Incidental Mutation 'R9649:Hfm1'
| ID |
726940 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Hfm1
|
| Ensembl Gene |
ENSMUSG00000043410 |
| Gene Name |
HFM1, ATP-dependent DNA helicase homolog |
| Synonyms |
LOC381663, A330009G12Rik, Mer3, Sec63d1 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.086)
|
| Stock # |
R9649 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
106840192-106926321 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 106918463 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 33
(D33V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142727
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000112690]
[ENSMUST00000117588]
[ENSMUST00000148686]
[ENSMUST00000200249]
|
| AlphaFold |
D3Z4R1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000112690
AA Change: D33V
PolyPhen 2
Score 0.819 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000108310
Gene: ENSMUSG00000043410
AA Change: D33V
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000117588
AA Change: D33V
PolyPhen 2
Score 0.819 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000112590
Gene: ENSMUSG00000043410
AA Change: D33V
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000148686
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000200249
AA Change: D33V
PolyPhen 2
Score 0.819 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000142727
Gene: ENSMUSG00000043410
AA Change: D33V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ResIII
|
260 |
410 |
9.9e-7 |
PFAM |
|
Pfam:DEAD
|
281 |
410 |
1.5e-19 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is thought to be an ATP-dependent DNA helicase and is expressed mainly in germ-line cells. Defects in this gene are a cause of premature ovarian failure 9 (POF9). [provided by RefSeq, Apr 2014]
PHENOTYPE: Meiosis ais disrupted in homozygotes and bothe sexes are sterile [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010B08Rik |
A |
T |
2: 173,719,913 (GRCm38) |
H5L |
unknown |
Het |
| Aatk |
A |
G |
11: 120,010,907 (GRCm38) |
S888P |
probably damaging |
Het |
| Ahnak |
A |
T |
19: 9,008,422 (GRCm38) |
K2357* |
probably null |
Het |
| Arl9 |
T |
A |
5: 77,007,292 (GRCm38) |
L90Q |
probably damaging |
Het |
| Atxn2 |
T |
C |
5: 121,810,992 (GRCm38) |
V1144A |
probably damaging |
Het |
| Batf3 |
C |
T |
1: 191,098,426 (GRCm38) |
|
probably benign |
Het |
| Brpf3 |
G |
A |
17: 28,818,623 (GRCm38) |
E822K |
probably benign |
Het |
| Cabin1 |
T |
A |
10: 75,739,405 (GRCm38) |
Q602L |
probably damaging |
Het |
| Cadps |
T |
C |
14: 12,597,418 (GRCm38) |
E424G |
probably damaging |
Het |
| Camta1 |
A |
G |
4: 151,131,547 (GRCm38) |
L972P |
possibly damaging |
Het |
| Ccdc159 |
A |
G |
9: 21,929,376 (GRCm38) |
N80D |
possibly damaging |
Het |
| Cdh1 |
A |
C |
8: 106,661,972 (GRCm38) |
E553D |
possibly damaging |
Het |
| Cdk14 |
T |
A |
5: 5,373,477 (GRCm38) |
E35V |
probably benign |
Het |
| Cfap70 |
A |
G |
14: 20,400,478 (GRCm38) |
L995P |
probably damaging |
Het |
| Col18a1 |
T |
A |
10: 77,080,839 (GRCm38) |
E334V |
unknown |
Het |
| Colec12 |
T |
A |
18: 9,877,000 (GRCm38) |
I741K |
unknown |
Het |
| Crot |
A |
G |
5: 8,974,170 (GRCm38) |
V342A |
probably benign |
Het |
| Ctnnal1 |
A |
G |
4: 56,865,036 (GRCm38) |
S27P |
possibly damaging |
Het |
| Cyp2j9 |
A |
G |
4: 96,571,956 (GRCm38) |
S437P |
probably damaging |
Het |
| Dennd4c |
A |
T |
4: 86,824,923 (GRCm38) |
T1001S |
probably benign |
Het |
| Dffa |
G |
A |
4: 149,117,819 (GRCm38) |
V227I |
probably benign |
Het |
| Dnaaf5 |
T |
A |
5: 139,174,154 (GRCm38) |
H602Q |
probably benign |
Het |
| Efcab7 |
G |
T |
4: 99,904,705 (GRCm38) |
K397N |
probably damaging |
Het |
| Egfl6 |
C |
T |
X: 166,536,239 (GRCm38) |
V379I |
probably benign |
Het |
| Fadd |
G |
A |
7: 144,580,647 (GRCm38) |
T167I |
probably benign |
Het |
| Fam184b |
T |
C |
5: 45,639,142 (GRCm38) |
D33G |
probably damaging |
Het |
| Fam214a |
A |
G |
9: 75,017,067 (GRCm38) |
D864G |
possibly damaging |
Het |
| Fam83h |
G |
A |
15: 76,006,127 (GRCm38) |
R141W |
probably damaging |
Het |
| Fam84a |
T |
C |
12: 14,150,189 (GRCm38) |
N179S |
probably benign |
Het |
| Fanci |
G |
A |
7: 79,427,206 (GRCm38) |
R564Q |
probably damaging |
Het |
| Fat3 |
A |
T |
9: 15,996,758 (GRCm38) |
D2649E |
possibly damaging |
Het |
| Fcrl1 |
A |
G |
3: 87,384,611 (GRCm38) |
T46A |
possibly damaging |
Het |
| Fig4 |
C |
T |
10: 41,267,767 (GRCm38) |
G232D |
probably benign |
Het |
| Frem3 |
A |
T |
8: 80,614,516 (GRCm38) |
H1146L |
probably damaging |
Het |
| Fyttd1 |
T |
A |
16: 32,895,102 (GRCm38) |
F133L |
probably benign |
Het |
| Gata2 |
A |
G |
6: 88,202,523 (GRCm38) |
N326D |
probably damaging |
Het |
| Gm10093 |
A |
T |
17: 78,491,646 (GRCm38) |
Y22F |
probably benign |
Het |
| Gm13084 |
A |
G |
4: 143,816,039 (GRCm38) |
C4R |
probably damaging |
Het |
| Gm21964 |
T |
C |
8: 110,110,948 (GRCm38) |
F375L |
probably damaging |
Het |
| Gm7298 |
A |
T |
6: 121,787,532 (GRCm38) |
T1457S |
probably damaging |
Het |
| Gm8773 |
C |
T |
5: 5,575,549 (GRCm38) |
Q82* |
probably null |
Het |
| Heatr5b |
C |
T |
17: 78,834,095 (GRCm38) |
|
probably null |
Het |
| Hmcn2 |
G |
A |
2: 31,402,438 (GRCm38) |
A2447T |
possibly damaging |
Het |
| Hs3st3b1 |
A |
G |
11: 63,921,505 (GRCm38) |
F128S |
probably benign |
Het |
| Hs3st6 |
G |
T |
17: 24,753,252 (GRCm38) |
R56L |
possibly damaging |
Het |
| Hsd17b3 |
C |
T |
13: 64,064,357 (GRCm38) |
M168I |
probably damaging |
Het |
| Ighv1-34 |
G |
T |
12: 114,851,265 (GRCm38) |
D92E |
possibly damaging |
Het |
| Itgb4 |
A |
T |
11: 115,994,345 (GRCm38) |
I1018F |
possibly damaging |
Het |
| Itih3 |
T |
C |
14: 30,915,648 (GRCm38) |
D518G |
possibly damaging |
Het |
| Kcnma1 |
C |
T |
14: 23,451,598 (GRCm38) |
|
probably null |
Het |
| Klhl11 |
A |
T |
11: 100,472,680 (GRCm38) |
S17T |
probably benign |
Het |
| Lilra6 |
T |
C |
7: 3,914,522 (GRCm38) |
E158G |
possibly damaging |
Het |
| Loxl1 |
A |
G |
9: 58,312,754 (GRCm38) |
W45R |
probably damaging |
Het |
| Lrfn1 |
G |
T |
7: 28,466,830 (GRCm38) |
V550F |
probably damaging |
Het |
| Lrp1 |
T |
C |
10: 127,573,499 (GRCm38) |
K1584E |
probably benign |
Het |
| Lrp4 |
C |
G |
2: 91,508,569 (GRCm38) |
P1782A |
possibly damaging |
Het |
| Map3k1 |
A |
G |
13: 111,748,944 (GRCm38) |
S1480P |
probably damaging |
Het |
| Mark4 |
G |
T |
7: 19,426,090 (GRCm38) |
N748K |
probably benign |
Het |
| Mrpl38 |
G |
A |
11: 116,135,074 (GRCm38) |
T142M |
probably damaging |
Het |
| Mrpl41 |
T |
C |
2: 24,974,469 (GRCm38) |
T64A |
probably benign |
Het |
| Mrps2 |
G |
A |
2: 28,469,752 (GRCm38) |
R207K |
possibly damaging |
Het |
| Myo5a |
A |
T |
9: 75,192,444 (GRCm38) |
E96D |
|
Het |
| Nbas |
A |
T |
12: 13,583,416 (GRCm38) |
E2274V |
probably damaging |
Het |
| Olfr1022 |
T |
C |
2: 85,868,934 (GRCm38) |
L114P |
possibly damaging |
Het |
| Olfr1022 |
T |
A |
2: 85,869,475 (GRCm38) |
N294K |
probably damaging |
Het |
| Olfr1274-ps |
T |
C |
2: 90,400,994 (GRCm38) |
F111S |
probably damaging |
Het |
| Olfr570 |
T |
C |
7: 102,900,445 (GRCm38) |
I26T |
probably benign |
Het |
| Olfr616 |
T |
C |
7: 103,564,643 (GRCm38) |
D212G |
probably damaging |
Het |
| Olfr781 |
T |
A |
10: 129,333,499 (GRCm38) |
I206N |
possibly damaging |
Het |
| Pcdhga12 |
T |
A |
18: 37,767,235 (GRCm38) |
D373E |
probably damaging |
Het |
| Pgd |
A |
C |
4: 149,151,139 (GRCm38) |
F395V |
probably damaging |
Het |
| Pi16 |
A |
G |
17: 29,319,389 (GRCm38) |
M59V |
possibly damaging |
Het |
| Pik3r5 |
A |
T |
11: 68,490,894 (GRCm38) |
T255S |
probably benign |
Het |
| Plch2 |
A |
T |
4: 154,984,059 (GRCm38) |
V1370E |
probably benign |
Het |
| Plec |
A |
G |
15: 76,182,953 (GRCm38) |
I1309T |
unknown |
Het |
| Ppp2r3d |
A |
T |
9: 124,440,831 (GRCm38) |
S22R |
|
Het |
| Ptk2b |
C |
A |
14: 66,175,705 (GRCm38) |
E342* |
probably null |
Het |
| Ptpn23 |
T |
C |
9: 110,386,158 (GRCm38) |
|
probably null |
Het |
| Rfx8 |
A |
C |
1: 39,683,690 (GRCm38) |
S256A |
probably damaging |
Het |
| Rnf115 |
C |
T |
3: 96,758,021 (GRCm38) |
T69I |
probably damaging |
Het |
| Rnf213 |
A |
G |
11: 119,479,631 (GRCm38) |
Y4753C |
|
Het |
| S100a10 |
A |
C |
3: 93,564,283 (GRCm38) |
D58A |
possibly damaging |
Het |
| Serpina12 |
T |
C |
12: 104,038,058 (GRCm38) |
K105R |
probably benign |
Het |
| Slc20a2 |
G |
A |
8: 22,538,884 (GRCm38) |
G124S |
probably damaging |
Het |
| Stab2 |
ACC |
AC |
10: 86,856,697 (GRCm38) |
|
probably null |
Het |
| Stard9 |
C |
A |
2: 120,696,154 (GRCm38) |
T964N |
probably benign |
Het |
| Stxbp5 |
T |
A |
10: 9,899,194 (GRCm38) |
I72F |
probably damaging |
Het |
| Sumf2 |
T |
A |
5: 129,862,641 (GRCm38) |
M282K |
possibly damaging |
Het |
| Tmem135 |
G |
C |
7: 89,147,978 (GRCm38) |
L357V |
probably benign |
Het |
| Tmem185b |
G |
T |
1: 119,526,883 (GRCm38) |
V125L |
probably benign |
Het |
| Tmtc1 |
A |
G |
6: 148,243,216 (GRCm38) |
M887T |
probably damaging |
Het |
| Tnfaip8 |
C |
T |
18: 50,090,445 (GRCm38) |
Q83* |
probably null |
Het |
| Tnks |
A |
G |
8: 34,838,935 (GRCm38) |
V1162A |
probably damaging |
Het |
| Tomm70a |
T |
A |
16: 57,140,709 (GRCm38) |
Y342N |
possibly damaging |
Het |
| Tpo |
T |
A |
12: 30,075,876 (GRCm38) |
D828V |
probably damaging |
Het |
| Ugt8a |
A |
T |
3: 125,914,689 (GRCm38) |
N257K |
probably damaging |
Het |
| Uhrf1bp1l |
C |
A |
10: 89,790,731 (GRCm38) |
T429K |
probably benign |
Het |
| Unc13d |
AATGCCTCCCATGCC |
AATGCCTCCCATGCCTCCCATGCC |
11: 116,068,172 (GRCm38) |
|
probably benign |
Het |
| Vim |
T |
A |
2: 13,574,892 (GRCm38) |
M154K |
probably damaging |
Het |
| Virma |
G |
T |
4: 11,486,045 (GRCm38) |
M1I |
probably null |
Het |
| Zfp715 |
A |
T |
7: 43,301,229 (GRCm38) |
M100K |
probably benign |
Het |
| Zfp748 |
A |
T |
13: 67,542,528 (GRCm38) |
C204* |
probably null |
Het |
| Zmynd8 |
A |
T |
2: 165,838,852 (GRCm38) |
D236E |
probably damaging |
Het |
|
| Other mutations in Hfm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00944:Hfm1
|
APN |
5 |
106,902,130 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
IGL01295:Hfm1
|
APN |
5 |
106,917,606 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
IGL01725:Hfm1
|
APN |
5 |
106,917,379 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01758:Hfm1
|
APN |
5 |
106,904,793 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01911:Hfm1
|
APN |
5 |
106,911,544 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL02337:Hfm1
|
APN |
5 |
106,904,267 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
IGL02472:Hfm1
|
APN |
5 |
106,873,928 (GRCm38) |
splice site |
probably benign |
|
|
IGL02496:Hfm1
|
APN |
5 |
106,901,761 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02545:Hfm1
|
APN |
5 |
106,895,287 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02584:Hfm1
|
APN |
5 |
106,878,662 (GRCm38) |
splice site |
probably null |
|
|
IGL02728:Hfm1
|
APN |
5 |
106,878,823 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL02881:Hfm1
|
APN |
5 |
106,874,252 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03108:Hfm1
|
APN |
5 |
106,895,934 (GRCm38) |
unclassified |
probably benign |
|
|
IGL03351:Hfm1
|
APN |
5 |
106,911,575 (GRCm38) |
nonsense |
probably null |
|
|
IGL03353:Hfm1
|
APN |
5 |
106,856,929 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0024:Hfm1
|
UTSW |
5 |
106,856,924 (GRCm38) |
missense |
probably benign |
0.41 |
|
R0024:Hfm1
|
UTSW |
5 |
106,856,924 (GRCm38) |
missense |
probably benign |
0.41 |
|
R0094:Hfm1
|
UTSW |
5 |
106,917,478 (GRCm38) |
missense |
probably benign |
|
|
R0633:Hfm1
|
UTSW |
5 |
106,917,601 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R0644:Hfm1
|
UTSW |
5 |
106,898,256 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1078:Hfm1
|
UTSW |
5 |
106,878,830 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1120:Hfm1
|
UTSW |
5 |
106,904,218 (GRCm38) |
splice site |
probably benign |
|
|
R1166:Hfm1
|
UTSW |
5 |
106,911,411 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1242:Hfm1
|
UTSW |
5 |
106,874,901 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1414:Hfm1
|
UTSW |
5 |
106,872,353 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1450:Hfm1
|
UTSW |
5 |
106,918,458 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1529:Hfm1
|
UTSW |
5 |
106,853,123 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1622:Hfm1
|
UTSW |
5 |
106,893,523 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R1710:Hfm1
|
UTSW |
5 |
106,896,003 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1710:Hfm1
|
UTSW |
5 |
106,880,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1757:Hfm1
|
UTSW |
5 |
106,880,360 (GRCm38) |
splice site |
probably null |
|
|
R1856:Hfm1
|
UTSW |
5 |
106,847,676 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1984:Hfm1
|
UTSW |
5 |
106,898,576 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1985:Hfm1
|
UTSW |
5 |
106,898,576 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R2040:Hfm1
|
UTSW |
5 |
106,901,818 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2122:Hfm1
|
UTSW |
5 |
106,896,255 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2426:Hfm1
|
UTSW |
5 |
106,847,653 (GRCm38) |
splice site |
probably null |
|
|
R2474:Hfm1
|
UTSW |
5 |
106,872,416 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R2926:Hfm1
|
UTSW |
5 |
106,874,282 (GRCm38) |
nonsense |
probably null |
|
|
R2944:Hfm1
|
UTSW |
5 |
106,872,330 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3705:Hfm1
|
UTSW |
5 |
106,892,839 (GRCm38) |
unclassified |
probably benign |
|
|
R4256:Hfm1
|
UTSW |
5 |
106,904,797 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R4455:Hfm1
|
UTSW |
5 |
106,886,508 (GRCm38) |
splice site |
probably null |
|
|
R4538:Hfm1
|
UTSW |
5 |
106,874,890 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R4540:Hfm1
|
UTSW |
5 |
106,874,221 (GRCm38) |
nonsense |
probably null |
|
|
R4591:Hfm1
|
UTSW |
5 |
106,847,667 (GRCm38) |
missense |
probably benign |
0.08 |
|
R4745:Hfm1
|
UTSW |
5 |
106,901,843 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R4747:Hfm1
|
UTSW |
5 |
106,917,523 (GRCm38) |
missense |
probably benign |
|
|
R4765:Hfm1
|
UTSW |
5 |
106,842,539 (GRCm38) |
missense |
probably benign |
0.21 |
|
R4821:Hfm1
|
UTSW |
5 |
106,854,740 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4842:Hfm1
|
UTSW |
5 |
106,892,751 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4944:Hfm1
|
UTSW |
5 |
106,874,213 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R5093:Hfm1
|
UTSW |
5 |
106,901,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5399:Hfm1
|
UTSW |
5 |
106,917,562 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R5414:Hfm1
|
UTSW |
5 |
106,902,076 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5436:Hfm1
|
UTSW |
5 |
106,892,772 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R5459:Hfm1
|
UTSW |
5 |
106,904,763 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5485:Hfm1
|
UTSW |
5 |
106,847,662 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5585:Hfm1
|
UTSW |
5 |
106,911,439 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5631:Hfm1
|
UTSW |
5 |
106,904,763 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5705:Hfm1
|
UTSW |
5 |
106,911,453 (GRCm38) |
missense |
probably benign |
0.21 |
|
R5804:Hfm1
|
UTSW |
5 |
106,878,589 (GRCm38) |
splice site |
probably null |
|
|
R5959:Hfm1
|
UTSW |
5 |
106,874,917 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6046:Hfm1
|
UTSW |
5 |
106,898,643 (GRCm38) |
splice site |
probably null |
|
|
R6191:Hfm1
|
UTSW |
5 |
106,886,553 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6345:Hfm1
|
UTSW |
5 |
106,841,638 (GRCm38) |
missense |
probably benign |
|
|
R6580:Hfm1
|
UTSW |
5 |
106,847,709 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6651:Hfm1
|
UTSW |
5 |
106,847,687 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6761:Hfm1
|
UTSW |
5 |
106,895,279 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6835:Hfm1
|
UTSW |
5 |
106,878,815 (GRCm38) |
nonsense |
probably null |
|
|
R6891:Hfm1
|
UTSW |
5 |
106,917,374 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R6924:Hfm1
|
UTSW |
5 |
106,850,410 (GRCm38) |
splice site |
probably null |
|
|
R6980:Hfm1
|
UTSW |
5 |
106,880,477 (GRCm38) |
missense |
probably benign |
0.31 |
|
R7054:Hfm1
|
UTSW |
5 |
106,896,043 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7058:Hfm1
|
UTSW |
5 |
106,911,440 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7189:Hfm1
|
UTSW |
5 |
106,901,703 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7250:Hfm1
|
UTSW |
5 |
106,904,331 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7376:Hfm1
|
UTSW |
5 |
106,895,218 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R7577:Hfm1
|
UTSW |
5 |
106,896,043 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7636:Hfm1
|
UTSW |
5 |
106,917,466 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7639:Hfm1
|
UTSW |
5 |
106,898,475 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7639:Hfm1
|
UTSW |
5 |
106,889,925 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7763:Hfm1
|
UTSW |
5 |
106,881,861 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7828:Hfm1
|
UTSW |
5 |
106,881,791 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7905:Hfm1
|
UTSW |
5 |
106,898,553 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8160:Hfm1
|
UTSW |
5 |
106,896,033 (GRCm38) |
missense |
probably null |
0.00 |
|
R8477:Hfm1
|
UTSW |
5 |
106,881,818 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8739:Hfm1
|
UTSW |
5 |
106,898,505 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8968:Hfm1
|
UTSW |
5 |
106,917,573 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9072:Hfm1
|
UTSW |
5 |
106,898,280 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9073:Hfm1
|
UTSW |
5 |
106,898,280 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9152:Hfm1
|
UTSW |
5 |
106,841,745 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9234:Hfm1
|
UTSW |
5 |
106,893,468 (GRCm38) |
missense |
probably benign |
|
|
R9244:Hfm1
|
UTSW |
5 |
106,874,900 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9576:Hfm1
|
UTSW |
5 |
106,874,072 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9743:Hfm1
|
UTSW |
5 |
106,874,259 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R9782:Hfm1
|
UTSW |
5 |
106,874,030 (GRCm38) |
missense |
probably benign |
0.38 |
|
R9789:Hfm1
|
UTSW |
5 |
106,917,480 (GRCm38) |
missense |
probably benign |
0.00 |
|
Z1177:Hfm1
|
UTSW |
5 |
106,871,820 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CAAGGCACATGTGTGGTAGTG -3'
(R):5'- TGATATTGAGAGCAGTGACACAC -3'
Sequencing Primer
(F):5'- CACATGTGTGGTAGTGATTATGCAC -3'
(R):5'- CAGTGACACACAAGGATAAAGC -3'
|
| Posted On |
2022-10-06 |
Incidental Mutation