
A |
G |
4: 141,572,336 (GRCm39) |
V68A |
probably damaging |
Het |
| Dennd4c |
T |
A |
4: 86,713,363 (GRCm39) |
I438N |
probably damaging |
Het |
| Dnah5 |
T |
A |
15: 28,230,650 (GRCm39) |
W183R |
probably damaging |
Het |
| Dnali1 |
T |
A |
4: 124,950,402 (GRCm39) |
I253F |
probably damaging |
Het |
| Dyrk1b |
T |
C |
7: 27,881,790 (GRCm39) |
L83P |
probably damaging |
Het |
| Emx2 |
T |
C |
19: 59,452,427 (GRCm39) |
I237T |
probably benign |
Het |
| Enpp3 |
C |
T |
10: 24,685,801 (GRCm39) |
R198K |
probably damaging |
Het |
| Epb41l1 |
C |
T |
2: 156,367,165 (GRCm39) |
P678L |
possibly damaging |
Het |
| Epm2aip1 |
C |
T |
9: 111,102,137 (GRCm39) |
T370I |
probably damaging |
Het |
| Fam184a |
T |
G |
10: 53,573,342 (GRCm39) |
Q346P |
probably damaging |
Het |
| Foxi2 |
A |
C |
7: 135,013,727 (GRCm39) |
H319P |
possibly damaging |
Het |
| Gatad1 |
A |
G |
5: 3,691,442 (GRCm39) |
V250A |
possibly damaging |
Het |
| Gmeb1 |
T |
C |
4: 131,959,440 (GRCm39) |
I205V |
probably benign |
Het |
| Gucy2g |
C |
G |
19: 55,219,537 (GRCm39) |
V362L |
probably benign |
Het |
| Hace1 |
T |
C |
10: 45,526,001 (GRCm39) |
S281P |
probably benign |
Het |
| Igf2bp2 |
T |
A |
16: 21,902,735 (GRCm39) |
N115Y |
probably damaging |
Het |
| Igkv4-86 |
C |
T |
6: 68,887,593 (GRCm39) |
V49I |
probably benign |
Het |
| Kdm2b |
A |
T |
5: 123,120,842 (GRCm39) |
V101E |
probably damaging |
Het |
| Kidins220 |
A |
G |
12: 25,061,018 (GRCm39) |
D790G |
probably damaging |
Het |
| Kif18a |
A |
G |
2: 109,171,517 (GRCm39) |
T865A |
probably benign |
Het |
| Kif1b |
A |
G |
4: 149,375,836 (GRCm39) |
V10A |
probably damaging |
Het |
| Kmt2d |
A |
T |
15: 98,743,385 (GRCm39) |
M3925K |
unknown |
Het |
| Mcee |
G |
T |
7: 64,061,730 (GRCm39) |
A178S |
possibly damaging |
Het |
| Megf10 |
A |
T |
18: 57,375,773 (GRCm39) |
H233L |
probably benign |
Het |
| Meox1 |
T |
A |
11: 101,769,482 (GRCm39) |
E238V |
probably benign |
Het |
| Myo5a |
G |
A |
9: 75,043,631 (GRCm39) |
G207R |
probably damaging |
Het |
| Nemf |
T |
A |
12: 69,359,436 (GRCm39) |
N966I |
possibly damaging |
Het |
| Or10q3 |
T |
C |
19: 11,848,574 (GRCm39) |
E2G |
probably benign |
Het |
| Or1j14 |
A |
T |
2: 36,417,777 (GRCm39) |
M118L |
probably damaging |
Het |
| Or5b123 |
G |
T |
19: 13,597,344 (GRCm39) |
A230S |
probably benign |
Het |
| Or6c204 |
A |
G |
10: 129,022,738 (GRCm39) |
I184T |
possibly damaging |
Het |
| Pfas |
T |
C |
11: 68,883,542 (GRCm39) |
Q662R |
probably benign |
Het |
| Phf2 |
G |
T |
13: 49,024,218 (GRCm39) |
C8* |
probably null |
Het |
| Pkhd1 |
T |
A |
1: 20,617,690 (GRCm39) |
N965I |
probably benign |
Het |
| Plxnd1 |
C |
T |
6: 115,940,274 (GRCm39) |
R1370Q |
possibly damaging |
Het |
| Prb1b |
T |
A |
6: 132,289,218 (GRCm39) |
Q202L |
unknown |
Het |
| Prdm8 |
A |
T |
5: 98,333,638 (GRCm39) |
T402S |
probably benign |
Het |
| Proz |
T |
A |
8: 13,116,854 (GRCm39) |
D135E |
probably benign |
Het |
| Prtg |
T |
A |
9: 72,813,493 (GRCm39) |
I951K |
probably damaging |
Het |
| Rasgef1b |
A |
T |
5: 99,380,014 (GRCm39) |
Y288* |
probably null |
Het |
| Sacs |
T |
A |
14: 61,443,428 (GRCm39) |
C1825S |
probably benign |
Het |
| Slc22a12 |
G |
C |
19: 6,587,673 (GRCm39) |
P427R |
probably damaging |
Het |
| Slfn3 |
A |
G |
11: 83,105,728 (GRCm39) |
Y575C |
probably damaging |
Het |
| St18 |
C |
T |
1: 6,929,276 (GRCm39) |
T56I |
|
Het |
| Synrg |
T |
C |
11: 83,910,696 (GRCm39) |
L876S |
probably damaging |
Het |
| Tchh |
T |
C |
3: 93,354,666 (GRCm39) |
C1369R |
unknown |
Het |
| Tet2 |
G |
A |
3: 133,193,064 (GRCm39) |
Q457* |
probably null |
Het |
| Thap12 |
T |
C |
7: 98,364,495 (GRCm39) |
V221A |
probably damaging |
Het |
| Tor3a |
T |
A |
1: 156,501,126 (GRCm39) |
D104V |
probably damaging |
Het |
| Trpc2 |
T |
C |
7: 101,744,439 (GRCm39) |
V737A |
possibly damaging |
Het |
| Trpc4 |
A |
G |
3: 54,129,699 (GRCm39) |
Y155C |
probably damaging |
Het |
| Tspyl1 |
T |
C |
10: 34,159,135 (GRCm39) |
S287P |
possibly damaging |
Het |
| Ube2u |
TAGAAGAAGAAGAAGAAGAAGAAGAAGA |
TAGAAGAAGAAGAAGAAGAAGAAGA |
4: 100,406,943 (GRCm39) |
|
probably benign |
Het |
| Ubr2 |
A |
G |
17: 47,266,706 (GRCm39) |
|
probably null |
Het |
| Vmn1r238 |
T |
A |
18: 3,122,635 (GRCm39) |
T260S |
probably benign |
Het |
|
| Other mutations in Helz |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00971:Helz
|
APN |
11 |
107,554,479 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01419:Helz
|
APN |
11 |
107,577,340 (GRCm39) |
missense |
unknown |
|
|
IGL01864:Helz
|
APN |
11 |
107,493,180 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01999:Helz
|
APN |
11 |
107,493,754 (GRCm39) |
splice site |
probably benign |
|
|
IGL02938:Helz
|
APN |
11 |
107,577,264 (GRCm39) |
missense |
unknown |
|
|
IGL03157:Helz
|
APN |
11 |
107,468,714 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03374:Helz
|
APN |
11 |
107,510,973 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0058:Helz
|
UTSW |
11 |
107,563,384 (GRCm39) |
unclassified |
probably benign |
|
|
R0058:Helz
|
UTSW |
11 |
107,563,384 (GRCm39) |
unclassified |
probably benign |
|
|
R0112:Helz
|
UTSW |
11 |
107,563,774 (GRCm39) |
unclassified |
probably benign |
|
|
R0243:Helz
|
UTSW |
11 |
107,528,740 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0328:Helz
|
UTSW |
11 |
107,495,174 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0578:Helz
|
UTSW |
11 |
107,577,226 (GRCm39) |
missense |
unknown |
|
|
R0928:Helz
|
UTSW |
11 |
107,517,519 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1428:Helz
|
UTSW |
11 |
107,483,666 (GRCm39) |
splice site |
probably benign |
|
|
R1493:Helz
|
UTSW |
11 |
107,504,751 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1494:Helz
|
UTSW |
11 |
107,494,889 (GRCm39) |
splice site |
probably benign |
|
|
R1541:Helz
|
UTSW |
11 |
107,560,874 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1619:Helz
|
UTSW |
11 |
107,527,105 (GRCm39) |
nonsense |
probably null |
|
|
R1809:Helz
|
UTSW |
11 |
107,489,997 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1942:Helz
|
UTSW |
11 |
107,493,318 (GRCm39) |
missense |
probably benign |
0.20 |
|
R2095:Helz
|
UTSW |
11 |
107,536,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2133:Helz
|
UTSW |
11 |
107,561,310 (GRCm39) |
missense |
unknown |
|
|
R2167:Helz
|
UTSW |
11 |
107,563,790 (GRCm39) |
unclassified |
probably benign |
|
|
R2406:Helz
|
UTSW |
11 |
107,577,378 (GRCm39) |
missense |
unknown |
|
|
R2571:Helz
|
UTSW |
11 |
107,504,778 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2858:Helz
|
UTSW |
11 |
107,563,753 (GRCm39) |
unclassified |
probably benign |
|
|
R3927:Helz
|
UTSW |
11 |
107,576,118 (GRCm39) |
missense |
unknown |
|
|
R4449:Helz
|
UTSW |
11 |
107,494,989 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4453:Helz
|
UTSW |
11 |
107,563,455 (GRCm39) |
nonsense |
probably null |
|
|
R4583:Helz
|
UTSW |
11 |
107,536,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4684:Helz
|
UTSW |
11 |
107,539,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4714:Helz
|
UTSW |
11 |
107,517,542 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4875:Helz
|
UTSW |
11 |
107,528,560 (GRCm39) |
intron |
probably benign |
|
|
R4924:Helz
|
UTSW |
11 |
107,493,165 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4930:Helz
|
UTSW |
11 |
107,510,994 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5078:Helz
|
UTSW |
11 |
107,546,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5446:Helz
|
UTSW |
11 |
107,523,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5535:Helz
|
UTSW |
11 |
107,536,946 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5650:Helz
|
UTSW |
11 |
107,485,972 (GRCm39) |
missense |
probably null |
0.96 |
|
R5714:Helz
|
UTSW |
11 |
107,517,347 (GRCm39) |
splice site |
probably null |
|
|
R5784:Helz
|
UTSW |
11 |
107,561,307 (GRCm39) |
missense |
unknown |
|
|
R5998:Helz
|
UTSW |
11 |
107,576,360 (GRCm39) |
nonsense |
probably null |
|
|
R6042:Helz
|
UTSW |
11 |
107,504,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6089:Helz
|
UTSW |
11 |
107,485,963 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6137:Helz
|
UTSW |
11 |
107,509,886 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6373:Helz
|
UTSW |
11 |
107,486,010 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6392:Helz
|
UTSW |
11 |
107,493,167 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6618:Helz
|
UTSW |
11 |
107,489,976 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6644:Helz
|
UTSW |
11 |
107,523,087 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6811:Helz
|
UTSW |
11 |
107,510,144 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6874:Helz
|
UTSW |
11 |
107,554,460 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6911:Helz
|
UTSW |
11 |
107,510,051 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7039:Helz
|
UTSW |
11 |
107,510,144 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7061:Helz
|
UTSW |
11 |
107,540,003 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7438:Helz
|
UTSW |
11 |
107,552,856 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7464:Helz
|
UTSW |
11 |
107,527,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7513:Helz
|
UTSW |
11 |
107,546,941 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7559:Helz
|
UTSW |
11 |
107,491,104 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7734:Helz
|
UTSW |
11 |
107,576,248 (GRCm39) |
missense |
unknown |
|
|
R7780:Helz
|
UTSW |
11 |
107,528,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7982:Helz
|
UTSW |
11 |
107,517,456 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8024:Helz
|
UTSW |
11 |
107,577,247 (GRCm39) |
missense |
unknown |
|
|
R8181:Helz
|
UTSW |
11 |
107,563,399 (GRCm39) |
missense |
unknown |
|
|
R8346:Helz
|
UTSW |
11 |
107,563,399 (GRCm39) |
missense |
unknown |
|
|
R8729:Helz
|
UTSW |
11 |
107,528,754 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8807:Helz
|
UTSW |
11 |
107,493,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8821:Helz
|
UTSW |
11 |
107,525,919 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8891:Helz
|
UTSW |
11 |
107,552,842 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8909:Helz
|
UTSW |
11 |
107,556,834 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8922:Helz
|
UTSW |
11 |
107,539,985 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8926:Helz
|
UTSW |
11 |
107,563,509 (GRCm39) |
missense |
unknown |
|
|
R8988:Helz
|
UTSW |
11 |
107,495,079 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9053:Helz
|
UTSW |
11 |
107,563,761 (GRCm39) |
missense |
unknown |
|
|
R9056:Helz
|
UTSW |
11 |
107,547,019 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9099:Helz
|
UTSW |
11 |
107,523,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9122:Helz
|
UTSW |
11 |
107,556,830 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9194:Helz
|
UTSW |
11 |
107,561,113 (GRCm39) |
nonsense |
probably null |
|
|
R9220:Helz
|
UTSW |
11 |
107,560,873 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9223:Helz
|
UTSW |
11 |
107,509,918 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9242:Helz
|
UTSW |
11 |
107,523,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9761:Helz
|
UTSW |
11 |
107,560,874 (GRCm39) |
nonsense |
probably null |
|
|
X0065:Helz
|
UTSW |
11 |
107,561,273 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CAAGTTCAGCCTAGAAGTCCG -3'
(R):5'- AGCGAAGAAGCAGACACTGTTC -3'
Sequencing Primer
(F):5'- GACCACAGTAGCCAGTTTGC -3'
(R):5'- GCAGACACTGTTCGAGATGAC -3'
|
| Posted On |
2022-09-12 |
Incidental Mutation