Incidental Mutation 'R9649:Nbas'
| ID |
726984 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nbas
|
| Ensembl Gene |
ENSMUSG00000020576 |
| Gene Name |
neuroblastoma amplified sequence |
| Synonyms |
4933425L03Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9649 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
12 |
| Chromosomal Location |
13319134-13633812 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 13633417 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Valine
at position 2274
(E2274V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000036082
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042953]
|
| AlphaFold |
E9Q411 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000042953
AA Change: E2274V
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000036082
Gene: ENSMUSG00000020576
AA Change: E2274V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nbas_N
|
89 |
370 |
4.7e-171 |
PFAM |
|
low complexity region
|
463 |
475 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
667 |
N/A |
INTRINSIC |
|
Pfam:Sec39
|
725 |
1375 |
3.8e-34 |
PFAM |
|
low complexity region
|
1392 |
1404 |
N/A |
INTRINSIC |
|
low complexity region
|
1549 |
1566 |
N/A |
INTRINSIC |
|
low complexity region
|
2226 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2275 |
2285 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. [provided by RefSeq, Oct 2012]
|
| Allele List at MGI |
All alleles(10) : Targeted, other(2) Gene trapped(8)
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010B08Rik |
A |
T |
2: 173,561,706 (GRCm39) |
H5L |
unknown |
Het |
| Aatk |
A |
G |
11: 119,901,733 (GRCm39) |
S888P |
probably damaging |
Het |
| Ahnak |
A |
T |
19: 8,985,786 (GRCm39) |
K2357* |
probably null |
Het |
| Arl9 |
T |
A |
5: 77,155,139 (GRCm39) |
L90Q |
probably damaging |
Het |
| Atosa |
A |
G |
9: 74,924,349 (GRCm39) |
D864G |
possibly damaging |
Het |
| Atxn2 |
T |
C |
5: 121,949,055 (GRCm39) |
V1144A |
probably damaging |
Het |
| Batf3 |
C |
T |
1: 190,830,623 (GRCm39) |
|
probably benign |
Het |
| Bltp3b |
C |
A |
10: 89,626,593 (GRCm39) |
T429K |
probably benign |
Het |
| Brpf3 |
G |
A |
17: 29,037,597 (GRCm39) |
E822K |
probably benign |
Het |
| Cabin1 |
T |
A |
10: 75,575,239 (GRCm39) |
Q602L |
probably damaging |
Het |
| Cadps |
T |
C |
14: 12,597,418 (GRCm38) |
E424G |
probably damaging |
Het |
| Camta1 |
A |
G |
4: 151,216,004 (GRCm39) |
L972P |
possibly damaging |
Het |
| Ccdc159 |
A |
G |
9: 21,840,672 (GRCm39) |
N80D |
possibly damaging |
Het |
| Cdh1 |
A |
C |
8: 107,388,604 (GRCm39) |
E553D |
possibly damaging |
Het |
| Cdk14 |
T |
A |
5: 5,423,477 (GRCm39) |
E35V |
probably benign |
Het |
| Cfap70 |
A |
G |
14: 20,450,546 (GRCm39) |
L995P |
probably damaging |
Het |
| Col18a1 |
T |
A |
10: 76,916,673 (GRCm39) |
E334V |
unknown |
Het |
| Colec12 |
T |
A |
18: 9,877,000 (GRCm39) |
I741K |
unknown |
Het |
| Crot |
A |
G |
5: 9,024,170 (GRCm39) |
V342A |
probably benign |
Het |
| Ctnnal1 |
A |
G |
4: 56,865,036 (GRCm39) |
S27P |
possibly damaging |
Het |
| Cyp2j9 |
A |
G |
4: 96,460,193 (GRCm39) |
S437P |
probably damaging |
Het |
| Dennd4c |
A |
T |
4: 86,743,160 (GRCm39) |
T1001S |
probably benign |
Het |
| Dffa |
G |
A |
4: 149,202,276 (GRCm39) |
V227I |
probably benign |
Het |
| Dnaaf5 |
T |
A |
5: 139,159,909 (GRCm39) |
H602Q |
probably benign |
Het |
| Efcab7 |
G |
T |
4: 99,761,902 (GRCm39) |
K397N |
probably damaging |
Het |
| Egfl6 |
C |
T |
X: 165,319,235 (GRCm39) |
V379I |
probably benign |
Het |
| Fadd |
G |
A |
7: 144,134,384 (GRCm39) |
T167I |
probably benign |
Het |
| Fam184b |
T |
C |
5: 45,796,484 (GRCm39) |
D33G |
probably damaging |
Het |
| Fam237b |
C |
T |
5: 5,625,549 (GRCm39) |
Q82* |
probably null |
Het |
| Fam83h |
G |
A |
15: 75,877,976 (GRCm39) |
R141W |
probably damaging |
Het |
| Fanci |
G |
A |
7: 79,076,954 (GRCm39) |
R564Q |
probably damaging |
Het |
| Fat3 |
A |
T |
9: 15,908,054 (GRCm39) |
D2649E |
possibly damaging |
Het |
| Fcrl1 |
A |
G |
3: 87,291,918 (GRCm39) |
T46A |
possibly damaging |
Het |
| Fig4 |
C |
T |
10: 41,143,763 (GRCm39) |
G232D |
probably benign |
Het |
| Frem3 |
A |
T |
8: 81,341,145 (GRCm39) |
H1146L |
probably damaging |
Het |
| Fyttd1 |
T |
A |
16: 32,715,472 (GRCm39) |
F133L |
probably benign |
Het |
| Gata2 |
A |
G |
6: 88,179,505 (GRCm39) |
N326D |
probably damaging |
Het |
| Gm7298 |
A |
T |
6: 121,764,491 (GRCm39) |
T1457S |
probably damaging |
Het |
| Hdac1-ps |
A |
T |
17: 78,799,075 (GRCm39) |
Y22F |
probably benign |
Het |
| Heatr5b |
C |
T |
17: 79,141,524 (GRCm39) |
|
probably null |
Het |
| Hfm1 |
T |
A |
5: 107,066,329 (GRCm39) |
D33V |
possibly damaging |
Het |
| Hmcn2 |
G |
A |
2: 31,292,450 (GRCm39) |
A2447T |
possibly damaging |
Het |
| Hs3st3b1 |
A |
G |
11: 63,812,331 (GRCm39) |
F128S |
probably benign |
Het |
| Hs3st6 |
G |
T |
17: 24,972,226 (GRCm39) |
R56L |
possibly damaging |
Het |
| Hsd17b3 |
C |
T |
13: 64,212,171 (GRCm39) |
M168I |
probably damaging |
Het |
| Ighv1-34 |
G |
T |
12: 114,814,885 (GRCm39) |
D92E |
possibly damaging |
Het |
| Itgb4 |
A |
T |
11: 115,885,171 (GRCm39) |
I1018F |
possibly damaging |
Het |
| Itih3 |
T |
C |
14: 30,637,605 (GRCm39) |
D518G |
possibly damaging |
Het |
| Kcnma1 |
C |
T |
14: 23,501,666 (GRCm39) |
|
probably null |
Het |
| Klhl11 |
A |
T |
11: 100,363,506 (GRCm39) |
S17T |
probably benign |
Het |
| Lilra6 |
T |
C |
7: 3,917,521 (GRCm39) |
E158G |
possibly damaging |
Het |
| Loxl1 |
A |
G |
9: 58,220,037 (GRCm39) |
W45R |
probably damaging |
Het |
| Lratd1 |
T |
C |
12: 14,200,190 (GRCm39) |
N179S |
probably benign |
Het |
| Lrfn1 |
G |
T |
7: 28,166,255 (GRCm39) |
V550F |
probably damaging |
Het |
| Lrp1 |
T |
C |
10: 127,409,368 (GRCm39) |
K1584E |
probably benign |
Het |
| Lrp4 |
C |
G |
2: 91,338,914 (GRCm39) |
P1782A |
possibly damaging |
Het |
| Map3k1 |
A |
G |
13: 111,885,478 (GRCm39) |
S1480P |
probably damaging |
Het |
| Mark4 |
G |
T |
7: 19,160,015 (GRCm39) |
N748K |
probably benign |
Het |
| Mrpl38 |
G |
A |
11: 116,025,900 (GRCm39) |
T142M |
probably damaging |
Het |
| Mrpl41 |
T |
C |
2: 24,864,481 (GRCm39) |
T64A |
probably benign |
Het |
| Mrps2 |
G |
A |
2: 28,359,764 (GRCm39) |
R207K |
possibly damaging |
Het |
| Myo5a |
A |
T |
9: 75,099,726 (GRCm39) |
E96D |
|
Het |
| Or4x13 |
T |
C |
2: 90,231,338 (GRCm39) |
F111S |
probably damaging |
Het |
| Or51a8 |
T |
C |
7: 102,549,652 (GRCm39) |
I26T |
probably benign |
Het |
| Or51ac3 |
T |
C |
7: 103,213,850 (GRCm39) |
D212G |
probably damaging |
Het |
| Or5m10b |
T |
C |
2: 85,699,278 (GRCm39) |
L114P |
possibly damaging |
Het |
| Or5m10b |
T |
A |
2: 85,699,819 (GRCm39) |
N294K |
probably damaging |
Het |
| Or6c35 |
T |
A |
10: 129,169,368 (GRCm39) |
I206N |
possibly damaging |
Het |
| Pcdhga12 |
T |
A |
18: 37,900,288 (GRCm39) |
D373E |
probably damaging |
Het |
| Pgd |
A |
C |
4: 149,235,596 (GRCm39) |
F395V |
probably damaging |
Het |
| Pi16 |
A |
G |
17: 29,538,363 (GRCm39) |
M59V |
possibly damaging |
Het |
| Pik3r5 |
A |
T |
11: 68,381,720 (GRCm39) |
T255S |
probably benign |
Het |
| Plch2 |
A |
T |
4: 155,068,516 (GRCm39) |
V1370E |
probably benign |
Het |
| Plec |
A |
G |
15: 76,067,153 (GRCm39) |
I1309T |
unknown |
Het |
| Ppp2r3d |
A |
T |
9: 124,440,831 (GRCm38) |
S22R |
|
Het |
| Pramel26 |
A |
G |
4: 143,542,609 (GRCm39) |
C4R |
probably damaging |
Het |
| Ptk2b |
C |
A |
14: 66,413,154 (GRCm39) |
E342* |
probably null |
Het |
| Ptpn23 |
T |
C |
9: 110,215,226 (GRCm39) |
|
probably null |
Het |
| Rfx8 |
A |
C |
1: 39,722,850 (GRCm39) |
S256A |
probably damaging |
Het |
| Rnf115 |
C |
T |
3: 96,665,337 (GRCm39) |
T69I |
probably damaging |
Het |
| Rnf213 |
A |
G |
11: 119,370,457 (GRCm39) |
Y4753C |
|
Het |
| S100a10 |
A |
C |
3: 93,471,590 (GRCm39) |
D58A |
possibly damaging |
Het |
| Serpina12 |
T |
C |
12: 104,004,317 (GRCm39) |
K105R |
probably benign |
Het |
| Slc20a2 |
G |
A |
8: 23,028,900 (GRCm39) |
G124S |
probably damaging |
Het |
| Stab2 |
ACC |
AC |
10: 86,692,561 (GRCm39) |
|
probably null |
Het |
| Stard9 |
C |
A |
2: 120,526,635 (GRCm39) |
T964N |
probably benign |
Het |
| Stxbp5 |
T |
A |
10: 9,774,938 (GRCm39) |
I72F |
probably damaging |
Het |
| Sumf2 |
T |
A |
5: 129,891,482 (GRCm39) |
M282K |
possibly damaging |
Het |
| Tle7 |
T |
C |
8: 110,837,580 (GRCm39) |
F375L |
probably damaging |
Het |
| Tmem135 |
G |
C |
7: 88,797,186 (GRCm39) |
L357V |
probably benign |
Het |
| Tmem185b |
G |
T |
1: 119,454,613 (GRCm39) |
V125L |
probably benign |
Het |
| Tmtc1 |
A |
G |
6: 148,144,714 (GRCm39) |
M887T |
probably damaging |
Het |
| Tnfaip8 |
C |
T |
18: 50,223,512 (GRCm39) |
Q83* |
probably null |
Het |
| Tnks |
A |
G |
8: 35,306,089 (GRCm39) |
V1162A |
probably damaging |
Het |
| Tomm70a |
T |
A |
16: 56,961,072 (GRCm39) |
Y342N |
possibly damaging |
Het |
| Tpo |
T |
A |
12: 30,125,875 (GRCm39) |
D828V |
probably damaging |
Het |
| Ugt8a |
A |
T |
3: 125,708,338 (GRCm39) |
N257K |
probably damaging |
Het |
| Unc13d |
AATGCCTCCCATGCC |
AATGCCTCCCATGCCTCCCATGCC |
11: 115,958,998 (GRCm39) |
|
probably benign |
Het |
| Vim |
T |
A |
2: 13,579,703 (GRCm39) |
M154K |
probably damaging |
Het |
| Virma |
G |
T |
4: 11,486,045 (GRCm39) |
M1I |
probably null |
Het |
| Zfp715 |
A |
T |
7: 42,950,653 (GRCm39) |
M100K |
probably benign |
Het |
| Zfp748 |
A |
T |
13: 67,690,647 (GRCm39) |
C204* |
probably null |
Het |
| Zmynd8 |
A |
T |
2: 165,680,772 (GRCm39) |
D236E |
probably damaging |
Het |
|
| Other mutations in Nbas |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00486:Nbas
|
APN |
12 |
13,503,076 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL00712:Nbas
|
APN |
12 |
13,412,626 (GRCm39) |
splice site |
probably benign |
|
|
IGL00808:Nbas
|
APN |
12 |
13,616,121 (GRCm39) |
splice site |
probably benign |
|
|
IGL00915:Nbas
|
APN |
12 |
13,424,753 (GRCm39) |
nonsense |
probably null |
|
|
IGL00923:Nbas
|
APN |
12 |
13,386,285 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01152:Nbas
|
APN |
12 |
13,410,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01633:Nbas
|
APN |
12 |
13,533,898 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01672:Nbas
|
APN |
12 |
13,429,650 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL01799:Nbas
|
APN |
12 |
13,374,401 (GRCm39) |
splice site |
probably benign |
|
|
IGL01812:Nbas
|
APN |
12 |
13,503,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01934:Nbas
|
APN |
12 |
13,339,880 (GRCm39) |
splice site |
probably benign |
|
|
IGL02093:Nbas
|
APN |
12 |
13,610,963 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02115:Nbas
|
APN |
12 |
13,367,693 (GRCm39) |
splice site |
probably benign |
|
|
IGL02175:Nbas
|
APN |
12 |
13,616,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02268:Nbas
|
APN |
12 |
13,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02483:Nbas
|
APN |
12 |
13,374,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02539:Nbas
|
APN |
12 |
13,322,704 (GRCm39) |
splice site |
probably benign |
|
|
IGL02557:Nbas
|
APN |
12 |
13,411,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02815:Nbas
|
APN |
12 |
13,360,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Nbas
|
APN |
12 |
13,412,542 (GRCm39) |
missense |
probably benign |
|
|
IGL03131:Nbas
|
APN |
12 |
13,329,417 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL03214:Nbas
|
APN |
12 |
13,381,111 (GRCm39) |
splice site |
probably benign |
|
|
IGL03308:Nbas
|
APN |
12 |
13,374,349 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03368:Nbas
|
APN |
12 |
13,378,452 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL03372:Nbas
|
APN |
12 |
13,584,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03391:Nbas
|
APN |
12 |
13,533,750 (GRCm39) |
missense |
probably benign |
0.28 |
|
medvedev
|
UTSW |
12 |
13,584,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
oligarchs
|
UTSW |
12 |
13,570,751 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
putin
|
UTSW |
12 |
13,371,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
1mM(1):Nbas
|
UTSW |
12 |
13,338,729 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0057:Nbas
|
UTSW |
12 |
13,440,958 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0076:Nbas
|
UTSW |
12 |
13,374,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0153:Nbas
|
UTSW |
12 |
13,323,877 (GRCm39) |
splice site |
probably benign |
|
|
R0371:Nbas
|
UTSW |
12 |
13,381,096 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0449:Nbas
|
UTSW |
12 |
13,569,109 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0791:Nbas
|
UTSW |
12 |
13,532,634 (GRCm39) |
missense |
probably benign |
0.28 |
|
R0931:Nbas
|
UTSW |
12 |
13,381,115 (GRCm39) |
splice site |
probably benign |
|
|
R1236:Nbas
|
UTSW |
12 |
13,319,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1371:Nbas
|
UTSW |
12 |
13,532,379 (GRCm39) |
splice site |
probably benign |
|
|
R1567:Nbas
|
UTSW |
12 |
13,335,279 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1587:Nbas
|
UTSW |
12 |
13,608,686 (GRCm39) |
missense |
probably benign |
|
|
R1719:Nbas
|
UTSW |
12 |
13,610,978 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1747:Nbas
|
UTSW |
12 |
13,385,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1777:Nbas
|
UTSW |
12 |
13,563,563 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1848:Nbas
|
UTSW |
12 |
13,463,598 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1856:Nbas
|
UTSW |
12 |
13,524,230 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1891:Nbas
|
UTSW |
12 |
13,440,973 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1911:Nbas
|
UTSW |
12 |
13,616,145 (GRCm39) |
missense |
probably benign |
|
|
R1912:Nbas
|
UTSW |
12 |
13,616,145 (GRCm39) |
missense |
probably benign |
|
|
R2006:Nbas
|
UTSW |
12 |
13,464,742 (GRCm39) |
splice site |
probably null |
|
|
R2054:Nbas
|
UTSW |
12 |
13,524,207 (GRCm39) |
missense |
probably benign |
0.36 |
|
R2065:Nbas
|
UTSW |
12 |
13,616,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2089:Nbas
|
UTSW |
12 |
13,411,046 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2091:Nbas
|
UTSW |
12 |
13,411,046 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2091:Nbas
|
UTSW |
12 |
13,411,046 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2156:Nbas
|
UTSW |
12 |
13,491,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2164:Nbas
|
UTSW |
12 |
13,380,647 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R2339:Nbas
|
UTSW |
12 |
13,412,593 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2398:Nbas
|
UTSW |
12 |
13,482,946 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3806:Nbas
|
UTSW |
12 |
13,532,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3855:Nbas
|
UTSW |
12 |
13,329,415 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4019:Nbas
|
UTSW |
12 |
13,532,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4083:Nbas
|
UTSW |
12 |
13,524,192 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4201:Nbas
|
UTSW |
12 |
13,424,827 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4231:Nbas
|
UTSW |
12 |
13,443,344 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4552:Nbas
|
UTSW |
12 |
13,385,938 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4560:Nbas
|
UTSW |
12 |
13,633,528 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4728:Nbas
|
UTSW |
12 |
13,338,740 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4752:Nbas
|
UTSW |
12 |
13,532,538 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4832:Nbas
|
UTSW |
12 |
13,533,740 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4874:Nbas
|
UTSW |
12 |
13,371,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4988:Nbas
|
UTSW |
12 |
13,458,266 (GRCm39) |
missense |
probably benign |
0.45 |
|
R5020:Nbas
|
UTSW |
12 |
13,424,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5079:Nbas
|
UTSW |
12 |
13,424,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5129:Nbas
|
UTSW |
12 |
13,440,961 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5239:Nbas
|
UTSW |
12 |
13,491,519 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5299:Nbas
|
UTSW |
12 |
13,491,926 (GRCm39) |
nonsense |
probably null |
|
|
R5351:Nbas
|
UTSW |
12 |
13,610,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5389:Nbas
|
UTSW |
12 |
13,584,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5436:Nbas
|
UTSW |
12 |
13,424,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5654:Nbas
|
UTSW |
12 |
13,633,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5690:Nbas
|
UTSW |
12 |
13,386,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5842:Nbas
|
UTSW |
12 |
13,319,267 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5959:Nbas
|
UTSW |
12 |
13,338,802 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5982:Nbas
|
UTSW |
12 |
13,443,431 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6238:Nbas
|
UTSW |
12 |
13,532,596 (GRCm39) |
missense |
probably benign |
|
|
R6270:Nbas
|
UTSW |
12 |
13,374,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6363:Nbas
|
UTSW |
12 |
13,532,577 (GRCm39) |
missense |
probably benign |
|
|
R6424:Nbas
|
UTSW |
12 |
13,465,734 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6458:Nbas
|
UTSW |
12 |
13,338,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6526:Nbas
|
UTSW |
12 |
13,455,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6654:Nbas
|
UTSW |
12 |
13,533,875 (GRCm39) |
nonsense |
probably null |
|
|
R7085:Nbas
|
UTSW |
12 |
13,335,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Nbas
|
UTSW |
12 |
13,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7197:Nbas
|
UTSW |
12 |
13,570,751 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7378:Nbas
|
UTSW |
12 |
13,324,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7393:Nbas
|
UTSW |
12 |
13,443,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7425:Nbas
|
UTSW |
12 |
13,519,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7446:Nbas
|
UTSW |
12 |
13,443,499 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7481:Nbas
|
UTSW |
12 |
13,406,960 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7535:Nbas
|
UTSW |
12 |
13,329,390 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7626:Nbas
|
UTSW |
12 |
13,608,661 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7678:Nbas
|
UTSW |
12 |
13,465,662 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7912:Nbas
|
UTSW |
12 |
13,455,458 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7964:Nbas
|
UTSW |
12 |
13,406,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8193:Nbas
|
UTSW |
12 |
13,483,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8325:Nbas
|
UTSW |
12 |
13,338,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8405:Nbas
|
UTSW |
12 |
13,329,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8437:Nbas
|
UTSW |
12 |
13,616,251 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8559:Nbas
|
UTSW |
12 |
13,402,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8684:Nbas
|
UTSW |
12 |
13,386,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8826:Nbas
|
UTSW |
12 |
13,402,875 (GRCm39) |
splice site |
probably benign |
|
|
R8921:Nbas
|
UTSW |
12 |
13,463,590 (GRCm39) |
missense |
probably benign |
|
|
R8956:Nbas
|
UTSW |
12 |
13,482,923 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R9083:Nbas
|
UTSW |
12 |
13,385,856 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9172:Nbas
|
UTSW |
12 |
13,424,751 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9430:Nbas
|
UTSW |
12 |
13,371,654 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9627:Nbas
|
UTSW |
12 |
13,350,203 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
RF013:Nbas
|
UTSW |
12 |
13,329,409 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
T0722:Nbas
|
UTSW |
12 |
13,402,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Nbas
|
UTSW |
12 |
13,533,877 (GRCm39) |
missense |
probably benign |
0.06 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTACATTGTCTCCTTAGGCTG -3'
(R):5'- AGCCAGCTTCGACTTCATGG -3'
Sequencing Primer
(F):5'- AAGAAGCCATGTCTGCTGTC -3'
(R):5'- TTCGACTTCATGGCCGGC -3'
|
| Posted On |
2022-10-06 |
Incidental Mutation