Incidental Mutation 'IGL01288:Kmt2d'
ID 72811
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Kmt2d
Ensembl Gene ENSMUSG00000048154
Gene Name lysine (K)-specific methyltransferase 2D
Synonyms Mll2, C430014K11Rik, Mll4
Accession Numbers
Essential gene? Essential (E-score: 1.000) question?
Stock # IGL01288
Quality Score
Status
Chromosome 15
Chromosomal Location 98831669-98871204 bp(-) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) G to T at 98865044 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Proline to Threonine at position 282 (P282T)
Ref Sequence ENSEMBL: ENSMUSP00000135941 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000023741] [ENSMUST00000178486]
AlphaFold no structure available at present
Predicted Effect probably damaging
Transcript: ENSMUST00000023741
AA Change: P282T

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000023741
Gene: ENSMUSG00000048154
AA Change: P282T

DomainStartEndE-ValueType
low complexity region 135 145 N/A INTRINSIC
PHD 171 218 1.65e-5 SMART
RING 172 217 2.01e0 SMART
PHD 228 274 2.13e-8 SMART
RING 229 273 2.11e-3 SMART
PHD 275 321 1.57e-11 SMART
RING 276 320 2.36e0 SMART
low complexity region 430 489 N/A INTRINSIC
low complexity region 500 562 N/A INTRINSIC
low complexity region 564 613 N/A INTRINSIC
low complexity region 619 717 N/A INTRINSIC
internal_repeat_3 719 768 2.82e-8 PROSPERO
internal_repeat_3 773 822 2.82e-8 PROSPERO
low complexity region 826 842 N/A INTRINSIC
low complexity region 844 919 N/A INTRINSIC
low complexity region 958 981 N/A INTRINSIC
low complexity region 985 1023 N/A INTRINSIC
low complexity region 1069 1076 N/A INTRINSIC
low complexity region 1139 1153 N/A INTRINSIC
low complexity region 1259 1285 N/A INTRINSIC
low complexity region 1307 1314 N/A INTRINSIC
PHD 1335 1384 7.01e-9 SMART
RING 1336 1383 1.46e1 SMART
PHD 1385 1431 8.56e-13 SMART
PHD 1462 1513 1.11e-6 SMART
RING 1463 1512 1.46e1 SMART
low complexity region 1514 1538 N/A INTRINSIC
low complexity region 1567 1576 N/A INTRINSIC
low complexity region 1589 1612 N/A INTRINSIC
low complexity region 1634 1646 N/A INTRINSIC
low complexity region 1707 1719 N/A INTRINSIC
low complexity region 1883 1896 N/A INTRINSIC
low complexity region 1931 1950 N/A INTRINSIC
HMG 1969 2037 6.35e-6 SMART
low complexity region 2064 2079 N/A INTRINSIC
low complexity region 2147 2167 N/A INTRINSIC
low complexity region 2170 2181 N/A INTRINSIC
low complexity region 2306 2323 N/A INTRINSIC
low complexity region 2334 2359 N/A INTRINSIC
low complexity region 2366 2388 N/A INTRINSIC
low complexity region 2402 2419 N/A INTRINSIC
low complexity region 2546 2559 N/A INTRINSIC
low complexity region 2610 2622 N/A INTRINSIC
coiled coil region 2632 2665 N/A INTRINSIC
coiled coil region 2768 2813 N/A INTRINSIC
low complexity region 2855 2868 N/A INTRINSIC
low complexity region 2887 2899 N/A INTRINSIC
low complexity region 3151 3165 N/A INTRINSIC
low complexity region 3189 3204 N/A INTRINSIC
low complexity region 3241 3263 N/A INTRINSIC
low complexity region 3390 3400 N/A INTRINSIC
low complexity region 3629 3659 N/A INTRINSIC
coiled coil region 3712 3749 N/A INTRINSIC
low complexity region 3781 3801 N/A INTRINSIC
coiled coil region 3910 4003 N/A INTRINSIC
low complexity region 4128 4159 N/A INTRINSIC
low complexity region 4167 4183 N/A INTRINSIC
low complexity region 4226 4246 N/A INTRINSIC
low complexity region 4266 4293 N/A INTRINSIC
low complexity region 4306 4322 N/A INTRINSIC
low complexity region 4361 4378 N/A INTRINSIC
coiled coil region 4591 4613 N/A INTRINSIC
low complexity region 4661 4684 N/A INTRINSIC
low complexity region 4745 4755 N/A INTRINSIC
low complexity region 4877 4896 N/A INTRINSIC
low complexity region 4957 4983 N/A INTRINSIC
low complexity region 4989 5029 N/A INTRINSIC
low complexity region 5100 5107 N/A INTRINSIC
PHD 5142 5188 4.67e-5 SMART
RING 5143 5187 4.87e0 SMART
FYRN 5242 5285 5.07e-21 SMART
FYRC 5291 5378 2.51e-43 SMART
SET 5448 5570 5.69e-36 SMART
PostSET 5572 5588 3.58e-5 SMART
Predicted Effect probably damaging
Transcript: ENSMUST00000178486
AA Change: P282T

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000135941
Gene: ENSMUSG00000048154
AA Change: P282T

DomainStartEndE-ValueType
low complexity region 135 145 N/A INTRINSIC
PHD 171 218 1.65e-5 SMART
RING 172 217 2.01e0 SMART
PHD 228 274 2.13e-8 SMART
RING 229 273 2.11e-3 SMART
PHD 275 321 1.57e-11 SMART
RING 276 320 2.36e0 SMART
low complexity region 430 489 N/A INTRINSIC
low complexity region 500 562 N/A INTRINSIC
low complexity region 564 613 N/A INTRINSIC
low complexity region 619 717 N/A INTRINSIC
internal_repeat_3 719 768 2.82e-8 PROSPERO
internal_repeat_3 773 822 2.82e-8 PROSPERO
low complexity region 826 842 N/A INTRINSIC
low complexity region 844 919 N/A INTRINSIC
low complexity region 958 981 N/A INTRINSIC
low complexity region 985 1023 N/A INTRINSIC
low complexity region 1069 1076 N/A INTRINSIC
low complexity region 1139 1153 N/A INTRINSIC
low complexity region 1259 1285 N/A INTRINSIC
low complexity region 1307 1314 N/A INTRINSIC
PHD 1335 1384 7.01e-9 SMART
RING 1336 1383 1.46e1 SMART
PHD 1385 1431 8.56e-13 SMART
PHD 1462 1513 1.11e-6 SMART
RING 1463 1512 1.46e1 SMART
low complexity region 1514 1538 N/A INTRINSIC
low complexity region 1567 1576 N/A INTRINSIC
low complexity region 1589 1612 N/A INTRINSIC
low complexity region 1634 1646 N/A INTRINSIC
low complexity region 1707 1719 N/A INTRINSIC
low complexity region 1883 1896 N/A INTRINSIC
low complexity region 1931 1950 N/A INTRINSIC
HMG 1969 2037 6.35e-6 SMART
low complexity region 2064 2079 N/A INTRINSIC
low complexity region 2147 2167 N/A INTRINSIC
low complexity region 2170 2181 N/A INTRINSIC
low complexity region 2306 2323 N/A INTRINSIC
low complexity region 2334 2359 N/A INTRINSIC
low complexity region 2366 2388 N/A INTRINSIC
low complexity region 2402 2419 N/A INTRINSIC
low complexity region 2546 2559 N/A INTRINSIC
low complexity region 2610 2622 N/A INTRINSIC
coiled coil region 2632 2665 N/A INTRINSIC
coiled coil region 2768 2813 N/A INTRINSIC
low complexity region 2855 2868 N/A INTRINSIC
low complexity region 2887 2899 N/A INTRINSIC
low complexity region 3151 3165 N/A INTRINSIC
low complexity region 3189 3204 N/A INTRINSIC
low complexity region 3241 3263 N/A INTRINSIC
low complexity region 3390 3400 N/A INTRINSIC
low complexity region 3629 3659 N/A INTRINSIC
coiled coil region 3712 3749 N/A INTRINSIC
low complexity region 3781 3801 N/A INTRINSIC
coiled coil region 3910 4003 N/A INTRINSIC
low complexity region 4128 4159 N/A INTRINSIC
low complexity region 4167 4183 N/A INTRINSIC
low complexity region 4226 4246 N/A INTRINSIC
low complexity region 4266 4293 N/A INTRINSIC
low complexity region 4306 4322 N/A INTRINSIC
low complexity region 4361 4378 N/A INTRINSIC
coiled coil region 4591 4613 N/A INTRINSIC
low complexity region 4661 4684 N/A INTRINSIC
low complexity region 4745 4755 N/A INTRINSIC
low complexity region 4877 4896 N/A INTRINSIC
low complexity region 4957 4983 N/A INTRINSIC
low complexity region 4989 5029 N/A INTRINSIC
low complexity region 5100 5107 N/A INTRINSIC
PHD 5142 5188 4.67e-5 SMART
RING 5143 5187 4.87e0 SMART
FYRN 5242 5285 5.07e-21 SMART
FYRC 5291 5378 2.51e-43 SMART
SET 5448 5570 5.69e-36 SMART
PostSET 5572 5588 3.58e-5 SMART
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit embryonic lethality around E9.5. Mice homozygous for a conditional allele activated in different cell-types exhibit impaired adipogenesis, impaired myogenesis, perturbed germinal B cell development and promoteion of lymphomagenesis. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 46 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acsf3 G T 8: 122,780,642 (GRCm38) probably benign Het
Acsl3 G T 1: 78,699,759 (GRCm38) W490L possibly damaging Het
Ahnak A G 19: 9,002,494 (GRCm38) I381V possibly damaging Het
Aox1 A G 1: 58,294,407 (GRCm38) Y261C probably damaging Het
Ap3m2 T C 8: 22,803,915 (GRCm38) T40A probably benign Het
Arfgef1 C T 1: 10,213,211 (GRCm38) A158T possibly damaging Het
Atp1a4 T C 1: 172,257,907 (GRCm38) E43G possibly damaging Het
Cog5 C T 12: 31,886,206 (GRCm38) T584I probably benign Het
Cpa1 G A 6: 30,640,583 (GRCm38) V75M probably damaging Het
Cul7 A G 17: 46,657,807 (GRCm38) probably benign Het
Dop1b T C 16: 93,739,293 (GRCm38) I93T possibly damaging Het
Dyrk2 T C 10: 118,860,699 (GRCm38) Y218C probably damaging Het
Efr3b T C 12: 3,982,865 (GRCm38) Y164C probably damaging Het
Etos1 C A 7: 130,772,205 (GRCm38) probably benign Het
Fam13a A G 6: 58,956,727 (GRCm38) Y293H probably damaging Het
Gde1 A T 7: 118,691,640 (GRCm38) V154D possibly damaging Het
Glyat A G 19: 12,650,355 (GRCm38) T105A possibly damaging Het
Il1f8 A T 2: 24,159,913 (GRCm38) I179L probably benign Het
Kif21b C T 1: 136,172,184 (GRCm38) T1492M probably benign Het
Lgi4 A G 7: 31,069,043 (GRCm38) E489G probably benign Het
Lipn A C 19: 34,079,035 (GRCm38) E260D probably benign Het
Mdn1 A G 4: 32,730,864 (GRCm38) D2911G probably benign Het
Nab2 C T 10: 127,665,109 (GRCm38) R38Q probably damaging Het
Or1e35 A T 11: 73,907,313 (GRCm38) Y60N probably damaging Het
Or4c1 A T 2: 89,303,472 (GRCm38) V40E possibly damaging Het
Or4p22 T A 2: 88,487,248 (GRCm38) I172K probably damaging Het
Or52i2 A G 7: 102,670,651 (GRCm38) T244A probably damaging Het
Or5t16 C A 2: 86,988,254 (GRCm38) M307I probably benign Het
Or6f2 T C 7: 140,176,615 (GRCm38) L165P probably damaging Het
Osbpl6 T C 2: 76,564,823 (GRCm38) S337P probably damaging Het
Phf8 T C X: 151,547,925 (GRCm38) probably null Het
Pik3c2b C T 1: 133,094,805 (GRCm38) H1162Y probably damaging Het
Plek2 T C 12: 78,894,953 (GRCm38) D134G possibly damaging Het
Rnf139 G A 15: 58,899,179 (GRCm38) R351H probably damaging Het
Shld2 A T 14: 34,259,643 (GRCm38) Y513N probably benign Het
Skint5 T C 4: 113,524,135 (GRCm38) probably benign Het
Slc12a9 C T 5: 137,330,938 (GRCm38) probably null Het
St5 A G 7: 109,539,822 (GRCm38) I668T probably damaging Het
Stradb C A 1: 58,992,301 (GRCm38) H216N possibly damaging Het
Tex15 C T 8: 33,571,384 (GRCm38) H281Y probably benign Het
Tg G T 15: 66,736,276 (GRCm38) V237L possibly damaging Het
Tns1 T A 1: 73,953,810 (GRCm38) T570S probably damaging Het
Tpm1 C T 9: 67,036,055 (GRCm38) R105H probably damaging Het
Wdfy3 G T 5: 101,901,991 (GRCm38) probably null Het
Zc3h12c A G 9: 52,117,651 (GRCm38) probably benign Het
Zmynd8 T A 2: 165,812,814 (GRCm38) S584C probably damaging Het
Other mutations in Kmt2d
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00229:Kmt2d APN 15 98,862,333 (GRCm38) missense unknown
IGL00927:Kmt2d APN 15 98,845,009 (GRCm38) unclassified probably benign
IGL01123:Kmt2d APN 15 98,837,148 (GRCm38) missense unknown
IGL01538:Kmt2d APN 15 98,860,657 (GRCm38) unclassified probably benign
IGL01575:Kmt2d APN 15 98,846,855 (GRCm38) utr 3 prime probably benign
IGL01584:Kmt2d APN 15 98,856,369 (GRCm38) unclassified probably benign
IGL01750:Kmt2d APN 15 98,853,168 (GRCm38) unclassified probably benign
IGL02163:Kmt2d APN 15 98,835,228 (GRCm38) unclassified probably benign
IGL02209:Kmt2d APN 15 98,854,567 (GRCm38) unclassified probably benign
IGL02253:Kmt2d APN 15 98,858,175 (GRCm38) unclassified probably benign
IGL02271:Kmt2d APN 15 98,866,428 (GRCm38) missense possibly damaging 0.89
IGL02291:Kmt2d APN 15 98,865,492 (GRCm38) splice site probably benign
IGL02448:Kmt2d APN 15 98,844,110 (GRCm38) unclassified probably benign
IGL02472:Kmt2d APN 15 98,850,077 (GRCm38) missense probably benign 0.23
IGL02496:Kmt2d APN 15 98,857,558 (GRCm38) unclassified probably benign
IGL02527:Kmt2d APN 15 98,841,747 (GRCm38) unclassified probably benign
IGL02576:Kmt2d APN 15 98,864,120 (GRCm38) missense unknown
IGL02597:Kmt2d APN 15 98,863,831 (GRCm38) missense unknown
IGL02609:Kmt2d APN 15 98,851,793 (GRCm38) unclassified probably benign
IGL03085:Kmt2d APN 15 98,839,940 (GRCm38) unclassified probably benign
IGL03102:Kmt2d APN 15 98,855,543 (GRCm38) missense probably benign
IGL03123:Kmt2d APN 15 98,861,771 (GRCm38) missense unknown
G1citation:Kmt2d UTSW 15 98,849,459 (GRCm38) unclassified probably benign
R0091:Kmt2d UTSW 15 98,844,479 (GRCm38) unclassified probably benign
R0136:Kmt2d UTSW 15 98,854,278 (GRCm38) unclassified probably benign
R0243:Kmt2d UTSW 15 98,850,137 (GRCm38) unclassified probably benign
R0276:Kmt2d UTSW 15 98,850,311 (GRCm38) unclassified probably benign
R0477:Kmt2d UTSW 15 98,853,581 (GRCm38) unclassified probably benign
R0478:Kmt2d UTSW 15 98,853,581 (GRCm38) unclassified probably benign
R0586:Kmt2d UTSW 15 98,835,207 (GRCm38) unclassified probably benign
R0632:Kmt2d UTSW 15 98,853,581 (GRCm38) unclassified probably benign
R0678:Kmt2d UTSW 15 98,850,413 (GRCm38) unclassified probably benign
R0780:Kmt2d UTSW 15 98,862,857 (GRCm38) missense unknown
R0891:Kmt2d UTSW 15 98,852,691 (GRCm38) unclassified probably benign
R1136:Kmt2d UTSW 15 98,857,765 (GRCm38) unclassified probably benign
R1417:Kmt2d UTSW 15 98,866,430 (GRCm38) missense probably damaging 0.99
R1499:Kmt2d UTSW 15 98,844,938 (GRCm38) unclassified probably benign
R1510:Kmt2d UTSW 15 98,856,377 (GRCm38) unclassified probably benign
R1586:Kmt2d UTSW 15 98,865,053 (GRCm38) splice site probably benign
R1640:Kmt2d UTSW 15 98,845,057 (GRCm38) unclassified probably benign
R1714:Kmt2d UTSW 15 98,862,950 (GRCm38) missense unknown
R1725:Kmt2d UTSW 15 98,845,234 (GRCm38) unclassified probably benign
R1728:Kmt2d UTSW 15 98,865,132 (GRCm38) missense probably damaging 1.00
R1729:Kmt2d UTSW 15 98,865,132 (GRCm38) missense probably damaging 1.00
R1741:Kmt2d UTSW 15 98,845,234 (GRCm38) unclassified probably benign
R1744:Kmt2d UTSW 15 98,865,047 (GRCm38) missense probably damaging 0.99
R1746:Kmt2d UTSW 15 98,864,378 (GRCm38) missense probably damaging 0.97
R1753:Kmt2d UTSW 15 98,843,482 (GRCm38) unclassified probably benign
R1782:Kmt2d UTSW 15 98,857,548 (GRCm38) unclassified probably benign
R1789:Kmt2d UTSW 15 98,852,074 (GRCm38) unclassified probably benign
R1802:Kmt2d UTSW 15 98,862,985 (GRCm38) missense unknown
R1808:Kmt2d UTSW 15 98,866,686 (GRCm38) missense probably damaging 1.00
R1822:Kmt2d UTSW 15 98,861,780 (GRCm38) missense unknown
R1831:Kmt2d UTSW 15 98,855,343 (GRCm38) missense probably damaging 0.97
R1920:Kmt2d UTSW 15 98,855,591 (GRCm38) missense probably damaging 1.00
R1920:Kmt2d UTSW 15 98,855,590 (GRCm38) missense probably damaging 0.96
R1956:Kmt2d UTSW 15 98,859,590 (GRCm38) unclassified probably benign
R2100:Kmt2d UTSW 15 98,846,480 (GRCm38) unclassified probably benign
R2120:Kmt2d UTSW 15 98,839,529 (GRCm38) unclassified probably benign
R2188:Kmt2d UTSW 15 98,839,300 (GRCm38) unclassified probably benign
R2191:Kmt2d UTSW 15 98,861,049 (GRCm38) critical splice donor site probably null
R2234:Kmt2d UTSW 15 98,865,248 (GRCm38) missense probably damaging 0.98
R2422:Kmt2d UTSW 15 98,862,266 (GRCm38) missense unknown
R2762:Kmt2d UTSW 15 98,852,055 (GRCm38) unclassified probably benign
R2895:Kmt2d UTSW 15 98,843,939 (GRCm38) unclassified probably benign
R3624:Kmt2d UTSW 15 98,842,902 (GRCm38) unclassified probably benign
R3791:Kmt2d UTSW 15 98,844,149 (GRCm38) unclassified probably benign
R3794:Kmt2d UTSW 15 98,837,359 (GRCm38) unclassified probably benign
R3871:Kmt2d UTSW 15 98,851,021 (GRCm38) unclassified probably benign
R3958:Kmt2d UTSW 15 98,855,549 (GRCm38) missense possibly damaging 0.69
R3983:Kmt2d UTSW 15 98,846,046 (GRCm38) unclassified probably benign
R4211:Kmt2d UTSW 15 98,840,189 (GRCm38) unclassified probably benign
R4212:Kmt2d UTSW 15 98,845,003 (GRCm38) unclassified probably benign
R4240:Kmt2d UTSW 15 98,844,571 (GRCm38) unclassified probably benign
R4246:Kmt2d UTSW 15 98,840,089 (GRCm38) unclassified probably benign
R4361:Kmt2d UTSW 15 98,863,670 (GRCm38) missense unknown
R4388:Kmt2d UTSW 15 98,853,626 (GRCm38) unclassified probably benign
R4602:Kmt2d UTSW 15 98,850,259 (GRCm38) unclassified probably benign
R4606:Kmt2d UTSW 15 98,839,716 (GRCm38) unclassified probably benign
R4658:Kmt2d UTSW 15 98,852,529 (GRCm38) unclassified probably benign
R4840:Kmt2d UTSW 15 98,861,894 (GRCm38) missense unknown
R4895:Kmt2d UTSW 15 98,844,487 (GRCm38) unclassified probably benign
R4906:Kmt2d UTSW 15 98,849,539 (GRCm38) unclassified probably benign
R4976:Kmt2d UTSW 15 98,847,194 (GRCm38) utr 3 prime probably benign
R5093:Kmt2d UTSW 15 98,856,162 (GRCm38) missense probably damaging 1.00
R5119:Kmt2d UTSW 15 98,847,194 (GRCm38) utr 3 prime probably benign
R5160:Kmt2d UTSW 15 98,840,224 (GRCm38) unclassified probably benign
R5260:Kmt2d UTSW 15 98,842,860 (GRCm38) unclassified probably benign
R5274:Kmt2d UTSW 15 98,854,230 (GRCm38) unclassified probably benign
R5450:Kmt2d UTSW 15 98,855,086 (GRCm38) missense probably damaging 1.00
R5461:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5462:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5463:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5465:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5467:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5481:Kmt2d UTSW 15 98,862,005 (GRCm38) missense unknown
R5509:Kmt2d UTSW 15 98,839,676 (GRCm38) unclassified probably benign
R5534:Kmt2d UTSW 15 98,837,357 (GRCm38) unclassified probably benign
R5536:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5537:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5538:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5546:Kmt2d UTSW 15 98,853,068 (GRCm38) unclassified probably benign
R5595:Kmt2d UTSW 15 98,850,024 (GRCm38) unclassified probably benign
R5645:Kmt2d UTSW 15 98,844,397 (GRCm38) unclassified probably benign
R5679:Kmt2d UTSW 15 98,854,272 (GRCm38) unclassified probably benign
R5710:Kmt2d UTSW 15 98,854,106 (GRCm38) unclassified probably benign
R5755:Kmt2d UTSW 15 98,863,646 (GRCm38) missense unknown
R5817:Kmt2d UTSW 15 98,862,363 (GRCm38) missense unknown
R5841:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5842:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5843:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5844:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R5845:Kmt2d UTSW 15 98,852,109 (GRCm38) unclassified probably benign
R6122:Kmt2d UTSW 15 98,860,692 (GRCm38) unclassified probably benign
R6612:Kmt2d UTSW 15 98,845,858 (GRCm38) unclassified probably benign
R6718:Kmt2d UTSW 15 98,849,586 (GRCm38) unclassified probably benign
R6718:Kmt2d UTSW 15 98,850,539 (GRCm38) unclassified probably benign
R6822:Kmt2d UTSW 15 98,849,459 (GRCm38) unclassified probably benign
R6866:Kmt2d UTSW 15 98,857,393 (GRCm38) unclassified probably benign
R6950:Kmt2d UTSW 15 98,840,020 (GRCm38) unclassified probably benign
R7089:Kmt2d UTSW 15 98,850,272 (GRCm38) missense unknown
R7120:Kmt2d UTSW 15 98,861,065 (GRCm38) missense unknown
R7131:Kmt2d UTSW 15 98,849,616 (GRCm38) unclassified probably benign
R7177:Kmt2d UTSW 15 98,850,386 (GRCm38) missense unknown
R7194:Kmt2d UTSW 15 98,843,833 (GRCm38) missense unknown
R7252:Kmt2d UTSW 15 98,844,266 (GRCm38) missense unknown
R7282:Kmt2d UTSW 15 98,854,104 (GRCm38) missense unknown
R7307:Kmt2d UTSW 15 98,849,418 (GRCm38) missense unknown
R7313:Kmt2d UTSW 15 98,856,623 (GRCm38) missense unknown
R7394:Kmt2d UTSW 15 98,856,384 (GRCm38) missense unknown
R7404:Kmt2d UTSW 15 98,845,495 (GRCm38) missense unknown
R7409:Kmt2d UTSW 15 98,855,354 (GRCm38) missense probably damaging 1.00
R7414:Kmt2d UTSW 15 98,839,856 (GRCm38) missense unknown
R7534:Kmt2d UTSW 15 98,852,018 (GRCm38) missense unknown
R7575:Kmt2d UTSW 15 98,849,611 (GRCm38) unclassified probably benign
R7650:Kmt2d UTSW 15 98,850,870 (GRCm38) missense unknown
R7687:Kmt2d UTSW 15 98,862,120 (GRCm38) missense unknown
R7699:Kmt2d UTSW 15 98,843,719 (GRCm38) missense unknown
R7700:Kmt2d UTSW 15 98,843,719 (GRCm38) missense unknown
R7765:Kmt2d UTSW 15 98,852,334 (GRCm38) missense unknown
R7797:Kmt2d UTSW 15 98,864,406 (GRCm38) missense probably benign 0.24
R7803:Kmt2d UTSW 15 98,862,923 (GRCm38) missense unknown
R7952:Kmt2d UTSW 15 98,850,768 (GRCm38) missense unknown
R8054:Kmt2d UTSW 15 98,843,925 (GRCm38) missense unknown
R8084:Kmt2d UTSW 15 98,842,064 (GRCm38) missense unknown
R8089:Kmt2d UTSW 15 98,842,869 (GRCm38) missense unknown
R8133:Kmt2d UTSW 15 98,864,942 (GRCm38) missense probably damaging 1.00
R8138:Kmt2d UTSW 15 98,843,653 (GRCm38) missense unknown
R8343:Kmt2d UTSW 15 98,852,597 (GRCm38) missense unknown
R8681:Kmt2d UTSW 15 98,846,067 (GRCm38) missense unknown
R8694:Kmt2d UTSW 15 98,844,734 (GRCm38) missense unknown
R8837:Kmt2d UTSW 15 98,864,167 (GRCm38) missense unknown
R8855:Kmt2d UTSW 15 98,856,356 (GRCm38) missense unknown
R8934:Kmt2d UTSW 15 98,861,886 (GRCm38) missense unknown
R9100:Kmt2d UTSW 15 98,849,951 (GRCm38) missense unknown
R9158:Kmt2d UTSW 15 98,843,139 (GRCm38) missense unknown
R9190:Kmt2d UTSW 15 98,852,015 (GRCm38) missense unknown
R9222:Kmt2d UTSW 15 98,849,443 (GRCm38) missense unknown
R9263:Kmt2d UTSW 15 98,849,618 (GRCm38) frame shift probably null
R9336:Kmt2d UTSW 15 98,845,816 (GRCm38) missense unknown
R9397:Kmt2d UTSW 15 98,850,113 (GRCm38) missense unknown
R9415:Kmt2d UTSW 15 98,839,705 (GRCm38) missense unknown
R9482:Kmt2d UTSW 15 98,865,165 (GRCm38) missense probably damaging 1.00
R9529:Kmt2d UTSW 15 98,839,768 (GRCm38) missense unknown
R9610:Kmt2d UTSW 15 98,845,176 (GRCm38) unclassified probably benign
R9611:Kmt2d UTSW 15 98,845,173 (GRCm38) unclassified probably benign
R9611:Kmt2d UTSW 15 98,845,176 (GRCm38) unclassified probably benign
R9612:Kmt2d UTSW 15 98,845,176 (GRCm38) unclassified probably benign
R9613:Kmt2d UTSW 15 98,845,176 (GRCm38) unclassified probably benign
R9644:Kmt2d UTSW 15 98,845,504 (GRCm38) missense unknown
R9716:Kmt2d UTSW 15 98,843,402 (GRCm38) missense unknown
R9763:Kmt2d UTSW 15 98,845,176 (GRCm38) unclassified probably benign
R9782:Kmt2d UTSW 15 98,866,716 (GRCm38) missense probably damaging 1.00
X0018:Kmt2d UTSW 15 98,852,922 (GRCm38) unclassified probably benign
X0024:Kmt2d UTSW 15 98,853,053 (GRCm38) unclassified probably benign
X0062:Kmt2d UTSW 15 98,849,819 (GRCm38) unclassified probably benign
Z1187:Kmt2d UTSW 15 98,851,744 (GRCm38) missense unknown
Z1188:Kmt2d UTSW 15 98,851,744 (GRCm38) missense unknown
Z1189:Kmt2d UTSW 15 98,851,744 (GRCm38) missense unknown
Z1190:Kmt2d UTSW 15 98,851,744 (GRCm38) missense unknown
Z1192:Kmt2d UTSW 15 98,851,744 (GRCm38) missense unknown
Posted On 2013-10-07